Research Interests, Publications and Presentations Dr. Mahroof-Tahir’s research group is involved in synthesis and characterization of vanadium complexes with promising antidiabetic properties. These complexes are characterized by using instrumental techniques like NMR, IR, UV-vis, and GC-MS. We characterize these complexes in a solution state to get an insight into the active species with antidiabetic properties. We are also working on understanding the mechanistic and structure activity relationship (SAR) studies in which complexes are synthesized with systematic variations in their structures. These complexes are tested for their enzyme inhibition properties with three key enzymes, protein tyrosine phosphatase, alpha glucosidase and phosphodiasterase, which play an important role in diabetes. His research group is also involved in synthesis and characterization of anticancer complexes of titanium and germanium. The studies of the interaction of these complexes with DNA are carried out by using NMR spectroscopy and other instrumental techniques to understand the mechanism and action of these complexes. The anticancer properties and enzyme inhibition studies of these complexes are carried out in my collaborators’ laboratories. PUBLICATIONS, PRESENTATIONS AND SEMINARS: Publications in Peer Reviewed Journals: 1.

Mahroof-Tahir, M.; Wenz, D.; Gregory, D., “Synthesis, characterization, radical scavanging properties and computational strcutural elucidation of vandium-flavonoid complexes”, manuscript in preparation.

2.

Bushkofsky, J.; Gregory, D.; Mahroof-Tahir, M., “Synthesis and Characterization of Vanadium Flavonoid Complexes”, manuscript in preparation.

3.

Qurrat Ul Ain, Uzma Ashiq, Rifat Ara Jamal, Mohammad Mahroof –Tahir, Zara Shaikh, Synthesis, structural and radical scavenging studies of Palladium(II)-hydrazide complexes, submitted to J. of Coordination Chemistry

4.

Karimov, K. S.; Saleem, M.; Mahroof-Tahir, M.; Qasuria, T.A., Khan, A.; Khan, T.A., “Displacement-sensitive organic field effect transistor,” International Journal of Electronics, 2012, 99, 91-101

5.

Karimov, Kh. S.; Mahroof-Tahir, M.; Saleem, M.; Ahmad, Z., “I-V Characteristics of Vanadiumflavonoid complexes based Schottky diodes", Physica B, 2011, 406, 3011–3017.

6.

Karimov, Kh. S.; Abid, M.; Mahroof-Tahir, M.; Saleem, M.; Khan, A.; Karieva, Z. M.; Farooq, M., “V2O4–PEPC composite based pressure sensor,” Microelectronic Engineering, 2011, 88, 10371041.

7.

Ahmad, Z.; Sayyad, M. H.; Yaseen, M.; Aw, K. C.; Mahroof-Tahir, M.; Ali, M., “Potential of 5,10,15,20-Tetrakis(3,5-di-tertbutylphenyl)porphyrinatocopper(II) for amultifunctional sensor,” Sensors and Actuators B: Chemical, 2010, 155, 81-85.

8.

Karimov, Kh. S.; Saleem, M.; Mahroof-Tahir, M., Khan, T.A., Khan, A., "Pressure Sensitive Organic Field Effect Transistor," Physica E, 2010, 43, 547-551.

9.

Murtaza, I.; Karimov, K.; Ahmad, Z.; Qazi, I.; Mahroof-Tahir, M.; Khan, T. A., “Humidity Sensitive Organic Field Effect Transistor, J. Semicond., 2010, 31, 054001.

