2012 38th Annual Northeast Bioengineering Conference (NEBEC 2012)

Philadelphia, Pennsylvania, USA 16-18 March 2012

IEEE Catalog Number: ISBN:

CFP12NEB-PRT 978-1-4673-1141-0

TABLE OF CONTENTS

Formal and De Facto Standards and Guidelines for Personal Health Records (PHRs) .................................................. 1 Pedro Gonzales, Binh Q. Tran

Assessing Traumatic Brain Injuries using EEG Power Spectral Analysis and Instantaneous Phase............................. 3 A. Napoli, K. Darvish, I. Obeid

Fabrication of Silicon Nanowires Field Effect Transistors for Biosensor Applications................................................... 5 Shi-Ya Hsu, Chia-Chang Tsai, Wen-Ti Hsu, Fu-Peng Lu, Jr-Hau He, Kuang-Hung Cheng, Shu-Chen Hsieh, HayYan Wang, Ying Sun, Li-Wei Tu

Relevance of PDMS Processing Techniques used in Electricity Generating Muscle Energy Converter........................ 7 Anisha Bapna

Home Healthcare Devices: Towards a Scalable, Portable, Accurate, and Affordable Data Acquisition Instrument.............................................................................................................................................................................. 9 M. Abdallah

The Effects of Functionallt Graded Structures on Contact Stress Distributions in Mental Hip Joints........................ 11 J. Clasrk, M. Ali, J. Hoffman, T. Kara, S. Takak

Instrumentation to Study the Influence of Attention on Disparity Vergence: Design of Novel Central and Peripheral Stimuli ........................................................................................................................................................ 13 Arieta Giokas, Bemin Ghobreal, Mayuri Kinkhabwala, Eun H. Kim, Yi Guo, Tara L. Alvarez

A Brain-Computer Interface for Robot Navigation.......................................................................................................... 15 Ahsan I. Nawroj, Siyuan Wang, Yih-Choung Yu, Lisa Gabel

Non-Invasive Compartment Syndrome Diagnosis ............................................................................................................ 17 A. Lepre, A. Zerdoum, C. Belfer, T. Kaverina

Amplitude Modulation Detection Patterns of the Budgerigar ......................................................................................... 19 Angela D. Ketterer, Douglas M. Schwartz, Kristina S. Abrams, Laurel H. Carney

Diffusion Tensor Tractography in Pediatric Spinal Cord................................................................................................ 21 Alani Intintolo, Nadia Barakat, Devon Middleton, Scott H. Faro, M. J. Mulcahey, Feroze B. Mohamed

Force Clamp and Electrical Stimulation on Decapod Appendages ................................................................................. 23 Aleksey Gladkov, Micheal Fagbote, Robert Hill, Ying Sun

An fMRI Investigation of a Memory Guided Vergence Task: Insights to the Parahippocampal Area........................ 25 Yelda Alkan, Paul A. Taylor, Bharat B. Biswal, Tara L. Alvarez

Interstitial Fluid Flow Increases Invasion of Ductal Carcinoma in Situ-like Cells Through PI3K-dependent Mechanisms ............................................................................................................................................. 27 A. M. Tchafa, A. C. Shieh

Performance Evaluation of the Activity Analyzer ............................................................................................................ 29 Harold Greene, Courtney Dulude, Amanda Neves, Ying Sun, Patricia Burbank

Environmental Chamber for Microscopic Observation ................................................................................................... 31 Max An, Danny Santucci, Caroline Wang, Benjamin Winter, A. Katz, C. Hall

Body Powered Anthropomorphic Prosthetic Hand with Force Feedback and Auto-Rotation Regimes ...................... 33 E. Anderson, J. Moloughney, K. Ozerinsky, R. Saleh

P300-based Brain-Computer Interface Memory Game to Improve Motivation and Performance.............................. 35 C. Angeloni, D. Salter, V. Corbit, T. Lorence, Y-C. Yu, L. A. Gabel

Characterization of Nanoparticle Distribution in Microcirculation: the Influence of Blood Cells and Vascular Geometry.............................................................................................................................................................. 37 Antony Thomas, Jifu Tan, Yaling Liu

Designing an Acoustics-Powered Automated External Defibrillator Battery Charger ................................................. 39 A. Parameswaran, S. J. Patel, R. V. Darji, A. Sorgi

Comparison of Spectroscopic and Biochemical Determination of Collagen Crosslinks in Cartilage ........................... 41 A. Hanifi, M. Terajima, M. Yamauchi, N. Pleshko

Interstitial Flow Drives CXCR4-dependent Hepatocellular Carcinoma Cell Invasion ................................................. 43 A. D. Shah, A. C. Shieh

High Magnification Imaging of Neuronal Somata Undergoing Axon Stretch Growth in Vitro ................................... 45 J. R. Loverde, B. J. Pfister

Low-power Fuzzy Logic VLSI Implementation with Asynchronous Topology for Neuronal Sensors......................... 47 B. I. Morshed, S. Consul-Pacareu

Custom Software for NJIT Flexible Visual Stimulator .................................................................................................... 49 Bemin Ghobreal, Eun H. Kim, Phillippe R. Moinot, Tara L. Alvarez

Table-Top Air Pressure-Driven Shock Tube to Induce a Blast Traumatic Brain Injury.............................................. 51 B. Swietek, V. Santhakumar, B. Pfister.

