11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic

11th Central European Congress of Rheumatology 8th – 10th December 2016, Prague, Czech Republic Clarion Congress Hotel Prague

SCIENTIFIC PROGRAM

Thursday, 8th December 2016 Arrivals, registration.

8:00 -

20:00

9:30 -

10:00

0:30

Break (foyer Lobby)

10:00 -

11:30

1:30

Meeting of Biology Treatment Centres of CR (Nadir)

11:30 -

12:30

1:00

Lunch for Participants of Meeting of Biology Treatment Centres (foyer Lobby)

12:30 -

13:40

Opening Session Chair: Vencovský J, Pavelka K.

Hall Zenit

12:30 13:00 -

13:00 13:20

0:30 0:20

Opening O 1. Epigenetics Regulating our Cells and Mind in Health and Disease. Gay S (Department of Rheumatology, University Hospital Zurich, Switzerland)

13:20 -

13:40

0:20

O 2. Mentoring in the Global World of Science. Gay R (Department of Rheumatology, University Hospital Zurich, Switzerland)

13:40 -

13:45

0:05

Break - foyer Lobby

13:45 -

15:15

General Session 1: Systemic Sclerosis Chair: Distler O, Tomčík M.

Hall Zenit

13:45 -

14:05

0:20

O 3. Advances in Treatment of Scleroderma – from Bench to Bedside. Distler O (Department of Rheumatology, University Hospital Zurich, Switzerland)

14:05 -

14:25

0:20

O 4. Efficacy of an Intensive 24-week Physiotherapy Programme in Scleroderma Patients Preliminary Data from a Single-center Controlled Study. Tomčík M (Institute of Rheumatology, Dept. of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic)

14:25 -

14:45

0:20

O 5. Current Disease Activity Indices in Systemic Sclerosis. Bečvář R (Institute of Rheumatology, Prague, Czech Republic)

14:45 -

14:55

0:10

O 6. Eradication of Helicobacter Pylori Reduces Disease Severity and Activity in Systemic Sclerosis Patients Radić M (Division of Rheumatology and Clinical Immunology, Center of excellence for Systemic Sclerosis in Croatia, University Hospital Center Split, Croatia)

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic 14:55 -

15:05

0:10

O 7. Histologic Characteristics of Vasculitis in Systemic Sclerosis- a Postmortem Study of 11 Systemic Sclerosis Patients Bély M (Department of Pathology, Hospital of the Order of the Brothers of Saint John of God in Budapest, Hungary)

15:05 -

15:15

0:10

O 8. Psychological Profile Detected by MMPI-IIand BDI-II Tests by Patient with Scleroderma Smržová A (3rd Department Of Internal Medicine – Nephrology, Rheumatology And Endocrinology, Faculty Hospital and University Palacky Olomouc, Czech Republic)

15:15 -

15:45

0:30

Break - foyer Lobby

15:45 -

17:15

General Session 2: Cardiovascular Manifestations of Rheumatic Diseases Chair: Anic B, Morović-Vergles J

Hall Zenit

15:45 -

16:05

0:20

O 9. Impact of Treatment with Biological Disease Modifying Antiinflammatory Drugs on Atherosclerosis in Rheumatoid Arthritis Patients. Holc I, Pahor A (University Clinical Center Maribor, Maribor, Slovenia)

16:05 -

16:25

0:20

O 10. Association between Anti-cyclic Citrullinated Peptide Antibodies and Myocardial Involvement in Patients with Active Rheumatoid Arthritis. Marasović-Krstulović D, Martinović-Kaliterna D (University Hospital Center Split, Split, Croatia)

16:25 -

16:45

0:20

O 11. Differences in the Prevalence of Arterial Hypertension and Metabolic Syndrome in Patients with Rheumatoid Arthritis and Patients with Osteoarthritis: The Results of our Study. Šalamon L, Morović-Vergles J (University Hospital Dubrava, Zagreb, Croatia)

16:45 -

16:55

0:10

O 12. Ambulatory Arterial Stiffness Index and Carotid Intima-media Thickness in Hypertensive Rheumatoid Patients: Experience in our Center. Mitrovic J (Division of Clinical Immunology and Rheumatology, Department of Internal Medicine, Dubrava University Hospital, University of Zagreb School of Medicine, Zagreb, Croatia)

16:55 -

17:05

0:10

O 13. Comparison of Clinical Characteristics of Diabetes Mellitus Patients with and without Scleredema Buschke Skin Disorder.. Varjú C (University of Pécs, Pécs, Hungary)

17:05 -

17:15

0:10

O 14. Arterial Stiffness in Systemic Lupus Erythematosus and Lupus Nefritis Patients. Schubertová M (Department of Internal Medicine III - Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc, University Hospital Olomouc, Olomouc, Czech Republic)

17:15 -

17:45

0:30

17:45 -

18:45

Satellite Symposium 1 - Immunology Update 2016 (MSD) Chair: Smolen J, Vencovský J

