SAFETY DATA SHEET

Creation Date 20-Oct-2009

Revision Date 03-Apr-2014

Revision Number 5

SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1. Product identifier Product Description: Cat No. : Synonyms CAS-No EC-No. Molecular Formula

Chloroform, stabilized with amylene C/4966/15, C/4966/15X, C/4966/17, C/4966/17X, C/4966/27SS, C/4966/PB17, C/4966/21RSS, C/4966/10RSS, C/4966/25RSS, C/4966/30RSS, C/4966/27RSS Methane trichloride; Methenyl trichloride; Formyl trichloride 67-66-3 200-663-8 C H Cl3

1.2. Relevant identified uses of the substance or mixture and uses advised against Recommended Use Uses advised against

Laboratory chemicals All other uses

1.3. Details of the supplier of the safety data sheet Company

E-mail address

Fisher Scientific UK Bishop Meadow Road, Loughborough, Leicestershire LE11 5RG, United Kingdom [email protected]

1.4. Emergency telephone number Tel: 01509 231166 Chemtrec US: (800) 424-9300 Chemtrec EU: 001 (202) 483-7616

SECTION 2: HAZARDS IDENTIFICATION 2.1. Classification of the substance or mixture

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Chloroform, stabilized with amylene

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SECTION 2: HAZARDS IDENTIFICATION CLP Classification - Regulation (EC) No 1272/2008 Physical hazards Based on available data, the classification criteria are not met

Health hazards Acute oral toxicity Acute Inhalation Toxicity - Vapors Skin Corrosion/irritation Serious Eye Damage/Eye Irritation Carcinogenicity Reproductive Toxicity Specific target organ toxicity - (single exposure) Specific target organ toxicity - (repeated exposure)

Category 4 Category 3 Category 2 Category 2 Category 2 Category 2 Category 3 Category 1

Environmental hazards Based on available data, the classification criteria are not met Classification according to EU Directives 67/548/EEC or 1999/45/EC Xn - Harmful Symbol(s) R40 - Limited evidence of a carcinogenic effect R-phrase(s) R63 - Possible risk of harm to the unborn child R67 - Vapors may cause drowsiness and dizziness R20/22 - Harmful by inhalation and if swallowed R36/38 - Irritating to eyes and skin R48/20 - Harmful: danger of serious damage to health by prolonged exposure through inhalation For the full text of the R-phrases and H-Statements mentioned in this Section, see Section 16 2.2. Label elements

Signal Word

Danger

Hazard Statements H302 - Harmful if swallowed H331 - Toxic if inhaled H315 - Causes skin irritation H319 - Causes serious eye irritation H336 - May cause drowsiness or dizziness H351 - Suspected of causing cancer H361d - Suspected of damaging the unborn child H372 - Causes damage to organs through prolonged or repeated exposure Precautionary Statements

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SAFETY DATA SHEET Chloroform, stabilized with amylene

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______________________________________________________________________________________________ P260 - Do not breathe dust/fume/gas/mist/vapors/spray P304 + P340 - IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing P311 - Call a POISON CENTER or doctor/ physician P302 + P352 - IF ON SKIN: Wash with plenty of soap and water P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P280 - Wear protective gloves/ protective clothing/ eye protection/ face protection 2.3. Other hazards Cardiac and respiratory depression Overexposure may cause decreased heart rate, decreased blood pressure, heart block, and cardiac failure

SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS 3.1. Substances Component

CAS-No

EC-No.

Weight %

Chloroform

67-66-3

200-663-8

>99

1-Pentene

109-67-1

EEC No. 203-694-5

0.01

Note

CLP Classification Regulation (EC) No 1272/2008 Acute Tox. 4 (H302) Acute Tox. 3 (H331) Skin Irrit. 2 (H315) Eye Irrit. 2 (H319) Carc. 2 (H351) Repr. 2 (H361d) STOT RE 1 (H372) STOT SE 3 (H336) Flam. Liq. 1 (H224) Asp. Tox. 1 (H304) Aquatic Chronic 3 (H412)

DSD Classification 67/548/EEC Xn;R20/22-48/20 Xi; R36/38 Carc.Cat.3; R40 Repr.Cat.3; R63 R67

F+; R12 Xn; R65 R52/53

Amylene is used as a stabilizer, but there is evidence that it may not prevent phosgene generation. Chloroform stabilized with amylene should be tested for phosgene content.