10. Bukhari, S. B.; Memon, S.; Mahroof-Tahir, M.; Bhanger, M. I., “Synthesis, Characterization and Antioxidant Activity of Copper-quercetin Complex,” Spectrochimi. Acta - Part A: Mol. and Biomol. Spec., 2009, 71, 1901-1906. 11. Shah, M.; Sayyad, M. H., Karimov, K. S., Maroof-Tahir, M., “Fabrication and electrical characterization of the surface-type Au/NiPc/Ag diode”, J. Optoelectron. Adv. Mat. --Rapid Communications, 2009, 3, 831-834. 12. Mahroof-Tahir, M.; Karimov, K. S., “Fabrication of heterojunctions and current-voltage characteristics of vanadium coordination compounds,” J. Optoelectron. Adv. Mat., 2009, 11, 83 – 88. 13. Ashiq, U.; Ara, R.; Mahroof-Tahir, M.; Maqsood, Z. T.; Khan, K. M.; Omer, I.; Choudhary, M. I., “Studies of Enzyme Inhibition, Radical Scavanging and Spectroscopic Studies of Vanadium(IV)Hydrazide Complexes,” J. Enz Inhibit Med Chem, 24 (6), 2009, 1336-1343. 14. Ashiq, U.; Jamal, R. A.; Mahroof-Tahir, M.; Keramidas, A. D.; Maqsood, Z. T.; Khan, K.; Tahir, M. N., “Crystal Structure of 4-Bromobenzohydrazide,” Anal. Chem., X-Ray Structure Analysis, 2008, 24, X103-X104. 15. Ashiq, U.; Ara, R.; Mahroof-Tahir, M.; Maqsood, Z. T.; Khan, K. M.; Khan, S. N.; Siddiqui, H.; Choudhary, M. I., “Synthesis, Spectroscopy, and Biological Properties of Vanadium(IV)-hydrazide Complexes,” Chemistry and Biodiversity, 2008, 5, 82-92. 16. Karimov, K.S.; Qazi, I.; Draper, P.H.; Khalid, F.A.; Mahroof-Tahir, M.; Khan, T.A., "Humidity and Illumination Organic Semiconductor Copper Phthalocyanine Sensor for Environmental Monitoring," Environ. Monit. and Assess., 2008, 141, 323-328. 17. Karimov, K.S.; Qazi, I.; Mahroof-Tahir, M.; Khan, T.A.; Shafique, U., " Photo Organic Field Effect Transistor's Properties," Turk. J. Phys., 2008, 32, 1-7. 18. Bukhari, B. S.; Memon, S.; Mahroof Tahir, M.; Bhanger, M. I., “Synthesis, Characterization and Investigation of Antioxidant Activity of Cobalt-quercetin Complex,” Journal of Molecular Structure, 2008, 892, 39-46. 19. Ara, R.; Ashiq, U.; Mahroof-Tahir, M.; Maqsood, Z. T.; Khan, K. M.; Lodhi, M. A.; Choudhary, M. I., “Chemistry, Urease Inhibition, and Phytotoxic Studies of Binuclear Vanadium (IV) Complexes,” Chemistry and Biodiversity, 2007, 4, 58-71. 20. Karimov, K. S.; Qazi, I.; Khan, T. A.; Draper, P. H.; Khalid, F. A.; Mahroof-Tahir, M., “Humidity and Illumination Organic Semiconductor Copper Phthalocyanine Sensor for Environmental Monitoring,” Environ Monit Assess, Springer Science and Business Media, B.V. 2007. 21. Willsky, G. R.; Godzalla, M. E. III; Kostyniak, P. J.; Chi, L-H.; Gupta, R.; Yuen, V. G.; McNeill, J. H.; Mahroof-Tahir, M.; Smee, J. J.; Yang, L.; Lobernick, A.; Watson, S.; Crans, D. C., “Comparing Administration Route in Rats with Streptozocin-induced Diabetes and Inhibition of Myoblast Growth of Vanadium [V(III), V(IV), and V(V)] Dipicolinic Acid Complexes,” ACS Symposium Series 2007, 974, 93-109. 22. Maqsood, Z. T.; Khan, K. M.;, Ashiq, U.; Jamal, R. A.; Chohan, Z. A.; Mahroof-Tahir, M.; Supuran, C. T., “Oxovanadium(IV) Complexes of Hydrazides: Potential Antifungal Agents,” J. Enz. Inhib. Med. Chem., 2006, 21, 37–42. 23. Mahroof-Tahir, M.; Brezina, D.; Fatima, N.; Choudhary, M. I.; Rahman, A. U., “Synthesis and Characterization of Mononuclear Vanadium(IV) Complexes and their Enzyme Inhibition Studies