17:45 -

18:00

0:15

18:00 -

18:15

0:15

18:15 -

18:30

0:15

18:30 -

18:45

0:15

Break -foyer Lobby

Hall Zenit

The difficult choice - Comparing the Efficacy of Different Biological DMARDs, Smolen J, Vienna, Austria Use of Antirheumatic Drugs During Pregnancy and Lactation. Vencovsky J, Prague, Czech Republic Uveitis in Rheumatic Disorders and its Therapeutic Possibilities. Heissigerova J, Prague, Czech Republic Impact of AS on Work Disability and Influence of Anti TNF Therapy. Pavelka K, Prague, Czech Republic

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic 17:45 -

18:45

Satellite Symposium 2 - Right Treatment for the Right Patient - Making Successful Therapeutic Decisions Based on Different Patient Profiles (UCB) Chair: Kucharz EJ, Szekanecz Z.

Hall Nadir

17:45 -

18:00

0:15

18:00 -

18:15

0:15

News in the Diagnosis and Treatment of axSpA and nr-axSpA Patients. Pavelka K, Prague, Czech Republic Role of MRI in Early Diagnostic of nr-AxSpA Patients. Žlnay M, Piešťany, Slovakia

18:15 -

18:30

0:15

Early Diagnosis and Guideliness in Rheumatoid Arthritis. Kucharz EJ, Katowicz, Poland

18:30 -

18:45

0:15

Differences between Anti-TNFs - what do the H2H Studies Tell us? Psenak O, Salzburg, Austria

22:15

3:00

Networking

19:15

-

Congress foyer, Tycho, Kepler

Friday, 9th December 2016 8:30 -

10:00

General Session 3: Environmental Factors Chair: Szekanecz Z, Czirjak L

Hall Zenit

8:30 -

8:42

0:12 O 15. Influence of Environmental Factors on Comorbidities of Generalized Osteoarthritis. Kővári E, Bálint PV (National Institute of Rheumatology and Physiotherapy, Budapest, Hungary)

8:42 -

8:54

0:12 O 16. Chemicals and Scleroderma. Czirjak L (University of Pécs, Department of Rheumatology and Immunology, Pécs, Hungary)

8:54 -

9:06

9:06 -

9:18

0:12 O 17. Immune Mediated Necrotising Myopathy Associated with Statins. Vencovsky J (Institute of Rheumatology, Prague, Czech Republic) 0:12 O 18. Diet in Gout. Pálinkás M, Poór G (National Institute of Rheumatology and Physiotherapy, Budapest, Hungary)

9:18 -

9:30

0:12 O 19. The Salty Taste of Rheumatoid Artrhritis. Szekanecz Z (University of Debrecen, Hungary)

9:30 -

9:40

0:10 O 20. Exosomes Regulate the Human Osteoclastogenesis. Nagy G (Semmelweis University, Department of Rheumatology, Hungary)

9:40 -

9:50

0:10 O 21. Periodontal Status in Rheumatoid Arthritis and its Association with Smoking. Kovacs L et al (University of Szeged, Faculty of Medicine, Department of Rheumatology and Immunology, Hungary)

9:50 -

10:00

0:10 O 22. Analysis of ABCG2, SLC17A3, SLC22A11and SLC17A1 Genes in Patients with Primary Hyperuricemia and Gout. Petrů L (Institute of Rheumatology, Prague, Czech Republic)

10:00 -

10:30

0:30 Break - foyer Lobby

10:30 -

11:30

Satellite Symposium 3 - Decoding the Complex Interplay in PsA (Celgene) Chair: Štolfa J, Thaci D

Hall Zenit

10:30 -

10:50

0:20

Etiopathogenesis of PsA. Thaci D, Lübeck, Germany

10:50 -

11:10

0:20

Apremilast- a New Oral Therapy in PsA. Pavelka K, Prague, Czech Republic

11:10 -

11:30

0:20

Apremilast in European and GRAPPA Recommendations. Štolfa J, Šedová L, Prague, Czech Republic

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic 10:30 -

11:30

Satellite Symposium 4 - Treat to Target in SpA. (Novartis) Chair: Smolen J, Vencovský J

Hall Nadir

10:30 -

10:45

0:15 T2T in SpA. Smolen J, Vienna, Austria

10:45 -

11:00

0:15 Role of IL-17 in Pathophysiology of SpA. Vencovský J, Prague, Czech Republic

11:00 -

11:15

11:15 -

11:30

0:15 IL-17 Inhibitors (Cos) in the Context of the New EULAR PsA Guidelines. Praprotnik S, Slovenia 0:15 IL-17 Inhibitors (Cos) in the Context of the New EULAR AS Guidelines. Mann H, Prague, Czech Republic

11:30

-

11:35

0:05 Technical Break

11:35 -

13:05

General Session 4: Psoriatic Arthritis. Vasculitis Chair: Rovenský J, Tesař V

Hall Zenit

11:35 -

11:55

0:20 O 23. Disease Activity Assessment in Psoriatic Arthritis - Definition of Remission and other Outcomes. Smolen J (Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Austria)

