Think it. Make it. Ship it.

BIOSCIENCE INDUSTRY A hub for private sector innovation supported by institutional research and development—the Greater Portland bioscience industry is poised for unprecedented growth.

WORKFORCE TALENT FOUNDATION FOR INNOVATION LOW COST FOR BUSINESS

OREGON’S LIFE SCIENCE AND BIOTECHNOLOGY INDUSTRY

The region has a demonstrated strength in the bioscience

The Greater Portland region is widely recognized for its

of 30 percent in ten years from 2001 to 2011, outpaces

computer and electronics industry that helps drive our

Texas, Massachusetts and California (the US economy

medical device sector. Bolstering this strength within the

retracted by 2.9 percent in the same time frame).

industry with more than 13,556 people employed at 802 establishments. In addition, our employment growth rate

bioscience industry is our comprehensive and resolute commitment to R&D in the biotherapeutics sector.

WASHINGTON

Combine these assets with regional qualities that attract

COLUMBIA RIVER

educated talent and foster a collaborative spirit and you have a region poised for true innovation.

SKAMANIA COLUMBIA PACIFIC OCEAN

OREGON BIOSCIENCE EMPLOYMENT GROWTH: 2001-2011

OR: 30.6%

2

1

CLARK

3 WASHINGTON

MULTNOMAH

YAMHILL CLACKAMAS

TX: 18.5% MA: 15.1% CA: 13.0% US: 6.4% 2001

2011 US Emp: -2.9%

Source: BIO/Battelle State Bioscience Industry Development 2012 Report

OREGON LEGEND 1

PORT OF VANCOUVER

I-5

2

PORT OF PORTLAND

I-205

3

PDX INTERNATIONAL AIRPORT

I-84

BNSF RAILROAD UNION PACIFIC RAILROAD

Bioscience Industry 1

Uniquely positioned within the Pacific Northwest, the Greater Portland region encompasses two states, seven counties and 25 municipalities. What that means for your business is simple: options. Already home to globally competitive companies like Intel, FEI, and Biotronik – and with a gross regional product of $124 billion - Greater Portland offers a variety of sites, cultures and assets to meet your business needs.

TALENT ATTRACTION In looking to expand a company, the ability to attract talent is critical. Greater Portland is a magnet for young, diverse, well-educated workers. In 2014, more than 4,200 net new residents over the age of 25 with a bachelor’s degree or higher moved to the region, one of the highest mobility rates in the nation. DOMESTIC NET MIGRATION WITH A BACHELOR’S OR HIGHER: POPULATION 25 YEARS AND OLDER

WORKFORCE TALENT Portland regional employment is highly concentrated in

4,769

4,536

STEM fields (science, technology, engineering and math),

3,412

accounting for 7.2% of metropolitan regional jobs versus

1,048

5.8% nationwide. This aligns with the industry, and will

873

continue to develop along with the growing bioscience opportunities. In addition, within the bioscience industry

AUSTIN

PORTLAND

SEATTLE

PHOENIX

S.L.C.

616 DALLAS

DENVER

specifically, the region offers the necessary expertise -990

at competitive wages, along with the bio workforce development and training partnerships to help companies scale up for growth.

Source: US Census Bureau, 2013 American Community Survey 1-Year Estimates

RELEVANT INDUSTRY TRAINING

BIOSCIENCE EMPLOYMENT AND WAGES FROM COMPARATIVE US METROS

In cooperation with Business Oregon, the Oregon Average Annual Wage

Total Employment

Bioscience Association has created a unique,

70,000

customized program to help develop the next

60,000

generation of highly skilled technical and managerial

30,000

employers in Oregon, the program recruits

20,000

cohorts of students to receive its medical device

10,000

professional development certificates in Medical

0

Device Foundations and Quality Assurance. This

lt L

o ie g D n

Sa

Sa

ak e

le ig h Ra

tla Po r

D

Ci ty

in cooperation with some of the largest bioscience

nd

talent for the state’s bioscience industry. Designed

en ve r

50,000 40,000

pioneering workforce training approach educates mid-level professionals who have the education and professional background but not bio-industry-specific training such as FDA and regulatory compliance, Lean

Source: Bureau of Labor Statistics, May 2013

Manufacturing, quality control, design controls, ISO 9001 and risk management.

