Monday, May 18th, 2015 7:00 - con.

Registration, Refreshments & Exhibition Tour

8:00 - 09:30 Oral Presentations- Three Parallel Sessions 8:00 - 09:30 Hall A – Oral Presentation Session 1: Embryology / ART Chairs: Pavel Itsykson, Eliahu Levitas, Dvora Strassburger, Iris Har Vardi 8:00

Time-Lapse versus bench incubator - a prospective randomized study comparing embryo outcome of sibling oocytes Danielle Hadari, Gidoni Y.S., Kasterstein E., Raziel A., Strassburger D., Bern O., Ben-Ami I., Komarovsky D., Barkat Y., Maslansky B., Ron-El R. IVF and Infertility unit Assaf Harofeh Medical Center, Zerifin, Israel

8:12

The influence of sperm concentration used for ICSI in the laboratory on the outcome of the ART cycle Shevach Friedler1, Cohen O.2, Liberty G.1, Latzer T.1, Saar-Ryss B.1, Rabinson Y.1, Marchak E.1, Meltzer S.1 Infertility and IVF Unit, Barzilai Medical Center, Faculty of Medicine and Health Sciences, 1 Ben-Gurion University of the Negev , Research & Development Authority, Barzilai Medical Center, 2 Ashkelon, Israel

8:24

High level of C-Reactive Protein (CRP) in women undergoing IVF is associated with low quality embryos Einat Haikin Herzberger, Miller N., Ghetler Y., Amichay K., Berkovitz A., Shulman A., Wiser A. IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel, affiliated with the Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel

8:36

Blastocyst formation rate in embryos not suitable for transfer or freezing. Retrospective study Genia Ziskind, Silberman M., Avraham H., Navon O., Frenkel P., Khoury S., Bahar D., Cohen M., Calderon I. ART Unit, Dept of Obstetrics and Gynecology, Bnai-Zion Medical Center, Technion, Haifa, Israel

8:48

The effect of culturing at reduced oxygen tension on embryo morphokinetic parameters and cycle outcome Roni Garor, Ben-Haroush A., Margalit T., Kotler N., Shefer D., Krasilnikov N., Tzabari M., Shufaro Y., Fisch B., Sapir O. Infertility and IVF Unit, Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

1

9:00

The value of sequential embryo transfer as a therapeutic approach in IVF patients with repeated implantation failure Sarit Allouche, Weissman A., Shalev A., Nahum H., Horowitz E., Ravhon A., Steinfeld Z., Yusofov H., Levran D., Farhi J. IVF Unit, Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

8:00 - 9:30

Hall B – Oral Presentation Session 2: Ovary Basic Chairs: Ruth Shalgi, Ariel Revel, Irit Granot, Michal Yunish

8:00

Alterations of myeloid cell populations in human follicular fluid correlate with ovarian response to gonadotropins Ofer Fainaru, Karchovski Shoshan E., Hantisteanu S., Segal M., Paz G., Limonad O., Michaeli M., Shalom Paz E., Rothfarb N., Ellenbogen A. IVF Unit and Laboratory of Reproductive Immunology, Hillel Yaffe Medical Center, Hadera, Israel

8:12

BPA exposure and granulosa Cell steroidogenesis: An in vitro human study Abdallah Mansour1, Adir M.1,2, Yerushalmi G.1,2, Hourvitz A.1,2, Gitterman H.1,2, Yung Y.1,2, Orvieto R.1,2, Machtinger R.1,2 1

Infertility and IVF Unit, Department of Obstetrics and Gynecology, Sheba Medical Center , Sackler 2 School of Medicine, Tel-Aviv University, Tel-Aviv, Israel

8:24

Vasorin regulates ovulation capacity and is involved in determining the ovarian reserve Nitzan Rimon-Dahari, Heinemann-Yerushalmi L., Galiani D., Kalich-Philosoph L., Dekel N. Departemet of Biological Regulation, The Weizmann Institute of Science, Rehovot, Israel

8:36

Serum circulating microRNAs as potential biomarkers of human ovulation Iris Eisenberg1, Goldman-Wohl D.1, Greefield C.1, Pozilov S.1, Hurwitz A.2, Bdolah Y.2, Haimov-Kochman R.1,2, Yagel S.1,2, Imbar T.1,2 The Magda and Richard Hoffman Center for Human Placenta Research, Hadassah - Hebrew 1 University Medical Center, Jerusalem, Israel , Department of Obstetrics and Gynecology, 2 Hadassah Mt. Scopus - Hebrew University Medical Center, Jerusalem, Israel