11:55 -

12:15

12:15 -

12:35

0:20 O 24. Giant Cell Arteritis, Polymyalgia Rheumatica and Ocular Involvement. Rovenský J, Kozák I (National Institute of Rheumatic Diseases, Pieštany, Slovakia) 0:20 O 25. Treatment of ANCA-Associated Renal Vasculitis – beyond KDIGO Guidelines. Tesař V (Department of Nephrology, First Faculty of Medicine and General University Hospital, Prague, Czech Republic ) 0:10 O 26. ANCA Associated Vasculitides – clinical and Therapeutic Association. Lukáč J (Institute of Physiotherapy, Balneology and Medical Rehabilitation and National Institute of Rheumatic Diseases, Piešťany,Slovakia)

12:35 -

12:45

12:45 -

12:55

0:10 O 27. Diffuse Alveolar Hemorrhage: Acute, Life-threatening Vasculitis Syndrome. Bradna P (2nd Department of Internal Medicine,3rd Department of internal Medicine, Dept. of Immunology, Charles University Faculty of Med, University hospital, Hradec Kralove, Czech Republic)

12:55 -

13:05

0:10 O 28. Improved Clinical Outcomes and Workability in Spondyloarthritides During Real-life Administration of Adalimumab in Central and Eastern Europe. Szántó S (Department of Rheumatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary)

13:05 -

14:05

1:00

15:35

General Session 5: Malignancy and Rheumatic Diseases. Epidemiology

14:05

-

Boxed Lunch and Poster Session and Selected Poster Tour

foyer Lobby, Quadrant

Chair: Kucharz E, Wiland P.

Hall Zenit

14:05 -

14:25

0:20 O 29. Rhemuatic Diseases and Malignancy: from Bench to Bedside. Kucharz EJ (Department of Internal Medicine and Rheumatology, Medical University of Silesia, Katowice, Poland)

14:25 -

14:45

0:20 O 30. Paraneoplastic Syndromes in Rheumatology. Kotyla P (Department of Internal Medicine and Rheumatology, Medical University of Silesia, Katowice, Poland)

14:45 -

15:05

0:20 O 31. Prevalence and Clinical Characteristics of Rheumatoid Arthritis in Poland.

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic Batko B (Department of Rheumathology, J. Dietl Specialist Hospital, Krakow, Poland) presenting author - Wiland P 15:05 -

15:15

0:10 O 32. The Efficacy of Stopping Biologicals in Patients with SpA. Tłustochowicz M (Departament of Internal Diseases and Rheumatology, Military Institute of Medicine, Warszaw, Poland) presenting author – Raczkiewicz A

15:15 -

15:25

0:10 O 33. Neoplasma in Rheumatoid Arthritis patients - our Experience Gudelj Gračanin A (Division of Clinical Immunology, Allergology and Rheumatology, Department of Internal Medicine, Croatia)

15:25 -

15:35

0:10 O 34. Accumulation of S100A11 Protein in Rheumatoid Arthritis and its Correlation with Disease Activity and Inflammation. Andrés Cerezo L (Institute of Rheumatology, Prague, Czech Republic)

15:35 -

16:05

0:30 Break -foyer Lobby

16:05 -

17:05

Satellite Symposium 5 - A Different Journey is Possible for Patients with Spondyloarthritis (AbbVie) Hall Zenit Chair: Bálint P, Šenolt L

16:05 -

16:20

0:15

16:20 -

16:35

0:15

16:35 -

16:50

0:15

16:50

17:05

0:15

17:05

Satellite Symposium 6 (Biogen)

16:05

-

Ultrasound in the Evaluation of Enthesitis: Status and Perspectives. Balint P, Budapest, Hungary Role of Imaging in Progression Evaluation in Patients with Axial Spondyloarthritis. Grobelná K, Prague, Czech Republic Long-term Safety and Efficacy of Adalimumab for the Treatment of Ankylosing Spondylitis - Data from ATTRA Registry. Šenolt L, Prague, Czech Republic Translating PsA Guidelines into Practice: National Guidelines Update. Štolfa J, Prague, Czech Republic

Chair: Vencovský J, Kucharz EJ

Hall Nadir

16:05 -

16:25

0:20

Comorbidities in Patients with Rheumatoid Arthritis. Kucharz EJ, Katowicz, Poland

16:25 -

16:45

0:20

Current Situation of Biosimilars in Rheumatology. Vencovský J, Prague, Czech Republic

16:45 -

17:05

0:20

EULAR Recommendations and their Impact on Clinical Practice in Central Europe. Pavelka K, Prague, Czech Republic

17:05 -

17:10

0:05

Technical Break

17:10 -

18:55

General Session 6: Young Rheumatologists from CECR Countries Chair: Šenolt L, Nagy G

