Course Directors

Igal Kam, MD, University of Colorado Gregory T. Everson, MD, University of Colorado Laurence Chan, MD, PhD, University of Colorado

University of Colorado Faculty Tom Bak, MD Kiran Bambha, MD Scott Biggins, MD James Burton, MD James Cooper, MD

Lisa Forman, MD Alkesh Jani, MD Frederick Karrer, MD Hugo Rosen, MD Michael Wachs, MD

Alex Wiseman, MD Michael Zimmerman, MD Nursing Coordinator

University of Colorado School of Medicine Division of Transplant Surgery Mail Stop C318 1635 Aurora Court Aurora, CO 80045

Tracy Steinberg, RN, MS

Sponsored by: University of Colorado School of Medicine Office of Continuing Medical Education

Guest Faculty Robert Brown, MD

Chief, Division of Abdominal and Organ Transplantation Columbia Presbyterian Medical Center New York, New York

Michael Charlton, MD

Medical Director, Liver Transplantation Mayo Clinic Rochester, Minnesota

Gabriel Danovitch, MD

Medical Director, Kidney and Pancreas Transplant University of California, Los Angeles Los Angeles, California

Sue Dunn, RN, BSN, MBA, CTTC President and CEO of Donor Alliance Organ Procurement Organization Denver, Colorado

Jean Emond, MD

Vice Chair and Director of Transplantation Columbia Presbyterian Medical Center New York, New York

Sheung Tat Fan, MD

Chairman, Department of Surgery and Head of Hepatobiliary & Pancreatic

Surgery and Liver Transplantation University of Hong Kong Hong Kong, China

John Fung, MD

Chairman, General Surgery and Director of Transplant Center Cleveland Clinic Foundation Cleveland, Ohio

John Lake, MD

Medical Director, Liver Transplantation Director, Gastroenterology University of Minnesota Minneapolis, Minnesota

Deepak Malhotra, MD

Transplant Nephrologist University of Toledo Medical Center Toledo, Ohio

Charles Miller, MD

Director, Liver Transplantation Program Cleveland Clinic Foundation Cleveland Ohio

Kim Olthoff, MD

Director, Liver Transplant Program University of Pennsylvania Hospital Philadelphia, Pennsylvania

Elizabeth Pomfret, MD, PhD Director, Adult Live Donor Liver Transplantation Lahey Clinic Medical Center Burlington, Massachusetts

University of Pennsylvania Hospital Philadelphia, Pennsylvania

Roshan Shrestha, MD

Lloyd Ratner, MD

Medical Director, Liver Transplantation Piedmont Hospital Atlanta, Georgia

K. Rajender Reddy, MD

Director, MacLean Center for Clinical Medical Ethics University of Chicago Chicago, Illinois

Michael Rees, MD

Surgical Director, Pediatric Renal and Adult Pancreas Transplant Program UCSF Medical Center San Francisco, California

Director, Renal & Pancreatic Transplant Columbia University Medical Center New York, New York Medical Director, Liver Transplantation Hospital of the University of Pennsylvania Philadelphia, Pennsylvania Director, Renal Transplantation University of Toledo Medical Center Toledo, Ohio

Marty Sellers, MD

Director, Piedmont Liver Cancer Piedmont Transplant Institute Atlanta, Georgia

Abraham Shaked, MD, PhD Chief, Division of Transplantation Surgery

Presented by: The Division of Transplant Surgery, Department of Surgery The Division of Renal Diseases and Section of Hepatology, Department of Medicine University of Colorado School of Medicine and the University of Colorado Hospital

Young Investigator’s Forum •March 3, 2011

Mark Siegler, MD

Peter Stock, MD

James Trotter, MD

Medical Director of Liver Transplant Baylor University Medical Center Dallas, Texas

Course OBJECTIVES/General Information

Target Audience: This program is designed for healthcare professionals who provide patient care at all levels in transplantation. The course is designed for, but not limited to, surgeons, hepatologists, nephrologists, nurses, social workers and pharmacists. Statement of Need/Program Overview: The University of Colorado faculty and guest speakers will address topics on live donor transplantation, immunosuppression and whom to transplant, sickest versus the fittest. Other topics will include hepatitis and updates with organ procurement organizations. Learning Objectives: At the conclusion of this conference, participants should be able to:

CONTROVERSIES IN

TRANSPLANTATION March 4-6, 2011

Young Investigator’s Forum March 3, 2011

Beaver Run Conference Center • Breckenridge, CO

Russell Wiesner, MD

Medical Director, Clinical Trial Services Mayo Clinic Rochester, Minnesota



This program is part of the Colorado Statewide Extended Campus. State funds were not used to develop or administer this program.

■ Analyze donor safety in living donor liver transplantation.

Friday-Sunday, March 4-6, 2011

Beaver Run Conference Center • Breckenridge, CO

CONTROVERSIES IN

TRANSPLANTATION

■ C  ompare outcomes of live donor liver transplantation with deceased donor liver transplantation. ■ I dentify ethical issues requiring management by teams performing live donor transplantation. ■ A  ssess the disease severity and mortality of patients using the Model for End-Stage Liver Disease (MELD). ■ Define the reshaping of organ procurement organizations (OPO). ■ Assess current challenges in kidney transplant.

