Exploration Grants for Independent Research Group Leaders Programme Objectives The Exploration Grants are intended to enable outstanding research group leaders involved in basic research in medicine, biology or chemistry, to investigate innovative ideas and new lines of research quickly, with a minimum of bureaucracy, and thus, for example, to undertake the preparatory work necessary for research proposals to the DFG or ERC. The grants are not for projects that constitute a logical next step of your research. They are also not available for projects that are planned or in progress under other funding arrangements. Extent of Funding You can apply for a one-off grant of € 60,000 to € 80,000. The grant can be used for personnel and direct project costs (e. g. consumables, minor equipment) as needed. Applications for the group leader’s salary as well as applications solely for the purpose of procuring equipment and/or consumables will not be considered. Conditions of Application You have earned your doctorate with distinction and no more than 12 years ago, have published outstanding papers during your academic career to date and should possess substantial international experience. Your research is basic research in medicine, biology or chemistry; the foundation, however, does not award grants to purely botanical and zoological projects. You have been leading an independent research group at an academic institution in Germany for at least two years. Your publication record already shows your scientific independence (i. e. you have published at least two last-author papers). The project can demonstrably not be pursued under existing funding arrangements, and no application for funds has been or will be submitted to any other organization for this project before the foundation’s decision. Formal Requirements for the Grant Application Your application must contain the following documents (detailed information see Appendix): 1. 2. 3.

4. 5. 6. 7.

Academic CV including awards, fellowships and research grants previously received Diplomas List of publications (numbered and including full list of authors, full paper title, journal title, volume and issue details, page range of article). Please list all your publications and use distinct marks for first- and last-authorships. Please use separate sections for (i) original articles (published or accepted/in press), (ii) reviews, and (iii) manuscripts submitted or in revision. Do not include posters or oral presentations at scientific conferences. Project proposal Employer’s statement of the kind expected by the DFG for Emmy Noether group leaders assuring your independence One copy each of all papers currently in print or submitted for publication, as well as of your five most important published papers Data consent (see pp. 5, 6)

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Selection Procedure The decision on whether to grant funds is made by the Executive Committee of the Boehringer Ingelheim Foundation on the basis of recommendations by the foundation’s Scientific Advisory Board and external peer-reviews. You can recommend potential reviewers and may also name (giving reasons) scientists to whom your proposal should not be presented for evaluation.

Questions about the Programme? Please contact Dr. Sabine Loewer tel: +49 (0) 6131 27 508-12 | e-mail: [email protected]

The Boehringer Ingelheim Foundation The Boehringer Ingelheim Foundation is a charitable foundation. It was established in 1977 by Hubertus Liebrecht (1931-1991), a member of the shareholder family of the company Boehringer Ingelheim. The foundation aims to support excellent scientific work in medicine, biology, chemistry and pharmacy. With its “Plus 3” Perspectives Programme and the Exploration Grants, the foundation supports outstanding junior group leaders. It also provides funds of 100 million euros over ten years for the scientific running of the Institute of Molecular Biology (IMB) and 50 million euros for the development of the life sciences at the University of Mainz. The foundation endows the internationally renowned Heinrich Wieland Prize and the Boehringer Ingelheim in clinical and theoretical medicine at the University of Mainz. Executive Committee of the Foundation

Scientific Advisory Board

Christoph Boehringer Entrepreneur, Heidelberg

Prof. Dr. Dr. Andreas Barner (Chairman) C.H. Boehringer Sohn AG & Co. KG, Ingelheim

Prof. Dr. Dr. Andreas Barner C.H. Boehringer Sohn AG & Co. KG, Ingelheim Prof. Dr. Michael P. Manns Medical School of Hannover, Dept. of Gastroenterology, Hepatology and Endocrinology, Hannover Otto Boehringer (Honorary Chairman) Mainz