17:10 -

17:25

0:15

17:25 -

17:40

0:15

17:40 -

17:55

0:15

17:55 -

18:10

0:15

Hall Zenit

O 35. Neutrophil CARD9 Mediates Autoantibody-induced Autoimmune Diseases by Controlling Gene Expression Changes in vivo. Németh T (Department of Physiology, Semmelweis University School of Medicine, Budapest, Hungary) O 36. Increased Interest in Polymyalgia Rheumatic and Giant Cell Arteritis Leads to Increased Incidence. Milchert M (Pomeranian Medical University, Klinika Reumatologii, Szcecin, Poland) O 37. Antiprothrombin Antibodies in the Diagnosis of APS. Žigon P (University Medical Centre Ljubljana, Department of Rheumatology, Ljubljana, Slovenia) O 38. Cytokine Responses of T Cells, B Cells and Monocytes in Patients with Rheumatoid Arthritis: Effects of IL-35. Mravcová M (Institute of Experimental Endocrinology, Biomedical Research Centre, Slovak Academy of Sciences, Bratislava, Slovakia )

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic 18:10 -

18:25 -

18:25

18:40

0:15

O 39. The Role of Immunosenescene in Rheumatic Diseases.

0:15

Fessler J (Medizinische Universität, Klinische Abteilung für Rheumatologie und Immunologie, Graz, Austria) O 40. Cardiovascular Damage in Deceased Patients with Systhemic Lupus Erythematosus. Padjen I (University Hospital Centre Zagreb and University of Zagreb, School of Medicine, Croatia)

18:40 -

18:55

0:15

O 41. IL-35 in the Pathogenesis of Rheumatic Diseases. Filková M (Institute of Rheumatology, Department of Rheumatology of the 1st Faculty of Medicine, Charles University, Czech Republic)

19:00 19:45 -

Departure of Busses for Networking Event from the Hotel Clarion Reception 22:45

3:00

Networking Event

Villa Richter - Prague Castle

Saturday, 10th December 2016 8:30 -

8:30 -

10:00

8:50

General Session 7: Antiphospholipid syndrome Chair: Holc I, Ambrožič A 0:20

Hall Zenit

O 42. Antiphospholipid Syndrome: Clinical Manifestations and Treatment. Ambrožič A (Clinical Dept. of Rheumatology, UMC Ljubljana, Slovenija)

8:50 -

9:10

0:20

O 43. Venous Thrombosis and Antiphospholipid Antibodies. Perdan Pirkmajer A, Ambrožič A (Clinical Dept. of Rheumatology, UMC Ljubljana, Slovenija)

9:10 -

9:30

0:20

O 44. Antiphospholipid Antibodies, a Possible Etiologic Factor for Cerebrovascular Events in Younger Adult Patients. Gašperšič N (Clinical Dept.oOf Rheumatology, UMC Ljubljana, Slovenija)

9:30 -

9:45

0:15

O 45. Antiphospholipid Antibodies in Association to Adverse Pregnancy Outcome. Žigon P (Clinical Dept. of Rheumatology, UMC Ljubljana, Slovenija)

9:45 -

10:00

0:15

O 46. Pregnancy in Antiphospholipid Syndrome. Kovačič Grobelšek V, Holc I (Dept. of Rheumatology, Division of Internal Medicine, UMC Maribor, Slovenija) Break and Poster Session and Selected Poster Tour

10:00 -

11:00

1:00

11:00 -

12:20

General Session 8: Easy and Early Access Rheumatology Chair: Machold K, Nell V

foyer Lobby, Quadrant

Hall Zenit

11:00 -

11:20

0:20

O 47. Providing Timely Access to Rheumatology Services: Review of the International Approaches. Nell V (Klinikum Peterhof Baden, Austria)

11:20 -

11:40

0:20

O 48. The Austrian Central University Hospital Approach. Machold K(Medical University of Vienna, Austria)

11:40 -

12:00

0:20

O 49. The Austrian Office Based Cooperative Approach. Puchner R (Rheumatology Practice Wels, Austria)

12:00 -

12:10

0:10

O 50. Patients’ Dogma, Number of Swollen Joints and Physicians’ and Patients’ Age Predict Non-adherence to Medicines and Non-pharmacological Interventions in Rheumatoid Arthritis - a Mixed Methods Study Ritschl V (Institute of Outcomes Research, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Austria)

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic 12:10 -

12:20

0:10

O 51. Effectiveness of a Workplace-centered Initiative to Consuel Individuals with Musculosceletal Complaints (WORIMUCO): A prospective Pilot Cohort Study. Leiss H (MUV, Department of Rheumatology, Austria)

12:20 -

12:35

0:15

Summary and Close

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic

POSTER SESSIONS: Friday, December 9, from 13:00 - 14:00 hrs - Odd numbers Saturday, December 10, from 10:00 - 11:00 hrs - Even numbers