ACCREDITATION Accreditation Statement: The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The University of Colorado School of Medicine designates this educational activity for a maximum of 16 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity. CEU and CEPTC credits have been applied for through the International Transplant Nurses Society

Course Directors

Igal Kam, MD, University of Colorado Gregory T. Everson, MD, University of Colorado Laurence Chan, MD, PhD, University of Colorado

University of Colorado Faculty Tom Bak, MD Kiran Bambha, MD Scott Biggins, MD James Burton, MD James Cooper, MD

Lisa Forman, MD Alkesh Jani, MD Frederick Karrer, MD Hugo Rosen, MD Michael Wachs, MD

Alex Wiseman, MD Michael Zimmerman, MD Nursing Coordinator

University of Colorado School of Medicine Division of Transplant Surgery Mail Stop C318 1635 Aurora Court Aurora, CO 80045

Tracy Steinberg, RN, MS

Sponsored by: University of Colorado School of Medicine Office of Continuing Medical Education

Guest Faculty Robert Brown, MD

Chief, Division of Abdominal and Organ Transplantation Columbia Presbyterian Medical Center New York, New York

Michael Charlton, MD

Medical Director, Liver Transplantation Mayo Clinic Rochester, Minnesota

Gabriel Danovitch, MD

Medical Director, Kidney and Pancreas Transplant University of California, Los Angeles Los Angeles, California

Sue Dunn, RN, BSN, MBA, CTTC President and CEO of Donor Alliance Organ Procurement Organization Denver, Colorado

Jean Emond, MD

Vice Chair and Director of Transplantation Columbia Presbyterian Medical Center New York, New York

Sheung Tat Fan, MD

Chairman, Department of Surgery and Head of Hepatobiliary & Pancreatic

Surgery and Liver Transplantation University of Hong Kong Hong Kong, China

John Fung, MD

Chairman, General Surgery and Director of Transplant Center Cleveland Clinic Foundation Cleveland, Ohio

John Lake, MD

Medical Director, Liver Transplantation Director, Gastroenterology University of Minnesota Minneapolis, Minnesota

Deepak Malhotra, MD

Transplant Nephrologist University of Toledo Medical Center Toledo, Ohio

Charles Miller, MD

Director, Liver Transplantation Program Cleveland Clinic Foundation Cleveland Ohio

Kim Olthoff, MD

Director, Liver Transplant Program University of Pennsylvania Hospital Philadelphia, Pennsylvania

Elizabeth Pomfret, MD, PhD Director, Adult Live Donor Liver Transplantation Lahey Clinic Medical Center Burlington, Massachusetts

University of Pennsylvania Hospital Philadelphia, Pennsylvania

Roshan Shrestha, MD

Lloyd Ratner, MD

Medical Director, Liver Transplantation Piedmont Hospital Atlanta, Georgia

K. Rajender Reddy, MD

Director, MacLean Center for Clinical Medical Ethics University of Chicago Chicago, Illinois

Michael Rees, MD

Surgical Director, Pediatric Renal and Adult Pancreas Transplant Program UCSF Medical Center San Francisco, California

Director, Renal & Pancreatic Transplant Columbia University Medical Center New York, New York Medical Director, Liver Transplantation Hospital of the University of Pennsylvania Philadelphia, Pennsylvania Director, Renal Transplantation University of Toledo Medical Center Toledo, Ohio

Marty Sellers, MD

Director, Piedmont Liver Cancer Piedmont Transplant Institute Atlanta, Georgia

Abraham Shaked, MD, PhD Chief, Division of Transplantation Surgery

Presented by: The Division of Transplant Surgery, Department of Surgery The Division of Renal Diseases and Section of Hepatology, Department of Medicine University of Colorado School of Medicine and the University of Colorado Hospital

Young Investigator’s Forum •March 3, 2011

Mark Siegler, MD

Peter Stock, MD

James Trotter, MD

Medical Director of Liver Transplant Baylor University Medical Center Dallas, Texas

Course OBJECTIVES/General Information

Target Audience: This program is designed for healthcare professionals who provide patient care at all levels in transplantation. The course is designed for, but not limited to, surgeons, hepatologists, nephrologists, nurses, social workers and pharmacists. Statement of Need/Program Overview: The University of Colorado faculty and guest speakers will address topics on live donor transplantation, immunosuppression and whom to transplant, sickest versus the fittest. Other topics will include hepatitis and updates with organ procurement organizations. Learning Objectives: At the conclusion of this conference, participants should be able to:

CONTROVERSIES IN

TRANSPLANTATION March 4-6, 2011

Young Investigator’s Forum March 3, 2011

Beaver Run Conference Center • Breckenridge, CO

Russell Wiesner, MD

Medical Director, Clinical Trial Services Mayo Clinic Rochester, Minnesota



This program is part of the Colorado Statewide Extended Campus. State funds were not used to develop or administer this program.

■ Analyze donor safety in living donor liver transplantation.

Friday-Sunday, March 4-6, 2011

Beaver Run Conference Center • Breckenridge, CO

CONTROVERSIES IN

TRANSPLANTATION

■ C  ompare outcomes of live donor liver transplantation with deceased donor liver transplantation. ■ I dentify ethical issues requiring management by teams performing live donor transplantation. ■ A  ssess the disease severity and mortality of patients using the Model for End-Stage Liver Disease (MELD). ■ Define the reshaping of organ procurement organizations (OPO). ■ Assess current challenges in kidney transplant.

ACCREDITATION Accreditation Statement: The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The University of Colorado School of Medicine designates this educational activity for a maximum of 16 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity. CEU and CEPTC credits have been applied for through the International Transplant Nurses Society

Friday Morning

MARCH 4TH 7:00 am 7:30 am 9:20 am 10:00 am

Breakfast/Registration Michael Rees Lloyd Ratner Gabriel Danovitch TBA Session Discussion/Debate Adjourn

Friday Afternoon

3:00 pm Apres Ski Refreshments 3:30 pm Elizabeth Pomfret Igal Kam Sheung Tat Fan Charlie Miller Mark Siegler 6:00 pm Session Discussion/Debate 7:00 pm Adjourn

New challenges in renal transplant

Moderators: Larry Chan and Alex Wiseman

What is new in paired exchange Expanded criteria for diseased donors – ECD/DCD The promotion of living kidney donation in the USA To pump or not to pump

Donor safety in transplantation

Moderators: Kiran Bambha and Jack Lake Donor death in Boston Donor death in Colorado Donor complications in Hong Kong Left lobe vs. right lobe Ethical issues living donation

