CURRICULUM VITAE

A. BUTIR-BUTIR PERIBADI (Personal Details) Nama Penuh (Full Name) YEAP SWEE KEONG No. MyKad / No. Pasport Warganegara Bangsa (Mykad No. / Passport (Citizenship) (Race) No.) Malaysia Cina Jawatan (Designation) Felo Penyelidik Tarikh Lahir (Date of Birth) Alamat Semasa (Current Address) Institute BioScience Universiti Putra Malaysia 43400 Serdang, Selangor

Jabatan/Fakulti (Department/Faculty) Institute BioScience Universiti Putra Malaysia 43400 Serdang, Selangor

Gelaran (Title):Dr Jantina (Gender) Lelaki 2 Okt 1982

E-mel dan URL (E-mail Address and URL) E-mail: [email protected]

H/P:012-4684981 B. KELAYAKAN AKADEMIK (Academic Qualification) Nama Sijil / Kelayakan Nama Sekolah Institusi Tahun (Certificate / (Name of School / (Year Qualification obtained) Institution) obtained) Bachelor Science Universiti Putra 2007 (Biotechnology) Malaysia Ph. D Universiti Putra 2010 Malaysia C. KEMAHIRAN BAHASA (Language Proficiency) Bahasa / Language Lemah Sederhana Baik Poor (1) Moderate Good (3) (2) English Bahasa Melayu Chinese

Bidang pengkhusususan (Area of Specialization) Biotechnology Animal Cell Biotechnology

Amat Baik Very good (4) 4

Cemerlang Excellent (5)

4 5

D. PENGALAMAN SAINTIFIK DAN PENGKHUSUSAN 1/4

(Scientific experience and Specialisation) Organization Position

Start Date

End Date

Expertise

Tiada

E. PEKERJAAN (Employment) Majikan / Jawatan / Jabatan / Department Employer Designation

Universiti Putra Malaysia

Tarikh lantikan / Start Date

Research Assistant

Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia Postdoctoral Institute of BioScience, Universiti Researcher Putra Malaysia Research Institute of BioScience, Universiti Fellow Putra Malaysia

2007

Tarikh tamat / Date Ended 2010

2010

2012

2012

To date

F. ANUGERAH DAN HADIAH (Honours and Awards) Name of Title Award Award Type awards Authority Academic Refer to the Awards attachment Non-Academic Awards Awards of Merit

-

-

-

Year

-

-

G. SENARAI PENERBITAN (Sila masukan nama pengarang, tajuk, nama jurnal, 2/4

jilid, muka surat dan tahun diterbitkan) (List of publications – author (s), title, journal, volume, page and year published) Journal Refer to the attachment 1 Books/Monographs Chapter in book

Refer to the attachment 1

Proceedings

Other publications

Omar, A.R., Rasoli, M., Moeini, H., Yeap, S.K., Kaiser, P., Bejo, M.H., Ideris, A., Tan, S.W. Characterisation on the role of non B lymphocytes during infectious bursal disease virus infection. AIRG 2012: XII Avian Immunology Research Group Meeting, Edinburgh, United Kingdom. Patent, Refer to the attachment 1

Computer software

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Grant Year

Project Title

Role

2010

Immunogenetic analysis of chicken against avian immunosuppressive disease virus for the development of improved vaccines Determination of the Role of Mitochondria in Modulating Chicken Innate Immunity following virulent Newcastle Disease Virus (NDV) infection Analysis the effects of Poultry Assist on lymphoid organ weight and CD3+ T cell populations in village chickens Assessment of the antimetastasis and antiheparanase potential of Flavokawain B in two highly metastatic cancer cell-lines, HepG2 and MDA-MB231. Mechanisms of oncolytic Newcastle disease virus of human cancer cells based on differential transcriptome expression of NDV-treated normal

Co-researcher

Amount Source of fund Status (RM) 6,800,000 HICOE, MOE Completed

Co-researcher

97,000

2012

2013

Co-researcher

ERGS, MOE

On-going

Ancom Crop Care Sdn Bhd.

Completed

Co-researcher

149,640

FRGS, MOE

On-going

Award winner

30,000

MAKNA

On-going

3/4

and cancerous breast cells

2014

Development of microbial Project leader fermentation to enhance bio-absorption of polyphenol compound from Misai Kuching and Roselle extracts Functional genomics of Project leader chicken Intestinal Intraepithelial Natural Killer (IEL-NK) cells following infection with different strains of Infectious Bursal Disease Virus (IBDV) Identification and Co-researcher validation of reference genes for cytokine gene expression responses to Newcastle disease virus infection Genomic sequencing of Co-researcher genotype VII velogenic Newcastle disease virus (NDV) and characterization of the virus immunopathogenesis in specific-pathogen-free chickens Epigenetic profiling of Co-researcher exosomal and intracellular miRNA as therapy target and biomarker of cisplatin resistance in breast cancer stem cell Laboratory scale Co-researcher production and evaluation of circular triple-helix forming oligonucleotide (cTFO) RNA as antiviral agent in cats diagnosed with feline infectious peritonitis disease Understanding the roles of Co-researcher miRNA on various cancer cells through integrative cellulomics and phenomics for diagnostics, therapeutics and prognostic.

100,000

MARDI

On-going

184,700

Putra Grant, UPM

On-going

92,800

Putra Grant, UPM

On-going

184,200

Putra Grant, UPM

On-going

127,200

FRGS, MOE

On-going

252,000

PRGS, MOE

On-going

261,000

TRGS, MOE

On-going

4/4

2015

Development of Novel Recombinant Protein Expression System Using Transgenic Green Unicellular Alga Ankistrodesmus convolutus Corda with HaemagglutininNeuraminidase (HN) Protein of Genotype VII Newcastle Disease Virus as Model Enhancing the therapeutic potential of rAFnewcasle disease virus cancer vaccine Development of in vitro in situ recall assay for cell mediated immunity quantification on vaccinated chicken Production and formulation of recombinant vaccines with enhanced immunogenomic response and immunity for effective mass vaccination against circulating virulent Newcastle disease virus genotype VII

Co-researcher

188.960

e-Science, MOSTI

Sub-project leader

4,171,000 FLAGSHIP DSTIN, MOSTI

On-going

Project leader

159,100

On-going

Co-researcher

1,290,000 TRGS, MOE

e-Science, MOSTI

On-going

On-going

Scopus ID: 22952403200 Scopus H-index: 10 Ad-hoc reviewer contribution: 1. 2. 3. 4. 5. 6. 7. 8. 9.

Food Research International (Elsevier, ISI index) Plant Foods for Human Nutrition (Springer, ISI index) Innovative Food Science and Emerging Technologies (Elsevier, ISI index) Fitoterapia (Elsevier, ISI index) Arabian Journal of Chemistry (Elsevier, ISI index) Natural Product Research (Taylor and Francis, ISI index) Pharmaceutical Biology (Informa Healthcare, ISI index) PERTANIKA (UPM, Scopus index) International Food Research Journal (UPM, Scopus index)

Fields of Specialisation Animal cell culture (primary culture and cell line), flow cytometry, biochemistry, next generation sequencing, tumor immunology, viral immunology, natural product bioactivities, drug discovery, avian immunology.

