EFNS BUDAPEST 2011 PRELIMINARY PROGRAMME PRELIMINARY PROGRAMME AND CALL FOR ABSTRACTS

PRELIMINARY PROGRAMME EFNS BUDAPEST 2011 PRELIMINARY PROGRAMME AND CALL FOR ABSTRACTS 15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIET...
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PRELIMINARY PROGRAMME

EFNS BUDAPEST 2011 PRELIMINARY PROGRAMME AND CALL FOR ABSTRACTS 15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011 ABSTRACT DEADLINE: MARCH 15, 2011

www.efns.org/efns2011

HOST

Organised in co-operation with the Hungarian Society of Neurology and Psychiatry

Co-sponsored by the European Section of the Movement Disorder Society (MDS-ES)

Co-sponsored by the European Headache Federation (EHF)

Co-sponsored by the World Federation of Neurology (WFN)

XXX CO-SPONSORSHIP

XXX

HOST Organised in co-operation with the Hungarian Society of Neurological Society

CO-SPONSORSHIP Co-sponsored by the European Section of the Movement Disorder Society (MDS-ES)

Co-sponsored by the European Headache Federation (EHF)

Co-sponsored by the World Federation of Neurology (WFN)

DATES TO REMEMBER ABSTRACT SUBMISSION DEADLINE: March 15, 2011 EARLY REGISTRATION DEADLINE: June 15, 2011

ORGANISERS AND SECRETARIAT

1-3 rue de Chantepoulet, PO Box 1726 CH-1211 Geneva 1, Switzerland Tel: +41 22 908 04 88, Fax: +41 22 906 91 40 E-mail: [email protected] Website: www.kenes.com

PRELIMINARY PROGRAMME

CO-SPONSORSHIP

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

PRELIMINARY PROGRAMME

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BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

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TABLE OF CONTENTS

About Budapest ......................................................................................................................................................................................................................... 6 Welcome message ................................................................................................................................................................................................................. 7 Committees

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Preliminary timetable .................................................................................................................................................................................................... 11

Registration

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General information

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TABLE OF CONTENTS

Social events ............................................................................................................................................................................................................................... 12 13 14

Bursaries ......................................................................................................................................................................................................................................... 17 Call for abstracts .................................................................................................................................................................................................................. 18 Abstract topics ........................................................................................................................................................................................................................ 19

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Tournament for Young Neurologists Investigator Award Approval for CME

Hotel accommodation

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15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Poster instructions ............................................................................................................................................................................................................ 21

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PRELIMINARY SCIENTIFIC PROGRAMME Teaching courses ................................................................................................................................................................................................................. 30 Main topics

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EFNS Lecture on Clinical Neurology

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57 69

Focused workshops .......................................................................................................................................................................................................... 71 Special sessions

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BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

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ABOUT BUDAPEST CO-SPONSORSHIP

BUDAPEST

ABOUT BUDAPEST

As the largest city of Hungary, Budapest serves as the country’s principal political, cultural, commercial and industrial center and acts as an important hub in Central Europe. Budapest, the capital of Hungary was created out of the unification of the separate historic towns of Buda, Pest and Óbuda in 1873. Whilst the area had been inhabited from early times, it was from this date that the city’s expansion into a world capital really began. Flowing north to south through the centre of the city is the mighty River Danube. Buda and Óbuda, comprising roughly a third of the total, are situated mainly in the hills to the west, with commercial Pest on the plains to the east.

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Regarded as one of the most beautiful cities in Europe, Budapest is home to the largest synagogue in Europe (Great Synagogue), the largest medicinal bath in Europe (Széchenyi Medicinal Bath) and the third largest Parliament building in the world, once the largest in the world. The third largest church in Europe (Esztergom Basilica) and the second largest Baroque castle in the world (Gödöllő) are in the vicinity. Its World Heritage Sites include the banks of the Danube, the Buda Castle Quarter, Andrássy Avenue, and the Millennium Underground railway, the first on the European continent. Budapest possesses a rich and fascinating history, as well as a vibrant cultural heritage. Recognizing the unique value of its traditions, it has managed to maintain its magic and charm, and is known as the Queen of the Danube. It has also been called the City of Spas, as there are a dozen thermal baths complexes served by over a hundred natural thermal springs. Despite spectacular development, Budapest has preserved its old world charm. It is the city where the pleasing harmony of different architectural styles and superb structures, the cafes, baths, the food and culture, combined with legendary hospitality blend into an unforgettable experience for visitors.

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WELCOME MESSAGE

WELCOME

WELCOME MESSAGE

Welcome to the 15th EFNS Congress in Budapest 10 – 15 September 2011. Our programme includes all major neurological topics and combines up-to date review lectures by world’s leading experts with free presentations of research results, presented for the first time. We expect between 4,000 and 5,000 neurologists to gather in Budapest, and around 2,000 abstracts having been submitted. These coming days will be very busy for European and non-European neurologists, and will make a difference for our professional work.

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

This is a general neurology congress, covering neurology in the broadest sense. Specialists will receive latest news not only in their field, but also get an update on other topics, necessary for daily patient practice. A congress like this is an excellent way to help keeping all subdisciplines together and at the same time promote research and research input across subfields. Our congress combines specialist education including teaching courses, overviews, satellite symposia and the exhibition with free oral presentations, posters, and focused workshops. The EFNS congress is an optimal meeting place for young and established neurologists. We are coming from all European countries, and also from the rest of the world. It is a special pleasure to see how the EFNS congress attracts so many active participants also from outside Europe. My appeal to all of you is that you approach colleagues from all the countries during your days in Budapest and that you discuss and exchange information. Stroll along in the poster area, at the exhibition or during the breaks, and you will have an excellent opportunity to exchange ideas and views with colleagues and potential professional friends. Budapest and Hungary is an ideal meeting place. The city is near the geographical centre of Europe and it has a strong medical and neurological history. Budapest combines old and modern history and has played a major role in the European development during the last decades. For those of you not knowing Budapest, I can promise you a charming and active central European city and for those who already know and love the city, this EFNS congress is an opportunity to renew your relationship with Budapest.

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PRELIMINARY PROGRAMME

WELCOME MESSAGE CO-SPONSORSHIP

WELCOME MESSAGE

The EFNS congress has as its main aim the promotion of general neurology. However, in addition to being general neurologists, we also have our special interests; regarding patient groups, treatment modalities, often linked to research or developmental projects. The congress attracts not only neurologists but also specialists in neighbouring fields with whom the EFNS has formal cooperation agreements. Information about new developments in the industry represents an important element during the EFNS congress, giving updated knowledge about pharmaceutical drugs acting on the nervous system, on technology and equipment used for diagnosis and therapy, and on relevant literature. Satellite symposia, often focusing on new treatment options, are always gathering a big audience.

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

The Congress Programme Committee has put together a scientific programme that should be of broad interest to everyone working within neurology. We are grateful for all the good suggestions that we have received; from the EFNS Scientist Panels, national EFNS member societies, and interested neurologists. The free presentations represent a backbone of our congress, and we really hope that all of you will continue to submit your most interesting new scientific results to the EFNS congress. We are all responsible for shaping and developing a joint platform for our professional activity, a meeting place to discuss how to develop treatment and diagnosis of neurological disease, but also how to organise and join forces to obtain optimal results. The aim of the EFNS is to facilitate such activity and to co-operate broadly with all other parties. The 15th EFNS Congress in Budapest 2011 will show you our intentions. I welcome you all to Budapest.

NILS ERIK GILHUS CHAIR, CONGRESS PROGRAMME COMMITTEE

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COMMITTEES

PRESIDENT

Richard Hughes, UK

PAST PRESIDENT

Jacques L. De Reuck, Belgium

VICE PRESIDENTS

Marianne De Visser, The Netherlands Sergei Illarioshkin, Russia Gian Luigi Lenzi, Italy

SECRETARY GENERAL

Detlef Kömpf, Germany

TREASURER

David B. Vodušek, Slovenia

MEMBERS AT LARGE

Michael Barnes, UK Panagiota Davaki, Greece

COMMITTEES

EFNS MANAGEMENT COMMITTEE

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

CONGRESS PROGRAMME COMMITTEE Nils Erik Gilhus, Norway, CHAIRPERSON László Vécsei, Hungary, VICE-CHAIRPERSON Michael Brainin, Austria, SCIENTIFIC COMMITTEE László Csiba, Hungary Marianne De Visser, The Netherlands Hans-Christoph Diener, Germany, EHF Alla Guekht, Russia Sámuel Komoly, Hungary Jean-Marc Léger, France, TEACHING COURSE SUB-COMMITTEE Werner Poewe, Austria, MDS-ES Hilkka Soininen, Finland

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

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PRELIMINARY PROGRAMME

COMMITTEES CO-SPONSORSHIP

LOCAL ARRANGEMENTS COMMITTEE László Vécsei,

CHAIRPERSON

Dániel Bereczki László Csiba Sámuel Komoly Zoltán Nagy Imre Szirmai

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

COMMITTEES

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János Tajti

TEACHING COURSE SUB-COMMITTEE Jean-Marc Léger, France, CHAIRPERSON Christian Confavreux, France Hans-Christoph Diener, Germany, EHF Antonio Gil-Nagel, Spain Hans-Peter Hartung, Germany Detlef Kömpf, Germany Isabel Illa, Spain Hubert Kwiecinski, Poland Bo Norrving, Sweden Werner Poewe, Germany, MDS-ES Philip Scheltens, The Netherlands Jean Schoenen, Belgium Liliya Zvyagina, Ukraine

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

PRELIMINARY TIMETABLE

SUNDAY, SEPTEMBER 11, 2011

MONDAY, SEPTEMBER 12, 2011

TUESDAY, SEPTEMBER 13, 2012

08.30 – 20.00 Registration

TC | 07.30 – 09.00 Teaching Course 20

TC | 07.30 – 09.00 Teaching Courses 21&22

TC | 07.30 – 09.00 Teaching Courses 24&25

TC | 09.30 – 11.00 FREE Teaching Course

MT | 08.30 – 10.30 Main Topics

MT | 08.30 – 10.30 Main Topics

MT | 08.30 – 10.30 Main Topics

TC | 11.30 – 16.30 Teaching Courses 1–19

10.30 – 11.00 Coffee Break, Exhibition and Poster Visit

10.30 – 11.00 Coffee Break, Exhibition and Poster Visit

10.30 – 11.00 Coffee Break, Exhibition

SpS | 16.30 – 17.30 Special Session

ShC & TYN | 11.00 – 12.30 Short communications Tournament for Young Neurologists I

ShC & TYN | 11.00 – 12.30 Short communications Tournament for Young Neurologists II

ShC & LBN | 11.00 – 12.00 Short communications Late breaking news

SaS | 17.00 – 18.30 Satellite Symposia

12.30 – 14.30 Lunch break, Exhibition and Poster Visit

12.30 – 14.30 Lunch break, Exhibition and Poster Visit

12.00 – 13.00 EFNS Lecture on Clinical Neurology

SE | 19.00 Opening ceremony followed by Welcome reception

SaS | 13.00 – 14.30 Satellite symposia

SaS | 13.00 – 14.30 Satellite symposia

13.00 – 14.30 Lunch break, Exhibition

14.30 – 16.00 Poster session

14.30 – 16.00 Poster session

SaS | 13.00 – 14.30 Satellite symposia

SpS | 14.30 – 17.00 Special Sessions

SpS | 15.00 – 17.00 Special Sessions

SpS | 14.30 – 16.30 Special Session

FW & TC | 15.30 – 17.00 Focused workshops

FW & TC | 15.30 – 17.00 Focused workshops FREE Teaching Course 23

FW | 15.00 – 16.30 Focused workshops

17.00 – 17.30 Coffee Break, Exhibition and Poster Visit

17.00 – 17.30 Coffee Break, Exhibition and Poster Visit

SE | 16.45 Closing session Farewell reception

SaS | 17.30 – 19.00 Satellite symposia

SaS | 17.30 – 19.00 Satellite symposia

20.30 Scientific Gulyás dinner: Neuroimmunology – a walk through the woods

SE | Evening Social event at the Budapest Market Hall

KEY:

TC | Teaching Courses (additional fee required)

