Alumni Connection

Volume XXVI, No. 1

A Legacy of Learning

TOP 10

First Annual Sones/Favaloro Program Draws Large Audience

for 2016

More than 200 Cleveland Clinic alumni and other attendees packed the

MEDICAL INNOVATIONS Each year, Cleveland Clinic’s Medical Innovation Summit concludes with a muchanticipated list of the top medical innovations for the coming year. More than 1,600 attendees converged on the Cleveland Convention Center in late 2015 for the 13th annual Innovation Summit, where the Top 10 Medical Innovations for 2016 were announced. From the rapid development of epidemic-battling vaccines to neurovascular stent retrievers that help stroke patients, the list includes game-changing technology, breakthrough drug therapies and practical public health initiatives. See the list on page 4, in order of anticipated importance.

Intercontinental Hotel and Conference Center in November at Cleveland Clinic’s main campus for the inaugural Sones/ Favaloro Scientific Program and Awards Presentation. Lars G. Svensson, MD, PhD (CARD/S’87), and Chair of the Sydell and Arnold Miller Family Heart & Vascular Institute, hosted the event, which is planned to be held annually. “It was all a great success,” Dr. Svensson says. “I think it’s very important to recognize those whose shoulders we stand upon and to examine the foundations of

the cardiovascular unit and the benefits patients have received from its research and care.” The program was named after two legendary Cleveland Clinic doctors whose work several decades ago helped to propel Cleveland Clinic to international status for heart surgery, Mason Sones, MD, and René Favaloro, MD, pioneers in coronary artery angiography and coronary artery bypass surgery, respectively. “Here was an operation commonly needed, that saved lives, relieved symptoms, and prolonged survival,” Dr. Svensson said of Dr. Favaloro’s trailblazing work. “The Continued on page 2

Continued on page 4 Dr. Norman R. Hertzer accepted his Sones/Favaloro Award during ceremonies held recently in Cleveland.

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Sones/Favaloro Program Continued from page 1

Lars G. Svensson, MD, PhD, and Chair of the Sydell and Arnold Miller Family Heart and Vascular Institute, welcomes a large audience to ceremonies honoring the first recipients of the Sones/Favaloro Emeritus Professorship Awards.

The Award Those presented with the Sones/Favaloro award received a statuette and a tie bearing an emblem of entwined hands. This emblem is from a sculpture by Auguste Rodin. Dr. Svensson said that because the hands come together, they can symbolize either a physician reaching out to a patient or the joining of professionals, representing teamwork.

Mark Your Calendars The Second Annual Sones/Favaloro Scientific Program, Reception and Awards presentation will be held on Friday, Nov. 18, 2016.

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result was a hospital building boom essentially funded by coronary bypass surgery, a great success for its time.” To honor the memories of Dr. Sones and Dr. Favaloro and salute the standout physicians who followed them, the Sydell and Arnold Miller Family Heart & Vascular Institute (HVI) honored three doctors whose contributions to medicine were extraordinary and exemplified talents including leadership, surgery, research, publications, presentations and going the extra mile for patients. The first recipients of the Sones/Favaloro Emeritus Professorship Awards are: Bernadine Healey, MD, (posthumous), whom Dr. Svensson lauded as one of the most influential leaders in healthcare in the last 50 years in the United States. She began her career as a cardiologist and Assistant Dean at Johns Hopkins, then went on to become Assistant Director for research and technology in the White House, followed by Director of Research at Cleveland Clinic. During that period, she was the principal investigator of a study comparing coronary artery bypass surgery with PTCA. Her career continued with appointments as Director for the National Institutes of Health, Dean of Medicine at Ohio State University and CEO for the Red Cross. She also was a Republican candidate for the U.S. Senate representing Ohio and was an advisor to three American presidents. Fred Loop, MD, (TS’70), (posthumous), who followed closely in the footsteps of Dr. Favaloro and perfected coronary artery bypass surgery. A major contribution was his paper (co-authored by Toby Cosgrove, MD, Bruce Lytle, MD, and Paul Taylor, MD), published in the New England Journal of Medicine, on the benefits of internal mammary artery bypass surgery. It is considered the gold standard for coronary

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artery bypass surgery today. After serving for 14 years as Chair of the Department of Thoracic and Cardiovascular Surgery, Dr. Loop was CEO from 1989 to 2004. He broadened the footprint of Cleveland Clinic, added eight regional hospitals and the Cole Eye Institute, the Taussig Cancer Institute, the Lerner Research Institute and the Lerner College of Medicine. Dr. Loop once said, “We must realize we are only the temporary guardians of this enterprise. Each of us is responsible for ensuring that the name Cleveland Clinic will always stand for the finest in healthcare and the best example of physician leadership.” Norman R. Hertzer, MD (GS’72, VS’75). Among his publications, he reported a study of preoperative coronary catheterization prior to elective vascular surgery in over 1,000 patients and conducted noteworthy research on combining coronary artery bypass surgery with carotid endarterectomy. He was a member of the Department of Vascular Surgery from 1976 to 2005, serving as Chair from 1989 to 1998. He also was President of the National Society for Vascular Surgery and an Associate Editor of the Journal of Vascular Surgery. Sudish Murthy, MD, PhD, new Chair of Thoracic and Cardiovascular Surgery and the evening’s emcee, presented other awards to a number of current HVI members for their contributions to medicine and patient care. Dr. Svensson offered a thank-you to Cleveland Clinic’s Alumni Association for its help in preparing for the event. Mindy Stroh, Alumni Association Director, said, “We are happy to assist with events such as this, where alumni can come together to celebrate, catch up, share experiences, learn what’s happening on main campus or continue their medical education through seminars and conferences.”

clevelandclinic.org/alumni

Dr. Hertzer Recalls His Award Colleagues Norman R. Hertzer, MD, was on hand for the awards ceremony and was invited onstage to offer personal remarks. Here is an excerpt: “I always have been honored to be a Cleveland Clinic surgeon, but never more so than to receive this award, together

Dr. Norman R. Hertzer, holding award, is congratulated by his colleagues (from left) Dr. Lars G. Svensson, HVI Chair, Dr. Brian G. Donley, Chief of Staff, and Dr. James B. Young, Executive Dean of the Cleveland Clinic Lerner College of Medicine.

with Fred Loop and Bernadine Healy. The world does not seem the same to me without them – it certainly is a lot less smart. “I doubt anyone will ever be able to match Bernadine’s professional resume – but the thing that I most fondly remember was her extraordinary personal grace. Bernadine was eager to put you at ease the moment she met you, and her smile could embrace you all the way across the room. “Fred was the most impressive man I ever met. He became one of the world’s preeminent heart surgeons, but I am convinced he would have excelled at anything he ever tried, at any time in history. “It’s just impossible to view the current main campus, and, perhaps his proudest achievement, the Lerner College of Medicine, without thinking of how much Fred’s uncanny vision as the CEO was responsible for them. “It is my distinct privilege to receive the first Sones/Favaloro Award together with both Fred and Bernadine.” Afterward, Dr. Hertzer told Alumni Connection he always has been proud of being at Cleveland Clinic, working hard and helping those in his charge. “It’s been a wonderful career, made all the better by working with such talented colleagues,” he said. “ I feel great whenever I see the same pride in the faces of the young Cleveland Clinic staff of today. Perhaps they’ll discover what I did: When we speak on behalf of Cleveland Clinic, people listen.”

Alumni, Others Tune in on Latest Developments in Heart Medicine What do you present to more than 250 visiting alumni and others who may not be up on the latest developments on the main campus? You give them a highlight tour, let them look in on a medical operation in progress and have them hear from a dozen Cleveland Clinic experts on the latest innovations in their fields of expertise within the Sydell and Arnold Miller Family Heart & Vascular Institute. On one tour was Gary H. Dworkin, MD (CATS’92), Immediate Past President of the Alumni Association. With him were several guests, including retired Professor Jaap Bredée, MD (TCS’76), a Cleveland Clinic-trained cardio-thoracic surgeon visiting from the Netherlands, and his guest, Dr. Niels van der Kaaij, a young cardio-thoracic surgeon from the University Medical Center Utrecht. “Alumni Association Director Melinda Stroh, was able to arrange a 90-minute tour, led by Gregory P. Borkowski, MD (IM’74, DR’79), Chair of the Imaging Institute,” Dr. Dworkiin says. “Dr. Borkowski led us through the MRI, CT, Interventional and GI radiology suites and included discussions with us about patient scheduling and throughput, technology assessment and equipment purchasing, as well as numerous design decisions he and his team were required to make. He also covered plans for expansion of imaging services at Cleveland Clinic Florida in Weston.



Distinguished guest at the Sones/Favaloro Awards Ceremony was Dr. Jaap Bredée (left), and his guest, Dr. Niels van der Kaaij. They received a tour of of the Imaging Institute with Alumni Association Immediate Past President Dr. Gary H. Dworkin (right).

“In addition to the fresh and progressive design features we saw, it also was apparent throughout our tour that Imaging Services had a small army of technicians, nurses and other caregivers unlike any I had ever seen in a hospital imaging department,” Dr. Dworkin said. “I came away from the tour with the realization that a colossal investment was made. And, even though this investment was directed at many levels of service, it obviously was done with an unwavering focus on our patients and their families.”