Prediction of Hot Spots of Ozone Flux in a Rhesus Monkey Lung During Steady Inspiratory Flow........................... 53 Banafsheh Keshavarzi, James S. Ultman, Ali Borhan

Needle Steering by Duty-Cycled Spinning: Modeling the Mechanics ............................................................................. 55 C. A. Lehocky, C. N. Riviere

Development of a Fourier Transform Infrared Imaging Spectroscopic Assay for Screening Estrogenic Contaminants .................................................................................................................................................... 57 C. M. Johnson, N. Pleshko, M. Achary, R. P. Suri

Mechanics of Aortic Valve Leaflet Mesostructures .......................................................................................................... 59 Christopher A Rock, Todd Doehring

V-Scope Extendable Intubation Stylet ............................................................................................................................... 61 C. Ekweghariri, C. Grunewald, T. Kramcha, M. Abdul Rahman, G. Atlas

Granger Causality Analysis Reveals the Changes of Thalamocortical Functionality after Cardiac Arrest Induced Hypoxic-Ischemic Injury.......................................................................................................................... 63 Cheng Chen, Anil Maybhate, Nitish V. Thakor

Transportable Infant Incubator for Developing Countries.............................................................................................. 65 R. Cichocki, R. O'Laughlin, A. Midouin, B. F. Busha

Understanding Alzheimer's disease with Network Biology.............................................................................................. 67 C. R. Kyrtsos, J. S. Baras

A Smartphone-Based Platform for Analyzing Physiological Audio Signals ................................................................... 69 Gary Comtois, John I. Salisbury, Ying Sun

Increasing the Quantity of Silver in Zinc-Based Glass Polyalkenoate Cement: Is there an Improvement in Antibacterial Efficacy? ........................................................................................................................... 71 A. Coughlan, S. M. Breed, C. Ashraf, J. A. Cardinale, M. M. Hall, M. R. Towler

Temperature-Field Reconstruction for the Application of Prostate Cryosurgery ......................................................... 73 C. V. Thaokar, Y. Rabin

The Effect of Preparation Procedures on the Interaction of Melanin with Ionizing Radiation .................................... 75 G. Lamberti, D. Reuther, S. A. Baranowitz, M. Kiani

Thermal Expansion of Cryoprotective Agents and Synthetic Ice Blockers .................................................................... 77 D. P. Eisenberg, Michael J. Taylor, Y. Rabin

Motion Correction Algorithms for Pediatric Spinal Cord Diffusion Tensor Imaging................................................... 79 Devon M. Middleton, Feroze B. Mohamed, Nadia Barakat, Louis N. Hunter, Jurgen Finsterbusch, Scott H. Faro, Pallav Shah, Amer Samdani, M. J. Mulcahey

Effect of Crosslinking and Glycosaminoglycan Depletion on the Extra-Fibrillar Matrix Mechanics of Annulus Fibrosus.......................................................................................................................................... 81 Daniel H. Cortes, Joseph Chiaro, Lachlan J. Smith, Dawn M. Elliott

Magnetic Resonance Elastography of Intervertebral Disc - A New Biomarker for Disc Degeneration ....................... 83 Daniel H. Cortes, Jeremy F. Magland, Alexander C. Wright, Victor H. Barocas, Dawn M. Elliott

Rapid Monitoring of Brain Auditory Evoked Potentials in Spontaneous Cerebral Hypoxia........................................ 85 Dmitry Khavulya, Jeffrey Tanedo, John K-J. Li

Cumulative Effect of Repeated Impacts on Lumbar Intervertebral Disc Mechanics: A Diurnal Cycle Study......................................................................................................................................................... 87 D. Jamison, C. J. Massey, M. A. Marcolongo

Quantitative Antibody Immobilization using Heteroand Homo-Bifunctional Crosslinkers for Analytical Biosensing........................................................................................................................................................... 89 D. R. Hansberry, P. M. Clark

Quantum Dot-Linked Immunoassay on a PMMA-Based Microfluidic Device for Biomarker Detection.................... 91 D. R. Hansberry, P. M. Clark

Designing a Wearable Computer for Lifestyle Evaluation............................................................................................... 93 Yicheng Bai, Chengliu Li, Yaofeng Yue, Wenyan Jia, Jie Li, Zhi-Hong Mao, Mingui Sun

3D/2D Model-to-Image Registration for Quantitative Dietary Assessment.................................................................... 95 Hsin-Chen Chen, Wenyan Jia, Zhaoxin Li, Yung-Nien Sun, Mingui Sun

Convenient Peripheral Blood Vessel Location via Differential Doppler Ultrasound: VEINUS.................................... 97 S. W. Blaise, S. J. Coyle, L. M. Mayer, M. J. Schurmann, D. Velez, J. T. Smok

A Novel Vacuum Assisted Scaffold System for Bony Regeneration ................................................................................ 99 D. Zhang, J. Santore, D. Wootton, S. M. Warren

Nanostructure-enhanced Proliferative Therapy for Ligaments and Tendons.............................................................. 101 Emmanuel C . Ekwueme, Yvonne M. Empson, Joseph W. Freeman

Quantification of Intervertebral Disc Cartilaginous Endplate Morphology using MRI ............................................. 103 E. E. Beattie, J. H. Yoder, S. M. Moon, E. J. Vresilovic, D. M. Elliott, A. C. Wright

Characterization of Drug Delivery Systems Utilizing Receptor-Mediated Transport................................................. 105 Erik Brewer, Anthony Lowman