with a Carbohydrate Metabolic Enzyme, Phosphodiesterase I,” J. Inorg. Biochem., 2005, 99, 589– 599. 24. Lampronti, I.; Bianchi, N.; Borgatti, M.; Fabbri, E.; Vizziello, L.; Khan, M. T. H.; Ather, A.; Brezena, D.; Mahroof-Tahir, M.; Gambari, R., “Effects of Vanadium Complexes on Cell Growth of Human Leukemia Cells and on Protein-DNA Interactions,” Oncology Report, 2005, 14, 9-15. 25. Crans, D. C.; Mahroof-Tahir, M.; Johnson, M. D.; Wilkins, P. C.; Yang, L.; Robbins, K.; Johnson, A.; Alfano, J. A.; Godzala, M. I. III, “Vanadium(IV) and Vanadium(V) Complexes of Dipicolinic Acid and Derivatives. Synthesis, X-ray Structure, Solution State Properties and Effects in Rats with STZ-induced Diabetes”, Inorg. Chim. Acta, 2003, 356C, 365-378. 26. Crans, D. C.; Yang, L.; Alfano, J. A.; Chi, L-H.; Jin, W.; Mahroof-Tahir, M.; Robbins, K.; Toloue, M. M.; Chan, L. K.; Plante, A. J.; Grayson, R. Z.; Willsky, G. R., “(4-Hydroxypyridine-2,6dicarboxylato)oxovanadate(V)-A New Insulin-Like Compound: Chemistry, Effects on Myoblast and Yeast Cell Growth and Effects on Hyperglycemia in Rats with STZ-Induced Diabetes”, Coord. Chem. Rev., 2003, 237, 13-22. 27. Karimov, K. S.; Akhmedov, K. M.; Marupov, R.; Mahroof-Tahir, M.; Gul, R. M.; Valiev, J.; Homidov, I., “Dependence of Compensative Effect on Temperature in New c Rbazolile Contained Polymeric Complexes”, Proceed. Acad. Sc. Repub. Tajikistan, 2001, 9-10, 4-8. 28. Karimov, K. S.; Akhmedov, K. M.; Marupov, R.; Valiev, J.; Homidov, I.; Turaeva, M. A.; Mahroof-Tahir, M.; Gul, R. M., “Structure and Electric Properties of Poly-N-Epoxipropylcarbazole and Copper Phthalocyanine Films Deposited from Solution at High Gravity,” Proceed. Acad. Sc. Repub. Tajikistan, 2001, 9-10, 73-79. 29. Karimov, K.; Akhmedov, K.; Mahroof-Tahir, M.; Gul, R. M.; and Ashurov, A., “Influence of Centrifugation on the Conductivity of Poly-N-Epoxypropylcarbazole - Copper Phthalocyanine Films Deposited from Solution”, in Processing by Centrifugation (proceedings) edited by L. L. Regel and W.R. Wilcox, Kluwer Academic Publishers, 2001, pp 93-98. 30. Murthy, N. N.; Mahroof-Tahir, M. M.; and Karlin, K. D., “Dicopper(I) Complexes of Unsymmetrical Binucleating Ligands and Their Dioxygen Reactivities,” Inorg. Chem., 2001, 40, 628-635. 31. Crans, D. C.; Khan, A. R.; Mahroof-Tahir, M,; Mondal, S.; Miller, S. M.; la Cour, A.; Anderson, O. P.; Jakusch, T.; Kiss, T., “Bis(acetylamido)oxovanadium(IV) Complexes: Solid State and Solution Studies,” J. Chem. Soc., Dalton Trans., 2001, 3337-3345. 32. Jiang, F.; Anderson, O. P.; Miller, M.; Chen, J.; Mahroof-Tahir, M.; Crans, D. C., “Stepwise Cluster Assembly Using VO2(acac) as a presursor: cis-[VO(OCH(CH3)2(acac)2], [V2O2(OCH3)2(acac)2(OCH3)2], V3O3-OCH3)2CCH3}2(acac)2(OC2H5), V4O4)2 (OCH3)2(3-OCH3)2(acac)2(OCH3)2].2CH3CN,” Inorg. Chem., 1998, 37, 5439-5451. 33. Root, D. E.; Mahroof-Tahir, M.; Karlin, K. D.; Solomon, E. I., "The Effect of Protonation on Peroxo-Copper Bonding: Spectroscopic and Electronic Sturcture Study of [Cu 2(UN-O-)(OOH)]2+,” Inorg. Chem., 1998, 37, 4838–4848. 34. Plusky, S.; Mahroof-Tahir, M.; Crans, D. C.; Lawrence, D. S., "Vanadium Oxoanions and cAMP Dependent Protein Kinase: An antisubstrate Inhibitor,” Biochem. J., 1997, 321, 333-339. 35. Mahroof-Tahir, M.; Crans, D. C.; Anderson, O. P.; Miller, M., "Solution and Solid State Properties of [N-(2-Hydroxylethyl)iminodiacetato]vanadium(IV),V and IV/V Complexes”, Inorg. Chem. 1997, 36, 1657-1668.

