207 S.

California Center for

CLINICAL RESEARCH

Santa Anita Street, Suite P30 San Gabriel, CA 91776 Tel: 626-284-8401 Fax: 626-284-8636 www.researchcalifornia.corn

Tom S. Chang, MD [email protected] LICENSE

California State Medical License No. A69909 British Columbia Medical License - 1995 Georgia State Medical License - 1994 FRCS(C ) - 1993 Diplomate of the ABO - 1993 FLEX certificate - 1993 Ontario Medical License - 1989-94 LMCC - 1989 DEA: BC6563286

PROFESSIONAL MEMBERSHIPS

American Academy of Ophthalmology Retina Society - 2000 Macula Society — January 2000 American Society of Retina Specialists - October 2000 Club Vit - July 1999 Umbo Society - June 1996

PROFESSIONAL AFFILIATIONS

California Center for Clinical Research 207 S. Santa Anita Dr., Ste P30 San Gabriel, CA 91776 Tel: (626) 284-8401 Fax; (626) 284-8636 Retina Institute of California 800 S. Fairmount Ave., Ste 312 Pasadena, CA 91105 Tel: (626) 568-8839 Fax: (626) 583-8838 Retina Institute of California 17138-B Colima Road Hacienda Heights, CA 91745 Tel: (626) 965-8895 Fax: (626) 965-8876 Retina Institute of California 72301 Country Club Dr., Ste 109 Rancho Mirage, CA 92270 Tel: (760) 779-0800 Fax: (760) 779-0801

Leaders in Clinical Trials

Tom S. Chang, MD CV PAGE 2

Retina Institute of California 160 E. Artesia Street, Ste 120 Pomona, CA 91767 Tel: (909) 629-5965 Tel: (909) 629-5968 EDUCATION & TRAINING

Postgraduate Master of Health Science in Epidemiology

University of British Columbia Dept. of Health Care and Epidemiology 1999 Clinical post-graduate training: Vitreo-retinal Surgery Fellowship Emory University. Atlanta, Georgia (Drs. Tom Aaberg, Paul Sternberg, Tony Capone, Dan Martin, Jennifer Lim.) 1994-95 Macular Diseases Fellowship Bascom Palmer Eye Institute. Miami, Florida (Dr. J Donald M. Gass) 1993-94 Ophthalmic Pathology Fellowship Johns Hopkins/Wilmer. Baltimore, Maryland (Dr. W Richard Green) 1992-93 Resident in Ophthalmology University of Western Ontario. London, Ontario 1989-92 General Comprehensive Medical Internship Toronto General Hospital. Toronto Ontario 1988-89 Undergraduate Medical Degree University of Toronto Medical School. Toronto, Ontario 1984-88 Major: Physical Chemistry University of Western Ontario. London, Ontario 1982-84

Tom S. Chang, MD CV PAGE 3

SSGHD Sir John A. Macdonald C.I. (Graduated second in my class). 1982

PROFESSIONAL POSITIONS

2010 to present California Center for Clinical Research Investigator 11/2005 — present Retina Institute of California Principal Investigator 1999 - 11/2005 Department of Ophthalmology University of Southern California School of Medicine Associate Professor 2000 — 11/2005 Doheny Macular Degeneration Center Pasadena, California Medical Director Undergraduate Medical Education Department of Ophthalmology USC School of Medicine Director Department of Ophthalmology USC School of Medicine Medicare Compliance Officer Retina Service Department of Ophthalmology USC School of Medicine Fellowship Program Director AAO journal — Ophthalmology Associate Editor Editorial Board Editorial Advisory Board AAO Basic Clinic and Science Course, Section 12, Retina-Vitreous Author Evidence-Based Eye Care Editorial Board

Tom S. Chang, MD CV PAGE 4 Oculex Pharmaceuticals Principal Investigator for Clinical Trials Bausch & Lomb Sub-Investigator for Clinical Trials 1998-99 University of British Columbia Assistant Professor of Ophthalmology 1995-98 University of British Columbia Clinical Instructor American Board of Ophthalmology Associate Examiner RESEARCH ACTIVITIES