TYN | Tournament for Young Neurologists

SaS | Satellite Symposia

ShC | Short Communications

FW | Focused Workshops

LBN | Late Breaking News

SpS | Special Sessions

SE

MT | Main Topics

| Social Events

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

PRELIMINARY TIMETABLE

Friday, September 09, 2011 13.00 – 19.00 Registration

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SOCIAL EVENTS CO-SPONSORSHIP

SATURDAY, SEPTEMBER 10, 2011 19.00 h

Opening ceremony at Hungexpo PROGRAMME: Welcoming words Challenges in neurology Richard Hughes, EFNS President

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SOCIAL EVENTS

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László Vécsei Vice-chairperson Congress Programme Committee Nils Erik Gilhus Chairperson Congress Programme Committee Entertainment Followed by a Welcome Reception

MONDAY, SEPTEMBER 12, 2011 Evening

Special Social Event at the Budapest Market Hall Join us for a true Hungarian celebration in the great Market Hall of Budapest. Walk around the numerous stalls, dine and drink the best of Hungarian rich food and wine. (additional fee of € 10) Details will be available on the congress website: www.efns.org/efns2011

TUESDAY, SEPTEMBER 13, 2011 16.45 h

Closing Session Investigator Award Uschi Tschabitscher Prize for Young Neurologists Presentation of EFNS 2012 – Stockholm, Sweden Followed by Farewell Reception

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

REGISTRATION

from June 16, 2011

€ 495

€ 565

on site (valid from September 2, 2011)

€ 595

Non-members

€ 575

€ 605

€ 635

Residents and students *

€ 295

€ 315

€ 325

Teaching courses and Hands-on courses **

€ 15

€ 15

€ 20

€ 50

History of Neurology Tour

€ 40

Additional ticket for opening session and welcome reception

€ 50

Ticket for Social Event **

€ 10

€ 10

€ 15

* Student registration form must be accompanied by a letter from the head of department confirming their status and/or a valid student card. EFNS members from Eastern European countries, which are not members of the EU may apply for residents‘ registration fee. ** Limited space – early booking is recommended

Please register via the congress website www.efns.org/efns2011 Fees for participants and residents include: q 1BSUJDJQBUJPOJOTDJFOUJǸDTFTTJPOT q 7JTJUPGUIFFYIJCJUJPO q ŁFQSJOUFENBUFSJBMPGUIF$POHSFTT q "DFSUJǸDBUFPGBUUFOEBODF q 0QFOJOHTFTTJPOBOEXFMDPNFSFDFQUJPO q ŁSFFMVODIFT q $PǴFFEVSJOHCSFBLT q 1VCMJDUSBOTQPSUBUJPOUJDLFU CANCELLATION POLICY Refund of registration fees will be as follows: Postmarked until and including June 15, 2011 – 100% refund (minus € 50 handling fee) Postmarked from June 16, 2011 – 50% refund No refund on cancellations after August 10, 2011.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Scientific Gulyás dinner: Neuroimmunology: a walk through the woods **

REGISTRATION

Members of European national neurological societies, individual EFNS members

until June 15, 2011

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GENERAL INFORMATION CO-SPONSORSHIP

LOCATION Budapest Hungexpo Website: www.hungexpo.hu

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

GENERAL INFORMATION

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CLIMATE The average September temperature in Budapest is between 12° and 22°C.

CLOTHING Informal for all occasions; please bring an umbrella and walking shoes. In the evening a jacket is recommended.

EXHIBITION An extensive exhibition will be held concurrently with the Congress. For information:

15th EFNS Congress

1-3 rue de Chantepoulet, PO Box 1726 CH-1211 Geneva 1, Switzerland Tel: +41 22 908 04 88, Fax: +41 22 906 91 40 E-mail: [email protected] Website: www.efns.org/efns2011

LANGUAGE English is the official language of the Congress.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

GENERAL INFORMATION

OFFICIAL LETTER OF INVITATION

PERSONAL INSURANCE It is recommended that all participants take out a personal travel and health insurance for their trip.

TRAVEL INFORMATION

There are two terminals: Terminal One is by low-cost airlines and Terminal Two is divided into two, with Terminal 2A the departure and arrival point for flights of Malév Hungarian Airlines and Terminal 2B hosting all international carriers‘ flights, including some of the budget airlines. By train: Budapest has three main international railway stations: Eastern (Keleti), Western (Nyugati) and Southern (Déli). More than fifty trains a day provide direct links between Budapest and 25 other European capital cities. Trains to Vienna run every three hours, 7 times a day. There is also a popular network of Inter City trains, linking Budapest with the main Hungarian towns. By river: There is a daily scheduled hydrofoil service on the Danube, linking Vienna, Bratislava and Budapest, between early April and early November. Voyage duration: from Vienna to Budapest 5 hours, from Budapest to Vienna 6 hours. After the hydrofoil trip, which takes you through scenic areas of Hungary (such as the beautiful Danube Bend), you arrive in the heart of Budapest. Information about Mahart PassNave Ltd. services is available on their website: www.mahartpassnave.hu

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

By air: You can visit Budapest from an array of low-cost airlines, or the national carrier, Malév. Budapest (Ferihegy) International Airport is sixteen kilometers south-east of downtown Budapest.

GENERAL INFORMATION

Official letters of invitation designed to help overcome administrative difficulties in certain countries will be posted on the Congress website for participants’ use. It must be understood that such letters do not represent a commitment on the part of the Organizing Committee or Congress to provide any financial assistance.

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GENERAL INFORMATION CO-SPONSORSHIP

WEBSITE www.efns.org/efns2011 The Congress website will be updated on a regular basis and will give the latest details on the scientific programme and other Congress information.

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

GENERAL INFORMATION

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BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

BURSARIES

The EFNS is pleased to inform that it is also possible for young colleagues from EFNS Associate member societies (Algeria, Egypt, Lebanon, Libya, Jordan, Morocco, Tunisia and Syria) to apply for bursaries. In addition, the EFNS invites African neurologists from Sub-Saharan countries belonging to the HINARI band 1 list of countries as established by WHO http://www.who.int/hinari/eligibility/en/ to apply for a bursary.

This information should be sent via the online application form which will be available on the Congress website: www.efns.org/efns2011. Applications for bursaries will only be considered if submitted by the time of abstract submission deadline. Deadline for submission of abstracts and applications for bursaries is March 15, 2011. Bursary recipients will be selected on the basis of abstract evaluation by the Congress Programme Committee. Applicants who have been granted a bursary will be informed well before elapse of the early registration fee deadline.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Applications must be accompanied by a copy of your passport showing your date of birth, as well as your abstract submission confirmation number.

BURSARIES

The EFNS offers up to 200 bursaries consisting of free registration to the congress and four nights hotel accommodation to European neurologists not older than 35 years (born 1975 and later) who are not yet in a permanent position and whose abstracts have been accepted. 20 of these bursaries will be awarded for papers on movement disorders through a grant funded jointly by the EFNS and the Movement Disorder Society – European Section (MDS-ES). The bursary applications for papers on movement disorders will be reviewed by MDS-ES and EFNS.

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CALL FOR ABSTRACTS CO-SPONSORSHIP

CALL FOR ABSTRACTS Participants are requested to submit an abstract to the Secretariat NO LATER THAN MARCH 15, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

CALL FOR ABSTRACTS

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together with the registration form and fees. The Congress Programme Committee welcomes the submission of abstracts on any neurological topic. The committee will decide the form of presentation: oral or poster. If you do not want to give a platform presentation, please select “poster only” when submitting your abstract. If you have no special preference, please select “either” when submitting your abstract. Authors will be notified of the method of presentation, which will be decided by the Congress Programme Committee. Accepted abstracts will be published in a supplement to the European Journal of Neurology provided that the Congress Programme Committee considers them suitable for publication. ABSTRACTS OF INVITED SPEAKERS Invited speakers will receive a special weblink for submission of abstracts, and are requested NOT to use the regular abstract submission form on the website. METHOD OF SUBMISSION Abstracts must be submitted via the internet: www.efns.org/efns2011. If you have no access to the internet, please contact the Secretariat. GUIDELINES FOR SUBMISSION 1

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The abstract should be as informative as possible: (a) state specific object of study (c) summarise results obtained (b) state method used if pertinent (d) state conclusions reached Abstracts should be structured. Standard abbreviations may be used. Inclusion in the Scientific Programme and Abstract Volume is dependent on payment of registration fees. Facilities for computerized projection will be available for all congress sessions (teaching courses, main topics, short communications, focused workshops, and special sessions). Video projection (European VHS/PAL system, low band) and overhead projection will be provided only if ordered by July 10, 2011. Abstracts should be submitted in good English. Abstract length should not exceed 250 words. Abstracts that were published at previous events/in other publications, i.e. encore abstracts, cannot be accepted. Important note: A maximum of 3 abstracts per presenting author may be submitted.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

CALL FOR ABSTRACTS / TOPICS

Abstracts should be submitted using the internet site of the congress. For further instructions, please visit: www.efns.org/efns2011

ABSTRACT TOPICS Ageing and dementia Autonomic nervous system Cerebrovascular diseases Child neurology / developmental neurology Clinical neurophysiology Cognitive neurology / neuropsychology Critical care Education in neurology Epilepsy Ethics in neurology Headache and pain History of neurology Infection and AIDS Motor neurone diseases Movement disorders MS and related disorders Muscle and neuromuscular junction disease Neuroepidemiology Neurogenetics Neuroimaging Neuroimmunology Neurological manifestations of systemic diseases Neurology and arts Neuro-oncology Neuroophthalmology / neurootology Neurotoxicology /occupational neurology Neurotraumatology Peripheral nerve disorders Rehabilitation Sleep disorders Spinal cord and root disorders

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

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CALL FOR ABSTRACTS

Faxed abstracts are not acceptable.

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CALL FOR ABSTRACTS CO-SPONSORSHIP

LATE BREAKING NEWS Abstracts must be submitted BEFORE APRIL 15, 2011.

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

CALL FOR ABSTRACTS

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If data are not yet available at submission deadline, authors should present background and design of the study in their abstract and confirm that the results and conclusions of their investigations will be ready for presentation at the 15th EFNS Congress. Please send your confirmation about this in writing by e-mail, fax or regular mail when submitting your abstract to: 15th EFNS Congress

1-3 rue de Chantepoulet, PO Box 1726 CH-1211 Geneva 1, Switzerland Tel: +41 22 908 04 88, Fax: +41 22 906 91 40 E-mail: [email protected] Website: www.efns.org/efns2011

As in the nature of the wording, late breaking abstracts are NOT regular abstracts, but important contributions that cannot wait to be presented at the next EFNS congress. Late abstract submissions will not be accepted. No case reports will be accepted. Only a limited number of high-standard abstracts can be retained for one oral session on the last day of the congress. These abstracts must be exclusively related to results of new treatments of neurological disorders, which have not been presented at any other national or international congress. Interesting abstracts, not retained for the oral session, can only be presented as poster without publication.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

ONGOING CLINICAL TRIALS A special poster session on ongoing clinical trials might be held provided that a sufficient number of good abstracts meeting this particular format and its criteria will be received and selected. If you wish to present your study at this session, please add “ongoing clinical trial” after the title. This special poster session is mainly aiming at raising awareness about new studies and to allow possible new centres to be involved.

POSTER INSTRUCTIONS Posters must be mounted on the day for which they are accepted between 08.00 and 09.00 in the morning and remain on display until the end of sessions on that day. The dimensions of the poster boards are 90 cm wide x 120 cm high. Material for mounting posters will be provided in the poster area.

Detailed instructions for preparing posters will be available on the Congress website: www.efns.org/efns2011 in due course.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Authors are requested to be present at their posters during the poster session for which their poster has been scheduled. At that time, poster chairpersons will walk around and discuss posters selected by the Congress Programme Committee for discussion.

CALL FOR ABSTRACTS / POSTER INSTRUCTIONS

CALL FOR ABSTRACTS

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TOURNAMENT CO-SPONSORSHIP

TOURNAMENT – USCHI TSCHABITSCHER PRIZE FOR YOUNG NEUROLOGISTS For the 9th time, a tournament for young neurologists will take place at an EFNS Congress. The tournament will be carried out in two groups, one on clinical related research, and one on basic neurological science.

