XL-S MEDICAL FAQ FOR HEALTHCARE PROFESSIONALS 1. HOW DOES XL-S MEDICAL WORK? XL-S Medical helps you lose up to 3x more weight than with dieting alone1. It is primarily made from Litramine™, a patented natural fibre complex containing prickly pear.

IT HAS A TRIPLE ACTION EFFECT • Reduces calories absorbed by binding dietary fat The fibre complex Litramine™ binds readily with fat from food and becomes a large fat-fibre complex in the stomach. The fat-fibre complex is too large to be absorbed in the small intestine. It is eventually excreted from the body naturally. • Can reduce appetite and food cravings The fibres in Litramine™ also expand and become a highly viscous gel that delays gastric emptying, which can help to reduce appetite and food cravings. • Can improve gastrointestinal transit The fibres contained in XL-S Medical can play an important role to improve gastrointestinal transit. 2. HOW TO TAKE XL-S MEDICAL? XL-S Medical comes in a convenient, small, discrete single-dose oral powder sachet. It means you can take it anywhere and without the need for water. Simply pour the sweet berry flavoured powder directly into your mouth after each main meal. • Take 1 sachet, 3 times a day, immediately after every main meal. Do not take more than 3 sachets per day.

• The sachets are ready-to-use. Empty the contents directly into your mouth or on your tongue and consume. • Do not pour the contents of the sachet into a drink before consuming. If preferred, you can drink water directly after placing the contents of the sachet on your tongue. • For best results XL-S Medical should be taken for at least 1 month or until you reach your desired weight. • It is important to combine XL-S Medical with a healthy eating plan and regular physical activity. As part of a healthy diet and eating plan it is recommended to drink at least 2L (8 glasses) of water It is easy to do this if you have a large glass with each meal and a small glass between meals. Drinking water may also increase your feeling of fullness at mealtime. 3. HOW LONG AFTER A MEAL CAN I TAKE XL-S MEDICAL? It is recommended to take the sachet immediately after a main meal. XL-S Medical powder binds immediately to fats in the food you have eaten. It starts working in the upper part of the stomach. If you take XL-S Medical a considerable time after you have eaten it may not work as effectively as your stomach may have already emptied. The time for this to happen is different between people.

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4. WHY SHOULD I TAKE XL-S MEDICAL, EVEN IF I SKIP A MEAL? XL-S Medical works by absorbing dietary fats and reduces appetite and food cravings. The fibres in XL-S Medical also expand and become a highly viscous gel making you feel fuller for longer. Taking XL-S Medical even if you skip a meal may help you prevent snacking in between meals. It works best if you take it 3 times a day, one sachet after each main meal.

5. DO I HAVE TO EAT 3 TIMES A DAY? Some people like to eat small meals regularly and others prefer to eat 2-3 main meals. Please eat your meals when and how it suits you and your lifestyle. It is not important how often you eat but rather the total number of calories you consume daily. For best results XL-S Medical should be taken 3 times a day in the morning, in the middle of the day and in the evening after food. If you are taking medication ensure that you take XL-S Medical 2 hours before or after your medication. Adjust when you take XL-S Medical to fit around your medication requirements. 6. CAN I TAKE MORE XL-S MEDICAL FOR BETTER RESULTS? No. Do not take XL-S Medical more than 3 times a day. Space the doses out across the day. XL-S Medical has been clinically tested and shown to be effective and well tolerated at this dose. 7. CAN I TAKE XL-S MEDICAL ONLY ONCE OR TWICE DAY INSTEAD? XL-S Medical results, showing up to 3 times more weight loss than dieting alone, are based on taking this product 3 times a day spaced across the day to coincide with meals. If you take less than the recommended dose you may not experience the same results as those found in the clinical trial. 8. I FIND IT HARD TO SWALLOW TABLETS. HOW WILL I TAKE XL-S MEDICAL? XL-S Medical comes in a convenient, small and discrete single dose oral powder sachet. It means you can take it anywhere and without the need for water. Simply pour the sweet berry flavoured powder directly into your mouth after each main meal. If preferred, you can drink a glass of water after placing XL-S Medical on your tongue. Alternatively, you can prepare your mouth with additional saliva before placing it on your tongue. Do not mix XL-S Medical in a glass of water first. 9. HOW MUCH WEIGHT WILL I LOSE WITH XL-S MEDICAL? Everyone loses weight at different rates. It is important to set yourself realistic weight loss goals. Consistent regular weight loss helps you maintain your ideal weight long term. The National Heart Foundation has set out realistic weight loss goals as per table below:

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Taking XL-S Medical is an additional step in your weight loss journey. It is best used as one part of an overall weight management plan. Effective weight management requires long-term commitment, a healthy well-balanced diet and regular physical activity. As an initial step, understand roughly how many calories you are consuming in an average day and compare it to the normal recommended average calorie consumption. • Women – 2000 calories per day • Men – 2500 calories per day Too lose weight you need to burn more calories than you consume. XL-S Medical has shown through its clinical trial that taking XL-S Medical and consuming roughly 500 calories a day fewer than the recommended daily intake you can lose up to 3 times more weight than by just dieting alone. Incorporate some regular physical activity and you will burn through additional calories. By adopting a healthy lifestyle, eating healthy foods and keeping active you are giving yourself the best chance of success. Download the XL-S Medical APP and see the appropriate sections of this website for weight loss tips, healthy eating guides and physical activity options that will suit you and your lifestyle. 10. HOW FAST WILL I LOSE WEIGHT WITH XL-S MEDICAL? Losing weight and keeping it off requires commitment to a change in lifestyle. It is important to set realistic, achievable weight-loss goals. Everyone loses weight at different rates and depends on the number of calories they eat and the amount of energy they expend each day. It will also depend on how much weight you need to lose. Steady, consistent weight loss is healthier and more sustainable than rapid weight loss from fad diets. Australian healthcare professional guidelines show that over the long term, it is best to aim for 0.5-1 kg per week. You will need to burn or consume 500-1000 fewer calories per week to achieve this weight loss trend. There may be some weeks where you do not see a change in your overall weight. You may have lost size rather than weight that week. You may like to combine weighing yourself each week together with waist circumference measurements to assess your overall weight loss. XL-S Medical reduces the number of calories absorbed from the fat in your diet and can reduce your appetite and food cravings. Wise food choices can help you eat fewer calories and regular physical activity helps you burn off some of the calories you consume. Together these will assist you achieve you weight loss goals more quickly. 11. HOW LONG SHOULD I TAKE XL-S MEDICAL? This is extremely dependent on the amount of weight that you need to lose. The clinical trial showing that you can lose up to 3 times more weight than dieting alone was conducted over 12 weeks. Consumers in Europe have taken XL-S Medical long-term and clinical data has shown it is well-tolerated. Join our free support programme to help you manage and track your weight loss, evaluate your weight loss against your target and then decide if you need to stay on the product longer to achieve your weight loss goals. It is recommended to take XL-S Medical for a minimum of 1 month or until you achieve your weight loss goals.

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12. DOES XL-S MEDICAL WORK? XL-S Medical has been clinically tested and the results have been published in “The Journal of Obesity” a highly regarded medical journal. The results showed that those taking XL-S Medical lost up to 3x more weight than dieting alone. It was also found to reduce calories absorbed from dietary fats. The main clinical study was done over 12 weeks with 123 volunteers who were classified as overweight or obese. Each volunteer agreed to complete the study in the comfort of their homes and they were given a diet plan which was 500 calories less than their daily calorie needs per day and included at least 30% fat content. The volunteers were also split into two groups. One group received a daily 3g dose of Litramine™ (the active ingredient of XL-S Medical) whilst the other group received a placebo. The volunteers did not know which group they were in.

After 12 weeks the results clearly showed on average the group who had been taking XL-S Medical lost 3x more weight than the dieters in the placebo group. It is this difference between the two groups which demonstrates how XL-S Medical can help you lose up to 3x more weight than dieting alone. To view the full clinical study publication for XLS Medical Direct please click here [insert link to published clinical paper. Ensure we have approval to link to this paper] 13. WHO CAN TAKE XL-S MEDICAL? XL-S Medical is suitable for adults over 18 years of age with a BMI>18.5. The use of this product by adolescents 12-18 years old is subject to the supervision of healthcare professionals. If you have preexisting medical conditions please consult your doctor. Do not take XL-S Medical during pregnancy or whilst breastfeeding, or if your BMI (Body Mass Index) is below 18.5.