WITH CLOSE TO 3,300 EMPLOYEES, GREATER NATION FOR EMPLOYMENT LEVELS WITHIN THE

OREGON HEALTH & SCIENCE UNIVERSITY (OHSU)

MEDICAL DEVICE SECTOR.

•

1,000 research projects ongoing

•

1,100 scientists, healthcare professionals and staff

•

$1.5 billion in R&D funding

PORTLAND IS ONE OF THE TOP 25 REGIONS IN THE

– BATTELLE ANALYSIS OF BLS QCEW DATA, 2014

Bioscience Industry 2

FOUNDATION FOR INNOVATION The historic $1 billion Knight Cancer Challenge, a

companies that are growing this emerging industry in the

national fund-raising campaign spearheaded by Nike

region. As the largest philanthropic effort of its kind, this

co-founder, Phil Knight, to raise funds to cure cancer, will

ambitious fund-raising initiative has generated international

drive innovation and investment for several bioscience

attention for OHSU’s Knight Cancer Institute.

Agricultural Bio-agriculture Neutroceuticals

Diana Plant Sciences

Medical foods

Medolac

Biofuels Fuel using biomass to make cellulosic ethanol

Z-Chem

Drugs and Pharmaceuticals Research

Oregon Translational R&D Institute (OTRADI)

Manufacturing/Packaging

Genentech

Incubator

OTRADI’s OBI (OTRADI’s Bioscience Incubator)

Basic research

Aronara UbiVac

Drug development

Paragon Bioteck Inc. 13 Therapeutics Galena Biopharma

Medical Devices Implantables (pacemakers, orthopedic surgical products)

Biotronik Acumed

Patient monitors

Welch Allyn

Biosensors

TE Connectivity

Equipment

ShellLabs

Wound care

RevMedx SAM Medical

Research and Testing Components

Precision Wire Components

Diagnostics

MolecularMD Sedia Bio

Labs - Wet Labs

Knight Cardiovascular Institute/OHSU Knight Cancer Institute/OHSU Portland State Business Accelerator OTRADI’s OBI

Animal research

OHSU Primate Center Yecuris

Production/Biomanufacturing

AbSci

Data/Analytics

Tier 7 Consulting

Bioscience Industry 3

BIOSCIENCE COLLABORATORS

Portland State University Business Accelerator

Several key institutes now support the foundation for

The PSU Business Accelerator is home to more than 30

innovation, including the following bioscience collaborators:

startup companies in technology, bioscience and clean

Oregon Health & Science University (OHSU), Oregon State University (OSU), and Portland State University (PSU) at the Collaborative Life Sciences Building (CLSB) In close collaboration with OHSU/OSU/PSU, the Collaborative Life Sciences Building in Portland’s South Waterfront combines world-class labs, classrooms, lecture halls, offices and specialized research and simulation rooms. Researchers from various institutions come together to solve the bioscience challenges of today, and tomorrow. This 500,000-square-foot facility lays the foundation for development of Oregon’s future scientists through OSU, OHSU, and PSU academic programs and serves as the catalyst for collaboration. This facility will be facility will be located next to the future Knight Institute, where more than 500 research scientists and healthcare professionals will focus on research, advanced diagnostic testing, ground breaking biorepositories and clinical expertise.

Oregon Translational Research and Development Institute (OTRADI) and OTRADI Bioscience Incubator (OBI)

tech, including companies founded by PSU and OHSU faculty and students. Approximately one-third of Business Accelerator companies are in the life sciences. The PSU Business Accelerator offers turnkey space and services to promising high-growth companies. Resident companies gain access to mentors, connections and a range of structured and informal sessions such as CEO Council, pitch-fests, brown bag topics and social networking. They also gain access to PSU student teams and interns working on business or engineering projects, who serve as a talent pipeline in a competitive hiring market. The Accelerator is located between PSU and OHSU and is a short walk from the new Collaborative Life Sciences Building.