1. Principal Investigator: A prospective randomized multicenter trial

investigating the utility of prophylactic scleral buckles in the prevention of retinal detachments in Macular hole patients (Awarded by the E.A. Baker Foundation: $26,000) 2. Principal Investigator: A phase I/II randomized, double masked, multi-center, dose ranging placebo-controlled trial to assess the safety, tolerability and efficacy of dexamethasone posterior segment drug delivery system (DEX PS DDS) in the treatment of inflammation following pars plana vitrectomy 3. Principal Investigator: A phase II randomized, multicenter, controlled trial to assess the safety and effectiveness of dexamethasone posterior segment drug delivery system (DEX PS DDS) in the treatment of persistent macular edema (Oculex Pharmaceuticals) 4. Principal Investigator: A pilot study to evaluate suprachoroidal triamcinolone acetonide therapy for advanced exudative age-related macular degeneration (ARMD) 5. Principal Investigator: Registry of Visudyne Age-Related Macular Degeneration (AMD) Therapy (QLT, Inc.) 6. Principal Investigator: Ranibizumab for Edema of the Macula in Diabetes: A Phase 2 Study (The READ-2 Study) 7. Co-Investigator: Pars Plana Vitrectomy and Incision of Branch Vein Venous Sheath for Branch Retinal Vein Occlusion 8. Co-Investigator: A Calcium and Magnesium Free Retinal Detachment Solution for Macular Translocation Surgery for Age-

Tom S. Chang, MD CV PAGE 5

Related Macular Degeneration 9. Co-Investigator: A Multi-Center, Prospective, randomized Study of Prophylactic Scleral buckling of Blunt-Type, Penetrating and Perforating, Posterior Segment Open-Globe Injuries. 10. Co-Investigator: Transpupillary Thermotherapy of Subfoveal Occult Choroidal Neovascularization in Patients with Age-Related Macular Degeneration 11. Principal Investigator: A Randomized, Controlled Study of the Safety, Tolerability and Biological Effect of Repeated Intravitreal Administration of VEGF Trap in Patients with Neovascular AgeRelated Macular Degeneration (Regeneron Pharmaceuticals) 12. Principal Investigator: A 24-month Randomized, Double-Masked, Controlled MultiCenter, Phase IIIB Study Assessing Safety and Efficacy of Verteporfin (Visudyne) Photodynamic Therapy Administered In Conjunction with Ranibizumab (Lucentis) Versus Ranibizumab (Lucentis) Monotherapy in Patients with Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration (Novartis) 13. Principal Investigator: A Phase III, Multicenter, Randomized, Sham Injection-Controlled Study of the Efficacy and Safety of Ranibizumab Injection Compared with Sham in Patients with Macular Edema Secondary to Branch Retinal Vein Occlusion (Genentech) 14. Principal Investigator: A Phase III, Multicenter, Randomized, Sham Injection-Controlled Study of the Efficacy and Safety of Ranibizumab Injection Compared with Sham in Subjects with Macular Edema Secondary to Central Retinal Vein Occlusion (Genentech) 15. Principal Investigator: A Phase III, Double-Masked, Multicenter, Randomized, Sham-Controlled Study of the Efficacy and Safety of Ranibizumab Injection in Subjects with Clinically Significant Macular Edema with Center Involvement Secondary to Diabetes Mellitus (Genentech) 16. Principal Investigator: A Phase I Open-Label, Dose Escalation Trial of REDD14NP Delivered by a Single Intravitreal Injection to Patients with Choroidal Neovascularization (CNV) Secondary to Exudative Age-Related Macular Degeneration ("Wet AMD") (Quark Biotech Inc) 17. Principal Investigator: A Randomized, Double Masked, Active Controlled Phase III Study of the Efficacy, Safety, and Tolerability

Tom S. Chang, MD CV PAGE 6

of Repeated Doses of Intravitreal VEGF Trap in Subjects with Neovascular Age-Related Macular Degeneration (Regeneron Pharmaceuticals) HONORS & AWARDS