8:48

microRNA-210 as a mediator of hypoxic responses in human granulosa cells Tal Imbar1,2, Eisenberg I.2, Shrestha K.3, Oyesiji Adepeju E.3, Hurwitz A.1, Greefield C.2, Goldman-Wohl D.2, Haimov-Kochman R.1,2, Yagel S.1,2, Meidan R.3 Department of Obstetrics & Gynecology, Hadassah Mt. Scopus - Hebrew University Medical 1 Center, Jerusalem, Israel , The Magda and Richard Hoffman Center for Human Placenta 2 Research, Hadassah-Hebrew University Medical Center, Jerusalem, Israel , Department of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food, and Environment, The Hebrew 3 University of Jerusalem, Rehovot, Israel

2

9:00

Prostaglandin transporter (PGT) regulation of PGE2 signaling is essential for ovulation Gil Yerushalmi1, Markman S.1, Yung Y.1, Maman E.1, Aviel-Ronen S.2, Orvieto R.1, Hourvitz A. 1 IVF Unit and Reproduction Lab, Department of Obstetrics and Gynecology, Sheba Medical Center, 1 Tel Hashomer, affiliated with the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel , Department of Pathology, Sheba Medical Center, Israel; Talpiot Medical Leadership Program, 2 Sheba Medical Center, Israel

9:12

The popeye domain containing (POPDC) genes seem to have a minor role in the murine ovary Ronit Abir, Eisner M., Schlesinger H., Younis A., Lasman N., Fisch B., Kessler-Icekson G. Infertility & IVF Unit, Beilinson Women Hospital, Rabin Medical Center, Petach Tikvah, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv and Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

8:00 - 9:30

Hall C – Oral Presentation Session 3: Fertility Preservation Chairs: Ilan Cohen, Orna Bern, Ronit Abir, Medeia Michaeli

8:00

Extracellular-like matrices for culturing human primordial follicles Assiel J. Younis, Fisch B., Zahalka M.A., Ben-Haroush A., Shachar M., Gabbay-Benziv R., Abir R. Infertility and IVF Unit, Beilinson Women Hospital, Rabin Medical Center, Petach Tikva, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, Sami Shamoon College of Engineering, The Felsenstein Medical Research Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel- Aviv, Israel

8:12

Attempts to improve human ovarian tissue grafting with bioengineered tobacco plant line pure virgin recombinant human collagen Dana Stav1, Fisch B.1, Kirshner M.1, Younis A. J.1, Zahalka M. A.2, Ben-Haroush A.1, Gabbay-Benziv R.1, Abir R.1 Infertility and IVF Unit, Beilinson Women Hospital, Rabin Medical Center, Petach Tikva, Sackler 1 Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel , The Felsenstein Medical Research 2 Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

8:24

Title: Combined procedure of immature oocyte collection and ovarian tissue cryopreservation for fertility preservation, yield and outcome Alon Kedem, Yerushalmi G., Raanani H., Orvieto R., Hourvitz A., Meirow D. IVF Unit, Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Israel

3

8:36

Anti Mullerian Hormone (AMH) co-treatment to prevent chemotherapyinduced follicle activation and loss Hadassa Roness, Derech-Haim S., Gavish Z., Meirow D. Chaim Sheba Medical Center, Tel-Hashomer, Israel

8:48

Effects of Tamoxifen on endometrial receptivity in young breast cancer patients Zohar Gavish, Derech-Haim S., Meirow D. Center for Fertility Preservation, Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel

9:00

In vitro induction of spermatogenesis from tests of cyclophosphamidetreated sexually immature mice Bat-Chen Amanu1, Karpel O.1, Lunenfeld E.2, Huleihel M.1,3 The Shraga Segal Dep. of Microbiology, Immunology and Genetics, Faculty of Health Sciences, 1 Ben-Gurion University of the Negev, Beer Sheva, Israel , Dep. OB/GYN, Soroka Medical Center, The Center of Advanced Research and Education in Reproduction (CARER), and Faculty of 2 Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel , The Center of 3 Advanced Research and Education in Reproduction (CARER)

9:12

Novel panel of tests to increase the safety of ovarian tissue transplantation in high risk patients Raanani Hila, Derech-Haim S., Rechavi G., Amariglio N., Cohen Y., Aviel-Ronen S., Gavish Z., Meirow D. Chaim Sheba Medical Center, Tel-Hashomer, Israel