5/4

Invited speaker: 1. Speaker and trainer for Animal Cell Culture Workshop 2011 - 2014, Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia. 2. IMR NGS and bioinformatics analysis in diagnosis of genetic disease workshop, Grand Season Hotel, Kuala Lumpur, 10 November 2014. Title “Small RNA sequencing: Biomarkers and mechanism profiling.”

Attachment 1 List of Publication: ISI Journal Year 2007

2009

2010

no 1

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2011

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2012

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Title Yeap, S.K., Alitheen, N.B., Ali, A.M., Omar, A.R., Raha, A.R., Suraini, A.A., Muhajir, A.H., 2007. Effect of Rhaphidophora korthalsii methanol extract on human peripheral blood mononuclear cell proliferation and cytolytic activity toward HepG2. Journal of Ethnopharmacology, 114:406-411. PLANT SCIENCES CHEMISTRY, MEDICINAL INTEGRATIVE & COMPLEMENTARY MEDICINE PHARMACOLOGY & PHARMACY Ainul, F.A.B., Alitheen, N.B., Yeap, S.K., Muhajir, H., Siti, A.M.A., Ali, A.M., 2009. A Mouse IgM Monoclonal Antibody Recognizes Breast and Colon Cancer. Hybridoma, 28:199-203. BIOCHEMICAL RESEARCH METHODS BIOTECHNOLOGY & APPLIED MICROBIOLOGY IMMUNOLOGY Yeap, S.K., Alitheen, N.B., Mustafa, S., Abdul Aziz, S., Abdul Rahman, M., Ali, A.M., 2010. Immunomodulatory effects of zerumbone isolated from roots of Zingiber zerumbet. Pakistan Journal of Pharmaceutical Sciences, 23, 75-82. PHARMACOLOGY & PHARMACY Alitheen, N.B., Manaf, A.A., Yeap, S.K., Shuhaimi, M., Nordin, L., Mashitoh, A.R., 2010. Immunomodulatory Effect of Damnacanthal Isolated from Roots of Morinda elliptica. Pharmaceutical Biology, 48, 446-452. MEDICAL LABORATORY TECHNOLOGY PHARMACOLOGY & PHARMACY PLANT SCIENCES Al-Qubaisi, M., Rozita, R., Yeap, S.K., Omar, A.R., Ali, A.M., Alitheen, N.B., 2011. Selective cytotoxicity of goniothalamin against hepatoblastoma HepG2 cells. Molecules, 16:2944-2959. CHEMISTRY, ORGANIC Alitheen, N.B., Oon C.L., Yeap, S.K., Chuan, T.K., Li, H.K., Yong, H.W., 2011. Cytotoxic effects of commercial wheatgrass and fiber towards human acute promyelocytic leukemia cells (HL60). Pakistan Journal of Pharmaceutical Sciences, 24:243250. PHARMACOLOGY & PHARMACY Lam, H.Y., Yeap, S.K., Rasoli, M., Omar, A.R., Yusoff, K., Abd-Aziz, S., Alitheen, N., 2011. Safety and clinical usage of Newcastle disease virus in cancer therapy. Journal of Biomedicine and Biotechnology, 2011, Article ID 718710. BIOTECHNOLOGY & APPLIED MICROBIOLOGY MEDICINE, RESEARCH & EXPERIMENTAL Yeap, S.K., Omar, A.R., Ali, A.M., Ho, W.Y., Beh, B.K.,

IF

Quartile

2.049 Q1 Q2 Q2 Q3

0.411

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0.638 Q4 Q4 Q3 1.988 Q2

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Alitheen, N.B., 2012. Immunomodulatory effect of Rhaphidophora korthalsii on natural killer cell cytotoxicity. Evidence-Based Complementary and Alternative Medicine, 2012, Article ID 786487. INTEGRATIVE & COMPLEMENTARY MEDICINE 9

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Ahmad, Z.A., Yeap, S.K., Ali, A.M., Ho, W.Y., Alitheen, N.B.M., Hamid, M., 2012. ScFv antibody: Principles and clinical application. Clinical and Developmental Immunology, Article ID 980250. IMMUNOLOGY Chong, H.Z., Rahmat, A., Yeap, S.K., Akim, A.M., Alitheen, N.B., Othman, F., Gwendoline-Ee, C.L., 2012. In vitro cytotoxicity of Strobilanthes crispus ethanol extract on hormone dependent human breast adenocarcinoma MCF-7 cell. BMC Complementary and Alternative Medicine, 12, 35. INTEGRATIVE & COMPLEMENTARY MEDICINE, Jazayeri, S.D., Ideris, A., Zakaria, Z., Yeap, S.K., Omar, A.R., 2012. Improved immune responses against avian influenza virus following oral vaccination of chickens with H5 DNA vaccine using attenuated Salmonella typhimurium as carrier. Comparative Immunology, Microbiology & Infectious Diseases, 35, 417-427. IMMUNOLOGY MICROBIOLOGY VETERINARY SCIENCES Lim, K.L., Jazayeri, S.D., Yeap, S.K., Alitheen, N.B.M., Bejo, M.H., Ideris, A., Omar, A.R., 2012. Co-administration of avian influenza virus H5 plasmid DNA with chicken IL-15 and IL-18 enhanced chickens immune responses. BMC Veterinary Research, 8, 132. VETERINARY SCIENCES Chuah, L.O., Yeap, S.K., Ho, W.Y., Beh, B.K., Alitheen, N.B.M., 2012. In vitro and in vivo toxicity of Garcinia or hydroxycitric acid: A review. Evidence-Based Complementary and Alternative Medicine, 2012, Article ID 197920. INTEGRATIVE & COMPLEMENTARY MEDICINE Chong, H.Z., Yeap, S.K., Rahmat, A., Akim, A.M., Alitheen, N.B., Othman, F., Gwendoline-Ee, C.L., 2012. In vitro evaluation of Pandanus amaryllifolius ethanol extract for induction of cell death on non-hormone dependent human breast adenocarcinoma MDA-MB-231 cell via apoptosis. BMC Complementary and Alternative Medicine, 12, 134. INTEGRATIVE & COMPLEMENTARY MEDICINE Ho, W.Y., Yeap, S.K., Ho, C.L., Rahim, R.A., Alitheen, N.B.M., 2012. Hepatoprotective activity of Elephantopus scaber on alcohol-induced liver damage in mice. EvidenceBased Complementary and Alternative Medicine, 2012, Article ID 417953. INTEGRATIVE & COMPLEMENTARY MEDICINE Ho, W.Y., Yeap, S.K., Ho, C.L., Rahim, R.A., Alitheen, N.B., 2012. Development of multicellular tumor spheroid (MCTS) culture from breast cancer cell and a high throughput screening method using the MTT assay. Plos One, 7, e44640. BIOLOGY Yeap, S.K., Ali, N.M., Yusof, H.M., Alitheen, N.B., Beh, B.K., Ho, W.Y., Koh, S.P., Long, K., 2012. Anti-hyperglycemic effect of fermented and non-fermented mung bean extracts on alloxaninduced diabetic mice. Journal of Biomedicine and