Award for Excellence in Resident Training. The Doheny Eye Institute & Department of Ophthalmology at the University of Southern California Keck School of Medicine; 2003 Awarded 0-1 Visa from the Department of Inunigration and Naturalization Services. (Granted to individuals of extra-ordinary abilities) Sept 1999 E.A. Baker Foundation Fellowship Grant. The Canadian National Institute for the Blind; 1993 Alcon Book Prize for Resident Research. Alcon Laboratories; 1992 The PSI Foundation Research Award; 1991 Supervised the weekly Retinal Rounds (attended by all residents, fellows and attendings). Vancouver Hospital representative for Postgraduate Residency Training Committee Participant in the Resident's day research committee Judge: Resident's day research competition. UBC Dept. of Ophthalmology May 2, 1997 Director of Continuing Medical Education at University of British Columbia Participant in annual "Update for General Practitioners" course

LECTURES & PRESENTATIONS

Oops — There Goes the Capsule: How to Prevent and How to Treat The Annual Rosen Symposium 2007 Kingston, Ontario Canada — May 18, 2007 Drug Delivery Systems for AMD The Annual Rosen Symposium 2007 Kingston, Ontario Canada — May 18, 2007 Ranibizumab (Lucentis) Vision-Specific Quality of Life Through 24 Months in Neovascular AMD Subjects in Marina: A Phase III Clinical Trial 2006 Annual Meeting — American Society of Retina Specialists Cannes, France — September 9 — 13, 2006 The Top 10 Reasons to Receive a Retina Consult Annual Southern California College of Optometry CE Forum Torrance, CA — August 13, 2006

Tom S. Chang, MD CV PAGE 7

Self-Reported Vision Specific Quality of Life at 1 year in patients with Age-Related Macular Degeneration in two Phase III Randomized Clinical Trials of Ranibizumab (Lucentis) 2006 Association for Research in Vision and Opthalmic Annual Meeting Fort Lauderdale, FL — April 30 — May 4, 2006 Ranibizumab (Lucentis) Self-Reported Vision Specific Quality of Life through 12 months in Age-Related Macular Degeneration Patients with Minimally Classic or Occult with No Classic Chorodial Neovascularization in a Phase III Randomized Clinical Trial 29 th Annual Meeting The Macula Society San Diego, CA — February 22-25, 2006 Minimally Invasive Submacular Hermorrhage Evacuation 21 St Annual Meeting American Society of Retina Specialists New York, NY — August 16, 2003 Minimally Invasive Submacular Surgery Evacuation 6th Annual Club Vit Meeting Lake Tahoe, CA — June 25, 2003 Minimally Invasive Surgical Management of Sub-Macular Hemorrhage 34th Annual Doheny Days Conference Los Angeles, CA — June 13, 2003 General Vitrectomy Bausch & Lomb St. Louis, MO — April 2, 2003 Current 25-gauge Instrument Development and Techniques Retina Congress 2002 San Francisco, CA — September 28 — October 2, 2002 25 gauge Vitrectomy Systems AIM & ALACCSA Ophthalmology Joint Meeting Aruba — September 7, 2002 New Techniques in Pneumatic Retinopexy AIM & ALACCSA Ophthalmology Joint Meeting Aruba — September 7, 2002 Outcomes Analysis in Retinal Diseases AIM & ALACCSA Ophthalmology Joint Meeting Aruba — September 7, 2002 New Instrumentation for Macular Surgery Columbia River Gorge Vitreoretinal Update Portland, Oregon — July 19 — 20, 2002