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Top 10 Medical Innovations Continued from page 1

#1 Vaccines to Prevent Public Health Epidemics The No. 1 spot goes to the scientists, physicians and public health officials who are developing safe, efficient and effective vaccines faster than ever to prevent disease epidemics. These efforts were given new urgency by the 2014 Ebola epidemic in Africa and bacterial meningococcal (Meningococcal B) outbreaks in the United States. In both cases, physicians, scientists, companies and government agencies worked at unprecedented speed to develop new vaccines and move them from laboratories to clinical testing in large populations.

#2 Genomics-based Clinical Trials Genomics-based clinical trials are speeding the development of new targeted therapies. Potential research participants are sorted by genetic criteria and matched with an experimental therapy that targets the particular molecule associated with their disease. Genetic profiling reduces trial enrollment time and increases the chance that participants will benefit from the therapy being studied.

#3 Gene Editing using CRISPR Not long ago, the ability to alter DNA of any organisms, including human embryos, was an idea found only in the pages of a science fiction book or on a movie screen.  However, now, a new technique, called CRISPR, is proving not only that this is possible, but that it actually can be accomplished fairly easily and at a modest cost when compared with early gene-editing attempts. As a result, it is being adopted by labs everywhere. 

#4 Water Purification Systems for Prevention of Infectious Diseases In the developing world, it is not uncommon to see sewage in the streets with nowhere to go but into the local drinking water. This situation contributes to more than 10 percent of the disease burden on the entire world. An estimated 700 million or more people in the world are drinking unsafe water every day, and according to the World Health Organization, more than a million children under the age of 5 years old in developing nations die each year because of contaminated water and poor sanitation. 

#5 Cell-free Fetal DNA Testing The market in pregnancy wellness has grown to almost $2 billion as new parents increasingly invest in books, diets, and yoga classes dedicated to ensuring that their babies will be born healthy. The potential for genetic diseases including Down’s Syndrome, Edwards Syndrome, and Patau Syndrome, however, is not in the mother’s control and therefore can cause a great deal of stress, in part because of vague and uncertain results of the current types of tests available

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Top 10 Medical Innovations Continued from page 4

#6 Cancer Screening via Protein Biomarker Analysis To understand the risk of cancer, scientists for years have focused narrowly on changes in the concentration of a single protein in biological fluids such as blood or urine or, alternatively, on genetic mutations. However, relatively poor sensitivity, specificity and predictive value generally limit the diagnostic accuracy and clinical utility of these tests.  Protein biomarker analysis could make a difference in determining and addressing a patient’s risk. 

#7 Naturally Controlled Artificial Limbs Numerous innovations in prosthetics over the years have mimicked natural movement and provided a large boost to quality of life for amputees and individuals who are paralyzed. But with over 6 million people paralyzed and 100,000 Americans living with an upper-arm amputation, a large patient population is paying close attention to this innovation, which could revolutionize the use of prosthetics.

#8 First Treatment for HSDD Sexual desire is different from sexual performance. While several medications address male sexual dysfunction, none relate to loss of sexual desire in women. Until now. In 2015, the FDA approved flibanserin, the first medication designed to treat female hypoactive sexual desire disorder (HSDD), or loss of sexual desire in premenopausal women.

#9 Frictionless Remote Monitoring The wearable technology market is skyrocketing.  A recent study estimated that 20 percent of American adults are wearing a device that collects data on everything from exercise and sleep habits to heart rate and blood pressure. The wide adoption has led to excitement about a potentially healthier population in coming years. In addition to wellness, there are millions of sick patients who can benefit from wearables that are monitoring data of every breath, bead of sweat, or chemical change in the body. In many cases, how medical professionals react to these detected alterations can mean life or death. 

#10 Neurovascular Stent Retrievers The immediate hours after an ischemic stroke are critical. The clot that occurs in a blood vessel must be removed within three to six hours in order to prevent long-term disability, brain damage or death.  For years, the only FDA-approved treatment for removing clots has been a tissue plasminogen activator, or tPA.  The medicine, delivered intravenously, travels to the clot and dissolves and restores blood flow to the brain. When an occlusion forms in a major vessel, however, tPA is effective in less than a third of all patients. For years, scientists have been seeking reinforcements that could aid tPA in eliminating main-stem clots as quickly and safely as possible. The result is the stent retriever.



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PROFESSIONAL DEVELOPMENT AWARDS We thank our alumni for contributing annually to both the Education Institute in support

Other 2015 recipients included:

of eligible residents and fellows in graduate medical education and to the eligible Cleveland Clinic Lerner Research Institute post-doctorate fellows. Funds are used for travel to medical meetings, forums and seminars in support of their vocations.

Kelsey Potter, PhD, Mentor: Ela Plow, PhD, Department of Biomedical Engineering, Lerner Research Institute. Dr. Potter selected the oral presentation, “Enhancing cortical representational plasticity with non-invasive direct current stimulation to accelerate upper limb recovery in quadriplegia.” The America Society of Neurorehabilitation and the Society for Neuroscience, in Chicago, Illinois, was her chosen medical meeting. With her award, she said: “I gained valuable information regarding the current state of the field and exciting future directions — many of which I am currently incorporating into grant applications and future manuscripts. Therefore, I am extremely thankful for the Alumni Association’s support of this award.” 

Praveena Thiagarajan, PhD, Mentor: Thomas McIntyre, PhD, Department of Cellular and Molecular Medicine. Dr. Thiagarajan studies “Interrogating the cellular heterogeneity and self-renewal in triple negative breast cancer.” She chose to attend the Mammary Gland Biology Gordon Research Conference in West Dover, Vermont. She said, “Attending the Gordon Research Conference was an enriching experience as it offered a wonderful platform for me to engage with experts and be able to present and exchange novel ideas and learn about the latest concepts and techniques in the field. The conference is designed to promote the careers of young scientists.”

Cassandra Bilogan, PhD, Postdoctoral Fellow, Mentor: Takuya Sakaguchi PhD, Department of Stem Cell and Regenerative Medicine, Lerner Research Institute. Selected poster presentation, “Endoderm Lineages in Development and Disease”, Keystone Conference, Keystone, Colorado.

Chia-Feng Liu, PhD, Postdoctoral Fellow, Mentor: Veronique Lefebvre, PhD, Department of Cellular and Molecular Medicine, Lerner Research Institute. Selected oral presentation, “SOX9 and SOX5/SOX6 interact genomewide to implement the chondrocyte differentiation program,” Gordon-Kenan Research Seminar on Cartilage Biology and Pathology, Galveston, Texas. Continued on page 7

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PROFESSIONAL DEVELOPMENT AWARDS Continued from page 6

Amina Abbadi, PhD, Postdoctoral Fellow, Mentor: Vincent Hascall, PhD, Department of Biomedical Engineering, Lerner Research Institute. Selected for a Plenary Session Short Talk, “HA in Inflammation and Signaling,” International Society for Hyaluronan Sciences, Florence, Italy.

Yan Wang, PhD, Postdoctoral Fellow, Mentor: Edward Maytin, MD, Department of Biomedical Engineering, Lerner Research Institute. Selected Oral Presentation, “The role of Hyaluronan and its synthesizing enzymes in regulating skin wound healing and epidermal carcinogenesis.” International Society for Hyaluronan Sciences, Florence, Italy.

Lindsey PierceFriedrich, PhD, Mentor: David Serre, PhD, Genomics Medicine Institute, Lerner Research Institute. Selected oral presentation, “Assessment of Population Stratification and Complexity of Infection in Cambodian Plasmodium Vivax by High Throughput Sequencing,” American Society of Tropical Medicine and Hygiene, New Orleans, Lousiana.



Sumeda Nandadasa, PhD, Mentor: Suneel Apte, PhD, Department of Biomedical Engineering, Lerner Research Institute. Selected oral presentation, “Sculpting the mammalian embryo: Matrix Metalloprotein-ases.” Gordon Research Conference, Newry, Maine.

Qi Xie, PhD, Mentor: Jeremy Rich, MD, PhD, Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute. Workshop: The Genome Access Course, Cold Spring Harbor Laboratory, New York Genome Center, New York City, New York.

Arnab Basu Experimental Therapeutics Fellow, Taussing Cancer Institute, was awarded funds toward his attendance at the American Society of Hematology Annual Meeting to present his award-winning research, “Platelet Activation and Aggregation in Patients with Advanced Adenocarcinoma Undergoing Chemotherapy: Correlation with a Validated Venous Thromboembolism Risk Score.”

Youran Zou (PGY-4, Anatomic and Clinical Pathology) was awarded funds toward the costs of an external rotation at Massachusetts General Hospital in Gynecologic Pathology.

Jeff Mullin (PGY-6, Neurosurgery) was awarded $800 toward the cost of attending the Winter Clinics for Cranial and Spinal Surgery in Colorado.

Valery Vilchez PGY-1, General Surgery, was awarded funds toward the cost of attending the International Hepato-Pancreato Biliary Association meeting in Sao Paola. As an intern, she does not have GME-sponsored funding: so this award will enable her to attend the meeting.

