Treatment of antibiotic-resistant and non gastric MALT Lymphoma Emanuele Zucca, MD Unità Linfomi IOSI, Ospedale San Giovanni, Bellinzona
MALT Lympho...
Treatment of antibiotic-resistant and non gastric MALT Lymphoma Emanuele Zucca, MD Unità Linfomi IOSI, Ospedale San Giovanni, Bellinzona
MALT Lymphoma: Evidence of antigen-driven growth • histological features of MALT lymphoma • somatic hypermutation of immunoglobulin gene (and intraclonal variation) • association with chronic infectious conditions and auto-immune processes • therapeutic efficacy of antibiotics
Helicobacter pylori
Infectious etiology of gastric MALT-lymphoma
Zucca E et al. Clin Cancer Res Oct 2014 20:5207-5216
Different chromosomal translocations affecting the same signalling pathway in MALT lymphoma
Wyld-type MALT1 synergizes with BCL10 to activate NF-B