8:54-05:00

9:30- 9:55

Golan Hall – Session 4: Nursing Separate Program

‫מושב סיעוד‬ ‫תוכנית בנפרד‬

Exhibition & Refreshments

4

9:55-11:50

Hall A Plenary Session 1 :‫ברכות‬

9:55-10:10

‫יו"ר איל"ה‬ - ‫פרופ' פואד עאזם‬ ‫ נאונטולוגיה וגנטיקה‬,‫יו"ר המועצה הלאומית לרפואת נשים‬ - ‫פרופ' אליעזר שלו‬ ‫ יו"ר האיגוד הישראלי למיילדות וגינקולוגיה‬- ‫פרופ' איתן לוננפלד‬ 10:10-11:50 Invited Speakers Chairs: Amir Wiser, Ron Hauser 10:10

The relationship of reproductive aging to generalized aging Prof. David Keefe Professor and Chairman of Obstetrics and Gynecology; Departments of Obstetrics and Gynecology (Obs/Gyn) and Cell Biology, NYU, USA

11:00

The IVF in the year 2020? Prof. Christophe Blockeel Kliniekhoofd, Centrum voor Reproductive Genneeskunde, Universitair Ziekenhuis Brussel, Belgium

11:50- 12:15 Exhibition & Refreshments

12:15- 14:30 Hall A Plenary Session 2 Chairs: Benny Fisch, Ofer Fainaru 12:15

Selecting chromosomally normal embryos by the embryoscope Prof. Dalit Ben-Yosef Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel

12:30

Egg freezing : Hope or Hype ? Prof. Daniel Seidman Infertility and IVF department, Sheba Medical Center, Tel-Hashomer, Israel

12:45

‫מסד הנתונים הלאומי למחזורי טיפול בהפריה חוץ גופית – תמונת מצב‬ ‫גבע‬-‫פרופ' ליאת לרנר‬ ‫ ישראל‬,‫אביב‬-‫אוניברסיטת תל‬

5

13:00-13:45 Award Papers Presentations Chair: Shevach Friedler 13:00

Live births and pregnancy rates following transplantation of frozen-thawed ovarian tissue using micro-organ technique Jennia Michaeli1, Azem F.2, Eizenman E.3, Mitrani E.4, Bloch M.3, Revel A.3

1

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel , Department of Obstetrics and Gynecology, Lis Maternity Hospital, Tel-Aviv Sourasky Medical 2 Center and The Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel , Department of 3 Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel , Department of Cell and Developmental Biology, Institute of Life Sciences, The Hebrew University 4 of Jerusalem, Jerusalem, Israel

13:15

The capacity to induce generation of premeiotic and meiotic cells from biopsies without sperm from nonobstructive azoospermic and klinefelter syndrome patients were different under in vitro culture conditions Maram Azab1, Lunenfeld E.2, Levitas E.2, Fisch B.3, Pinkass H.3, Stein A.3, Younis J. S.4, Bar-Ami S.4, Orvieto R.5, Huleihel M.1,6 The Shraga Segal Dep. of Microbiology, Immunology and Genetics, Faculty of Health Sciences, 1 Ben Gurion University of the Negev, Beer Sheva , Fertility and IVF Unit, Dep. OB/GYN, Soroka Medical Center and The Center of Advanced Research and Education in Reproduction (CARER), 2 Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva , Male Infertility & Sperm Bank, Helen Schneider Hospital for Women, Rabin Medical Center, Beilinson Hospital, 3 Petach Tikva, Sackler Faculty of Medicine, Tel Aviv University,Tel-Aviv, Israel , Reproductive Medicine Unit, Dep. OB/GYN, Poriya Medical Center, Tiberias; Faculty of Medicine in Galilee, Bar4 5 Ilan University , Dep. OB/GYN, Barzilai Medical Center, Ashkelon , The Center of Advanced 6 Research and Education in Reproduction (CARER)

13:30

Mitochondrial DNA load does not correlate with aneuploidy in cleavage stage human embryos Gheona Altarescu, Herskovitz Y., Weinberg-Shukron A., Zeligson S., Kort D., Farhi E., Indig-Elharar H., Kirshberg S., Eldar-Geva T., Zeevi D. A. Medical Genetics Institute, ZOHAR PGD Unit, Shaare Zedek Medical Center, Jerusalem, Israel

13:45-14:30

‫ טיפולי פריון חסרי תוחלת‬-‫מושב וועדת אתיקה בנושא‬ ‫ פרופ' נרי לאופר‬- ‫יו"ר‬

14:30- 15:30 Lunch

16:00-17:00 Round Table Discussion Galil Hall Prof. David Keefe Golan Hall Prof. Christophe Blockeel

6

Tuesday, May 19th, 2015 7:00 - con.