Tom S. Chang, MD CV PAGE 8

Inverted Pneumatic Retinopexy: A Method of Treating Retinal Detachments Associated with Inferior Retinal Breaks Macula Society Barcelona, Spain — June 12 — 15, 2002 How to Get Your Manuscripts Published in Ophthalmology — the Journal of the American Academy of Ophthalmology University of Western Ontario, London, Ontario Canada — May 16, 2001 How to Get Your Manuscripts Published in Ophthalmology — the Journal of the American Academy of Ophthalmology Case presentations Queen's University, Kingston, Ontario Canada — May 18, 2001 Advances in the Diagnosis and Management of Diabetic Retinopathy, Macular Hole, and Retinopathy of Prematurity and An Inside Look at the Editorial Office of the Journal Ophthalmology Al Bahar Eye Center, The first Kuwait Vitreoretinal Meeting Kuwait, UAE — March 10 & 11, 2001 Age Related Macular Degeneration Community Lunch and Learn Doheny Eye Institute — February 21, 2001 Recent Advances in Macular Surgery The Canadian Association of Optometrists Annual Conference Vancouver, BC — February 15 — 18, 2001 Sub-Macular Surgery Fellows' Forum Chicago, IL — February 2 — 4, 2001 Pneumatic Displacement of Macular Hemorrhage Research Study Club Midwinter Conference Los Angeles, CA January 26 - 27, 2001 Poster Presentation: IRVAN Syndrome: New Observations and a Proposed Staging System The Retina Society 2000 Miami, Florida, November 30 — December 3, 2000 How to Read and Write a Scientific Paper American Academy of Ophthalmology Annual Meeting Dallas, TX — October 25, 2000 What's New in Macular Surgery? JCAHPO Dallas, TX - October 21, 2000

Tom S. Chang, MD CV PAGE 9

Surgical Management of Age-Related Macular Degeneration Loma Linda University Loma Linda, California - May 12, 2000 Contemporary Macular Surgery ORBIS International Yangon, Myanmar — February 2000 Isaac Bekhor Lecture Quality of Life Assessments in Macular Disease DEI — November 5, 1999 Up-date on the IRVAN Syndrome Vitreous Society Rome, Italy — September 17-21, 1999 Macular Translocation Surgery ORBIS International Langzhou, China — July 1999 Surgery Indications for Macular Degeneration Macula Symposium-McGill University Montreal, Canada — June 4-5, 1999 New Techniques for Macular Surgery University of British Columbia Grand Rounds Vancouver, Canada — June 11, 1999 Inverted Pneumatic Retinopexy. Canadian Ophthalmologic Society Halifax, Canada — June 24-28, 1999 Surgical Indications for Macular Degeneration Macular Degeneration Symposium McGill University, Montreal, Canada - June 4, 1999 Macular Surgery Pearls and Pitfalls ORBIS International Fes Morrocco — May 1999 Most Maculopathies Doheny Eye Institute Grand Rounds Los Angeles - February 26, 1999 Eye Diseases in Asians International Conference on Health Problems Related to Chinese in North America. Los Angeles - August 21, 1998

Tom S. Chang, MD CV PAGE 10

Surgical Removal of Dropped Intraocular Lenses ORBIS International Beijing China — August 1998 A Retrospective Review of Prophylactic Scleral Buckle Canadian Ophthalmological Society Calgary, Alberta - June 1998 General Ophthalmologist Seminar Eye Care Centre Vancouver, BC — May 23, 1998 Choroidal Detachment Dept of Ophthalmology Grand Rounds Eye Care Center Vancouver BC - December 12, 1997 Prophylactic Scleral Buckles in Vitrectomy for Macular Hole Dept. of Surgery - Epidemiology Rounds VHHSC. Vancouver BC - December 11, 1997 Most Missed Maculopathies Dept of Ophthalmology Grand Rounds Eye Care Center. Vancouver BC - September 26, 1997 Pediatric Vitreo-Retinal Surgery Pediatric Retina Symposium Eye Care Center, Vancouver BC - September 4, 1997 Diabetic Eye Care Diabetic Health Symposium Chinese Cultural Center Vancouver BC - May 4, 1997 Asian Retinopathy Study Association for Research in Vision and Ophthalmology Ft. Lauderdale Fl. - May 1997 Fundus Examination for Family Doctors Dept of Ophthalmology GP Refresher Course Vancouver BC - April 24, 1997 The Effect of Carotid Occlusive Disease on Diabetic Retinopathy Intercity Vascular Surgery Rounds Vancouver, BC - March 26, 1997. Contemporary Management of Choroidal Neovascularization British Columbia Society of Eye Physicians and Surgeons Annual General Meeting Vancouver, BC - March 14, 1997