Recovering Heart Sounds from Sparse Samples............................................................................................................. 107 Ervin Sejdic, Luis F. Chaparro

Biaxial Tensile Testing and Constitutive Modeling of Human Supraspinatus Tendon ............................................... 109 S. E. Szczesny, J. M. Peloquin, D. H. Cortes, J. Kadlowec, L. J. Soslowsky, D. M. Elliott

Development of a Maskless Microplasma Surface Patterning System for Biologics Printing..................................... 111 C. Wang, Q. Hamid, J. Snyder, H. Ayan, W. Sun

Application of a Virtual Trajectory to the Study of Rheumatoid Arthritis using the Pendulum Knee Test...................................................................................................................................................................................... 113 Ellexis Cook, Vrushali A. Shedage, Richard Foulds

On Detecting and Adaptive Timing for Electromyogram Based Control Signals........................................................ 115 Evan Lum, Christian Perez, Ying Sun

Mesenchymal Stem Cell Death in Three-Dimensional Agarose Culture for Cartilage Tissue Engineering Applications: Progression, Factors, and Prevention ................................................................................. 117 M. J. Farrell, K. M. Farrell, C. N. Riggin, R. L. Mauck

Normal Force Estimation using Tactile Imaging Sensor................................................................................................ 119 Firdous Saleheen, Amrita Sahu, Vira Olekshyuk, Chang-Hee Won

Innovative Total Knee Arthroplasty Removal System ................................................................................................... 121 C. Alecci, E. Boosmann, F. Kipcakli, A. Mayorga, J. Payumo, A. Siebenhuhner

Telemanipulation using Exact Dynamics iARM ............................................................................................................. 123 Bemin Ghobreal, Arieta Giokas, Frandy Dort, Amish Gandhi, Richard Foulds

Organized Nanofibrous Scaffolds to Mimic the Macroscopic Curvature of the Meniscus.......................................... 125 M. B. Fisher, E. A. Henning, J. L. Esterhai, R. L. Mauck

Vaginal Delivery Disrupts Vaginal Smooth Muscle (VaSM) Contraction .................................................................... 127 Z. C. Jallah, P. A. Moalli, S. D. Abramowitch

Influences of Structural Properties of the Distal Tibia on the Compressive Strength of Interlocking Screws for Intramedullary Nails ...................................................................................................................................... 129 F. Xavier, E. Goldwyn, A. Carrer, R. Elkhechen, W. Hayes, S. Saha

Improving the Binding Efficiency of a Vascular Drug Delivery System by using a Dual-receptor Targeting Strategy ............................................................................................................................................................. 131 G. Lamberti, M. F. Kiani, B. Wang

Assessment of Passive Knee Stiffness and Set Point ....................................................................................................... 133 Ghaith J. Androwis, Darnell Simon, Richard A. Foulds

Neuron Emulation, Instrumentation, and Communication for a Neuroscience Instrument....................................... 135 Gabriel Ausfresser, Ying Sun

Effect of Deformation Rate on the Flexural Strength of Human Ribs .......................................................................... 137 G. Feuer, S. Saha

Environmental Uses for Bovine Collagen Nanofibrils .................................................................................................... 139 K. M. Tschinkel , G. J. Maffia

Toward Robot-Assisted Stapes Fenestration with a Handheld Micromanipulator ..................................................... 141 G. Montes Grande, A. J. Knisely, B C. Becker, S. Yang, B. E. Hirsch, C. N. Riviere

Determining Significance in Metagenomic Samples ....................................................................................................... 143 Gregory Ditzler, Robi Polikar, Gail Rosen

Drug Adhesion Parallel Plate Flow Chamber ................................................................................................................. 145 G. Han, K. Hardiman, R. Hyer

Micro-scale Strain Transfer in Fiber-Reinforced Native Tissues and Cell-Seeded Aligned Nanofibrous Scaffolds ............................................................................................................................................................................. 147 W. M. Han, S. J. Heo, T. P. Driscoll, R. L. Mauck, D. M. Elliott

A New Approach For Mixture Separation Using NMR Spectroscopy: Blind Iterative Source Identification ...................................................................................................................................................................... 149 Hasan Celik, Athan J. Shaka

FEM-predicted Regional Tissue Strains Aligned with the White Matter Tracts Predict Axonal Injury................... 151 S. K. Hashmi, S. Sullivan, S. A. Eucker, B. Coats, J. Lee, S. S. Margulies

Development of a Remote Pupillometer System for Non-Invasive, Distant Analysis................................................... 153 Harold Hovagimian, Christopher Walker, Domhnull Granquist-Fraser, John Turkovich

Effects of Dynamic Tensile Loading on TGF and BMP Signaling Pathways in Mesenchymal Stem Cells on Aligned Nanofibrous Scaffolds........................................................................................................................... 155 S. J. Heo, T. P. Driscoll, R. L. Mauck

Semi-Automatic 3D Construction of Liver using Single View CT Images.................................................................... 157 Hersh J. Parmar, S. Ramakrishnan

Sleep Apnea Diagnosis via Single Channel ECG Feature Selection .............................................................................. 159 H. Guruler, M. Sahin, G. Ordek, A. Ferikoglu

The Acid-based Properties of Carboxylated CNT and the Design of CNT based Biosenor ........................................ 161 Hyuk Je Kwon, Jun-Myung Woo, Jaeheung Lim, Seok Hyang Kim, Young June Park