P1. BACK PAIN: AN UNCOMMON PRESENTATION OF GREAT VESSEL VASCULITIS. Águeda A, Centro Hospitalar Baixo Vouga E.P.E., Aveiro, Portugal P2. RITUXIMAB CAN INDUCE REMISSION IN A PATIENT WITH ANKYLOSING SPONDYLITIS WHO FAILED ANTI- TNF-α AGENT. Almetri Talal, Umm Al-Qura University, Mecca, Saudi Arabia P3. SUCCESSFUL RITUXIMAB TREATMENT OF MULTIPLE CARDIAC INVOLVEMENT IN GRANULOMATOSIS WITH POLYANGIITIS. Belobradkova Martina, Division Rheumatology, 2 nd Department of Internal Medicine – Gastroenterology, Charles University, Hradec Kralove, Czech Republic P4. SUSAC SYNDROME – A DIAGNOSTIC AND THERAPEUTIC DILEMMA. Bogna Grygiel-Górniak, Department of Rheumatology and Internal Medicine, Poznan University of Medical Sciences, Poland P5. DIFFERENCES IN THE INCIDENCE OF SELECTED CLINICAL AND IMMUNOLOGICAL SYMPTOMS MANIFESTATIONS USED IN THE SLICC CLASSIFICATION SYSTEM IN GROUPS OF LUPUS PATIENTS “WITH” OR “WITHOUT” THE PRESENCE OF ANTI-RO / SSA-60 ANTIBODIES. Dryglewska Magdalena, Department of Rheumatology and Connective Tissue Diseases, Medical University of Lublin, Poland P6. EFFICACY AND SAFETY OF BARICITINIB IN PATIENTS WITH RHEUMATOID ARTHRITIS AND INAPPROPRIATE RESPONSE TO CONVENTIONAL DISEASE-MODIFYING ANTI-RHEUMATIC DRUGS: 24-WEEK PHASE 3 RA-BUILD STUDY SUMMARY RESULTS. Presented by: Fialova A (non-author presenter) Eli Lilly CR s.r.o., Praha, Czech Republic P7. PREMATURE SENESCENCE OF NAÏVE T-CELLS IN SJÖGREN’S SYNDROME AND SYSTEMIC LUPUS ERYTHEMATOSUS. Fasching Patrizia, Medical University of Graz, Austria P8. A RANDOMIZED, DOUBLE-BLIND, ACTIVE- AND PLACEBO-CONTROLLED PHASE 3 STUDY OF EFFICACY AND SAFETY OF IXEKIZUMAB, ADALIMUMAB, AND PLACEBO THERAPY IN PATIENTS NAÏVE TO BIOLOGIC DISEASE MODIFYING ANTIRHEUMATIC DRUGS WITH ACTIVE PSORIATIC ARTHRITIS. Presented by: Irtó I (non-author presenter), Lilly Hungária, Budapest, Hungary P9. BARICITINIB, METHOTREXATE, OR BARICITINIB PLUS METHOTREXATE IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS WHO HAD RECEIVED LIMITED OR NO TREATMENT WITH DISEASE-MODIFYING ANTI-RHEUMATIC DRUGS: PHASE 3 TRIAL RESULTS. Presented by: Fialova A (non-author presenter) Eli Lilly CR s.r.o., Praha, Czech Republic P10. COMPARISON OF THE EFFECT OF ANTI-TNF THERAPY ON MEASURES OF PHYSICAL FUNCTION AND HEALTH RELATED QUALITY OF LIFE IN PATIENTS WITH RHEUMATOID ARTHRITIS AND ANKYLOSING SPONDYLITIS – RESULTS FROM THE CZECH BIOLOGIC REGISTRY ATTRA. Forejtova Sarka, Institute of Rheumatology and First Faculty of Medicine , Charles University in Prague, P11. INCOMPLETE ATYPICAL FEMORAL FRACTURE COMPLICATING LONG-TERM USE OF BISPHOSPHONATES - CASE REPORT.

