MESOTHERAPY in DERMATOLOGY
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Indications z Hair:
Telogen effluvium Androgenetic Alopecia z Face : Facial rejuvenation (wrinkles + Firming) Facial pigmentation e.g. melasma.
Indications z Body
Localised fat areas . Cellulite. Stretch marks.
How To Start 1. 2. 3. 4. 5.
Materials & protocols / indication. Injection sites. Injection Depths. Needle size. Machine.
Materials Classified into : z Principals(Major) z Complementary(Minor) TIP: Mixture should contain 2-3 principals to achieve satisfactory results(>90%).
Hair z
Principals Telogen Effluvium Biotin Hair (Vitamin H/B7) Growth Pantothenic Stimulants acid (Vitamin B5)
Complementary Pyridoxine (Vitamin B6) Zinc + Azelaic acid MV + MTE
Hair z
AGA Principals Hair Growth Minoxidil Stimulants Finasteride 5-ARI
Dutasteride
Complementary Zinc + Azelaic acid
MesoHair Protocols Telogen Effluvium
Androgenetic Alopecia
Biotin (P) Dexenol(P) MV + MTE (C)
Minoxidil(P) / Dutasteride(P) + Biotin(P) Dexenol(P) Zinc + Azelaic (C)
MesoHair Injection sites & depths 1-2mm
Face MesoLift / MesoGlow z Rejuvenation
(Major)
Proven to Stimulate collagen synthesis
Hyaluronic acid z Amino acids z Vitamin C z Organic Silicium z Fibronectin + Vegetal proteins (Collagen & Elastin) z Vitamin A z
Face MesoLift / MesoGlow z Rejuvenation
Glycolic acid z Taurine z XADN z MV & MTE z
(Complementary)
Major Firming z
DMAE : 1. Potent firming acts quickly and lasts long. 2. Acts in the neuromuscular union, as a precursor of acetylcholine, the neurotransmitter responsible for muscular contraction, increasing the overall tone of the skin. z DMAE + Organic Silicium
MesoGlow Protocols Glow HA (P)
Lift (Firming) HA (P)
Silorg (P)
Silorgamine = Silorg + DMAE (P)
Purascorbol / Vitamin C (P)
Puretinol / Vitamin A (P)
Xadenal (C)
Taurinox (C)
MesoGlow/Lift Injection sites & depths 1-2mm
Face Pigmentation Principals
z
MesoLighten ▼ Melanogenesis
Glutathione Kojic Vitamin C Azelaic acid
Complementary
Glycolic acid Tretinoin
MesoLighten Protocols Kojic acid (P) Azelaic acid (P) Vitamin C (P) Tretinoin (C)
Glutathione (P) Kojic acid (P) Vitamin C (P) Glycolic acid (C)
MesoLighten Injection sites & depths 1-2mm
Body z Localized
Fat
z Cellulite z Stretch
marks
Localized Fat
z LipoDissolve
= Injection Lipolysis
Localized Fat IAAL Injection Lipolysis
Mesotherapy
Deep 12mm PPC + DOC (PCDC) Hyaluronidase-CollagenaseArtichoke Intermediate 6mm (L-Carnitine-AminophyllineYohimbine- Artichoke)
2 - 4 mm L-Carnitine Aminophylline Pentoxifylline Effective complement
Phosphatidyl Choline (PPC) z An
antioxidant derived from soy lecithin. z PPC penetrates the adipocyte , breaks down fat . Dissolved fat is carried through bloodstream and excreted by kidneys and bowel.(P) z LipoDissolve + proper diet + Exercise.
Localized Fat/ Injection Lipolysis Lipolytic Enhancers: z Deoxycholate:
Bile salt(P). z L-Carnitine: Enhances both lipolysis and fatty acid oxidation(P) z Artichoke: Direct lipolytic (P) z Aminophylline , Caffeine & Xanthine(P) z Hyaluronidase & Collagenase: PPC enhancer Enzymes (C)
PPC + DOC z
Detergent Effects of Sodium Deoxycholate Are a Major Feature of an Injectable Phosphatidylcholine Formulation Used for Localized Fat Dissolution. Rotunda AM, Suzuki H, Moy RL, Kolodney MS. Dermatol Surg 2004;30:1001-8. Division of Dermatology, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California, USA.