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Biotechnology, 2012, Article ID 285430. BIOTECHNOLOGY & APPLIED MICROBIOLOGY MEDICINE, RESEARCH & EXPERIMENTAL Raja-Kumar, V., Yeap, S.K., Ali, A.M., Hamid, M., Alitheen, N.B.M., 2012. Betulinic acid inhibits growth of cultured vascular smooth muscle cells (VSMCs) in vitro by inducing G1 arrest and apoptosis. Evidence-Based Complementary and Alternative Medicine, 2012, Article ID 251362. INTEGRATIVE & COMPLEMENTARY MEDICINE Alitheen, N.B., McClure, S.J., Yeap, S.K., Kristeen-Teo, Y.W., Tan, S.W., McCullagh, P., 2012. Establishment of an in vitro system representing the chicken gut-associated lymphoid tissue. Plos One, 7, e49188. BIOLOGY Ali, N.M., Yeap, S.K., Ho, W.Y., Beh, B.K., Tan S.W., Tan, S.G., 2012. The promising future of chia, Salvia hispanica L.. BioMed Research International, 2013, Article ID 171956. BIOTECHNOLOGY & APPLIED MICROBIOLOGY MEDICINE, RESEARCH & EXPERIMENTAL Ali, N.M., Yusof, H.M., Long, K., Yeap, S.K., Ho, W.Y., Beh, B.K., Koh, S.P., Abdullah, M.P., Alitheen, N.B.M., 2013. Antioxidant and hepatoprotective effect of aqueous extract of germinated and fermented mung bean on ethanol-mediated liver damage. BioMed Research International, 2013, Article ID 693613. BIOTECHNOLOGY & APPLIED MICROBIOLOGY MEDICINE, RESEARCH & EXPERIMENTAL Nigjeh, S.E., Yusoff, F.M., Alitheen, N.B.M., Rasoli, M., Yeap, S.K., Omar, A.R., 2013. Cytotoxic effect of ethanol extract of microalga, Chaetoceros calcitrans and its mechanisms in inducing apoptosis in human breast cancer cell line. BioMed Research International, 2013, Article ID 783690. BIOTECHNOLOGY & APPLIED MICROBIOLOGY MEDICINE, RESEARCH & EXPERIMENTAL Subramani, T., Rathinnavelu, V., Yeap, S.K., Alitheen, N.B., 2013. Influence of mast cells in drug induced gingival overgrowth. Mediators of Inflammation, 2013, Article ID 275172 CELL BIOLOGY IMMUNOLOGY Yeap, S.K., Yusof, H.M., Mohamad, N.E., Beh, B.K., Ho, W.Y., Ali, N.M., Alitheen, N.B., Koh, S.P., Long, K., 2013. In vivo immunomodulation and lipid peroxidation activities contributed to chemopreventive effects of fermented mung bean against breast cancer. Evidence-Based Complementary and Alternative Medicine, 2013, Article ID 708464. INTEGRATIVE & COMPLEMENTARY MEDICINE, Sarah Tan, G.C., Wong, K.M., Pearle-Wong, G.Q., Yeo, S.L., Yeap, S.K., Yiap, B.C., Chong, H.Z. 2013. In vitro cytotoxic and antiproliferative effects of Portulaca oleracea L. methanol extract on breast, cervical, colon and nasopharyngeal cancerous cell lines. Sains Malaysiana, 42, 927-935. MULTIDISCIPLINARY SCIENCES Yeap, S.K., Omar, A.R., Ho, W.Y., Beh, B.K., Ali, A.M., Alitheen, N.B. 2013. Rhaphidophora korthalsii modulates peripheral blood natural killer cell proliferation, cytokine secretion and cytotoxicity. BMC Complementary and Alternative Medicine, 13, 145. INTEGRATIVE & COMPLEMENTARY MEDICINE

Q2 Q2

1.772 Q2

3.73 Q1

2.88 Q2 Q2

2.706 Q2 Q2

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1.877 Q2

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Rahman, H.S., Abdullah, R., How, C.W., Abdul, A.B., Allaudin, Z.N., Othman, H.H., Sawws, M.I., Yeap, S.K., 2013. Zerumbone-loaded nanostructured lipid carrier: Preparation, characterization and anti-leukemia effect. International Journal of Nanomedicine, 8,1-13. NANOSCIENCE & NANOTECHNOLOGY PHARMACOLOGY & PHARMACY Chuah, L.O., Ho, W.Y., Beh, B.K., Yeap, S.K., 2013. Updates on anti-obesity effect of Garcinia origin (-)-HCA. EvidenceBased Complementary and Alternative Medicine, 2013, 751658. INTEGRATIVE & COMPLEMENTARY MEDICINE Yusof, H.M., Ali, N.M., Yeap, S.K., Ho, W.Y., Beh, B.K., Long, K, Koh, S.P., Abd-Aziz, S., Alitheen, N.B., 2013. Hepatoprotective effect of fermented soybean (Nutrient enriched soybean tempeh) on alcohol-induced liver damage in mice. Evidence-Based Complementary and Alternative Medicine, 2013, 274274. INTEGRATIVE & COMPLEMENTARY MEDICINE Akhtar, M.N., Zareen, S., Yeap, S.K., Ho, W.Y., Lo, K.M., Hasan, A., Alitheen, N.B., 2013. Total synthesis, cytotoxic effects of Damnacanthal, Nordamcanthal and related anthraquinone analogues. Molecules, 18, 10042-10055. CHEMISTRY, ORGANIC Nadiah, A., Nadeem, M.A., Ho, W.Y., Yeap, S.K., Alitheen, N.B., 2013. 3-Bromo-1-Hydroxy-9-10-Anthraquinone (BHAQ) inhibits growth and migration of human breast cancer cell lines, MCF-7 and MDA-MB231. Molecules, 18, 10367-10377. CHEMISTRY, ORGANIC Al-Qubaisi, M., Rozita, R., Subramani, T., Omar, A.R., Yeap, S.K., Ali, A.M., Alitheen, N.B., 2013. Goniothalamin selectively induce apoptosis on human hepatoblastoma cells through caspase-3 activation. Natural Product Research, 27, 22216-2218. CHEMISTRY, APPLIED CHEMISTRY, MEDICINAL Zuhaida, A.A., Ali, A.M., Tamilselvan, S., Alitheen, N.B., Hamid, M., Noor, A.M., Yeap, S.K., 2013. Construction of single-chain variable fragment (scFv) against MCF-7 breast cancer cells by phage display technology. Genetics and Molecular Research, 12, 5547-5559. BIOCHEMISTRY & MOLECULAR BIOLOGY GENETICS & HEREDITY Lim, K.L., Jazayeri, S.D., Yeap, S.K., Alitheen, N.B.M., Bejo, M.H., Ideris, A., Omar, A.R., 2013. Antibody and T cell responses induced in chickens immunized with avian influenza virus N1 and NP DNA vaccine with chicken IL-15 and IL-18. Research in Veterinary Science, 95, 1224-1234. VETERINARY SCIENCES Nadiah, A., Ho, W.Y., Yeap, S.K., Akhtar, M.N., Puad, M., Omar, A.R.,, Noorjahan, B.A., 2013. The flavokawains: Uprising medicinal chalcones. Cancer Cell International, 13, 102. ONCOLOGY Rahman, H.S., Rasedee, A., Abdul, A.B., Zeenathul, N.A., Othman, H.H., Yeap, S.K., How, C.W., Ghani, W.N.H.W.A., 2014. Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in human lymphoblastic leukemia cell line. International Journal of Nanomedicine, 9, 1-12.