Tom S. Chang, MD CV PAGE 11

New Methods in Vitrectomy Surgery Surgical Nurse's Rounds, BC's Children's Hospital Vancouver, BC - February 12, 1997 Does Race Play a Role in Macular Disease Bath Macula Symposium Bath, England - June 1996 Diffuse Unilateral Subacute Neuro-Retinitis Syndrome Canadian Ophthalmologic Society 1996 Ottawa, Ontario - June 1996 Idiopathic Retinal Vasculitis Aneurysms and Neuro-Retinitis Syndrome Association for Research in Vision and Ophthalmology 1995 Fort Lauderdale, Florida - May 1996 Mitochondrial Encephalomyopathy Syndrome Canadian Ophthalmologic Society Toronto, Ontario - 1995 Idiopathic Retinal Vasculitis Aneurysms and Neuro-Retinitis Syndrome Canadian Ophthalmologic Society Vancouver, BC - June 28-30, 1995 Echographic Findings in Benign Reactive Lymphoid Hyperplasia of the Choroid Bascom Palmer Research Day Miami, Florida - April 19, 1995 Histopathologic Features of Macular Hole Operculum South East Vitreo-Retinal Surgery Symposium Atlanta, Georgia - February 10, 1995 Histopathologic Evaluation of a Choroidal Neovascular Membrane Identified by ICG Angiography Canadian Ophthalmologic Society Montreal, Quebec - June 26, 1994 Diagnostic Vitrectomy Queens University - January 20-21, 1994 Contemporary Management of Macular Hole University of Toronto - November 20-21, 1993 PUBLICATIONS RECORD

1. Chang TS, Hooper PL, Gonder JR, Shum D. Trans-scleral

neodymium: YAG retinal photocoagulation in rabbit eyes. Canadian Journal of Ophthalmology. 1992; 27(7):326-30.

Tom S. Chang, MD CV PAGE 12 2. Chang T, Gonder J, Ventresca M. Low dose Tamoxifen Retinopathy. A case report of retinopathy resolution. Canadian Journal of Ophthalmology 27(3):148-9. 3. Chang T, Brewer L, Hooper P. Primary herpes simplex iridocyclitis with iris atrophy. Archives of Ophthalmology 1993;111(1):25-6. 4. Chang T, Gonder J, Hooper P. Trans-scleral YAG retinal photocoagulation. A new therapeutic modality. Canadian Journal of Ophthalmology 1992;27;326-30. 5. Chang T, Johns D, Maumence I, Walker D, Green WR. Ocular clinicopathologic study of the mitochondrial encephalomyopathy overlap syndromes. Archives of Ophthalmology 1993;111(9):125462. 6. Chang T, McFarlane D, Oliver G, Willis NR. Congenital trichomegaly, pigmentary degeneration of the retina and growth retardation (Oliver-McFarlane syndrome):28-year follow-up of the first reported case. Canadian Journal of Ophthalmology. 1993;28(4):191-3. 7. Chang T, Chapman B, Heathcote JG. Inverted Mucoepidermoid Papilloma of the conjunctiva. Canadian Journal of Ophthalmology. 1993;28: 184-6. 8. Chang T, Stark W, Green WR, Corneal decompensation associated with the Kearns-Sayre syndrome. A clinico-pathologic correlation. Cornea 1994:13(3):269-73. 9. Chang T, Freund B, De la Cruz Z, Yannuzzi L, Green WR. Clinicopathologic correlation of choroidal neovascularization demonstrated by indocynanine green angiography in a patient with retention of good vision for almost four years. Retina 1994;14(2):114-24. 10. Rafuse P, Mills D, Hooper P, Chang T, Wolf R. Effects of Valsalva's maneuver on intraocular pressure. Canadian Journal of Ophthalmology 1994;29(2):73-6. 11. Bynoe L, Chang TS, Funata M, Del Priore LV et al. Histopathologic examination of vascular patterns in subfoveal neovascular membranes. Ophthalmology 1994;101;(6):1112-1 7 . 12. Chang TS, Aylward W, Clarkson JG, Gass JDM. Asymmentric canthaxanthins retinopathy. American Journal of Ophthalmology June 1995; 119(6):801-2