Registration, Refreshments & Exhibition Tour

8:00 - 9:30

Oral Presentations- Four Parallel Sessions

8:00 - 9:30

Hall A – Oral Presentation Session 5: Male Factor Chairs: Avi Ben-Haroush, Arieh Raziel, Yael Gonen, Mahmoud Huleihel

8:00

Sperm functions tests in infertile men with varicocele and normal fertile men Haim Pinkas1, Shoshani O.2, Stein A.1, Breitbart H.3 Male Infertility & Sperm Bank, Helen Schneider Hospital for, Women, Rabin Medical Center, 1 Beilinson Hospital, Petach Tikva, Sackler Faculty of Medicine, Tel-Aviv University , Department of Urology, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Sackler Faculty of Medicine, 2 3 Tel- Aviv University, Israel , Mina & Everard faculty of Life Science, Bar-Ilan University, Israel

8:12

Deleterious mutation in SYCE1 is associated with non-obstructive azoospermia Esther Maor-Sagie1, Cinnamon Y.2, Yaacov B.2, Shaag A.2, Goldsmidt H.3, Zenvirt S.2, Laufer N.1, Richler C.2, Frumkin A.2 Department of Obstetrics and Gynecology, Hadassah Ein-Karem, Hebrew University Medical 1 Center, Jerusalem, Israel , The Monique and Jacques Roboh Department of Genetic Research, 2 Hadassah, Hebrew University Medical Center, Jerusalem, Israel , Department of Pathology, 3 Hadassah, Hebrew University Medical Center, Jerusalem, Israel

8:24

Pentoxifylline in ART: use it or leave it? Dana Lapid, Milner E., Aharoni S., Wayner V., Hertz R., Kol S. IVF unit, Rambam Health Care Campus, Haifa, Israel

8:36

Pattern of expression of spermatogenic markers in testes of azoospermic men with non-mosaic Klinefelter syndrome Sandra E. Kleiman, Yogev L., Lehavi O., Paz G., Yavetz H., Hauser R. Institute for the Study of Fertility, Lis Maternity Hospital, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

8:48

Busulfan distinctly affected pre-meiotic cells in adult mice Ruth Levy1, Lunenfeld E.2, Huleihel M.1,3 The Shraga Segal Dep. of Microbiology, Immunology and Genetics, Faculty of Health Sciences, 1 Ben-Gurion University of the Negev, Beer Sheva , Dep. OB/GYN, Soroka Medical Center, The Center of Advanced Research and Education in Reproduction (CARER), and Faculty of Health 2 Sciences, Ben-Gurion University of the Negev, Beer Sheva , The Center of Advanced Research 3 and Education in Reproduction (CARER)

7

9:00

In vitro generation of spermatogonial differentating C-kit cells testicular cells of immature mice treated with busulfan; Possible involvement of testicular growth factors in this process Alina Stepanovsky1, Lunenfeld E.2, Huleihel M.1,3 The Shraga Segal Dep. of Microbiology, Immunology and Genetics, Faculty of Health Sciences, 1 Ben Gurion University of the Negev, Beer Sheva , Dep. OB/GYN, Soroka Medical Center, The Center of Advanced Research and Education in Reproduction (CARER), Faculty of Health 2 Sciences, Ben Gurion University of the Negev, Beer Sheva , The Center of Advanced Research 3 and Education in Reproduction (CARER)

9:12

Activated CaMKII prevents spontaneous acrosomal exocytosis via induction of actin polymerization Ortal Shabtay, Breitbart H. The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel

8:00 – 9:30 Hall B – Oral Presentation Session 6: ART Chairs: David Levran, Adrian Ellenbogen, Samer Khoury, Orit Radin 8:00

Oxidative markers in cryopreservation medium of frozen- thawed embryos in In Vitro Fertilization: A possible tool for improved embryo selection? Zofnat Wiener – Megnazi1, Lahav- Baratz S.1, Blais I.1, Matarasso S.1, Koifman M.1, Shnizer S.2, Younes G.1, Peer G.1, Auslander R.1, Dirnfeld M.1 Fertility and IVF Unit, Department of Obstetrics and Gynecology, Carmel Medical Center, the Bruce 1 2 Rappaport Faculty of Medicine, Technion, Haifa, Israel , Carmel Diagnostics. Ltd.

