The qualities of whey protein • Overview • Biological value of whey protein – Nutritional value – Effect on diabetes – Exercise performance
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Immunity Satiety Allergy Acne Conclusions
Paolo Tessari et al. Slow versus fast proteins in the stimulation of beta-cell response and the activation of the enteroinsular axis in type 2 diabetes. Diabetes/Metabolism Research and Reviews 2007;23(5): 378-385.
Mortensen LS, Hartvigsen ML, Brader LJ, Astrup A, Schrezenmeir J, Holst JJ, Thomsen C, Hermansen K. Differential effects of protein quality on postprandial lipemia in response to a fat-rich meal in type 2 diabetes: comparison of whey, casein, gluten, and cod protein. Am J Clin Nutr 2009: ajcn.2008.27281.
Drucker DJ. Enhancing the Action of Incretin Hormones: A New Whey Forward? Endocrinology 2006;147(7): 3171-3172.
Akhavan T, Luhovyy BL, Brown PH, Cho CE, Anderson GH. Effect of premeal consumption of whey protein and its hydrolysate on food intake and postmeal glycemia and insulin responses in young adults. Am J Clin Nutr 2010;91(4): 966-975.
Petersen B, Ward L, Bastian E, Jenkins A, Campbell J, Vuksan V. A whey protein supplement decreases post-prandial glycemia. Nutrition Journal 2009;8(1): 47.
Whey protein improves strength during resistance training • Cribb PJ, Williams AD, Carey MF, Hayes A. The effect of whey isolate and resistance training on strength, body composition, and plasma glutamine. Int J Sport Nutr Exerc Metab 2006;16(5): 494-509. • Hayes A, Cribb PJ. Effect of whey protein isolate on strength, body composition and muscle hypertrophy during resistance training. Curr Opin Clin Nutr Metab Care 2008;11(1): 40-44.
The qualities of whey protein • Overview • Biological value of whey protein – Nutritional value – Effect on diabetes – Exercise performance
• • • • •
Immunity Satiety Allergy Acne Conclusions
Rusu D, Drouin R, Pouliot Y, Gauthier S, Poubelle PE. A bovine whey protein extract can enhance innate immunity by priming normal human blood neutrophils. J Nutr 2009;139(2): 386-393.
Rusu D, Drouin R, Pouliot Y, Gauthier S, Poubelle PE. A bovine whey protein extra can enhance innate immunity by priming normal human blood neutrophils. J Nutr 2009;139(2): 386-393.
Whey supplementatiohn in HIV patients
Sattler Am J Clin Nutr 2008 1313-21
Zavorsky GS, Kubow S, Grey V, Riverin V, Lands LC. An open-label doseresponse study of lymphocyte glutathione levels in healthy men and women receiving pressurized whey protein isolate supplements. International Journal of Food Sciences and Nutrition 2007;58(6): 429 - 436.
Poulin Y, Bissonnette R, Juneau C, Cantin K, Drouin R, Poubelle PE. XP-828L in the treatment of mild to moderate psoriasis: randomized, double-blind, placebo-controlled study. Altern Med Rev 2007;12(4): 352-359.
Numan SC, Veldkamp P, Kuijper EJ, van den Berg RJ, van Dissel JT. Clostridium difficile-associated diarrhoea: bovine antiClostridium difficile whey protein to help aid the prevention of relapses. Gut 2007;56(6): 888-889.
Young KWH, Munro IC, Taylor SL, Veldkamp P, van Dissel JT. The safety of whey protein concentrate derived from the milk of cows immunized against Clostridium difficile. Regulatory Toxicology and Pharmacology 2007;47(3): 317-326.
The qualities of whey protein • Overview • Biological value of whey protein – Nutritional value – Effect on diabetes – Exercise performance
• • • • •
Immunity Satiety Allergy Acne Conclusions
Childs JL, Yates MD, Drake MA. Sensory properties of meal replacement bars and beverages made from whey and soy proteins. J Food Sci 2007;72(6): S425-434.
Veldhorst MAB, Nieuwenhuizen AG, Hochstenbach-Waelen A, van Vught AJAH, Westerterp KR, Engelen MPKJ, Brummer R-JM, Deutz NEP, Westerterp-Plantenga MS. Dose-dependent satiating effect of whey relative to casein or soy. Physiology & Behavior 2009;96(4-5): 675-682.
How much is needed?
Luhovyy BL, Akhavan T, Anderson GH. Whey proteins in the regulation of food intake and satiety. J Am Coll Nutr 2007;26(6): 704S-712S.
The qualities of whey protein • Overview • Biological value of whey protein – Nutritional value – Effect on diabetes – Exercise performance
• • • • •
Immunity Satiety Allergy Acne Conclusions
Szajewska H, Horvath A. Meta-analysis of the evidence for a partially hydrolyzed 100% whey formula for the prevention of allergic diseases. Current Medical Research and Opinion 2010;26(2): 423437.
Szajewska H, Horvath A. Meta-analysis of the evidence for a partially hydrolyzed 100% whey formula for the prevention of allergic diseases. Current Medical Research and Opinion 2010;26(2): 423-437.
Eczema
The qualities of whey protein • Overview • Biological value of whey protein – Nutritional value – Effect on diabetes – Exercise performance
• • • • •
Immunity Satiety Allergy Acne Conclusions
Acne and lactoferrin • • • •
Lactoferrin enriched fermented milk 200 mg of Lactoferrin/day 12 weeks 38.6% decrease in inflammatory lesions in Lactoferrin group compared to placebo group • Decreases in skin lipids in both groups Kim, J., et al., Dietary effect of lactoferrinenriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris. Nutrition, 2010. 26(9): p. 902-9.
Acne and Lactoferrin fermented milk
Kim, J., et al., Dietary effect of lactoferrin-enriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris. Nutrition, 2010. 26(9): p. 902-9.
Conclusions whey protein • Fast protein – Benefit in elderly – Possibly in clinical nutrition due to rapid absorption – Promotes muscle mass in sports
• Antidiabetic • Many reports on immunological benefit • Potential regulator of satiety • Few large randomized studies