36. Crans, D. C.; Mahroof-Tahir, M.; Keramidas, A. D.; Anderson, O. P.; Miller, M., “Factors Affecting Solution Properties of Vanadium(V) Compounds: X-Ray Structure of -cis NH4[VO2(EDDA)],” Inorg. Chem. 1996, 35, 3599-3606. 37. Crans, D. C.; Mahroof-Tahir, M.; Keramidas, A. D., "Vanadium Chemistry and Biochemistry of Relevance for Use of Vanadium Compounds as Antidiabetic Agents," Molecul. Cell. Biochem., 1995, 153, 17-24. 38. Ray, W. J., Jr.; Crans, D. C.; Zheng, J.; Burgner, J. W., II; Deng, H.; Mahroof-Tahir, M., "Structure of the Dimeric Ethylene Glycol-Vanadate Complex and Other 1,2-Diol-Vanadate Complexes in Aqueous Solution: Vanadate-Based Transition State Analog Complexes of Phosphotransferases," J. Am. Chem. Soc. 1995, 117 (22), 6015-26. 39. Crans, D. C.; Mahroof-Tahir, M.; Anderson, O. P.; Miller, M. M. "X-Ray Structure of (NH4)6(GlyGly)2V10O28.4H2O: Model Studies for Polyoxometalate-Protein Interactions," Inorg. Chem. 1994, 33, 5586-5590. 40. Mahroof-Tahir, M.; Karlin, K. D.; Chin, Q.; Zubieta. J. "Phosphate Ester Coordination to Dicopper(II) Compounds: X-Ray Structure of a Bis(4-Nitrophenyl)phosphato Bridged Dicopper(II) Complex," Inorg. Chim. Acta., 1993, 207, 135-138. 41. Murthy, N. N.; Mahroof-Tahir, M.; Karlin, K. D., "Facile Amide Hydrolysis Effected by Dinuclear Copper Complexes," J. Am. Chem. Soc., 1993, 115, 10404-10405. 42. Mahroof-Tahir, M.; Murthy, N. N.; Karlin, K. D.; Blackburn, N. J.; Shaikh, S. N. Zubieta, J., "New Thermally Stable Hydroperoxo and Peroxo Dicopper(II) Complexes," Inorg. Chem. 1992, 31, 3001-3003. 43. Mahroof-Tahir, M.; Karlin, K. D., "A Dinuclear Mixed Valence Cu(I)/Cu(II) Complex and Its Reversible Reaction with Dioxygen: Generation of a Superoxodicopper(II) Species," J. Am. Chem. Soc. 1992, 114, 7599-7601. 44. Sanyal I.; Mahroof-Tahir, M.; Nasir, M. S.; Ghosh, P.; Cohen, B. I.; Gultneh, Y.; Cruse, R. W.; Farooq, A.; Karlin, K. D.; Liu, S.; Zubieta, J., "Reactions of Dioxygen (O2) with Mononuclear Cu(I) Complexes: Temperature Dependent Formation of Peroxo- or Oxo- (and Dihydroxo) Bridged Dicopper(II) Complexes", Inorg. Chem., 1992, 31, 4322-4332.

Presentations in National and International Conferences: 1. Mahroof-Tahir M.; Willing, A. N., Girmay, S. K., “Solid and Solution State Chemistry of Potential Anticancer Titanium-Flavonoid Complexes,” Gordon Research Conference, Metals in Medicine, Proctor Academy, NH, USA, June 27 – July 02, 2010.

2. Karimov, K. S.; Fauzi, A.; Yew, C. K.; Mahroof-Tahir, M.; Qazi, I.; Murtaza, I.; Karieva, Z. M., “Organic-on-Inorganic Ag/VOPc/n-Si/Ag Photocapacitive Sensor,” 4th International Conference on Recent Advances in Materials, Minerals & Environment and 2nd Asian Symposium on Materials & Processing, Ramm & Asmp '09, Excellence in Materials, Minerals, and Environmental Research for Sustainable Tomorrow, 1 – 3 June 2009. 3. Yaseen, M.; Ali, M.; Karimov, K. S.; Qazi, I.; Mahroof-Tahir, M.; Murtaza, I.; Amin, T.; Abbas, S.Z., "Opto-electronic properties of ITO/CuPc/NiPc/Al and ITO/NiPc/CuPc/Al double junction cells," Proc. 6th International Conference on Electrical Engineering (ICEENG 2008) Conference, Cairo, Egypt, 27-29 May, 2008, pp.1014-1027.