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14. WHO SHOULD CONSULT THEIR DOCTOR BEFORE TAKING XL-S MEDICAL? •

Do not take XL-S Medical during pregnancy or whilst breastfeeding, or if your BMI (Body Mass Index) is below 18.5.

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Adolescents 12-18 years old should only take XL-S Medical under medical supervision.

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XL-S Medical contains trace amounts of oxalic acids, which are found in many other green vegetables. If you have kidney disease or kidney stones, avoid taking this product on a regular basis.

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Please consult your doctor before taking XL-S Medical: o If you are diabetic. Diabetic patients may have to adjust their daily anti-diabetic treatments. o If you use cholesterol-reducing medication. o If you have a pre-existing medical condition.

15. IS XL-S MEDICAL SUITABLE FOR OVERWEIGHT OR OBESE CHILDREN? No. XL-S Medical is only recommended for adults over 18 years of age and have a BMI greater than 18.5. Adolescents 12-18 years should be supervised by a doctor if taking this product. It should not be used in children younger than 12 years. 16. CAN I TAKE MY REGULAR MEDICATIONS WITH XL-S MEDICAL? Please consult your doctor if you take any medication or have a medical condition to ensure XL-S Medical is appropriate for you. Interaction of XL-S Medical with different medications have not been studied, however it may affect the absorption of some medications into the blood stream. Contraceptive pill or fat-soluble medications: Women taking the oral contraceptive pill or any fatsoluble medicine should not take XL-S Medical two hours before or after taking this medicine. Diabetic patients: XL-S Medical may slow down dietary sugar absorption and reduce post prandial blood glucose levels. Diabetic patients may have to adjust their daily anti-diabetic treatments Cholesterol reducing medications: XL-S Medical works by reducing the absorption of fats from food eaten. When taken together with a cholesterol-lowering medication, blood glucose levels may be further reduced. Consult your doctor prior to taking XL-S Medical together with cholesterol lowering medication. 17. IS XL-S MEDICAL WELL TOLERATED? XL-S Medical clinical studies have shown that it is well tolerated when used appropriately. The incidence of adverse side effects being reported were very rare (≤0.01%), with hypersensitivity reactions being typical of food allergies, like a rash, itching, slight swelling and mild gastrointestinal upset. In such cases, seek medical advice and discontinue treatment. Unlike some other weight loss products, XL-S Medical has no added artificial colourings, salt, stimulants or preservatives. XL-S Medical is gluten free, lactose free and vegetarian friendly. 18. DOES XL-S MEDICAL CAUSE ANAL LEAKAGE LIKE SOME OTHER WEIGHT LOSS PRODUCTS? XL-S Medical encapsulates the dietary fats forming a fat-fibre complex and is excreted from the body in a solid structure. Therefore XL-S Medical will not cause anal leakage.

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19. CAN I TAKE XL-S MEDICAL WITH ALCOHOL? There is no data to suggest that alcohol cannot be consumed with XL-S Medical. However, we would encourage that your alcohol intake is in accordance with a balanced diet and within the recommended guidelines for alcohol consumption. Alcohol is a calorie rich beverage. Limiting your alcohol intake can reduce the number of calories you are consuming, helping you reach your daily calorie target. Perhaps include alcohol on your list of occasional special treats. 20. HOW OFTEN SHOULD I WEIGH MYSELF? It is important not to weigh yourself too often as you will not have an accurate account of the amount of weight you have lost. Your weight varies across the day and will vary from day to day depending on what you have eaten, how much exercise you have done and how dehydrated you may be. You will get a better idea of how much weight you have lost if you weigh yourself once per week or fortnight on the same day at roughly the same time of day (e.g. Thursday morning before breakfast). Take your shoes off and wear similar style clothing each time. Often people choose a ‘weigh in’ day outside of the weekend as this is when they generally break their healthy eating routine and you may momentarily weigh more at this time. 21. SHOULD I MEASURE MY WAIST CIRCUMFERENCE AND HOW SHOULD I DO IT?² Measuring body mass index (BMI) and waist circumference help to identify people who may benefit from weight loss programmes. Measuring your waist circumference is a simple indication of how much body fat you have and where it is stored around your body. Regardless of an adult’s height or build, a higher than normal waist measurement is: • •

