CURRICULUM VITAE Mark A Carlson, MD CAMPUS ADDRESS:

Department of Surgery-General Surgery 983280 Nebraska Medical Center Omaha, NE 68198-3280 Phone: (402) 559-7192

EDUCATION 1980 - 1984 1985 - 1989

BA, College of Wooster, OH MD, Case Western Reserve School of Medicine, OH

POST DEGREE TRAINING 07/1989 - 06/1995 07/1991 - 06/1992 07/1993 - 10/1993 07/1995 - 06/1996 07/1996 - 06/1999

Resident, General Surgery, Medical College of Wisconsin, Milwaukee WI Research Fellow, GI Motility, Medical College of Wisconsin, Milwaukee WI Registrar, General Surgery, Royal Devon and Exeter Hospital, Exeter England Fellow, Minimally Invasive Surgery, Medical College of Wisconsin, Milwaukee WI Research Fellow, Wound Healing, University of Texas Southwestern Medical Center, Dallas TX

CONTINUING EDUCATION AND TRAINING 01/2016 - 2016 02/2016 - 2016

Quality and Safety Education Program, UNMC Patient Safety Certificate Program - Intermediate, Johns Hopkins University School of Medicine

ACADEMIC APPOINTMENTS 2011 - Present 2011 - Present 2010 - 2011 2005 - 2011 1999 - 2005 1996 - 1999

Professor, Surgery, UNMC, Omaha VA Medical Center, Omaha, NE Professor (Courtesy), Genetics, Cell Biology and Anatomy, UNMC, Omaha VA Medical Center, Omaha, NE Associate Professor (Courtesy), Genetics, Cell Biology and Anatomy, UNMC, Omaha VA Medical Center, Omaha, NE Associate Professor, Surgery, UNMC, Omaha VA Medical Center, Omaha, NE Assistant Professor, Surgery, UNMC, Omaha VA Medical Center, Omaha, NE Assistant Clinical Professor, Surgery, University of Texas Southwestern Medical Center, Dallas, TX

CERTIFICATIONS AND LICENSES 2007 - 2018 2016

Surgery, American Board of Surgery 42975 Physician, State of Nebraska, Nebraska, 21117

GRANTS AND CONTRACT SUPPORT Active Title: ID Number: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

Nebraska Center for Nanomedicine 5P20GM103480-08 DHHS/NIH/NIGMS 2013 - 2018 $17,341,073 $1,500,030 Co Investigator (Bronich)

Title: ID Number: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

Hemostatic Patch Phase II

Title:

Technologies for Hemostasis and Stabilization of the Acute Traumatic Wound W81XWH-11-1-0836 U.S. Army 2011 - 2016 $5,033,983 $4,751,904 Principal Investigator

ID Number: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

LNK Chemsolutions, LLC 2014 - 2016 $150,000 $99,668 Principal Investigator

Pending Title:

Nanofiber-based Delivery of Combined Immune-modulating Compounds to Minimize Infection and Enhance Wound Healing

ID Number: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

DHHS/NIH/NIGMS 2017 - 2022 $2,980,974 $2,404,179 Co Investigator (Xie)

Title:

Novel Derivatives of Pyrrolomycin as Anti-MRSA/biofilm Agents Log #

DM170026P2 ID Number: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

National Strategic Research Institute 2017 - 2019 $151,500 $100,000 Principal Investigator

Completed Title: ID Number: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

Tensiometer for Bandage-wound Adhesion Studies

Title: ID Number: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

Hemostatic Patch LNK-UNMC-NEDED-001 LNK Chemsolutions, LLC 2012 - 2014 $70,000 $70,000 Principal Investigator

Title: ID Number: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

Development of New Hemostatic Dressings 5R43HL096194-02 LNK Chemsolutions, LLC 2009 - 2011 $157,728 $107,298 Principal Investigator

Title: ID Number: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

Efficacy of a Hemostatic Bandage Embedded with Recombinant Factors 25-1106-0020-204 University of Nebraska - Lincoln 2007 - 2009 $136,708 $91,794 Principal Investigator

Title: ID Number: Funding Agency: Project Period:

Regulation of Fibroblast Survival in the Collagen Matrix 5K08GM000703-05 DHHS/NIH/NIGMS 2001 - 2006

DOD-DEPSCoR 2014 - 2015 $57,360 $57,360 Principal Investigator

Total Dollars: Direct Cost: Role:

$540,854 $501,184 Principal Investigator

NON-SPONSORED / OUTSIDE GRANTS INFORMATION Completed Title: Funding Agency: Institution: Project Period: Total Dollars: Direct Cost: Role:

Development of bioactive polymeric meshes to reduce complications of hernia repair surgery Nebraska Research Initiative 2014 - 2016 $100,000 $0 Co-Investigator (David Oupicky)

Title: Funding Agency: Institution: Project Period: Total Dollars: Direct Cost: Role:

Development of Porcine Cancer Models UNMC/Buffett Cancer Center

Title: Funding Agency: Institution: Project Period: Total Dollars: Direct Cost: Role:

Efficacy Of A Hemostatic Bandage Embedded With Recombinant Factors University of Nebraska - Lincoln

Title: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

Regulation of Fibroblast Survival in the Collagen Matrix VHA (Advanced Research Career Development Award) 2001 - 2004 $0 $0 Principal Investigator

Title: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

Repair of Large Hiatal Hernia With Polytetrafluoroethylene W.L. Gore and Associates, Inc. 1996 - 1998 $54,000 $0 Co-Investigator (Constantine T. Frantzides)

2014 - 2015 $50,000 $0 Principal Investigator

2007 - 2010 $150,000 $0 Subcontractor

Title: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

Use of Ketorolac in Postoperative Ileus in Humans Roche Inc. 1992 - 1993 $5,000 $0 Co-Investigator (Robert E. Condon)

Title: Funding Agency: Project Period: Total Dollars: Direct Cost: Role:

Urinary Excretion of Adenosine in Patients Receiving Amphotericin B Squibb Pharmaceutical, Inc. 1992 - 1992 $5,000 $0 Co-Investigator (Robert E. Condon)

PATENTS 1 2 3

Self-closing trocar for minimally invasive surgery. 01/19/2007. Right-angle harmonic scalpel for minimally invasive surgery. 01/23/2007. Daily Diet Score. (Trademark in Supplemental Reg.) 02/27/2007.

OTHER APPOINTMENTS AND POSITIONS 1999 - 2011 2003 - Present 2014 - Present

Moderator, Morbidity & Mortality Conference, Omaha VA Medical Center, Omaha, NE, United States Member, Graduate Faculty, UNMC, Omaha, NE, United States Member, Core Faculty, UNMC, Omaha, NE

CONSULTING POSITIONS Other Present Present Present Present Present Present Present Present Present Present Present

Reviewer, Hernia Reviewer, Surgery Reviewer, Annals of Surgery Reviewer, Surgical Endoscopy Reviewer, Archives of Surgery Reviewer, American Journal of Surgery Reviewer, Biomed Central Research Notes Reviewer, Wound Repair and Regeneration Reviewer, Journal of Biological Chemistry Reviewer, In Vitro Cellular & Developmental Biology Reviewer, International Journal of Medical Robotics and Computer Assisted Surgery

HONORS AND AWARDS

1980 1980-1984 1982 1983 1983, 1984 1984 1984 1984 1986 1993 1995 1997 1998 2001 2001 2004 2007 2008 2008 2013 2014

Academic Scholarship, College of Wooster Dean's List, College of Wooster Joseph Albertus Culler Prize in Physics, College of Wooster Francis and Elizabeth Twinem Scholarship, College of Wooster Summer Research Scholarship, College of Wooster Departmental Honors (Chemistry), College of Wooster William Z. Bennett Prize in Chemistry, College of Wooster Graduation with Honors, College of Wooster Summer Research Grant, Case Western Reserve University Travel Grant Recipient, American Society of Colorectal Surgeons Resident Achievement Award, Society of Laparoendoscopic Surgeons Competent Toastmaster Award, Toastmasters International Grassi Prize Finalist, Collegium Internationale Chirurgiae Digestivae Mentored Clinical Scientist Development Award, National Institutes of Health Advanced Research Career Development Award, Veterans Health Administration Travel Scholarship, American Society of Clinical Investigation Traveling Fellowship to Germany, American College of Surgeons Faculty Special Achievement Award, University of Nebraska New Invention Notification Award, UNeMed Corporation New Investigator Award, University of Nebraska Medical Center New Invention Notification Award, UNeMed Corporation