LOW COST OF BUSINESS Greater Portland is considered a regional bargain. If you desire a West Coast location, the Portland region is a wonderful, reasonably priced gateway to some of the most significant global cities in the world.

COST OF LIVING

OTRADI, a nonprofit bioresearch institute co-funded by

In minutes

Median Home Value

Greater Portland

25

$249,300

$21.59

$0.38

$56,978

San Francisco

30

$557,700

$56.62

$1.62

$74,992

Seattle

29

$293,700

$29.97

$0.54

$65,667

Los Angeles

29

$428,500

$30.96

$0.61

$57,271

Price per square foot

Price per sq. ft./month

Average Commute

the State of Oregon, works with universities in the state to rapidly develop and commercialize new products and spur startup company formation and growth. In June 2013, OTRADI built out and opened the state’s first and only bioscience-focused incubator. The OTRADI Bioscience Incubator (OBI) provides bio startup companies with shared scientific equipment, wet lab space, collaboration areas, specialized lab facilities and the focused mentoring and expertise needed to take research from the lab to the market. Due to high demand, the OBI recently expanded from 13,000 square feet housing six bio-startups to 17,000 square feet housing ten bio-startups. This resounding success and ever-growing demand signals that the Greater Portland region is poised for bioscience innovation.

In minutes

Class A Office

Industrial

Price/sq ft

Price/sq ft /month

Median Household Income

The cost of living for Greater Portland residents - lower than Los Angeles, San Francisco, or Seattle - is a well kept secret. Similarly, average salaries in the Greater Portland region tend to be lower than in other West Coast metros. The continued growth in our region’s talented workforce suggests that skilled workers understand that their wages go further here. The low cost of doing business is also a highly valued benefit to employers.

Three of the 10 companies in OBI are from outside the Portland region, and at least two of the 10 companies are ready to move beyond the OBI Incubator into a larger and more permanent location.

Bioscience Industry 4

Reykjavik

Amsterdam

Vancouver BC

Frankfurt

PDX Tokyo

Chicago

San Francisco

New York

Washington D.C.

LA Direct to Asian markets via flights and shipping lanes

Guadalajara

MODERATE TAXES The Greater Portland region includes two states — Oregon

Air service is easily accessible, with the Portland

and Washington. This means businesses here have the

International Airport (PDX) less than nine miles from

advantage of considering two distinct tax codes to

downtown Portland, linked directly to the city via light

determine which state is the best fit. Whichever they end

rail. There are 249 non-stop daily departures, including

up choosing, businesses will find that both states have

direct flights to New York; San Francisco; Vancouver,

designed their tax codes to attract and retain companies.

BC; and Washington, DC. Daily international flights

As indicated below, both Oregon and Washington rank

run to Tokyo and Amsterdam. More than 15.9 million

in the top quarter of the nation for business-friendly tax

passengers passed through PDX’s gates in 2014. Global

structure.

access through a frequently visited airport allows you to save time and money with direct flights at lower costs.

2015 STATE BUSINESS TAX CLIMATE

WA #11 OR #12

MT #6

ND #25

ID #19 WY #1

NV #3

CA #48

UT #9

AZ #23

VT #46 MN #47

SD #2

IA #41

NE #29 CO #20

IL #31

KS #22 OK #32

NM #38 TX #10

AK #4

WI #43

HI #30 15 Best Business Tax Climates

MO #17

OH #44 KY #26

PA #34

WV #21

VA #27 NC #16

TN #15 AR #39

MS #18

AL #28

ME #33

NY #49

MI #13

IN #8

VOICES FROM THE INDUSTRY

NH #7

GA #36

SC #37

LA #35 FL #5

MA #24 RI #45 CT #42 NJ #50 DE #14 MD #40 DC (#45)

15 Worst Business Tax Climates

Source: State Business Tax Climate Index, Published October 28, 2014

GLOBAL ACCESS Well positioned at a crossroads of ocean-bound and river shipping lanes, interstate highways, and national rail lines, including Union Pacific and Burlington Northern Santa Fe, Greater Portland is a global hub for export opportunities.