Friday Evening Current and Future Treatments for HBV and HCV Dinner Program Moderators: Greg Everson and Rajender Reddy 7:00 pm Robert Brown K. Rajender Reddy

Nucleos(t)ides for HBV Direct acting antivirals for HCV

FACILITIES AND SURROUNDINGS

MARCH 5 7:00 am 7:30 am 9:20 am 10:00 am

Just an hour and one-half drive from Denver is the quaint, historic town of Breckenridge. Beaver Run Conference Center is nestled at the base of Peak 9, the largest conference center in the Rockies under one roof. This ski in/ski out resort can put you onto more than 126 ski trails. A free shuttle service can take you to other nearby resorts: Keystone, Copper Mountain and Arapahoe Basin. Other winter activities include ice skating, snowmobiling, sleigh rides and helicopter skiing, just to name a few. After a day of meetings, you can relax in one of Beaver Run’s two heated pools, seven hot tubs, or experience the many fine restaurants and shopping.

Breakfast Peter Stock Transplant in the patient with HIV Michael Charlton IL28b polymorphism and liver allocation John Fung Advances in immunosuppression Sue Dunn Changes in OPO’s John Lake UNOS and the transplant center Session Discussion/Debate Adjourn

Saturday Afternoon

3:00 pm Apres Ski Refreshments 3:30 pm Russ Weisner James Trotter Avi Shaked Kim Olthoff Jean Emond 6:30 pm Session Discussion/Debate 7:00 pm Adjourn 7:30 pm Dinner

Beyond MELD: Who should NOT be transplanted??

Moderators: Hugo Rosen and Scott Biggins

Development and validation of MELD Pitfalls of the MELD Score Realities of transplanting high MELD patients Transplant the fittest: outcome driven Alternatives to MELD

COLORADO MOUNTAIN EXPRESS Sunday Morning Case Presentations Moderators: Roshan Shrestha and Tracy Steinberg

MARCH 6TH 7:00 am 7:30 am 10:00 pm 10:30 pm

Breakfast Case Presentations Marty Sellers Deepak Malhotra Avi Shaked James Cooper Session discussion/debate Adjourn

Colorado Mountain Express shuttle service will offer a discounted rate of $142.60 round trip fare (or $71.10 one way), to meeting participants, from DIA to Beaver Run Resort. Call 1-800-334-7433 and use group code CIT.

Social Event All registrants and their families are invited to a dinner on Saturday, March 5th, 7:00 pm. Dinner, beer, wine and soft drinks will be provided. A block of rooms will be held at Beaver Run Conference Center until January 17, 2011. After that date, rooms will be on a space available basis only. This is peak ski season. BOOK EARLY!

FEES Early registration - postmarked before February 1, 2011 $400 Late registration - postmarked after February 1, 2011 $450 Registration to the Controversies in Transplantation includes the Hepatology Young Investigators Forum. Make check payable to the Division of Transplant Surgery. An 80% refund will be made for cancellations prior to February 1, 2011. No refunds will be made for cancellations after this time or for nonattendance. A comprehensive course syllabus containing outlines and abstracts of the presentations will be given to each registrant. Mail conference registration form and check to: Jody Mandic University of Colorado Division of Transplant Surgery Mail Stop C318 1635 Aurora Court, Aurora, CO 80045 Tel: 720-848-0833 Fax: 720-848-0841 Email: [email protected] Online Registration Register on-line at: http://www.medschool.ucdenver.edu/CME Click on the Register Now button. Payment by Visa or MasterCard is required to register on-line. When you register on-line, you will receive immediate confirmation of your conference registration.

HOTELReservation RESERVATIONForm FORM Hotel

CONFERENCE REGISTRATION FORM

GROUP NAME: Transplant, FOR RESERVATIONS CALL: 1-800-525-2253; in Colorado Register on-line at: http://www.medschool.ucdenver.edu/CME call (970)453-6000 OR MAIL THIS TOP FORM TO: Beaver Run Reservations, P.O. Box 2115, Breckenridge, CO 80424. Last Name______________________________ First Name ____________________________ ACCOMMODATIONS: Please indicate your first and second choices below. Use this (state name as you’d like it to appear on your CME certificate) form for one room only. Other units available upon request. For views, descriptions of ☐ MD ☐ PhD ☐ DO ☐ RN ☐ PA ☐ PharmD rooms and to book your room go to: www.beaverrun.com Type Rate Persons Type Rate Persons Affiliation_____________________________ Address Hotel Room $227 2-4 1 Bedroom Premium $409 2-4 City___________________________________ State____________ Zip Deluxe Studio w/spa $270 2-4 2 Bedroom/2 Bath $535 4-6 Colorado Suite w/spa $342 2-4 2 Bedroom Premium $626 4-6 Home Phone____________________________ Business Phone One Bdrm Condo $342 2-4 E-Mail (please print clearly) NOTE: Above rates do not include state or local taxes; may not exceed maximum occupancy. Children 14 or under stay free in same room as parents. Check-in time is 4:00 p.m., check-out time is 11:00 a.m. No pets in rooms.

(We will not provide your email address to anyone outside the CME office or Div of TS.)

Dates of attendance: ☐ Thursday YIF ☐ Friday ☐ Friday dinner program (meeting attendees only) Name ☐ Saturday ☐ Sunday

Address Early registration (postmarked before February 1, 2011) $400 Late registration (postmarked after February 1, 2011) $450 City State Zip Saturday night dinner - number of adults including registrant ____ number of children ____ Home Phone Business Phone MC #_____________________ Exp____ Visa #_____________________ Exp______ List of all roommates

If you have a disability and require accommodations in order to fully participate in this activity,

check here.☐ You will be contacted by someone from the planning committee to discuss your specific needs. Arrival Date Departure Date

Please make registration check payable to Division of Transplant Surgery

Deposit/Cancellation Policy: Deposit of 2 nights per unit is required to confirm reservation. Remaining balance including 13.9% tax is required 30 days prior to arrival. Deposit will be refunded, less $75 handling charge per room, if cancellation is received prior to 30 days of scheduled arrival. If cancellation is received less than 30 days prior to arrival date, all monies will be forfeited. Reservations received after January 17, 2011 will be on a space available basis. There is a three-night lodging minimum.