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

TOURNAMENT

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PARTICIPATION: Neurologists in training not older than 35 years (born 1975 and later) are entitled to participate. When submitting an abstract of which they are the first author, candidates must state that they wish to participate in the tournament and select the group (clinical/basic). They must send by mail a confirmation written by the head of the candidate’s department stating the age of the candidate, his/her training and that the abstract is the personal work of the candidate. SELECTION OF CANDIDATES: The Congress Programme Committee will select 6 candidates for each tournament group on the basis of the contents of the abstracts submitted. The clinical subjects should be received from authors who all work in Europe and thus carry out their projects in Europe. For the basic science session, clinical relevance will be weighted. The Congress Programme Committee reserves the right to assign in which session the presentation will take place. FINANCIAL SUPPORT: Candidates selected for the tournament will receive a bursary consisting of free registration to the Congress, up to four nights hotel accommodation, and a travel grant. PRESENTATION: Each selected candidate is allotted 10 minutes for presentation of his/her paper plus five minutes for discussion with the jury. JURY: Members of the Congress Programme, the Scientific and the Teaching Course Committees. EVALUATION: Candidates will be judged not only on the scientific value of the work presented, but also on the quality of the oral presentation and the way the candidate responds to the questions of the jury.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

TOURNAMENT

TOURNAMENT

PRIZE: The winner of each group will receive the Uschi Tschabitscher Prize for Young Neurologists consisting of: Free registration at the 16th EFNS Congress in Stockholm Sweden, September 8 – 11, 2012, up to four nights hotel accommodation, a travel grant, as well as € 1,000. The prize is not transferable and participation in the 16th Congress of the EFNS will not be paid off in cash.

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

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INVESTIGATOR AWARD / APPROVAL FOR CME CO-SPONSORSHIP

EFNS INVESTIGATOR AWARD FOR FREE PRESENTATIONS

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

INVESTIGATOR AWARD

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All free presentations (short communications, posters) selected for presentation at the 2011 Congress of the EFNS will automatically take part in the selection of an Investigator Award. The EFNS Scientist Panels (currently 24, in all fields of neurology) will be responsible for the evaluation process (independent from other awards and the programme organisation). The award for each selected presentation will be € 500, a diploma, and the winners will be announced in the European Journal of Neurology and the EFNS Newsletter. The award will be given to the first author who needs to be the person to present the work at the congress. A presentation can be the winner of one only scientist panel investigator award. Notification about the Investigator Award will be sent within four weeks after the congress.

APPROVAL FOR CME The 15th EFNS Congress is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS): http://www.uems.be. The 15th EFNS Congress (Sunday, Monday, Tuesday) is designated for a maximum of 18 hours of European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity. The Teaching Courses are each designated for 2 hours of external CME credits. EACCME credits are recognized by the American Medical Association towards the Physician‘s Recognition Award (PRA). To convert EACCME credit to AMA PRA category 1 credit, contact the AMA. This congress has been approved for CME by the Austrian Chamber of Physicians. This congress has been approved for CPD by the Royal College of Physicians of London.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

HOTEL ACCOMMODATION

Kenes International is the official travel agent for the 15th Congress of the European Federation of Neurological Societies, and will be offering specially reduced rates for hotel accommodation.

BOOKING In order to benefit from the special rates, please book your hotel accommodation through the congress website: www.efns.org/efns2011

For hotel reservation made by a sponsoring company, the participant will receive the hotel confirmation from the sponsoring company directly. For block bookings (10 rooms and up) companies are requested to send their request by fax or e-mail to Kenes International to Tami Vidra: [email protected]. Different payment and cancellation policies will apply.

PAYMENT Full payment for accommodation, provided by Kenes International is payable (less deposit) before your arrival in Budapest. Kenes International accepts Travellers’ cheques and Euro cheques (in the currency of the issuing country), Visa, Master Card, Diners Club and American Express credit cards. Please note, 3 weeks prior to arrival in Budapest, your credit card will be automatically charged for the balance of your hotel accommodation. Participants who paid with a bank transfer or cheque, need to send this balance to Kenes International. Full prepayment is required for all hotel accommodations.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

We strongly advise all participants to reserve their hotel accommodation as soon as possible. Reservations will only be confirmed if credit card details are fully supplied; alternatively, please forward a deposit of 1 night payment per room in order to guarantee your accommodation. Each participant will receive an individual confirmation, indicating the name and address of the hotel. The booking will be final upon receipt of the corresponding deposit.

HOTEL ACCOMMODATION

REGISTRATION DEPARTMENT 1-3 rue de Chantepoulet, P.O. Box 1726 CH-1211 Geneva 1, Switzerland Tel: +41 22 908 04 88, Fax: +41 22 906 91 40 E-mail: [email protected]

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PRELIMINARY PROGRAMME

HOTEL ACCOMMODATION CO-SPONSORSHIP

Hotel accommodation payment instructions: Hotel accommodation charges can be paid only in Euro. Payment made in other currencies will be converted into Euro according to the exchange rate on the day of receipt of payment.

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

HOTEL ACCOMMODATION

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Hotel accommodation charges can be paid by the following methods: By credit card: Visa, Master Card, Diners Club and American Express. Your monthly credit card statement will indicate payment made to “Kenes International”. By bank transfer: Please make drafts payable to “EFNS 2011” Credit Suisse Bank, Geneva Branch, Switzerland. Clearing Number: 4835, Account Number: 693980-51-2 IBAN: CH52 0483 5069 3980 5100 2 Swift code: CRESCHZZ 12A

CANCELLATION OF ACCOMMODATION q 1SJPSUPEBZTCFGPSFBSSJWBM VQUP  – Full refund less handling fee of 35 Euro. q #FUXFFOrEBZTQSJPSUPBSSJWBM VQUP  – 1 night cancellation charge. q 'SPNr/PSFGVOE In the event of non-arrival, the hotel will automatically release the reservation, and the payment will be non-refundable. All changes or cancellations have to be made in writing to Kenes International. Please do not contact the hotel directly.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

HOTEL ACCOMMODATION

EARLY DEPARTURE FEE

IMPORTANT NOTE Kenes International, and their agents, will not be responsible for and will be exempted from all liability in respect of any loss, damage, injury, accident, delay or inconvenience to any person, or his/her luggage or any other property for any reason whatsoever, for any tourist services provided. Personal travel and health insurance is recommended.

HOTEL ACCOMMODATION

Guests will be charged for checking out prior to the departure date confirmed at check-in. Official check-in time for hotels is 15:00 h and check out is 12:00 h.

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

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GENERAL INFORMATION CO-SPONSORSHIP

EFNS Educational Grants 2011

The EFNS is happy to offer the following grants to young neurologists:

EFNS DEPARTMENT-DEPARTMENT CO-OPERATION PROGRAMME 2011 80 grants each amounting to a maximum of € 1,800.– in order to make it possible to stay at a foreign department for 6 weeks. APPLICATION DEADLINE: 30 November 2010

FELLOWSHIP 2011 GENERAL INFORMATION

8 scientific grants & 4 educational grants amounting to a maximum of € 2,000.– per month DURATION: up to 12 months APPLICATION DEADLINE: 31 December 2010

EFNS ACADEMY – MAY 12 - 15, 2011 This annual meeting offers lectures and workshops for up to 120 young neurologists. Participants pay for their travel only. APPLICATION DEADLINE: 31 January 2011

CME ARTICLES Each month a CME article is published in the European Journal of Neurology and on the EFNS website. Answer 5 article-related questions correctly and receive a certificate recommending one hour of CME. APPLICATION: Please register on the EFNS website for free-of-charge access.

All application forms can be downloaded from www.efns.org EFNS – Excellence in Neurology since 1991

WWW.EFNS.ORG

PRELIMINARY PROGRAMME

PRELIMINARY SCIENTIFIC PROGRAMME

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

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PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 09.30 – 11.00

FREE TEACHING COURSE: HOW DO I EXAMINE ... ? CONVENORS:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

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Daniel Bereczki, BUDAPEST, HUNGARY Richard Hughes, LONDON, UK

…mononeuropathies? Richard Hughes, London, UK ...dystonia? Marie Vidailhet, Paris, FRANCE …a first seizure? Paul Boon, Ghent, BELGIUM

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

TEACHING COURSES

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 11.30 – 13.30

TEACHING COURSES

COURSE DIRECTORS:

Alfredo Berardelli, ROME, ITALY Werner Poewe, INNSBRUCK, AUSTRIA

Phenomenology and approach to patients with gait disorders Bastiaan Bloem, Nijmegen, THE NETHERLANDS Recent advances in dystonia: aetiology and pathophysiology Alfredo Berardelli, Rome, ITALY

What a general neurologist should know about deep brain stimulation in movement disorders Marie Vidailhet, Paris, FRANCE

After attending this course you will: q6OEFSTUBOEUIFDMJOJDBMQSFTFOUBUJPOBOEEJǴFSFOUJBMEJBHOPTUJDXPSLVQPGQBUJFOUT with different disorders of gait q3FDPHOJTFUIFDMJOJDBMTQFDUSVNPGOPOFQJMFQUJDNZPDMPOJDNPWFNFOUEJTPSEFST q#FBCMFUPNBLFSBUJPOBMEFDJTJPOTPOUJNJOHBOEUSFBUNFOUPQUJPOTXIFOJOJUJBUJOH drug therapy for Parkinson’s disease q6OEFSTUBOEUIFQSJODJQMFTBOEDMJOJDBMJOEJDBUJPOTPGEFFQCSBJOTUJNVMBUJPO procedures to treat tremor disorders, dystonia and Parkinson’s disease

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

When and how to begin treatment of Parkinson’s disease Wolfgang Oertel, Marburg, GERMANY

SATURDAY, SEPTEMBER 10, 2011

TEACHING COURSE 1 MOVEMENT DISORDERS – BASIC CLINICAL KNOWLEDGE

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PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 14.30 – 16.30

TEACHING COURSES

TEACHING COURSE 2: MOVEMENT DISORDERS – ADVANCED COURSE DIRECTORS:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

32

Marie Vidailhet, PARIS, FRANCE László Vécsei, SZEGED, HUNGARY

Sexual dysfunction in movement disorders: why don’t we talk about it? Clare Fowler, London, UK Parkinson’s disease look-alike – what is it? Joaquim Ferreira, Lisbon, PORTUGAL Sleep-wake regulation in parkinsonian syndromes; from pathophysiology to clinical phenomenology Birgit Högl, Innsbruck, AUSTRIA Jumps and starts – from myoclonus to startle syndromes José Obeso, Pamplona, SPAIN

After attending this course you will: q#FBCMFUPUBLFBOBQQSPQSJBUFIJTUPSZ QMBOBODJMMBSZUFTUTBOEUSFBUNFOU for sexual dysfunction in degenerative parkinsonism q3FDPHOJTFUIFDMJOJDBMGFBUVSFTPGTZNQUPNBUJDGPSNTPGQBSLJOTPOJTNBOECF able to plan differential diagnostic procedures q3FDPHOJTFUIFDMJOJDBMTQFDUSVNPGTMFFQXBLFEZTSFHVMBUJPOJO1BSLJOTPOnTEJTFBTF and understand the role of REM sleep behaviour disorder as a potential marker of pre-clinical PD q6OEFSTUBOESFDFOUBEWBODFTJOUIFFUJPQBUIPHFOFTJTPGQSJNBSZEZTUPOJB

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 11.30 – 13.30

TEACHING COURSES

TEACHING COURSE 3: STROKE: NEUROLOGICAL COMPLICATIONS IN THE LONG TERM. BASIC CLINICAL KNOWLEDGE SATURDAY, SEPTEMBER 10, 2011

COURSE DIRECTORS:

Didier Leys, LILLE, FRANCE Bo Norrving, LUND, SWEDEN

Post-stroke fatigue Gillian Mead, Edinburgh, UK Long-term cognitive effects of stroke Didier Leys, Lille, FRANCE

Central post-stroke pain – still underdiagnosed and undertreated? Bo Norrving, Lund, SWEDEN

Many new data have accrued on the long term consequences after stroke. The topics covered by this Teaching Course often occur long after the stroke at a time when follow ups by neurologists have ceased and patients have been transferred to primary care. Nevertheless these complications represent diagnostic and therapeutic challenges that call for strengthened involvement of neurologists in the management of stroke patients in the long term. The course will provide an update on core competences in this field.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Spasticity after stroke David Werring, London, UK