Bioscience firms are growing in greater Portland for several reasons, as shown the company profiles below.

BACKGROUND: Founded

in 1976. Launched operations in

Oregon in 2010. EMPLOYEES IN OREGON: 400 LARRY SANDERS, VP AND GM, HILLSBORO TECHNICAL OPERATIONS: On a skilled workforce: ”Our continued investment in the area represents the commitment we have to the Hillsboro community and Oregon, which has provided a highly skilled workforce and great business environment for our company’s growth.”

With five cargo carriers serving the Asia market, the Port of Portland offers easy and direct access to overseas shipping and receiving services. Bioscience Industry 5

BACKGROUND: Founded EMPLOYEES: 2,202

in 1917

in Oregon (approximately 5,000

nationwide) SUBSIDIARIES/DIVISIONS: 6

Regional Health plan; several innovative health startups including HealthSparq, Lifemap, OmedaRx, SpendWell, Wellero, and Direct Health Solutions with divisions Enigma Health and hubbub.

BACKGROUND: BIOTRONIK

was founded in 1962 and MSEI was founded in 1979. The Oregon campus was opened in 1979.

EMPLOYEES IN OREGON: 428 JUERGEN LINDNER, GENERAL MANAGER:

people in our community live healthier lives is what we’re about, aligning well with the lifestyle and ethos of Portland and Oregon. We’ve brought on talent from many different industries, including a chief marketing officer from ESPN and a chief data officer from IBM. These are just two examples of people attracted to us because of our innovation, our cause and our base in the Portland community. The well-matched ideals of our company and this city continue to bring us smart, forward thinking individuals passionate about transforming the health care system.”

On Greater Portland as an Emerging Bioscience Hub: “Still today, Micro Systems Engineering is the primary location for one of the leading companies for implantable medical electronics and continues to leverage the technology and talent infrastructure of Oregon, including its proximity to other key technology hubs on the West Coast. The organization has grown to several hundred employees with over 80% in R&D, design, engineering, and technology. The highly efficient and automated manufacturing operation is not only able to support the rapid growth of BIOTRONIK but also supports other companies in the medical device industry by offering design and manufacturing services.”

On Startups: ”We

On the Local Workforce:

MARK GANZ, PRESIDENT AND CEO: On Talent: ”Helping

are driven to transform health care to be more person-focused and economically sustainable. With this lens we’ve incubated and invested in numerous consumer-focused Portland-based startups such as HealthSparq, Wellero and CoPatient. We believe the future of health care relies on progressive, innovative ideas that will change the way people experience health care, and these companies are helping us foster those ideas and lead the charge towards a health care transformation business climate with support from trade organizations, such as the Oregon Bioscience Association; the innovation mindset in the region; and readily available access of other senior leaders who proactively are willing to help.”

On Why Portland is a Great Place for Health Care Innovation: ”Our forefathers started the country’s first health plan almost 100 years ago in Pacific Northwest logging camps where workers came together to pool their funds in case of injury or illness. This innovative idea, and many ground breaking companies, illustrate the pioneering spirit of the region and attract entrepreneurs to launch and build new companies. The pioneering spirit is inspiring a level of innovation in the health care industry as well, advancing the transformation toward a sustainable, consumer focused healthcare economy.”

Matt Miller, VP of Business Development [email protected] 503.445.8065 x109 www.greaterportlandinc.com

“Oregon continues to be an attractive location for talent not only for the entire US, but also for transfers from international locations, which is critical to enhance the collaboration in a global organization. Oregon’s strength in collaboration with other biotech companies, colleges, and universities has created a great network for research, development, and ongoing training. We feel that the Greater Portland area is on track to successfully compete with other leading Biotech centers of excellence such as those in Switzerland or Germany.”

JOIN US In Greater Portland, innovation is driving business. With a lifestyle that draws a young, talented, creative and well-educated workforce, businesses are seizing on this opportunity and relocating or expanding here in record numbers. Be one of them. Don’t miss the chance to become part of a region that is pioneering new approaches to industry. Join us. Dennis McNannay, Executive Director [email protected] 503.548.4432 www.oregonbio.org