Prof. Dr. Dieter Häussinger, Clinic of Gastroenterology, Hepatology and Infectiology, Düsseldorf Prof. Dr. Wieland Huttner Max Planck Institute of Molecular Cell Biology and Genetics, Dresden Prof. Dr. Herbert Waldmann Max Planck Institute of Molecular Physiology, Dortmund

Managing Director Dr. Claudia Walther, Schusterstrasse 46-48, 55116 Mainz, Germany, Tel. +49 (0) 6131 27508-12, Fax +49 (0) 6131 27508-11, [email protected] www.boehringer-ingelheim-stiftung.de

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Appendix Project Proposal General Remarks • The proposal – written in English – should be comprehensible without reading the cited or appended literature. • Please submit a paper copy of your proposal (DIN A4, not stapled or bound). • A pdf-file should be submitted on CD ROM, and to facilitate the reviewers´ work the individual files have to be labelled according to the chapters in this document. • It will also assist the reviewers if you adhere to the following order: 1. General Information 1.1. Applicant  Surname, first name, academic title  Official position; if on a fixed-term contract, please state its duration  Institution and department/ faculty (full name)  Work address  Phone number for contact  E-mail address for contact  Date of birth  Nationality 1.2. Funding  Please state who has been funding your research group and to what extent. 1.3. Estimated total duration  Since when have you been leading your first independent research group?  How long is your current funding expected to run for? 2. Information about the Project 2.1. Title of project 2.2. Subject and area of research  Which subject (e.g. molecular biology) and  On which area of research (e.g. DNA repair) does your project focus? 2.3. Proposed beginning and duration of funding 2.4. Summary Please summarise the hypotheses and the main objectives of your proposed project in generally accessible language and in not more than 2000 characters. 2.5. Project outline 2.5.1. Please describe the proposed project on no more than three pages of DIN A4 paper. Begin by describing the current state of knowledge concisely and exclusively in relation to your own research, mentioning the most significant work by other scientists. Please explain how your own work and preliminary studies to date fit into this context, citing your own papers and other literature. Indicate to which of the open issues in the field you will make a new contribution with the proposed project, and what importance, in your view, it will have for the field.

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2.5.2. Make clear how this project represents or may lead to a new line of research in your group and to what extent it differs from your previous and current work. 2.5.3. Please explain why it cannot be undertaken as part of your ongoing work and/or with other means of support. 2.6. Compliance Every project and study must comply with the applicable laws and conventions in their latest form. 3. Funds Requested 3.1. Total funds requested Please state the total amount of funds requested. 3.2. Breakdown of costs Please state what you intend to use the funds for. 4. Other Information 4.1. Composition of the research group Please list (name, academic title and official position, including fellowship holders) the members of your research group and those who are to participate in the planned project, stating which institution or third-party donor will provide funds in each case. 4.2. Ongoing funding Please state the funds for non-personnel expenditure, that are available annually from the institutions’ budgets or from a third party (please list separately) for your research work. 4.3. Funds committed Please state the resources and amounts (including personnel and material resources) that your university, or a third party has committed to you in writing, as well as their duration. 4.4. Conflicts of interest due to economic activities Please inform us of any conflicts of interest e. g. if you are the owner of a commercial enterprise or own a stake in one. In each case, explain how your research project relates to the company’s production 4.5. Declarations Please sign the following declarations: “A grant application for this project has not been and will not be submitted elsewhere. It is not possible to undertake the project outlined in this grant application on the basis of the resources already available or pending.” “In submitting a proposal for the Exploration Grants Programme of the Boehringer Ingelheim Foundation, I agree to adhere to the DFG’s “Proposals for Safeguarding Good Scientific Practice”.” “I agree to the Boehringer Ingelheim Foundation’s processing and storage of data (electronic and as hardcopy) provided in conjunction with this proposal. This information may be passed on to reviewers and the foundation bodies as part of the review and decision-making process. In addition, I agree to the use of this information for internal evaluation of the foundation’s funding programmes.” 4.6. Signature Please sign the following: “I hereby confirm that all the information given in this application is true and accurate.”