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ALUMNI LIBRARY RENAMED IN HONOR OF DR. FLOYD LOOP In late 2015, Toby Cosgrove, MD, Cleveland Clinic CEO and President, announced that the Alumni Library would be renamed in honor of Floyd D. Loop, MD (TS’70), legendary heart surgeon and former CEO of Cleveland Clinic who died last year. Now, everyone entering the library can see the name, “The Floyd D. Loop Alumni Library,” featured prominently above the doors. “Those of us who were here in the Loop years certainly remember him as a good library user, for all sorts of things, and naming the Alumni Library for him is definitely fitting,” says Gretchen Hallerberg, Director of Library Services. Rich history Although the library on the main campus has been a valuable asset to Cleveland Clinic, few people know its history. Initially, it was on the top floor of the original Cleveland Clinic building, surrounded by the Art and Photography Department, editorial offices, a board room where the founders had meetings, offices for administrators and bookkeepers, and founder George Crile, MD’s, biophysics laboratory. In 1964, the library moved to the fourth floor of the new Jennings Education Building. Alumni Affairs was part of the Education Institute then, so the library often was included in its monthly discussions.

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At one of the meetings, an Alumni Board member asked, “If the alumni made a substantial contribution, do you think the library could be named for them?” This is when alumni began making pledges. The success was overwhelming — the alumni pledged $5 million over three years and met the fundraising goal early. In April 1999, the library officially became the Alumni Library and moved to the Lerner Research Institute building, occupying two floors. A great service Throughout the years, the library has been reconfigured to better serve everyone. It now occupies one floor instead of two because so many resources are online instead of in print. In 2015, library users downloaded nearly 1.3 million articles from some 45 publishers. Alumni are welcome to visit Cleveland Clinic’s Alumni Library in person and use computers to access all electronic resources. Library staff is on hand to complete literature searches and provide copies of articles from print journals. The Alumni Office offers parking validation to Alumni who visit the library. For details, please email [email protected].

clevelandclinic.org/alumni

SHADOWING DR. SCHMITT

(Editor’s note: Cleveland Clinic’s Steven K. Schmitt, MD (IM’91, ID’94), recently was chosen as the man to “shadow” by medical students interested in a career in infectious disease. His participation was part of the AMA Wire’s ® “Shadow Me” specialty series. Here are his insights on life within his specialty.) Steven K. Schmitt, MD

Years in practice: 21 A typical week in my practice:  If you like diversity in your career, the typical Infectious Disease (ID) day is for you. In a typical day, I provide inpatient and outpatient care. I have the privilege of participating in the education of students, residents and fellows. I have the opportunity to help mold the future of healthcare by administration at the system level in Cleveland (I am involved in professional development of physicians) and advising/policy work for professional societies, primarily the Infectious Diseases Society of America. And, yes, it is not uncommon for all of these elements to be part of the same day. In a typical week, I will attend on either a general infectious diseases consultation service or a bone-and-joint infection consultation service. Typical work weeks are 50 to 80 hours — less when not attending on an inpatient service, and more when covering a weekend.  The most challenging and rewarding aspects of caring for patients in ID: ID specialists often are asked to be medical detectives, evaluating nonspecific symptoms such as fever among returning travelers or hospitalized patients. In many cases, the patient has been seen by several physicians prior to consultation with an ID specialist. In addition, we often are asked to consult regarding postsurgical infections and spend a large amount of time educating the patient and family.   



The most rewarding part of the specialty is using our detective skills to diagnose and treat an infection that others may not have considered, returning the patient to health. Four adjectives that describe the typical physician in ID: Collegial, compulsive, integrative, communicative. How my lifestyle matches or differs from what I envisioned in med school:  I have had “the fever” for ID since childhood and had a pretty good preview of the lifestyle of general ID consultation from working in a department for two years prior to medical school.  What I had not counted on was the evolution of ID practice to include sub-subspecialties, such as bone and joint infections. In addition, I had not fully appreciated that ID training and practice entail a level of systems thinking that lends itself well to care transitions, epidemiology, healthcare administration and public health leadership.  Three aspects every ID physician-intraining should have but for which they won’t be tested by the board exam:  Compulsivity, collegiality and being communicative. One question physicians in training should ask before pursuing ID: Do I want to build the skills to lead in diverse domains, such as clinical care, medical education, epidemiology, public

health, research and health systems administration? Three books every medical student interested in ID should read: • Microbe Hunters, by Paul de Kruif (this book made me an ID specialist at age 13).  • The Hot Zone, by Richard Preston • The Plague, by Albert Camus Six quick tips I’d give students who are considering ID:  1. Seek out great mentors and mentor others. 2. Develop good work habits, such as taking the patient’s history and looking at imaging studies yourself. Also talk to patients, family and colleagues directly; there is no substitute for direct communication. 3. Finish what you start. 4. Network relentlessly. 5. Treat everyone with respect. 6. Take care of yourself, your family and your colleagues first. Good health and good relationships set the groundwork for a great life in medicine. Want to learn more about your specialty options?  Find additional insights from physicians in adolescent medicine, physical medicine and rehabilitation, radiology, and orthopedic surgery in the AMA’s “Choosing a Medical Specialty” resource guide (member log-in required.).

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Cleveland Clinic: In the News Cleveland Clinic officials have signed a long-term lease on a six-story office building in London’s West End, where it will open a new healthcare facility as part of its effort to offer its services internationally. Cleveland Clinic will lease the building at 33 Grosvenor Place, a 198,000-square foot structure. Cleveland Clinic is evaluating what kind of health care services it will provide there. “Cleveland Clinic has become a national leader in health care in the United States, and we are committed to reinvesting in our mission, as well as expanding locally, nationally, and internationally,” said Cleveland Clinic CEO and President Toby Cosgrove, MD Marc Harrison, MD, Cleveland Clinic’s Chief of International Business Development, will lead the planning process.

Akron General, now part of Cleveland Clinic, has broken ground on a $43 million emergency department that is three times larger than its present facility.

Akron General, now part of Cleveland Clinic, has broken ground on a $43 million emergency department that is three times larger than its present facility. The two-story building in downtown Akron will add 60,000 square feet to the campus. The facility replaces Akron General’s 19,000-square-foot emergency facility and includes four trauma rooms, a specialized area for sexual assault victims, an expanded behavioral health unit and an imaging department with radiology equipment. The emergency department also will include an urgent care area for non-emergency patients, as well as an area in which patients with contagious diseases could be quarantined. The hospital currently treats about 56,000 emergency room patients each year, and the new department will be able to accommodate up to 75,000 annually.

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Cleveland Clinic Abu Dhabi has officially opened. His Majesty King Mohammed and His Highness Sheikh Mohamed bin Zayed presented an award of appreciation to Marc Harrison, MD, Cleveland Clinic Abu Dhabi’s former CEO, now Cleveland Clinic’s Chief of International Business Development. On Dec. 3, Cleveland Clinic Abu Dhabi celebrated its official inauguration with His Majesty King Mohammed VI of Morocco, His Highness Sheikh Mohamed bin Zayed Al Nahyan, Crown Prince of the Emirate of Abu Dhabi and Deputy Supreme Commander of the United Arab Emirates Armed Forces. The celebration was held in conjunction with United Arab Emirates’ National Day, which is indicative of Cleveland Clinic Abu Dhabi’s significance in establishing a world-class healthcare sector in the Emirate of Abu Dhabi and the United Arab Emirates. Toby Cosgrove, MD, CEO and President of Cleveland Clinic, with the leadership of Mubadala, an investment and development company, Cleveland Clinic Abu Dhabi’s shareholder, addressed the audience on this occasion. Your Living Room is the New Waiting Room. Toby Cosgrove, MD, CEO and President of Cleveland Clinic, recently told Health Data Management about what he envisions as the smaller, more-focused, more-specialized hospital of the future. They will be more human, too, he says. A rapid acceleration in biomedical science and computer power will fundamentally change hospitals and hospital workers by mid-century, he predicts. Routine health care, such as outpatient surgery and treatment of chronic disease, already is moving closer to patients. By 2050, not every hospital will implant a pacemaker or deliver babies, he says. Instead, they will provide hyper-specialized treatment and care. Hospital workers, however, will be less specialized and able to treat a wider array of medical conditions. Aided by new technology, technicians increasingly will provide care. In addition, caregivers will rely on supercomputers, such as IBM’s Watson, which recently began medical training at institutions including Cleveland Clinic. Watson helps deliver faster and more accurate diagnoses and treatment options.

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Cleveland Clinic: In the News Continued from page 10

“The greatest change, I hope,” Dr. Cosgrove says, “will be a better doctor/patient connection. Yielding more responsibilities to technicians and supercomputers will require doctors to develop and deploy their most human skills: empathy, creative thinking and relationship building. Because it’s all about caring for people—and people feeling cared for.” Cleveland’s Cavaliers professional basketball team members, put a full-court press on the hallways of the Cleveland Clinic on their off day recently when all the players visited children in the hospital. Some patients may be too young to remember seeing

It was the Cleveland Cavaliers on hand for a special hello for children in the hospital recently. From left, they are: Iman Shumpert, James Jones, Matthew Dellavedova, LeBron James and Anderson Varejão.

the Cavs players dipping their heads to enter doorways of rooms to distribute team T-shirts, but for sure, their parents are unlikely to forget. Players posed for group photos, drew tired children out of their shells, and, in general, raised the level of cheerfulness to match their heights. Doctors, nurses, and staff also pressed against the hallway walls to let Cavs players and their entourage pass by, and they enjoyed seeing the players interact with the young patients. The new Cleveland Clinic Rehabilitation Hospital in Avon, Ohio, has opened. It is a joint venture between Cleveland Clinic and Select Medical, expected to employ about 200 employees. The 60-bed adult inpatient rehabilitation hospital next to Cleveland Clinic’s Avon medical campus offers rehabilitation treatment for patients with complex neurological, medical and musculoskeletal disabilities. Attorneys for the city of Lakewood, Cleveland Clinic and Lakewood Hospital Association have reached an agreement regarding the future of the hospital. The parties have been talking since January about a proposal to close Lakewood Hospital and open a Cleveland Clinic family health center and 24-hour emergency room in its place, in the face of declining admissions.