4. Khan, T. A.; Karimov, K. S.; Qazi, I.; Tahir, M. M.; Moiz, S. A.; Murtaza, I.; Karieva, Z. M.; Shafique, U., "Electrical Properties of Organic Semiconductor Copper Phthalocyanine-Metal Junction," Proc.10th International Symposium on Advanced Materials, 2007, pp.311-319. 5. Khan, T. A.; Karimov, K. S.; Qazi; I.; Mahroof-Tahir, M.; Moiz, S. A.; Karimov; K.; Qazi, I.; Shafique, U.; Mahroof-Tahir, M.; Khan, T.; Zaidi, N. H., “Copper Phthalocyanine based Organic Photo Field Effect Transistor as a sensor for optical instrumentation,” IEEE International Conference on Signal Processing and Communication, 24-27 November, 2007, Dubai, United Arab Emirates. 6. Khan, T. A.; Karimov, K. S.; Qazi, I.; Mahroof-Tahir, M.; Moiz, S. A.; Murtaza, I.; Shafique, U. , "Elecrical Properties of Organic Semiconductor Copper Phthalocyanine-Metal Schottky Type Junction," China NANO 2007, International Conference on Nanoscience and Technology, China 2007, June 4-6, 2007, Beijing, China, pp.428-429. 7. Legatt, G. A.; Fernando, K. G.; Mahroof-Tahir, M.; Sreerama, L., “Induction/activation of phosphotidyl inositol 3-kinase by vanadium-flavonoid complexes,” 233rd American Chemical Society National Meeting, March 25-29, 2007, Chicago, IL, USA. 8. Mahroof-Tahir, M.;D. Gregory, D., Bushkofsky, J. R.; Swingley, L. E.; Eannelli, M. A., “Synthesis and characterization of vanadium flavonoid complexes in solid and solution states”, Abstract #INOR 918, 5th International Vanadium Symposium the Fifth International Symposium on the Chemistry and Biological Chemistry of Vanadium, ACS National Meeting, September 10-14, 2006, San Francisco, California, USA. 9. Bushkofsky, J.; Mahroof-Tahir, M.,, “Chemistry of Vanadium-Flavonoid Complexes: Potential Antidiabetic Properties”, 231st American Chemical Society National Meeting, Atlanta, GA, March 2630, 2006. 10. Swingley, L., Mahroof-Tahir, M., Synthesis and Characterizationof Vanadium-3-hydroxyflavone Coordinated Compounds: Role as Potential Antidibetic Agents, Research Curriculum, St. Cloud State University, Spring 2006. 11. Piere, C.; Mahroof-Tahir, M.; Gazal, O., Solution Speciation and Anti-Diabetic Properties of VO(pbd)2 and VO(dbm)2, Research Curriculum, St. Cloud State University, Spring 2005 12. Jordan C. V.; Mahroof-Tahir, M.; “Hydrothermal Synthesis and Characterization of Novel Vanadium-Flavonoid Complexes with potential Insulin-Mimetic and Anticancer properties,” Research Curriculum, St. Cloud State University, Spring 2005. 13. Bushkofsky, J.; Mahroof-Tahir, M., “Synthesis and Characterization of Vanadium Flavonoid Coordination Compounds,” Research Curriculum, St. Cloud State University, Spring 2005. 14. Luke Roskop, Mahroof-Tahir, M.; Gregory, D., “Characterization of Vanadium-oxo Compounds Using Computational Chemistry,” Research Curriculum, St. Cloud State University, Spring 2005. 15. Sreerama, R.; Mahroof-Tahir, M., “Interdisciplinary Research Experience: Opening Avenues to Meaningful Science Learning for Undergraduates”, Crossing Boundaries: Innovations in Undergraduate Research, Council on Undergraduate Research, Tenth National Conference, University of Wisconsin – La Crosse, June 23-26, 2004. 16. Mills, T.; Mahroof-Tahir, M.; Sreerama, R.; Schuh, T., “Synthesis, Characterization, Toxic Effects, and Anti-Cancer, Properties of a New Vanadium Metal Complex: VO(DBM) 2,” Research Curriculum, St. Cloud State University, Spring 2004. 17. Sitzman, A.; Mahroof-Tahir, M.; Sreerama, R., “Spectroscopic Characterization of Vanadium Complex VO(PBD)2: Toxicity Effects and Anticancer Properties,” Research Curriculum, St. Cloud State University, Spring 2004.

18. Cleland, M.; Nguyen, A.; Mahroof-Tahir, M.; Sreerama, R., “Synthesis, Characterization and Anticancer Activity of Ti and Ruthenium Complexes,” Research Curriculum, St. Cloud State University, Spring 2004. 19. Brezina, D.; Mahroof-Tahir, M.; Sreerama, R., “Synthesis, Characterization and Antitumour Properties of Ru-, Ti-, and V- Complexes with EDTA like Ligands,” Research Curriculum, St. Cloud State University, Spring 2004. 20. Otremba, J.; Mahroof-Tahir, M.; Sreerama, R., Anticancer Activity of 3-Ti-(OiPr)2, Curriculum, St. Cloud State University, Spring 2004.