4.195 Q2 Q1 2.175 Q2

2.175

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NANOSCIENCE & NANOTECHNOLOGY PHARMACOLOGY & PHARMACY Rasoli, M., Yeap, S.K., Tan, S.W., Moeini, H., Ideris, A., Bejo, M.H., Alitheen, N.B.M., Kaiser, P., Omar, A.R., 2014. Alteration in lymphocyte responses, cytokine and chemokine profiles in chicken infected with genotype VII and VIII velogenic Newcastle disease virus. Comparative Immunology, Microbiology & Infectious Diseases, 37, 11-21. IMMUNOLOGY MICROBIOLOGY VETERINARY SCIENCES Subramani, T., Yeap, S.K., Ho, W.Y., Ho, C.L., Omar, A.R., Aziz, S.A., Nik Abdul Rahman, N.M.A., Alitheen, N.B., 2014. Vitamin C suppress cell death in MCF-7 human breast cancer cells induced by tamoxifen. Journal of Cellular and Molecular Medicine, 18, 305-313. CELL BIOLOGY MEDICINE, RESEARCH & EXPERIMENTAL Goh, S.H., Alitheen, N.B.M., Yusoff, F.M., Yeap, S.K., Loh, S.P., 2014. Crude ethyl acetate extract of marine microalga, Chaetoceros calcitrans, induces apoptosis in MDA-MB-231 breast cancer cells. Pharmacognosy Magazine, 10, 1-8. CHEMISTRY, MEDICINAL Abu, N., Ali, N.M., Ho, W.Y., Yeap, S.K., Aziz, M.Y.A., Alitheen, N.B., 2014. Damnacanthal: A promising compound as a medicinal anthraquinone. Anti-Cancer Agents in Medicinal Chemistry, 14, 750-755. CHEMISTRY, MEDICINAL ONCOLOGY Aziz, M.Y.A., Omar, A.R., Subramani, T., Yeap, S.K., Ho, W.Y., Ismail, N.H., Ahmad, S., Alitheen, N.B. 2014. Damnacanthal is a potent inducer of apoptosis with anticancer activity by stimulating p53 and p21 genes in MCF-7 breast cancer cells. Oncology letters, 7, 1479-1484. ONCOLOGY Cheah, Y.K., Cheng, R.W., Yeap, S.K., Khoo, C.H., See, H.S. 2014. Analysis of TP53 gene expression and p53 level of human hypopharyngeal FaDu (HTB-43) head and neck cancer cell Line after microRNA-181a inhibition. Genetics and Molecular Research, 13, 1679-1683. BIOCHEMISTRY & MOLECULAR BIOLOGY GENETICS & HEREDITY Namvar, F., Rahman, H.S., Mohammad, R., Baharara, J., Mahdavi, M., Amini, E., Chartrand, M.S., Yeap, S.K. 2014. Cytotoxic Effect of Magnetic Iron Oxide Nanoparticles Synthesized Via Seaweed Aqueous Extract. International Journal of Nanomedicine, 9, 1-10. NANOSCIENCE & NANOTECHNOLOGY PHARMACOLOGY & PHARMACY Ang, H.Y., Subramani, T., Yeap, S.K., Omar, A.R., Ho, W.Y., Abdullah, M.P., Alitheen, N.B. 2014. Immunomodulatory effects of Potentilla indica and Dendrophthoe pentandra on mice splenocytes and thymocytes. Experimental and Therapeutic Medicine, 7, 1733-1737. MEDICINE, RESEARCH & EXPERIMENTAL Yeap, S.K., Beh, B.K., Ali, N.M., Yusof, H.M., Ho, W.Y., Koh, S.P., Alitheen, N.B., Long, K. 2014. In vivo anti-stress and antioxidant effects of fermented and germinated mung bean. BioMed Research International, 2014, 694842.

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BIOTECHNOLOGY & APPLIED MICROBIOLOGY MEDICINE, RESEARCH & EXPERIMENTAL Sue, M.J., Yeap, S.K., Omar, A.R., Tan, S.W. 2014. Application of PCR-ELISA in Molecular Diagnosis. BioMed Research International, 2014, 653014. BIOTECHNOLOGY & APPLIED MICROBIOLOGY MEDICINE, RESEARCH & EXPERIMENTAL Rahman, H.S., Abdullah, R., Yeap, S.K., Othman H., Max, C., Namvar, F. 2014. Biomedical properties of a natural dietary plant metabolite, Zerumbone, in cancer therapy and chemoprevention trials: A review. BioMed Research International, 2014, 920742. BIOTECHNOLOGY & APPLIED MICROBIOLOGY MEDICINE, RESEARCH & EXPERIMENTAL Yeap, S.K., Beh, B.K., Kong, J., Ho, W.Y., Yusof, H.M., Mohamad, N.E., Hussin, A., Jaganath, I.B., Alitheen, N.B., Jamaluddin, A., Long, K. 2014. In vivo hypocholesterolemic effect of MARDI fermented red yeast rice water extract in high cholesterol diet fed mice. Evidence-Based Complementary and Alternative Medicine, 2014, 707829. INTEGRATIVE & COMPLEMENTARY MEDICINE Ali, N.M., Yusof, H.M., Yeap, S.K., Ho, W.Y., Beh, B.K., Long, K., Koh, S.P., Abdullah, M.P., Alitheen, N.B. 2014. Antiinflammatory and antinociceptive activities of untreated, germinated and fermented mung bean aqueous extract. Evidence-Based Complementary and Alternative Medicine, 2014, 350507. INTEGRATIVE & COMPLEMENTARY MEDICINE Foo, J.B., Yazan, L.S., Tor, Y.S., Armania, N., Ismail, N., Imam, M.U., Yeap, S.K., Cheah, Y.K., Abdullah, R., Ismail, M. 2014. Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathway. BMC Complementary and Alternative Medicine, 14, 197. INTEGRATIVE & COMPLEMENTARY MEDICINE Lam, H.Y., Yusoff, K., Subramani, T., Abd-Aziz, S., Omar, A.R., Yeap, S.K., Alitheen, N.B. 2014. Immunomodulatory effect of Newcastle disease virus AF2240 strain on human peripheral blood mononuclear cell. International Journal of Medical Sciences, 11, 1240-1247. MEDICINE, GENERAL & INTERNAL Abu, N., Akhtar, M.N., Yeap, S.K., Lim, K.L., Ho, W.Y., Zulfadli, A.J., Omar, A.R., Sulaiman, M.R., Abdullah, M., P., Alitheen, N.B., 2014. Flavokawain A induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro. Plos One, 9, e105244. BIOLOGY Rahman, H. S., Rasedee, A., Othman, H. H., Chartrand, M. S., Namvar, F., Yeap, S. K., Samad, N. A., Andas, A. R. J., Nadzri, N. M., Anasamy, T., Ng. K., 2014. Acute Toxicity Study of Zerumbone-Loaded Nanostructured Lipid Carrier on BALB/c Mice Model. BioMed Research International, 2014, 563930. BIOTECHNOLOGY & APPLIED MICROBIOLOGY MEDICINE, RESEARCH & EXPERIMENTAL Suriya, R., Meng, G.Y., Tan, S.W., Yeap, S.K., Ebrahimi, M. 2014. Dietary conjugated linoleic acid supplementation leads to downregulation of PPAR transcription in broiler chickens and reduction of adipocyte cellularity. PPAR Research, 2014, 137652.