Authors Corner

Dr. Graham Writes of Putting Ideas to Work Thomas J. Graham, MD, renowned hand surgeon and former Cleveland Clinic Chief Innovation Officer, recently accepted a leadership post with Lake Nona Medical City, near Orlando, Florida. But before leaving for his new position, he put the finishing touches on his latest book, Innovation the Cleveland Clinic Way: Transforming Health by Putting Ideas To Work, published by McGraw-Hill. Dr. Graham says his book provides a blueprint for businesses and organizations– regardless of industry or size — that will help them create a culture of innovation and discovery. He draws on his own professional experience, exploring how to find time and resources that will permit innovation, even in an environment of day-today pressures and responsibilities. The book covers ways to keep everyone striving toward new discoveries, why creativity is overrated and collaboration is not, and many other topics. Cleveland Clinic Innovations, the commercialization arm of Cleveland Clinic, has helped launch more than 75 companies and executed more than 500 licenses on medical devices and techniques since 2000. Dr. Graham’s book is available at clevelandclinic.org/ clevelandclinicway.

ALUMNI CENTENARIANS Happy Birthday to those Cleveland Clinic alums who have reached ­— or surpassed — their 100th birthdays! Our congratulations, admiration and best wishes. The Cleveland Clinic Alumni Association. Dr. Herschel L. Browns (IM’49): 101 years old on Jan 16. Dr. William L. Proudfit (IM’43): 102 years old on Feb 16.

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TEAMWORK HELPS DOCTOR WHO FELL ON MOUNTAIN RUN

Dr. Jack Andrish, an avid hiker, had a serious fall recently, but professional teamwork came to his aid.

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hen Jack Andrish, MD (S’71, ORS’76), retired in 2013 after 38 years on Cleveland Clinic’s staff, his colleagues and friends knew that he wouldn’t be sitting in a rocking chair. The 71-year-old pediatric orthopaedic surgeon is known for his participation in distance-running events. Last year was no exception. For the 13th time, he ran the JFK 50 Mile, the nation’s oldest and largest ultramarathon. The course winds through the Appalachian Mountains in Maryland, from Boonsboro to Williamsport, partly along the famed Appalachian Trail. After about 12 miles, Dr. Andrish says, he was having “a nice time running the ridge line” when he tripped over a root and landed hard on his left hip, directly on a rock. In a thank-you letter to the team involved in his care after the fall, he describes his experience: “I guess my 13th JFK was an unlucky number for me. Turns out, I broke my hip with that fall. But from then on, I was well taken care of by a series of volunteers, some from Cleveland Clinic, some not. “First were two men who had camped that night about 100 yards from where I fell. They picked me up and off the trail and sat me on a log. They put up with my fussing that “it’s only a muscle” and warmed me up with coffee and a cookie. They were so kind, and I wish I had recorded their names. “About two-and-a-half hours later, two different groups arrived. One team of two EMT’s arrived on a Gator from one direction about the same time that two volunteers on ATVs arrived from another direction. After determining that our best choice was for me to sit on the back of an ATV, we proceeded on a two-hour bushwhack down the mountain. Fortunately, they had tools that included a chain saw for clearing the trail. Straddling the back seat of an ATV with a broken hip sounds like cruel and unusual punishment, but it wasn’t. The ‘driver’ was so considerate and made every bump as smooth as possible. “When we finally got off the mountain, I was transported to the Meritus Medical Center in Hagerstown. While in the emergency room, I was expertly evaluated and cared for. On Sunday I was flown home to Cleveland Clinic, where I received exceptional care. Monday, my hip was stabilized with a couple of pins and a plate. Tuesday, I was discharged home.” Dr. Andrish says his biggest regret is that he didn’t catch the names of all of the people who cared for him during his ordeal. He is grateful that even though he is retired, he still is part of an organization that takes care of its own, which he says is “one of our greatest strengths.” “Please extend my sincere appreciation to the assortment of caring and expert volunteers and professionals who facilitated the great care I received,” he writes. “Everyone — from the clerical to the technical to the medical professionals — performed with efficiency, efficacy and empathy. I could not have hoped for more (except, perhaps for a diagnosis of ‘it’s only a muscle’ rather than an intertrochanteric hip fracture).”

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The Charitable IRA Rollover is Permanent Plan now and plan for the future. No more last-minute or end-of-year speculation. The PATH Act, signed by President Barack Obama on Dec. 18, 2015, has made the Charitable IRA Rollover permanent. Individuals may make a charitable gift by transferring an income tax-free distribution directly from their IRAs to a qualifying charity. What are the requirements of an IRA Rollover? • You must be 70 ½ years old, or older • You may make annual gifts of up to $100,000 • Your distribution must be made directly to a qualified charity • Your gift is outright (tax-free rollovers to a planned gift such as a charitable gift annuity or a charitable remainder trust do not qualify)

How This Will Benefit You • If you are taking required minimum distributions from your IRA • If you usually contribute up to half of your adjusted gross income to charity • Whether you itemize or take the standard deduction • If you do not need the income from your IRA or if the income will substantially increase your income taxes. • Because the charitable distribution counts toward minimum required distributions • Because you may make pledge payments with a charitable IRA rollover (no out-of-pocket expense) Additional Points to Consider • It is likely that sometime in 2016 the State of Ohio also will pass conforming legislation to exclude such distributions from Ohio income tax consequences

• Distributions cannot be made to donor-advised funds, supporting organizations, private foundations, charitable remainder trusts, or charitable gift annuities Remember, because taxes have not been paid on the IRA contributions and will not have to be paid on the distribution to charity, a charitable IRA rollover gift does not qualify for a charitable deduction. If you have any questions or would like to learn how you can make a planned gift to Cleveland Clinic, please call Melinda Stroh, Director of Alumni Relations, at 216.444.2487, or send an email to [email protected].

VELOSANO RAISES $3 MILLION FOR CANCER RESEARCH This past July, nearly 1,300 cyclists from 28 states rode in VeloSano, pedaling more than 69,000 miles and raising $3 million to support cancer research at Cleveland Clinic. Thanks to VeloSano’s 913 volunteers and 40 event partners, every dollar raised by riders and virtual riders goes to cancer research and ultimately benefits patients. The third annual VeloSano weekend is scheduled for July 29–31, 2016. Registration opened in January. LEARN MORE AT VELOSANO.ORG.



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Frank E. Bunts, MD

George W. Crile, MD

William E. Lower, MD

John Phillips, MD

LOOKING BACK

HAPPY 95TH — AND COUNTING In just five years — Feb. 5, 2021 — Cleveland Clinic will reach a milestone, marking a century since its founding. In that time, Cleveland Clinic has become world-renowned for many achievements. A few of these are: • Pioneering work in hypertension and diabetes research and patient care • Breakthroughs in cardiovascular disease and surgery, including valve repair and bypass surgery • Leading-edge cancer research and treatment • Innovations in treating neurological disorders, such as deep brain stimulation for Parkinson’s disease Cleveland Clinic was founded on Feb. 5, 1921.

• Advancements in orthopaedics and the field of sports medicine • Groundbreaking work in transplantation, including lung, heart and kidney, as well as face transplants

There is still more to celebrate. The organization continues to perform in accordance with its unique model: the cooperative spirit of group practice to better treat the patient. Cleveland Clinic has established an international reputation for leading the way in medical research, education and patient care and for finding ways to make Cleveland Clinic has procedures safer and better and established an international more accessible to more people. In reflecting on Cleveland Clinic’s reputation for leading the way past, the Cleveland Clinic Alumni in medical research, education Association is seeking to focus on and patient care. the institution in a new way. How about highlighting the lesser-known stories of Cleveland Clinic’s past? Or touching on some anecdotes and facts that even some of the longtime staff never saw,

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didn’t know of, or would be surprised by? We think it is in the details that a true, full and rich picture of the overall organization can be found. By highlighting these unique stories, we also will honor the contributions of everyone who has made this institution what it is today. For example: While heart transplants seemed to make all the news, did you know the world’s first successful larynx transplant was done here, too? Who was our first female staff member? With the expert help of our partners in the Archives department, we will answer those questions for you, and more, through our celebratory series of stories, “Looking Back,” that we’ll publish in future issues of Alumni Connection.” We will publish 15 issues of Alumni Connection between now and Cleveland Clinic’s 100th birthday. Each will feature a “Looking Back” piece. We’ll have a lot of looking back to do between now and 2021!

We hope that you will enjoy taking this journey with us. By the way, if you have a reminiscence or little-known fact that you’d like to propose for mention in “Looking Back,” please contact Alumni Association Director Mindy Stroh at [email protected].