For the full text of the R-phrases and H-Statements mentioned in this Section, see Section 16

SECTION 4: FIRST AID MEASURES 4.1. Description of first aid measures General Advice

Inhalation may cause anesthesia. Show this safety data sheet to the doctor in attendance. Immediate medical attention is required.

Eye Contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention.

Skin Contact

Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. If skin irritation persists, call a physician.

Ingestion

Do not induce vomiting. Drink 1 or 2 glasses of water. Call a physician or Poison Control Center immediately.

Inhalation

Move to fresh air. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with a respiratory medical device. Immediate medical attention is required.

Protection of First-aiders

Use personal protective equipment.

4.2. Most important symptoms and effects, both acute and delayed

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SAFETY DATA SHEET Chloroform, stabilized with amylene

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______________________________________________________________________________________________ Breathing difficulties. Unconsciousness. May cause cardiac arrhythmia. May cause cardiac arrest. Symptoms of overexposure are dizziness, headache, tiredness, nausea, unconsciousness, cessation of breathing. Causes central nervous system depression. 4.3. Indication of any immediate medical attention and special treatment needed Treat symptomatically. Signs of overdose include stupor and respiratory depression. Symptoms may be delayed.

Notes to Physician

SECTION 5: FIREFIGHTING MEASURES 5.1. Extinguishing media Suitable Extinguishing Media Substance is nonflammable; use agent most appropriate to extinguish surrounding fire.. Extinguishing media which must not be used for safety reasons No information available. 5.2. Special hazards arising from the substance or mixture Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Hazardous Combustion Products Carbon monoxide (CO), Carbon dioxide (CO2), Hydrogen chloride gas, phosgene. 5.3. Advice for firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1. Personal precautions, protective equipment and emergency procedures Ensure adequate ventilation. Use personal protective equipment. Wear respiratory protection. Keep people away from and upwind of spill/leak. Evacuate personnel to safe areas. 6.2. Environmental precautions Should not be released into the environment. See Section 12 for additional ecological Information. 6.3. Methods and material for containment and cleaning up Soak up with inert absorbent material. Keep in suitable, closed containers for disposal. 6.4. Reference to other sections Refer to protective measures listed in Sections 8 and 13.

SECTION 7: HANDLING AND STORAGE 7.1. Precautions for safe handling Wear personal protective equipment. Use only under a chemical fume hood. Do not breathe vapors or spray mist. Do not get in eyes, on skin, or on clothing. Do not ingest. Keep away from open flames, hot surfaces and sources of ignition. 7.2. Conditions for safe storage, including any incompatibilities Keep containers tightly closed in a dry, cool and well-ventilated place. Keep away from direct sunlight. Store under an inert atmosphere. Protect from moisture.

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SAFETY DATA SHEET Chloroform, stabilized with amylene

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______________________________________________________________________________________________ 7.3. Specific end use(s) Use in laboratories

SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1. Control parameters Exposure limits List source(s): EU - Commission Directive 2006/15/EC of 7 February 2006 establishing a second list of indicative occupational exposure limit values in implementation of Council Directive 98/24/EC and amending Directives 91/322/EEC and 2000/39/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. UK - EH40/2005 Containing the workplace exposure limits (WELs) for use with the Control of Substances Hazardous to Health Regulations (COSHH) 2002 (as amended). Updated by September 2006 official press release and October 2007 Supplement. IRE - 2010 Code of Practice for the Safety, Health and Welfare at Work (Chemical Agents) Regulations 2001. Published by the Health and Safety Authority. Component Chloroform

European Union Possibility of significant uptake through the skin

The United Kingdom TWA: 2 ppm TWA: 9.9 mg/m3 STEL: 6 ppm STEL: 29.7 mg/m3

Component Chloroform

Italy TWA: 2 ppm 8 ore. TWA: 10 mg/m3 8 ore. Pelle

Germany TWA: 4 ppm TWA: 20 mg/m3

Component Chloroform

Austria Haut MAK-TMW: 2 ppm 8 Stunden MAK-TMW: 10 mg/m3 8 Stunden

France Belgium Spain TWA / VLA-ED: 2 ppm (8 TWA / VME: 2 ppm (8 TWA: 2 ppm 8 uren horas) heures). restrictive limit TWA: 10 mg/m3 8 uren Huid TWA / VLA-ED: 10 TWA / VME: 10 mg/m3 (8 heures). restrictive limit mg/m3 (8 horas) Piel STEL / VLCT: 50 ppm. STEL / VLCT: 250 mg/m3. Peau Portugal TWA: 10 ppm 8 horas

