High patronage of the President of the Republic

5th International Summit on Advanced Cardiac Care Dear Colleague,

Under the auspicies of

It’s our pleasure to invite you to the 5th International Summit on Advanced Cardiac Care which will take place in Verona from 8 to 9 October 2009. A better understanding of the pathophysiology of acute manifestation of coronary heart disease the development and the availability of newer pharmacologic agents and the impressive improvements of the interventional techniques aimed to limit the ischemic damage in the short term and to maintain the favorable effects on long term, have largely contributed to the improved outcome of the patients. The Summit has the purpose to promote the sharing of new information on topics related to acute coronary syndromes and ischemic heart failure, and to stimulate exchange of ideas and of experiences, through the participation of world experts in the field.

Presidency of Council of Ministers Verona General Hospital University of Verona Medical Association of Verona Veneto Region Province of Verona Town Council of Verona FIC- Italian Federation of Cardiology GISE- Italian Society of Invasive Cardiology

I hope to meet you in Verona.

A.R.C.A. Corrado Vassanelli on behalf of Summit Directors

5th International Summit on Advanced Cardiac Care Verona - Italy, 8-9 Ottobre 2009 SUMMIT DIRECTORS Maarten L.Simoons - Rotterdam, The Netherlands Corrado Vassanelli - Verona, Italy William Wijns - Aalst, Belgium Gianfranco Sinagra - Trieste, Italy SCIENTIFIC SECRETARIAT Corrado Vassanelli - Flavio L. Ribichini - Giuliana Menegatti Div. of Cardiology - University of Verona P.le A. Stefani, 1 - 37126 Verona, Italy Phone +39 045 8122320 ORGANIZING SECRETARIAT Soluzioni Omnia Media Srl Via Anfiteatro, 10 - 37121 Verona Phone +39 045 8034553 - Fax +39 045 2109966 [email protected] www.soluzioniverona.it

DIRECTORS Maarten Simoons Gianfranco Sinagra Corrado Vassanelli William Wijns

NL IT IT BE

INVITED FACULTY Joseph Alpert David Antonucci Philipp Bonhoefer Edoardo Camenzind Paolo Camici Alessandro Cappucci Fausto Castriota Angel Cequier Fillat Maria Antonietta Cicoira Filippo Crea Antonio Curnis Livio Dei Cas Ewa Jankowska Moishe Flugelman Fiorenzo Gaita Eulogio Garcia Pantaleo Giannuzzi Sabino Iliceto Ciro Indolfi Petr Kala Akihl Kapur Antoine Lafont Jean François Leclerq Giovanni Battista Luciani

USA I UK CH UK I I E I I I I PL IL I ES I I I CS UK F F I

Domenico Marchese Paolo Marino Alessandro Mazzucco M. Antonia Prioli Bernhard Reimers Flavio Ribichini Ornella Rimoldi Joachim Schoefer Michele Senni Jacob Shani Gianfranco Sinagra Thierry Folliguet Arnoud WJ Van t’Hoff Corrado Vassanelli Renu Virmani Gabriele Zanotto

I I I I I I UK D I USA I F NL I USA I

8 october 2009 8.30 - 10.30 Symposium: “Subclinical” coronary artery disease Chairmen: P.N. Marino, D. Marchese Classification of coronary microvascular dysfunction F. Crea, Roma, I Treatment of microvascular dysfunction: old and new hopes P.G. Camici, London, UK New non-invasive trials for the identification of plaque inflammation O. Rimoldi London, UK Why the diabetic atherosclerosis is different? R. Virmani, USA 10.30 - 11.45 Debate: US and EU guidelines on Acute Coronary Syndromes: an ocean between? Chairman: C. Vassanelli For USA: J. Alpert, Tucson, USA For Europa: F. Ribichini, I

11.45 - 12,15 Lecture: The percutaneous treatment of the mitral regurgitation J. Schoefer, Hamburg, Germany Presented by B. Reimers, I 12.15 - 12.45 Lecture: Last generation DES. Achieved improvements and remaining shortcomings. E. Camenzind, CH Presented by F. Ribichini, I 13.45 - 15,45 Simposium: Reperfusion strategies in Acute Coronary Syndromes Chairmen: A. Cequier Filat, J. Shani Bivalirudin is the new standard of care A. Cequier Fillat, Barcelona, ES IIb-IIIa GP inhibitors still hold the strongest evidence J. Shani, New York, USA A consolidated interventional network experience. Results of a routine and future perspectives in the Netherlands A. vant’ Hoff, Zwolle, NL