8:12

Co-administration of GnRH-agonist & hCG for final oocyte maturation in women with low number of oocytes retrieved per number of preovulatory follicles Eran Zilberberg, Orvieto R., Haas J., Dar S., Kedem A., Machtinger R. Chaim Sheba Medical Center, Tel-Hashomer, Israel

8:24

Egg donors eligibility according to the Israeli law of egg donation Raphael Ron-El, Ben-Ami I., Raziel A., Maslanski B., Gidoni Y.S., Bern O., Strassburger D., Komarovski D., Kasterstein E., Barover Z. IVF and Infertility Unit, Assaf Harofeh Medical Center, Tel-Aviv University, Israel

8:36

Mechanical stimulation of the endometrial lining to improve subsequent IVF cycle outcome: an analysis of 7 years of experience Dan Levin1, Cohen A.2, Barzilay L.2, Almog B.2

1

kaplan Medical Center, IVF Unit Department of Obstetrics and Gynecology, rehovot, Israel , 2 Sourasky Medical Center, Racine IVF Unit OB-GYN Devision, Tel-aviv, Israel

8

8:48

Late follicular Progesterone level (P) Progesterone/ Estradiol (P/E2) ratio is not influenced by different protocols or gonadotropins used Einat Shalom-Paz, Asalih N., Shavit T., Samara N., Yaakobi D., Michaeli M., Rotfarb N., Shoshan E., Shrem G., Ellenbogen A. Hillel Yafe Medical center, Hadera, Israel

9:00

Patient's decision of how many embryos to transfer is not entirely based on risk awareness of multiple pregnancies Emmanuel Attali, Ein Mor E., Haimov-Kochman R. IVF Unit, Hadassah Hebrew University Medical Center, Mt. Scopus, Jerusalem, Israel

9:12

The road to the last abdominal ultrasound use in IVF? Karavani Gilad1, Ben-Meir A.1, Hyman J.1, Shufaro Y.2, Revel A.1 Department of Obstetrics and Gynecology, Hadassah Hebrew University Hospital, Jerusalem, 1 Israel , Infertility and IVF Unit, Beilinson Women''s Hospital, Rabin Medical Center, Petach Tikva, 2 Israel

8:00- 9:30

Hall C – Oral Presentation Session 7: Stem Cells & PGD Chairs: Tal Imbar, Talia Eldar-Geva, Ariel Horowitz, Oshrat Schonberger

8:00

Polyglycine containing protein may play a role in pathogenesis of fragile X associated premature ovarian insufficiency in FMR1 premutation carriers Yoram Cohen, Dratviman-Storobinsky O., Aizer A., Dor J., Orvieto R., Elizur S. IVF Unit Chaim Sheba Medical Center, Tel-Hashomer, Israel

8:12

Impaired function of trophoblast cells derived from translocated hESCs may explain pregnancy loss Alina Shpiz1,2, Ben-Yosef D.1,2, Kalma Y.1 Wolfe PGD Stem Cell Lab, Racine IVF Unit, Lis Maternity Hospital, Tel-Aviv Sourasky Medical 1 Center, Israel , Dept. of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel-Aviv 2 University, Israel

8:24

Cost-effective and accurate single cell aneuploidy detection for PGS and translocation PGD using next generation sequencing David A. Zeevi1, Weinberg-Shukron A.1, Zeligson S.1, Beeri R.1, Dror T.1, Burak E.1, Ben Shlomo M.1, Hakam-Spektor E.1, Eldar-Geva T.2, Altarescu G.1

1

Medical Genetics Institute, ZOHAR PGD Unit, Shaare Zedek Medical Center, Jerusalem, Israel , Reproductive Endocrinology and Genetics Unit, Shaare Zedek Medical Center, Hebrew University, 2 Jerusalem, Israel

9

8:36

Cooperative "bank" for polymorphic markers covering most relevant genomic regions aimed to service PGD labs in Israel Mira Malcov, Peleg S., Frumkin T., Shpitz A., Malki L., Reches A., Ben-Yosef D., Amit A., Gold V. Racine IVF Unit, Lis Maternity Hospital, Tel-Aviv Sourasky Medical Center, Israel