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PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 14.30 – 16.30

TEACHING COURSES

TEACHING COURSE 4: ADVANCES IN STROKE IN THE YOUNG COURSE DIRECTORS:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

34

Martin Brown, LONDON, UK Martin Dichgans, MUNICH, GERMANY

Intracranial occlusive diseases – still enigmatic? Martin Brown, London, UK What causes intracerebral haemorrhage in the young? Charlotte Cordonnier, Lille, FRANCE The changing spectrum of genetic causes of stroke in the young Martin Dichgans, Munich, GERMANY The long-term prognosis of stroke in the young – is it really favourable? Turgut Tatlisumak, Helsinki, FINLAND

There has been substantial progress in the field of stroke in the young. Investigations and therapies of intracranial arterial disease in the young (moya-moya and similar syndromes) have advanced. More is known about the causes of intracerebral haemorrhage in the young which now should guide the diagnostic workup. The genetic field has advanced considerably and we now have a much fuller picture on e.g. CADASIL and Fabry’s disease. The first large scale long term prognostic studies have recently been reported and will be followed by more data available in the near future. The course will review the latest advances in stroke in the young. Case vignettes will be presented and ample time will be given for discussion.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 11.30 – 13.30

TEACHING COURSES

COURSE DIRECTOR:

Hans-Peter Hartung, DÜSSELDORF, GERMANY

Pathogenesis of MS Burkhard Becher, Zurich, SWITZERLAND Epidemiology and course of MS Christian Confavreux, Lyon, FRANCE

The management of MS Hans-Peter Hartung, Düsseldorf, GERMANY

This course aims at providing fundamental knowledge on MS. The course will start with a review of current thoughts on aetiology and pathogenesis, followed by an overview of the geographic peculiarities, triggers, disease course and prognostic factors. A critical assessment of the diagnostic process will be presented and finally a guide to current management strategies for the disease will be given.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

The diagnosis of MS David Miller, London, UK

SATURDAY, SEPTEMBER 10, 2011

TEACHING COURSE 5: MULTIPLE SCLEROSIS – BASIC CLINICAL KNOWLEDGE

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PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 14.30 – 16.30

TEACHING COURSES

TEACHING COURSE 6: MANAGEMENT OF MULTIPLE SCLEROSIS BY EARLY AND PERSISTENT IMMUNOTHERAPY - ADVANCED

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

36

COURSE DIRECTOR:

Hans Lassmann, VIENNA, AUSTRIA

Tissue destruction in early phases of MS Hans Lassmann, Vienna, AUSTRIA Rationales for early onset of immunotherapy Xavier Montalban, Barcelona, SPAIN Key determinants for therapeutic success – neutralizing antibodies Per Soelberg Sørensen, Copenhagen, DENMARK Outlook on future therapies Ralf Gold, Bochum, GERMANY

To provide rationales for early tissue destruction in MS lesions, the need and the success of early start of immunotherapy, critical determinants for success of immunotherapy with particular impact on neutralizing therapeutic antibodies, and outlook on future therapies which are in the developmental pipeline. Renowned international key speakers will present adapted and mutually synergistic topics.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 11.30 – 13.30

TEACHING COURSES

COURSE DIRECTOR:

Philip Scheltens, AMSTERDAM, THE NETHERLANDS

Introduction and overview Philip Scheltens, Amsterdam, THE NETHERLANDS The clinical diagnosis of dementia Martin Rossor, London, UK

Neuroimaging examinations: CT, MRI, SPECT, PET Leonardo Pantoni, Florence, ITALY

At the end of the course the general neurologist will know all that is needed to make a clinical diagnosis of dementia, to differentiate subtypes and make use of and interpret correctly the various sorts of ancillary investigations.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Laboratory examinations including CSF Jakub Hort, Prague, CZECH REPUBLIC

SATURDAY, SEPTEMBER 10, 2011

TEACHING COURSE 7: LUIGI AMADUCCI TEACHING COURSE ON DEMENTIA – BASIC CLINICAL KNOWLEDGE

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PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 14.30 – 16.30

TEACHING COURSES

TEACHING COURSE 8: LUIGI AMADUCCI TEACHING COURSE ON DEMENTIA – ADVANCED

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

38

COURSE DIRECTOR:

Yolande Pijnenburg, AMSTERDAM, THE NETHERLANDS

Introduction, incidence and prevalence, clinical tools Yolande Pijnenburg, Amsterdam, THE NETHERLANDS The frontotemporal dementias Florence Pasquier, Lille, FRANCE Young onset AD: a different form of Alzheimer’s? Jonathan Rohrer, London, UK Recent advances in genetics of early onset dementia Kristel Sleegers, Antwerp, BELGIUM

At the end of the course the general neurologist will know how important the field of early onset dementia has become. Recent advances in clinical, genetic and diagnostic modalities will be presented to bring the participants up to date.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 11.30 – 13.30

TEACHING COURSES

COURSE DIRECTOR:

Federico Vigevano, ROME, ITALY

Treatment of status epilepticus Eugen Trinka, Innsbruck, AUSTRIA Initiation and discontinuation of antiepileptic drugs Antonio Gil-Nagel, Madrid, SPAIN

Combination therapy Martin Brodie, Glasgow, UK

Managing epilepsy requires diverse clinical skills, ranging from decisions on when and how to start treatment with antiepileptic drugs, selection of the drug that better fits the patient, choosing appropriate combination therapies, and treating acute lifethreatening situations, such as status epilepticus. The aim of this course is to review the current knowledge on such diverse issues, and provide information to guide the clinician in each step of epilepsy treatment.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Therapy according to seizure and syndrome classification Federico Vigevano, Rome, ITALY

SATURDAY, SEPTEMBER 10, 2011

TEACHING COURSE 9: TREATMENT OF EPILEPSY – BASIC CLINICAL KNOWLEDGE

39

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 14.30 – 16.30

TEACHING COURSES

TEACHING COURSE 10: ADVANCED ASPECTS OF EPILEPSY FOR THE CLINICIAN

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

40

COURSE DIRECTOR:

Philippe Ryvlin, LYON, FRANCE

Cognitive problems in epilepsy Christoph Helmstaedter, Bonn, GERMANY Brain imaging in diagnosis and localization Hermann Stefan, Erlangen, GERMANY Relevant genetic testing in epilepsy José M. Serratosa, Madrid, SPAIN Surgery in temporal lobe epilepsy Philippe Ryvlin, Lyon, FRANCE

New challenges in the diagnosis and treatment of epilepsy slowly have been introduced in clinical practice. Among them cognitive problems in patients with epilepsy are known to be a major cause of concern to patients and their families, requiring early identification and appropriate treatment. Traditional brain imaging has shown to be insufficient in the diagnosis of epilepsy, and physicians now have the responsibility to obtain the right brain MRI sequences and look for epileptogenic lesions, such as cortical dysplasias and hippocampal sclerosis. A number of genetic markers have been identified in paediatric epilepsy syndromes, most of these patients reach adult life and remain undiagnosed overtime. Finally, surgical treatment of epilepsy has evolved, with new recording techniques available and the possibility to improve patients that were previously considered poor candidates. This course will review these topics and provide clues for their management.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 11.30 – 13.30

TEACHING COURSES

COURSE DIRECTOR:

Rigmor Jensen, GLOSTRUP, DENMARK

Epidemiology and diagnosis of chronic headache Zaza Katsarava, Essen, GERMANY Mechanisms and neurobiology Rigmor Jensen, Glostrup, DENMARK

Treatment of chronic trigeminal autonomic cephalalgias (TAC’s) and secondary headaches Dominique Valade, Paris, FRANCE

The objectives of this teaching course are: To raise interest in and awareness of a major health problem To identify and diagnose chronic headache To give an update on the pathophysiological mechanisms of chronic headache To provide the participants with the present state of the art management of chronic headache

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Treatment of chronic primary headaches (migraine, tension-type headache) Fabio Antonaci, Pavia, ITALY

SATURDAY, SEPTEMBER 10, 2011

TEACHING COURSE 11: CHRONIC HEADACHE: UPDATE ON EPIDEMIOLOGY, MECHANISMS AND TREATMENT

41

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 14.30 – 16.30

TEACHING COURSES

TEACHING COURSE 12: NEUROIMAGING OF NEURODEGENERATIVE DISEASES

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

42

COURSE DIRECTOR:

Massimo Filippi, MILAN, ITALY

Alzheimer’s disease Massimo Filippi, Milan, ITALY Non-Alzheimer dementias Peter Nestor, Cambridge, UK Movement disorders Vladimir Kostic, Belgrade, SERBIA Motor neurone diseases Jan Kassubek, Ulm, GERMANY

Due to their high sensitivity, relative non-invasiveness, and major technical advances, neuroimaging techniques (mainly MRI and PET) have become, in the past decades, an irreplaceable way of quantifying the extent of CNS injury, defining the nature of the different pathological substrates of the various CNS affections, assessing the functional changes following tissue damage. More recently also, the potential of these techniques to monitor the effect of treatment has been shown. This teaching course provides a complete and up-to-date review of the role of neuroimaging techniques in the diagnosis, prognosis and understanding of pathophysiology of the major neurodegenerative CNS conditions, including Alzheimer’s disease and other dementias, movement disorders, and motor neurone diseases.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 11.30 – 13.30

TEACHING COURSES

TEACHING COURSE 13: NEUROMUSCULAR DISEASES I

Myopathies with extraocular muscle involvement David Hilton-Jones, Oxford, UK Inflammatory myopathies: a clinical and therapeutical update Marianne de Visser, Amsterdam, THE NETHERLANDS

New therapies for previously non tractable neuromuscular diseases Volker Straub, Newcastle upon Tyne, UK

This course will familiarize neurologists with both basic as well as practical aspects of different neuromuscular disorders through the particular view of experts in each of the selected fields. The course will emphasize the new and most important clinical and therapeutic aspects of muscle diseases, ALS and peripheral neuropathies. The aim of the course is to generate awareness about the enormous changes in this field, through a comprehensive description of the recent advances in diagnosis, pathogenesis and issues related to therapy.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Statins and myopathy Tiziana Mongini, Torino, ITALY

SATURDAY, SEPTEMBER 10, 2011

COURSE DIRECTORS:

David Hilton-Jones, OXFORD, UK Marianne De Visser, AMSTERDAM, THE NETHERLANDS

43

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 14.30 – 16.30

TEACHING COURSES

TEACHING COURSE 14: NEUROMUSCULAR DISEASES II COURSE DIRECTORS:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

44

Albert Ludolph, ULM, GERMANY Jean-Michel Vallat, LIMOGES, FRANCE

ALS: upper motor neurones, lower motor neurones and/or both Wim Robberecht, Leuven, BELGIUM ALS and FTD – a new or old relationship? Albert Ludolph, Ulm, GERMANY Classification of CMT syndromes Peter De Jonghe, Antwerp, BELGIUM CMT linked to mitofusine mutations Jean-Michel Vallat, Limoges, FRANCE

This course will familiarize neurologists with both basic as well as practical aspects of different neuromuscular disorders through the particular view of experts in each of the selected fields. The course will emphasize the new and most important clinical and therapeutic aspects of muscle diseases, ALS and peripheral neuropathies. The aim of the course is to generate awareness about the enormous changes in this field, through a comprehensive description of the recent advances in diagnosis, pathogenesis and issues related to therapy.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 11.30 – 13.30

TEACHING COURSES

TEACHING COURSE 15: NEUROSONOLOGY COURSE DIRECTOR:

SATURDAY, SEPTEMBER 10, 2011

David Russell, OSLO, NORWAY

Carotid and vertebral diseases Claudio Baracchini, Padova, ITALY Vessel wall diseases E. Bernd Ringelstein, Würzburg, GERMANY

Therapeutic ultrasound in CNS diseases Carlos Molina, Barcelona, SPAIN

Stroke is an increasing health care and social burden in our society and the neurosonological methods play an important role in stroke prevention, diagnosis and therapy. Owing to the development over the past few years, the ultrasonic diagnostic methods proved their entitlement not only in the diagnosis of vascular diseases but in therapy, monitoring and rehabilitation as well. This course will provide a survey of the development of neurosonological methods.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Cerebral monitoring with ultrasound David Russell, Oslo, NORWAY

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PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 14.30 – 16.30