On Improving the Deformation and Display Modules of Surgery Simulation Systems............................................... 163 Rui Hu, Kenneth Barner, Jingyi Yu, Karl Steiner

Electronic Model of Synaptic Transmission .................................................................................................................... 165 Felix Hutchison

Modal Analysis of a Spreading Osteoblast Cell in Culturing......................................................................................... 167 Hwabok Wee, Arkady Voloshin

Foot and Ankle System Identification with Black Box Models ...................................................................................... 169 Hwabok Wee, Arkady Voloshin

Effect of Model Microgravity on Human Hepatic Pharmacokinetics and Urea Secretion.......................................... 171 J. E. Snyder, K. Emami, B. Du, Y. Zhang, H. Wu, W. Sun

Developing the Cryomacroscope for Cryopreservation Applications ........................................................................... 173 Justin S. G. Feig, Alexander C. Williams, Christopher C. Lin, Yoed Rabin

Assemble Single Stranded DNA and Gold Nanoparticle Complexes onto the Surface of RBC .................................. 175 Jia Hu, Antony Thomas, Kyle Selditch, Yaling Liu

A Multiphase Model for Nanoparticle Delivery in Microcirculation ............................................................................ 177 Jifu Tan, Antony Thomas, Yaling Liu

Dissipation of High Impact Forces to Enhance Safety of Hockey Gloves ..................................................................... 179 B. Wang, C. Tucci, J. Mathew, T. Mirza

Combined Ultrasound and Transrectal Electrical Impedance Imaging of the Prostate.............................................. 181 Y. Wan, R. Halter, J. Heaney, J. Seigne, A. Schned, A. Borsic, A. Hartov

Role of the Cognitive Influence of Familiarity in Processing Kinetic-Depth-Effect Signals........................................ 183 Jordan T. Ash, James M. Hughes, Thomas V. Papathomas

Selenium Nanoparticles for the Prevention of PVC-related Medical Infections .......................................................... 185 J. F. Ramos, P. A. Tran, T. J. Webster

A Methodology of Measuring Coronary Flow in a Porcine Aortic Root Using a Pulsatile Flow Loop....................... 187 Joe Calderan, Eric Sirois, Wei Sun

Determination of Radial Force and Coefficient of Friction with a Self-Expanding Transcatheter Aortic Valve Stent.............................................................................................................................................................. 189 Joseph Mummert, Andrew Reynolds, Eric Sirois, Wei Sun

Characterization of Flagella-Templated Silica Nanotubes and Their Metallization.................................................... 191 W. Jo, K. J. Freedman, M. J. Kim

Histone Methylation as a Marker of Chondrocyte Phenotype....................................................................................... 193 J. Wang, S. L. Kummer, M. S. Cosgrove, J. H. Henderson

Temporally Resolved Imaging of Ice Nucleation and Growth in Highly Supercooled Water..................................... 195 John P. McCloskey, Jens O. M. Karlsson

Towards the Optimal Design of an Assistive Communication Interface with Neural Input ....................................... 197 Kathryn Tringale, Daniel Bacher, Leigh Hochberg

Local Material Properties of Human Aorta under Dynamic Biaxial Loading ............................................................. 199 G. Kermani, K. Darvish

Material Properties of Different Layers of Aorta ........................................................................................................... 201 A. Hemmasizadeh, M. Autieri, K. Darvish

Supracondylar Femoral Fracture Fixation: Locked Plating Versus Retrograde Nailing ........................................... 203 Soroush Assari, Alan Kaufmann, Kurosh Darvish, Saqib Rehman, Jung Park, Jonathan Haw, Fayez Safadi

Investigating the Effects of Dynamic and Static Loading on the Stability of Porcine Aorta....................................... 205 Kaveh Laksari, Mobin Rastgar Agah, Alexander Rachev, Kurosh Darvish

Improved Locomotion for the HeartLander Robot for Injection of an Anti-Remodeling Hydrogel.......................... 207 Kevin Fok, Nathan A. Wood, Cameron N. Riviere

Quadriceps Muscle Geometry Differs Between Healthy Individuals and those with Post-stroke Hemiparesis........................................................................................................................................................................ 209 Kevin G. Pineault, John W. Ramsay, Jill S. Higginson

Optimization of Macromer Density in Human MSC-Laden Hyaluronic Acid (HA) Hydrogels ................................. 211 M. Kim, S. Garrity, I. E. Erickson, A. H. Huang, J. A. Burdick, R. L. Mauck

New Biomimetic Aggrecan for Treatment of Intervertebral Disc Degeneration.......................................................... 213 D. Madende, K. Prudnikova, S. Lightfoot, E. Vresilovic, M. Marcolongo

Use of Genipin to Crosslink Lyophilized Matrices Made from Collagen Nanofibrils.................................................. 215 K. M. Scherpf, G. J. Maffia

Platelet Generation Under Shear Force Modulated by Site-Specific Phosphorylation of Myosin-IIA Heavy Chain....................................................................................................................................................................... 217 Kyle Spinler, Jae-Won Shin, Dennis E. Discher

Automated Delineation of Pulmonary Artery Cross-Sections in CT Scans .................................................................. 219 Kyle Rafferty, Ying Sun, Tzu-Chao Chuang, Ming-Ting Wu