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MEDICINE, RESEARCH & EXPERIMENTAL Hosseinpour, M., Abdul, A.B., Rahman, H.S., Abdullah, R., Yeap S.K., Ahmadi, N., Othman, H.H., Chartrand, M.S. 2014. Comparison of apoptotic inducing effect of zerumbone and zerumbone-loaded nanostructured lipid carrier on human mammary adenocarcinoma MDA-MB-231 cell line. Journal of Nanomaterials, 2014, 742738. MATERIALS SCIENCE, MULTIDISCIPLINARY NANOSCIENCE & NANOTECHNOLOGY Rahman, H.S., Rasedee, A., Chartrand, M.S., Othman, H.H., Yeap, S.K., Namvar, F. 2014. Zerumbone induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in jurkat cell line. Natural Product Communication, 9, 1237-1242. CHEMISTRY, MEDICINAL FOOD SCIENCE & TECHNOLOGY Rahman, H.S., Rasedee, A., How, C.W., Zeenathul, A., Chartrand, M.S., Yeap, S.K., Abdul, A.B., Wei, T.S., Othman, H.H., Ajdari, Z., Namvar, F., Palanisamy, A., Fakurazi, S., Mehrbod, P., Daneshvar, N., Begum, H. 2015. Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model. International Journal of Nanomedicine, 10, 1649-1666. NANOSCIENCE & NANOTECHNOLOGY PHARMACOLOGY & PHARMACY Subramani, T., Yeap, S.K., Ho, W.Y., Ho, C.L., Osman, C.P. Ismail, N.H., Rahman, N.M.A.N.A., Alitheen, N.B. 2015. Nordamnacanthal potentiates the cytotoxic effects of tamoxifen in human breast cancer cells. Oncology letters, 9, 335-340. ONCOLOGY Ho, W.Y., Yeap, S.K., Liang, W.S., Beh, B.K., Mohamad, N.E., Alitheen, N.B. 2015. In vitro antioxidant and In vivo hepatoprotective effect on Ethanol-mediated liver damage of spray dried Vernonia amygdalina water extract. Pakistan Journal of Pharmaceutical Sciences, 28, 15-22. PHARMACOLOGY & PHARMACY Yeap, S.K., Beh, B.K., Ali, N.M., Yusof, H.M., Ho, W.Y., Koh, S.P., Alitheen, N.B., Long, K. 2015. In vivo anti-stress and antioxidant effects of virgin coconut oil. Experimental and Therapeutic Medicine, 9, 39-42. MEDICINE, RESEARCH & EXPERIMENTAL Murni, N.S., Dambata, M.S., Yeap, S.K., Froemming, G.R.A., Hermawan, H. 2015. Cytotoxicity evaluation of biodegradable Zn-3Mg alloy toward normal human osteoblast cells. Materials Science and Engineering: C, 49, 560-566. MATERIALS SCIENCE, BIOMATERIALS Yong, C.Y., Yeap, S.K., Goh, Z.H., Ho, K.L., Omar, A.R., Tan, W.S. 2015. Induction of humoral and cell-mediated immune responses by hepatitis B virus epitope displayed on the viruslike particles of prawn nodavirus. Applied and Environmental Microbiology, 81, 882-889. BIOTECHNOLOGY & APPLIED MICROBIOLOGY MICROBIOLOGY Yeap, S.K., Akhtar, M.N., Lim, K.L., Abu, N., Ho, W.Y., Zareen, S., Roohani, K., Ky, H., Tan, S.W., Lajis, N., Alitheen, N.B. 2015. Synthesis of anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell lines. Drug Design, Development and Therapy, 9, 983-992. CHEMISTRY, MEDICINAL

Q3

1.611 Q2 Q3

0.924 Q4 Q3

4.195

Q2 Q1

0.987 Q4

0.950 Q4

0.941 Q4

2.736 Q2

3.952 Q1 Q1

3.026

Q2

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64

65

66

67

68

69

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71

PHARMACOLOGY & PHARMACY Mohamad, N.E., Yeap, S.K., Lim, K.L., Yusof, H.M., Beh, B.K., Tan, S.W., Ho, W.Y., Sharifuddin, S.A., Jamaluddin, A., Long, K., Rahman, N.M.A.N.A., Alitheen, N.B., 2015. Antioxidant effects and restoration of paracetamol-induced liver damage by pineapple vinegar. Chinese Medicine, 10, 3. INTEGRATIVE & COMPLEMENTARY MEDICINE Namvar, F., Rahman, H.S., Mohammad, R. Azizi, S., Tahir, P., Chartrand, M.S., Yeap, S.K., 2015. Cytotoxic effects of biosynthesized Zinc Oxide nanoparticles on murine cell lines. Evidence-Based Complementary and Alternative Medicine, 2015, 593014. INTEGRATIVE & COMPLEMENTARY MEDICINE Ahmadipour, F., Noordin, M.I., Mohan, S., Arya, A., Paydar, M., Looi, C.Y., Keong, Y.S., Siyamak, E.N., Fani, S., Firoozi, M., Yong, C.L., Sukari, M.A., Kamalidehghan, B. 2015. Koenimbin, a natural dietary compound of Murraya koenigii (L) Spreng: inhibition of MCF7 breast cancer cells and targeting of derived MCF7 breast cancer stem cells (CD44 +/CD24-/low): an in vitro study. Drug Design, Development and Therapy, 9, 11931208. CHEMISTRY, MEDICINAL PHARMACOLOGY & PHARMACY Mohamad, N.E., Abu, N., Rahman, H.S., Ky, H., Ho, W.Y., Lim, K.L., How, C.W., Rasedee, A., Alitheen, N.B., Yeap, S.K., 2015. Nanostructured lipid carrier improved in vivo antitumor and immunomodulatory effect of Zerumbone in 4T1 challenged mice. RSC Advances, 5, 22066-22074. CHEMISTRY, MULTIDISCIPLINARY Abu, N., Mohamed, N.E., Yeap, S.K., Lim, K.L., Akhtar, M.N., Zulfadli, A.J., Kee, B.B., Abdullah, M.P., Omar, A.R., Alitheen, N.B. 2015. In vivo anti-tumor and anti-metastatic effects of Flavokawain B in 4T1 breast cancer cell-challenged mice. Drug Design, Development and Therapy, 9, 1401-1417. CHEMISTRY, MEDICINAL PHARMACOLOGY & PHARMACY Tan, B.L., Norhaizan, M.E., Yeap, S.K., Roselina, K., 2015. Water extract of brewers’ rice induce antiproliferation of human colorectal cancer (HT-29) cell lines via the induction of apoptosis. European Review for Medical and Pharmacological Sciences, 19, 1022-1029. Yong, C.Y., Yeap, S.K., Ho, K.L., Omar, A.R., Tan, W.S. 2015. A potential universal vaccine against influenza A virus based on M2e displayed on nodaviral capsid nanoparticles. International Journal of Nanomedicine, 10, 2751-2763. NANOSCIENCE & NANOTECHNOLOGY PHARMACOLOGY & PHARMACY Rasoli, M., Yeap, S.K., Tan, S.W., Roohani, K., Kristeen Teo, Y.W., Alitheen, N.B., Yasmin, A.R., Ideris, A., Bejo, M.H., Kaiser, P., Omar, A.R., 2015. Differential modulation of immune response and cytokine profiles in the bursae and spleen of chickens infected with very virulent infectious bursal disease virus. BMC Veterinary Research, 11, 75. VETERINARY SCIENCES