Conclusions:
The phosphatidylcholine formula popularly used in subcutaneous injections for fat dissolution works primarily as a detergent causing nonspecific lysis of cell membranes. Our findings suggest that sodium deoxycholate is the major active component responsible for cell lysis.Thus,eliminating unwanted adipose tissue.
Localized Fat/ Injection Lipolysis Circulatory Enhancers: z Yohimbine:Alpha2-adrenergic Blocker. z Aminophylline &Pentoxiphylline: PDEI Drainage Enhancers: z Artichoke:Diuretic and stimulates lymphatic drainage
Localized Fat/ Injection Lipolysis Protocols Phosphatidylcholine(P) Deoxycholic Acid(P) Vitamin complex Alpha Lipoic Acid Amino Acids
Phosphatidylcholine(P) Deoxycholic Acid (P) Taurine Organic silicium
Phosphatidylcholine(P) Deoxycholic Acid (P) L-Carnintine Aminophylline Pantothenic Acid
LipoDissolve Injection sites & depths12mm
Cellulite z
Aesthetically cellulite is a problem consisting of the visual presentation of weakened and damaged fatty tissue and connective fibrous tissue in the form of bumps and dimples, commonly known as “orange skin”.
Cellulite
Treatment must act in two different ways: z on the fat (Lipolytic effect) z on circulation (Venotonic effect + Drainage)
Cellulite z Lipolytic:
L- Carnitine + Caffeine . z Venostatic: Rutin – Aminophylline –Pentoxiphylline. z Drainage: Artichoke.
Cellulite Protocols z z z z z z
L- Carnitine Aminophylline Pentoxiphylline Yohimbine DMAE Procaine
All are Principals
z z z z z z
L- Carnitine Aminophylline Pentoxiphylline DMAE Vitamin C Procaine
Stretch Marks The connective tissue, including collagen and elastin, becomes increasingly damaged until eventually causing the formation of stretch marks.
Stretch Marks Collagen Elastin Stimulating/ Restoring agents
Organic Silicium / Silorg z Centella Asiatica z Vegetal proteins + Fibronectin z
Firming agents z DMAE + Vitamin C z DMAE + Idebenone.
MesoStretch Marks Protocols Silorgamine = Silorg + DMAE z
z z z
Idebe = Idebenone + DMAE z
z z z
All are Principals
Centella Asiatica Fibronectin Vegetal Proteins
Vitamin C DMAE Silorg
Needle size
30/32 G x 4 mm z 30/32 G x 6 mm z 30/32 G x 12.7 mm z
MesoGuns
Meso Doctor Syringe Infusion Pump
Injection Techniques z PAPULE:
1 to 2mm, with bevel upwards z NAPPAGE: 2 to 4mm, angle of 30° to 60° z POINT BY POINT: deep injections, 4 to 12mm
Contraindications Pregnancy, blood thinners, IDDM, cancer patients, AIDS patients, coronary artery heart disease or heart dysfunction, People with arrhythmias, history of blood clots or strokes, autoimmune diseases or organ transplant recipients and skin conditions including: herpes & psoriasis.
MESOPORATION
z Mesotherapy
------ Non invasvive z No needles are required.
MESOPORATION A new complex process utilizes the skin's water based "channels" to allow ionic drug solutions to penetrate into the skin, via controlled "electroporation - like" electrical pulses.
MESOPORATION
MESOPORATION
MESOPORATION ADVANCED MOLE TRANSFER
AN
M
V AD
EN TS
For face and body treatment with electroporaction and dermoabrasion
CE
ST DM ED I C AL I N
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MesoLighten Injection sites & depths 1-2mm
MesoLighten Injection sites & depths 1-2mm
MesoLighten
LipoDissolve
LipoDissolve Injection sites & depths12mm
Cellulite
Cellulite
MesoCellulite Injection sites & depths 2mm
MesoCellulite
MesoStretch Marks Injection sites
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