PROGRAM

5th Meeting

Skeletal Endocrinology Main Hall ♦ School of Medicine ♦University of Brescia 20th - 21st September 2012

PROGRAM CHAIR John P. Bilezikian ♦ Ernesto Canalis ♦ Andrea Giustina INTERNATIONAL ADVISORY BOARD Robert A. Adler (Richmond, VA USA) John P. Bilezikian (New York, NY USA) Ernesto Canalis (Hartford, CT USA) Felipe F. Casanueva (Santiago de Compostela, E) Philippe Chanson (Paris, FR) Juliet Compston (Cambridge, UK) Lorenza Hofbauer (Dresden, D) Stavros Manolagas (Little Rock, AR USA) Roberto Pacifici (Atlanta, GA USA)

EXECUTIVE COUNCIL HONORARY PRESIDENT Alberto Angeli (Turin, Italy) PRESIDENT Andrea Giustina (Brescia, Italy)

PROGRAM

SECRETARY TREASURER Alberto Papa (Brescia, Italy) COUNCIL MEMBERS Gaetano Lombardi (Naples, Italy) Luigi Moro (Trieste, Italy) Ranuccio Nuti (Siena, Italy) Luigi Sinigaglia (Milan, Italy) Massimo Terzolo (Torino, Italy)

Preliminary Program Thursday, September 20th 2012

Thursday, September 20th 2012

09.00 am – 4.30 pm Pre-Course ♦ In-Training / Postgraduate Fellows (max 30 participants) Infiltrative

(With the unconditioned support of Abiogen Pharma)

4.10 – 4.20 pm

Lecture ♦

Ibandronate

4.30 – 5.00 pm

Lecture ♦

Clodronate

5.00 – 7.00 pm

Session 1 ♦ Basic

(With the unconditioned support of Pfizer)

(With the unconditioned support of Abiogen Pharma)

Estrogens and Immune System Notch and the Skeleton Molecular Basis of the Aging Skeleton 7.00 – 7.30 pm

Opening Lecture Denosumab: an Update on Long-Term Efficacy and Safety

PROGRAM

7.30 pm

Opening Cerimony and Cocktail

Friday, September 21st 2012

8.30 – 10.30 am

SESSION 2 ♦ Vitamin D Epidemiology and Diagnosis of Hypovitaminosis D Skeletal and Extraskeletal Effects of Vitamin D How Much Vitamin D We Need and What

10.30 – 11.00 am Coffee Break

Friday, September 21st 2012

11.00 am – 12.30 pm SESSION 3 ♦ Anti-Resorptive Therapies Bisphosphonates SERMs Odanacatib 12.30 – 1.15 pm

ORAL COMUNICATIONS

01.15 – 02.30 pm Lunch 1.45 - 2.30 pm Poster Session 2.30 – 4.00 pm

SESSION 4 ♦ Anabolic Therapies for Osteoporosis Anabolic Treatment with Teriparatide and PTH 1-84 New PTH: Modalities, Duration, Combinations Biological Treatments: Anti-Sclerostin /Anti-Myostatin Antibodies

4.00 – 6.00 pm

SESSION 5 ♦ Hypoparathyroidism Genetics Diagnosis and Treatment Follow Up Causes and Clinical Presentation New Therapies Skeletal Manifestations of Hypoparathyroidism

6.00 – 6.30 pm

Closing Lecture Primary Hyperparathyroidism

6.30 – 7.00 pm

Closing Remarks

FACULTY

CHAIRMEN AND INVITED SPEAKERS S. Adami (Verona, Italy) R. A. Adler (Richmond, VA USA) E. Agabiti Rosei (Brescia, Italy) A. Angeli (Turin, Italy) M. Bevilacqua (Milan, Italy) G. Bianchi (Genoa, Italy) J. P. Bilezikian (New York, NY USA) M.L. Brandi (Florence, Italy) E. Canalis (Hartford, CT USA) D. Cocchi (Milan, Italy) J. Compston (Cambridge, UK) B. Dawson-Hughes (Boston, MA USA) A. Diez Perez (Barcelona, E) D. Dempster (New York, NY USA) L. A. Fitzpatrick (Philadelphia, PA USA) B. Frediani (Siena, Italy) M. Gambacciani (Pisa, Italy) A. Giustina (Brescia, Italy) L. Hofbauer (Dresden, Germany) G. Isaia (Torin, Italy) G. Lombardi (Naples, Italy) S. Manolagas (Little Rock, AR USA) C. Marcocci (Pisa, Italy) S. Minisola (Rome, Italy) L. Moro (Trieste, Italy) L. Mosekilde (Aarhus, Denmark) R. Nuti (Siena, Italy) S. Ortolani (Milan, Italy) R. Pacifici (Atlanta, GA USA) S. E. Papapoulos (Leiden, Netherlands)

