Reagent Guide
Synthetic Organic Chemistry & Materials Chemistry
We have reviewed our line of reagents and organized them according to various fields such as synthetic organic chemistry, materials chemistry and their individual basic structures. We hope that this reagent guide will be of assistance to your research and development laboratories. However, this guide is not an all inclusive list of all the reagents we deal in. Please be sure to look up our catalog and visit our website as well to remain updated on the latest information in the various fields of your interest.
Contents Synthetic Organic Chemistry Environmentally-Friendly Oxidation .........................1 Ionic Liquids ................................................................5 Fluorous Chemistry ................................................. 13 Amphiphilic Polymer-assembled Pd Complex Catalyst .......................................... 21 Stable Lewis Acids in Aqueous Media ................ 22 Polymer-Supported Reagents ................................ 24 Asymmetric Organocatalysts ................................. 26 Asymmetric Synthesis............................................. 31 Chiral Building Blocks ............................................ 40 Optical Resolution ................................................... 60 Enantiomer Excess & Absolute Configuration Determination ....................................................... 67 Chiral Columns for HPLC....................................... 74 Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds ................ 76 Halogenation ............................................................ 85 New Oxidation of Primary & Secondary Alcohols ..... 90 Oxidation ................................................................... 93 Reduction .................................................................. 99 Mitsunobu Reaction ..............................................105 Condensation & Active Esterification .................108 Glycosylation ..........................................................113 Phosphorylation .....................................................123 Amination ................................................................124 Wittig & Horner-Emmons Reaction .....................126 Titanium-mediated Carbonyl Olefination ............131 Suzuki-Miyaura Cross-Coupling Reaction .........135 Iron-Catalyzed Organic Synthesis .......................141 Metal Catalysts for Organic Synthesis ...............144 Grignard Reagents & Alkyl Metals ......................151 Protection & Derivatization ..................................155 Silicon Compounds for Organic Synthesis ........162 Sulfur Compounds for Organic Synthesis ..........169 Phosphines for Organic Synthesis ......................178 Hypervalent Iodine Compounds ..........................182 Phase-Transfer Catalysts .....................................185 Combinatorial Chemistry ......................................188 Gas Cylinders .........................................................191 Precursors for Preparation of Highly Reactive Reagents ................................193
Materials Chemistry C60 & C70 The Third Form of Carbon ................196 Carbon Nanotube ..................................................197 Building Blocks for Dendrimers ...........................199 Organic Semiconducting Materials .....................202 Charge Transfer Complexes for Organic Metals ...205 Reagents for Conducting Polymer Research ....210 Electroluminescence .............................................218 Reagents for Solar Cell Research ......................240 Photochromic Compounds ...................................247 Liquid Crystals & Related Compounds ..............250 Building Blocks for Liquid Crystals .....................257 Organic Nonlinear Optical Materials ..................269 Phthalonitriles & Naphthalonitriles .....................271
Macrocycles for Host-Guest Chemistry .............275 Diacetylene Monocarboxylic Acids for LB Films ...281 Reagents for High-Performance Polymer Research ...282 Metal-Organic Frameworks (MOFs / PCPs) .....299 Photopolymerization Initiators..............................302 Silane Coupling Agents ........................................305 Pressure & Heat Sensitive Recording Materials ...310
Chemicals by Class Ethylene Glycols & Monofunctional Ethylene Glycols................315 Monoprotected Diaminoalkanes ..........................317 3-Aminopyrrolidines ...............................................318 -Substituted Maleimides, Succinimides & Phthalimides ...................................................321 1,4-Disubstituted Cyclohexanes .........................327 Monofunctional & α,ω-Bifunctional Alkanes ......333 ω-Functional Alkanols, Carboxylic Acids, Amines & Halides ..............................................334 Quaternary Ammonium Compounds ...................337 Imidazolium Compounds.......................................342 Pyridinium Compounds .........................................345 Phosphonium Compounds....................................350 Iodonium, Sulfonium & Oxonium Compounds ...354 Classes of Boron Compounds .............................357 Metallocenes ..........................................................374 Classes of Metal Compounds..............................378 Non-benzenoid Aromatic Compounds ................394 NMR Spectrometry ................................................396 Standards for Mass Spectrometry & Matrix Materials .............................................398 TLC Stains ..............................................................400 Abbreviations ..........................................................402 Pressure-Temperature Nomograph .....................403 The physical properties of the typical organic solvents / Freezing mixtures............................404 Periodic Table of the Elements ...........................405 TCI International Offices .......................................406 TCI Distributors ......................................................407 If you are looking for products in the field of Bioscience & Analytical Science, please see below.
Reagent Guide Bioscience & Analytical Science Bioscience Example : Antibody / Sugars / Nucleosides / Amino Acids / Lipids and Related Compounds / Terpenes / Steroids etc. Analytical Science Example : Reagent for Protein Analysis DAABD-Cl / GC Derivatizing Reagents / Labeling Reagents for HPLC / Chromatography Columns for HPLC etc.