Scientific Program Pre-hospital lysis and emergency PCI in the Czech republic P. Kala, Prague, CZ Appropriate reperfusion strategy according to guidelines : state of the art A. Kapur, London UK 15.45 - 17.00 Symposium: Cell based therapies Chairmen: GF. Sinagra, M. Flugelman “In vivo” reduction of arterial aneurism by cell transfer in the rabbit carotid artery model A. Lafont, Paris, F Cell and gene therapy for angiogenesis: can it be an alternative to cell therapy for myogenesis? M. Flugelman, Haifa, IL The pathologist opinion: a nice dream or a possible future? R. Virmani, USA

17.30 - 18.45 Symposium: Get to the core: advances in risk stratification and treatment for heart failure Chairmen: M. Senni, L. Dei Cas Prognostic stratification in chronic heart failure: need for better refiniment M. Senni, Bergamo, I Steroid Hormones in heart failure: pathophysiology, prognosis and treatment E. Jankowska, Wroclav, PL Emerging strategy in acute heart failure: ultrafiltration M.A. Cicoira, Verona, I

9 october 2009 9.00 - 11.00 Symposium: Surgery vs interventional cardiology: still something to debate Chairmen: A. Mazzucco, S. Iliceto DES versus CABG. Wrap-up message after Syntax, Cardia and Freedom Cardiologist: B. Reimers, I Surgeon: T. Folliguet, F Lecture: Progress in surgical management of congenital aortic value disease, from infancy to adulthood G.B. Luciani, Verona, I 11.00 - 11.30 Lecture: Percutaneous pulmonary valve replacement P. Bonhoefer, London, UK Presented by M.A. Prioli, I 11.30 - 12.00 Lecture: Percutaneous aortic valve replacement E. Garcia, Madrid, ES Presented by D. Antonucci, I

12.00 - 13.30 Symposium: Atrial fibrillation Chairmen: Curnis, G. Zanotto Old and new therapy in atrial fibrillation A. Capucci, Ancona, I Ablation in atrial fibrillation F. Gaita, Torino, I Collateral effects of ablation in atrial fibrillation J.F. Leclerque, Paris, F 14.30 - 15.00 Lecture: Cardiovascular secondary prevention: not a luxury! The Italian way P. Giannuzzi, Veruno, I Presented by M.A. Cicoira 15.00 - 15.30 Lecture: Acute percutaneous interventions in Stroke F. Castriota, Cotignola, I Presented by B. Reimers

Scientific Program 15.30 - 16.30 Symposium: These are challenging times! Chairmen: C. Indolfi, M. Flugelman Independent clinical research enhances quality of daily health care: the case of primary PTCA F. Ribichini Verona, I Which perspectives for the future of research in cardiovascular medicine. J. Alpert, USA 16.30 - 17.15 Conclusions C. Vassanelli, Verona, I 17.15 - 17.30 ECM C. Vassanelli, Verona, I

General Information CME CREDITS The request for accreditation of the 5th International Summit on Acute Cardiac Care will be submitted for CME credits. AUDIOVISUAL EQUIPMENT Congress halls will be equipped with computer projection (Power Point presentation). Presentation should be delivered to the audiovisual center 3 hours before the start of the Session. Use of personal computer is not allowed. BADGES The official badge must be worn for admission to all scientific sessions and other activities of the Summit. CERTIFICATE OF ATTENDANCE A Certificate of Attendance will be issued by the Conference Secretariat, at the end of the Congress works, to all registered delegates upon request. CHANGES OF PROGRAM The scientific committee and the organizing secretariat reserve the right to make any change to the Congress program which might be necessary for scientific and/or technical reasons. CONGRESS VENUE Palazzo della Gran Guardia - Verona SECRETARIAT The service of the conference secretariat will be available to participants from 8.00 a.m. of October 8th and for the entire length of the summit works, with the same time schedule.

TECHNICAL AND PHARMACEUTICAL EXHIBITION will be located at the Summit Venue The exhibit hours will follow the timetable of the Congress works. INTERNET POINT Is available at Boston Scientific stand.

How to reach the congress From Airport Verona’s airport (Villafranca) is situated approximately 10 km S-W from the city centre. There is a shuttle-bus service to and from the airport every 20 minutes. From P.ta Nuova railway station The main railway station is “Verona Porta Nuova” at the crossing of railways Milan-Venice and Rome-Brenner. For information about time tables and fares: www.trenitalia.it From Verona Sud/Verona Nord Verona is reached by the A22 (Motorway Brennero/Modena exit Verona Nord) or by the A4 Motorway Serenissima (Milan/Venice - exit Verona Sud).