ACULTY

A. Scillitani (S.G. Rotondo, Italy) L. Sinigaglia (Milan, Italy) F. M. Ulivieri (Milan, Italy)

BRESCIA WELCOMES YOU TO THE 5TH SKELETAL ENDOCRINOLOGY MEETING Brescia, called “the the Lioness of Italy,” Italy is a dynamic, hardworking city whose inhabitants are famous for their tenacity and dedication to work. The city is also able to display a rich heritage of history and art, which spans from prehistoric times to the present. Tourists will be fascinated by the atmosphere created by its airy piazzas and picturesque lanes, its fountains and aristocratic residences, the intimacy of its cloisters and the art treasures waiting to be discovered in its churches and museums. Brescia is located half-way between Milan and Venice; it is well served by highways, trains and airports, making it quickly accessible. For all wine lovers, Brescia area offers the famous wines of Franciacorta, Franciacorta an area South of Lake Iseo: whites, rosés and reds, or a prestigious sparkling wine. Franciacorta DOCG is the most prized Italian sparkling wine.

GENERAL INFORMATION MEETING VENUE Main Hall ♦School of Medicine ♦ University of Brescia Address: Viale Europa,11 25123 Brescia, Italy

CME ACCREDITATION The 5TH Meeting Skeletal Endocrinology program will be submitted for accreditation by the European Accreditation Council for Continuing Medical Education (EACCME) and the Italian Educazione Continua in Medicina (ECM) for Physician (Medico Chirurgo) Provider: IN&FO&MED srl Via Melchiorre Gioia, 82 20125 Milano ph. +39 02 89693755 e mail:[email protected]

ATTENDANCE CERTIFICATE Attendance Certificate can be collected at registration desk only at the end of the Meeting.

LANGUAGE The official language is English. Italian/English/Italian translation will be provided.

WEBSITE For further information, please visit the official website of the Meeting: www.gioseg.org

REGISTRATION FEE REGISTRATION FEE (Current VAT 21% included) B Y JULY 5TH 2012 Delegate Delegate UNDER 35

€ 302,00 Free

FROM JULY 6TH UNTIL SEPTEMBER 8TH € 363,00 Free

ON S ITE € 400,00 Free

Identity Document (ID) is required for delegates UNDER 35. Registration fee includes: Congress Kit, Certificate of Attendance, Opening Ceremony and Cocktail, Lunches and Coffee Breaks mentioned in program. Registration Form is available on website www.gioseg.org. Mail: i n f o g i o s e g @ a i c g r o u p . i t - c/o A.I.C. Asti Incentives & Congressi Piazza San Uomobono, 30 – 56126 Pisa Italy - Phone +39 050 598808 Fax +39 050 598688

LIABILITY & INSURANCE The registration fees do not include the insurance of participants against personal accidents, sickness, cancellations by any party, theft, loss or damage to personal belongings. Participants are advised to take out adequate personal insurance to cover travel, accommodation, cancellation and personal effects.

COMMERCIAL EXHIBITION The exhibition will take place in the foyer of the Venue. Exhibitors will have the chance to meet with the delegates.

INVITATION LETTER If you need an Invitation Letter, please fill section on Registration Form. Form. Pre-registration is required.

CONFIRMATION Confirmation will be sent to all participants by e-mail after receipt of registration.

PAYMENT A complete Registration Form, along with full payment is required in order to be processed. Registrations without full payment will not be processed. If you are faxing your registration, do not mail or you may be double charged.

CANCELLATION & REFUND Requests for refund must be received within Friday, Friday August 10th, 2012 by email to: [email protected] All refunds will be sent after the Meeting. No refund will apply for cancellations received after August 10 th, 2012. 2012

SCIENTIFIC GUIDELINES PRESENTATION GUIDELINES Speakers must adhere strictly to the scheduled times according to program. Only computer projection will be available. No overhead or slide projectors will be available in meeting rooms, and it will not be possible to use personal laptops. Speakers are kindly requested to use PowerPoint ( Windows). The uploading of DVD movies is NOT supported. We recommend using ".gif" and ".jpg" formats for images. Other types of extension will be accepted, provided that they are recognized by PowerPoint. Please download your presentations by using USB pens at least 2 hours before speech at the Slide Center. www.gioseg.org) G.I.O.S.E.G. would appreciate to publish on his official website ((www.gioseg.org www.gioseg.org ) all Meeting presentations, presentations, therefore a Copyright Authorization for the speech will be requested to all speakers.