Denmark Switzerland Haut/Peau TWA: 2 ppm 8 timer TWA: 10 mg/m3 8 timer STEL: 1 ppm 15 Minuten Hud STEL: 5 mg/m3 15 Minuten TWA: 0.5 ppm 8 Stunden TWA: 2.5 mg/m3 8 Stunden

The Netherlands STEL: 25 mg/m3 15 minuten TWA: 5 mg/m3 8 uren

Finland TWA: 2 ppm 8 tunteina TWA: 10 mg/m3 8 tunteina STEL: 4 ppm 15 minuutteina STEL: 20 mg/m3 15 minuutteina Iho

Poland TWA: 8 mg/m3 8 godzinach

Norway TWA: 2 ppm 8 timer TWA: 10 mg/m3 8 timer STEL: 4 ppm 15 minutter. STEL: 20 mg/m3 15 minutter. Hud TWA: 40 ppm 8 timer TWA: 275 mg/m3 8 timer

Cyprus Skin-potential for cutaneous absorption TWA: 2 ppm TWA: 10 mg/m3

Czech Republic TWA: 10 mg/m3 8 hodinách. Potential for cutaneous absorption Ceiling: 20 mg/m3

1-Pentene

Component Chloroform

Bulgaria TWA: 2 ppm TWA: 10.0 mg/m3 Skin notation

Croatia kože TWA-GVI: 2 ppm 8 satima. TWA-GVI: 10 mg/m3 8 satima.

Ireland TWA: 2 ppm 8 hr. TWA: 9.8 mg/m3 8 hr. Skin

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Chloroform, stabilized with amylene

______________________________________________________________________________________________ Component Chloroform

Estonia Nahk TWA: 2 ppm 8 tundides. TWA: 10 mg/m3 8 tundides.

Gibraltar Skin notation TWA: 2 ppm 8 hr TWA: 10 mg/m3 8 hr

Greece TWA: 10 ppm TWA: 50 mg/m3

Hungary STEL: 10 mg/m3 15 percekben. CK TWA: 10 mg/m3 8 órában. AK

Iceland TWA: 2 ppm 8 klukkustundum. TWA: 10 mg/m3 8 klukkustundum. Skin notation Ceiling: 4 ppm Ceiling: 20 mg/m3

Component Chloroform

Latvia skin - potential for cutaneous exposure TWA: 2 ppm TWA: 10 mg/m3

Lithuania

Luxembourg Possibility of significant uptake through the skin TWA: 2 ppm 8 Stunden TWA: 10 mg/m3 8 Stunden

Malta possibility of significant uptake through the skin TWA: 2 ppm TWA: 10 mg/m3

Romania Skin notation TWA: 2 ppm 8 ore TWA: 10 mg/m3 8 ore

Component Chloroform

Russia TWA: 5 mg/m3 Skin notation STEL: 10 mg/m3 vapor

Slovak Republic TWA: 2 ppm TWA: 10 mg/m3

Slovenia TWA: 2 ppm 8 urah TWA: 10 mg/m3 8 urah Koža

Sweden Turkey STV: 5 ppm 15 minuter Deri STV: 25 mg/m3 15 TWA: 2 ppm 8 saat minuter TWA: 10 mg/m3 8 saat LLV: 2 ppm 8 timmar. LLV: 10 mg/m3 8 timmar.

Biological limit values This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific regulatory bodies. Monitoring methods BS EN 14042:2003 Title Identifier: Workplace atmospheres. Guide for the application and use of procedures for the assessment of exposure to chemical and biological agents. MDHS70 General methods for sampling airborne gases and vapours MDHS 88 Volatile organic compounds in air. Laboratory method using diffusive samplers, solvent desorption and gas chromatography MDHS 96 Volatile organic compounds in air - Laboratory method using pumped solid sorbent tubes, solvent desorption and gas chromatography Derived No Effect Level (DNEL) Route of exposure

See table for values Acute effects (local)

Oral Dermal Inhalation Predicted No Effect Concentration (PNEC) Fresh water Fresh water sediment Marine water Marine water sediment Water Intermittent Microorganisms in sewage treatment Soil (Agriculture)

Acute effects (systemic)

Chronic effects (local)

333 mg/m3

2.5 mg/m3

Chronic effects (systemic) 0.94 mg/kg bw/day 2.5 mg/m3

See values below. 0.146 mg/l 0.45 mg/kg 0.015 mg/l 0.09 mg/kg 0.133 mg/l 0.048 mg/l 0.56 mg/kg

