NDT Plus (2008) 3: 157–161 doi: 10.1093/ndtplus/sfn012

Case Report

Rhabdomyolysis after ezetimibe/simvastatin therapy in an HIV-infected patient Noemie Chanson1 , Philippe Bossi2 , Luminita Schneider2 , Edward Bourry1 and Hassane Izzedine1 Departments of 1 Nephrology and 2 Infectious Diseases, Pitie-Salpetriere Hospital, Paris, France

Keywords: drug–drug interaction; HIV infection; rhabdomyolysis; statin

Case report A 42-year-old white man was admitted to hospital with a 3-day history of progressive muscle weakness, myalgias and dark urines. He was HIV/hepatitis C virus (HCV) coinfected, with an absolute CD4+ T lymphocyte count of 393 cells/mm3 , a serum HIV-1 RNA load of