MEMBERSHIPS AND OFFICES IN PROFESSIONAL SOCIETIES Present Present Present Present Present Present Present Present Present Present Present Present Present Present Present

Member, Sigma XI Member, Phi Beta Kappa Member, American Hernia Society Member, The Wound Healing Society Member, Association of VA Surgeons Fellow, American College of Surgeons Member, Central Surgical Association Member, Society of University Surgeons Member, American Society for Cell Biology Member, American Society for Microbiology Member, Society of Investigative Dermatology Member, Society of Laparoendoscopic Surgeons Member, The Association for Academic Surgery Member, American Association for the Advancement of Science Member, Society of American Gastrointestinal Endoscopic Surgeons

COMMITTEE ASSIGNMENTS Departmental 2011 - 2012

Member, Promotion and Tenure Committee, UNMC Department of

Surgery Local/Regional 2001 - 2006 2003 - 2008 2005 - 2010 2008 - Present

UNMC 2009 - 2012

Member, Subcommittee of Human Studies, VA Medical Center, Omaha NE Member, Library Committee, VA Medical Center, Omaha NE Member, Peer Review Committee, VA Medical Center, Omaha NE Member, Research and Development Committee, VA Medical Center, Omaha NE

Member, Steering Committee for Regenerative Medicine, UNMC

PRESENTATIONS 1. 2. 3.

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Carlson MA; Andorn AC; Piletz JE. [3H]Clonidine Binds to Multiple High Affinity Sites in Human Prefrontal Cortex. Society for Neuroscience; 1985 October. Dallas, TX Carlson MA. The Nephrotoxicity of Amphotericin B. Surgical Grand Rounds; 1992 August. Medical College of Wisconsin, Milwaukee WI Carlson MA; Ludwig KA; Cowles VE; Frantzides CT; Condon RE. The Effect of Propranolol on Colonic Myoelectric Activity in the Postoperative Period. American Motility Society Biennial Symposium; 1992 September. Lake Tahoe, CA Carlson MA. Selective Use of Intraoperative Cholangiograms in Laparoscopic Cholecystectomy. Collegium Internationale Chirurgiae Digestivae; 1992 September. Athens, Greece Carlson MA. Effect of Propranolol on Human Myoelectric Activity. American College of Surgeons Clinical Congress; 1992 October. New Orleans, LA Carlson MA. Antibiotic Prophylaxis in Surgery. Surgical Grand Rounds, Sinai Samaritan Medical Center; 1992 December. Milwaukee, WI Carlson MA. Urinary Excretion of Adenosine in Patients Receiving Amphotericin B. Medical College of Wisconsin Clinic Day; 1993 March. Milwaukee, WI Carlson MA. Urinary Excretion of Adenosine in Patients Receiving Amphotericin B. Milwaukee Academy of Surgery, University Club; 1993 March. Milwaukee, WI Carlson MA. Selection of the Surgical Intern. Surgical Grand Rounds, Medical College of Wisconsin; 1993 June. Milwaukee, WI Carlson MA. A comparison of American and English surgical training. Surgical Grand Rounds; 1993 October. Royal Devon and Exeter Hospital, Exeter England Carlson MA. Ventral Hernia and Other Complications of 1000 Midline Wounds. Western Surgical Association; 1993 November. Seattle, WA Carlson MA. Selective Use of Intraoperative Cholangiograms in Laparoscopic Cholecystectomy. Surgical Morbidity and Mortality, St Joseph's Hospital; 1993 December. Milwaukee, WI Carlson MA. Complications of Midline Incisions. Surgical Morbidity and Mortality, St Joseph_s Hospital; 1993 December. Milwaukee, WI Carlson MA. The Use of Propranolol in Postoperative Ileus in Humans. Medical College of Wisconsin; 1994 February. Milwaukee, WI

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Carlson MA. Complications of Midline Incisions. Surgical Grand Rounds, Medical College of Wisconsin; 1994 February. Milwaukee, WI Carlson MA. Complications of Midline Incisions. Milwaukee Academy of Surgery, University Club; 1994 March. Milwaukee, WI Carlson MA. Polyglyconate (Maxon) vs. Nylon in the Closure of the Vertical Midline Wound. Wisconsin Surgical Association; 1994 April. Milwaukee, WI Carlson MA. Complications of Midline Incisions. Medical College of Wisconsin Clinic Day; 1994 April. Milwaukee, WI Carlson MA. Pathophysiology of Pneumoperitoneum. Surgical Grand Rounds, Medical College of Wisconsin; 1994 October. Milwaukee, WI Carlson MA. Overview of laparoscopic surgery. Winter Refresher Course for Family Physicians, Pfister Hotel; 1995 February. Milwaukee, WI Carlson MA. Resolution of Postoperative Ileus in Laparoscopic Vs. Open Colectomy. Medical College of Wisconsin Clinic Day; 1995 April. Milwaukee, WI Carlson MA. Resolution of Postoperative Ileus in Laparoscopic Vs. Open Colectomy. International American Gastroenterological Association/Singapore Gastroenterological Meeting; 1995 September. Singapore, Republic of Singapore Carlson MA. Complications of midline incisions. Department of Surgery Grand Rounds, Bay Pines VA Medical Center; 1995 September. St. Petersburg, FL Carlson MA; Grinnell F. Apoptosis in fibroblasts: development of in vitro and in situ models. Gordon Research Conference (Cell Death); 1997 July. New London, NH Carlson MA. Acute wound failure: incidence and pathophysiology. Absorbable versus permanent sutures for laparotomy closure. Symposium Suvretta II_Abdominal Wall: Function, Defects, and Repair; 1998 March. St. Moritz, Switzerland Carlson MA. Laparoscopic Prosthetic Reinforcement of Hiatal Herniorrhaphy. Collegium Internationale Chirurgiae Digestivae; 1998 September. Madrid, Spain Carlson MA. Management of Intrathoracic Stomach with Polypropylene Mesh Prosthesis Reinforced Hiatus Hernia Repair. Collegium Internationale Chirurgiae Digestivae; 1998 September. Madrid, Spain Carlson MA. Fibroblasts in a Mechanically Stressed Matrix Undergo Apoptosis After Stress Removal. American College of Surgeons Surgical Forum; 1998 October. Orlando, FL Carlson MA. An investigation of fibroblast regression and a review of acute wound failure. Department of Surgery Research Conference, Ohio State University Medical Center; 1998 December. Columbus, OH Carlson MA. Wound failure. Hernia Repair 1999/American Hernia Society; 1999 February. Las Vegas, NV Carlson MA. Granulation Tissue Apoptosis Induced by a Musculocutaneous Flap. American College of Surgeons, Nebraska Chapter; 2000 May. Omaha, NE Carlson MA. Granulation Tissue Apoptosis Induced by a Musculocutaneous Flap. Association for Academic Surgery; 2000 November. Tampa, FL Carlson MA. Application of a Musculocutaneous Flap Over a Wound Inhibits the Actin Cytoskeleton of the Wound Cells. Association of VA Surgeons; 2001 May. Atlanta, GA Carlson MA. Loss of Extracellular Matrix Anchorage Results in FAK Dephosphorylation and Apoptosis in Fibroblasts. American College of Surgeons Surgical Forum; 2001

