Smart technology for individual filling tasks
Dosing systems and equipment F I R S T BRAND – your expert partner, ready to offer solutions for
your
dosing
require-
ments. Individualized design, development, construction, mechanical and electrical installation and commissioning – all from one source! ■ High-precision dosing of liquid media ■ Sampling and dosing for research and industry laboratories in the fields of chemistry, medicine, biotechnology and food ■ Suitable for sensitive applications and also filling under sterile conditions available ■ Disposable plastic dosing components – both sterile or nonsterile ■ Volume range from 50 µl to 100 ml ■ Patented dosing technology
C L A S S · B R A N D
Design and technology Innovation and experience to offer solutions for your dosing requirements
Our innovative and high-precision dosing technology incorporates advanced system components from our world-renowned Liquid Handling instruments. They are combined with highquality,
reliable
component
groups and modules from automation and control technology according to your requirements. BRAND provides single- and multi-channel dosing systems and electronic dosing control systems.
Our project planning takes you from concept definition through design and production, hardware planning and programming, all the way to on-site system commissioning – everything from one source!
BRAND – Your reliable partner with years of experience in mechanical systems including hardware and software design.
Two designs – One operating principle! FD (fully disposable) dosing module
Dosing module with autoclavable, stainless steel media distributor
For the consumer area
For routine use in sensitive areas
Dispensing cartridge Valve head
Dosing module mount Membrane filter Membrane filter
Level control container
Stainless steel autoclaving set including media distributor, tube holder and level control container module
Tube connection
Tube connection to the storage container
Functionality of the seripettor ® dispensing system
Advantages of the seripettor ® dispensing system
Plug´n Play
The media is usually supplied
the piston conveys the medium
• The dispensing cartridges, membrane filter, and pre-mounted
Based on the seripettor® dis-
assembly can be conducted un-
The FD dosing module makes CIP/SIP processes a thing of the
for example by using a peristal-
through the valve system in the
valve heads are disposable and easily replaceable without using
pensing technology an entirely
der validated cleanroom condi-
past, and eliminates all the associated system technology. This
tic pump through a media feed
valve head and delivers it via the
tools. They can be supplied sterile if needed
novel, completely replaceable,
tions (ISO 14644-1, Class 8).
means:
tube to the level control con-
dispensing tube or a flexible dis-
single-use dosing module made
The
tainer. This provides a constant
pensing tube.
of exceptionally high quality
ing the dosing module means
system pressure and serves as
The piston movements are ac-
plastics has been developed.
that all media-carrying compo-
• No more cleaning and sterilization validations necessary
an air trap. An upward aspiration
tuated by one or more axles.
The modular design of the seg-
nents in the dosing system can
• No residue due to cleaning errors
ments allows an individual as-
be quickly, easily and cleanly
stroke fills the dispensing car-
• The media distributor and level control container are easy to disassemble, clean and autoclave • No calibration of the dosing system is necessary after replacing the disposable items
Advantages of the FD dosing system
simplicity
of
exchang-
tridges with media via a media
• The low dead-space design for media-carrying channels means
sembly. The system offers the
changed by a plug´n play pro-
distributor channel. The subse-
minimal loss of media during cleaning or when changing media
greatest possible flexibility in the
cess.
quent downward movement of
• Design provides low maintenance overhead and minimal downtime • High precision dosing is combined with long-lasting durability
dosing
module
arrangement.
At BRAND, manufacturing and
• No additional expenditures for complex cleaning systems
• No more cleaning required (for huge time savings and productivity gains) • Minimal downtime in production facilities • Reduction of process risks • Cross-contamination is largely eliminated
Essential components are patent protected.
The seripettor ® dispensing system
A proven concept – the bottle-top dispenser seripettor®
seripettor® components – modified for use in high-performance dosing systems
Operating principle
Versatile
The operating principle of our
An upward movement of the
BRAND dosing systems, us-
The direct displacement princi-
dosing systems is based on the
piston fills the dispensing car-
ing the seripettor
technolo-
ple makes them especially suit-
advanced bottle-top dispenser
tridge with liquid.
gy, can be integrated into com-
able for dosing low-viscosity,
®
from BRAND. For
A subsequent downward move-
plex filling and packaging lines
aqueous, and many other types
years, this instrument has en-
ment of the piston delivers the
as needed, and can be custom-
of media.
abled simple and precise dis-
liquid through the dispensing
ized to individual specifications.
pensing of media directly from
tube via a valve system.