TEACHING COURSES

TEACHING COURSE 16: NEURO-OPHTHALMOLOGY COURSE DIRECTOR:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

46

Natan Bornstein, TEL AVIV, ISRAEL

The retinal vessels as a mirror of the brain vessels Natan Bornstein, Tel Aviv, ISRAEL Episodic loss of vision: diagnostic challenges Anat Kessler, Kfar Saba, ISRAEL Oculomotor disturbances in stroke Detlef Kömpf, Lübeck, GERMANY Cortical aspects of visual disturbances Masud Husain, London, UK

The eyes talk and therefore can give us information about brain pathologies. The course will discuss various aspects of the relationship between the eyes and neurological conditions. We will discuss retinal vessels pathology as a mirror of the brain and visual disturbances syndromes due to cortical brain damage. Oculomotor disturbances and episodic loss of vision as a diagnostic challenge will also be discussed.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 11.30 – 13.30

TEACHING COURSES

TEACHING COURSE 17: METABOLIC NEUROGENETIC DISORDERS

The genetic counselling session and background on the molecular tests in the laboratory Jean-Marc Burgunder, Bern, SWITZERLAND Clinical clues to guide for the search of a genetic neurometabolic disorder Antonio Federico, Siena, ITALY

In-depth analysis of selected neurometabolic disorders, which are important to be recognised for management Frédéric Sedel, Paris, FRANCE

The pace of discovery in genetic disorders has been tremendous during the last decade, with consequences now reaching everyday neurological practice, including patients requesting genetic testing. This course will provide basic knowledge for the general neurologist about practical management steps he can take at the start of investigations when a genetic disorder is suspected in an adult patient. Emphasis will be put on neurometabolic genetic disorders. After a general introduction on the basis of the investigations a survey will be offered on which clinical features should lead the neurologist to think about a neurometabolic genetic disorder. Finally, selected examples relevant for their frequency or the importance of their management will be presented.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

In-depth analysis of neurometabolic disorders presenting as movement disorders Timothy Lynch, Dublin, IRELAND

SATURDAY, SEPTEMBER 10, 2011

COURSE DIRECTOR:

Jean-Marc Burgunder, BERN, SWITZERLAND

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PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 14.30 – 16.30

TEACHING COURSES

TEACHING COURSE 18: MY MOST DIFFICULT CASES COURSE DIRECTORS:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

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László Csiba, DEBRECEN, HUNGARY Michael Brainin, KREMS, AUSTRIA SPEAKERS:

László Csiba, DEBRECEN, HUNGARY Michael Brainin, KREMS, AUSTRIA Pierre Amarenco, PARIS, FRANCE Alfredo Berardelli, ROME, ITALY The recently developed diagnostic methods and evidence based therapeutic guidelines are useful techniques in the routine practice of neurologists. Unfortunately, in some patients the clinical symptoms are unusual/atypical and the laboratory or imaging findings misleading. Schematic use of diagnostic algorithms may lead to false diagnosis and therapy. Precise case history, careful general and neurological investigations and trained medical intelligence were/are and will always be indispensable parts of correct diagnosis. This is true after all for neurological diseases that might have an unusual onset or course and sudden worsening (MS, stroke, infective diseases of CNS, tumours, etc.). The aim of this course is to discuss some difficult neurological cases (misleading case history, laboratory or imaging) treated by experienced neurologists. The speakers will demonstrate the ambiguities of their most difficult cases, present the diagnostic and therapeutic alternatives and specify the key(s) to correct diagnosis and/or therapy in order to help those colleagues who may have similar patients in their future careers.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 11.30 – 13.30

TEACHING COURSES

TEACHING COURSE 19: THERAPY IN NEUROLOGY

Brain metastases Riccardo Soffietti, Turin, ITALY Guillain-Barré syndrome Pieter van Doorn, Rotterdam, THE NETHERLANDS

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Restless legs syndrome Yves Dauvilliers, Montpellier, FRANCE

SATURDAY, SEPTEMBER 10, 2011

COURSE DIRECTORS:

Jean-Marc Léger, PARIS, FRANCE Richard Hughes, LONDON, UK

Early multiple sclerosis Alastair Compston, Cambridge, UK

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

49

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 CO-SPONSORSHIP 07.30 – 09.00

TEACHING COURSES

TEACHING COURSE 20: HANDS-ON COURSE ON CLINICAL NEUROPHYSIOLOGY – NERVE CONDUCTION

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SUNDAY, SEPTEMBER 11, 2011

50

COURSE DIRECTORS:

Pierre Bouche, PARIS, FRANCE

Nerve conduction study is one of the essential steps in the electrophysiological diagnosis in peripheral nerve disorders. There are routine tests for usual pathologies such as carpal tunnel syndrome, ulnar nerve lesions at elbow or peroneal nerve at fibular head or for diffuse peripheral nerve disorders such as polyneuropathies. Usual nerve conduction study will be showed along with less conventional tests, either motor or sensory, in upper and lower limbs.

Number of participants Up to 50 persons Early booking is recommended.

Supported by CareFusion

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 07.30 – 09.00

TEACHING COURSES

COURSE DIRECTORS:

Claudio Baracchini, PADOVA, ITALY Carlos Molina, BARCELONA, SPAIN Zsolt Garami, BUDAPEST, HUNGARY / HOUSTON, TX, USA László Olah, DEBRECEN, HUNGARY

Number of participants Up to 50 persons Early booking is recommended.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

We recommend the participation for those medical doctors who already practised neurosonological examinations but are not familiar with the technical details, or for those who would like to start working in the field of neurosonology, and therefore would like to gain practical information. Experienced neurosonologists will demonstrate extra- and transcranial ultrasound investigations on voluntary out-patients with extra- and intracranial vascular diseases.

MONDAY, SEPTEMBER 12, 2011

TEACHING COURSE 21: HANDS-ON COURSE ON DOPPLER SONOGRAPHY PRACTICAL DEMONSTRATION IN FOUR GROUPS

51

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 CO-SPONSORSHIP 07.30 – 09.00

TEACHING COURSES

TEACHING COURSE 22: HANDS-ON COURSE ON CLINICAL NEUROPHYSIOLOGY ELECTROMYOGRAPHY (EMG) AND NERVE CONDUCTION STUDIES (NCS)

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

MONDAY, SEPTEMBER 12, 2011

52

CHAIRPERSON:

Reinhard Dengler, HANNOVER, GERMANY

EMG and NCS are well established clinical neurophysiological methods of particular importance in the diagnosis of diseases of muscle and nerve. EMG can separate myopathies from neuropathies and NCS helps to distinguish between demyelinating and axonal-degenerative disorders. Both techniques require practice and experience. This course aims at providing basic knowledge of EMG and NCS based on practical demonstration. The essential steps of an EMG study and of NCS will be demonstrated and the findings will be discussed as actually recorded. Course participants can involve and have the opportunity to increase and to foster their knowledge in these techniques.

Number of participants Up to 50 persons Early booking is recommended.

Breakfast will be provided. Supported by CareFusion

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 15.30 – 17.00

TEACHING COURSES

FREE TEACHING COURSE 23 HOW TO DO A TREATMENT TRIAL COURSE DIRECTOR:

Making trials powerful enough: the stroke example Stefano Ricci, Città di Castello, ITALY How to measure and analyse what we want to measure in trials Jeremy Hobart, Plymouth, UK

Number of participants Up to 50 persons Early booking is recommended.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

How to synthesize the evidence: the MS example Graziella Filippini, Milan, ITALY

MONDAY, SEPTEMBER 12, 2011

Richard Hughes, LONDON, UK

53

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 CO-SPONSORSHIP 07.30 – 09.00

TEACHING COURSES

TEACHING COURSE 24: HANDS-ON COURSE ON CLINICAL NEUROSONOLOGY TUESDAY, SEPTEMBER 13, 2011 15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

CHAIRPERSON:

Manfred Kaps, GIESSEN, GERMANY

Early booking is recommended.

54

This hands-on course will address hot topics of neurosonology and provide an update of guidelines for practical applications such as classification of stenoses. Life demo will illustrate extra- and transcranial colour duplex applications.

Number of participants Up to 50 persons

Supported by CareFusion

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 07.30 – 09.00

TEACHING COURSES

CHAIRPERSON:

Reinhard Dengler, HANNOVER, GERMANY

Introduction and history taking Heinz Lahrmann, Vienna, AUSTRIA Bedside investigations and sudomotor tests Walter Struhal, Linz, AUSTRIA

Case presentations and introduction to practical testing Faculty The participants of this TC will be introduced to the most basic tests of the autonomic nervous system (ANS). After a short introduction to the physiology of ANS the importance of history taking and beside investigations will be elucidated. Participants will learn about some tests of the sudomotor system (eg. sympathetic skin response test). Standard techniques to test the cardiovascular system will be presented (eg. analysis of heart rate variability). Interpretation of the results of autonomic testing will be discussed and data from patients with different autonomic disorders will be presented. A short introduction to practical work is planned. At the end of this TC the participants will have a basic knowledge of the most frequently used autonomic tests, their indications and interpretations.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Standard tests of the cardiovascular system Isabel Rocha, Lisbon, PORTUGAL

TUESDAY, SEPTEMBER 13, 2011

TEACHING COURSE 25: HANDS-ON AUTONOMIC TESTING FROM BEDSIDE TO LABORATORY INVESTIGATIONS OF ANS DISORDERS

55

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 CO-SPONSORSHIP 20.30

SCIENTIFIC GULYÁS DINNER

SCIENTIFIC GULYÁS DINNER: NEUROIMMUNOLOGY: A WALK THROUGH THE WOODS

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SUNDAY, SEPTEMBER 11, 2011

56

Hugh Willison, GLASGOW, UK

The immune system’s fascination with the brain is only matched by the brain’s fascination with the immune system. So intimately are these two vast networks integrated that it is generally impossible to decipher which tail is wagging which dog. Every corner of basic and clinical brain sciences harbours important immunological perspectives, extending well beyond the traditional neuroimmunological disorders. Our evening will consider a range of factual examples that illustrate these complexities, and take a light-hearted evolutionary and metaphysical journey into how and why these two great biological systems became such close friends.

Number of participants Up to 50 persons Early booking is recommended.

Price per person € 50,–

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 08.30 – 10.30

MAIN TOPICS

MAIN TOPIC 1: TRANSLATIONAL RESEARCH IN MOVEMENT DISORDERS

Transplantation and stem cell research in movement disorders – where are we now? Roger Barker, Cambridge, UK Timing of neuroprotection in Parkinson’s disease Werner Poewe, Innsbruck, AUSTRIA

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Translational research in ataxia Massimo Pandolfo, Brussels, BELGIUM

SUNDAY, SEPTEMBER 11, 2011

CONVENOR:

Werner Poewe, INNSBRUCK, AUSTRIA

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

57

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 CO-SPONSORSHIP 08.30 – 10.30

MAIN TOPIC 2: NEUROBIOLOGY OF MIGRAINE CONVENOR:

Messoud Ashina, COPENHAGEN, DENMARK

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SUNDAY, SEPTEMBER 11, 2011

58

Increased frequency of stroke and white matter hyperintensities in migraine Hans-Christoph Diener, Essen, GERMANY Genetics of migraine: the prospects of personalized therapy Arn van den Maagdenberg, Leiden, THE NETHERLANDS Origin of pain in migraine and future drug targets Messoud Ashina, Copenhagen, DENMARK

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

MAIN TOPICS

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 08.30 – 10.30

MAIN TOPICS

MAIN TOPIC 3: RECENT ADVANCES IN NEUROCRITICAL CARE

Mechanical ventilation in acute neurologic disorders: recent advances Béla Fulesdi, Debrecen, HUNGARY Acute management of post-cardiac arrest encephalopathy Maxwell S. Damian, Leicester, UK

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Intensive therapy of acute neuroinfections Erich Schmutzhard, Innsbruck, AUSTRIA

SUNDAY, SEPTEMBER 11, 2011

CONVENORS:

Béla Fulesdi, DEBRECEN, HUNGARY Hubert Kwiecinski, WARSAW, POLAND

59

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 CO-SPONSORSHIP 08.30 – 10.30

MAIN TOPICS

MAIN TOPIC 4: BIOTHERAPIES FOR NEUROLOGICAL DISEASES: MECHANISMS OF ACTION, EFFICACY AND SAFETY CONVENOR:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SUNDAY, SEPTEMBER 11, 2011

