Dicle Tıp Derg / Dicle Med J

E. Sütken et al.

1 Cilt/Vol 37, No 1, 1-7

ORIGINAL RESEARCH / ÖZGÜN ARAŞTIRMA

Lipid profile and levels of homocysteine, leptin, fibrinogen and C-reactive protein in hyperthyroid patients before and after treatment Hipertiroid hastalarda tedavi öncesi ve sonrası lipid profili ile homosistein, leptin, fibrinojen ve C-reaktif protein düzeyleri Emine Sütken1, Aysen Akalın2, Filiz Özdemir3, Ömer Çolak1 Osmangazi University Medical Faculty, 1Biochemistry and 2Endocrinology, Anadolu University Pharmacy Faculty Biochemistry Dept.

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ABSTRACT

ÖZET

Objectives: The present study was carried out to determine whether thyroid hormones affect lipid profile and levels of erithrocyte sedimentation rate (ESR), serum total homocysteine (t-hcy), leptin, fibrinogen, C-reactive protein (CRP in patients with hyperthyroidism. Materials and methods: This study was carried out on 23 hyperthroid subjects (3 men / 20 women, mean age 41.8 ± 2.4 years). Serum levels of homocysteine, leptin, fibrinogen, CRP, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and ESR were measured and body mass index (BMI) were calculated before and after treatment of hyperthyroidism. Results: Pretreatment t-hcy, TC, LDL-C, HDL-C levels and BMI of patients were significantly lower than those of the post-treatment (p