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Studies on cardiac pacing : emphasis on pacemaker sensors and cardiac resynchronization therapy Erol-Yilmaz, A.

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Citation for published version (APA): Yilmaz, A. (2005). Studies on cardiac pacing : emphasis on pacemaker sensors and cardiac resynchronization therapy Amsterdam: Amsterdam University Press

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Download date: 18 Jan 2017

Cerebrall bloodflowvelocity and cardiacc output at the onset of dynamicc exercise at two settings of pacemakerr determined heart rate

Aytenn Erol-Yilmaz MD1, Lysander W.J. Bogert MD,2 Raymond Tukkie MD PhD1, Arthur A.. Wilde MD PhD1. Wouterr Wieling MD PhD 2 and Johannes J. van Lieshout MD PhD 2

Clinicall and Experimental Cardiology1, Department of Internal Medicine2. Academicc Medical Center. Amsterdam, The Netherlands. Dr.. Erol-Yilmaz and Dr. Bogert contributed equally to the article

SubmittedSubmitted for publication

Abstract t Background d Inn cardiac patients, the increase in the transcranial Doppler determined middle cerebrall artery (MCA) mean flow velocity (V mean ) during exercise depends on the abilityy to increase cardiac output (Q), The aim of this study was in six patients (66 (49-76)) yr.) with complete heart block and ventricle rate adaptive pacemakers to evaluatee whether variation in heart rate (HR) affects the increase in MCA V m e a n and OO during exercise.

Materialss and methods Thee effect of setting the pacemaker to "default" (DSS) vs. "optimized" (OSS) on bloodd pressure (BP).Q, stroke volume (SV1 and MCA V m e a n was evaluated during gradedd ergometry cycling. During the first 3 min. of exercise in OSS vs. DSS at 25 andd 75 W the rise in HR (26 (1-59) vs. 13 (0-25) bpm; P

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