Research

21. Cleland, M.; Mills, T.; Mahroof-Tahir, M., “Synthesis and Characterization of Vanadium Complexes with Bidentate Ligand: Potential Antidiabetic Properties,” Research Curriculum, St. Cloud State University, Spring 2003. 22. Otremba, J.; Sitzman, A.; Mahroof-Tahir, M., “Synthesis and Spectroscopic Studies of Vanadium Complexes with Insulin Like Properties,” Research Curriculum, St. Cloud State University, Spring 2003. 23. Mahroof-Tahir, M.; Anderson, A., “Structural Investigation of Vanadium Tetracycline and Anhydrotetracycline Adducts,” National Meeting of American Chemical Society, New Orleans, Louisiana, March, 23-27, 2003. 24. Mahroof-Tahir, M.; Dovalle, D., “Synthesis, characterization and spectroscopic studies of vanadium(IV) complexes with beta-diketonate ligands: potentials chemical and biochemical catalysts “, National meeting of American Chemical Society held in New Orleans, Louisiana, March, 23-27, 2003. 25. Bailey, C. T.; Mahroof-Tahir, M., “The Inside Box Conference”, Case Studies Workshop in University of Buffalo, New York, May 20-24, 2002. 26. Mahroof-Tahir, M.; Johnson, A.; Alfano, J. A.; Willsky, G. R.; Crans, D. C., “Synthesis, Characterization and Insulin-Like Properties of Mononuclear Vanadium (V/IV) Complexes of the Derivatives of Dipicolinic Acid Ligand,” 34th Grate Lakes Regional Meeting of American Chemical Society, Minneapolis, MN, June 2-4, 2002. 27. Mahroof-Tahir, M.; Anderson, A., “Structural Investigation of Vanadium Tetracycline and Anhydrotetracycline Adducts”, National Meeting of American Chemical Society, Orlado, Florida, April, 7-11, 2002. 28. Mahroof-Tahir, M, “Case Studies in Chemistry: Development of Analytical and Critical Thinking Skills”, Teaching Learning Methods in General Chemistry, St. Cloud State University, October 2526, 2002. 29. Scanlan, M.; Mahroof-Tahir, M.; Sreerama, L., “Inhibition/Activation of Human ALDH1a1 by Vanadium Complexes,” Research Curriculum, St. Cloud State University, Spring 2002. 30. Dechaine, J.; Mahroof-Tahir, M.; Sreerama, L., “The Effects of Vanadium Complexes on Class-2 Aldehyde Dehydrogenase,” Research Curriculum, St. Cloud State University, Spring 2002. 31. Mahroof-Tahir, M.; Crans, D. C.; Khan, A. R.; Mondal, S.; .; Anderson, O. P.; Miller, S. M.; Cour, A.; Jakusch, T and Kiss, K., “Solid and Solution State Characterization of bis(acetylamido) oxovanadium(IV) Complexes,” 219th American Chemical Society National Meeting, SF California, March, 26-30, 2000. 32. Karimov, K.; and Akhmedov, K.; Mahroof-Tahir, M.; Gul, R. M., “Influence of Centrifugation on the Conductivity of Poly-N-Epoxypropylcarbazole-Copper Phthalocyanine Films Deposited from Solution”, Centrifugal Materials Processing IV The Fourth International Workshop on Materials