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Data protection information This information explains which data we store on our servers when processing your application and how these data are used. Personal application data In the course of using this service, only those data shall be queried which are required for deciding on and processing your application. The data for this are forwarded to peer reviewers and committee members as part of the Boehringer Ingelheim Foundation evaluation and decision process and also stored and processed for these purposes in the Boehringer Ingelheim Foundation business office. You can approve the usage of your data by the Boehringer Ingelheim Foundation electronically. Your application cannot be processed unless you grant your consent. The data and documents of an application are forwarded to peer reviewers and committee members in the course of the evaluation process. These persons are obligated to handle these data and documents confidentially.

Boehringer Ingelheim Foundation Schusterstrasse 46-48 55116 Mainz Germany

Declarations and obligations I obligate myself to notify Boehringer Ingelheim Foundation immediately about any changes to the data in this online form or the written application. Furthermore: •

•

to comply with all laws relevant to the project and other project-related regulations and in particular, to obtain any required approvals in due time. to use the approved financing solely in the interest of purposefully realizing the funded project.

I agree that •

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information about successful applications will be made generally accessible (e.g. website of the Boehringer Ingelheim Foundation), including the name of the applicant, the institution, the amount of funding, the field of activity, the title, a summary of the research project and the reference to foreign country. the data required by Boehringer Ingelheim Foundation for processing the application shall be electronically stored and processed and also forwarded to peer reviewers and foundation committees as part of the evaluation and decision-making process. I am aware that I can revoke the publication in electronic or written form within 4 weeks of receipt of the approval letter.

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Datenschutzhinweise Diese Hinweise erläutern, welche Informationen wir auf unseren Servern im Rahmen Ihrer Antragsstellung erfassen, und wie diese Informationen genutzt werden. Personenbezogene Antragsdaten Im Laufe der Nutzung dieser Dienstleistung werden nur Daten erfragt, die für eine Bearbeitung und Entscheidung Ihres Antrags erforderlich sind. Diese Daten werden hierfür im Rahmen des Begutachtungs- und Entscheidungsverfahrens der Boehringer Ingelheim Stiftung an Gutachter und Gremienmitglieder weitergeleitet sowie in der Geschäftsstelle der Boehringer-Ingelheim-Stiftung zu diesen Zwecken gespeichert und verarbeitet. Die Einwilligung zu dieser Nutzung der Daten durch die Boehringer-Ingelheim-Stiftung kann elektronisch erklärt werden. Nur bei Erklärung des Einverständnisses kann der Antrag bearbeitet werden. Im Verlauf des Antragsbearbeitungsprozesses werden Daten und Dokumente eines Antrags an Gutachter und Gremienmitglieder weitergeleitet. Diese Personen sind zur vertraulichen Behandlung dieser Daten und Dokumente verpflichtet.

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Informationen über erfolgreiche Anträge allgemein zugänglich gemacht werden (z. B. Website der Boehringer-Ingelheim-Stiftung), einschließlich des Namens des Antragstellenden, der Institution, Fördersumme, Fachgebiet, Titel, Zusammenfassung des Forschungsprojekts und Auslandsbezug. die zur Bearbeitung des Antrags erforderlichen Daten von der Boehringer-Ingelheim-Stiftung gespeichert und verarbeitet sowie im Rahmen des Begutachtungs- und Entscheidungsverfahrens an Gutachtende und Gremien der Stiftung weitergeleitet werden. Mir ist bekannt, dass ich der Veröffentlichung in elektronischer oder schriftlicher Form nach Erhalt des Bewilligungsschreibens innerhalb einer Frist von vier Wochen widersprechen kann.

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Boehringer Ingelheim Foundation Schusterstrasse 46-48 55116 Mainz Germany Phone +49 (0)6131 27 50 8 0 Fax +49 (0)6131 27 50 8 11 Email: [email protected] Web: www.boehringeringelheim-stiftung.de