8.2. Exposure controls

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SAFETY DATA SHEET Chloroform, stabilized with amylene

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______________________________________________________________________________________________ Engineering Measures Use only under a chemical fume hood. Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source. Personal protective equipment Eye Protection

Goggles (European standard - EN 166) Protective gloves

Hand Protection Glove material Viton (R)

Breakthrough time > 480 minutes

Glove thickness -

Neoprene Butyl rubber

< 25 minutes < 15 minutes

0.45 mm 0.35 mm

Skin and body protection

EU standard Level 6 EN 374

Glove comments As tested under EN374-3 Determination of Resistance to Permeation by Chemicals

Long sleeved clothing

Inspect gloves before use. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. (Refer to manufacturer/supplier for information) Ensure gloves are suitable for the task: Chemical compatability, Dexterity, Operational conditions, User susceptibility, e.g. sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion. Remove gloves with care avoiding skin contamination. Respiratory Protection

When workers are facing concentrations above the exposure limit they must use appropriate certified respirators To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly.

Large scale/emergency use

Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.. Recommended Filter type: low boiling organic solvent, Type AX, Brown, conforming to EN371.

Small scale/Laboratory use

Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Recommended half mask:- Valve filtering: EN405 or Half mask: EN140 plus filter, EN 141 When RPE is used a face piece Fit Test should be conducted.

Hygiene Measures

Handle in accordance with good industrial hygiene and safety practice.

Environmental exposure controls

Prevent product from entering drains.

SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES 9.1. Information on basic physical and chemical properties Appearance Physical State Odor Odor Threshold pH

Colorless Liquid. aromatic sweet No data available No information available.

Melting Point/Range Softening Point Boiling Point/Range Flash Point

-63°C / -81.4°F No data available 61 - 61°C / 141.8 - 141.8°F No information available.

Method - No information available

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SAFETY DATA SHEET Chloroform, stabilized with amylene

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______________________________________________________________________________________________ Evaporation Rate Flammability (solid,gas) Explosion Limits

No data available Not applicable No data available.

Vapor Pressure Vapor Density Specific Gravity / Density Bulk Density Water Solubility Solubility in other solvents

213 mbar @ 20 °C No data available 1.480 Not applicable 8 g/L (20°C) No information available

Partition Coefficient (noctanol/water)

Component Chloroform 1-Pentene

Autoignition Temperature Decomposition temperature Viscosity Explosive Properties Oxidizing Properties

No data available No data available 0.56 mPa s at 20 °C No information available No information available

Liquid

(Air = 1.0) Liquid

log Pow 2 2.66

9.2. Other information Molecular Formula Molecular Weight

C H Cl3 119.38

SECTION 10: STABILITY AND REACTIVITY 10.1. Reactivity

Sensitivity to light Moisture sensitive.

10.2. Chemical stability Stable under normal conditions. Unstable upon depletion of inhibitor. 10.3. Possibility of hazardous reactions Hazardous Polymerization Hazardous Reactions

Hazardous polymerization does not occur. No information available.

10.4. Conditions to avoid Incompatible products, Heat, flames and sparks, Excess heat, Exposure to light, Protect from moisture. 10.5. Incompatible materials Strong oxidizing agents. Alkali metals. Aluminium. Acetone. 10.6. Hazardous decomposition products Carbon monoxide (CO), Carbon dioxide (CO2), Hydrogen chloride gas, phosgene.

SECTION 11: TOXICOLOGICAL INFORMATION 11.1. Information on toxicological effects Product Information (a) acute toxicity; Oral Dermal

No data available No data available

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SAFETY DATA SHEET Chloroform, stabilized with amylene

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______________________________________________________________________________________________ No data available

Inhalation Component Chloroform 1-Pentene

LD50 Oral 695 mg/kg ( Rat ) >2000 mg/kg (Rat)

(b) skin corrosion/irritation;

Category 2

(c) serious eye damage/irritation;

Category 2

LD50 Dermal 20 g/kg ( Rabbit ) >2000 mg/kg (Rabbit)

LC50 Inhalation 47,702 mg/L ( Rat ) 4 h 175000 mg/m3 ( Rat ) 4 h

(d) respiratory or skin sensitization; Respiratory Skin

No data available No data available

(e) germ cell mutagenicity;

No data available

(f) carcinogenicity;

Category 2 The table below indicates whether each agency has listed any ingredient as a carcinogen

Component Chloroform

EU

UK

Germany Cat. 2

(g) reproductive toxicity; Reproductive Effects Developmental Effects Teratogenicity

Category 2 Experiments have shown reproductive toxicity effects on laboratory animals. Developmental effects have occurred in experimental animals. Study result . negative.