Development of an Activity Analyzer with Voice Directions for Exercises................................................................... 221 Kyle Rafferty, Timothy Alberg, Harold Greene, Gabriel Ausfresser, Ying Sun, Patricia Burbank

Calcium Signaling of Chondrocytes under Osmotic Stress and Mechanical Stimulation ........................................... 223 Wen Li, Miri Park, Catherine Kirn-Safran, Liyun Wang, X. Lucas Lu

Gallium Containing Glass Polyalkenoate Bone Cements: Glass Characterization and Physical Properties ........................................................................................................................................................................... 225 L. Placek, A. W. Wren, A. Coughlan, M. R. Towler

A Programmable Shape-Changing Scaffold for Regenerative Medicine ...................................................................... 227 Ling-Fang Tseng, Patrick T. Mather, James H. Henderson

Nanophase Magnesium for Orthopedic Applications..................................................................................................... 229 L. Weng, D. A. Stout, T. J. Webster

Seizure Detection in EEG Signals Using Support Vector Machines.............................................................................. 231 Cher Hau Seng, Ramazan Demirli, Lunal Khuon, Donovan Bolger

A Multi-Modality Sensor Platform Approach to Detect Epileptic Seizure Activity..................................................... 233 Sai R. Gouravajhala, Lunal Khuon

Design of a Capsule Endoscopy Device Less Susceptible to Tumbling.......................................................................... 235 A. W. Polivy, S. A. Marion, S. L. Firebaugh, A. Duttaroy, R. Pais

Estimation of Cardiovascular Parameters From ECG And PPG Signals .................................................................... 237 P. Manimegalai, Delpha Jacob, K. Thanushkodi

Analysis of Pressure Wave to Determine the Augmentation Index for Preventing Premature Death ....................... 239 J. Depha, K. Thanushkodi

Cyclic Stretch Induced Oxidative Injury Increases Alveolar Permeability via ERK-NF-kB Signaling..................... 241 N. Davidovich, B. C. Dipaolo, G. G. Lawrence, P. Chhour, N. Yehya, S. S. Margulies

Rat Precision-cut Lung Slices as a Model for Deformation-induced Lung Injury Studies.......................................... 243 J. Huang, N. Davidovich, S. S. Margulies

Non-Invasive Neonatal Vital Acquisition Unit ................................................................................................................ 245 M. Mastro, M. Bunalski, B. F. Busha

A Contour-Based Particle Tracking System for the Study of Cell Migratory Behavior.............................................. 247 M. E. Brasch, R. M. Baker, M. I. Manning J. H. Henderson

Mechanical Stimulation Device for Skeletal Muscle Tissue Engineering...................................................................... 249 M. C. McCorry, C. Ohlson, S. Gunnel, S. Higginbottom, K. Billiar, R. Page

Systematic Nanoparticle Diffusivity Estimation Using Multicellular Tumor Spheroid Model................................... 251 Mohammed Shahid, Sunaina Arshad, Minru Hwang, Pratik K. Patel, Elaine Y. Yu, Charles M. Roth

Role of Dimensionality on Spinal Cord Dendrites .......................................................................................................... 253 M. L. Previtera, A. J. Shahin, R. Kleiman, R. Schloss, N. A. Langrana

Role of Inflammatory Pathway and Cells on Glioma Cell Response to Chemotherapy .............................................. 255 Molly J. Carroll, Leora Nusblat, Charles M. Roth

Frequency Spectrum Relationship with Vascular Disease Growth in Stenosis Model ................................................ 257 Monica Rodas, Gary Drzewiecki

Laparoscopic Manipulator with Haptics Force Feedback ............................................................................................. 259 E. Hesselbacher, A. Kilayko, M. Russell, J. Varbanov

Viability of Harvesting Stem Cells from Adipose Tissue using an Ultrasonically Assisted Method ........................... 261 Mark E. Schafer, Kevin Hicok

Ceiling Canopy for Hybrid Cardiac Operating Room ................................................................................................... 263 L. Daly, A. Duran, L. Giannechini, S. Parker, M. Walker

Fructose Enhanced Reduction of Bacterial Growth on Nanorough Surfaces without using Antibiotics ................... 265 N. Gozde Durmus, Erik N. Taylor, Kim M. Kummer, Thomas J. Webster

Adjustable Rollator with Dual Brake System to Enhance Stability .............................................................................. 267 K. Bolante, N. Carrillo, H. Tang, T. Takahashi

Medical Devices and Biomaterials for the Developing World: Technical Solutions and Policy Recommendations.............................................................................................................................................................. 269 Olumurejiwa A. Fatunde, Sujata K. Bhatia

Study of Material Process Compatibility for a Hybrid Tissue Scaffold Formation System ........................................ 271 James Ferrie, Kevin Froster, Timothy Olsen, Raj Vansia, Christopher Anderson, Karen Chang Yan

Leptin Inhibitor as a Novel Therapeutic for Osteoarthritis........................................................................................... 273 Padma Pradeepa Srinivasan, Xinqiao Jia, Randall L Duncan, Catherine Kirn Safran

Genipin Crosslinked Polysaccharide Hydrogels as Rheologically Enhanced Osteoblast Growth Substrates ........................................................................................................................................................................... 275 V. Pandit, S. P. Kotha

Rehabilitative Arm Assist Device ..................................................................................................................................... 277 C. Paparella, D. Molina, C. Mejia, G. Van Ness, A. Levitsky, J. Wang, C. Hall