Enclosed is a check or money order for $

, or I authorize deposit amount of

$ to be charged to my credit card. ☐ VISA

☐ MASTERCARD

Credit Card # Exp Printed Name

Signature

Mail conference registration form and check to:

Cut Here ✄

SCIENTIFIC PROGRAM

Saturday Morning Emerging issues in Transplantation Moderators: Lisa Forman and Abraham Shaked TH

Jody Mandic University of Colorado Anschutz Medical Campus Division of Transplant Surgery MS C318 1635 Aurora Court Aurora, CO 80045

Tel: 720-848-0852 • Fax 720-848-0841 Email: [email protected]­­

Friday Morning

MARCH 4TH 7:00 am 7:30 am 9:20 am 10:00 am

Breakfast/Registration Michael Rees Lloyd Ratner Gabriel Danovitch TBA Session Discussion/Debate Adjourn

Friday Afternoon

3:00 pm Apres Ski Refreshments 3:30 pm Elizabeth Pomfret Igal Kam Sheung Tat Fan Charlie Miller Mark Siegler 6:00 pm Session Discussion/Debate 7:00 pm Adjourn

New challenges in renal transplant

Moderators: Larry Chan and Alex Wiseman

What is new in paired exchange Expanded criteria for diseased donors – ECD/DCD The promotion of living kidney donation in the USA To pump or not to pump

Donor safety in transplantation

Moderators: Kiran Bambha and Jack Lake Donor death in Boston Donor death in Colorado Donor complications in Hong Kong Left lobe vs. right lobe Ethical issues living donation

Friday Evening Current and Future Treatments for HBV and HCV Dinner Program Moderators: Greg Everson and Rajender Reddy 7:00 pm Robert Brown K. Rajender Reddy

Nucleos(t)ides for HBV Direct acting antivirals for HCV

FACILITIES AND SURROUNDINGS

MARCH 5 7:00 am 7:30 am 9:20 am 10:00 am

Just an hour and one-half drive from Denver is the quaint, historic town of Breckenridge. Beaver Run Conference Center is nestled at the base of Peak 9, the largest conference center in the Rockies under one roof. This ski in/ski out resort can put you onto more than 126 ski trails. A free shuttle service can take you to other nearby resorts: Keystone, Copper Mountain and Arapahoe Basin. Other winter activities include ice skating, snowmobiling, sleigh rides and helicopter skiing, just to name a few. After a day of meetings, you can relax in one of Beaver Run’s two heated pools, seven hot tubs, or experience the many fine restaurants and shopping.

Breakfast Peter Stock Transplant in the patient with HIV Michael Charlton IL28b polymorphism and liver allocation John Fung Advances in immunosuppression Sue Dunn Changes in OPO’s John Lake UNOS and the transplant center Session Discussion/Debate Adjourn

Saturday Afternoon

3:00 pm Apres Ski Refreshments 3:30 pm Russ Weisner James Trotter Avi Shaked Kim Olthoff Jean Emond 6:30 pm Session Discussion/Debate 7:00 pm Adjourn 7:30 pm Dinner

Beyond MELD: Who should NOT be transplanted??

Moderators: Hugo Rosen and Scott Biggins

Development and validation of MELD Pitfalls of the MELD Score Realities of transplanting high MELD patients Transplant the fittest: outcome driven Alternatives to MELD

COLORADO MOUNTAIN EXPRESS Sunday Morning Case Presentations Moderators: Roshan Shrestha and Tracy Steinberg

MARCH 6TH 7:00 am 7:30 am 10:00 pm 10:30 pm

Breakfast Case Presentations Marty Sellers Deepak Malhotra Avi Shaked James Cooper Session discussion/debate Adjourn

Colorado Mountain Express shuttle service will offer a discounted rate of $142.60 round trip fare (or $71.10 one way), to meeting participants, from DIA to Beaver Run Resort. Call 1-800-334-7433 and use group code CIT.

Social Event All registrants and their families are invited to a dinner on Saturday, March 5th, 7:00 pm. Dinner, beer, wine and soft drinks will be provided. A block of rooms will be held at Beaver Run Conference Center until January 17, 2011. After that date, rooms will be on a space available basis only. This is peak ski season. BOOK EARLY!

FEES Early registration - postmarked before February 1, 2011 $400 Late registration - postmarked after February 1, 2011 $450 Registration to the Controversies in Transplantation includes the Hepatology Young Investigators Forum. Make check payable to the Division of Transplant Surgery. An 80% refund will be made for cancellations prior to February 1, 2011. No refunds will be made for cancellations after this time or for nonattendance. A comprehensive course syllabus containing outlines and abstracts of the presentations will be given to each registrant. Mail conference registration form and check to: Jody Mandic University of Colorado Division of Transplant Surgery Mail Stop C318 1635 Aurora Court, Aurora, CO 80045 Tel: 720-848-0833 Fax: 720-848-0841 Email: [email protected] Online Registration Register on-line at: http://www.medschool.ucdenver.edu/CME Click on the Register Now button. Payment by Visa or MasterCard is required to register on-line. When you register on-line, you will receive immediate confirmation of your conference registration.