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Centennial Legacy Society Promotes Philanthropy The Cleveland Clinic family began with our founding physicians, Dr. George Crile, Dr. Frank Bunts, Dr. William Lower, and Dr. John Phillips. These four visionaries set out to develop an integrated group practice in which diverse specialists would be able to think and act as one. Their common goals in planning, commitment to their work and willingness to invest personal resources guaranteed the success of the new institution. Our founders thus became Cleveland Clinic’s first philanthropists. A nonprofit organization, Cleveland Clinic’s mission since its founding is to provide better care of the sick and improve patient care through research and education. Philanthropy helps Cleveland Clinic to better serve patients and advance education and training of students, residents and fellows. In celebration of our 100th year, the Centennial Legacy Society wishes to honor and celebrate Cleveland Clinic alumni who have given $5,000 or more during the Power of Every One Centennial Campaign through 2021. Alumni gifts will go toward Professional Development Grants in the Education Institute and Lerner Research Institute, as well as the Alumni Association’s Legacy Project (which includes establishing permanent space to highlight Cleveland Clinic’s history); Lerner College of Medicine student scholarships, and research, training and development programs.

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READERS WRITE

From Mummies to Medicine Editor, I am a second-year medical student at Cleveland Clinic Lerner College of Medicine and a grateful recipient of an Alumni Association Scholarship. I am writing you to thank you for the generous scholarship and to tell you what an immense impact it will have on my experience. I was born and raised in a nearby west-side suburb and have called Cleveland home for as long as I can remember. Growing up, I always had a strong interest in solving puzzles and mysteries. Naturally, my interest in science began early on. If you talked to me 20 years ago, I would tell you that unlike many of my teammates who wanted to become NHL hockey players, I wanted to become a forensic scientist, specializing in solving ancient mysteries involving mummies. However, I soon realized the budget of a 5-year-old was likely insufficient for travel to Egypt, and I began exploring more practical scientific opportunities a little closer to home. As I did this, I began to recognize my interest in and passion for applying science to help others. My medical career started at age 16 in Parma Hospital’s Emergency Department, where I would volunteer to clean beds, take visitors back to their loved one’s room, grab patients some extra blankets, and occasionally get to observe patient care. Soon, I was hooked on medicine. My excitement and passion for medicine grew as I received a high school internship position at Cleveland Clinic, where I got to design my own summer research project in the emergency department, participate in resident workshops and learn from leaders in the field. I realized that in addition to my love of medicine, I very much enjoyed critical thinking and innovative aspects of research. The internship program is also the reason that I heard about the Lerner College of Medicine early on, and I vividly remember the excitement on learning that there was this incredible school where you didn’t have to choose between medicine and research.

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After attending the University of Dayton as a premedical and German language student and increasing my interest in medicine (through working as an EMT) and research (through multiple basic science projects in Dayton and Germany), my high school dream of attending the Lerner College of Medicine became a reality. I was elated to be able to freely pursue my wide variety of interests and work in the community that is my home. Building on my previous experiences, I have been able to explore my passions in emergency medicine and have even expanded my interests to include healthcare delivery systems. In terms of emergency medicine, this involves asking the questions, “why do some patients use the ED for primary care?” and “how can we get patients the longterm care they need instead of treating their acute issues only when they become out of control?” Thus, my research interests now include “hotspotting,” a data-driven process that identifies high-utilizers of the healthcare system and uses a relationship-based model to assess where the current healthcare system is not meeting their needs, and designing interventions to reduce the frequency of ED visits/inpatient admissions and improve the patient’s quality of life. Moving forward in my career, I aspire to continue following and integrating my diverse interests with the goal of improving the emergency medicine system and providing high-quality care for patients in my hometown and across the world. The Lerner College of Medicine already has molded me to become an innovative, compassionate, team-oriented physician-investigator and I look forward to having the opportunity to share these strengths with the city I love the most. Thank you for your recognition of my efforts as a Lerner College of Medicine student and the generous scholarship. I will work tirelessly to continue giving the strengths and talents I have cultivated there to our community. Alexander J. Ulintz

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READERS WRITE Continued from page 16

How a Bond Formed Between an Overseas MD and ‘His’ Cleveland Clinic (Editor’s note: Netherlands Professor Jaap Bredée, MD, trained at Cleveland Clinic many years ago, but his pride in his affiliation remains strong. That is why he traveled thousands of miles to honor his teachers at Cleveland Clinic and attend the Sones/Favaloro scientific program. Poignantly, he brought with him a young cardio-thoracic surgeon from his country, Niels van der Kaaij, MD, to learn about Cleveland Clinic. Who knows? Perhaps Dr. van der Kaaij one day will join a new generation of Cleveland Clinic alumni.) Editor, It was a real privilege as an alumnus of the Department of Thoracic and Cardiovascular Surgery to be invited by Dr. Lars Svensson to this event, preceding an excellent scientific program where a dozen medical experts gave updates on developments in their fields. Everything from ”Surgical Treatment of Ischemic Heart Disease” to “Less Invasive Valve Surgery” was covered. Our visit of six days in Cleveland was as much an eyeopener for my colleague, Dr. Niels van der Kaaij, as it was for me, a confirmation of the previous warm hospitality of Cleveland Clinic since my fellowship many years ago. We saw, in effect, how this world-renowned institution still provides the best- interdisciplinary  care, education and research under the best of governance. We had fabulous tours of the Imaging Institute, the Sydell and Arnold Miller Family Heart & Vascular Institute and of the vast operating theaters, and observed the meticulous surgical procedures of Dr. Svensson  and Dr. Joseph Sabik and their teams. We also had a very instructive private discussion with Dr. Kenneth McCurry about problems of preservation of the donor lung and



visited Dr. Mladen Golubic of the Wellness Institute, who informed us about the pioneering work of Cleveland Clinic in this field. We have sent a separate letter to Dr.Toby Cosgrove with our sincere congratulations for the success of the Institute Model, in which all pertinent experts participate in interdisciplinary patient care, related to specific categories of disease. This model is now in widespread use in European centers. In my opinion, a second motto besides, “To act as a unit’ — although presumably not meant by him as such — was formulated by Dr. Svensson in his address to the laureates and their families on Nov. 13. Dr. Svensson observed that the laureates “went the extra mile,” fittingly describing how they always had given extra effort to the patients, to education, research and governance. This is exactly what I have experienced through the years: Drs. Sones, Favaloro, Cosgrove, Loop, Healy, Smedira, Svensson and other Cleveland Clinic specialists  went thousands of extra miles to deliver keynote  lectures during special symposia in my country, and  they wrote articles for and edited the proceedings, thus spreading the word about the necessity of quality control and expanding the facilities for cardiac surgery in our country, often convincing a hesitant government and reluctant health care insurers. My lasting gratitude to these Cleveland Clinic friends who respond when others ask for help. Jaap Bredée, MD (CATS’75) (Dr. Bredée rose to become head of the department of cardio-thoracic surgery at the University Medical Center in Utrecht, The Netherlands. After obligatory retirement at age 65, he served four years as secretary of the national Medical Specialists Validation Committee, participating in adaptation of this institute to present requirements. Since then, he continues his interest in medical history.)

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contacts Listed among the top 130 women hospital and health system leaders to know by Becker’s Hospital Review is Cleveland Clinic’s Adrienne Boissy, MD (N’96,N/I’98), Chief Experience Officer. She oversees the Office of Patient Experience and its initiatives across the health system. In Adrienne Boissy, MD addition to her current position, Dr. Boissy also is a staff physician at Cleveland Clinic’s Mellen Center for Multiple Sclerosis, with a secondary appointment in the Center for Ethics, Humanities and Spiritual Care. Dr. Boissy has won many awards, including the Sylvia Lawry Fellowship grant from the National Multiple Sclerosis Society and an Arnold P. Gold Foundation grant for humanism in medicine. Leonard H. Calabrese, DO (IM’78, RH’80), of Cleveland Clinic, and Michael M. Lederman, MD, of Case Western Reserve University, longtime collaborators in HIV/AIDS research, received a large vote of confidence from the Richard J. Fasenmyer Foundation: $18.5 million to support their work. The doctors were among the first researchers to study HIV in the early 1980s and have worked together for more than 35 years. The Fasenmyer Foundation, named after the founder of Fairlawn-based RJF International Corp., has given them more than $27 million over the past 24 years to further their work. The Fasenmyer grant will also provide for: • A new training program for fellows

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to study rheumatology, immunology and infectious disease, which began this summer with its first fellow. • The inaugural Richard J. Fasenmyer Professorship in immunopathogenesis at Case Western Reserve University’s School of Medicine, awarded last month to Rafick-Pierre Sékaly • Recruitment and support of junior staff in both fields at the two institutions; • Development of a peer-reviewed publication, Journal of Interesting Immunology and Infectious Diseases. A. Marc Harrison, MD, has been named Cleveland Clinic’s Chief of International Business Development after his accomplished five-year tenure as CEO of Cleveland Clinic Abu Dhabi. In his new role, Dr. Harrison will develop and implement international strategy. This will include identifying new markets for business and esA. Marc Harrison, MD tablishing relationships with international business partners. Dr. Harrison has been a member of the staff for more than 16 years. After joining Cleveland Clinic Children’s in 1999, he served as Medical Director of the PICU from 2001 to 2004; Chair of the Department of Pediatric Critical Care from 2004 to 2006; and Associate Chief of Staff and Director of Medical Operations from 2006 to 2009.

