R a n dy K r ay,
Aia
Senior Vice President | Science + Technology Director of Programming and Planning Randy Kray has over 20 years of specialized architectural experience in strategic planning, programming, and design of scientific facilities. He is a strategic leader in HOK’s Science + Technology group, and a leading expert in the design of highly complex scientific facilities, including labs in high containment biosafety facilities, animal facilities, nanotechnology facilities, and other interdisciplinary academic and governement research facilities. As a recognized global thought leader on high containment facility design and the integration E d u c at i o n
University of Manitoba Masters of Architecture , 1993 University of Manitoba Bachelor of Environmental Science, 1989 P r o f e s s i o n a l Reg i s t r at i o n s
Architecture: Georgia, Manitoba, Ontario (submitted) M em b e r s h i p s
American Institute of Architecture American Biological Safety Association (ABSA) European Biological Safety Association European Research Infrastructure on Highly Pathogenic Agents (ERINHA) American Association for Laboratory Animal Science (AALAS)
of design/construction/commissioning delivery systems for complex science and technology missions, he is a frequent speaker at scientific conferences. He regularly published articles on these subjects and has contributed to both national and international design and safety standards, including the latest CDC/NIH Biosafety in Microbiological and Biomedical Laboratories (BMBL) 5th Edition. Experience
US Centers for Disease Control and
National Institutes of Health
Prevention
NIAID Integrated Research Facility*
Emerging Infectious Diseases Laboratory*
Fort Detrick, Maryland
Atlanta, Georgia
Role: Principal Planner and Containment
Role: Containment Planner and Architect,
Architect. New 144,000 gsf high
Construction Services Design Leader
containment research & analysis facility
(BSL-4/BSL-3E areas). New 440,000 gsf
that includes 25,000 sf BSL-4 laboratory
infectious disease research facility and
and animal facility, BSL-2 laboratories, and
central energy plant on the CDC’s Atlanta
research support areas. This BSL-4 facility is
campus. The facility includes approximately
the first to provide fully-integratedadvanced
20,000 square feet of BSL-4/3enhanced
medical equipment, patient support
space, organized into four multi-pathogen
infrastructure, and whole-animal imaging
and multi-program suites. BSL-2 and BSL-3
in an ABSL- 4 environment, including MRI,
diagnostics laboratories and BSL-3 animal
PET/CT, SPECT/CT and X-ray fluoroscopy
facility.
modalities.
US Centers for Disease Control and
US Army Medical Research Institute
Prevention
of Infectious Diseases (USAMRIID)
NCID/DVBID Replacement Laboratory*
Replacement Facility *
Fort Collins, Colorado
Fort Detrick, Maryland
Role: Containment lab and vivarium planner.
Role: Principal Lab Planner. Development
New replacement laboratory facility for
of Design Brief, Master Planning Study and
the CDC in Fort Collins, Colorado jointly
Design/Construction services for a new
houses the National Center for Infectious
Biodefense Campus at Ft. Detrick. Phased
Diseases (NCID) and Division of Vector-
implementation of 835,390 gsf of new
Borne Infectious Diseases (DVBID). The
Biomedical Research and Testing Facilities
building consists of offices, BSL-2 and BSL-3
that include offices, BSL2, BSL3, and
laboratories and their associated support
BSL4 laboratories for infectious diseases
labs; small animal BSL-3 vivarium space; and
and toxicology, animal facilities and related
an BSL-3 insectary. A feature of this project
infrastructure. The state-of-the art facility
is a 25,000 gsf BSL-3 insectary, which is
will significantly increasing laboratory and
highly integrated with the laboratory and
vivarium research capabilities for BSL-2,
animal research components.
BSL-3E and BSL-4 biomedical and clinical research.