HOTELReservation RESERVATIONForm FORM Hotel

CONFERENCE REGISTRATION FORM

GROUP NAME: Transplant, FOR RESERVATIONS CALL: 1-800-525-2253; in Colorado Register on-line at: http://www.medschool.ucdenver.edu/CME call (970)453-6000 OR MAIL THIS TOP FORM TO: Beaver Run Reservations, P.O. Box 2115, Breckenridge, CO 80424. Last Name______________________________ First Name ____________________________ ACCOMMODATIONS: Please indicate your first and second choices below. Use this (state name as you’d like it to appear on your CME certificate) form for one room only. Other units available upon request. For views, descriptions of ☐ MD ☐ PhD ☐ DO ☐ RN ☐ PA ☐ PharmD rooms and to book your room go to: www.beaverrun.com Type Rate Persons Type Rate Persons Affiliation_____________________________ Address Hotel Room $227 2-4 1 Bedroom Premium $409 2-4 City___________________________________ State____________ Zip Deluxe Studio w/spa $270 2-4 2 Bedroom/2 Bath $535 4-6 Colorado Suite w/spa $342 2-4 2 Bedroom Premium $626 4-6 Home Phone____________________________ Business Phone One Bdrm Condo $342 2-4 E-Mail (please print clearly) NOTE: Above rates do not include state or local taxes; may not exceed maximum occupancy. Children 14 or under stay free in same room as parents. Check-in time is 4:00 p.m., check-out time is 11:00 a.m. No pets in rooms.

(We will not provide your email address to anyone outside the CME office or Div of TS.)

Dates of attendance: ☐ Thursday YIF ☐ Friday ☐ Friday dinner program (meeting attendees only) Name ☐ Saturday ☐ Sunday

Address Early registration (postmarked before February 1, 2011) $400 Late registration (postmarked after February 1, 2011) $450 City State Zip Saturday night dinner - number of adults including registrant ____ number of children ____ Home Phone Business Phone MC #_____________________ Exp____ Visa #_____________________ Exp______ List of all roommates

If you have a disability and require accommodations in order to fully participate in this activity,

check here.☐ You will be contacted by someone from the planning committee to discuss your specific needs. Arrival Date Departure Date

Please make registration check payable to Division of Transplant Surgery

Deposit/Cancellation Policy: Deposit of 2 nights per unit is required to confirm reservation. Remaining balance including 13.9% tax is required 30 days prior to arrival. Deposit will be refunded, less $75 handling charge per room, if cancellation is received prior to 30 days of scheduled arrival. If cancellation is received less than 30 days prior to arrival date, all monies will be forfeited. Reservations received after January 17, 2011 will be on a space available basis. There is a three-night lodging minimum.

Enclosed is a check or money order for $

, or I authorize deposit amount of

$ to be charged to my credit card. ☐ VISA

☐ MASTERCARD

Credit Card # Exp Printed Name

Signature

Mail conference registration form and check to:

Cut Here ✄

SCIENTIFIC PROGRAM

Saturday Morning Emerging issues in Transplantation Moderators: Lisa Forman and Abraham Shaked TH

Jody Mandic University of Colorado Anschutz Medical Campus Division of Transplant Surgery MS C318 1635 Aurora Court Aurora, CO 80045

Tel: 720-848-0852 • Fax 720-848-0841 Email: [email protected]­­

Friday Morning

MARCH 4TH 7:00 am 7:30 am 9:20 am 10:00 am

Breakfast/Registration Michael Rees Lloyd Ratner Gabriel Danovitch TBA Session Discussion/Debate Adjourn

Friday Afternoon

3:00 pm Apres Ski Refreshments 3:30 pm Elizabeth Pomfret Igal Kam Sheung Tat Fan Charlie Miller Mark Siegler 6:00 pm Session Discussion/Debate 7:00 pm Adjourn

New challenges in renal transplant

Moderators: Larry Chan and Alex Wiseman

What is new in paired exchange Expanded criteria for diseased donors – ECD/DCD The promotion of living kidney donation in the USA To pump or not to pump

Donor safety in transplantation

Moderators: Kiran Bambha and Jack Lake Donor death in Boston Donor death in Colorado Donor complications in Hong Kong Left lobe vs. right lobe Ethical issues living donation

Friday Evening Current and Future Treatments for HBV and HCV Dinner Program Moderators: Greg Everson and Rajender Reddy 7:00 pm Robert Brown K. Rajender Reddy

Nucleos(t)ides for HBV Direct acting antivirals for HCV

FACILITIES AND SURROUNDINGS

MARCH 5 7:00 am 7:30 am 9:20 am 10:00 am

Just an hour and one-half drive from Denver is the quaint, historic town of Breckenridge. Beaver Run Conference Center is nestled at the base of Peak 9, the largest conference center in the Rockies under one roof. This ski in/ski out resort can put you onto more than 126 ski trails. A free shuttle service can take you to other nearby resorts: Keystone, Copper Mountain and Arapahoe Basin. Other winter activities include ice skating, snowmobiling, sleigh rides and helicopter skiing, just to name a few. After a day of meetings, you can relax in one of Beaver Run’s two heated pools, seven hot tubs, or experience the many fine restaurants and shopping.

Breakfast Peter Stock Transplant in the patient with HIV Michael Charlton IL28b polymorphism and liver allocation John Fung Advances in immunosuppression Sue Dunn Changes in OPO’s John Lake UNOS and the transplant center Session Discussion/Debate Adjourn

Saturday Afternoon

3:00 pm Apres Ski Refreshments 3:30 pm Russ Weisner James Trotter Avi Shaked Kim Olthoff Jean Emond 6:30 pm Session Discussion/Debate 7:00 pm Adjourn 7:30 pm Dinner

Beyond MELD: Who should NOT be transplanted??

Moderators: Hugo Rosen and Scott Biggins

Development and validation of MELD Pitfalls of the MELD Score Realities of transplanting high MELD patients Transplant the fittest: outcome driven Alternatives to MELD

COLORADO MOUNTAIN EXPRESS Sunday Morning Case Presentations Moderators: Roshan Shrestha and Tracy Steinberg

MARCH 6TH 7:00 am 7:30 am 10:00 pm 10:30 pm

Breakfast Case Presentations Marty Sellers Deepak Malhotra Avi Shaked James Cooper Session discussion/debate Adjourn

Colorado Mountain Express shuttle service will offer a discounted rate of $142.60 round trip fare (or $71.10 one way), to meeting participants, from DIA to Beaver Run Resort. Call 1-800-334-7433 and use group code CIT.

