Study
Principle Coordinator Investigator GlaxoSmithKline Dr Hramiak Sue Tereschyn TIDE
National Institute Dr Hramiak of Health ACCORD sanofi-aventis ORIGIN
Dr Hramiak
Description of Active End Date Study Thiazolidinedione Yes August intervention with 25, 2009 vitamin D to June evaluation 30, 2017 (TIDE). A multicenter, randomized, double-blind, placebocontrolled trial of a thiazolidinedione or placebo and of vitamin D or placebo in people with Type 2 diabetes at risk for cardiovascular disease. Marsha Driscoll Action to Control Yes November 2 Cardiovascular Risk Melissa 2000 to in Diabetes Geghring December Sue Tereschyn 31, 2010 Nancy Schmidt A multi-center, Yes April 25, international, 2003 to Sept 30, randomised, 2x2 2011 factorial design study to evaluate the effects of Lantus (insulin glargine) versus standard care, and of omega-3 fatty acids versus placebo, in reducing cardiovascular morbidity and mortality in high risk people with impaired fasting glucose (IFG), impaired glucose tolerance (IGT)
Bristol Myers Squibb CV 181014-150
Dr Hramiak
Novo Nordisk Pregnancy NN-304-1687
Dr Hramiak
Bristol Myers Squibb CV 181-057
Dr Hramiak
or early Type 2 diabetes mellitus: The Origin Trial (Outcome Reduction with Initial Glargine Intervention) Sue Tereschyn A multicenter, Yes randomized, double-blind, placebocontrolled, phase 3 trial to evaluate the efficacy and safety of saxagliptin (BMS-477118) in combination with metformin in subjects with type 2 diabetes who have inadequate glycemic control on metformin alone. Marsha Driscoll A randomised, Yes parallel-group, open-labelled, multinational trial comparing the efficacy and safety of insulin detemir (levemir) versus human insulin (NPH insulin), used in combination with insulin aspart as bolus insulin, in the treatment of pregnant women with type 1 diabetes. To assess efficacy Sue Tereschyn Yes of Saxigliptin when added to insulin monotherapy/or
September 2, 2005 to December 31, 2010
April 26, 2007 to December 31, 2010
March 10, 2009 to June 30,
insulin in combination with Metformin To assess efficacy of SGLT2 inhibitor on change in HbA1c Phase 2 study
2010
Hoffmann-La Roche Novalight
Dr Hramiak
Sue Tereschyn
Merck TECOS
Dr Hramiak
Marsha Driscoll
Trial Evaluating Cardiovascular Outcomes with Sitagliptin
sanofi-aventis GETGOAL-M
Dr Hramiak
Sue Tereschyn
Eli Lilly H80-CA-GWCE
Dr Hramiak
Marsha Driscoll
Thyroid Cancer Study
Dr vanUum
Dr vanUum
GLP-1 agonist Yes AVE0010 in paTients with type 2 diabetes mellitus for Glycemic cOntrol and sAfety evaLuation, on top of Metformin. Effect of Yes Exenatide on Abdominal Fat Distribution in Patients with Type 2 Diabetes Pretreated with Metformin. To study thyroid Yes
Hypothyroidism Study
Dr vanUum
Dr vanUum
Yes
2011
Thyroid Hormone Absorption Study
Dr vanUum
Dr vanUum
Yes
2010
Yes
2016
Yes
July 2010
DCCT/EDIC Michaels
Dr. J. Dupre, Dr. J. Mahon
Judy Harth
Dr Edmonds Dr. GwadrySridhar
hormone dose in patients with thyroid cancer To study thyroid hormone dose in patients with hypothyroidism To study thyroid hormone absorption and interaction by other drugs Epidemiology of Diabetes Intervention Study Study: Live Well, Connected (Health
Yes
April 21, 2009 to Mar 1, 2010
Yes
August 25, 2009 to December 31, 2016 September 16, 2008 to June 30, 2010
October 24, 2008 to June 30, 2010
2010
Technology Assessment and Implementation Program) To reduce insulindependent diabetics in the genetically at risk TRIGR The natural history of the development of type 1 diabetes To study Chromogranin A levels in patients with carcinoid (neuroendocrine) tumors To study Chromogranin A levels in volunteers taking proton pump inhitibors To study Hair Cortisol Levels in patients with adrenal insufficiency Fenofibrate in Polycystic Ovary Syndrome (PCOS)
TRIGR
Dr Mahon
Lynda Bere
TrialNet
Dr Mahon
Lynda Bere
The natural history of the development of type 1 diabetes
Dr vanUum
Dr vanUum
Chromogranin A Study
Dr vanUum
Dr vanUum
Hair cortisol in Addison
Dr vanUum
Dr vanUum
Fenofibrate in Polycystic Ovary Syndrome (PCOS)
Dr Joy
Lorraine Cauchi
Families fighting Diabetes Lawson Foundation Preventing childhood obesity
Dr McManus
Clinical Trial
2009
Dr M Mottola Dr McManus
Early intervention and first year postpartum for overweight and obese women using a twopronged familybased nutrition and exercise lifestyle intervention (NELIP), Clinical Trial, PI: Dr M Mottola
2008 to 2011
Yes
2016
Yes
2014
Future
2011
Future 2010
2010
Yes
2010
Yes
2011
Dr McManus
A Nutrition and Exercise Lifestyle Program (NELIP)
Dr M Mottola Dr McManus
Dr M Mottola Dr McManus
Vitamin D and Cytokine levels in women with and without gestational diabetes A Nutrition and Exercise Lifestyle Program (NELIP) for women with gestational diabetes, Prevention of excess body weight gain in pregnant women with GDM, Capacity-building and participatory research development of a communitybased Nutrition and Exercise lifestyle intervention program (NELIP) for pregnant and postpartum Aboriginal Women
2008 to 2010
2008 to 2010
2006 to 2009