Power Based Analysis of Single-Electrode Human EEG Recordings Using Continuous Wavelet Transform .......................................................................................................................................................................... 279 Parham Ghorbanian, David M. Devilbiss, Adam J. Simon, Hashem Ashrafiuon

Dielectrophoretic Tweezers as a Platform for Molecular Force Spectroscopy in a Highly Parallel Format ................................................................................................................................................................................ 281 Peng Cheng, Michael J. Barrett, Piercen M. Oliver, Deniz Cetin, Dmitri Vezenov

A Model for Intervertebral Disc Shape Variation in a Population Including the Effect of Degeneration ................. 283 J. M. Peloquin, J. H. Yoder, N. T. Jacobs, S. M. Moon, A. C. Wright, E. J. Vresilovic, D. M. Elliott

Anodized Microporous and Nano Structured Ti-6Al-4V for Increasing Bone Cell Functions ................................... 285 A. P. Ross, T. J. Webster

Silver Coated Bioactive Glass Particles for Wound Healing Applications.................................................................... 287 P. Hassanzadeh, A. W. Wren, M. R. Towler

Layer-by-layer 3-D Constructs of Adherent and Nonadherent Cells in Hydrogel....................................................... 289 T. B. Phamduy, N. Abdul Raof, Y. Xie, D. B. Chrisey

Examination of the Migratory Potential of Patterned Cortical Neurons using Laser Direct-write............................ 291 T. B. Phamduy, C. J. Rivet, D. Kingsley, R. J. Gilbert, D. B. Chrisey

In Vitro 3-D Culture Model of Tumor Cell Compression .............................................................................................. 293 P. Tomezsko, D. Kyryliouk, P. Sharma, A. Morgano, A. Shieh

Compressive Sensing for ECG Signals in the Presence of Electromyographic Noise .................................................. 295 Luisa F. Polania, Rafael E. Carrillo, Manuel Blanco-Velasco, Kenneth E. Barner

Control of the Inflammatory Response with Poly(trolox ester) Antioxidant Nanoparticles ....................................... 297 Patricia Wardwell, Paritosh Wattamwar, Thomas Dziubla, Rebecca Bader

Integrating Kinematic Modeling and Kinetics to Quantify Hand Motor Performance in Persons with Stroke.................................................................................................................................................................................. 299 Saumya Puthenveettil, Qinyin Qiu, Gerard Fluet, Sergei Adamovich

A Digital Micro-mirror Device-based System for the Fabrication of Microfluidic Tissue Array............................... 301 Q. Hamid, C. Wang, J. E. Snyder, W. Sun

Matrices Engineered with Gradients in Rigidity Guide Stem Cell Migration and Polarize the Cytoskeleton....................................................................................................................................................................... 303 M. D. Raab, J. Swift, D. E. Discher

Fourier Transform Infrared Imaging Spectroscopy of Collagen Deposition after Myocardial Infarction............................................................................................................................................................................ 305 R. Cheheltani, B. Wang, A. Sabri, N. Pleshko, M. Kiani

Pressure Analysis of the Blood Flow in the Arteriole ..................................................................................................... 307 Hansol Chung, David Bahk

Poly(caprolactone) Shape Memory Scaffold for Bone Tissue Engineering................................................................... 309 R. M. Baker, J. H. Henderson, P. T. Mather

Interactions of Fluorescein Isothiocyanate-labeled Poloxamer P188 with Cultured Cells .......................................... 311 Raha M. Dastgheyb, Michael C. Cochran, Kenneth A. Barbee

Combined Electromyography(EMG)-driven Robotic System with Functional Electrical Stimulation (FES) for Rehabilitation.................................................................................................................................................... 313 W. Rong, K. Y. Tong, X. L. Hu, N. S. K. Ho

A Model System for Determining Blastocyst Binding Mechanics.................................................................................. 315 R. W. Yucha, M. Jost, N. Robertson, M. Marcolongo

Molecular Modeling of Membrane Curvature Driven by Epsin ................................................................................... 317 Ryan Bradley, Ravi Radhakrishnan

Designing Android Applications with both Online and Offline Voice Control of Household Devices ....................... 319 Stephanie Barrena, Laura Klotz, Vanessa Landes, Alex Page, Ying Sun

Mechanical Characterization of Corn-Derived Poly-L-Lactic Acid.............................................................................. 321 Leslie A. Rea, Sujata K. Bhatia

An Introductory Short Course in Biochemical and Biomedical Engineering for Undergraduate Students .............................................................................................................................................................................. 323 Sujata K. Bhatia

Risk of Aortic Dissection Due to Aortic Curvature and Malignant Hypertension....................................................... 325 Simran Sahni, Sujata K. Bhatia

Neuronal Recorder Implementation With Envelope Detector for Fidelity and Linearity........................................... 327 S. Consul-Pacareu, B. I. Morshed

Derivation and Development of a Mathematical Model for Long Bone Growth ......................................................... 329 Suneil R. Seetharam, Sujata K. Bhatia

Application of a Mathematical Model for Long Bone Growth ...................................................................................... 331 Suneil R. Seetharam, Sujata K. Bhatia

Design Proposal for a Microfluidic Device for Sprouting Angiogenesis........................................................................ 333 M. A. Calt, M. K. Sempkowski, R. Lamba, S. Ahlawat, C. Anderson