Tom S. Chang, MD CV PAGE 13

13. Olsen TW, Chang TS, Sternberg P. Retinal detachments associated with blunt trauma. Seminars in Ophthalmology 1995;10(1):17-27. 14. Chang TS, Oliver G, Maberley AL, Mieler B, Davis J, Gass JDM. Idiopathic retinal vasculitis, aneurysms and neuroretinitis. Retinal Vasculitis Study. Ophthalmology 1995; 102(7):1089-97. 15. Karp CL, Scott IU, Chang TS, Plugfelder SC. Conjunctival intraepithelial neoplasia: A possible marker for human immunodeficiency virus infection?. Archives of Ophthalmology 1996;114(3):257-61. 16. Chang TS, Byrne SF, Johnson R, Gass JDM, Murray T. Echographic findings in benign reactive lymphoid hyperplasia of the choroid. Archives of Ophthalmology 1996;114(6):669-75. 17. HoYuen V, Hooper PL, Chang TS. Diffuse Unilateral Subacute Neuro-retinitis (DUSN) in Canada. Archives of Ophthalmology. Oct 1996;114 (10)1279-82. 18. Karp CL, Scott IU, Green WR,Chang TS, Culbertson WW. Central cloudy corneal dystrophy of Francois. A clinicopathologic study. Archives of Ophthalmology. Aug 1997;115(8):1058-62. 19. Proctor B, Chang TS, Hay D. Parafoveal Telangiectasia in association with CREST Syndrome. Archives of Ophthalmology. June 1998;116(6):814-15. 20. Aylward GW, Chang TS, Pautler SE, Gass JDM. A long-term follow-up of Choroidal Osteoma. Archives of Ophthalmology. Oct 1998; 116:1337-1341. 21. Chang TS, Tawansy K, Hay D, Holland S. Endophthalmitis induced by Chryseomonas Indologen. Archives of Ophthalmology. Nov 1998;116(11):1533-4. 22. Chang TS, Hay D. Courtright P. Age-related macular degeneration in Chinese-Canadians. Canadian Journal of Ophthalmology. Aug 1999;34(5):266-71. 23. Chang TS, McGill E, Hay D, Maberley AL, Ross WH, Ma PE, Potter MJ. Prophylactic scleral buckle for prevention of retinal detachment following vitrectomy for macular hole. British Journal of Ophthalmology Aug. 1999; 83(8): 944-8. 24. Chang C, Hay D, Chang TS, Nguyen RL, Christopher J. Lyons. Retinal periphlebitis in a patient with pineal germinoma. Archives of Ophthalmology 1999;117:1434-36.

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25. Linder M, Chang TS, Scott IU, Hay D, Chambers K, Sibley LM, Weis E. Validity of the visual function index (VF-14) in patients with retinal disease. Archives of Ophthalmology 1999;117(12): 1611-16. 26. Potter MJ, Chang TS, Lee AS, Rai S. Improvement in macular function after retinal translocation surgery in a patient with agerelated macular degeneration. American Journal of Ophthalmology. 2000; 129(4): 547-9. 27.Chang TS, Minckler D. Should Journal clubs play a role in the

peer-review process? Ophthalmology Editorial. June 2000. 28.Chang TS, Retinal detachments after macular hole surgery.