(h) STOT-single exposure;

Category 3

(i) STOT-repeated exposure;

Category 1

Study result Target Organs

IARC Group 2B

LOAEL = 15 mg/kg bw/day NOAEC = 25 mg/m3 Liver, Kidney, Central nervous system (CNS).

(j) aspiration hazard;

No data available

Other Adverse Effects

Tumorigenic effects have been reported in experimental animals. See actual entry in RTECS for complete information Symptoms of overexposure are dizziness, headache, tiredness, nausea, unconsciousness, cessation of breathing. Causes central nervous system depression.

Symptoms / effects, both acute and delayed

SECTION 12: ECOLOGICAL INFORMATION 12.1. Toxicity Ecotoxicity effects Component

Do not empty into drains. The product contains following substances which are hazardous for the environment. Freshwater Fish

Water Flea

Freshwater Algae

Microtox

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SAFETY DATA SHEET Chloroform, stabilized with amylene

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SECTION 12: ECOLOGICAL INFORMATION Chloroform

300 mg/L LC50 96 h 71 mg/L LC50 96 h 18 mg/L LC50 96 h

EC50 = 28.9 mg/L/48h

EC50 = 560 mg/L/48h

Photobacterium phosphoreum: EC50 = 520 mg/L/5 min Photobacterium phosphoreum: EC50 = 670 mg/L/15 min Photobacterium phosphoreum: EC50 = 670 mg/L/30min

12.2. Persistence and degradability Persistence Degradation in sewage treatment plant

Product is biodegradable Persistence is unlikely, based on information available. Contains substances known to be hazardous to the environment or not degradable in waste water treatment plants.

12.3. Bioaccumulative potential

Bioaccumulation is unlikely

Component Chloroform 1-Pentene

log Pow 2 2.66

Bioconcentration factor (BCF) 13 No data available

12.4. Mobility in soil

The product contains volatile organic compounds (VOC) which will evaporate easily from all surfacesWill likely be mobile in the environment due to its volatility. Disperses rapidly in air.

12.5. Results of PBT and vPvB assessment

No data available for assessment

12.6. Other adverse effects Endocrine Disruptor Information Persistent Organic Pollutant Ozone Depletion Potential

This product does not contain any known or suspected endocrine disruptors This product does not contain any known or suspected substance This product does not contain any known or suspected substance

SECTION 13: DISPOSAL CONSIDERATIONS 13.1. Waste treatment methods Waste from Residues / Unused Products

Waste is classified as hazardous. Dispose of in accordance with the European Directives on waste and hazardous waste. Dispose of in accordance with local regulations.

Contaminated Packaging

Dispose of this container to hazardous or special waste collection point..

European Waste Catalogue (EWC)

According to the European Waste Catalogue, Waste Codes are not product specific, but application specific. Do not dispose of waste into sewer. Waste codes should be assigned by the user based on the application for which the product was used. Do not empty into drains.

Other Information

SECTION 14: TRANSPORT INFORMATION IMDG/IMO 14.1. UN number 14.2. UN proper shipping name 14.3. Transport hazard class(es) 14.4. Packing group

UN1888 Chloroform 6.1 III

ADR 14.1. UN number 14.2. UN proper shipping name 14.3. Transport hazard class(es)

UN1888 Chloroform 6.1

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SAFETY DATA SHEET Chloroform, stabilized with amylene

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______________________________________________________________________________________________ 14.4. Packing group

III

IATA 14.1. UN number 14.2. UN proper shipping name 14.3. Transport hazard class(es) 14.4. Packing group

UN1888 Chloroform 6.1 III

14.5. Environmental hazards

No hazards identified

14.6. Special precautions for user

No special precautions required

14.7. Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code

Not applicable, packaged goods

SECTION 15: REGULATORY INFORMATION 15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture X = listed

International Inventories Component Chloroform 1-Pentene

EINECS ELINCS 200-663-8 203-694-5 -

NLP

TSCA X X

DSL X X

NDSL -

PICCS X X

ENCS X X

IECSC X X

AICS X X

KECL X X

Amylene is used as a stabilizer, but there is evidence that it may not prevent phosgene generation. Chloroform stabilized with amylene should be tested for phosgene content.