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October. New Orleans, LA Carlson MA; Thompson JS. Application of a musculocutaneous flap over a wound inhibits the actin cytoskeleton of the wound cells. Association of VA Surgeons meeting; 2001 May. Atlanta, GA Carlson MA; Lewis RE; Longaker MT; Thompson JS. Loss of extracellular matrix anchorage results in FAK dephosphorylation and apoptosis in fibroblasts. American College of Surgeons; 2001 Oct. New Orleans, LA Carlson MA. Wound Splinting Regulates Granulation Tissue Survival. Association of VA Surgeons; 2002 April. Houston, TX Carlson MA. The fibroblast-populated collagen matrix models granulation tissue. Wound Healing Society; 2002 May. Baltimore, MD Carlson MA. Complications and Results of Minimally Invasive Antireflux Procedures. GERD and Barrett_s Esophagus_An International Symposium; 2002 September. St. Gallen, Switzerland Carlson MA; Lewis RE; Longaker MT; Thompson JS. RNA Interference of FAK in Primary Dermal Fibroblasts. Association for Academic Surgery (AAS); 2002 November. Boston, MA Carlson MA; Thompson JS; Longaker MT. Wound splinting regulates granulation tissue survival. Association of VA Surgeons meeting; 2002 Apr. Houston, TX Carlson MA; Longaker MT; Thompson JS. Poster Presentation: The fibroblast populated matrix models the response of granulation tissue to disruption of wound anchorage. Wound Healing Society; 2002 May. Baltimore, MD Carlson MA. Diaphragmatic Herniorrhaphy with Prosthetic Mesh. Symposium Suvretta III_Use of Mesh Prosthesis in Abdominal Wall Hernia Repair; 2003 January. St. Moritz, Switzerland Carlson MA. FAK regulates survival in the fibroblast-populated collagen matrix. Wound Healing Society; 2003 May. Seattle, WA Carlson MA. Detachment-induced apoptosis in the fibroblast-populated collagen matrix is modulated by p53. American College of Surgeons Surgical Forum; 2003 October. Chicago, IL Carlson MA; Longaker MT; Thompson JS. Wound splinting modulates wound cell survival. Association for Academic Surgery (AAS); 2003 November. Sacramento, CA Carlson MA; Lewis RE; Longaker MT; Thompson JS. Detachment-induced apoptosis in the fibroblast populated collagen matrix is modulated by p53. American College of Surgeons meeting; 2003 Oct. Chicago, IL Carlson MA. Signaling pathways regulated by stress-release of the fibroblast-populated collagen matrix. Society of University Surgeons; 2004 February. St. Louis, MO Carlson MA. Interferon-y is a putative granulation tissue regression factor. Association of VA Surgeons; 2004 April. Richmond, VA Madan AK; Frantzides CT; Tebbitt CL; Park W; Dujovny N; Carlson MA. Randomized trial of training methods for laparoscopic skills. Society of American Gastrointestinal Endoscopic Surgeons (SAGES); 2004 April. Denver, CO Carlson MA. Variable p53 response in a three-dimensional matrix. Wound Healing Society; 2004 May. Atlanta, GA Carlson MA; Moore RE; Madan AK; Frantzides CT. NASH risk factors in bariatric patients. Society of Surgery of the Alimentary Tract (SSAT); 2004 May. New Orleans,

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LA Carlson MA. Wound matrix attachment regulates actin in cells of the granulation tissue. Association for Academic Surgery; 2004 November. Houston, TX Carlson MA; Longaker MT; Thompson JS. Signaling pathways regulated by stress-release of the fibroblast-populated collagen matrix. Society of University Surgeons meeting; 2004 Feb. St. Louis, MO Carlson MA. Update on Wound Healing and Regeneration. Department of Surgery Grand Rounds, Medical College of Wisconsin; 2005 April. Milwaukee, WI Zeni TM; Carlson MA; Zografakis JG; Frantzides CT. Laparoscopic redo Nissen fundoplication. Society of American Gastrointestinal Endoscopic Surgeons (SAGES); 2005 April. Ft. Lauderdale, FL Carlson MA. Proteomic and genomic analysis of a granulation tissue regression model. American Society of Clinical Investigation; 2005 April. Chicago, IL Carlson MA. Worldwide Analysis of Laparoscopic Treatment of GERD. 7th Pan-Hellenic Congress of Laparoendoscopic Surgery; 2005 May. Ioannina, Greece Carlson MA. Technical Factors That Influence Incisional Herniation. Symposium Suvretta IV - Recurrent Hernia; 2006 February. St. Moritz, Switzerland Carlson MA. Technical Factors That Influence Incisional Herniation. American College of Surgeons Postgraduate Course; 2006 October. Chicago, IL Carlson MA. A review of 6,266 published cases of minimally invasive ventral herniorrhaphy. American Hernia Society; 2007 March. Hollywood, FL Carlson MA. Complications and Results of Minimally Invasive Incisional Herniorrhaphy. 124th Congress of the German Surgical Society; 2007 May. Munich, Germany Carlson MA. Report of the 2007 American College of Surgeons Traveling Fellow to Germany. American College of Surgeons 93rd Annual Clinical Congress; 2007 October. New Orleans, LA Carlson MA. Radiation Injury From A Nuclear Accident Or Terrorist Attack. Omaha VA Medical Center Research Conference; 2008 May. Omaha, NE Frantzides CT; Keshavarzian A; Roberts J; Meiselman M; Carlson MA. Laparoscopic transgastric esophageal mucosal resection for high grade dysplasia. American College of Surgeons Clinical Congress; 2009 October. Chicago, IL Krause CM; Carlson MA. Differential contraction in fibroblast-populated 3D collagen matrices made with type I vs. type III collagen. Gordon Research Conference (Signal Transduction By Engineered Extracellular Matrices); 2010 June. Biddeford, ME Carlson MA. Television interview with KETV on aspects of the Liquid Bandage project. 2010 Oct 21. Omaha, NE Carlson MA. Omaha World Herald newspaper article, _UNMC bandage may save lives_. 2010 Oct 21. Omaha, NE Carlson MA. A Totally Recombinant Factor XIII-Supplemented Fibrin Sealant. Society of University Surgeons/Academic Surgical Congress; 2011 February. Huntington Beach, CA Carlson MA; Velander WH; Larsen G; Calcaterra J; Pipinos II; Johanning JM; Krause CM; Noriega S; Spretz R; Burgess WH. Development of Novel Hemostatic Devices in Swine Hemorrhage Models. American Association of Laboratory Animal Science, District 6; 2011 April. Omaha, NE Velander WH; Calcaterra J; Spretz R; Noriega S; Larsen G; Carlson MA; Pipinos II;

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Johanning JM. Nanofibrous PLA Mesh is Wound Adherent and Hemostatic in Pig Liver Resection Model. Society for Biomaterials; 2011 April. Orlando, FL Carlson MA; Velander WH; Larsen G; Calcaterra J; Pipinos II; Johanning JM; Krause CM; Noriega S; Spretz R; Burgess WH. Development of Novel Hemostatic Devices in Swine Hemorrhage Models. VA Research Week; 2011 May. Omaha, NE Velander WH; Calcaterra J; Spretz R; Noriega S; Larsen G; Carlson MA; Pipinos II; Johanning JM. Bioengineering hemostasis using human fibrinogen sealants in swine surgical models. Swine in Biomedical Research Conference; 2011 July. Chicago, IL Carlson MA; Calcaterra J; Noriega S; Spretz R; Larsen G; Pipinos II; Johanning JM; Velander WH. Treatment of Major Hemorrhage with Recombinant Resorbable Fibrin Sealant Bandages. American College of Surgeons Surgical Forum; 2011 October. San Francisco, CA Carlson MA. NET radio interview, _Researchers seek better approach to healing wounds_. 2011 Sep 2. Lincoln, NE Carlson MA. Appearance in online science program, "Growing Skin". 2011 Nov 15 Carlson MA; Eudy JD; Smith LM. Gene Networks Involved With Mechanoregulation Of Cell Population In The Fibroblast- Populated 3D Collagen Matrix. Academic Surgical Congress; 2012 February. Las Vegas, NV Carlson MA. Hemostasis & Healing. Omaha VA Research Conference; 2012 April. Omaha, NE Doyle DA; Chao J; Heimann D; Pena T; Hansen C; Carlson MA. Effect Of An NF-kB Inhibitor On The Cell Population In The Fibroblast-Populated Collagen Matrix. Academic Surgical Congress; 2013 February. New Orleans, LA Carlson MA. Medical Subject Headings: Hemostasis, Wound Healing, Regenerative Medicine. Department of Genetics, Cell Biology, and Anatomy Research Conference; 2013 February. Omaha, NE Carlson MA. The Use of Swine in Biomedical Research. West Omaha Rotary Club; 2013 May. Omaha, NE Ismail A; Calcaterra J; Carlson MA; Burgess WH; Velander WH. Fibrinogen/Fibronectin complex forms strong fibrin polymer and is chemotactic to fibroblasts and endothelial cells in vitro. 2013 Biomedical Engineering Society Annual Meeting; 2013 September. Seattle, WA Johanning JM; Carlson MA; Bailey T; Huben NB; Seevers GA; Bockman T; Goede M; Lynch TG. Implementation And Validation Of A Bedside Frailty Index To Improve Surgical Decision-Making. 2013 American College of Surgeons Clinical Congress; 2013 October. Washington, DC Carlson MA. Development Of A Porcine Cancer Model: A Proposal. 2013 06. UNL Institute of Agriculture and Natural Resources, Lincoln, NE Yanala UR; Reidelberger RD; Thompson JS; Carlson MA. Effect of 50% enterectomy on nutritional parameters in lean and obese rats. 2014 Clinical Nutrition Week; 2014 January. Savannah, GA Guenther TM; Chao J; Heimann D; Hansen C; Carlson MA. Disruption of Nuclear Factor_kappa-B Signaling in the Fibroblast-Populated Collagen Matrix. 2014 Academic Surgical Congress; 2014 February. San Diego, CA Yanala UR; Johanning JM; Pipinos II; Velander WH; Carlson MA. Development of a porcine model of severe noncompressible truncal hemorrhage. 2014 Academic Surgical