Processing at High Gravity, May 29 to June 2, 2000; Clarkson University, Potsdam, New York 13699-5814. 33. Cryer, K.; Mahroof-Tahir, M; Amin, S. S.; Zhang, B.; Mondal. S. K.; Khan, A. R.; Yang, L.; Anderson, O. P.; Miller, S. M.; Crans, D. C., “Solid state and aqueous solution chemistry of parent and heteroatom,-containing symmetric and asymmetric bis(acetylacetonate) oxovanadium(IV) derivatives,” 41st Rocky Mountain Conference on Anal. Chem., Denver, Colorado, August 1-5, 1999. 34. Gul, R. M.; Mahroof-Tahir, M.; Karimov, K. S., Akhmedov, K. M., “Relationship of Electro-physical Properties, Thermal Phase Transition and Microstructure of Organic Semiconductor Crystals,” Proceedings of the 6th International Symposium on Advanced Materials, Islamabad , Pakistan, 1999, pp.81-83. 35. Etcheverry, S. B.; Crans, D. C.; Mahroof Tahir, M.; Cortizo, A. M., "Determination of Vanadium Biologically Active Species in Cellular Cultures,” X Argentinean Physycochemical Congress, San Miguel de Tucuman, Argentina, April 21-25, 1997. 36. Mahroof-Tahir, M; Karlin, K. D. " Synthesis and Characterisation of Phenoxo Bridged Superoxo, Peroxo, Hydroperoxo and Acylperoxo Dicopper (II) Complexes," 6th All Pakistan Science Conference, NWFP Agriculture University, Peshawer, NWFP, Pakistan, November 3-6, 1997, P-10. 37. Crans, D. C.; Mahroof-Tahir, M.; Cartizo, A.; Etcheverry, S. B. "Insulin Mimetic Activity of Vanadium Compounds: In Vitro Study of the Active Site Species of Vanadium in Osteoblast Cell" Inorganic Biochemistry Summer Workshop, University of Georgia, Athens, July 30 - August 10, 1994. 38. Crans, D. C.; Mahroof-Tahir, M.; Shin, P. K.; Marshal, K. "Vanadium Chemistry of Relevance for Use of Vanadium Compounds as Diabetic Agents" Vanadium Symposium 1994, Vanadium : Biochemistry, Physiology and Potential Use in Diabetes Therapy, Montreal, Canada, July 30 - 31, 1994. 39. Crans, D. C.; Anastasios Keramidas,; Mahroof-Tahir, M., "Exploration of Aqueous Coordination Chemistry of Vanadium of Relevance to Biological Systems: Ethylenediamine Diacetic Acid and N(2-Hydroxyethyl) Iminodiacetic Acid Complexes", 208th American Chemical Society National Meeting, April, 1994. 40. Crans, D. C.; Cartizo, A. M.; Etcheverry, S. B, Mahroof-Tahir, M.; "In Vitro Insulin-Mimetic Activity of a Series of Vanadium Compounds: What are the Active Species", Vanadium Symposium 1994, Montreal, Canada, July 30 - 31, 1994. 41. Cortizo, A. M., Crans, D. C.; Mahroof-Tahir, M., Etcheverry, S. B., "Metabolism and insulin-mimetic effects of vanadium in cells in culture," IX Argentinian Congress of Diabetes, San Martin de Los Andes, Argentina, September 17-21, 1994. 42. Karlin, K. D.; Murthy, N. N.; Mahroof-Tahir, M.; Gan, Q. F., "Functional Models for Copper Proteins: Oxygenation and Hydrolysis Reactions Mediated by Reactions of O2 with Dicopper Complexes" American Chemical Society National Meeting, Denver, CO, March 28 - April 1, 1993, Abstract # 449. 43. Murthy, N. N.; Mahroof-Tahir, M.; Karlin, K. D. "Amide Hydrolysis Mediated by a Dinuclear Copper Complex with Terminal Cu-OH Ligation", Journal of Inorganic Biochemistry, 1993, 51, 506. 44. Crans, D. C.; Stites, S.; Mahroof-Tahir, M., "Interactions of Oxoanions with Glucose-6-Phosphate Dehydrogenase," ACS National Meeting, Denver, CO, March 28 - April 1, 1993, Abstract # 466.

45. Mahroof-Tahir, M.; Crans, D. C.; Anderson, O. P.; Miller, M. M., "X-Ray Structure of (NH4)6(GlyGly)2V10O28.4H2O as a Model for the Interaction of Polyoxovanadate with proteins", American Chemical Society Northwest Regional Meeting, Laramie, Wyoming, June 17-19, 1993, Abstract # 08. 46. Murthy, N. N.; Mahroof-Tahir, M.; Karlin, K. D., "Dioxygen Reactivity of a new Dinuclear Cu(I) Complex", Copper 92 Symposium on Copper Coordination Chemistry: Bioinorganic Perspectives Conference, The Johns Hopkins University, Baltimore, MD, August 4-7, 1992, Abstract #P24. 47. Murthy, N. N.; Mahroof-Tahir, M.; Karlin, K. D., "Dioxygen Reactivity of a New Dinuclear Cu(I) Complex", ACS 204th National Meeting, Washington, DC, August 23-28, 1992, INOR 434. 48. Mahroof-Tahir, M.; Karlin, K. D. "Reaction of Dioxygen with a Mixed Valence Copper(I)-Copper(II) Dinuclear Complex", Journal of Inorganic Biochemistry 1992, 47, 52. 49. Mahroof-Tahir, M.; Karlin, K. D., "Room Temperature Stable Copper-Dioxygen Complexes", 25th Middle Atlantic Regional Meeting (MARM), Newark, DE, May 21-23, 1991, Abstract #INOR 119. 50. Mahroof-Tahir, M.; Karlin, K. D., "New Copper-Dioxygen Complexes with Thermal Stability", 4th Chemical Congress of North America, New York, NY, August 25-30, 1991, Abstract # INOR 46.