* experience prior to joining HOK
h o k .c o m
R a n dy K r ay,
AIA
S p ea k i n g E n g a g eme n t s
Experience
“Achieving Sustainability in High
National Biotechnology Centers for
University of Florida
Performance Buildings” Open Buildings
Advanced Product Development (NBCAPD)
Communicore BSL-3 Animal
Conference - Architecture in the Fourth
Medical Countermeasure T&E Facility*
Facility Renovation*
Dimension, Boston MA (2011)
Fort Detrick, Maryland
Gainesville, Florida
“The Art and Science of Biocontainment
Role: Lab Planner and Biocontainment
Role: Containment Lab Planner NIH funded
Expert. Development of space program
renovation and remodeling of 55,333 sf
(Brief) and Master Planning study for a new
in the Communicore Animal Care Facility,
inter-agency animal Testing and Evaluation
including expanding the ABSL-3 suite and
(T&E) facility for biodefense and infectious
providing approximately 5,000 sf of flexible
disease countermeasure development
lab space.
Facility Design, Construction and Operation,” American Biological Safety Association Meeting, Anaheim, CA (2011) “Commissioning & Validation for Laboratory Waste Autoclaves,” International Veterinary Biosafety Workgroup General Meeting, Copenhagen, Denmark (2011) “Agriculture Pathogens: Planning, Design and Operational Strategies,” Canadian Biosafety Symposium, Toronto, Ontario, Canada (2011) “Defining user Requirements for BSL4 Facilities - What does the architect need to know,” ERINHA (European Research Infrastructure on Highly Pathogenic Agents) Workshop 4.1, Lyon, France (2011) “Nanotechnology Safety: Applying Prevention through Design Principles to Nanotechnology Facilities,” Institute of Environmental Sciences and Technology (IEST), Working Group WG-CC205 Workshop, Chicago, IL (2011)
at the Ft. Detrick biodefense campus. The facility is programmed to provide
Tulane University
approximately 460,000 GSF of ABSL-2,
National Primate Center,
ABSL-3, and ABSL-4 GLP animal testing
Regional Bio-Containment Lab*
space and support space to validate new
Covington, Louisiana
biodefense and emerging infectious disease
Role: Containment Lab Planner. 2,166gm²
countermeasures under the new FDA Animal
BSL-3 bio-containment, vivarium and
Rule.
laboratory for the NIH. His role was biocontainment designer responsible for
New York State Department of Health,
the development, protocol-to-planning
Wadsworth Centre*
coordination, & documentation of the
Albany, New York
aerobiology lab, including the primary
Role: Principal Planner. The planning study of
containment equipment & integration into
a new 23,225gm² of laboratory facilities on
ABSL-3.
multiple sites and site selection services for a new high containment facility.
Lovelace Respiratory Research Institute ABSL3 Facility Expansion*
The Qualification Process Adapted to
University of Florida
Albuquerque, New Mexico
Containment Facility Design and Delivery,”
Pathogen Research Facility*
Role: Principal Lab Planner. 4,000 sf
The International Centre for Infectious
Gainesville, Florida
enhanced ABSL-3 facility expansion.
Diseases (ICID), Canadian Biosafety
Role: Containment Lab Planner. This 10,000
The facility is to include additional animal
Symposium, Winnipeg, Canada (2010)
square meter Pathogen Research Facility
housing rooms, laboratories, procedure
“Current Best Practices for Influenza
(PRF), home of the Emerging Pathogens
room and freezer/refrigerator room. The
Institute, will integrate disciplines that
existing supporting infrastructure, such as
have not traditionally collaborated at the
steam sterilization, change/shower rooms,
Research and Diagnostic Facilities - Risk, Safety and Design,” Tradeline International Conference on Biocontainment Facilities, St. Petersburg, Florida (2010) “Biocontainment Design and Risk Assessment Safety System Integrity Approaches and Practice,” CDC International Symposium on Biosafety, BSL-4 Users
University of Florida to attack problems
effluent decontamination system (EDS),
of emerging and re-emerging pathogens.
PPE decontamination, etc will be used to
Project include BSL-2 (QC2/PC2), BSL-3
support the new space. It is anticipated that
(QC3/PC3) laboratory, animal and plant
the majority of the new construction will be
growth space, bioinformatics, and BSL-2
performed while the current facility is fully
(PC2) and BSL-3 (PC3) greenhouses.
operational.
Group, Atlanta, GA USA (2009)
4 LEED Certified * experience prior to joining HOK
h o k .c o m
R a n dy K r ay,
AIA
S p ea k i n g E n g a g eme n t s
Experience
“Risk-based Planning for Leading-Edge
4 University of California
Bioscience Research Centre*
Work Environments and Future Changes in
Western National Bio-defense and Emerging
Melbourne, Australia
Safety Protocols,” Tradeline International
Disease Research Facility*
Role: Principal Containment Planner.