British Journal of Ophthalmol Letter to the Editor, June 2000, p.673. 29. Mackenzie PJ, Chang TS, Scott I, Linder, M. Assessment of Vision-Related Quality of Life in Patients with Age-related Macular Degeneration. Ophthalmology. 2002; 109(4):720-729 30. Mackenzie PJ, Chang TS, Hay D. Posterior Retinal Vasculitis Associated with Multiple Sclerosis. Retina. 2002 Feb;22(1):133-4 31. Wong CA, Potter MJ, Cui JZ, Chang TS, Ma P. Maberly AL, Ross WH, White VA, Samad A, Jia W, Homan D, Matsubara JA. Induction of Proliferative Vitreoretinopathy by a Unique Line of Human Retinal Pigment Epithelial Cells. Can J Ophthalmol. 2002 Jun;37(4)211-20 32. Fujii GY, de Juan E Jr., Sunness J, Humayun MS, Pieramici DJ, Chang TS. Patient Selection for Macular Translocation Surgery Using the Scanning Laser Ophthalmoscope. Ophthalmology. 2002 Sep; 109(9): 1737-44 33. Globe DR, Levin S, Chang TS, Mackenzie PJ, Azen S. Validity of the SF-12 Quality of Life Instrument in Patients with Retinal Diseases. Ophthalmology. 2002 Oct; 109(10): 1793-1798 34. Fujii GY, de Juan E Jr., Humayun MS, Pieramici DJ, Chang TS, Ng E, Barnes A, Wu SL, Sommerville DN. A new 25-gauge Instrument System for Transconjunctival Sutureless Vitrectomy Surgery. Ophthalmology. 2002 Oct; 109(10): 1807-12 35. Fujii GY, de Juan E Jr., Humayun MS, Chang TS, Pieramici DJ, Barnes A, Kent D. Initial Experience Using the Tranconjunctival Sutureless Vitrectomy System for Vitreoretinal Surgery. Ophthalmology. 2002 Oct; 109(10): 1814-20

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36. Fujii G, de Juan E Jr., Humayun MS, Chang TS. Limited Macular Translocation for the Management of Subfoveal Choroidal Neovascularization After Photodynamic Therapy. American Journal of Ophthalmology. 2003 Jan;135(1):109-12 37.Chang TS, Pelzek CD, Nguyen RL, Purohit SS, Scott GR, Hay D.

Inverted Pneumatic Retinopexy: A Method of Treating Retinal Detachments Associated with Inferior Retinal Breaks. Ophthalmology. 2003 Mar;110(3):589-594 38. Fujii GY, de Juan E Jr, Humayun MS, Sunnes JS, Chang TS, Rossi JV. Characteristics of visual loss by scanning laser ophthalmoscope microperimetry in eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration. American Journal of Ophthalmology. 2003 Dec; 136(6): 1067-78 39. Quillen DA, Davis JB, Gottlieb JL, Blodi BA, Callanan DG, Chang TS, Equi RA. The White Dot Syndromes. American Journal of Ophthalmology. 2004 Mar;137(3):538-50 40. Charonis A, Chang TS. Anterior segment complications associated with scleral buckling. Ophthalmol Clin North Am. 2004 Dec; 17(4):545-56 41. Lakhanpal RR, Humayun MS, de Juan E Jr, Lim JI, Chong LP, Chang TS, Javaheri M, Fujii GY, Barnes AC, Alexandrou TJ. Outcomes of 140 Consecutive Cases of 25-gauge Transconjunctival Surgery for Posterior Segment Disease. Ophthalmology. 2005 May; 112(5):817-24 42. Chaum E, Fawzi A, Chang TS, Shah GK. Diagnostic and Therapeutic Challenges. Retina. 2006 Feb; 26(2):219-22 43. Bressler N, Chang TS, Fine JT, Dolan CM, Ward J. Archives of Ophthalmology. 2009 Jan; 127(1):13-21 44.Chang TS, Kokame, Gregg MD; Casey, Raynor MD; Prenner,

Jonathan MD; Feiner, Leonard MD, PhD; Anderson, Nick MD. RETINA. 2009 October; Volume 29 — Issue 9 — pp 1235-1241 BOOK CHAPTERS Chang TS, Mackenzie P. Assessment of Visual Function and Quality of

Life (QOL) in Patients with Age-Related Macular Degeneration. In: Lim JI, ed. Age Related Macular Degeneration. New York 2002. Chapter 26, 511-522.