Invited Lectures/Seminars: 1. Qatar University, Doha, Qatar – Medicinal Chemistry of Metals: Synthesis, Antioxidant and Antidiabetic Studies of Vanadium-Flavonoid Complexes – October 26, 2011 2. Quaid-i-Azam University, Islamabad, Pakistan -- Chemistry of Potential Antidiabetic Vanadium Complexes Solid and Solution State Studies – January 06, 2010 3. Quaid-i-Azam University, Islamabad, Pakistan -- Synthesis, Characterization and DNA Interaction Studies of Metal Complexes Using Atomic Force Microscopy to Explore Potential Anti-Cancer Properties – December 30, 2009 4. Department of Chemistry, Federal Urdu University, Karachi -- June 05, 2006. a. Chemistry of Vanadium Complexes with Falvonoids (Natural Products) Potential Antidiabetic Complexes. b. Brief Introduction of Education and Postdoctoral Positions in USA. 5. Department of Chemistry, University of Karachi – June 06, 2006. a. Mononuclear and Binuclear Copper Complexes: Synthetic Models of Copper Proteins. b. Brief Introduction of Education and Postdoctoral Positions in USA. 6. Center of Excellence in Analytical Chemistry, Sindh University, Jamshoro -- June 07, 2006 Solid and Solution State Chemistry of Potential Antidiabetic Vanadium-Flavonoid Complexes: Use of Modern Instrumental Techniques. 7. Department of Chemistry, University of Peshawar ---- May 26, 2006 Chemistry of Potential Antidiabetic Vanadium Complexes: Solid and Solution State Studies – 8. Center of Excellence in Physical Chemistry, University of Peshawar – May 30, 2006Synthetic Models of Copper Proteins: Dioxygen Chemistry of Mononuclear and Dinuclear Copper Complexes 9. Federal Urdu University: May 19, 2005:

Chemistry of Vanadium(IV) Complexes: Potential Antidiabetic Properties. 10. Jinnah Women University: May 21, 2005: Vanadium Complexes of Medicinal Importance: Synthesis and Characterization 11. Department of Pharmacy, University of Karachi: May 23, 2005: Metals and Medicine: Synthesis and Solution Speciation Studies of Potential Antidiabetic Anticancer Complexes of Vanadium.

and

12. Department of Biochemistry, University of Karachi: May 25, 2005: Solution characterization and Enzyme Inhibition Studies of Insulin Mimetic Vanadium Complexes 13. Golden Jubilee Lecture Series, University of Karachi: May 28, 2005: Synthesis, X-Ray Crystallography and Spectroscopic Characterization of Potential Antidiabetic Vanadium Complexes. 14. University of Sindh, Jamshoro: May 30, 2005: Synthesis of Antidiabetic Vanadium Complexes and their Characterization by using Advanced Instrumental Techniques. 15. University of Kharipur, Sindh: May 31, 2005: Synthesis, Solid and Solution State Characterization of Vanadium Complexes: Potential Antidiabetic and Anticancer Properties. 16. Baluchistan University of Information Technology and Management Sciences: a. What is Bioinorganic Chemistry? Role of Transition Metals in Some Key Biological Processes: July 07, 2005 b. Experimental Methods in the Study of Bioinorganic Systems: July 08, 2005 c. Diabetes, Insulin and Insulin Mimicking Compounds: July 08, 2005 d. Chemistry of Vanadium Complexes and Biochemical Relevance to their Insulin Mimicking Capabilities: July 08, 2005 e. Mono and Dicopper Complexes as Models of Copper Containing Proteins: July 09, 2005 f. New Avenues for Research in Biological Inorganic Chemistry and Possibilities of Collaboration Between the Universities of Baluchistan and the St. Cloud State University. 17. Department of Chemistry, University of Karachi, Pakistan, June 2003 Synthesis and Characterization of Potential Antidiabetic Oxovanadium Complexes. Participants included students and faculty members. 18. Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, Pakistan, June 2003 Synthesis and Characterization of Vanadium Complexes: Potential Antidiabetic Properties. Participants included students and faculty members. 19. Department of Biochemistry, Barani University, Islamabad, July, 2003 Vanadium and Diabetes: Synthesis and Characterization of Potential Antidiabetic Complexes of Vanadium. 20. St. Cloud State University, March 22, 2002 Searching for Metal-Based Chemotherapies; Research Collaboration Between St. Cloud State University and HEJ Research Institute, Pakistan Through United Nations Organization and Current Status of Platinum-Based Antitumor Drugs”.