8:48

Differentiation potential of naïve versus primed human embryonic stem cells Yael Kalma1, Petit I.2, Sarig O.2, Schwartz T.1, Cohen T.1, Amit A.1, Sprecher E.2, Ben-Yosef D.1,3 Wolfe PGD-Stem Cell lab and IVF lab, Racine IVF Unit, Tel-Aviv Sourasky Medical Center, 1 Tel-Aviv, Israel , Department of Dermatology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, 2 Israel , Department of Cell and Developmental Biology, Sackler School of medicine, Tel-Aviv 3 University, Tel-Aviv, Israel

9:00

Comparable results in warming cycles of embryos cryopreserved prior to or following embryo biopsy for PGD Onit Sapir, Kotler N., Shefer D., Biran G., Tomashov-Matar R., Krasilnikov N., Tzabari M., Margalit T., Shufaro Y., Fisch B., Garor R. Infertility and IVF Unit, Helen Schneider Hospital for Women & The Raphael Recanati Genetic Institute , Rabin Medical Center, Petach Tikva, and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

8:00 – 9:30 Golan Hall – Oral Presentation Session 8: Reproductive Biology Chairs: Joseph Lessing, Johnny Younis, Haim Breitbart, Zeev Shoham

8:00

FMR6 (a long non coding RNA) may play a role in the pathogenesis of fragile X associated premature ovarian insufficiency (FXPOI) Shai Elizur, Dratviman-Storobinsky O., Derech-Haim S., Lebovitz O., Dor J., Orvieto R., Cohen Y. IVF Unit Chaim Sheba Medical Center, Tel-Hashomer, Israel

8:12

The influence of in-vivo exposure to Nonylphenol Ethoxylate 10 (NP-10) on the ovarian reserve Yoel Shufaro1, Simaenov M.1, Saada A.2, Tsuberi B.3, Belaiche C.2, Kogot-Levin A.2, Shochat T.1, Fisch B.1, Abir R.1 Infertility and IVF Unit, Beilinson Women's Hospital, Rabin Medical Center, Petach Tikva; and the 1 Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel , Department of Genetic and 2 Metabolic Diseases, Hadassah-Hebrew University Medical Center, Jerusalem, Israel , Transgenic 3 Mice Unit, the Hebrew University Faculty of Medicine, Jerusalem, Israel

10

8:24

Uterine-expressed FOXL2 regulates genes expression involved in uterus receptivity and embryo implantation Michal Elbaz1, Hadas R.2, Bilezikjian L. M.3, Gershon E.1,

1

Department of Ruminant Science, Agricultural Research Organization, Bet Dagan, Israel , 2 Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel , Clayton Foundation Laboratories for Peptide Biology and Laboratory of Neuronal Structure and Function, 3 Salk Institute for Biological Studies, La Jolla, CA, USA

8:36

Reduced granulosa cells mitochondrial activity with aging is a co-enzyme Q dependent Assaf Ben-Meir1, Yahalomi S.1, Brit M.2, Shufaro Y.1, Reubinoff B.1, Saada-Reisch A.2

1

Obstetrics & Gynecology dept., Hadassah-Hebrew University Medical Center, Jerusalem, Israel , 2 Department of Genetic and Metabolic Diseases, Hadassah-Hebrew University Medical Center

8:48

The angiogenic role of hyaluronic acid during embryo implantation Ron Hadas1, Gershon E.2, Cohen A.1, Dekel N.1, Neeman M.1 1

The Weizmann Institute of Science, Rehovot, Israel , Agricultural Research Organization, 2 Volcani Center, Bet-Dagan, Israel

9:00

Epigenetic control of postpartum behavior: Lack of the chromatin protein HP1BP3 associates with impaired maternal care and reduced offspring survival Benjamin Garfinkel1, Arad S.2, Gal M.2,3, Orly J.1 Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The 1 Hebrew University of Jerusalem, Jerusalem, Israel , Biomedical Sciences, The Faculty of 2 Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel , The IVF Unit-Ob/Gyn Dept., 3 Shaare Zedek Medical Center, Jerusalem, Israel

9:12

MiR-125a-3p inhibits GVBD of mouse oocytes through modulation of Fyn expression Hadas Grossman1, Har-Paz E.1, Levi M.1, Nevo N.2, Galiani D.2, Dekel N.2, Shalgi R.1 1