Note

Component

Chloroform

REACH (1907/2006) - Annex XIV REACH (1907/2006) - Annex XVII - REACH Regulation (EC 1907/2006) Substances Subject to Authorization Restrictions on Certain Dangerous article 59 - Candidate List of Substances Substances of Very High Concern (SVHC) Use restricted. See item 32. (see http://eurlex.europa.eu/LexUriServ/LexUriServ.d o?uri=CELEX:32006R1907:EN:NOT for restriction details)

National Regulations Component Chloroform 1-Pentene

Germany - Water Classification (VwVwS) WGK 2 WGK 2

Component Chloroform

Germany - TA-Luft Class Class I : 20 mg/m3 (Massenkonzentration)

France - INRS (Tables of occupational diseases) Tableaux des maladies professionnelles (TMP) - RG 12

Take note of Control of Substances Hazardous to Health Regulations (COSHH) 2002 and 2005 Amendment Take note of Dir 94/33/EC on the protection of young people at work Take note of Dir 92/85/EC on the protection of pregnant and breastfeeding women at work Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work 15.2. Chemical safety assessment A Chemical Safety Assessment/Report (CSA/CSR) has not been conducted

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SAFETY DATA SHEET Chloroform, stabilized with amylene

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SECTION 16: OTHER INFORMATION Full text of R-phrases referred to under sections 2 and 3 R40 - Limited evidence of a carcinogenic effect R67 - Vapors may cause drowsiness and dizziness R63 - Possible risk of harm to the unborn child R20/22 - Harmful by inhalation and if swallowed R36/38 - Irritating to eyes and skin R48/20 - Harmful: danger of serious damage to health by prolonged exposure through inhalation Full text of H-Statements referred to under sections 2 and 3 H302 - Harmful if swallowed H332 - Harmful if inhaled H315 - Causes skin irritation H319 - Causes serious eye irritation H351 - Suspected of causing cancer H361d - Suspected of damaging the unborn child H336 - May cause drowsiness or dizziness H372 - Causes damage to organs through prolonged or repeated exposure Legend CAS - Chemical Abstracts Service EINECS/ELINCS - European Inventory of Existing Commercial Chemical Substances/EU List of Notified Chemical Substances PICCS - Philippines Inventory of Chemicals and Chemical Substances IECSC - Chinese Inventory of Existing Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances

TSCA - United States Toxic Substances Control Act Section 8(b) Inventory DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List ENCS - Japanese Existing and New Chemical Substances AICS - Australian Inventory of Chemical Substances NZIoC - New Zealand Inventory of Chemicals

WEL - Workplace Exposure Limit ACGIH - American Conference of Governmental Hygienists DNEL - Derived No Effect Level RPE - Respiratory Protective Equipment LC50 - Lethal Concentration 50% NOEC - No Observed Effect Concentration PBT - Persistent, Bioaccumulative, Toxic

TWA - Time Weighted Average IARC - International Agency for Research on Cancer PNEC - Predicted No Effect Concentration LD50 - Lethal Dose 50% EC50 - Effective Concentration 50% POW - Partition coefficient Octanol:Water vPvB - very Persistent, very Bioaccumulative

ADR - European Agreement Concerning the International Carriage of Dangerous Goods by Road IMO/IMDG - International Maritime Organization/International Maritime Dangerous Goods Code OECD - Organisation for Economic Co-operation and Development BCF - Bioconcentration factor

ICAO/IATA - International Civil Aviation Organization/International Air Transport Association MARPOL - International Convention for the Prevention of Pollution from Ships ATE - Acute Toxicity Estimate VOC - Volatile Organic Compounds

Key literature references and sources for data Suppliers safety data sheet, Chemadvisor - LOLI, Merck index, RTECS Training Advice Chemical hazard awareness training, incorporating labelling, Safety Data Sheets (SDS), Personal Protective Equipment (PPE) and hygiene. Use of personal protective equipment, covering appropriate selection, compatibility, breakthrough thresholds, care, maintenance, fit and standards. First aid for chemical exposure, including the use of eye wash and safety showers. Chemical incident response training. Fire prevention and fighting, identifying hazards and risks, static electricity, explosive atmospheres posed by vapours and dusts. Creation Date Revision Date Revision Summary

20-Oct-2009 03-Apr-2014 (M)SDS sections updated, 2, 3, 4, 6, 7, 11.

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SAFETY DATA SHEET Chloroform, stabilized with amylene

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This safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006 Disclaimer The information provided on this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other material or in any process, unless specified in the text.

End of Safety Data Sheet

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