60

David Adams, PARIS, FRANCE

General overview on biotherapies Hugh Willison, Glasgow, UK Antisens oligonucleotids for neurological diseases Gert-Jan van Ommen, Leiden, THE NETHERLANDS Humanized monoclonal antibodies for neurological diseases Marinos Dalakas, London, UK Biotherapy for familial amyloid polyneuropathies David Adams, Paris, FRANCE

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 08.30 – 10.30

MAIN TOPICS

MAIN TOPIC 5: INVASIVE TREATMENT STRATEGIES FOR ISCHEMIC STROKE

Limitations of conservative treatment and new attempts to reperfuse and limit tissue damage Wolf-Dieter Heiss, Cologne, GERMANY Intraarterial treatment strategies Heinrich Mattle, Bern, SWITZERLAND

Intravascular cell therapy in stroke: challenges and promises Jukka Jolkkonen, Kuopio, FINLAND

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Percutaneous transluminal angioplasty and stenting: an alternative to carotid endarterectomy? Martin Brown, London, UK

MONDAY, SEPTEMBER 12, 2011

CONVENOR:

Wolf-Dieter Heiss, COLOGNE, GERMANY

61

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 CO-SPONSORSHIP 08.30 – 10.30

MAIN TOPIC 6: FRONTOTEMPORAL DEMENTIA (FTD) – FROM MOLECULE TO BEHAVIOUR CONVENOR:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

MONDAY, SEPTEMBER 12, 2011

62

Albert Ludolph, ULM, GERMANY

The spectrum of FTDs Albert Ludolph, Ulm, GERMANY The genetics of FTD Peter Heutink, Amsterdam, THE NETHERLANDS Targets for intervention from neuropathology Tamas Revesz, London, UK

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

MAIN TOPICS

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 08.30 – 10.30

MAIN TOPICS

MAIN TOPIC 7: ACUTE VERTIGO: NEUROPHYSIOLOGY, CLINICAL APPROACH, AND TREATMENT

Neurophysiology of acute vertigo Dominik Straumann, Zurich, SWITZERLAND Clinical approach to acute vertigo Barry M Seemungal, London, UK

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Medical treatment of peripheral vestibular disorders Michael Strupp, Munich, GERMANY

MONDAY, SEPTEMBER 12, 2011

CONVENOR:

Dominik Straumann, ZURICH, SWITZERLAND

63

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 CO-SPONSORSHIP 08.30 – 10.30

MAIN TOPIC 8: PARADIGMS IN EPILEPSY TREATMENT CONVENOR:

Alla Guekht, MOSCOW, RUSSIA

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

MONDAY, SEPTEMBER 12, 2011

64

Pregnancy and epilepsy: outcome for the child Gyri Veiby, Bergen, NORWAY Seizures and epilepsy after stroke Alla Guekht, Moscow, RUSSIA Identifying and preventing sudden unexpected death in epilepsy Torbjörn Tomson, Stockholm, SWEDEN

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

MAIN TOPICS

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 08.30 – 10.30

MAIN TOPICS

MAIN TOPIC 9: ATRIAL FIBRILLATION AND STROKE: NEW INSIGHTS, NEW DILEMMAS

Incidence, risk factors and specificities of stroke in patients with atrial fibrillation Michael Hennerici, Mannheim, GERMANY Current state of anthithrombotic therapies for stroke prevention in atrial fibrillation Jean-Louis Mas, Paris, FRANCE

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Current status of other therapeutic opportunities TBA

TUESDAY, SEPTEMBER 13, 2011

CONVENOR:

Michael Hennerici, MANNHEIM, GERMANY

65

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 CO-SPONSORSHIP 08.30 – 10.30

MAIN TOPICS

MAIN TOPIC 10: A TRANSLATIONAL VIEW ON NARCOLEPSY: WHAT WE KNOW, AND WHAT WE DON’T KNOW TUESDAY, SEPTEMBER 13, 2011 15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

CONVENOR:

Christian Baumann, ZURICH, SWITZERLAND

Putting it together: the pathophysiology and treatment of narcolepsy Christian Baumann, Zurich, SWITZERLAND

66

The basics: mechanism of sleep-wake regulation in healthy and disordered sleep Christelle Peyron, Lyon, FRANCE The clinics: symptoms and diagnosis of narcolepsy Sebastiaan Overeem, Nijmegen, THE NETHERLANDS

Remaining mysteries: etiology, genetics, and metabolism Tom Scammell, Boston, MA, USA

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 08.30 – 10.30

MAIN TOPICS

MAIN TOPIC 11: NEUROPROTECTION AND ENVIRONMENTAL FACTORS IN MULTIPLE SCLEROSIS

Axonal protection and repair in demyelinating diseases Martin Kerschensteiner, Munich, GERMANY The role of astrocytes and CNS stem cells in maintaining the integrity of neuronal circuits Andras Lakatos, Cambridge, UK

Vitamin D, lifestyle factors and risk for multiple sclerosis Kjell-Morten Myhr, Bergen, NORWAY

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Infections and risk for multiple sclerosis Alberto Ascherio, Boston, MA, USA

TUESDAY, SEPTEMBER 13, 2011

CONVENORS:

Kjell-Morten Myhr, BERGEN, NORWAY Andras Lakatos, CAMBRIDGE, UK

67

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 08.30 – 10.30

MAIN TOPIC 12: CONTROVERSIES IN NEUROLOGY CONVENORS:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

TUESDAY, SEPTEMBER 13, 2011

68

Detlef Kömpf, LÜBECK, GERMANY Nils Erik Gilhus, BERGEN, NORWAY

Can therapy modify natural evolution of Parkinson’s disease? PRO: Olivier Rascol, Toulouse, FRANCE CONTRA: Andrew J Lees, London, UK Long-term efficacy of immunomodulators in MS PRO: Maria Trojano, Bari, ITALY CONTRA: Jackie Palace, Oxford, UK Are extensive examinations necessary in the diagnosis of Alzheimer’s disease? PRO: Bruno Dubois, Paris, FRANCE CONTRA: Roy Jones, Bath, UK Patent foramen ovale in patients with ischemic stroke of unknown cause: to close? PRO: Patrik Michel, Lausanne, SWITZERLAND CONTRA: Jean-Louis Mas, Paris, FRANCE

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

MAIN TOPICS

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 12.00 – 13.00

EFNS LECTURE ON CLINICAL NEUROLOGY

EFNS LECTURE ON CLINICAL NEUROLOGY

The widening spectrum of antibody-mediated neurological diseases: from neuromuscular junction to brain Angela Vincent, Oxford, UK

Angela C Vincent MB BS, MSc, FRCP (Hon), FRCPath, FMedSci, PhD (Hon Bergen) Angela Vincent (Hon PhD Bergen) FRCPath FRCP FMedSci is Emeritus Professor of Neuroimmunology at the University of Oxford, and an Emeritus Fellow of Somerville College. She holds an Honorary Consultant position in Immunology and runs the Clinical Neuroimmunology service which is an international referral centre for the measurement of antibodies in neurological diseases. She is also a part-time Honorary Consultant and Professor at the Institute of Neurology, UCL, and an Associate Editor of Brain. She was formerly Head of Department of Clinical Neurology (2005-2008), served on the MRC Neurosciences and Mental Health Board (2004-2008), and was President of the International Society of Neuroimmunology (2001-2004). She has spent over 35 years working on autoantibodies to specific receptors, ion channels and related proteins in neurological diseases, and published more than 300 peer-reviewed scientific papers, many of them in the leading journals. BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

There are an increasing number of relatively rare conditions that are associated with the presence of specific serum autoantibodies. In the peripheral nervous system, diseases such as myasthenia gravis and the Lambert Eaton myasthenic syndrome are directly caused by autoantibodies to muscle or neuronal ion channels and receptors, including muscle specific kinase. The diseases improve substantially with immunotherapies. In the central nervous system, autoantibodies to a variety of intracellular neuronal targets are well-recognised in tumour-associated (paraneoplastic) neurological diseases that result when the immune system reacts with tumour antigens which are shared by the nervous system, but these patients do not generally improve with treatments and have a poor prognosis. More recently, however, it has become clear that autoantibodies to specific receptors and ion channels or associated proteins can lead to neurological diseases involving many regions of the central nervous system. These antibodies can be detected in the serum and usually in the cerebrospinal fluid and are thought to be directly pathogenic. Although often severely affected, most patients derive considerable benefits from immunotherapies. In addition, antibodies to the water channel aquaporin-4 are highly specific for neuromyelitis optica and related syndromes. All of these recent discoveries have greatly enhanced the recognition and, hence, treatment of these acquired neurological disorders.

TUESDAY, SEPTEMBER 13, 2011

CHAIRPERSONS:

Richard Hughes, LONDON, UK Nils Erik Gilhus, BERGEN, NORWAY

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95% of your adult patients have had chickenpox. 1 out of 4 will suffer from zoster.

CO-SPONSORSHIP

Vaccination is now possible.

Abridged Prescribing Information for use in European Area Zostavax® powder and solvent for suspension for injection Shingles (herpes zoster) vaccine (live) Refer to Summary of Product Characteristics for full product information. Presentation: Zostavax is supplied as a vial of powder and a pre-filled syringe of solvent. After reconstitution, 1 dose (0.65 ml) contains not less than 19400 PFU1 of Varicella-zoster virus2, Oka/Merck strain, (live, attenuated) 1PFU = Plaque-forming units 2produced in human diploid (MRC-5) cells Indications: Zostavax is indicated for prevention of herpes zoster (“zoster” or shingles) and herpes zoster-related post-herpetic neuralgia (PHN). ZOSTAVAX is indicated for immunization of individuals 50 years of age or older. Posology and method of administration: Individuals should receive a single dose administered subcutaneously. The need for a second dose is currently unknown. The vaccine is to be injected subcutaneously, preferably in the deltoid region. Contraindications: Hypersensitivity to the active substance, to any of the excipients or trace residuals (e.g., neomycin). Primary and acquired immunodeficiency states due to conditions such as: acute and chronic leukaemias; lymphoma; other conditions affecting the bone marrow or lymphatic system; immunosuppression due to HIV/AIDS; cellular immune deficiencies. Immunosuppressive therapy (including high-dose corticosteroids); however, Zostavax is not contraindicated for use in individuals who are receiving topical/inhaled corticosteroids or low-dose systemic corticosteroids or in patients who are receiving corticosteroids as replacement therapy, e.g., for adrenal insufficiency. Active untreated tuberculosis. Pregnancy. Warnings and precautions: Appropriate medical treatment and supervision should always be readily available in case of a rare anaphylactic/anaphylactoid reaction following the administration of the vaccine, as there is a possibility of hypersensitivity reactions, not only to the active substances, but also to the excipients and trace residuals (e.g., neomycin) present in the vaccine. Zostavax is not indicated for treatment of zoster or PHN. Deferral of vaccination should be considered in the presence of fever. Vaccination with Zostavax may not result in protection in all vaccine recipients. The safety and efficacy of Zostavax have not been established in adults who are known to be infected with HIV with or without evidence of immunosuppression. Transmission: In clinical trials with Zostavax, transmission of the vaccine virus has not been reported. However; post-marketing experience with varicella vaccines suggests that transmission of vaccine virus may occur rarely between vaccinees who develop a varicellalike rash and susceptible contacts (for example, VZV-susceptible infant grandchildren). Transmission of vaccine virus from varicella vaccine recipients without a varicella-zoster virus (VZV)-like rash has been reported but has not been confirmed. This is a theoretical risk for vaccination with Zostavax. The risk of transmitting the attenuated vaccine virus to a susceptible individual should be weighed against the risk of developing natural herpes zoster that could be transmitted to a susceptible individual. Interaction: ZOSTAVAX can be administered concomitantly with inactivated influenza vaccine as separate injections and at different body sites. Zostavax and 23-valent pneumococcal polysaccharide vaccine should not be given concomitantly. No data are currently available regarding concomitant use with other vaccines. Concurrent administration of Zostavax and anti-viral medications known to be effective against VZV has not been evaluated. Pregnancy and lactation: Zostavax is not intended to be administered to pregnant nor breastfeeding women. Undesirable effects: Very common: erythema, pain/tenderness, swelling. Common: headache, haematoma, pruritus, warmth. For a complete list of undesirable effects including those reported during post-marketing surveillance, please refer to the Summary of Product Characteristics. Marketing Authorisation holder: Sanofi Pasteur MSD SNC, 8 rue Jonas Salk, F-69007, Lyon, France Date of creation: February 2010 MA numbers: EU/1/06/341/ 003-013 Date of MA approval: 19 May 2006

Sanofi Pasteur MSD S.N.C. au capital de 60 000 000 EUR - R.C.S. LYON B 392 032 934 - CO00582 - October 2010

The 1 st zoster vaccine, for patients over 50.