Conference on Biocontainment Facilities,
Davis, California
Containment architect and laboratory
Washington, DC (2008)
Role: Principal Planner. Programming
planners for a Public Private Partnership (P3)
“Imaging and biocontainment – A single
for a 3,251nm² BSL 4 Laboratory. Co-
design and construction team. The project
authored original UC Davis Feasibility
was sponsored by a joint venture between
Report, completed prior to NIAID NBL
the Government of Victoria and La Trobe
program announcement. Participated in
University in Australia. The total net area of
user interviews; developed original planning
14,660 M2 included physical containment
concepts for BSL4/BSL3- Ag laboratory
level 2 (PC2) and level 3 (PC3) laboratories,
and animal spaces based on bio-defense
small animal vivarium, plant research
research needs. Retooled original program
laboratory/greenhouses and large animal
based on stated NIAID bio-defense
post-mortem space.
equipment platform for clinical, research, and outbreak-readiness,” Tradeline International Conference on Biocontainment Facilities, Washington, DC (2008) “New Technologies in Containment Facilities” CDC International Symposium on Biosafety, Atlanta, GA (2008) “Core Issues in Retrofitting an Existing Facility” CDC International Symposium on
strategies and FDA drug development guidelines (current and draft); acted as peer
Pirbright Site Redevelopment Programme*
reviewer for development of functional
Pirbright, United Kingdom
concept diagrams, blocking and stacking
Role: Principal Planner and Containment
diagrams based on master plan concepts,
Architect, Commissioning and Validation
development of fully functional concept
Consultant. A new 140,000 sf containment
plans incorporating diagrammatic concepts.
level 4 facility for the UK Institute for
Collaborator and contributor to rooms
Animal Health at Pirbright. The redeveloped
layout drawings for clinical research, basic
Pirbright site will include the construction
BSL2 laboratories, BSL3/BSL4/BSL3-Ag
of a new laboratory building, gatehouse
laboratories, ABSL3 and ABSL4 animal
and energy centre, and new landscape
“Ideas of Planning Safely in Academic
holding, aerobiology and ABSL2 animal
and infrastructure works. The facility is
Laboratory Design” University Safety &
support spaces.
designed to allow flexible multi-program
Biosafety, Atlanta, GA (2008) “Design of ABSL 1-4 Animal Facilities” CDC International Symposium on Biosafety, Atlanta, GA USA(2008) “Installing Flexible Film Isolators to Satisfy Changing Regulations Cost-Effectively with Minimal Disruption to Research” American Biological Safety Association Meeting, Reno, NV.USA(2008)
research and reference laboratory work with
Health Association (USHA), London, UK (2008)
University of California
a broad spectrum of viruses of veterinary
“Multi-Pathogen, Multi-Protocol Facility
CNSI BSL-3 Laboratory*
significance including Foot and Mouth
Los Angeles, California
Disease (world reference lab), Blue Tongue,
Role: Project Director and Principal
Newcastle Disease, and emerging zoonotic
Planner. 6,500 sf core and shell fit-out to
diseases. The facility is designed to meet
provide an enhanced BSL-3 laboratory for
the UK SAPO (veterinary) Level 4 and
high throughput robotic diagnostics and
ACDP (human health) Level 3 containment
sample repository. Main components of the
requirements, and will comply with the new
program are an open flexible multi-station
UK single human/animal/GMO regulatory
automation laboratory and a million sample
framework. The main lab building features
automated biobank system, operating under
a highly evolved containment strategy
USDA enhanced BSL-3 protocols. BSL-2
– both physical containment and work
and BSL-3 laboratories and equipment
management systems – to minimize the
control/observation rooms support the high
impact of containment separation and allow
throughput logistics requirements.
the maximum staff interaction without
Design Solutions” Tradeline International Conference on Biocontainment Facilities, San Diego, California (2007) “Optimization of High Containment Secondary Barrier Performance and Proportionate Site Validation Methods” American Biological Safety Association Meeting, Nashville Tenn. (2007) “Overview of Lessons Learned in Europe, Asia and the Americas” Eagleson Institute International Biocontainment Design Colloquium, Freeport, Maine. (2007) “Integration of Imaging Equipment and Other
compromise to safety and security.