greater than 94cm for men greater than 80cm for women

The waist measurements are a guide for Caucasian men, and Caucasian and Asian women. Recommended waist measurements are yet to be determined for all ethnic groups. It is believed that they may be lower for Asian men. Waist circumference measurements are also another way of measuring the success of your weight loss programme. Some weeks you may not lose weight as measured on the scales but you may lose centimetres from around your waist. These measurements can help you to stay motivated with your weight loss programme. 22. HOW TO MEASURE YOUR WAIST CIRCUMFERENCE? 1. Find the top of your hip bones and the bottom of your ribs. 2. Breathe out normally. 3. Place the tape measure midway between these points and wrap it around your waist (usually around your navel/belly button). 4. Check your measurement ensuring that you can fit one finger between the tape measure and the body. This ensures you are not pulling the tape too tight. 5. Record the measurement taken on an exhalation (breathing out).

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23. WHAT ARE THE INGREDIENTS IN EACH XL-S MEDICAL SACHET? XL-S Medical is a sweet berry flavoured powder made from Litramine™, a patented natural fibre complex sourced from prickly pear. XL-S Medical has no added stimulants, artificial colourings, salt, or preservatives. This product is gluten free, lactose free and vegetarian friendly. Ingredients: Opuntia Ficus-Indica (Litramine™, a natural fibre complex of organic plant source prickly pear), xylitol*, lemon juice powder, cranberry juice powder, citric acid anhydrous, silica-colloidal anhydrous, blackcurrant flavour, magnesium stearate, maltodextrin. Each sachet contains 11g Opuntia Ficus-Indica ext. equiv. fresh leaf (Litramine™) *Contains xylitol (3.85g per daily dose) and may have a laxative effect or cause diarrhoea.

24. WHAT IS THE NUTRITIONAL CONTENT OF EACH XL-S MEDICAL SACHET? XL-S Medical nutritional content of the sachet is as below: • Energy - 9.6 kcal per sachet • Fat - 0.05g per sachet • Protein - 0.02g per sachet • Carbohydrates - 2.28g per sachet • Sodium - 0.14mg per sachet • Dietary fibre - 0.22g per sachet • Total Sugar - 0.07g per sachet 25. DOES XL-S MEDICAL COMPLY WITH HALAL & KOSHER REQUIREMENTS? XL-S Medical does not contain any animal or animal derivatives. However, XL-S Medical has not undertaken the halal or kosher certification process. 26. CAN I TAKE XL-S MEDICAL IF I AM ALLERGIC TO STRAWBERRIES OR BERRIES? Please note that the XLS Medical Direct Sachets contain cranberry juice powders as well as naturalidentical blackcurrant flavourings. It is not recommended to use XL-S Medical If you are allergic to berries. 27. CAN I TAKE XL-S MEDICAL IF I FOLLOW A SPECIFIC DIET? XL-S Medical has no added stimulants, artificial colourings, salt, or preservatives. This product is gluten free, lactose free and vegetarian friendly. 28. CAN I TAKE XL-S MEDICAL IF I AM VEGETARIAN? XL-S Medical does not contain any animal or animal derivatives. 2

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Grube et al. 2013. A natural fiber complex reduces body weight in the overweight and obese: A double-blind, randomized, placebo-controlled study. Obesity, 21: 58-64. doi: 10.1002/oby.20244. 12 week study, n=123 (overweight and obese patients), weight loss average of 3.83Kg in the treated group, conducted by Analyze & Realize and financed by InQpharm. 2 National Heart Foundation GP Fact Sheet 2007: Management of overweight and obesity in adults. Always read the label and use only as directed. It is important to combine XL-S Medical with a healthy eating plan and regular physical activity.

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