Thus, they offer a broad range
seripettor
®
the storage bottle, and it has
of possible applications, and are
Volume ranges from 50 µl to
been used successfully in di-
well suited for high-throughput
25 ml per dosing stroke.
verse laboratories all over the
filling lines.
world. The piston-cylinder principle is ideally adapted for use in precision dosing systems.
The centerpiece of the system: The easily replaceable seripettor® dispensing cartridge available in three sizes: 2 ml, 10 ml and 25 ml; the piston (PE) and cylinder (PP) are also available sterile
Examples of the accuracy of the seripettor® dispensing system: Typically achievable tolerances,
Nominal volume:
using examples of dosing
Dispensing cartridge
experiments with an aqueous, low-viscosity medium. To determine an exact value for your application, dosing tests must be carried out with the original media.
2 ml seripettor® Dispensing cartridge
0.05 ml
0.25 ml
1.0 ml
±1% ± 0.5 µl
± 0.5 % ± 1.25 µl
± 0.5 % ± 5 µl
±4% ± 10 µl
±1% ± 10 µl
10 ml seripettor® Dispensing cartridge 25 ml seripettor® Dispensing cartridge
5 ml
10 ml
± 0.5 % ± 25 µl
± 0.3 % ± 30 µl
± 0.5 % ± 25 µl
± 0.3 % ± 30 µl
25 ml
± 0.3 % ± 75 µl
If your requirements differ from these, please contact us. We will develop a solution for you! Operating limitations of the seripettor® dispensing technology Temperature:
Viscosity (max.): 2 ml dispensing cartridge: 300 mm /s
+15 °C to + 40 °C, agar nutrient media up to
10 ml dispensing cartridge: 150 mm2/s
a maximum of 60 °C
25 ml dispensing cartridge: 75 mm /s
Density: maximum 2,2 g/cm3
2
2
Dispenser dosing system for critical applications For dosing critical media, we
In these systems, the dispens-
expenditures to a minimum,
design
even with reusable technology.
solutions
ing cartridges are made exclu-
from standard components from
sively from durable, long-lasting
the wide selection of BRAND
components with high chemical
Volume ranges from 0.25 ml to
bottle-top dispensers:
resistance.
100 ml per dosing stroke.
Foremost these are used for
A high priority is developing a
critical reagents such as acids,
maintenance-friendly
alkalis, organic solvents, or
design, which reduces cleaning
customized
system
high-viscosity media.
Single-channel Dispensing system with x/y/z portal
Know-how through experience For over 60 years. The name BRAND signifies the highest quality in laboratories all over the world. This is true for our demanding line of liquid handling products as well as for our well-known BLAUBRAND ® glass volumetric instruments, and our extensive range of disposable and reusable plastic products.
Quality is our business goal
Dosing systems and
OEM plastic injection-
equipment from BRAND
molded products by BRAND
From the design and selection
The
accumulated
Our strength lies in our exper-
An interdisciplinary team of spe-
of the best raw materials to the
during the development of our
tise in developing and manu-
cialists develops custom solu-
quality assurance systems in
standard
products
facturing technically demanding
tions for specific requirements –
our own company, we strictly
provides a solid foundation for our
plastic products characterized
from concept to development to
control each step along the way
dosing systems. This, together
by outstanding optical proper-
the implementation of high-per-
to the final product. With our
with our many years of experience
ties and defined surface consis-
formance products.
dedicated staff and advanced
in equipment and system design,
tency. Mainly thermoplastic ma-
production technology, we have
makes us your expert partner,
terials are used in production,
everything necessary to offer
ready to offer solutions for your
under cleanroom conditions of
our customers the highest prod-
specific dosing requirements.
class 8, 7 and 5 (ISO 14644- 1)
experience
laboratory
uct performance at an attractive
when required.
price.
9944 94 · Printed in Germany · 5/0914
BRAND®, seripettor® and BLAUBRAND® are trademarks of BRAND GMBH + CO KG, Germany. Our technical literature is intended to inform and advise our customers. However, the validity of general empirical values, and of results obtained under test conditions, for specific applications depends on many factors beyond our control. Please appreciate, therefore, that no claims can be derived from our advice. The user is responsible for checking the appropriateness of the product for any particular application. Subject to technical modification without notice. Errors excepted.
BRAND GMBH + CO KG · P.O. Box 11 55 · 97861 Wertheim · Germany Phone: +49 9342 808-0 · Fax: +49 9342 808-98000 · E-Mail:
[email protected] · Internet: www.brand.de