New Technologies into Biocontainment
University of Saskatchewan
Facilities and Vivariums” Eagleson Institute International Biocontainment Design Colloquium, Freeport, Maine. (2007) * experience prior to joining HOK
h o k .c o m
R a n dy K r ay,
AIA
S p ea k i n g E n g a g eme n t s
Experience
“High Containment Fire Safety Design and
International Vaccine Centre (InterVac)*
Veterinary Lab Addition*
Approval Process for the Boston Medical
Saskatoon, Canada
Laramie Wyoming
University NEIDL” Eagleson Institute
Role: Principal Planner for Project Brief and
Role: Principal Containment Lab Planner
International Biocontainment Design
Concept Design. New 116,221 gsf large
and Architect. Design of a new addition
Colloquium, Freeport, Maine. (2007)
animal vaccine research and development
and renovations to existing facilities for the
“Flattening Biocontainment: An International
facility designed to meet Canadian
University of Wyoming, the Wyoming State
AP3LA (US BSL-3Ag) (QC3) containment
Veterinary Laboratory (WSVL) and Wyoming
requirements, with accompanying
Game & Fish Department – Wildlife Disease
Perspective of Trends in Containment” Annual Conference of the European Biosafety Association, Heidelberg, Germany (2007) “Vivaria without walls – The new animal housing solution” Tradeline’s Animal Research Facilities Conference, Hilton Head, South Carolina (2007) “Multi-modal, whole-animal, in vivo imaging inside a biocontainment environment”Tradeline’s Animal Research Facilities Conference, Hilton Head, South Carolina (2007) “Acceptable Air Leakage Criteria for Biocontainment Barriers” American Biological Safety Association Annual Conference, Boston, MA. (2006) “Fire Suppression Design Strategies for Boston University Medical Center National Emerging and Infectious Diseases Laboratory” International Veterinary Biosafety Working Group Conference,
containment level 3 (CL-3) research
Laboratory (WGFD-WDL). to modernize and
laboratories.
accommodate state animal health programs for endemic and emerging infectious disease
Imperial College
surveillance and diagnostics. The new
DEFRA 4 Feasibility Study*
addition and renovation includes BSL-2 and
London, United Kingdom
BSL-3 laboratories and post mortem areas
Role: Project Director and Principal Planner.
as well as support facilities to total 9,102 net
Feasibility and Masterplan services for
assignable square feet (NSF) / 20,730 gross
a new specialist teaching, research and
square feet (GSF). Construction completion
biology laboratory facility at Imperial
and building occupation in 2011.
College London’s School of Medicine. The facility includes 600 sq. m SAPO4 (QC-4)
University of Illinois at Chicago
and ACDP3 (PC-3) enhanced containment
National Centre for Bio-defense and
laboratories, ABSL3 vivarium, BSL3
Emerging Infectious Diseases, Facility
insectary, and electron microscopy suite. The
Feasibility Study*
scheme has been developed with Biosecurity,
Chicago, Illinois
Biosurety and Health and Safety as principle
Role: Principal Planner. Participation in
drivers as befits the complex nature of the
this project was in an overview role, mainly
scheme and its location.
responsible for the translation of UIC’s drug discovery and drug development
Emory University
expertise into an complete bio-defense
Yerkes National Primate Center, Dual
research program agenda, translated into
“Issues in Infectious Disease Research and
Function Primate Facility*
a functional program. Upon completion of
High Containment Facility Design” Mid-
Atlanta, Georgia
the functional program, involvement in the
Atlantic Bio Conference, Washington, DC
Role: Project Principal and Containment
project was mainly as a peer reviewer during
(2006)
Architect. Architecture, engineering and
the development of the design and costing
“One Step Beyond – The Next Measure in
commissioning peer review of 20,765 square
models.