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic Franeková Lenka, Internal Clinic - Outpatient Department of Rheumatology and Osteology, Military University Hospital, Prague, Czech Republic P12. PANNICULITIS IN AN OPIOID-ADDICTED PATIENT. Fryc Justyna, Medical University of Bialystok, Poland P13. PATIENTS WITH AXIAL SPONDYLOARTHRITIS: BASELINE CLINICAL CHARACTERISTIC AND SUBSETS DIFFERENCES IN SINGLE CENTRE COHORT. Grobelná Kristýna, Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic P14. ANNUAL CHANGES OF SERUM SURFACTANT PROTEIN D IN PATIENTS WITH SYSTEMIC SCLEROSIS. Grosicka Anida, Medical University of Silesia, Department of Internal Medicine and Rheumatology, Katowice, Poland P15. POLYSEROSITIS AS A PARANEOPLASTIC SYNDROME IN THYROID GLAND CANCER. Henyšova Veronika, Institute of Rheumatology and Clinic of Rheumatology 1st Faculty of Medicine of Charles University, Prague, Czech Republic P16. CHRONIC DAMAGE IN SYSTEMIC LUPUS ERYTHEMATOSUS IS ASSOCIATED WITH INCREASED SERUM LEVELS OF IL6, IL8 AND CCL2/MCP1. Horák Pavel, 3rd Department of Internal Medicine, University Hospital of Olomouc, Faculty of Medicine and Dentistry, Palacký University of Olomouc, Olomouc, Czech Republic P17. B CELL ACTIVATING FACTOR (BAFF) IN SERUM AND SYSTEMIC LUPUS ERYTHEMATOSUS DISEASE ACTIVITY USING SLEDAI-2K SCORING SYSTEM (EAST BOHEMIAN REGIONAL STUDY). Hrncir Zbynek, 2nd Department of Internal Medicine, Charles University Hospital, Hradec Králové, Czech Republic P18. HIGH BASELINE EXPRESSION OF CIRCULATING MICRORNA-342-3P PREDICTS POOR RESPONSE TO THERAPY IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS . Hruskova Veronika, Institute of Rheumatology and Dpt. of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic P19. THE EFFECT OF BIOLOGICAL TREATMENT ON SERUM TENASCIN-C IN PATIENTS WITH LONGLASTING RHEUMATOID ARTHRITIS . Hulejová Hana, Institute of Rheumatology and Department of Rheumatology, 1 st Faculty of Medicine, Charles University, Prague, Czech Republic P20. SERUM CALPROTECTIN DISTINGUISHES SUBCLINICAL DISEASE ACTIVITY FROM ULTRASOUND-DEFINED REMISSION IN PATIENTS WITH RHEUMATOID ARTHRITIS IN CLINICAL REMISSION. Hurnakova Jana, Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Czech Republic P21. THE CLINICAL IMPROVEMENT AND BIOMARKER CHANGES AFTER INTENSIVE EXERCISE PROGRAMME FOR NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS AND FOR ANKYLOSING SPONDYLITIS. . Hušáková Markéta, Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Czech Republic P22. VITAMIN D IN RHEUMATOID ARTHRITIS: ITS RELATIONSHIP WITH AUTOANTIBODIES AND LABORATORY DISEASE ACTIVITY MARKERS. Iwaszkiewicz Cezary, Department of Rheumatology and Osteoporosis, Jozef Strus Municipal Hospital in Poznan, Poznań, Poland

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic

P23. PREGNANCY OUTCOMES IN ADULT JUVENILE IDIOPATHIC ARTHRITIS PATIENTS TREATED WITH BIOLOGIC AGENTS. Jarosova Katerina, Institute of Rheumatology, Prague, Czech Republic P24. SERUM OSTEOPONTIN LEVEL IN PATIENTS WITH RHEUMATOID ARTHRITIS . Kopec-Medrek M., Department of Internal Medicine and Rheumatology, Poland P25. POLYMYOSITIS AS A MASK OF AMYOTROPHIC LATERAL SCLEROSIS – DIAGNOSTIC DIFFICULTIES. Koszarny Arkadiusz, Medical University of Lublin, Poland P26. SATISFACTION AND DISSATISFACTION OF PATIENTS WITH RHEUMATIC DISEASES RECEIVING BIOLOGICS. Kotulska Anna, Medical University of Silesia, Katowice, Poland P27. THE COMPARISON OF THE EFFICACY AND SAFETY OF PHENYRAMIDOL AND PHENYRAMIDOL + DICLOFENAC IN ACUTE SPINAL PAINFUL MUSCLE SPASM- AN OPEN STUDY. Koyuncu Halil, IU,Cerrahpasa Medical Faculty,Physical Medicine and Rehabilitation Department,Istanbul, Turkey P28. IMPAIRED MOUTH STATE IN PATIENTS WITH SYSTEMIC SCLEROSIS CORRELATED WITH SKIN INVOLVEMENT. Kramza Justyna, Department of Internal Medicine and Rheumatology, Medical University of Silesia, Katowice, Poland P29. ON THE 150TH BIRTH ANNIVERSARY OF DR. EDMUND FAUSTYN BIERNACKI AND HIS FORGOTTEN CONTRIBUTION TO THE DISCOVERY OF ERYTHROCYTE SEDIMENTATION RATE. Kucharz Eugene J, Department of Internal Medicine and Rheumatology, Medical University of Silesia, Katowice, Poland P30. THE INCIDENCE OF HYPERSENSITIVITY TO NSAIDS IN THE GROUP OF PATIENTS WITH MUSCULOSKELETAL DISORDERS. Lewandowska-Polak Anna, Medical University of Lodz, Poland P31. TUMOR-INDUCED HYPOPHOSPHATEMIC OSTEOMALACIA: A CASE REPORT. Lokočová Eva, 3rd Department of Internal medicine-NRE, University Hospital and Faculty of Medicine Palacký University, Olomouc, Czech Republic P32. OCCURRENCE MALIGNANCIES IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH A TNF-BLOCKING AGENTS – OBSERVATION IN SLOVAK COHORT. Lukáčová Olga, Národný ústav reumatických chorôb, Piešťany, Slovakia P33. CLINICAL PRESENTATION OF PATIENTS WITH THE PRESENCE OF ANTISYNTHETASE AUTOANTIBODIES. Masiak Anna, Clinic of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdansk, Poland P34. APPLICATION OF TREAT TO TARGET PRINCIPLES IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS IN ROUTINE CLINICAL PRACTICE IN CENTRAL - EASTERN EUROPE. Codreanu C, "Dr. Ion Stoia" Center for Rheumatic Diseases, University of Medicine and Pharmacy "Carol Davila" Bucharest, Romania P35. ANALYSIS OF NON-TYPHOID SALMONELLA INFECTIONS IN THE CZECH POPULATION OF SLE PATIENTS. A RETROSPECTIVE, 20 YEARS STUDY.