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Tomislav Mihaljevic, MD, succeeds A. Marc Harrison, MD, as CEO of Cleveland Clinic Abu Dhabi. Dr. Mihaljevic will lead the continued expansion of care and service to patients across Cleveland Clinic Abu Dhabi’s five Centers of Excellence and more than 30 medical and surgical specialties. Dr. Mihaljevic joined the Department of Thoracic and Cardiovascular Surgery in 2004. A native of Croatia, he eagerly accepted the chance to serve as Chair of the Heart & Vascular Institute at Cleveland Clinic Abu Dhabi. He is a pioneer of minimally invasive and robotically assisted surgeries and oversaw the launch of Cleveland Clinic Abu Dhabi’s renowned robotics program. As Chief of Staff, he oversaw the recruitment of more than 180 world-renowned physicians and surgeons to Abu Dhabi. Johannes Bonatti, MD, has been promoted to Chief of the Heart & Vascular Institute at Abu Dhabi, leading the daily operations of the institute. Prior to Dr. Bonatti’s Cleveland Clinic staff appointment in 2012, he was professor of surgery at the University of Maryland Medical Center in Baltimore. John Goldblum, MD, Pathology & Laboratory Medicine Institute, received the British Medical Association’s award for best pathology book of 2015 for “Odze and Goldblum Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas, 3rd Edition.” John Goldblum, MD

Robert Coulton Jr., Executive Director of Cleveland Clinic’s Office of Professional Staff Affairs, retired in December after 42 years of service. Mr. Coulton led the office for 27 years, through three CEOs and four Chiefs of Staff. He is succeeded by Michael Michetti, JD, of Cleveland Clinic’s Law Department. Richard O. Lorber, MD (PDCARD’99), is the Cardiology Section Chief at The Children’s Hospital of San Antonio and associate professor in the Department of Pediatric Cardiology at Baylor College of Medicine. Dr. Lorber earned his medical degree and graduated summa cum laude from The Medical College of Wisconsin. He completed his residency at Baystate Medical Center in Springfield, Massachusetts, and his first fellowship in pediatric cardiology at Children’s Memorial Hospital in Chicago. He continued with advanced training in pediatric echocardiography at Mount Sinai School of Medicine and Cleveland Clinic before joining the Children’s Hospital of San Antonio in November 2014. Lori K. Posk, MD, FACP (IM’94), was named Medical Director of Cleveland Clinic’s Twinsburg Family Health & Surgery Center, effective Oct. 1, 2015. She previously served as Associate Medical Director at that location. Dr. Posk was the first woman to receive Cleveland Clinic Alumni Association’s Annual Graduate Level One Award in 1992, six years after the award was created. She also was Chief Resident in Internal Medicine. Dr. Posk practiced internal medicine at the Willoughby Hills Family Health Center before moving her practice to Twinsburg in 2010. She is assistant professor of medicine and has faculty

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appointments at Cleveland Clinic’s Lerner College of Medicine. She also served as the Senior Associate Program Director for the Medicine Residency Program and Lori K. Posk, MD physician advisor for the Lerner College of Medicine. Her specialty interests include geriatrics and preventive medicine. Mark Mayer, MD, Internal Medicine, was elected a Master of the American College of Physicians. Masters are fellows of the college who must be highly accomplished and demonstrate eminence in practice, leadership or medical research. Masters are distinguished by the excellence and significance of their contributions to the field of medicine Mona Gupta, MD (GERM’07, H/ OOPM’08), Hematology and Oncology, was appointed Co-chair of the Research Showcase for the Association of Indian Physicians of Northern Ohio (AIPNO). AIPNO is a nonprofit charitable organization with a membership of more than 300 multispecialty physicians. Members work to foster excellence and professionalism in the practice of medicine and support efforts to improve the availability of healthcare for underserved populations in the community and in India. She also was appointed Co-chair of Palliative Care SIG (Special Interest Group) at AGS (American Geriatric Society). In addition, Dr. Gupta has been accepted into the 2016 FLEX Professional



Elaine Wyllie, MD (CHN’84, EPIL’85), received the Epilepsy Association Legacy Award for Career Achievement at the 24th Annual Epilepsy Gala, which drew a record number of attendees.

Program for Women Faculty at Case Western Reserve University. William Seitz, MD, Orthopaedic Surgery, recently completed his term as the 69th President of the American Society for Surgery of the Hand during the society’s 70th Annual Meeting in Seattle. In his presidential address, Dr. Seitz discussed the society’s evolution, from its beginning with 35 founding members to the current membership of nearly 4,000. At the meeting, Dr. Seitz also chaired a symposium with recognized surgical leaders from around the world. J. Harry Isaacson, MD, and Marvin Natowicz, MD, PhD, were named members of the Case Western Reserve University School of Medicine’s Academy of Scholar Educators. The Academy of Scholar Educators recognizes current faculty members who have made a “sustained and significant contribution to excellence and innovation in medical education.” Each will receive a $5,000 yearly stipend for educational projects during the next three years and become sustaining members of the academy. Edmunds Reineks, MD, PhD (BIOC’10), was appointed Section Head of the new Point-of-Care Testing (POCT) Section within the Laboratory Medicine Department. He will provide leadership and laboratory quality and compliance expertise for both nonwaived and waived POCT programs across the enterprise. He also will serve as Co-chair of the consolidated enterprise Point-of-Care Testing Quality Council, whose goal is to ensure compliance with all applicable federal, state and local laws, agencies and accrediting bodies.

Dr. Wyllie is a professor at Cleveland Clinic’s Lerner College of Medicine and a worldrenowned specialist in epilepsy medicine in Cleveland Clinic’s Epilepsy Center. She is also an editor of the standard textbook in the field, Wyllie’s Treatment of Epilepsy, currently in its 6th edition.

Elaine Wyllie, MD Dylan Wint, MD, Cleveland Clinic Lou Ruvo Center for Brain Health, is the first to hold the Nevada Energy Foundation Chair for Brain Health Education. Endowed chairs recognize physicians’ and Dylan Wint, MD scientists’ contributions to medicine and provide them with long-term funding that allows them to pursue promising research. Dr. Wint specializes in diagnosing and treating neurobehavioral disorders and is committed to training the next generation of physicians and leading medical education programs at the center. Gopal B. Saha, PhD, Emeritus Staff, recently authored the third edition of Basics of PET Imaging, published by Springer. Along with his other publications, Fundamentals of Nuclear Pharmacy, sixth edition, and Physics and Radiobiology of Nuclear Medicine, fourth edition, this text is adopted as a textbook for physicians, residents and

technologists in nuclear medicine. Gary W. Procop, MD, MS, has been elected President of the Trustees of the American Board of Pathology. He also recently was honored by the College of American Pathologists with the Distinguished Patient Care Award for his national work during the Ebola crisis. He also received the Mastership designation by the American Society of Clinical Pathology for his groundbreaking work in test utilization management. Christina Moravec, PhD (R’89), has been named Assistant Dean at Cleveland Clinic Lerner College of Medicine and will lead the school’s basic science curriculum, ensuring that pre-clinical coursework in the first two years successfully Christina Moravec, prepares PhD students for careers as physician-scientists. Continued on page 20

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contacts Education Institute’s 2015 Educator Awards The Education Institute presented 2015 awards to the following faculty: Distinguished Educator Level I Certificate Jane Wey, MD Vinni Makin, MD (END’10) Jeffrey Brown, DO Darlene Lobel, MD Do Gyun Kim, MD Jinesh Patel, MD (CYTOPTH’12) Marina Perez-Fournier, MD Distinguished Educator Level II Certificate Renato Samala, MD (GERM’11, HPC’12) REALL Resident Development Award Rita Pappas, MD This award is presented to faculty who have participated in the Resident Educator and Life-long Learner (REALL) Program and implemented at least three REALL modules for their residency programs. These modules instruct residents on key aspects of being teachers and life-long learners.

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Ashish Khanna, MD (AN’14, CCM’15), received the Society of Critical Care Medicine’s (SCCM) Presidential Citation. This award goes to members who make outstanding contributions of time, energy and resources to the society. Dr. Khanna was also elected to chair the SCCM’s In-Training Section, starting with the 2016 World Congress in February. Marsha Kay, MD (PD’90, PDGE’93), Chair, Department of Pediatric Gastroenterology, and Robert Wyllie, MD, published the fifth edition of their textbook, Pediatric Gastrointestinal and Liver Disease. The first edition was published in 1993, and the book is one of the leading references in the field. Carol Burke, MD (GE’93), is the new Vice Chair of the Department of Gastroenterology and Hepatology in the Digestive Disease Institute. Her responsibilities include staff development and research oversight. Rebecca Flyckt, MD (REI’19) (Obstetrics and Gynecology), is a featured member of Cleveland Clinic’s Uterine Transplant Trial team, spearheaded by Andreas Tzakis, MD, PhD, and Tommasso Falcone, MD. The complexity of the clinical trial requires a team of specialists different from that of a typical organ transplant and includes many members. Leonard H. Calabrese, DO (IM’78, RH’80), Rheumatologic & Immunologic Disease, received the American College of Rheumatology’s Master Designation. This is one of the highest honors the college bestows to recognize outstanding contributions to the field of rheumatology through scholarly achievement or service to patients, students and the profession.