Social Event All registrants and their families are invited to a dinner on Saturday, March 5th, 7:00 pm. Dinner, beer, wine and soft drinks will be provided. A block of rooms will be held at Beaver Run Conference Center until January 17, 2011. After that date, rooms will be on a space available basis only. This is peak ski season. BOOK EARLY!

FEES Early registration - postmarked before February 1, 2011 $400 Late registration - postmarked after February 1, 2011 $450 Registration to the Controversies in Transplantation includes the Hepatology Young Investigators Forum. Make check payable to the Division of Transplant Surgery. An 80% refund will be made for cancellations prior to February 1, 2011. No refunds will be made for cancellations after this time or for nonattendance. A comprehensive course syllabus containing outlines and abstracts of the presentations will be given to each registrant. Mail conference registration form and check to: Jody Mandic University of Colorado Division of Transplant Surgery Mail Stop C318 1635 Aurora Court, Aurora, CO 80045 Tel: 720-848-0833 Fax: 720-848-0841 Email: [email protected] Online Registration Register on-line at: http://www.medschool.ucdenver.edu/CME Click on the Register Now button. Payment by Visa or MasterCard is required to register on-line. When you register on-line, you will receive immediate confirmation of your conference registration.

HOTELReservation RESERVATIONForm FORM Hotel

CONFERENCE REGISTRATION FORM

GROUP NAME: Transplant, FOR RESERVATIONS CALL: 1-800-525-2253; in Colorado Register on-line at: http://www.medschool.ucdenver.edu/CME call (970)453-6000 OR MAIL THIS TOP FORM TO: Beaver Run Reservations, P.O. Box 2115, Breckenridge, CO 80424. Last Name______________________________ First Name ____________________________ ACCOMMODATIONS: Please indicate your first and second choices below. Use this (state name as you’d like it to appear on your CME certificate) form for one room only. Other units available upon request. For views, descriptions of ☐ MD ☐ PhD ☐ DO ☐ RN ☐ PA ☐ PharmD rooms and to book your room go to: www.beaverrun.com Type Rate Persons Type Rate Persons Affiliation_____________________________ Address Hotel Room $227 2-4 1 Bedroom Premium $409 2-4 City___________________________________ State____________ Zip Deluxe Studio w/spa $270 2-4 2 Bedroom/2 Bath $535 4-6 Colorado Suite w/spa $342 2-4 2 Bedroom Premium $626 4-6 Home Phone____________________________ Business Phone One Bdrm Condo $342 2-4 E-Mail (please print clearly) NOTE: Above rates do not include state or local taxes; may not exceed maximum occupancy. Children 14 or under stay free in same room as parents. Check-in time is 4:00 p.m., check-out time is 11:00 a.m. No pets in rooms.

(We will not provide your email address to anyone outside the CME office or Div of TS.)

Dates of attendance: ☐ Thursday YIF ☐ Friday ☐ Friday dinner program (meeting attendees only) Name ☐ Saturday ☐ Sunday

Address Early registration (postmarked before February 1, 2011) $400 Late registration (postmarked after February 1, 2011) $450 City State Zip Saturday night dinner - number of adults including registrant ____ number of children ____ Home Phone Business Phone MC #_____________________ Exp____ Visa #_____________________ Exp______ List of all roommates

If you have a disability and require accommodations in order to fully participate in this activity,

check here.☐ You will be contacted by someone from the planning committee to discuss your specific needs. Arrival Date Departure Date

Please make registration check payable to Division of Transplant Surgery

Deposit/Cancellation Policy: Deposit of 2 nights per unit is required to confirm reservation. Remaining balance including 13.9% tax is required 30 days prior to arrival. Deposit will be refunded, less $75 handling charge per room, if cancellation is received prior to 30 days of scheduled arrival. If cancellation is received less than 30 days prior to arrival date, all monies will be forfeited. Reservations received after January 17, 2011 will be on a space available basis. There is a three-night lodging minimum.

Enclosed is a check or money order for $

, or I authorize deposit amount of

$ to be charged to my credit card. ☐ VISA

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SCIENTIFIC PROGRAM

Saturday Morning Emerging issues in Transplantation Moderators: Lisa Forman and Abraham Shaked TH

Jody Mandic University of Colorado Anschutz Medical Campus Division of Transplant Surgery MS C318 1635 Aurora Court Aurora, CO 80045

Tel: 720-848-0852 • Fax 720-848-0841 Email: [email protected]­­

Course Directors

Igal Kam, MD, University of Colorado Gregory T. Everson, MD, University of Colorado Laurence Chan, MD, PhD, University of Colorado

University of Colorado Faculty Tom Bak, MD Kiran Bambha, MD Scott Biggins, MD James Burton, MD James Cooper, MD

Lisa Forman, MD Alkesh Jani, MD Frederick Karrer, MD Hugo Rosen, MD Michael Wachs, MD

Alex Wiseman, MD Michael Zimmerman, MD Nursing Coordinator

University of Colorado School of Medicine Division of Transplant Surgery Mail Stop C318 1635 Aurora Court Aurora, CO 80045

Tracy Steinberg, RN, MS

Sponsored by: University of Colorado School of Medicine Office of Continuing Medical Education

Guest Faculty Robert Brown, MD

Chief, Division of Abdominal and Organ Transplantation Columbia Presbyterian Medical Center New York, New York

Michael Charlton, MD

Medical Director, Liver Transplantation Mayo Clinic Rochester, Minnesota

Gabriel Danovitch, MD

Medical Director, Kidney and Pancreas Transplant University of California, Los Angeles Los Angeles, California

Sue Dunn, RN, BSN, MBA, CTTC President and CEO of Donor Alliance Organ Procurement Organization Denver, Colorado

Jean Emond, MD

Vice Chair and Director of Transplantation Columbia Presbyterian Medical Center New York, New York