ABSTRACT SUBMISSION GUIDELINES All Abstract Submitters must be registered to the Meeting. Abstracts submission (available only on website: www.gioseg.org) starts on April 1st and ends on June 30th 2012. Abstracts can be submitted in English or Italian. Once submitted no revisions/changes will be allowed. The whole abstract (abstract titles, Authors, Institutions, Abstract body. Figures, tables disclosures) Should fit in a A4 page (2.5cm layout), written in word format typed using single line spacing (font style: Times New Roman – font size: 12). The document should include the following items in this order: • Abstract title in UPPERCASE (please do not use abbreviation) • author's first and last name (please, refer to multiple author's affiliations with superscript numbers placed immediately after each author’s name); • author's affiliation; • abstract body Figures (JPEG and TIFF, only) and Tables can be embedded in the text. The first author should provide Disclosure information at the bottom of the abstract.

Please, use generic names. Commercial drug names may not be used. Check the spelling and grammar carefully. Direct reproduction from your electronically submitted abstract text means that any errors in spelling, grammar or scientific data will be reproduced as submitted. Abstracts not in accordance with the above instructions will not be considered. Authors will receive an email indicating the status of their abstract by August 1 st 2012, 2012 along with instructions for oral or poster presentation. By submitting an abstract the author (s) agree to transfer all copyrights to the G.I.O.S.E.G. For further information please contact: [email protected]

ORAL COMMUNICATION GUIDELINES Time available for each presentation is 7’ speech and 3’ discussion. Speakers must adhere strictly to the scheduled times according to program. Speakers are kindly requested to use PowerPoint ( Windows). The uploading of DVD movies is NOT supported. We recommend using ".gif" and ".jpg" formats for images. Other types of extension will be accepted, provided that they are recognized by PowerPoint Please download your presentations by using USB pens at least 2 hours before speech at the Slide Center. All Oral Communication Speaker must be registered to the Meeting. By submitting an abstract the author (s) agree to transfer all copyrights to the G.I.O.S.E.G.

POSTER GUIDELINES Papers must be posted within Thursday, 20th September at 9.00 am Poster Panel size is 90 cm large x 130 cm high Please remember (if you haven't provided yet) that 1st author/presenter should be in order with registration. For further information please contact: [email protected]

SCIENTIFIC SECRETARIAT C.R.O.M.O.

(C CENTRO DI RICERCA PER L’O OSTEOPOROSI E METABOLISMO OSSEO)

Dott. Mauro Doga ♦ Dott. Gherardo Mazziotti ♦ Dott.ssa Teresa Porcelli

Servizio di Endocrinologia ♦ A.O. Spedali Civili di Brescia ♦ P.O. Montichiari Via. Ciotti, 154 25018 Montichiari (BS) - Tel. 030 9981367 ♦ Fax 030 9963477 (Rif. Manuela)

ORGANIZING SECRETARIAT A.I.C. ASTI INCENTIVES & CONGRESSI Piazza San Uomobono, 30 56126 Pisa – Italy Tel. +39050598808 Fax +39050598688 Email: [email protected]

HOTEL ACCOMMODATION The Organizing Secretariat has reserved rooms in 4 and 3 stars Hotels in Brescia (walking distance from the meeting venue). For request please fill section on Registration Form.

RESERVATION Reservations are made on a first-come, first-served basis therefore early reservation is recommended. Receipt and confirmation will be sent by e-mail after deposit payment.

HOW TO REACH BRESCIA BY TRAIN Railway lines:

Milano - Venezia Lecco - Bergamo - Brescia Cremona - Brescia Parma - Piadena - Brescia Roma - Cremona – Brescia

BY CAR Motorway A4: Milano – Venezia Exits: Brescia Centro or Brescia Ovest Motorway A21: Torino – Piacenza – Brescia Exit: Brescia Centro

BY PLANE Airports:

Montichiari (Brescia) 20 Km ♦ half hour Orio al Serio (Bergamo) 56 Km ♦ 40 min Villafranca (Verona) 65 Km ♦ 1 hour Linate (Milan) 95 Km ♦ 1½ hour

Due to technical, scientific or organizing purposes the Organizing Secretariat can modify the program any time