Q2

2.343 Q1

2.175 Q2

3.026

Q2 Q2

3.708 Q1

3.026 Q2 Q2

0.988 Q4

4.195 Q2 Q1

1.74

Q1

Other publications Year

Event

Index

13 / 4

1

2009

2

3

Zulkifli, Y., Alitheen, N.B., Raha, A.R., Yeap, S.K., Marlina, Son, R., Nishibuchi, M., 2009. Antibiotic Resistance and Plasmid Profiling of Vibrio parahaemolyticus Isolated from Cockles in Padang Indonesia. International Food Research Journal, 16:53-58. Zulkifli, Y., Alitheen, N.B., Son, R., Raha, A.R., Samuel, L., Yeap, S.K., Nishibuchi, M., 2009. Random amplified polymorphic DNA-PCR and ERIC PCR analysis on Vibrio parahaemolyticus isolated from cockles in Padang, Indonesia. International Food Research Journal, 16:141-150. Zulkifli, Y., Alitheen, N.B., Son, R., Yeap, S.K., Lesley, M.B., Raha, A.R., 2009. Identification of Vibrio parahaemolyticus isolates by PCR targeted to the toxR gene and detection of virulence genes. International Food Research Journal, 16:289-296.

Scopus

Scopus

Scopus

4

Ho, W.Y., Ky, H., Yeap, S.K., Raha, A.R., Omar, A.R., Ho, Scopus C.L., Alitheen, N.B., 2009. Traditional practice, bioactivities and commercialization potential of Elephantopus scaber Linn. Journal of Medicinal Plants Research, 3, 1212-1221.

5

Tan, B.K., Alitheen, N.B., Yeap, S.K., Ali, A.M. Mawardi, R., 2009. Cytotoxic effect of 2’,3’-epoxy isocapnolactone and 8hydroxyisocapnolactone-2’3’-diol isolated from Micromelum minutum (G.Forst.) Wight & Arn. in human T-lymphocyte leukemia CEM-SS cells. African Journal of Biotechnology, 8:4632-4641. Alitheen, N.B., Yeap, S.K., Shuhaimi, M., Abdul Manaf, A., Mashitoh, A.R., and Nordin, L., 2010. Cytotoxic Effect of Damnacanthal, Nordamnacanthal, Zerumbone and Betulinic Acid Isolated from Malaysian Plant Sources. International Food Research Journal, 17, 711719.

6

2010

Scopus

Scopus

7

Lam, H.Y., Yeap, S.K., Alitheen, N.B., Ho, W.Y., Omar, Scopus A.R., Yusoff, K., Suraini, A.A., Ky, H., 2010. Understand the role of natural killer. American Journal of Immunology, 6:5461.

8

Yeap, S.K., Ho, W.Y., Beh, B.K., Liang, W.S., Ky, H., Yousr, A.H.N., Alitheen, N.B., 2010. Vernonia amygdalina, an ethnoveterinary and ethnomedical used green vegetable with multiple bio-activities. Journal of Medicinal Plants Research, 4:2787-2812. Faujan, N.H., Alitheen, N.B., Yeap, S.K., Ali, A.M., Muhajir, A.H., Ahmad, F.B.H., 2010. Cytotoxic effect of betulinic acid and betulinic acid acetate isolated from Malaysia plant on human myeloid leukemia (HL60) cell line. African Journal of Biotechnology, 9:6387-6396.

9

10

11

2011

Scopus

Scopus

Yeap, S.K., Rahman, M.B.A., Alitheen, N.B., Ho, W.Y., Scopus Omar, A.R., Beh, B.K., Ky, H., 2011. Evaluation of Immunomodulatory effect: Selection of the correct targets for immunostimulatory study. American Journal of Immunology, 7: 17-23. Alitheen, N.B., Yeap, S.K., Faujan, N.H., Ho, W.Y., Beh, Scopus B.K., Mashitoh, A.R., 2011. Leukemia and Therapy. American Journal of Immunology, 7, 54-61.

12

Yeap, S.K., Alitheen, N.B.M., Ho, W.Y., Omar, A.R., Ali, A.M., Beh, B.K., Yousr, A.H.N., 2011. Immunomodulatory role of Rhaphidophora korthalsii methanol extract on human peripheral blood mononuclear cell proliferation, cytokine secretion and cytolytic activity. Journal of Medicinal Plants Research, 5:958-965.

13

Ho, W.Y., Yeap, S.K., Ho, C.L., Rahim, R.A., Alitheen, Scopus N.B., 2011. Elephantopus scaber induces cytotoxicity in MCF-7 human breast cancer cells via p53-induced apoptosis. Journal of Medicinal Plants Research, 5: 5741–5749.

Scopus

14 / 4

Yeap, S.K., Omar, A.R., Ho, W.Y., Beh, B.K., Ali, A.M., Alitheen, N.B., 2011. Immunomodulatory effect of Rhaphidophora korthalsii on mice splenocyte, thymocyte and bone marrow cell proliferation and cytokine expression. African Journal of Biotechnology, 10:10744-10751.

14

15

2012

16

Scopus

Mashitoh, A.R., Yeap, S.K., Ali, A.M., Faujan, A., Suhaimi, Scopus M., Ng, M.K., Lam, H.Y., Alitheen, N.B., 2012. Immunomodulatory effects of betulinic acid isolation from the bark of Melaleuca cajuputi. Pertanika, 35, 103-116. Ky, H., Yeap, S.K., Napis, S.B., 2012. The best method for Scopus isolated total RNA from durian tissues. International Food Research Journal, 19, 1181-1183.

17

Ho, W.Y., Liang, W.S., Yeap, S.K., Beh, B.K., Yousr, Scopus A.H.N., Alitheen, N.B., 2012. In vitro and in vivo antioxidant activity of Vernonia amygdalina water extract. African Journal of Biotechnology, 11:4090-4094.

18

Ng, M.K., Alitheen, N.B., Noaman, Y.A., Cheah, Y.K., Yeap, S.K., 2012. Bioactivity studies and chemical constituents of Murraya paniculata (Linn) Jack. International Food Research Journal, 19, 13071312. Yeap, S.K., Liang, W.S., Beh, B.K., Ho, W.Y., Yousr, A.N., Alitheen, N.B., 2013. In vivo antidiabetic and acute toxicity of spray-dried Vernonia amygdalina water extract. International Food Research Journal, 20, 613616.

Scopus

Alitheen, N.B., Yeap, S.K., Ho, W.Y. 2009. 7. Elephantopus scaber Linn.: From ground to the clay pot. RPMP vol. 27. Ethnomedicine: source & Mechanism I. pg. 123-143. Yeap, S.K., Ho, W.Y., Faujan, N.H., Ali, A.M., Alitheen, N.B. 2013. Betulinic acid and its derivatives: The potential anticancer agents. In: Bioactive Phytochemicals: Perspectives for Modern Medicine Vol. 2. pg. 83-92.