Sheung Tat Fan, MD

Chairman, Department of Surgery and Head of Hepatobiliary & Pancreatic

Surgery and Liver Transplantation University of Hong Kong Hong Kong, China

John Fung, MD

Chairman, General Surgery and Director of Transplant Center Cleveland Clinic Foundation Cleveland, Ohio

John Lake, MD

Medical Director, Liver Transplantation Director, Gastroenterology University of Minnesota Minneapolis, Minnesota

Deepak Malhotra, MD

Transplant Nephrologist University of Toledo Medical Center Toledo, Ohio

Charles Miller, MD

Director, Liver Transplantation Program Cleveland Clinic Foundation Cleveland Ohio

Kim Olthoff, MD

Director, Liver Transplant Program University of Pennsylvania Hospital Philadelphia, Pennsylvania

Elizabeth Pomfret, MD, PhD Director, Adult Live Donor Liver Transplantation Lahey Clinic Medical Center Burlington, Massachusetts

University of Pennsylvania Hospital Philadelphia, Pennsylvania

Roshan Shrestha, MD

Lloyd Ratner, MD

Medical Director, Liver Transplantation Piedmont Hospital Atlanta, Georgia

K. Rajender Reddy, MD

Director, MacLean Center for Clinical Medical Ethics University of Chicago Chicago, Illinois

Michael Rees, MD

Surgical Director, Pediatric Renal and Adult Pancreas Transplant Program UCSF Medical Center San Francisco, California

Director, Renal & Pancreatic Transplant Columbia University Medical Center New York, New York Medical Director, Liver Transplantation Hospital of the University of Pennsylvania Philadelphia, Pennsylvania Director, Renal Transplantation University of Toledo Medical Center Toledo, Ohio

Marty Sellers, MD

Director, Piedmont Liver Cancer Piedmont Transplant Institute Atlanta, Georgia

Abraham Shaked, MD, PhD Chief, Division of Transplantation Surgery

Presented by: The Division of Transplant Surgery, Department of Surgery The Division of Renal Diseases and Section of Hepatology, Department of Medicine University of Colorado School of Medicine and the University of Colorado Hospital

Young Investigator’s Forum •March 3, 2011

Mark Siegler, MD

Peter Stock, MD

James Trotter, MD

Medical Director of Liver Transplant Baylor University Medical Center Dallas, Texas

Course OBJECTIVES/General Information

Target Audience: This program is designed for healthcare professionals who provide patient care at all levels in transplantation. The course is designed for, but not limited to, surgeons, hepatologists, nephrologists, nurses, social workers and pharmacists. Statement of Need/Program Overview: The University of Colorado faculty and guest speakers will address topics on live donor transplantation, immunosuppression and whom to transplant, sickest versus the fittest. Other topics will include hepatitis and updates with organ procurement organizations. Learning Objectives: At the conclusion of this conference, participants should be able to:

CONTROVERSIES IN

TRANSPLANTATION March 4-6, 2011

Young Investigator’s Forum March 3, 2011

Beaver Run Conference Center • Breckenridge, CO

Russell Wiesner, MD

Medical Director, Clinical Trial Services Mayo Clinic Rochester, Minnesota



This program is part of the Colorado Statewide Extended Campus. State funds were not used to develop or administer this program.

■ Analyze donor safety in living donor liver transplantation.

Friday-Sunday, March 4-6, 2011

Beaver Run Conference Center • Breckenridge, CO

CONTROVERSIES IN

TRANSPLANTATION

■ C  ompare outcomes of live donor liver transplantation with deceased donor liver transplantation. ■ I dentify ethical issues requiring management by teams performing live donor transplantation. ■ A  ssess the disease severity and mortality of patients using the Model for End-Stage Liver Disease (MELD). ■ Define the reshaping of organ procurement organizations (OPO). ■ Assess current challenges in kidney transplant.

ACCREDITATION Accreditation Statement: The University of Colorado School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The University of Colorado School of Medicine designates this educational activity for a maximum of 16 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity. CEU and CEPTC credits have been applied for through the International Transplant Nurses Society

Friday Morning

MARCH 4TH 7:00 am 7:30 am 9:20 am 10:00 am

Breakfast/Registration Michael Rees Lloyd Ratner Gabriel Danovitch TBA Session Discussion/Debate Adjourn

Friday Afternoon

3:00 pm Apres Ski Refreshments 3:30 pm Elizabeth Pomfret Igal Kam Sheung Tat Fan Charlie Miller Mark Siegler 6:00 pm Session Discussion/Debate 7:00 pm Adjourn

New challenges in renal transplant

Moderators: Larry Chan and Alex Wiseman

What is new in paired exchange Expanded criteria for diseased donors – ECD/DCD The promotion of living kidney donation in the USA To pump or not to pump

Donor safety in transplantation

Moderators: Kiran Bambha and Jack Lake Donor death in Boston Donor death in Colorado Donor complications in Hong Kong Left lobe vs. right lobe Ethical issues living donation

Friday Evening Current and Future Treatments for HBV and HCV Dinner Program Moderators: Greg Everson and Rajender Reddy 7:00 pm Robert Brown K. Rajender Reddy

Nucleos(t)ides for HBV Direct acting antivirals for HCV

FACILITIES AND SURROUNDINGS

MARCH 5 7:00 am 7:30 am 9:20 am 10:00 am

Just an hour and one-half drive from Denver is the quaint, historic town of Breckenridge. Beaver Run Conference Center is nestled at the base of Peak 9, the largest conference center in the Rockies under one roof. This ski in/ski out resort can put you onto more than 126 ski trails. A free shuttle service can take you to other nearby resorts: Keystone, Copper Mountain and Arapahoe Basin. Other winter activities include ice skating, snowmobiling, sleigh rides and helicopter skiing, just to name a few. After a day of meetings, you can relax in one of Beaver Run’s two heated pools, seven hot tubs, or experience the many fine restaurants and shopping.