Determining the Minimum Number of Thin-Film Force Sensors Required to Represent Actual Hand Grip Forces......................................................................................................................................................................... 335 S. V. Tornifoglio, D. R. Peterson

Modification of a Direct Perfusion Bioreactor for Evaluation of SaOS-2 Cell Response to Multiple Ceramic Bone Graft Substitutes in Vitro......................................................................................................................... 337 S. K. Sheth, J. F. Bilikiewicz, D. S. Clearfield, D. Dymarsky

Tri-axial Electro-goniometer for Spinal Mption ............................................................................................................. 339 K. Killen, S. Music, J. Zielinska

Literary Enhancement and Physical Therapy Among Children Using Robotics......................................................... 341 Savan Patel, Lisha Malkani, Adrian Celiz, Tanay Shah, Bryan Pfister

Electrically Conductive, Biocompatible Composite Containing Carbon Nanobrushes for Applications in Neuroregeneration......................................................................................................................................................... 343 Erfan Soliman, Sze C. Yang, George W. Dombi, Sujata K. Bhatia

Biosensors of ZnO Nanotetrapods and HEMT for Detecting Uric Acid ....................................................................... 345 Yu Song, Yang Lei, Kiaoqin Yan, Yue Zhang, Yaling Liu

Comparison of Whole-Brain to Region-Based fMRI Analyses ...................................................................................... 347 Rohit Saigal, Yelda Alkan, Bharat B. Biswal, Tara L. Alvarez

Computer Assisted Analysis of Left Ventricle using Level Set and Enhanced Filtering in Cardiac MRI ................. 349 R. Sreemathy, Rekha S. Patil

Simultaneous Calibration of Stereo Vision and 3D Optical Tracker for Robotic Microsurgery................................ 351 S. Rodriguez Palma, B. C. Becker, C. N. Riviere

Wideband Voltage Source Design for EIT Systems ........................................................................................................ 353 T. R. Qureshi, B. Mehboob, C. R. Chatwin, W. Wang

Design of a Mechanical CPR Device: Automated CPR To-Go (ACT) .......................................................................... 355 T. Habibian, A. Mehta, A. Harr, L. Hernandez

Interaction of a Percutaneous Ventricular Assist Device with the Cardiovascular System ........................................ 358 Nicole Tchorowski, Yih-Choung Yu

Gait Analysis and Spinal Rotation ................................................................................................................................... 360 Tom Fontecchio

The Structural Characterization of Ga2O3-Na2O-CaO-ZnO-SiO2 Bioactive Glasses .................................................. 362 T. J. Keenan, A. W. Wren, A. Coughlan, M. M. Hall, M. R. Towler

Force Sensing Syringe as a Teaching Tool for Injection ................................................................................................ 364 Tyler M. Ridwout, John R. Lacourse, Paula L. McWilliam

Mesoscale Simulations of Curvature Inducing Protein Partitioning in the Presence of Mean Curvature Gradients ......................................................................................................................................................... 366 R. Tourdot, J. Liu, R. Radhakrishnan

Dynamic Loading and Altered Contractility Modulate Nuclear Deformation and Nesprin Expression.................... 368 Tristan P. Driscoll, Su-Jin Heo, Robert L. Mauck

Near Infrared Spectroscopic Evaluation of Water in Hyaline Cartilage ...................................................................... 370 M. Padalkar, R. Spencer, N. Pleshko

Comparison of Histological Grading to Fourier Transform Infrared Imaging Analysis of Cartilage Repair Tissue ..................................................................................................................................................................... 372 M. P. O'Brien, M. Penmatsa, U. Palukuru, P. West, X. Yang, M. P. G. Bostrom, T. Freeman, N. Pleshko

Identification of Markers Specific to Low-dose Radiation in Human Endothelial Cells ............................................. 374 P. Mohan Achary., D. T. Teka, A. Jhaveri, G. Lamberti, P. Pandian, K. Pant, M. F. Kiani

Analysis of Trabecular Structure in Radiographic Bone Images using Empirical Mode Decomposition and Support Vector Machines .......................................................................................................................................... 376 G. Udhayakumar, C. M. Sujatha, S. Ramakrishnan

Development of a Chemically Crosslinked Poly(vinyl alcohol) Hydrogel for Injectable Nucleus Pulposus Replacement....................................................................................................................................................... 378 V. R. Binetti, M. Marcolongo, A. M. Lowman

Coaxial Electrospinning of Gelatin/Polyvinyl Alcohol Composite Nanofibers and Evaluation of Their Material Properties............................................................................................................................................................ 380 Valerie Merkle, Xiaoyi Wu

A Fiber Optic Enhanced Bone Biopsy Needle ................................................................................................................. 382 Jeff Misiewicz, Bao Nguyen, Ashu Poudyal, Kelliann Wachrathit Yu Chen, Jafar Vossoughi

A Motorized Power Glider................................................................................................................................................ 384 E. C. Benoy, V. Desai, A. R. Gandhi, V. Vehseli

An Event Classifier using EEG Signals: an Artificial Neural Network Approach....................................................... 386 Ahsan Nawroj, Siyuan Wang, Ismail Jouny, Yih-Choung Yu, Lisa Gabel

Portable Amplifier Design for a Novel EEG Monitor in Point-of-Care Applications.................................................. 388 Bo Luan, Mingui Sun, Wenyan Jia

A Non-Contacting Sensor to Measure the Stress Wave Generated Magnetic Field in Bone: A Preliminary Study.............................................................................................................................................................. 390 W. T. Hayes, J. N. Carter, G. Feuer, S. Saha