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 15.30 – 17.00

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 1: OPTIMISING STROKE CARE IN EASTERN EUROPEAN COUNTRIES

Managing risk factors Kjell Asplund, Umeå, SWEDEN Value of implementing guidelines and registries Michael Brainin, Krems, AUSTRIA

In Central and Eastern European (CEE) countries, the stroke risk profile is different and the morbidity and mortality rates of stroke are much higher than in Western Europe, indicating the need for urgent measures to further decrease the burden of stroke in this region. Because of the common socio-economic and political roots, the CEE countries have similar infrastructural and human resource problems in their stroke care. The workshop will summarize the differences between the eastern and western countries (risk profiles, morbidity, mortality, stroke care and stroke programmes) and will try to formulate how to optimize the stroke care in CEE countries.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

How to organize an efficient stroke care in Eastern European countries? László Csiba, Debrecen, HUNGARY

SUNDAY, SEPTEMBER 11, 2011

CONVENOR:

László Csiba, DEBRECEN, HUNGARY

71

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 CO-SPONSORSHIP 15.30 – 17.00

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 2: NEW PERSPECTIVES IN NEUROLOGICAL THERAPIES CONVENOR:

Maria Judit Molnar, BUDAPEST, HUNGARY

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SUNDAY, SEPTEMBER 11, 2011

72

“One-fits-to all” or tailored medicine: How far are we from personalized medicine in neurology? Stephan Züchner, Miami, FL, USA The effect of biotechnology on neurological therapies Michael Sinnreich, Basel, SWITZERLAND Gene therapy in neurology – still a dream or reality? Maria Judit Molnar, Budapest, HUNGARY

Biotechnology plays an increasing role in the development of new therapeutic modalities. Monoclonal antibodies, enzyme replacement therapies are already present in the everyday clinical practice. Cell and gene therapy is a real hope, clinical trials are ongoing presently in Duchenne muscular dystrophy and in Parkinson’s disease. Recent rapid advances in genomics and molecular biology are beginning to reveal a large number of possible new, genome-related, molecular markers for the presence of disease, susceptibility to disease, or differential response to treatment. Such markers can serve as the basis of new genomics-based diagnostic tests for identifying and/ or confirming disease, assessing an individual’s risk of disease, identifying patients who will benefit from particular interventions, or tailoring dosing regimens to individual variations in metabolic response. These new diagnostics can also pave the way for development of new therapeutics specifically targeted at the physiological consequences of the genetic defect(s) associated with a patient’s disease.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 15.30 – 17.00

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 3: THE EARLY COURSE OF MULTIPLE SCLEROSIS CONVENOR:

Biomarkers for defining prognosis and guiding therapy Florian Deisenhammer, Innsbruck, AUSTRIA Neuropsychological impairment: impact on the early disease's course and treatment decisions Pablo Villoslada, Barcelona, SPAIN

The workshop aims to discuss hands-on concepts for the contemporary management of the very early course of multiple sclerosis on the basis of individual cases and with regard to the most recent immunobiological understanding. Following an introduction to the field, each speaker will introduce representative cases, and diagnostic and therapeutic suggestions will be put up for discussion. The convenor will actively involve the attendants in decision-making processes and lead an interactive discussion.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

The radiologically isolated syndrome: a delicate situation requiring pragmatic concepts Johann Sellner, Munich, GERMANY

SUNDAY, SEPTEMBER 11, 2011

Johann Sellner, MUNICH, GERMANY

73

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 CO-SPONSORSHIP 15.30 – 17.00

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 4: NEW INSIGHTS INTO TREATING MITOCHONDRIAL DISEASE CONVENOR:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SUNDAY, SEPTEMBER 11, 2011

74

Laurence Bindoff, BERGEN, NORWAY

Treating adult patients with mitochondrial disease: best clinical practice Douglas M. Turnbull, Newcastle, UK Children with mitochondrial disease: new diseases provide new therapeutic possibilities Massimo Zeviani, Milan, ITALY Models of mitochondrial disease and how these are being used to identify novel treatments Laurence Bindoff, Bergen, NORWAY

This workshop will focus on management of patients with mitochondrial disease, what is currently the accepted “best clinical practice” and which new therapies are available or becoming available. All the speakers are clinical scientists with extensive clinical and laboratory experience of mitochondrial disease.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 15.30 – 17.00

FOCUSED WORKSHOPS

CONVENOR:

Pierre-Marie Preux, LIMOGES, FRANCE

Epidemiology of epilepsy in resource-poor countries: an emerging public health issue Pierre-Marie Preux, Limoges, FRANCE Methodological challenges in epilepsy research and control in tropical epilepsy Peter Odermatt, Basel, SWITZERLAND

Epilepsy is two to three times more frequent in tropical areas compared to the developed world, most of which is caused by infectious diseases. The pathogenesis of epilepsy following these infections may elucidate the cause of epilepsy in Europe. Our goal is to bring to the attention of the European neurologists the specificities of epilepsy in tropical countries. Comparative epidemiology will be presented raising hypotheses to explain the differences. Specific aetiologies such as infectious diseases will be reviewed. A specific presentation will focus on cerebral malaria as a cause of epilepsy.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Falciparum malaria and epilepsy Charles Newton, London, UK

SUNDAY, SEPTEMBER 11, 2011

FOCUSED WORKSHOP 5: EPILEPSY IN RESOURCE-POOR COUNTRIES: AN EMERGING ISSUE FOR EUROPEAN PUBLIC HEALTH

75

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 CO-SPONSORSHIP 15.30 – 17.00

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 6 MOVEMENT DISORDERS OF THE FACE CONVENOR:

Giovanni Fabbrini, ROME, ITALY

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

MONDAY, SEPTEMBER 12, 2011

76

Facial dyskinesias: clinical aspects and differential diagnosis Giovanni Fabbrini, Rome, ITALY Pathophysiology of facial dyskinesias Josep Valls-Solé, Barcelona, SPAIN Medical treatment of facial dyskinesias Kailash Bhatia, London, UK

The aims of this focused workshop are: To identify and classify facial dyskinesias To discuss the pathophysiological mechanisms underlying the different types of facial dyskinesias 3. To evaluate the options for the treatment of facial dyskinesias 1. 2.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 15.30 – 17.00

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 7: NEUROMODULATION IN HEADACHE CONVENOR:

Stimulation of the major occipital nerves (NOS) for the treatment of chronic refractory headache Zaza Katsarava, Essen, GERMANY Spinal cord stimulation for the treatment of chronic headache Holger Kaube, Freiburg, GERMANY

The workshop will address new non-pharmacological methods to treat patients with chronic headache who do not or no longer respond to medication. NOS and spinal cord stimulation are discussed in the context of chronic cluster headache and chronic migraine. DC cortical stimulation is a new way of preventing migraine.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

DC cortical stimulation in headache prophylaxis Walter Paulus, Göttingen, GERMANY

MONDAY, SEPTEMBER 12, 2011

Holger Kaube, FREIBURG, GERMANY

77

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 CO-SPONSORSHIP 15.30 – 17.00

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 8: WHITE MATTER CHANGES (LEUKOARAIOSIS) CONVENOR:

Natan Bornstein, TEL-AVIV, ISRAEL

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

MONDAY, SEPTEMBER 12, 2011

78

Leukoaraiosis – the magnitude of the problem Natan Bornstein, Tel-Aviv, ISRAEL Pathological features of WMC Tibor Hortobagyi, London, UK Clinical consequences; dementia and gait disturbances Reinhold Schmidt, Graz, AUSTRIA

White matter changes (WMC) are common features on neuroimaging and are associated with various risk-factors. However, the pathological features of these phenomena are not well described and studied. The clinical consequences of WMC are significant and contribute to the overall disability in the elderly. This workshop will highlight the magnitude of the phenomenon, will discuss the pathological processes involved and the clinical features of this important and common neuroimaging feature.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 15.30 – 17.00

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 9: COMMON DILEMMAS IN MUSCLE DISEASE CONVENOR:

A diagnostic approach and management of pain/cramp syndromes David Hilton-Jones, Oxford, UK A diagnostic approach to pauci- or asymptomatic hyperCKemia Theodoros Kyriakides, Nicosia, CYPRUS

The general neurologist is often confronted with patients presenting with muscle pain/cramps, asymptomatic hyperCKemia and less frequently rhabdomyolysis. He/she has the dilemma of how and to what extent to investigate these patients. At the end of the workshop the attendants should be able to have a rational plan of action on managing these patients.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

A diagnostic approach to the causes of rhabdomyolysis John Vissing, Copenhagen, DENMARK

MONDAY, SEPTEMBER 12, 2011

Theodoros Kyriakides, NICOSIA, CYPRUS

79

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 CO-SPONSORSHIP 15.30 – 17.00

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 10: NEUROFIBROMATOSES AND THE NEUROLOGIST CONVENOR:

Rosalie E. Ferner, LONDON, UK

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

MONDAY, SEPTEMBER 12, 2011

80

Neurofibromatosis 1 Rosalie E. Ferner, London, UK Neurofibromatosis 2 and schwannomatosis Michel Kalamarides, Paris, FRANCE Genetics of the neurofibromatosis Eric Legius, Leuven, BELGIUM Novel therapies for the neurofibromatoses David Gutmann, St. Louis, MO, USA

Neurofibromatosis 1 and 2 are inherited conditions that have a major impact on the nervous system and predispose to tumour formation. The neurologist has a pivotal position in the multi-disciplinary management of individuals with the neurofibromatoses. The current diagnostic criteria and differential diagnosis of neurofibromatosis 1 and 2 and the delineation of clinical phenotype will be presented. Progress in surgical management and auditory rehabilitation of individuals with NF2 will be discussed. The workshop will highlight advances in molecular biology and mouse models that have improved our understanding of disease pathogenesis and permitted the development of targeted therapy for the neurofibromatoses.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 15.00 – 16.30

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 11: UPDATE ON MULTIPLE SYSTEM ATROPHY

Disease progression – clinical markers and imaging Carlo Colosimo, Rome, ITALY Pathogenesis Gregor Wenning, Innsbruck, AUSTRIA

The aims of this workshop are to: q*EFOUJGZQSFEJDUPSTBOENBSLFSTPGQSPHSFTTJPO q$SJUJDBMMZBTTFTTUIFQPUFOUJBMPGJNBHJOHQSPHSFTTJPONBSLFSTDPWFSJOHBEWBODFE.3* techniques and functional SPECT of PET markers q6OEFSTUBOEUIFDPOUSJCVUJPOPGHFOFUJDBOEFOWJSPONFOUBMGBDUPSTJOUIF pathogenesis q%FUFSNJOFUIFBCOPSNBMDFMMVMBSDBTDBEFTTPGBSJEFOUJǸFE q-FBSOBCPVUUIFQSFWJPVTBOEPOHPJOHUIFSBQFVUJDJOUFSWFOUJPOUSJBMTJO.4"

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Experimental therapeutics Olivier Rascol, Toulouse, FRANCE

TUESDAY, SEPTEMBER 13, 2011

CONVENORS:

Gregor Wenning, INNSBRUCK, AUSTRIA Carlo Colosimo, ROME, ITALY

81

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 CO-SPONSORSHIP 15.00 – 16.30

FOCUSED WORKSHOP 12: CEREBRAL MICROBLEEDS CONVENOR:

Charlotte Cordonnier, LILLE, FRANCE

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

TUESDAY, SEPTEMBER 13, 2011

82

How to detect microbleeds? Mark van Buchem, Leiden, THE NETHERLANDS Microbleeds and antithrombotic treatments David Werring, London, UK Microbleeds in Alzheimer’s disease Charlotte Cordonnier, Lille, FRANCE