Book Chapter

19

2013

20

2009

21

2013

Scopus

Book Chapter

Patent 1. Alitheen, N.B.M., Lam, H.Y., Yusoff, K., Aziz, S.A., Yeap, S.K. 2010. Newcastle disease virus activated human peripheral blood mononuclear cells and their use in cancer therapy. Malaysia Patent Pending. Application no: PI2010700088 2. Long, K., Koh, S.P., Alitheen, N.B.M., Yeap, S.K., 2012. Composition for multiple health benefits and methods thereof. Malaysia Patent Pending. Application no: PI2012700032. 3. Rasedee, Heshu, S.R., Ahmad, B.A., How, C.W., Yeap, S.K. 2013. A composition for treating leukemia. Malaysia Patent Pending. Application no: PI2013700213. 4. Tan, W.S., Ho, K.L., Yong, C.Y., Goh, Z.H., Abdul, R.O., Yeap, S.K. 2014. Virus-like particles of Macrobrachium rosenbergii Nodavirus capsid as a carrier for immunogenic components. Malaysia Patent Pending. Application no: PI2014702540. Seminar and Workshop 1.

Alitheen, N.B., Yeap, S.K., Ho, W.Y. Development of Multicellular tumor spheroids (MCTS) culture system to investigate the effect of activated Natural Killer (NK) Cells. Workshop on Biotechnology R&D Projects Evaluation and Monitoring, MOSTI and Biotek Malaysia, 8-10 June 2008

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2.

3.

4.

5.

6. 7.

BNet Business Networking Session 2010 by Frost & Sullivan Malaysia Sdn. Bhd and Malaysia Biotechnology Corporation Sdn Bhd, Berjaya Times Square Hotel Kuala Lumpur, Malaysia, 15 December 2010. “Biotech Today” Seminar by Shearn Delamore & Co and Malaysian Biotechnology Corporation Sdn Bhd, Wisma Hamzah-Kwong Hing, Kuala Lumpur, Malaysia, 14 October 2010. Seminar on Guidelines on Tax Incentives Accorded to BioNexus Status Companies by Malaysia Biotechnology Corporation Sdn Bhd, Melia hotel, Kuala Lumpur, Malaysia, 22 June 2010. Tax Seminar on Import Duty and Sales Tax Exemption, and Malaysian Customs Import/Export Legislation and Procedures by Malaysian Biotechnology Corporation Sdn Bhd, 25 October 2010 Basic Licensing Workshop by Malaysian Biotechnology Corporation Sdn Bhd, Hang Tuah Room, Level 6, Le Meridien Hotel, Kuala Lumpur, Malaysia, 28 July 2010 Good Manufacturing Practices (GMP) seminar by NSF International and Malaysian Biotechnology Corporation Sdn Bhd, Hotel Istana, Kuala Lumpur, Malaysia, 16 June 2010

Conference

1

Year 2006

2

3

2007

4

2008

5

2009

6

7

8 9 10

2010

Event Alitheen, N.B., Mashitoh, A. R., Azrina, A., Yeap, S.K., Shuhaimi, M., Nordin, L., Ali, M.A. Cytotoxicity and immunomodulatory activity of Damnacanthal and Nordamnacanthal from roots of Morinda elliptica. Trends in Biotechnology 3, Marriott Putrajaya. 5-6 September 2006. Noorjahan, B.M.A., Azrina, B.M.A., Mashitoh, A.R., Yeap, S.K., Ali, M.A. Cytotoxicity and immunomodulatory effects of medicinal plants crude extracts. Trends in Biotechnology 3, Marriott Putrajaya. 5-6 September 2006. Ho, K.L., Alitheen, N.B., Yeap, S.K. Proliferation effect of wheatgrass and Organic Fibers’ Methanol Extracts on Normal and cancerous Blood Cells. 18th Intervarsity Biochemistry seminar, University Malaya, Kuala Lumpur. 17 Mac 2007 Lam, H.Y., Yeap, S.K., Alitheen, N.B. Cytotoxicity and anti-proliferation effcets of Elephantopus type plant extract and NF extract on MCF-7 cells. 19th Intervarsity Biochemistry seminar, UTAR, Petaling Jaya, Selangor. 22 Mac 2008 Tee, S.Y., Alitheen, N.B., Ho, W.Y., Lam, H.Y., Ng, M.K., Yeap, S.K. Cytotoxic Study of Hot Water Extract of a Rutaceae Plant on Human Breast Adenocarcinoma, MCF-7. 20 th Intervarsity Biochemistry seminar, Faculty of Medicine and Health Sciences, UPM. 21st March 2009. Lam, H.Y., Yeap, S.K., Khatijah, Y., Suraini, A.A., Omar, A.R., Alitheen, N.B. Immunoregulatory effects of NDV AF2240 strain on the cytolytic activity of PBMC against MCF-7 cells. Newcastle Disease Virus Colloquium 2009, Corus Paradise Resort, Port Dickson. 21-22 August 2009 Chuah, L.O., Foo, H.L., Raha, A.R., Alitheen, N.B., Loh, T.C., Yeap, S.K. Cytotoxic Effect of Metabolites Derived from Lactobacillus plantarum. International Congress of Malaysian Society for Microbiology, Park Royal Hotel, Penang. 1-4 December 2009. Bio Jom Heboh, Bukit Jalil, Selangor, Malaysia, 11-12 December 2010. BioMalaysia Conference by Malaysia Biotechnology Corporation, Kuala Lumpur Convention Center, Malaysia 1-3 November 2010. BioFunding 2010: Biotechnology Investment Conference by Malaysian Biotechnology Corporation Sdn Bhd, Le Meridien Hotel Kuala Lumpur, 20-21 July 2010.