Tel-Aviv University, Tel-Aviv, Israel , The Weizmann Institute of Science, Rehovot, Israel

9:30-10:00

Exhibition & Refreshments

11

2

10:00 -11:40 Hall A Plenary Session 3 Invited Speakers Chairs: Rami (Jeremy) Don, Genia Ziskind 10:00

Inhibition of retinoic acid receptors as a novel approach to male contraception Prof. Debra J. Wolgemuth Professor of Genetics and Development and Obstetrics and Gynecology Institute of Human Nutrition. Herbert Irving Comprehensive Cancer Center Columbia University Medical Center, New York, USA

10:50

Natural selection of human embryos at implantation Prof. Jan Brosens Division OF reproductive HEALTH. Warwick Medical School, Clinical Sciences research Laboratories, University Hospital, UK

00:00-05:30 Galil Hall – Session 4: Psychosocial Separate Program

‫סוציאלי‬-‫מושב פסיכו‬ ‫תוכנית בנפרד‬

11:40- 12:10 Exhibition & Refreshments

12:10- 14:30 Hall A Plenary Session 4 Chairs: Benjamin Reubinoff, Alex Tsafriri 12:10

In vitro reconstruction of primordial germ cell lineage from human pluripotent cells Dr. Jacob Hanna Department of Molecular Genetics Azrieli Institute for Systems Biology, Chromatin & RNA Gene Regulation i-Core Weizmann Institute of Science, Israel

12:50

Recorded lecture In Vitro Activation of ovarian follicles: From bench to clinic Dr. Aaron J. W. Hsueh Division of Reproductive and Stem Cell Biology. Department of Obstetrics and Gynecology, Stanford University, School of Medicine, Palo Alto, USA

12

13:20-14:15 Award Papers Presentations & Awards Chair: Dror Meirow 13:20

GnRH agonist modulates PEDF/VEGF ratio inversely to hCG in granulosa cells Irit Miller1, Chuderland D.1, Ron-El R.2, Shalgi R.1, Ben-Ami I.2 Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel-Aviv University, 1 Tel-Aviv, Israel , IVF and Infertility Unit, Department of Obstetrics and Gynecology, Assaf Harofeh 2 Medical Center, Zerifin and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

13:35

miRNAs as new regulators of the ovulatory cascade-Characterization of the human ovulatory non-coding transcriptome Libby Ophir1, Yerushalmi G. M.1, Yung Y.1, Maman E.1, Baum M.1, Salmon-Divon M.2, Ourvieto R.1, Hourvitz A.1 Reproduction Lab and IVF Unit, Department of Obstetrics and Gynecology, Sheba Medical Center, 1 Tel Hashomer, Affiliated with the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel , 2 Department of Molecular Biology, Ariel University, Ariel, Israel

13:50

PEDF regulation by hCG in granulosa cells Hadas Bar-Joseph, Ben-Ami I., Ron-El R., Shalgi R., Chuderland D. Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel-Aviv University, 1 Tel-Aviv, Israel , IVF and Infertility Unit, Department of Obstetrics and Gynecology, Assaf Harofeh 2 Medical Center, Zerifin Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

14:05

- ‫הענקת פרסים‬ ‫ מחקרי‬3‫ קליני ו‬3 ‫ ששה פרסים יוענקו לעבודות מצטיינות‬,‫שני פרסים יוענקו לפוסטרים מצטיינים‬ ‫שני עבודות הפרס המצטיינות בתחום הקליני ובתחום המחקרי ע״ש פרופ' שלמה משיח‬ :‫ועדות פרס‬ ‫ מרתה דירנפלד‬,‫ אילן קלדרון‬,‫ נתן לויט‬,‫ שבח פרידלר‬- ‫ יו"ר‬:‫פרס קליני‬ ‫ נאוה דקל‬,‫ חננאל הולצר‬,‫ יוסי אורלי‬,‫ דרור מאירוב‬- ‫ יו"ר‬:‫פרס מחקרי‬ ‫ בני אלמוג‬,‫ שחר קול‬,‫ אדריאן שולמן‬,‫ שי אליצור‬- ‫ יו"ר‬:‫פרס פוסטר‬

14:15-14:30 General Assembly

14:30 -15:30 Lunch

16:00-17:00 Round Table Discussion Galil Hall Golan Hall

Prof. Debra J. Wolgemuth Prof. Jan Brosens

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