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

FOCUSED WORKSHOPS

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 15.00 – 16.30

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 13: OPPORTUNISTIC INFECTIONS OF THE NERVOUS SYSTEM

Herpes viruses (VZV, CMV, EBV, HSV) Uta Meyding-Lamade, Frankfurt, GERMANY Following immunosuppressive therapy for neurological conditions Israel Steiner, Petach Tiqva, ISRAEL

Opportunistic infections of the nervous system in immune-compromised patients pose an important diagnostic and therapeutic challenge. Understanding the neurological context and awareness of the neurological symptomatology are essential for correct diagnosis and immediate therapy in order to ensure the best prognosis. This workshop will focus on several aspects of this situation: infections due to human herpes viruses and infections in the context of immune suppression under bone marrow and organ transplantation. Currently, opportunistic infections due to therapies directed against neurological conditions attract much attention. This will also be presented and discussed.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

After bone marrow and organ transplantation Peter Kennedy, Glasgow, UK

TUESDAY, SEPTEMBER 13, 2011

CONVENOR:

Israel Steiner, PETACH TIQVA, ISRAEL

83

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 CO-SPONSORSHIP 15.00 – 16.30

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 14: MONOCLONAL GAMMOPATHIES OF UNDETERMINED SIGNIFICANCE (MGUS) AND PERIPHERAL NERVE DISORDERS

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

TUESDAY, SEPTEMBER 13, 2011

84

CONVENOR:

John Wokke, UTRECHT, THE NETHERLANDS

What the neurologist should know about plasma cell dyscrasias and primary amyloidosis Giampaolo Merlini, Pavia, ITALY Splitting of lumping of clinical syndromes John Wokke, Utrecht, THE NETHERLANDS Treatment strategies Rob Hadden, London, UK

Monoclonal proteins can be a coincidental finding in the elderly. Alternatively, a monoclonal spike may be harbinger or marker of a serious disease. In the past decade, several new syndromes and diseases have been identified. The clinical spectrum of each of these can show large variation. On the one hand, a monoclonal IgG protein can represent a risk factor for CIDP without treatment consequences. On the other hand, IgM-MGUSP with or without anti-myelin associated glycoprotein antibodies can be a severely incapacitating ataxic neuropathy urging experimental treatments. Cross-reactivity with gangliosides epitopes may explain antineural immunoreactivity of M-proteins. In this focused workshop we aim to teach the haematological aspects, review the state-of-the-art of identifying neurological syndromes, and explore when and how to install treatment.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 15.00 – 16.30

FOCUSED WORKSHOPS

FOCUSED WORKSHOP 15: THE CHRONIC SECONDARY HEADACHE CONVENOR:

Classification and diagnosis of the chronic secondary headache Jes Olesen, Copenhagen, DENMARK Primary intracranial hypotension and hypertension Stefan Evers, Münster, GERMANY

The participants will learn about the new say in which the secondary headaches are going to be defined by their diagnostic criteria. Furthermore, the most important chronic secondary headaches will be described and the diagnosis of these headaches discussed. Primary intracranial hypotension and hypertension are common and important headache entities. Their mechanisms, diagnosis and treatment will be covered in detail. Chronic headache after intracranial disorder is a relatively new concept. Normally, headache after e.g. brain tumor operation or stroke is short lasting. However, it is now realized that it may become chronic in a substantial number of patients. The diagnosis and treatment of such cases will be discussed.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Chronic headache after intracranial disorder Andreas Straube, Munich, GERMANY

TUESDAY, SEPTEMBER 13, 2011

Jes Olesen, COPENHAGEN, DENMARK

85

PRELIMINARY PROGRAMME

SATURDAY, SEPTEMBER 10, 2011 CO-SPONSORSHIP 16.30 – 17.30

SPECIAL SESSIONS

BRAIN DISORDERS IN EUROPE: FUTURE DIRECTIONS

SYMPOSIUM DEDICATED TO THE 70TH BIRTH ANNIVERSARY OF PROFESSOR JES OLESEN IN RECOGNITION OF HIS OUTSTANDING CONTRIBUTION TO THE FIELDS OF NEUROLOGY AND DEVELOPMENT OF THE EFNS AND THE EUROPEAN BRAIN COUNCIL

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SATURDAY, SEPTEMBER 10, 2011

86

CHAIRPERSONS:

Messoud Ashina, COPENHAGEN, DENMARK Rigmor Jensen, COPENHAGEN, DENMARK

The EFNS and the European Brain Council: history and future perspectives Richard Hughes, London, UK Recent progress and future direction of neurodegenerative disease research Gunhild Waldemar, Copenhagen, DENMARK 30 years of headache research in Europe Michel Ferrari, Leiden, THE NETHERLANDS

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 14.30 – 17.00

SPECIAL SESSIONS

EUROPEAN BASAL GANGLIA CLUB SESSION CONVENOR:

The C. David Marsden Invited Lecture 2011 The nosology of Parkinson’s disease Andrew Lees, London, UK Video session

SUNDAY, SEPTEMBER 11, 2011

Werner Poewe, INNSBRUCK, AUSTRIA

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

87

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 CO-SPONSORSHIP 15.00 – 17.00

SPECIAL SESSIONS

EFNS-EFNA SPECIAL SESSION „THE GOOD LIFE“ HOST:

Mary G. Baker, PRESIDENT EFNA

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

SUNDAY, SEPTEMBER 11, 2011

88

The diagnosis of a severe neurological disease is a watershed in people’s lives. Life changes forever, but that change needs not be completely negative and many recover skills and find strengths they were unaware of before. In spite of this major earthquake in their lives ‘Life Can Be Good’ and the process of rehabilitation for the patient is often one of re-education, hope and discovery or re-discovery of personal capability and quality of life. A session organised for neurologists by the European Federation of Neurological Associations (EFNA), where patients and carers living with debilitating illnesses show how they are still able to enjoy their pre-illness skills and expertise, and share them with others. A positive approach to the practicalities of life and disease can often bring unexpected bonuses and this session uses musical and other performance, with a presentation by a well-known international scientist, to give the audience an enjoyable and interesting view of post-clinic life for patients. In Budapest 2011, we will bring together the music of Franz Liszt and the Hungarian dances of Johannes Brahms, to focus on the effects of this area of human expression in neurology.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

SUNDAY, SEPTEMBER 11, 2011 17.30 – 18.40

SPECIAL SESSIONS

EAYNT SESSION

EAYNT present and future Martin Rakusa, President, EAYNT Edina Varga, President-elect, EAYNT

17:40-18:00

How to select the department to work at and become a combined neuroscientist/neurologist? Wolfgang Oertel, Marburg, GERMANY

18:00-18:20

The borderlands between neurology, psychiatry and internal medicine: future challenges and opportunities Gunhild Waldemar, Copenhagen, DENMARK

18:20-18:40

Neurology: reading, learning and real life Ray Chaudhuri, London, UK

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

17:30-17:40

SUNDAY, SEPTEMBER 11, 2011

HOST:

Edina Varga, DIANALUND, DENMARK Martin Rakusa, MARIBOR, SLOVENIA

89

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 CO-SPONSORSHIP 15.00 – 17.00

EFNS–ILAE-CEA JOINT SESSION TREATMENT OF EPILEPSIES CHAIRPERSONS:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

MONDAY, SEPTEMBER 12, 2011

90

Hermann Stefan, ERLANGEN, GERMANY Antonio Gil-Nagel, MADRID, SPAIN

Easy and difficult to treat epilepsies Ley Sander, Buckinghamshire, UK Epilepsies in women and men Gerhard Luef, Innsbruck, AUSTRIA Mono vs polytherapy Emilio Perucca, Pavia, ITALY When and when not to withdraw drugs Alla Guekht, Moscow, RUSSIA

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

SPECIAL SESSIONS

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 15.00 – 17.00

SPECIAL SESSIONS

SPECIAL SESSION JOINT SESSION EFNS – MEDITERRANEAN NEUROLOGICAL SOCIETIES: MOVEMENT DISORDERS PRESIDENT PAUNS: Ahmad PRESIDENT EFNS: Richard

Khalifa, DAMASCUS, SYRIA Hughes, LONDON, UK

Special news: Jean-Michel Vallat, Limoges, FRANCE Management of behavioural abnormalities in PD Murat Emre, Istanbul, TURKEY

Psychogenic movement disorders Hicham Chafiq, Marrakesh, MOROCCO Surgery in Parkinson’s disease: an update Paul Bejjani, Beirut, LEBANON

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

Therapeutic approaches in dystonia Stéphane Thobois, Lyon, FRANCE

MONDAY, SEPTEMBER 12, 2011

CHAIRPERSONS:

91

PRELIMINARY PROGRAMME

MONDAY, SEPTEMBER 12, 2011 CO-SPONSORSHIP 15.00 – 17.00

SPECIAL SESSIONS

EFNS – EFNA AWARENESS SESSION CHAIRPERSONS:

Mary Baker, LONDON, UK – EFNA PRESIDENT László Vécsei, SZEGED, HUNGARY

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

MONDAY, SEPTEMBER 12, 2011

92

EFNA’s Awareness Session in Budapest will focus on three areas which will interest neurologists and other health professionals: The results of a 3-year EFNA study on quality of life of carers in Parkinson’s disease, carried out by the University of Oxford, presented by Professor Crispin Jenkinson. An analysis of the effects of neurological illness on sexual health. Practical aspects of management of Parkinson’s disease. How EUReMS (European Register for MS) will benefit patients and professionals. EUReMS will address the current lack of information and enable comparisons across the countries of the EU by merging data from existing MS national registers and collecting reliable and validated statistics from other sources.

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 10.30 – 12.00

SPECIAL SESSIONS

MUSIC AND NEUROLOGY CHAIRPERSON:

Neurological disorders in musicians Eckart Altenmüller, Hannover, GERMANY Musicogenic epilepsy and hallucinations Stefan Evers, Münster, GERMANY

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

The concept of amusias Timothy Griffiths, Newcastle, UK

TUESDAY, SEPTEMBER 13, 2011

Stefan Evers, MÜNSTER, GERMANY

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

93

PRELIMINARY PROGRAMME

TUESDAY, SEPTEMBER 13, 2011 14.30 – 16.30

SPECIAL SESSIONS

NEUROLOGY IN CENTRAL AND EASTERN EUROPE: ROOTS AND DEVELOPMENT CHAIRPERSONS:

15TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES

TUESDAY, SEPTEMBER 13, 2011

94

Sámuel Komoly, PÉCS, HUNGARY László Vécsei, SZEGED, HUNGARY

From Dezsö Miskolczy till today: the role of signalling molecules in migraine and other headaches Jes Olesen, Copenhagen, DENMARK Why have we failed our fight against Alzheimer's disease? Amos Korczyn, Tel-Aviv, ISRAEL Neurology in Russia: Bekhterev Alla Guekht, Moscow, RUSSIA Schaffer’s neurology school Daniel Bereczki, Budapest, HUNGARY Neurology in Hungary: Kálmán Sántha László Csiba, Debrecen, HUNGARY László Meduna and epilepsy today József Janszky, Pécs, HUNGARY From Környey’s neuropathology to neurochemistry today Peter Klivényi, Szeged, Hungary Pandy and CSF: historical aspects of neuroimmunology Zsolt Illés, Pécs, Hungary The view of neurogenic regulation of cerebral blood flow: yesterday and today (Endre Grastyán and László Molnár) László Oláh, Debrecen, HUNGARY

BUDAPEST, HUNGARY, SEPTEMBER 10 – 13, 2011

EFNS STOCKHOLM 2012 16TH CONGRESS OF THE EUROPEAN FEDERATION OF NEUROLOGICAL SOCIETIES STOCKHOLM, SWEDEN, SEPTEMBER 8 – 11, 2012

Don’t miss the opportunity to meet more than 5,000

EMAIL

Co-sponsored by the European Section of the Movement Disorder Society (MDS-ES)

neurologists and join us at the EFNS Congress in 2012. Co-sponsored by the European Federation of Autonomic Societies (EFAS)

Co-sponsored by the World Federation of Neurology (WFN)

CONGRESS ORGANISERS

Organised in co-operation with the Swedish Neurology Society

CO SPONSORSHIP

HOST

For details please visit www.efns.org/efns2012

EFNS 2012 [email protected] WEB www.efns.org/efns2012