Level National

National

National

National

National

National

National

National National National

16 / 4

11

2011

12

13

14

15

2012

16

17

18

19

20

21

2013

Ho Wan Yong, Noorjahan Banu Alitheen, Raha Abdul Rahim, Ho Chai Ling, Yeap Swee Keong. Cytotoxic Effect of Elephantopus scaber Ethanol Extract on MCF-7 Human Breast Cancer Cell Line. “Advances In Drug Development For A Better Well-Being” 25th Scientific Meeting of The Malaysian Society Of Pharmacology And Physiology, 25-26 May 2011, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia Noorjahan Banu Alitheen, Kristeen Teo Ye Wen, Yeap Swee Keong, Ho Wan Yong, Beh Boon Kee, Woon San Liang. Vernonia amygdalina: A Source of Antimicrobial Agent or Just another Fairy Tale? “Advances In Drug Development For A Better Well-Being” 25th Scientific Meeting of The Malaysian Society Of Pharmacology And Physiology, 25-26 May 2011, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia Ho, W.Y., Alitheen, N.B., Rahim, R.A., Ho, C.L., Yeap, S.K. Synergism between Elephantopus scaber and tamoxifen against human breast cancer cells. International Conference on Natural Products 2011, Palm Garden Hotel, IOI Resort Putrajaya, Malaysia. Aziz, M.Y., Alitheen, N.B., Yeap, S.K., Omar, A.R., Ismail, N.H., Cytotoxic effects of Damnacanthal and combination Damnacanthal with Doxorubicin on human breast cancer cell line (MCF-7). International Conference on Natural Products 2011, Palm Garden Hotel, IOI Resort Putrajaya, Malaysia. Omar, A.R., Rasoli, M., Moeini, H., Yeap, S.K., Kaiser, P., Bejo, M.H., Ideris, A., Tan, S.W. Characterisation on the role of non B lymphocytes during infectious bursal disease virus infection. Abstract from AIRG 2012: XII Avian Immunology Research Group Meeting, Edinburgh, United Kingdom. Verusingam, N.D., Boo, L., Yeap, S.K., Chong, L.K., Cheong, SK., Ong, H.K. Characterisation of induced pluripotent stem cells (iPSCs) derived from prostate and breast cancer cell lines. Genetic and Genomic Medicine: Working together towards health for all, 10 th Asia-Pacific Conference on Human Genetics 2012. Heshu, S.R., Rasedee, A., Ahmad, B.A., Hemn, H.O., Zeenathul, N.A., How, C.W., and Swee, K.Y. 2012. In vitro Ultra-morphological Assessment of Apoptosis Induced by Zerumbone Loaded Nanostructured Lipid Carrier (ZER-NLC) on Jurkat Lymphoblastoid Cells. Proceedings of 21st Scientific Conference of the Microscopy Society of Malaysia (EMSM) 2012. 22nd -24th Nov 2012, Renaissance Kota Baharu Hotel, Kota Baharu, Kelantan. Heshu, S.R., Rasedee, A., Ahmad, B.A., Hemn, H.O., Zeenathul, N.A., How, C.W., and Swee, K.Y. 2012. Zerumbone Induces Apoptosis in Human Acute Leukaemia Jurkat T-Cell Line. Proceedings of International Conference on One Health and 24th VAM Congress 2012. Organized by Veterinary Association of Malaysia (VAM). 21 st-23rd Sep 2012. Putrajaya Marriott Hotel/IOI Resort/Putrajaya/Malaysia. Heshu, S.R., Rasedee, A., Ahmad, B.A., Zeenathul, N.A., Farideh, N., Hemn, H.O., Swee, K.Y, and How, C.W. (2013). Zerumbone, a Natural Dietary Sesquiterpene from Zingiber zerumbet for Leukaemia Therapy In Vitro. Proceeding of International Conference on Natural Products (ICNP). 29thMalaysian Annual Natural Product Seminar. pp: 58. 4th – 6th March 2013. Shah Alam Convention Center (SACC), Selangor, Malaysia. Heshu, S. R., Rasedee, A., Ahmad Bustamam, A., Yeap, S.K., Hemn, H. O., Zeenathul, N. A., and How, C. W . In vitro Response of Jurkat Lymphoblastoid Cells to the Growth Inhibitory Effects of Pure Zerumbone Crystals of Zingiber zerumbet. Proceeding of International Conference on Advances in Medical Science. 16 th – 18th April 2013. Impiana Hotel, KLCC, Kuala Lumpur, Malaysia. (Oral presentor). Heshu, S. R., Rasedee, A., Ahmad Bustamam, A., Yeap, S.K., Hemn, H. O., Zeenathul, N. A., and How, C. W . The Growth

University

University

National

National

International

National

National

National

National

National

National

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Suppressing Effects of Zerumbone on Jurkat Cell Involve Induction of Apoptosis and Caspase Activation. Proceeding of International Conference on Advances in Medical Science. 16th – 18th April 2013. Impiana Hotel, KLCC, Kuala Lumpur, Malaysia. (Poster presentor).

Awards

1

Year 2010

2

3

2011

4

2012

5

6

7

8

2013

Event Asmah, R., Chong, H.Z., Abdah M.A., Alitheen, N.B., Fauzi, O., Gwendoline, E.C.L., Yeap S.K. Cancer protection properties from Pandanus amaryllifolius. PRPI, UPM 2010, Pusat Kebudayaan dan Kesenian Sultan Salahuddin Abdul Aziz Shah, UPM, Serdang, 20-22 July 2010. Noorjahan Banu Alitheen, Kristeen Teo Yee Wen, Yeap Swee Keong, Abdul Rahman Omar, Abdul Manaf Ali, Suraini Abdul Aziz, Ho Wan Yong, Beh Boon Kee. Rhaphidophora korthalsii methanol extract as a potential immunomodulatory in human. PRPI, UPM 2011, Pusat Kebudayaan dan Kesenian Sultan Salahuddin Abdul Aziz Shah, UPM, Serdang, 19-21 July 2010. Noorjahan Banu Alitheen, Mothanna Al-Qubaisi, Rozita Rosli, Yeap Swee Keong, Abdul Rahman Omar, Abdul Manaf Ali. Goniothalamin: a potential hepatoblastoma chemotherapy adjuvant. PRPI, UPM 2011, Pusat Kebudayaan dan Kesenian Sultan Salahuddin Abdul Aziz Shah, UPM, Serdang, 19-21 July 2010. Noorjahan Banu Alitheen, Lam Han Yuen, Yeap Swee Keong, Datin Khatijah Yusoff, Abdul Rahman Omar, Suraini Abdul Aziz, Beh Boon Kee, Tamilselvan Subramani. Local Newcastle Disease Virus (NDV) activated human peripheral blood mononuclear cells (PBMC): Their potential use in cancer therapy. PRPI, UPM 2012, Pusat Kebudayaan dan Kesenian Sultan Salahuddin Abdul Aziz Shah, UPM, Serdang, 17-19 July 2012. Noorjahan Banu Alitheen, Yeap Swee Keong, Ho Wan Yong, Liang Woon San, Beh Boon Kee, Kristeen Teo Ye Wen and Nurul Elyani Mohamad. In vitro and in vivo antioxidant activity of spray dried Vernonia amygdalina water extract. PRPI, UPM 2012, Pusat Kebudayaan dan Kesenian Sultan Salahuddin Abdul Aziz Shah, UPM, Serdang, 17-19 July 2012. Boo, L., Verusingam, N.D., Yeap, S.K., Omar, A.R., Alitheen, N.B., Chong, L.K., Cheong, S.K., Ong, H.K. Genomic Instability, microsatellite instability and hypermethylation patterns of specific promoter regions in breast and prostate cancer cell lines and their spheroid derivatives. Genetic and Genomic Medicine: Working together towards health for all, 10th Asia-Pacific Conference on Human Genetics 2012. Long, K., Koh, S.P., Jamaluddin, A., Alitheen, N.B., Yeap, S.K., Ali, N.M., Yusof, H.M., Beh, B.K., 2013. MyG-Mung BeanTM- New and highly nutritious tempeh. Malaysia Technology Expo (MTE 2013), 21-23 February 2013, PWTC. Kamariah, L., Noorjahan, B.A., Yeap, S.K., Koh, S.P., Anisah, J., Beh, B.K., Norlaily, M.A., Hamidah, M.Y., Ainaa, A.K., 2013. MyG-Mung Bean- New generation

Achievement Bronze medal

Level University

Bronze medal

University

Bronze medal

University

Gold medal

University

Silver medal

University

Gold medal

National

Silver medal

National

Gold medal

National

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9

10

2014

functional food product with multiple health benefits. ITEX, 9-11 May 2013. KLCC, Kuala Lumpur, Malaysia. MAKNA cancer research award 2013 “Mechanisms of oncolytic Newcastle disease virus of human cancer cells based on differential transcriptome expression of NDVtreated normal and cancerous breast cells” Koh Soo Peng, Kamariah Long, Syazwani Abdul Hamid, Zahiah Mohamed Amin, Tan Chin Ping, Yeap Swee Keong, 2014. A new microencapsulating agent with improved functionality. Malaysian Agricultural Innovation Challenge (MAGIC) 2014, Malaysia Agro Exposition Park Serdang (MAEPS), 6-8 November 2014.

Grant

National

Gold medal

National

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