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Congress; 2014 February. San Diego, CA Yanala UR; Johanning JM; Pipinos II; Velander WH; Carlson MA. Development of a Model of Internal Bleeding [poster]. 2014 Omaha VA Medical Center Research Week; 2014 05. Omaha, NE Carlson MA; Yanala UR; Johanning JM; Pipinos II; Velander WH. Development of a porcine model of severe noncompressible truncal hemorrhage [poster]. 2014 Swine in Biomedical Research Conference; 2014 07. Raleigh, NC Xie J; Carlson MA; Jiang J. Microskin-seeded Electrospun Nanofiber Scaffolds for Skin Regeneration. 3rd International Conference on Electrospinning; 2014 08. San Francisco, CA Carlson MA. Overview of Porcine Biomedical Research in Omaha. Animal Genetics Seminar; 2014 10. UNL Department of Animal Sciences, Lincoln, NE Carlson MA; Reidelberger R; Thompson JS. Poster Presentation: Effect of 50% enterectomy on nutritional parameters in lean and obese rats. Nutrition Week; 2014 Jan. Savannah, GA Tanner TN; Simorov A; Lomelin D; Lackner R; Trujillo K; Oleynikov D; Carlson M. Minimally Invasive Versus Open Esophagectomy: Short-Term Outcomes from a National Database and a Local Series. Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) meeting; 2014 04. Salt Lake City, UT Yanala UR; Noriega S; Spretz R; Ragusa J; Nunez L; Larsen G; Carlson MA. Synthetic Resorbable vs. Cellulose Bandage for Minor Hemorrhage in a Porcine Model. 2015 Academic Surgical Congress; 2015 Feb. Las Vegas, NV Yanala UR; Johanning JM; Pipinos II; Larsen G; Velander WH; Carlson MA. Effect Of Crystalloid Infusion Rate In A Noncompressible Hemorrhage Model. 2015 Central Surgical Association Meeting; 2015 Mar. Chicago, IL Yanala UR; Reidelberger RD; Thompson JS; Carlson MA. Effect of 75% Intestinal Resection on Body Composition in Lean vs. Obese Rats. 2015 American College of Surgeons Clinical Congress; 2015 October. Chicago, IL

PUBLICATIONS

A. ARTICLES PUBLISHED IN SCHOLARLY JOURNALS 1. 2. 3.

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Johnson LK, Haynes LW, Carlson MA, Fortnum HA, Gorgas DL. Alarm substances of the stingless bee, Trigona silvestriana. Journal of Chemical Ecology. 11 : 409-16. 1985 Carlson MA, Andorn AC. [3H]clonidine binds at multiple high affinity states in human prefrontal cortex. European Journal of Pharmacology. 123 : 73-78. 1986 Andorn AC, Carlson MA, Gilkeson RC. Specific [3H]UK14,304 binding in human cortex occurs at multiple high affinity states with alpha2-adrenergic selectivity and differing affinities for GTP. Life Sciences. 43 : 1805-1812. 1988 Carlson MA; Ludwig KA; Cowles VE; Frantzides CT; Condon RE. Effect of propranolol on human myoelectric activity. Surgical forum. 1992; Vol. 43: p. 155-157. 0071-8041 Ludwig KA, Frantzides CT, Carlson MA, Grade KL. Myoelectric motility patterns following open versus laparoscopic cholecystectomy. Journal of Laparoendoscopic Surgery. 3 : 461-466. 1993

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Ludwig KA, Carlson MA, Condon RE. Prophylactic antibiotics in surgery. Annual Review of Medicine. 44 : 385-393. 1993 Carlson MA, Ludwig KA, Frantzides CT, Cattey RP, Henry LG, Walker AP, Schulte WJ, Wilson SD. Routine or selective intraoperative cholangiography in laparoscopic cholecystectomy. Journal of Laparoendoscopic Surgery. 3 : 27-33. 1993 Carlson MA, Condon RE. Nephrotoxicity of amphotericin B. Journal of the American College of Surgeons. 179 : 361-381. 1994 Frantzides CT, Carlson MA. Laparoscopic repair of a penetrating injury to the diaphragm: A case report. Journal of Laparoendoscopic Surgery. 4 : 153-156. 1994 Frantzides CT; Carlson MA; Makris V; Potamitis G; Efthimiou E. The first laparoscopic Nissen fundoplications in Cyprus. Cyprus medical journal. 1995; Vol. 13 (3): p. 12-15 Carlson MA, Ludwig KA, Condon RE. Ventral hernia and other complications of 1,000 midline incisions. Southern Medical Journal. 88 : 450-453. 1995 Frantzides CT, Carlson MA. Laparoscopic versus conventional fundoplication. Journal of Laparoendoscopic Surgery. 5 : 137-143. 1995 Frantzides CT, Carlson MA, Schulte WJ. Laparoscopic gastric bypass in a porcine model. Journal of Laparoendoscopic Surgery. 5 : 97-100. 1995 Carlson MA, Condon RE. Polyglyconate (Maxon®) versus nylon suture in midline abdominal incision closure: A prospective randomized trial. American Surgeon. 61 : 980-983. 1995 Condon RE, Cowles VE, Ferraz AA, Carilli S, Carlson ME, Ludwig K, Tekin E, Ulualp K, Ezberci F, Shoji Y. Human colonic smooth muscle electrical activity during and after recovery from postoperative ileus. American Journal of Physiology - Gastrointestinal and Liver Physiology. 269 : G408-17. 1995 Frantzides CT; Carlson MA. A review of laparoscopic surgery of the colon and rectum. Cyprus medical journal. 1996; Vol. 14: p. 45-49 Frantzides CT; Carlson MA. A review of laparoscopic surgery of the esophagus. Cyprus medical journal. 1996; Vol. 14: p. 16-18 Carlson MA, Frantzides CT. Control of venous hemorrhage during laparoscopic adrenalectomy: A case report. Journal of Laparoendoscopic Surgery. 6 : 349-351. 1996 Frantzides CT, Carlson MA. Laparoscopic jaboulay gastroduodenostomy for gastric outlet obstruction: A case report. Journal of Laparoendoscopic Surgery. 6 : 341-344. 1996 Carlson MA. Acute wound failure. Surgical Clinics of North America. 77 : 607-636. 1997 Carlson MA, Ferraz AA, Condon RE. Urinary adenosine excretion in patents receiving amphotericin B. Surgery. 121 : 190-193. 1997 Frantzides CT, Carlson MA. Minimally invasive ventral herniorrhaphy. Journal of Laparoendoscopic and Advanced Surgical Techniques - Part A. 7 : 117-120. 1997 Frantzides CT, Carlson MA. Laparoscopic highly selective vagotomy. Journal of Laparoendoscopic and Advanced Surgical Techniques - Part A. 7 : 143-146. 1997 Carlson MA, Frantzides CT. Canine intestinal myoelectric activity after open versus laparoscopically assisted right hemicolectomy. American Journal of Surgery. 174 : 79-82. 1997 Frantzides CT, Carlson MA. Prosthetic reinforcement of posterior cruroplasty during laparoscopic hiatal herniorrhaphy. Surgical Endoscopy. 11 : 769-771. 1997 Frantzides CT, Carlson MA. Laparoscopic redo nissen fundoplication. Journal of Laparoendoscopic and Advanced Surgical Techniques - Part A. 7 : 235-239. 1997