Singapore (2006)
the Evolution of Biodefense. Infrastructure Requirements and Potential Impact on the Research Park” Association of University Research Parks (AURP) Annual Meeting, Atlanta, GA (2006) “Planning and Design Issues in High Containment Facilities” Eagleson Institute International Biocontainment Design Colloquium, London, UK (2006)
foot, $11 million ABSL-3/ABSL-2 nonhuman primate research facility. The facility
Parkville Comprehensive Cancer Centre*
incorporates two floors of primate research:
Melbourne, Australia
an ABSL3 Vivarium and infectious disease
Role: Project Director. Containment and
research floor with capacity for 108 animals;
healthcare planning for a Public Private
and a separate floor dedicated to the
Partnership (P3) design and construction
Transplant Medicine Facility with capacity for
team. The project involves the establishment
housing up to 80 animals in quarantine and
of a formal collaboration between Peter Mac
up to 168 NHPs post-transplant.
Hospital, the Royal Melbourne Hospital, the
Wyoming State University
University of Melbourne, the Melbourne
* experience prior to joining HOK
h o k .c o m
R a n dy K r ay,
AIA
S p ea k i n g E n g a g eme n t s
Experience
“BSL-3 and vivaria -- options for where the
branch of the Ludwig Institute for Cancer
University of Manitoba
barrier goes and the impact on operations
Research, the Royal Women’s Hospital and
Monsanto Crop Research Centre*
and costs” Tradeline International
the Walter and Eliza Hall Institute for Medical
Winnipeg, Canada
Conference on Biocontainment Facilities, St.
Research. The Total estimated Investment is
Role: Project Designer and Architect.
Petersburg, Florida (2005)
$1 billion. Total area 93,000 m2.
19,200 sq.ft. research facility included:
“Advanced Technologies in Containment” Eagleson Institute International Biocontainment Design Colloquium, Freeport, Maine (2005) “Lessons Learned in BSL3-Ag Facilities”Eagleson Institute International Biocontainment Design Colloquium, Freeport, Maine (2005) “Cost Effective Facility Design Strategies for Biocontainment Facilities Security” Tradeline International Conference on Biocontainment Facilities, St.Petersburg, Florida (2004) “Biocontainment Facility System Redundancy and the Quantification of Risk,” Tradeline International Conference on Biocontainment Facilities, St.Petersburg, Florida (2003)
BSL2 research laboratories, research office Texas Tech University
space, administrative offices and CL-2
Advanced Research Centre*
research green houses. Involved combination
Lubbock, Texas
of renovation of historical campus building
Role: Principal Planner. Member of the
and new construction. Design incorporates
team responsible for the development of
master planning for future expansion.
this Advanced Research Facility which includes a BSL- 4 laboratory for Texas Tech University. The project was designed in response to U.S government initiative to support academic research related to issues regarding and the inherent risk of infectious agents or chemicals being used as offensive weapons. It contains leading-edge technical detection, diagnostic and research systems. Undertaken in joint venture, the facility is approximately $98 million and completed in 2004.
p u b l i c at i o n s
“Perspectives in Biocontainment – Waste Matters” ALN Magazine, Vol. 10 No. 4. May/ June 2011 “Perspectives in Biocontainment – The Containment Barrier – Testing it Right, Part 2” ALN Magazine, Vol. 10 No. 2. March 2011 “Perspectives in Biocontainment – The Containment Barrier – Testing it Right, Part 1” ALN Magazine, Vol. 10 No. 1. January/ February 2011 “Perspectives in Biocontainment – Commitment to Containment” ALN Magazine, Vol. 9 No. 1. January 2010 “Perspectives in Biocontainment – The
University of Manitoba Agricultural and Food Sciences Building* Winnipeg, Canada Role: Principal Planner and Designer. New 7,500 sq. m agricultural teaching and research facility for the University of Manitoba, the facility includes: teaching laboratories, research laboratories, audiovisual and digital media classroom spaces with remote satellite broadcast capabilities, support spaces, administration offices and natural light filled meeting places for researchers and students.
BMBL 5th Edition: Model for Continuity and Change” ALN Magazine, Vol. 9 No. 2. March 2010 “Perspectives in Biocontainment – Simple Airflow Strategies Provide You the Greatest Reliability” ALN Magazine, Vol. 9 No. 3. April 2010 “Perspectives in Biocontainment – Pressure, Volume and Directional Airflow Objectives” ALN Magazine, Vol. 9 No. 5. July/August 2010
4 LEED Certified * experience prior to joining HOK
h o k .c o m