Translational Potential for Hydrogel Composites Containing Carbon Nanobrushes.................................................. 392 William H. Marks, Sze C. Yang, George W. Dombi, Sujata K. Bhatia

Biomimetic Hydrogels for Tissue Engineering of the Intervertebral Disc .................................................................... 394 C. T. Wiltsey, T. R. Christiani, J. Williams, J. L. Coulter, D. N. Demiduke, K. A. Toomer, S. M. English, B. A. Hess, A. M. Branda, J. Sheehan, J. A. Kadlowec, T. Tulenko, C. Iftode, A. J. Vernengo

Painful Whole Body Vibration Increases NGF & BDNF in Cervical Intervertebral Discs in the Rat ....................... 396 J. L. Branconi, B. B. Guarino, H. A. Baig, B. A. Winkelstein

Biomechanical Effects of Whole Body Vibration on Spinal Ligaments: A Potential Mechanism of Tissue Damage ................................................................................................................................................................... 398 B. R. Freedman, H. A. Baig, B. B. Guarino, B. A. Winkelstein

Repeated Whole-Body Vibration Exposure Induces Prolonged Mechanical Hyperalgesia & Increased Spinal COX-2: A Novel Rat Model .................................................................................................................................. 400 B. B. Guarino, H. A. Baig, J. L. Branconi, B. A. Winkelstein

The Transmissibility Response of the Rat During Whole Body Vibration Along its Long-Axis................................. 402 H. A. Baig, B. B. Guarino, N. V. Jaumard, B. A. Winkelstein

The Rat as a Viable Model for Human Cervical Biomechanics: A Quantitative Anatomy Study .............................. 404 A. J. Gokhale, B. B. Guarino, B. A. Winkelstein

Enhanced Osteoblast Adhesion on Novel Biomimetic Nanotube/Nanoparticle Coating for Orthopedic Applications........................................................................................................................................................................ 406 Mian Wang, Jian Li, Lijie Grace Zhang, Michael Keidar

Hyaluronic Acid-based Hydrogels as 3D Matrices for in Vitro Tumor Engineering................................................... 408 Xian Xu, Xinqiao Jia

Vocal Fold-Mimetic Environment for Fibroblastic Differentiation of Mesenchymal Stem Cell................................. 410 Zhixiang Tong, Xinqiao Jia

In-situ Biofabrication of Stratified Biofilm Mimics for Direct Observation of Bacterial Signaling ........................... 412 X. L. Luo, H. C. Wu, C. Y. Tsao, Y. Cheng, G. W. Rubloff, W. E. Bentley

Segmentation of Hippocampus and Amygdala Using Multi-channel Landmark Large Deformation Diffeomorphic Metric Mapping........................................................................................................................................ 414 Xiaoying Tang, Susumu Mori, Tilak Ratnanather, Michael I. Miller

Micro-patterned Surface for Efficient Capturing of Circulating Tumor Cells ............................................................ 416 Antony Thomas, Chi-Mon Chen, Shu Yang, Xuanhong Chen, Yaling Liu

Targeted Delivery of Vascular Endothelial Growth Factor to Enhance the Stem Cell Therapy in Treating Myocardial Infarction in Rats........................................................................................................................... 418 Yuan Tang, Elizabeth Curran, Mohammad F. Kiani, Bin Wang

An In Vitro 3-D Model of Collagen-Based Fiber Constituents for Peripheral Nerve Conduits.................................. 420 M. L. Siriwardane, K. E. Derosa, G. L. Collins, B. J. Pfister

Complexation Hydrogels for Stabilization of Peptidic HIV-1 Virucides....................................................................... 422 P. L. Kubinski, A. M. Lowman, P. L. Kubinski, C. Duffy, M. R. Contarino, I. Chaiken

Distortion Correction in Wide-Angle Images for Picture-Based Food Portion Size Estimation................................. 424 Zhaoxin Li, Mingui Sun, Hsin-Chen Chen, Jie Li, Kuanquan Wang, Wenyan Jia

Anthropometric Measurements from Multi-View Images ............................................................................................. 426 Jie Li, Mingui Sun, Hsin-Chen Chen, Zhaoxin Li, Wenyan Jia

Relay Effect on Wireless Power Transfer using Resonant Coupling............................................................................. 428 Hao Wang, Zhi-Hong Mao, Qi Xu, Mingui Sun

Drowsiness Control Center by Photoplythesmogram..................................................................................................... 430 Yichao Joy Xu, Fangjie Ding, Zhongjie Wu, Jun Wang, Quanquan Ma, Ki Chon, Edward Clancy, Michael Qin, Yitzhak Mendelson, Ningxin Fu, Sinan Assad, Susan Jarvis, Xinming Huang

Investigating the Hyperelasticity of Porcine Aorta under Sub-failure Loading........................................................... 432 Mobin Rastgar Agah, Kaveh Laksari, Kurosh Darvish

Effect of Contact Angle on the Morphology of Different Polymer-solvent Systems Produced by AAO Templates ........................................................................................................................................................................... 434 P. Li, H. Xu, M. Li Sing How, S. Shivkumar

Compositional and Mechanical Properties of Long Bones of Osteoactivin Mutant Mice ........................................... 436 Y. Ou, J. Y. Belcher, V. R. Yingling, F. Safadi, N. Pleshko Author Index