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Carlson MA; Zhu M; Abrams JM; Grinnell F. Human fibroblasts in a mechanically stressed matrix undergo apoptosis after stress removal. Surgical forum. 1998; Vol. 49: p. 643-645. 0071-8041 Carlson MA, Condon RE, Ludwig KA, Schulte WJ. Management of intrathoracic stomach with polypropylene mesh prosthesis reinforced transabdominal hiatus hernia repair. Journal of the American College of Surgeons. 187 : 227-230. 1998 Frantzides CT; Carlson MA. Minimally invasive Nissen fundoplication with hernia repair. Hellenic Laparoendoscopic Surgery. 1999; Vol. 2: p. 12-19 Carlson MA, Richards CG, Frantzides CT. Laparoscopic prosthetic reinforcement of hiatal herniorrhaphy. Digestive Surgery. 16 : 407-410. 1999 Grinnell F, Zhu M, Carlson MA, Abrams JM. Release of mechanical tension triggers apoptosis of human fibroblasts in a model of regressing granulation tissue. Experimental Cell Research. 248 : 608-619. 1999 Frantzides CT, Richards CG, Carlson MA. Laparoscopic repair of large hiatal hernia with polytetrafluoroethylene. Surgical Endoscopy. 13 : 906-908. 1999 Frantzides CT, Carlson MA, Pappas C, Gatsoulis N. Laparoscopic repair of a congenital diaphragmatic hernia in an adult. Journal of Laparoendoscopic and Advanced Surgical Techniques - Part A. 10 : 287-290. 2000 Carlson MA. New developments in abdominal wall closure. Chirurg. 71 : 743-753. 2000 Carlson MA; Lewis RE; Longaker MT; Thompson JS. Loss of extracellular matrix anchorage results in FAK dephosphorylation and apoptosis in fibroblasts. Surgical forum. 2001; Vol. 52: p. 547-549. 0071-8041 Carlson MA, Frantzides CT. Complications and results of primary minimally invasive antireflux procedures: A review of 10,735 reported cases. Journal of the American College of Surgeons. 193 : 428-439. 2001 Carlson MA, Horton JW. A primary burn wound does not slow the contraction rate of adjacent excisional wound. Annals of Plastic Surgery. 46 : 36-42. 2001 Carlson MA, Longaker MT, Thompson JS. Granulation tissue regression induced by musculocutaneous advancement flap coverage. Surgery. 131 : 332-337. 2002 Frantzides CT, Madan AK, Carlson MA, Stavropoulos GP. A prospective, randomized trial of laparoscopic polytetrafluoroethylene (PTFE) patch repair vs simple cruroplasty for large hiatal hernia. Archives of Surgery. 137 : 649-652. 2002 Molpus KL, Wedergren JS, Carlson MA. Robotically assisted endoscopic ovarian transposition. JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons. 7 : 59-62. 2003 Carlson MA, Longaker MT, Thompson JS. Wound splinting regulates granulation tissue survival. Journal of Surgical Research. 110 : 304-9. 2003 Frantzides CT, Carlson MA, Madan AK, Stewart ET, Smith C. Selective use of esophageal manometry and 24-hour pH monitoring before laparoscopic fundoplication. Journal of the American College of Surgeons. 197 : 358-364. 2003 Frantzides CT, Moore RE, Carlson MA, Madan AK, Zografakis JG, Keshavarzian A, Smith C. Minimally invasive surgery for achalasia: A 10-year experience. Journal of Gastrointestinal Surgery. 8 : 18-23. 2004 Frantzides CT, Carlson MA, Moore RE, Zografakis JG, Madan AK, Puumala S, Keshavarzian A. Effect of body mass index on nonalcoholic fatty liver disease in patients undergoing minimally invasive bariatric surgery. Journal of Gastrointestinal Surgery. 8 :

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849-855. 2004 Carlson MA, Longaker MT. The fibroblast-populated collagen matrix as a model of wound healing: A review of the evidence. Wound Repair and Regeneration. 12 : 134-147. 2004 Carlson MA, Thompson JS. Wound splinting modulates granulation tissue proliferation. Matrix Biology. 23 : 243-250. 2004 Carlson MA, Longaker MT, Thompson JS. Modulation of FAK, Akt, and p53 by stress release of the fibroblast-populated collagen matrix. Journal of Surgical Research. 120 : 171-177. 2004 Carlson MA, Longaker MT, Thompson JS. Modulation of FAK, Akt, and p53 by stress release of the fibroblast-populated collagen matrix. The Journal of surgical research. 121 : 151. 2004 Frantzides CT, Carlson MA, Zografakis JG, Madan AK, Moore RE. Minimally invasive incisional herniorrhaphy: A review of 208 cases. Surgical Endoscopy and Other Interventional Techniques. 18 : 1488-1491. 2004 Frantzides CT, Madan AK, Moore RE, Zografakis JG, Carlson MA, Keshavarzian A. Laparoscopic transgastric esophageal mucosal resection for high-grade dysplasia. Journal of Laparoendoscopic and Advanced Surgical Techniques - Part A. 14 : 261-265. 2004 Carlson MA, Frantzides CT. Laparoscopic repair of paraesophageal hiatal hernia [2]. Surgical Endoscopy and Other Interventional Techniques. 18 : 1821. 2004 Carlson MA, Thompson JS. Wound matrix attachment regulates actin content and organization in cells of the granulation tissue. Wound Repair and Regeneration. 13 : 84-92. 2005 Carlson MA, Frantzides CT. Mesh-reinforced hiatal hernia repair [1]. Surgical Endoscopy and Other Interventional Techniques. 19 : 1423. 2005 Frantzides CT, Carlson MA, Zografakis JG, Moore RE, Zeni T, Madan AK. Postoperative gastrointestinal complaints after laparoscopic Nissen fundoplication. JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons. 10 : 39-42. 2006 Eichler MJ, Carlson MA. Modeling dermal granulation tissue with the linear fibroblast-populated collagen matrix: A comparison with the round matrix model. Journal of Dermatological Science. 41 : 97-108. 2006 Granderath FA, Carlson MA, Champion JK, Szold A, Basso N, Pointner R, Frantzides CT. Prosthetic closure of the esophageal hiatus in large hiatal hernia repair and laparoscopic antireflux surgery. Surgical Endoscopy and Other Interventional Techniques. 20 : 367-379. 2006 Carlson MA. Technical note: Assay of cell quantity in the fibroblast-populated collagen matrix with a tetrazolium reagent. European Cells and Materials. 12 : 44-48. 2006 Carlson MA. Report of the 2007 American College of Surgeons traveling fellow to Germany. 2007; Vol. 4: p. 383-386 Carlson MA. Report of the 2007 American College of Surgeons traveling fellow to Germany. Bulletin of the American College of Surgeons. 2007; Vol. 92: p. 40-47. 0002-8045 M.P. Simons; T.S. De Vries Reilingh; O.R. Buyne; R.P. Bleichrodt; C.T. Frantzides; L.E. Laguna; M.A. Carlson. How to create a recurrence after incisional hernia repair. Recurrent Hernia: Prevention and Treatment. 163-178. 2007