Breakfast Peter Stock Transplant in the patient with HIV Michael Charlton IL28b polymorphism and liver allocation John Fung Advances in immunosuppression Sue Dunn Changes in OPO’s John Lake UNOS and the transplant center Session Discussion/Debate Adjourn

Saturday Afternoon

3:00 pm Apres Ski Refreshments 3:30 pm Russ Weisner James Trotter Avi Shaked Kim Olthoff Jean Emond 6:30 pm Session Discussion/Debate 7:00 pm Adjourn 7:30 pm Dinner

Beyond MELD: Who should NOT be transplanted??

Moderators: Hugo Rosen and Scott Biggins

Development and validation of MELD Pitfalls of the MELD Score Realities of transplanting high MELD patients Transplant the fittest: outcome driven Alternatives to MELD

COLORADO MOUNTAIN EXPRESS Sunday Morning Case Presentations Moderators: Roshan Shrestha and Tracy Steinberg

MARCH 6TH 7:00 am 7:30 am 10:00 pm 10:30 pm

Breakfast Case Presentations Marty Sellers Deepak Malhotra Avi Shaked James Cooper Session discussion/debate Adjourn

Colorado Mountain Express shuttle service will offer a discounted rate of $142.60 round trip fare (or $71.10 one way), to meeting participants, from DIA to Beaver Run Resort. Call 1-800-334-7433 and use group code CIT.

Social Event All registrants and their families are invited to a dinner on Saturday, March 5th, 7:00 pm. Dinner, beer, wine and soft drinks will be provided. A block of rooms will be held at Beaver Run Conference Center until January 17, 2011. After that date, rooms will be on a space available basis only. This is peak ski season. BOOK EARLY!

FEES Early registration - postmarked before February 1, 2011 $400 Late registration - postmarked after February 1, 2011 $450 Registration to the Controversies in Transplantation includes the Hepatology Young Investigators Forum. Make check payable to the Division of Transplant Surgery. An 80% refund will be made for cancellations prior to February 1, 2011. No refunds will be made for cancellations after this time or for nonattendance. A comprehensive course syllabus containing outlines and abstracts of the presentations will be given to each registrant. Mail conference registration form and check to: Jody Mandic University of Colorado Division of Transplant Surgery Mail Stop C318 1635 Aurora Court, Aurora, CO 80045 Tel: 720-848-0833 Fax: 720-848-0841 Email: [email protected] Online Registration Register on-line at: http://www.medschool.ucdenver.edu/CME Click on the Register Now button. Payment by Visa or MasterCard is required to register on-line. When you register on-line, you will receive immediate confirmation of your conference registration.

HOTELReservation RESERVATIONForm FORM Hotel

CONFERENCE REGISTRATION FORM

GROUP NAME: Transplant, FOR RESERVATIONS CALL: 1-800-525-2253; in Colorado Register on-line at: http://www.medschool.ucdenver.edu/CME call (970)453-6000 OR MAIL THIS TOP FORM TO: Beaver Run Reservations, P.O. Box 2115, Breckenridge, CO 80424. Last Name______________________________ First Name ____________________________ ACCOMMODATIONS: Please indicate your first and second choices below. Use this (state name as you’d like it to appear on your CME certificate) form for one room only. Other units available upon request. For views, descriptions of ☐ MD ☐ PhD ☐ DO ☐ RN ☐ PA ☐ PharmD rooms and to book your room go to: www.beaverrun.com Type Rate Persons Type Rate Persons Affiliation_____________________________ Address Hotel Room $227 2-4 1 Bedroom Premium $409 2-4 City___________________________________ State____________ Zip Deluxe Studio w/spa $270 2-4 2 Bedroom/2 Bath $535 4-6 Colorado Suite w/spa $342 2-4 2 Bedroom Premium $626 4-6 Home Phone____________________________ Business Phone One Bdrm Condo $342 2-4 E-Mail (please print clearly) NOTE: Above rates do not include state or local taxes; may not exceed maximum occupancy. Children 14 or under stay free in same room as parents. Check-in time is 4:00 p.m., check-out time is 11:00 a.m. No pets in rooms.

(We will not provide your email address to anyone outside the CME office or Div of TS.)

Dates of attendance: ☐ Thursday YIF ☐ Friday ☐ Friday dinner program (meeting attendees only) Name ☐ Saturday ☐ Sunday

Address Early registration (postmarked before February 1, 2011) $400 Late registration (postmarked after February 1, 2011) $450 City State Zip Saturday night dinner - number of adults including registrant ____ number of children ____ Home Phone Business Phone MC #_____________________ Exp____ Visa #_____________________ Exp______ List of all roommates

If you have a disability and require accommodations in order to fully participate in this activity,

check here.☐ You will be contacted by someone from the planning committee to discuss your specific needs. Arrival Date Departure Date

Please make registration check payable to Division of Transplant Surgery

Deposit/Cancellation Policy: Deposit of 2 nights per unit is required to confirm reservation. Remaining balance including 13.9% tax is required 30 days prior to arrival. Deposit will be refunded, less $75 handling charge per room, if cancellation is received prior to 30 days of scheduled arrival. If cancellation is received less than 30 days prior to arrival date, all monies will be forfeited. Reservations received after January 17, 2011 will be on a space available basis. There is a three-night lodging minimum.

Enclosed is a check or money order for $

, or I authorize deposit amount of

$ to be charged to my credit card. ☐ VISA

☐ MASTERCARD

Credit Card # Exp Printed Name

Signature

Mail conference registration form and check to:

Cut Here ✄

SCIENTIFIC PROGRAM

Saturday Morning Emerging issues in Transplantation Moderators: Lisa Forman and Abraham Shaked TH

Jody Mandic University of Colorado Anschutz Medical Campus Division of Transplant Surgery MS C318 1635 Aurora Court Aurora, CO 80045

Tel: 720-848-0852 • Fax 720-848-0841 Email: [email protected]­­