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Tolga Erim, DO (IM’05), has been appointed Director of Endoscopy at Cleveland Clinic Florida. Dr. Erim has been a member of the Weston staff since 2011.

served the society selflessly and with distinction throughout their professional careers.

David Streem, MD (P’99), was named Section Head of Alcohol and Drug Rehabilitation at Lutheran Hospital. Judy Jin, MD (ED’12), a member of the Brenda Lewis, DO, and Basem Abdelmalak, MD Endocrine Surgery, Endocrinology & Basem Abdelmalak, MD Metabolism Institute, received the (AN’00, CCM’01), Ohio Society of Bruce Hubbard Stewart Award for Anesthesiologists’ outgoing 2015 Humanistic Medicine, while Ruth President, hands the post to Dr. Paul Imrie, MD, Community Pediatrics, Wojciechowski, of the University received the Sam and Maria Miller of Cincinnati at the society’s 2015 “Master Educator” Award. annual meeting. Mindy Estes, MD (ACLPTH’84), Charles Modlin, MD (U/RT’96) was who serves as President and CEO of named the 2015 Black Professional St Luke’s Health System in Kansas of the year at the Black Professionals City, recently was appointed to the Association Charitable Foundation American Hospital Association Board dinner in November. CEO and of Trustees. President Toby Cosgrove, MD, who chaired the event, commended Dr. Jianguo Cheng, MD, PhD, Modlin for his tireless efforts to end Anesthesiology Institute, was re-elected healthcare disparities in minority and Vice President for Scientific Affairs underserved populations. of the American Academy of Pain Medicine (AAPM). His research on stem cells and pain management, supported by the Department of Defense, will be In Memoriam featured in the plenary highlight session Donald J. Coburn, MD at AAPM’s 2016 annual meeting in (TCS’52), has died at age Palm Spring, California. 93. Dr. Coburn practiced Brenda Lewis, DO (AN’84, CTA’85), medicine for 35 years at received the Ohio Society of the Euclid Clinic and Euclid Anesthesiologists 2015 Distinguished General Hospital, retiring Service Award at its annual meeting. in 1986. Survivors include Donald J. This is the highest honor the society his children James D. (wife Coburn, MD awards to recognize members who Continued on page 21 clevelandclinic.org/alumni

Margaret “Marty” Grey); Catherine C. “Sissy” Costello (husband Daniel W.) of Columbus; Howard E. (wife Anne); Patrick L.; Christopher M. (wife Nancy L.); and Mary Rose Sullivan (husband Mark J.) of Columbus, his daughter-in-law, Peggy Spaeth; and his 16 grandchildren and seven greatgrandchildren. Bertram “Bert” Fleshler, MD, died in his adopted hometown of San Diego, California, in October 2015. He will be remembered as a man of voracious intelligence, wideranging interests and professional Bertram accomplishment, as Fleshler, MD well as a husband, father, brother, uncle and grandfather. He was born in Brooklyn, New York on May 1, 1928, and grew up in Jersey City, New Jersey, the son of Jewish immigrants from Czarist Russia. His was raised to value education and learning - activities that he pursued throughout his life. He graduated from high school at 16, college (the University of Wisconsin) at 19, and medical school (Boston University) at 23. He served in the U.S. Air Force in Oslo, Norway, where he met his wife, Jean Birrell, who grew up in England. After returning to the U.S., he married Jean, completed his medical training and, in 1958, moved to Cleveland. Dr. Fleshler worked at Cleveland Metropolitan General Hospital, St. Vincent Charity Hospital, and Cleveland Clinic. He also was a professor of medicine at Case Western Reserve University. Bertram wrote numerous scholarly articles and textbooks, including the textbook



Clinical Gastroenterology, co-edited with Drs. Edgar Achkar (GE’69) and Richard Farmer, which has been used by countless generations of practitioners and students. He was a trusted mentor and advisor to generations of medical students and young physicians. Geraldine “Gerri” S. Hall, PhD, 68, formerly of Cleveland, died January 8 following a lengthy illness. She was born in Elizabeth, N.J. in 1947, the daughter of the late Joseph and Victoria (Tower) Karausky. Dr. Hall was a 1969 graduate of St. Francis College in Lorretto, Pa., rceiving a Bachelors in Science with emphasis on Biology in a Pre-Med Program. She received a PhD in Microbiology from St. Bonaventure in 1975, and additional training in Microbiology at Cleveland Clinic from 1977-1979. Geraldine S. Dr. Hall worked Hall, PhD as a clinical microbiologist at Cleveland Clinic for 37 years. She also was a Professor of Microbiology at Lerner College of Medicine. Dr. Hall was a member of the Northeast Ohio Association of Clinical Microbiology (TIIMS), Southeast Association for Clinical Microbiology (SCACM), American Society for Microbiology (ASM) and the American Society for Clinical Pathology (ASCP). Survivors include her husband, Dr. James O. Hall, and a son, James Joseph “JJ” (Gabriela Prieto) Hall, of Toledo, Ohio. Mark Eric Lauer, PhD (RES/ BE’09), age 42, of Cleveland Clinic’s

Department of Biomedical Engineering (BME) in the Lerner Research Mark Eric Lauer, Institute, was PhD killed in a car accident in October 2015. Born in Ft. Thomas, Kentucky, May 9, 1973, he earned his Bachelor of Arts in chemistry at Northern Kentucky University and his PhD in cell biology and anatomy at Louisiana State University Health Sciences Center. Dr. Lauer began his career at Cleveland Clinic in 2001 as a research fellow. He moved from research associate to project staff to staff scientist in five years, and in June he was promoted to assistant staff. Dr. Lauer was Principal Investigator of an R01 (investigator-initiated) grant from the National Institutes of Health on TSG-6, a factor involved in inflammation of the airways. He focused on lung disease, especially cystic fibrosis, and was working toward a potential breakthrough technology – “nebulized hyaluronan,” delivered by an inhaler – that would help young patients with cystic fibrosis breathe more normally. Michael G. McKee, PhD, a member of Cleveland Clinic’s staff for 46 years and an excellent clinician and role model, passed away in October 2015 at age 84. Dr. McKee earned his doctorate in clinical psychology from the University of California at Berkeley, where he also taught for several years before joining Cleveland Clinic’s staff in July 1969. He served as Vice Chairman of the Department of Psychiatry and Psychology for many years and also chaired the

Section of Health Psychology and General Psychology, directing a program that focused on diagnosis and treatment of stress-related disorders and enhancement of health and performance through improved self-regulation. He was internationally recognized for his expertise in biofeedback and served as a consultant in the Michael G. fields of business, McKee, PhD healthcare, education and athletics. A Past-President of the Association for Applied Psychophysiology and Biofeedback, Dr. McKee received the association’s Presidential Service Award. He was President of the Cleveland Academy of Consulting Psychologists for three terms and the Cleveland Psychological Association for two. He also served as President of the Ohio Psychological Association and received its Distinguished Service Award. He was Chairman of ISMA-USA, the U.S. branch of the International Stress Management Association, and was selected for the National Academies of Practice - Distinguished Practitioner in Psychology, which is limited to 150 members. He served on the faculty of four universities, lectured widely throughout the country and abroad, and made hundreds of appearances on local and national radio and television, including The Today Show. Dr. McKee is survived by his wife of nearly 60 years, Theodora M. “Teddy” (nee Thorson) McKee, and four children, Cory L. (John) Polena, Pittsburgh, Carol K. (Steven) BaickerContinued on page 22

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contacts McKee, of Pittsburgh, Anna M. (Doug) Grossman-McKee, Shaker Heights, Ohio, and Evan M. (Katey Viekorn) McKee, Columbus, Ohio, along with 13 grandchildren and one greatgrandchild, with two more on the way. Steven I. Reger, PhD, age 76, an alumnus and former associate professor at the University of Virginia, was a biomedical engineer. He was a Freedom Fighter in the Steven I. Reger, 1956 Hungarian PhD Revolution before emigrating to the United States, where he became a naturalized citizen. Dr. Reger was the Emeritus Director for Rehabilitation Technology in the Department of Rehabilitation Medicine at Cleveland Clinic and a founding member of National Pressure Ulcer Advisory Panel. Dr. Reger was wellknown nationally and internationally for his academic excellence and research in rehabilitation engineering and wound care. He was awarded numerous patents and research grants, and he authored more than 200 scientific publications. Dr. Reger also provided clinical services to patients with various mobility issues for more than 30 years. He is survived by his beloved wife, Sally E. Reger; children, Steven A. Reger (Stephanie) and Kirsten R. Richards (Harry K.) and three grandchildren. Vivek H. Singh, MD, MPH (P’02), died at age 47. He was Chairman of the Department of Psychiatry at Texas Tech University. Dr. Singh began his role in El Paso, building strong community relations, and hired six new faculty

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Giving Giving to medical education at Cleveland Clinic in memory of a fellow alum is a meaningful way to express sympathy. Please be assured that your gift will help preserve the highest standards of education and training of future generations of physicians and scientists. For more information, please call Mindy Stroh, Director of Alumni Relations, at 216.444.2487.

