Tube Feeding and Transitioning to Oral Feeding Barbara McElhanon, MD Assistant Professor, Division of Pediatric Gastroenterology, Hepatology, and Nutrition & Division of Autism and Related Disabilities Medical Director, Marcus Autism Center Feeding Program

Disclosures • Nothing to disclose

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Objectives • Describe risk factors associated with feeding disorders • Recall evidence-based points related to tests and procedures • Identify practical changes that could be done in the NICU setting to reduce feeding issues and dependence on tube feeds.

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Gut Dysfunction

Vomiting/spitting is very concerning and occurs with bolus feeds; Possibly unable to PO

Intestines good, but vomiting/spitting is very concerning for whatever reason; Possibly unable to PO

Please…just eat everything by mouth so you don’t get a gtube. Well, Maybe a gtube isn’t so bad. Why aren’t you seeing an SLP yet??

All the Gut works! Still possibly unable to PO

• Safe feeding requires: – coordination of sensorimotor function, swallowing, and breathing

• Eating and food plays a central role in the parentchild relationship Marcus Autism Center

Feeding difficulties in the NICU • are COMPLEX • Can become apparent at various points • Measures include – delayed acquisition of independent enteral or oral feeding milestones – lack of progressive tolerance to increasing feeding volumes

• Related to: – – – – –

immaturity, regurg/emesis/reflux ?? normal suspicious of NEC GI dysmotility/post surgical situations ALTEs Aspiration syndromes

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Feeding difficulties in the NICU • Major challenge in sick premature infants at large tertiary care hospitals • Increasing rates of survival including those with complex aerodigestive issues • Feeding/nutrition issues are on the rise and contribute to LOS and to economic burden • Variability in care contributes to 26 billion $$ a year in US for premature birth healthcare costs. Marcus Autism Center

Food Neophobia

Dovey et al

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Picky Eating

Dovey et al

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Picky Eating- Variant of normal • Picky eating – Strong food preferences – Behaviors aimed at ending meals prematurely – Fluctuating hunger: intake varies up to 30% per day

RESOLVE WITH MINIMAL INTERVENTION Marcus Autism Center

3-10% of all children have true feeding disorders and 40-70% of children with complex medical issues.

Kerzner, B., Milano, K., MacLean, W. C., Berall, G., Stuart, S., & Chatoor, I. (2015). A Practical Approach to Classifying and Managing Feeding Difficulties. Pediatrics. http://doi.org/10.1542/peds.2014-1630

DSM-V Avoidant/Restrictive Food Intake Disorder •

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An eating or feeding disturbance (eg, apparent lack of interest in eating or food; avoidance based on the sensory characteristics of food; concern about aversive consequences of eating) as manifested by persistent failure to meet appropriate nutritional and/ or energy needs associated with one (or more) of the following: – Significant weight loss (or failure to achieve expected weight gain or faltering growth in children) – Significant nutritional deficiency – Dependence on enteral feeding or oral nutritional supplements – Marked interference with psychosocial functioning [disclaimer section] The disturbance is not better explained by lack of available food or by an associated culturally sanctioned practice. The eating disturbance does not occur exclusively during the course of anorexia nervosa or bulimia nervosa, and there is no evidence of a disturbance in which one’s body weight or shape is experienced. The eating disturbance is attributable to a concurrent medical condition or better explained by another mental disorder. When the eating disturbance occurs in the context of another condition or disorder, the severity of the eating disturbance exceeds that routinely associated with the condition or disorder and warrants additional clinical attention. Marcus Autism Center

Feeding Disorders-2 flavors • Flavor #1 – Restricted types of foods • Autism

Sharp et al 2010 Marcus Autism Center

Feeding Disorders- 2 flavors • Flavor #2 – Restricted volume of foods – Infants and children with congenital or acquired respiratory, cardiac, and gastrointestinal (GI) problems

Sharp et al 2010 Marcus Autism Center

How does this happen? • Medical problems promote conditioned food aversion – eating is associated with pain, nausea, fatigue

• Once medical condition improves- aversion may not; – infants and children will have persistent disruptive mealtime behaviors trying to avoid contact with food.

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How does this happen? • Problem behaviors persist due to negative reinforcement – naturally a parent is going to remove a feeding demand and maybe end the meal early if the kids is acting so negatively. Even gagging/vomiting etc. – Consequently, child learns to do this even better and these behaviors are inadvertently shaped and strengthened overtime. • Limited exposure to food leaves out all the key sensory, developmental, physiological, social processes which usually further stresses the parent-child interaction. Ultimately, child needs major behavioral intervention or ongoing artificial support. Marcus Autism Center

Ongoing Contributing Barriers – Aspiration/Dysphagia from any cause – Developmental Delay/Missed Milestones – Lack of standardization and evidence from OT/ST, studies, surgeons, dietitians, GI doctors! – Behavioral/Social issues • Multiple caregivers • Resources • Education Marcus Autism Center

100 90 80 70 60 50 40 30 20 10 0

N= 103 kids 38% were born between 24 and 36 weeks 74% had MR or DD Age and prematurity were NOT related to categorization.

Feeding Category (alone or in combination)

Burklow et al. 1998

This makes sense • 11.5% of all US births are