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Carlson MA, Petersen A. Technique for the insertion of large mesh during minimally invasive incisional herniorrhaphy. Surgical Endoscopy and Other Interventional Techniques. 21 : 1243-1244. 2007 Carlson MA, Prall AK, Gums JJ. RNA interference in human foreskin fibroblasts within the three-dimensional collagen matrix. Molecular and Cellular Biochemistry. 306 : 123-132. 2007 Carlson MA, Frantzides CT, Shostrom VK, Laguna LE. Minimally invasive ventral herniorrhaphy: An analysis of 6,266 published cases. Hernia. 12 : 9-22. 2008 Frantzides CT; Madan AK; Carlson MA. Laparoscopic colectomy in an academic U.S. center. Hellenic Journal of Surgery. 2009; Vol. 81: p. 80-86 Foda M, Carlson MA. Enterocutaneous fistula associated with ePTFE mesh: Case report and review of the literature. Hernia. 13 : 323-326. 2009 Carlson MA, Prall AK, Gums JJ, Lesiak A, Shostrom VK. Biologic variability of human foreskin fibroblasts in 2D and 3D culture: Implications for a wound healing model. BMC Research Notes. 2 : 229. 2009 Frantzides CT, Madan AK, Carlson MA, Zeni TM, Zografakis JG, Moore RM, Meiselman M, Luu M, Ayiomamitis GD. Laparoscopic revision of failed fundoplication and hiatal herniorraphy. Journal of Laparoendoscopic and Advanced Surgical Techniques. 19 : 135-139. 2009 Carlson MA, Prall AK, Gums JJ, Lesiak A, Shostrom VK. Biologic variability of human foreskin fibroblasts in 2D and 3D culture: implications for a wound healing model. BMC research notes. 2 : 229. 2009 Frantzides CT, Carlson MA, Loizides S, Papafili A, Luu M, Roberts J, Zeni T, Frantzides A. Hiatal hernia repair with mesh: A survey of SAGES members. Surgical Endoscopy and Other Interventional Techniques. 24 : 1017-1024. 2010 Frantzides CT, Carlson MA, Keshavarzian A, Roberts JE. Laparoscopic transgastric esophageal mucosal resection: 4-year minimum follow-up. American Journal of Surgery. 200 : 305-307. 2010 Carlson MA, Chakkalakal D. Tensile properties of the murine ventral vertical midline incision. PLoS ONE. 6 : 2011 Frantzides CT, Carlson MA, Shostrom VK, Roberts J, Stavropoulos G, Ayiomamitis G, Frantzides A. A survey of dumping symptomatology after gastric bypass with or without lesser omental transection. Obesity Surgery. 21 : 186-193. 2011 Mark A. Carlson. Research priorities in bariatric surgery: Misplaced emphasis on innovation?. Annals of Surgery. 2013 Calcaterra J, Van Cott KE, Butler SP, Gil GC, Germano M, van Veen HA, Nelson K, Forsberg EJ, Carlson MA, Velander WH. Recombinant human fibrinogen that produces thick fibrin fibers with increased wound adhesion and clot density. Biomacromolecules. 14 : 169-78. 2013 Mark A. Carlson. Comment on "Prospective randomized clinical trial comparing laparoscopic cholecystectomy and hybrid natural orifice transluminal endoscopic surgery (NOTES) (NCT00835250)" (doi:10.1007/s00464-012-2359-4). Surgical Endoscopy. 1-2. 2013 Carlson MA, Smith LM, Cordes CM, Chao J, Eudy JD. Attachment-regulated signaling networks in the fibroblast-populated 3D collagen matrix. Scientific Reports. 3 : 1880. 2013

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Carlson MA, Calcaterra J, Johanning JM, Pipinos II, Cordes CM, Velander WH. A totally recombinant human fibrin Sealant. Journal of Surgical Research. 187 : 334-42. 2013 Carlson MA. Comment on "prospective randomized clinical trial comparing laparoscopic cholecystectomy and hybrid natural orifice transluminal endoscopic surgery (NOTES) (NCT00835250)" (doi:10.1007/s00464-012-2359-4). Surgical Endoscopy and Other Interventional Techniques. 27 : 3929-30. 2013 Chao C; Pena T; Heimann DG; Hansen C; Doyle DA; Carlson MA. Expression of green fluorescent protein in human foreskin fibroblasts for use in 2D and 3D culture models. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 2014; Vol. 22: p. 134-140. 1067-1927 Yanala UR; Johanning JM; Pipinos II; Larsen G; Velander WH; Carlson MA. Development of a fatal noncompressible truncal hemorrhage model with combined hepatic and portal venous injury in normothermic normovolemic Swine. PLoS ONE. 2014 Chao J, Peña T, Heimann DG, Hansen C, Doyle DA, Yanala UR, Guenther TM, Carlson MA. Expression of green fluorescent protein in human foreskin fibroblasts for use in 2D and 3D culture models. Wound Repair and Regeneration. 22 : 134-40. 2014 Mark A. Carlson. Reply to letter: "from bariatric to metabolic surgery: New concepts on the rise". Annals of Surgery. 2014 Ujwal R. Yanala; Jason M. Johanning; Iraklis I. Pipinos; Gustavo Larsen; William H. Velander; Mark A. Carlson. Development of a fatal noncompressible truncal hemorrhage model with combined hepatic and portal venous injury in normothermic normovolemic swine. PLoS ONE. 9 : 2014 Carlson MA, Calcaterra J, Johanning JM, Pipinos II, Cordes CM, Velander WH. A totally recombinant human fibrin sealant. Journal of Surgical Research. 187 : 334-42. 2014 Mark A. Carlson. Research priorities in bariatric surgery: Misplaced emphasis on innovation?. Annals of Surgery. 261 : e58-e59. 2015 Mark A. Carlson. Reply to letter: From bariatric to metabolic surgery: New concepts on the rise. Annals of Surgery. 262 : e80. 2015 Ujwal R. Yanala; Roger D. Reidelberger; Jon S. Thompson; Valerie K. Shostrom; Mark A. Carlson. Effect of proximal versus distal 50% enterectomy on nutritional parameters in rats preconditioned with a high-fat diet or regular chow. Scientific Reports. 5 : 2015 Jie Chao; Xiaoniu Dai; Tiffany Peña; David A. Doyle; Timothy M. Guenther; Mark A. Carlson. MCPIP1 regulates fibroblast migration in 3-D collagen matrices downstream of MAP kinases and NF-κB. Journal of Investigative Dermatology. 135 : 2944-2954. 2015 jiang, jiang; Carlson MA; Teusink MJ; macewan, matthew; xie, jingwei; Wang, Hongjun. Expanding Two-dimensional Electrospun Nanofiber Membranes in the Third Dimension By a Modified Gas-foaming Technique. ACS Biomaterials Science & Engineering. 2015 Aug Yanala UR; Reidelberger RD; Thompson JS; Shostram VK; Carlson MA. Effect of proximal versus distal 50% enterectomy on nutritional parameters in rats preconditioned with a high-fat diet or regular diet. Scientific reports. 2015 Nov; Vol. 5: p. 17331

B. ARTICLES ACCEPTED FOR PUBLICATION IN SCHOLARLY JOURNALS

Not Applicable C. ARTICLES SUBMITTED FOR PUBLICATION IN SCHOLARLY JOURNALS Not Applicable D. BOOKS PUBLISHED, IN PREPARATION, SUBMITTED OR IN PRESS 1. 2.

Frantzides CT; Carlson MA. Atlas of Minimally Invasive Surgery. Saunders Elsevier; 2009 Frantzides CT; Carlson MA. Video Atlas of Advanced Minimally Invasive Surgery. Saunders Elsevier; 2013

E. CHAPTERS IN BOOKS 1. 2. 3. 4.

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Carlson MA; Condon RE. Manual of Surgical Therapeutics. Little, Brown and Company; 1992. Minor Surgical Techniques Carlson MA; Frantzides CT. Laparoscopic and Thoracoscopic Surgery. Mosby; 1995. Complications of Laparoscopic Procedures Frantzides CT; Carlson MA. Laparoscopic and Thoracoscopic Surgery. Mosby; 1995. The Future of Laparoscopic Surgery Carlson MA; Frantzides CT. Proceedings of the 15th World Congress of Collegium Internationale Chirurgiae Digestivae. Monduzzi Editore; 1996. Minimally Invasive Surgery of the Colon Carlson MA; Frantzides, CT. Proceedings of the 15th World Congress of Collegium Internationale Chirurgiae Digestivae. Monduzzi Editore; 1996. Minimally Invasive Surgery of the Esophagus Carlson MA; Condon RE. Manual of Surgical Therapeutics. Little, Brown and Company; 1996. Minor Surgical Techniques Carlson MA. Incisional Hernia. Springer; 1999. Acute Wound Failure Carlson MA. Incisional Hernia. Springer; 1999. Absorbable Versus Nonabsorbable Suture For Laparotomy Closure Carlson MA. Current Surgical Therapy. Mosby, Inc; 2001. Abdominal Wound Dehiscence Frantzides CT; Carlson MA. Mastery of Surgery. Lippincott Williams & Wilkins; 2001. Paraesophageal Herniation Carlson MA. Meshes: Benefits and Risks. Springer; 2004. Diaphragmatic Herniorrhaphy with Prosthetic Mesh Carlson MA. Basic Science for Surgical Specialists. W.B. Saunders; 2004. The Cell: Structure and Function Frantzides CT; Carlson MA. Laparoscopic Surgery. Paschalides Medical Publishing; 2005. Laparoscopic Treatment of Gastroesophageal Reflux and Hiatal Hernia Granderath FA; Frantzides CT; Carlson MA. Gastroesophageal Reflux Disease: Principles Of Disease, Diagnosis And Treatment. Springer Wien New York; 2006. Hiatal Closure_New Trends In Laparoscopic Antireflux Surgery Carlson MA. Recurrent Hernia: Prevention and Treatment. Springer; 2007. Technical