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic Olejárová Marta, Institute of Rheumatology, Prague and Clinic of Rheumatology, Ist Medical Faculty, Charles University, Prague, Czech Republic P36. ASSOCIATION OF HLA-DRB1 ALLELES WITH MIXED CONNECTIVE TISSUE DISEASE (MCTD). Paradowska-Gorycka Agnieszka, Department of Biochemistry and Molecular Biology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland P37. GENETIC VARIANTS IN IL-12B AND IL-27 IN THE PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS. Paradowska-Gorycka Agnieszka, Department of Biochemistry and Molecular Biology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland P38. IL-12B GENE POLYMORPHISMS AND IL-12 P70 SERUM LEVEL AMONG POLISH PATIENTS WITH RHEUMATOID ARTHRITIS. Paradowska-Gorycka Agnieszka, Department of Biochemistry and Molecular Biology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland P39. ASSOCIATION BETWEEN THE STAT3 POLYMORPHISMS, VEGF SERUM LEVEL AND RHEUMATOID ARTHRITIS IN POLISH POPULATION. Paradowska-Gorycka Agnieszka, Department of Biochemistry and Molecular Biology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland P40. FLT1 GENETIC VARIATION AFFECTS THE CLINICAL RHEUMATOID ARTHRITIS PHENOTYPE. Paradowska-Gorycka Agnieszka, Department of Biochemistry and Molecular Biology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland P41. DETECTION OF POLYMORPHISMS IN TPMT GENE BEFORE STARTING AZATHIOPRINE THERAPY. Pavelcova Katerina, Institute of Rheumatology, Prague, Czech Republic P42. MiR-451 DIFFERENTIATES PATIENTS WITH CLINICALLY SUSPECT ARTHRALGIA FROM HEALTHY CONTROLS. Prajzlerová Klára, Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic P43. INTERMETATARSAL BURSITIS AS A MANIFESTATION OF RHEUMATOID ARTHRITIS – CASE PRESENTATION. Reihl Mirna, General Hospital Vukovar, Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital Centre Zagreb , Croatia P44. PAEDIATRIC RHEUMATOLOGIST AND ORPHAN DISEASE – A STORY WITHOUT HAPPY ENDING. Roszkiewicz Justyna, Department of Paediatric Rheumatology, Medical University of Lodz, Poland P45. REFERRAL OF EARLY ARTHRITIS PATIENTS TO A RHEUMATOLOGY CLINIC - A MODEL DEVELOPED IN A CROATIAN TERTIARY CENTRE. Rukavina Krešimir, University Hospital Centre Zagreb, Croatia P46. RELATIONSHIP BETWEEN RHEUMATOID ARTHRITIS DISEASE ACTIVITY ASSESSED WITH THE US7 SCORE AND QUALITY OF LIFE MEASURED WITH QUESTIONNAIRES (HAQ, EQ-5D, WPAI). Skácelová Martina, 3rd Department of Internal Medicine, University Hospital of Olomouc, Faculty of Medicine and Dentistry, Palacký University of Olomouc P47. THE RELATIONSHIP BETWEEN INFLAMMATORY PARAMETERS AND CLINICAL MANIFESTATIONS OF EARLY SPONDYLOARTHRITIS.