physicians. In less than five months, Dr. Singh built the foundation for a world-class psychiatry department that will continue to work with the El Paso Vivek H. Singh, community to MD, MPH identify and address the mental health needs of the population, provide leading-edge care to those with mental illness in El Paso, and integrate mental health into primary care settings. Dr. Singh came to TTU El Paso from the University of Texas Health Science Center at San Antonio, where he was a professor of Psychiatry and Interim Vice Chair for Clinical Affairs, Medical Director of University Hospital Psychiatric Services, Director of the Psychiatric Consultation Liaison Service, and Chairman of the Institutional Review Board. Dr. Singh was born in Pandepur, India, on March 7, 1968 and went on to earn his medical degree at Gandhi Medical College in Hyderabad, India, in 1994, and his master of public health degree from the School of Public Health at the University of Illinois. Following his residency at Cleveland Clinic, he obtained post-doctoral fellowship training in

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psychopharmacology and biological psychiatry. He was board-certified in Psychiatry and Psychosomatic Medicine by the American Board of Psychiatry and Neurology. His clinical, research, and teaching activities were focused on bipolar disorders and psychosomatic medicine, and he authored numerous articles and book chapters on bipolar disorders. He also was an active reviewer for several psychiatric journals and member of editorial boards. Dr. Singh was a highly sought-after national speaker on bipolar disorders and educated practicing psychiatrists in the assessment, diagnosis and treatment of this illness.

research with deep brain implant electrodes and surgery for Parkinson’s disease. Dr. Todd is the inventor of the Todd-Wells Stereotactic Frame. He is survived by four sons, their wives, five grandchildren, and his brother Arthur.

Edwin Todd, PhD (NS’57), died in Pasadena, California, from congestive heart disease. He entered medicine after serving as a tech sergeant in the U.S. Army Medical Corps in World War II. After the war, he met and married his wife, Lannie. Along with his medical degree, he earned a master’s in liberal arts (USC), a law degree (Loyola), Edwin Todd, PhD and a doctorate in renaissance history and art (UCLA). His neurosurgical career includes

in a tight-knit clan of cousins, aunts and uncles, grandparents and friends. He surfed, ran track, and his dad taught him to work on cars, which led to a lifelong love affair with automobiles –the faster, the better. He was introduced to medicine at his first job as an orderly at the newly opened Little Company of Mary Hospital in Torrance, California, while he went to school. He earned his PhD at the University of California (1970). He attended medical school at the University of Health Sciences in Medicine (DO) in Iowa and completed

Bud Edward Quintana, PhD (TCS’78), died in November 2015 at Ohio State University Medical Center, the result of an accident while hiking. He was 73. Dr. Quintana was born in Hawthorne, California, the oldest of three sons. He led a colorful and accomplished Bud Edward life. He grew up in Quintana, PhD southern California

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clevelandclinic.org/alumni

his training in general and thoracic surgery at Cleveland Clinic in 1975. Much of Dr. Quintana’s career was in trauma and emergency care medicine, and he also taught medical students and residents at several universities. He worked and played hard, cruising the highways of America on motorcycles and in race cars, which he also collected. He loved music and even supported himself while in medical school by playing piano. He most recently worked as Director of the Suboxone program, laser treatment and outpatient surgery at Community Health Center, and was on the faculty at NEOMED in Summa Health System’s residency program for family physicians. He was awarded Teacher of the Year in 2008. Albert Dale Gulledge, MD (P’92), was born in Lubbock, Texas, in 1932 to Albert and Hazel Gulledge. He grew up moving frequently around the Midwest because his father was a store manager “troubleshooter.” In some ways, he followed his father, except that he focused on people with troubled lives. His interest in becoming a doctor stemmed from serving as a medical corpsman in the U.S. Air Force. While working on a bachelor of science degree at the University of Kansas, he played on the baseball team, until his shoulder was injured. A rain delay on a Houston trip for baseball gave him a chance to visit Baylor University College of Medicine, where he decided to attend. He earned a master’s of science and his medical Albert Dale degree there, Gulledge, MD

graduating with honors. After an internship at the University of Minnesota, he became a fellow in internal medicine at the Mayo Graduate School, thinking he would become a cardiologist. However, he instead became interested in the effect of illness on the mind and spirit, and switched to psychiatry. He became the first psychiatrist at the Wichita Clinic and also began teaching family practice residents about taking care of their patients’ emotional needs. From then on, he was a teacher. He was invited to join the staff of the Mayo Clinic, where he worked with cardiologists to establish their first cardiac rehabilitation program. In 1974, the University of South Dakota School of Medicine was expanding to a four-year school with a focus on family medicine, and after the dean heard Dr. Gulledge teaching family practice residents in Wichita, he recruited him to become the first Chairman of the Department of Psychiatry. Next, he was recruited by Cleveland Clinic to develop a new consultation service that would help people with chronic, critical and terminal illnesses. One section of the Liaison Psychiatry Service still bears his name. He also was the first Chair of the ethics committee. He was President of the Academy of Psychosomatic Medicine and a Board Examiner for the American Board of Psychiatry and Neurology. He was elected to the American College of Psychiatry, and he wrote and edited books, wrote and co-wrote many articles, and was a popular and frequent speaker. When Cleveland Clinic opened in Ft. Lauderdale, Florida, he became Chair of the Department of Psychiatry there. Because of his interest in

educating family doctors, he was elected to serve on The American Board of Family Medicine Board of Directors. After “semi-retirement,” he moved to Boise, Idaho, and joined his friend, Terry Gipson, MD, in private practice. He then became Director of Outpatient Psychiatry at St. Alphonsus Medical Center and continued to teach family practice residents in the Idaho program. In 1998, he fully retired. Dale is survived by his wife of 58 years, Patricia Gulledge, and sons, David Dale(Anne) and Robert Brett Gulledge, (Dr. Anita Doshi). George Arack, MD (IM’50), died in October 2015 at age 99. He was a physician in Santa Rosa, California, from 1950 to 1977. Dr. Arack was well-respected and known by many residents in the Santa Rosa area. After retiring, he and his wife, Phyllis, George Arack, managed MD antiques for 30 years. When Phyllis passed away, he and Bobbie Sparrow were married and were together for nearly 10 years. He is survived by four children: George Jr., Jim, Elizabeth (Betsy) and John, all of California.

Please Keep in Contact Clinic colleagues are interested in hearing your news. Please drop us a line at ClevelandClinic.org/Alumni or e-mail [email protected].

Consider nominating someone for an Alumni Award Today! Each year, the Alumni Board of Directors honors its own with special award presentations to acknowledge their achievements. All award winners receive a plaque in their honor and are recognized by engraving their names on a permanent plaque which is on display in the Alumni Office. All award winners will also be invited and honored at our Fall Board Reception. The award categories include Distinguished Alumnus Award, Special Achievement Award and Service Award. Visit our website to nominate an alum today: http://alumni. clevelandclinic.org/. June 1, 2016 is the deadline to nominate.

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Volume XXVI, No. 1 | Winter 2016 Alumni Connection is a publication of the Cleveland Clinic Alumni Association, produced in conjunction with Development Communications, for medical alumni and friends by the Philanthropy Institute, Cleveland Clinic, 9500 Euclid Ave./DV1 (White Mansion), Cleveland, OH 44195. 216.444.2487 | 800.444.3664 (24/7 voice mail) | fax 216.445.2730 e-mail [email protected] | website: clevelandclinic.org/alumni Cleveland Clinic, founded in 1921, integrates clinical and hospital care with research and education in a private, nonprofit group practice. Cleveland Clinic depends on the generosity of individuals, families, corporations and foundations to ensure its continued excellence in patient care, medical research and education. Cleveland Clinic realizes that individuals would like to learn more about its particular programs, services or developments. At the same time, we fully respect their privacy. If you do not wish to receive any materials containing this information, please contact us.

CCF Alumni Association Board of Directors Mauricio A. Perilla, MD Jonathan D. Emery, MD Dale R. Shepard, MD, PhD Jeffrey M. Goshe, MD Brian P. Griffin, MD Alan W. Davis MD Mark K. Grove, MD Toribio C. Flores, MD Sara Pecorak Lappe, MD Jonathan L. Myles, MD Alexis L. Grucela, MD Elumalai Appachi, MD Divya Singh-Behl, MD Ralph M. Rosato, MD Mario Skugor, MD Leo J. Pozuelo, MD Michael R. Puff, MD Octavian Ioachimescu, MD, PhD Lee M. Adler, DO Richard C. Page, PhD Pauline Kwok, MD Rochelle Rosian, MD Albrecht H. Kramer MD Thomas J. Maatman, DO James W. Lewis, MD Leonard P. Krajewski, MD Guy M. Sava, MD Joddi M. Neff-Massullo, MD Steven Benedict, MD Susan J. Rehm, MD  President Conrad H. Simpfendorfer, MD   Vice President Dale R. Shepard, MD, PhD   Secretary Treasurer Gary H. Dworkin, MD  Immediate Past President

Ex-Officio Members Elias I. Traboulsi, MD Kathleen N. Franco, MD Daniel Joyce, MD Melinda Stroh Emeritus Members Robert E. Hobbs, MD William L. Proudfit, MD William M. Michener, MD

Melinda Stroh Director Tara Fenner  Assistant Director Jim Marino Editor, Alumni Connection