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Factors That Influence Incisional Herniation Frantzides CT; Carlson MA. Recurrent Hernia: Prevention and Treatment. Springer; 2007. Technical Factors Predisposing To Recurrence After Minimally Invasive Incisional Herniorrhaphy Frantzides CT; Carlson MA. Atlas of Minimally Invasive Surgery. Saunders Elsevier; 2009. Laparoscopic Nissen Fundoplication Frantzides CT; Carlson MA; Granderath FA. Atlas of Minimally Invasive Surgery. Saunders Elsevier; 2009. Laparoscopic Hiatal Herniorrhaphy Frantzides CT; Carlson MA; Madan AK. Atlas of Minimally Invasive Surgery. Saunders Elsevier; 2009. Minimally Invasive Left Hemicolectomy Carlson MA. Atlas of Minimally Invasive Surgery. Saunders Elsevier; 2009. Laparoscopic Cholecystectomy Frantzides CT; Carlson MA. Atlas of Minimally Invasive Surgery. Saunders Elsevier; 2009. Laparoscopic Transabdominal Inguinal Herniorrhaphy Frantzides CT; Carlson MA. Atlas of Minimally Invasive Surgery. Saunders Elsevier; 2009. Minimally Invasive Incisional and Ventral Herniorrhaphy Frantzides CT; Carlson MA. Atlas of Minimally Invasive Surgery. Saunders Elsevier; 2009. Minimally Invasive Transverse Colectomy Madan AK; Carlson MA; Frantzides CT. Atlas of Minimally Invasive Surgery. Saunders Elsevier; 2009. Laparoscopic Repair of Diaphragmatic Hernia Not Involving the Hiatus Frantzides CT; Carlson MA; Welle S. Textbook of General Surgery. Gunes Kitabevi; 2012. Minimally Invasive Surgical Therapy for Gastroesophageal Reflux Disease and Hiatal Hernia Carlson MA. Video Atlas of Advanced Minimally Invasive Surgery. Saunders Elsevier; 2013. Complications of Peritoneal Access Carlson MA. Video Atlas of Advanced Minimally Invasive Surgery. Saunders Elsevier; 2013. Minimally Invasive Low Anterior Resection with Total Mesorectal Excision for Malignancy

F. BOOKS OR JOURNALS EDITED Not Applicable G. ABSTRACTS AND PRELIMINARY COMMUNICATIONS 1.

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Carlson MA. Undergraduate Thesis: Identification and Quantification of Compounds in the Head Extracts of Trigona cilipes, T. pectoralis barrocolorodensis, and T. silvestriana. 1984 Carlson MA; Ludwig KA; Cowles VE; Frantzides CT; Condon RE. The Effect of Propranolol on Human Colonic Myoelectric Activity in the Postoperative Period. Gastroenterology. 1992, Vol. 103: 1382 Ludwig KA; Frantzides CT; Cowles VE; Carlson MA; Condon RE. Cholecystokinin and Gastrin Responses During Postoperative Ileus. Gastroenterology. 1992, Vol. 103: 1382 Ludwig KA; Carlson MA; Frantzides CT. Does Minimally Invasive Surgery Result in a Shorter Period of Postoperative Ileus?. Gastroenterology. 1992, Vol. 103: 1382 Carlson MA; Frantzides CT. Resolution of postoperative ileus in laparoscopic vs open

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colectomy. J Gastroenterol. 1995, Vol. 10: A84 Carlson MA; Ludwig KA; Condon RE. Polypropylene mesh reinforced hiatus hernia repair. Gastroenterology. 1997, Vol. 112: A1434 Carlson MA; Richards CG; Frantzides CT. Laparoscopic prosthetic reinforcement of hiatal herniorrhaphy. Dig Surg. 1998, Vol. 15: 496 Carlson MA; Condon RE. Management of intrathoracic stomach with polypropylene mesh prosthesis reinforced hiatus hernia repair. Dig Surg. 1998, Vol. 15: 589-590 Carlson MA; Horton JW. Effect of burn injury on wound contraction. Wound Rep Regen. 1999, Vol. 7: A291 Carlson MA; Baxter BT. Granulation tissue apoptosis induced by a musculocutaneous flap. J Surg Res. 2000, Vol. 93: 315 Carlson MA; Longaker MT; Thompson JS. The fibroblast-populated matrix models the response of granulation tissue to disruption of wound anchorage. Wound Rep Regen. 2002, Vol. 10: A8 Carlson MA; Lewis RE; Longaker MT; Thompson JS. RNA Interference of FAK in Primary Dermal Fibroblasts. J Surg Res. 2002, Vol. 107: 307-308 Carlson MA; Longaker MT; Thompson JS. FAK regulates survival in the fibroblast-populated collagen matrix. Wound Rep Regen. 2003, Vol. 11: A12 Carlson MA; Lewis RE; Longaker MT; Thompson JS. Detachment-induced apoptosis in the fibroblast-populated collagen matrix is modulated by p53. J Am Coll Surg. 2003, Vol. 197: S55 Carlson MA; Longaker MT; Thompson JS. Wound splinting modulates wound cell proliferation. J Surg Res. 2003, Vol. 114: 306 Carlson MA; Longaker MT. Variable p53 response in a 3D matrix. Wound Rep Regen. 2004, Vol. 12: A6 Carlson MA. Wound matrix attachment regulates actin in cells of the granulation tissue. J Surg Res. 2004, Vol. 121: 306 Frantzides CT; Zeni TM; Zografakis JG; Carlson MA. Laparoscopic redo Nissen fundoplication. Surg Endosc. 2005, Vol. 19: S265 Frantzides CT; Madan AK; Carlson MA; Zeni TM; Zografakis JG; Moore RM; Meiselman M; Placeway L; Luu MB. Laparoscopic revision of failed fundoplication and hiatal herniorrhaphy. Surg Endosc. 2008, Vol. 22: S257 Carlson MA; Velander WH; Pipinos II; Johanning JM; Calcaterra J. A Totally Recombinant Factor XIII-Supplemented Fibrin Sealant. J Surg Res. 2011, Vol. 165: 317 Carlson MA; Eudy JD; Smith LM. Gene networks involved with mechanoregulation of cell population in the fibroblast-populated 3D collagen matrix. J Surg Res. 2012, Vol. 172: 266 Doyle DA; Chao J; Heimann D; Pena T; Hansen C; Carlson MA. Effect Of An NF-kB Inhibitor On The Cell Population In The Fibroblast-Populated Collagen Matrix. J Surg Res. 2013, Vol. 179: 267 Yanala UR; Johanning JM; Pipinos II; Velander WH; Carlson MA. Development of a porcine model of severe noncompressible truncal hemorrhage. J Surg Res. 2014, Vol. 186: 510 Guenther TM; Chao J; Heimann D; Hansen C; Carlson MA. Disruption of NF-kB signaling in the Fibroblast-Populated Collagen Matrix. J Surg Res. 2014, Vol. 186: 688 Yanala UR; Noriega S; Spretz R; Ragusa J; Nunez L; Larsen G; Carlson MA. Synthetic

resorbable vs. cellulose bandage for minor hemorrhage in a porcine model. J Surg Res. 2015 H. PUBLISHED AUDIOVISUAL OR COMPUTER-BASED EDUCATIONAL MATERIALS AND COMPUTER SOFTWARE 1. 2.

3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13.