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic Skoczynska Marta, Department and Clinic of Rheumatology and Internal Medicine, Wroclaw Medical University, Poland P48. INTIMA MEDIA THICKNESS AND ATHEROSCLEROTIC PLAQUES AS A MARKERS OF SUBCLINICAL ATHEROSCLEROSIS AND CARDIOVASCULAR MANIFESTATION IN SLE PATIENTS. Smržová Andrea, 3rd Department Of Internal Medicine – Nephrology, Rheumatology And Endocrinology, Faculty Hospital and University Palacky Olomouc, Czech Republic P49. THE INFLUENCE OF CAFFEINE CONSUMPTION ON THE THERAPEUTIC EFFECTS OF METHOTREXATE IN THE TREATMENT OF RHEUMATOID ARTHRITIS IN PATIENTS WITH DIFFERENT ADORA2A GENOTYPES. Soukup Tomáš, Charles University, Faculty of Medicine and University Hospital in Hradec Kralove, 2 nd Department of Internal Medicine-Gastroenterology, Division of Rheumatology, Czech Republic P50. DECREASED BODY FAT, LEAN BODY MASS AND BONE MINERAL DENSITY IN SCLERODERMA PATIENTS ARE ASSOCIATED WITH DISEASE ACTIVITY AND PHYSICAL ACTIVITY. Śpiritović Maja, Institute of Rheumatology, Dept. of Rheumatology, 1 st Faculty of Medicine and Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic P51. INCREASED BODY FAT BUT DECREASED LEAN BODY MASS AND BONE MINERAL DENSITY IN MYOSITIS PATIENTS ARE ASSOCIATED WITH DISEASE DURATION, INFLAMMATORY STATUS, SKELETAL MUSCLE INVOLVEMENT AND PHYSICAL ACTIVITY. Śpiritović Maja, Institute of Rheumatology, Dept. of Rheumatology, 1st Faculty of Medicine and Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic P52. PROGRESSION OF PAIN AND ULTRASOUND DETECTED SYNOVITIS IN PATIENTS WITH EROSIVE HAND OSTEOARTHRITIS OVER ONE YEAR. Šléglová Olga, Institute of Rheumatology, Prague, Czech Republic P53. ELEVATED HEAT SHOCK PROTEIN 90 IN MUSCLE TISSUE AND PLASMA IN IDIOPATHIC INFLAMMATORY MYOPATHIES IS ASSOCIATED WITH SKELETAL MUSCLE INVOLVEMENT AND DISEASE ACTIVITY. Štorkánová Hana, Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic P54. S100A PROTEINS EFFECTIVELY DISCRIMINATE SLE PATIENTS FROM HEALTHY CONTROLS, BUT THEIR LEVELS DO NOT ASSOCIATE WITH MEASURES OF DISEASE ACTIVITY. Šumová Barbora, Institute of Rheumatology and Department of Rheumatology, 1 st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic P55. BARICITINIB VERSUS PLACEBO OR ADALIMUMAB IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS AND AN INADEQUATE RESPONSE TO BACKGROUND METHOTREXATE THERAPY: RESULTS OF A PHASE 3 STUDY. Presented by: Irtó I (non-author presenter), Lilly Hungária, Budapest, Hungary P56. PREGNANCY OUTCOMES IN A COHORT OF WOMEN WITH ANTIPHOSPHOLIPID SYNDROME. 20- YEARS LONG- TERM OBSERVATION. Tegzová Dana, Institute of Rheumatology, Prague, Czech Republic P57. IMPACT OF HIF-1Α GENE POLYMORPHISMS AND ITS PROTEIN LEVEL ON RA ACTIVITY. Paradowska-Gorycka Agnieszka, Department of Biochemistry and Molecular Biology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland P58. THE LEVELS OF SOLUBLE CD163 IN PATIENTS WITH ANKYLOSING SPONDYLITIS..

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11th Central European Congress of Rheumatology, 8th – 10th December 2016, Prague, Czech Republic Tošovský Marián, 2nd Department of Internal Medicine, Charles University Hospital, Hradec Králové, Czech Republic P59. ATHEROSCLEROSIS, HYPERTENSION, ADULT TYPE II DIABETES MELLITUS AND ISOLATED AMYLOIDOSIS LOCALIZED TO THE ISLETS OF LANGERHANS – A POSTMORTEM CLINICOPATHOLOGIC STATISTICAL STUDY OF 161 RHEUMATOID ARTHRITIS PATIENTS. Apáthy Ágnes, Department of Rheumatology – St. Margaret Clinic Budapest, Hungary P60. EVALUATION OF THE PAIN LEVEL IN PATIENTS WITH GOUT. Vatseba Mariana, Ivano-Frankivsk state Medical Universuty, Ivano-Franlivsk, Ukraine P61. EVALUATION OF THE LEFT VENTRICULAR FUNCTION IN PATIENTS WITH SYSTEMIC SCLEROSIS AND MIXED CONNECTIVE TISSUE DISEASE. Vymětal Jiří, 3rd Department of Internal Medicine - nephrology, rheumatology and endocrinology, University Hospital in Olomouc, Czech Republic P62. EFFICACY AND SAFETY OF BARICITINIB IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS AND INADEQUATE RESPONSE TO TUMOUR NECROSIS FACTOR INHIBITORS: 24WEEK PHASE 3 RA-BEACON STUDY RESULTS. Presented by: Irtó I (non-author presenter), Lilly Hungária, Budapest, Hungary P63. THE RELATIONSHIP BETWEEN SYNOVITIS QUANTIFIED BY AN ULTRASOUND 7-JOINT INFLAMMATION SCORE AND PHYSICAL DISABILITY IN RHEUMATOID ARTHRITIS – A COHORT STUDY. Závada Jakub, Institute of Rheumatology, Prague, Czech Republic P64. DIAGNOSTICS OF VASCULITIS OF THE SMALL INTESTINE IN GRANULOMATOSIS WITH POLYANGIITIS Kopecká Iveta, Department of Pathology and Anatomy, Trnava University Hospital, Slovakia P 65. CLINICAL PRESENTATION OF PATIENTS WITH MDA-5-ASSOCIATED DERMATOMYOSITIS. Masiak A, Wojteczek A, Czuszyńska Z, Wierzba K, Gałecka K, Zdrojewski Z Clinic of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdansk, Poland

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