Frantzides CT; Madan AK; Carlson MA; Hasson HM. Basic Coordination Skills. Ethicon Endo-Surgery Institute; 2001. CD-ROM Carlson MA. Daily Diet Score [www.dailydietscore.com] Mark A. Carlson, M.D; 2006. Internet This is a rationally-designed nonoperative weight-reduction method, which I have made freely available on the internet. The method is essentially a _meta-diet,_ composed of a combination of weight-reduction techniques; each technique employed has previous documentation of efficacy Frantzides CT; Carlson MA. Hiatal Hernia (online monograph). Epocrates Online; 2008. Internet Frantzides CT; Carlson MA. Obesity in Adults (online monograph). Epocrates Online; 2008. Internet Frantzides CT; Carlson MA. Laparoscopic Nissen Fundoplication. Saunders Elsevier; 2009. DVD Frantzides CT; Carlson MA; Granderath FA. Laparoscopic Hiatal Herniorrhaphy. Saunders Elsevier; 2009. DVD Frantzides CT; Carlson MA; Madan AK. Minimally Invasive Left Hemicolectomy. Saunders Elsevier; 2009. DVD Carlson MA. Laparoscopic Cholecystectomy. Saunders Elsevier; 2009. DVD Frantzides CT; Carlson MA. Laparoscopic Transabdominal Inguinal Herniorrhaphy. Saunders Elsevier; 2009. DVD Frantzides CT; Carlson MA. Minimally Invasive Incisional and Ventral Herniorrhaphy. Saunders Elsevier; 2009. DVD Frantzides CT; Carlson MA. Minimally Invasive Transverse Colectomy. Saunders Elsevier; 2009. DVD Madan AK; Carlson MA; Frantzides CT. Laparoscopic Repair of Diaphragmatic Hernia. Saunders Elsevier; 2009. DVD Carlson MA. Nebraska Surgical Research [www.nebraskasurgicalresearch.com] Mark A. Carlson, M.D; 2010. Internet This web site provides information on my clinical and basic research interests and my clinical practice. There also are links to pdf files of my publications, presentations, inventions, CV, and so forth

I. PUBLISHED CONTINUING EDUCATION MATERIALS Not Applicable J. EDITORIALS 1.

Carlson MA; Longaker MT; Thompson JS. Erratum on Figure 3 of Modulation of FAK, Akt, and p53 by stress release of the fibroblast-populated collagen matrix. J Surg Res. 2004; Vol. 121: p. 151. [Editorial]

2. 3. 4. 5. 6.

7. 8.

Carlson MA; Frantzides CT. Comment on: Laparoscopic repair of large paraesophageal hiatal hernia. Surg Endosc. 2004; Vol. 18: p. 1821. [Editorial] Carlson MA; Frantzides CT. Comment on: Mesh-reinforced hiatal hernia repair. Surg Endosc. 2005; Vol. 19: p. 1423. [Editorial] Carlson MA. Comment on: Five Steps To Avoid Litigation From Lap Cholecystectomy. General Surgery News. 2009; Vol. 36. [Editorial] Carlson MA. Comment on: Single-Incision Approach Deemed Safe for Colectomy. ACS Surgery News. 2011; Vol. 7: p. 12. [Editorial] Carlson MA. Comment on: Prospective randomized clinical trial comparing laparoscopic cholecystectomy and hybrid natural orifice transluminal endoscopic surgery. Surg Endosc. 2013; Vol. 27: p. 3929-3930. [Editorial] Carlson MA. Research Priorities in Bariatric Surgery: Misplaced Emphasis on Innovation?. Ann Surg. 2013; [Editorial] Carlson MA. Response to: From Bariatric to Metabolic Surgery: New Concepts on the Rise. Ann Surg. 2014; [Editorial]

K. CONFERENCE PROCEEDING Not Applicable EDUCATION / TEACHING ACTIVITY A. GRADUATE STUDENT INSTRUCTION Stem Cell Biology UNMC Lecture: "Skin Regeneration" 1.50 hour/Y 2010 - 2012 Mentoring Alex Lesiak, University of Nebraska Medical Student Project: Effect of Hyaluronic Acid in the Fibroblast-Populated Collagen Matrix Summer 2008 Andrew Kamien, Creighton University Medical Student Project: Review of Pathologic Response to Neoadjuvant Therapy of Rectal Cancer 2011 - 2012 Daniel Gorsage, Creighton University Medical Student Project: Review of Wound V.A.C. Therapy Summer 2009 David Doyle, University of Nebraska Medical Student Project: Effect of NF-kB inhibition on the fibroblast-populated collagen matrix Summer 2012 Eric Samuelson, University of Nebraska Medical Student Project: signaling pathways stimulated by human serum in the FPCM Summer 2004 Jeremiah J. Gums, University of Nebraska Medical Student Project: FAK signaling in the fibroblast-populated collagen matrix Summer 2006, 2007 Joshua Nelson, University of Nebraska Medical Student Project: review article on classical healing vs. regeneration Academic Year 2002-2003 Mark Eichler, University of Nebraska Medical Student Project: development of linear fibroblast-populated collagen matrix model Summer 2002 Timothy Guenther, University of Nebraska Medical Student Project: RNA interference of NF-kB pathway participants in the collagen matrix Summer 2013 Timothy Koch, Creighton University Medical Student Project: determination of apoptosis in fibroblasts using the Annexin V assay Summer 2000

Teaching Responsibilities Medical School core clerkship lecture Lecture: "Acute Abdomen" Audience: third year medical students Duration: 1 hr Frequency: every other month 1999 - Present B. RESIDENT INSTRUCTION Mentoring Nitin Garg, MD, Creighton University Surgical Resident Project: Complications and Results of Ostomy Closure in a VA Hospital Setting Academic Year 2005-2006 Teaching Responsibilities Supervise/proctor Wednesday morning Resident Seminar UNMC Audience: students & residents Duration: 1 hr Frequency: two times per year 1.00 hour/S 2001 - Present C. CONTINUING EDUCATION (CE) INSTRUCTION Basic and Advanced Laparoscopic Surgery Multiple workshops in the Animate Laboratory Medical College of Wisconsin 1995 1996 Multiple workshops in the Animate Laboratory UNMC 2000 - 2002 D. ADDITIONAL INSTRUCTION Mentoring Neeley Remmers, UNMC Postdoctoral Associate UNMC Project: Development of a Porcine Cancer Model 2014 - Present Mentoring Crystal Krause, UNMC Postdoctorate in Pharmacology and Neuroscience Project: Dermal Tissue Engineering 2009 - Present Tiffany Pena, PhD candidate in Tissue Engineering Role: primary advisor 2010 - 2012 Mentoring Ujwal Yanala, UNMC Research Fellow UNMC Projects: Studies of Hemostasis in Porcine Model; Studies of Obesity and Short Bowel Syndrome in Rats 2012 - Present Teaching Responsibilities Conference: Surgical Morbidity & Mortality UNMC Faculty participantAudience: students, residents, faculty, support personnelDuration: 1 hrFrequency: weekly 1999 Present Conference: Surgical Morbidity & Mortality Omaha VAMC ModeratorAudience: students, residents, faculty, support personnelDuration: 1 hrFrequency: twice per month 1999 - 2011 Conference: Tumor Board Omaha VAMC Faculty participantAudience: students, residents, faculty, support personnel Duration: 1 hr Frequency: weekly 2008 - Present General Surgery Clinic teaching Omaha VAMC Audience: students & residents Duration: 3 hr Frequency: weekly 1999 - Present General Surgery Preoperative Conference Omaha VAMC Faculty participantAudience: students, residents, faculty, support personnel Duration: 1 hr Frequency: weekly 1999 Present Medical School core clerkship lecture Omaha VAMC Lecture: "Acute Abdomen"

Audience: third year medical students Duration: 1 hr Frequency: every other month 1999 - Present Operating room teaching Omaha VAMC Audience: students & residents Duration: 1-4 hr Frequency: two-four times per week 1999 - Present Surgical teaching rounds Omaha VAMC Audience: students & residentsDuration: 1 hr Frequency: two times per week 1999 - Present E. FACULTY ADVISING/MENTORING Sonya L. Caston-Pierre, PhD, UNMC Summer Faculty Development Program Project: survival-shape relationship in the linear fibroblast-populated collagen matrix UNMC Summer 2006