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Environmentally-Friendly Oxidation
Environmentally-Friendly Oxidation In recent years, organic synthesis has improved to the point of being environmentally-friendly. Many excellent methodologies have been devised for green chemistry and environmentally-friendly manufacturing. Oxidation reactions employing atmospheric oxygen or molecular oxygen as an oxidant is one of the methodologies of green chemistry. The earth is filled with air, and about 20% of air is oxygen. If oxygen could be utilized as the oxidant, this would provide a method that is not only economically prudent, but also environmentally clean. However, the oxidation capability of atmospheric oxygen and molecular oxygen is not powerful enough when used alone. Therefore, there is much active R&D underway to make improvements in the oxidation capability with the presence of transition metal complex catalysts and radical producing catalysts.1) For example, Markó and co-workers have reported that tetrapropylammonium perruthenate (TPAP) can be used for the oxidation of alcohols to aldehydes and ketones using molecular oxygen as the oxidant.2) Similarly, Uemura and co-workers have demonstrated that palladium(II) diacetate is also a catalyst for the same type of oxidations.3) Katsuki and co-workers reported the oxidation method of alcohols using (nitrosyl) Ru-Salen complex as a catalyst.4) This catalyst is activated by photo-irradiation and can be used to oxidize primary alcohols to aldehydes selectively. Fukuzumi and co-workers reported the oxygenation using 9-aromatic substituted acridinium derivatives as effective electron-transfer photocatalysts.5) Ishii and his group have reported a catalytic carbon radical formation method using -hydroxyphthalimide (NHPI).6) In this method, the hydrogen atom of the hydroxyimino group in NHPI is pulled off by molecular oxygen, thereby producing a phthalimide -oxyl (PINO) radical. The PINO radical then pulls hydrogen atoms from carbon-hydrogen bonds such as alkanes and alcohols to furnish the corresponding carbon radicals. The resulting carbon radicals readily react with different types of molecules, thereby producing oxygen-containing compounds such as carboxylic acids under an oxygen atmosphere. A porous metal-organic framework (MOF) (porous coordination polymers (PCP)) pre-ELM-11 is also utilized as a catalyst in organic synthesis for molecular oxygen-derived oxidation.7) Typical transition metal complex catalysts and carbon radical producing catalysts for oxidation using molecular oxygen are as follows.
C0373
B2681 CH3
CH3 Co
T0746
O
O
Co
V O O
O CH3
. xH2O
2
S0318
CH3
O Co
Mn
O CH3
2
C1944
CF3
CH3
. 2H2O
O CH3
V0016
CH3 O
O
Transition Metal Complexes
M0042
O CH3
2
A1424
H3C CH3 H3C CH3 N NO N Ru O C(CH3)3 (CH3)3C O Cl C(CH3)3 (CH3)3C
2
P1870
O
O CH3 C O
Pd2
CF3
2
O
Pd2 2
2
T1559
I0079
D1997 CH3
N
Pr
Co O
Pr
N O
N Pr
O RuO4 CH3
Product No. Product Name C0373 B2681 M0042 V0016
P
Fe 3
O
Pr
Bis(2,4-pentanedionato)cobalt(II) Dihydrate Bis(2,4-pentanedionato)cobalt(II) Bis(2,4-pentanedionato)manganese(II) Dihydrate Bis(2,4-pentanedionato)vanadium(IV) Oxide
Rh
Cl Cl
3
3
Unit Size 25g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500g 25g 500g 25g
1
Environmentally-Friendly Oxidation
Product No. Product Name T0746 C1944
Unit Size
Bis(trifluoro-2,4-pentanedionato)cobalt(II) Hydrate Chloronitrosyl[N,N '-bis(3,5-di-tert-butylsalicylidene)-1,1,2,2-tetramethylethylenediaminato]ruthenium(IV) Palladium(II) Acetate Palladium(II) Trifluoroacetate Salcomine Tetrapropylammonium Perruthenate Tris(2,4-pentanedionato)iron(III) Tris(triphenylphosphine)ruthenium(II) Dichloride
A1424 P1870 S0318 T1559 I0079 D1997
B2897
5g
25g
D3428
1g 1g 100g 1g 25g 1g
100mg 5g 5g 500g 5g 500g 5g
D3429
CH3
CH3
CH3
CH3
Radical Producing Catalysts N
N ClO4
CH3
H1036
H0395
M1774
CH3
M2072
O
N OH
ClO4 CH3
CH3
CH3
CH3
CH3
O
N CH3
CH3
N
N CH3
ClO4
CH3
Product No. Product Name B2897 D3428 D3429 H1036 H0395 M1774 M2072 M1775
ClO4
M1775
O
O2N N OH
CH3
CH3
CH3
O
N
ClO4
ClO4
Unit Size
9-(2-Biphenylyl)-10-methylacridinium Perchlorate 9-(2,5-Dimethylphenyl)-10-methylacridinium Perchlorate 9-(2,6-Dimethylphenyl)-10-methylacridinium Perchlorate N-Hydroxy-4-nitrophthalimide N-Hydroxyphthalimide 9-Mesityl-10-methylacridinium Perchlorate 9-Mesityl-2,7,10-trimethylacridinium Perchlorate 10-Methyl-9-phenylacridinium Perchlorate
H0186
1g 1g 1g 25g 1g 1g
5g 5g 5g 5g 500g 5g 1g 5g
T1560 OH CH3
Redox Catalysts
CH3 OH
Product No. Product Name H0186 T1560
2
Hydroquinone 2,2,6,6-Tetramethylpiperidine 1-Oxyl Free Radical
CH3 N
CH3
O
Unit Size 25g 5g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
500g 25g
Environmentally-Friendly Oxidation
P0052
A0869
B0989 NaO3S
O
Ligands
CH3
B1733
D1678
O
O
C CH2
C
CH3
P1297
CH3
CH3
T1438 O
CH3
CH3
CH3
Cl
N
P0160 N
O
. H2O
O
CH3 C CH2 C
CH3
T0434
T0519
Cl
Cl
Cl NH N
N
NH N
HN
Cl
O
N HN
Cl Cl
N
N
CH3
T1359
O CH3
O
CH3
OCH3
. xH2O
O
P0221 P0879 O
O
CH3
C CH3
CH3
M1132 O
CH3O
SO3Na
O
O
O P
CF3
CH3
Cl
Product No. Product Name
Unit Size
P0052 A0869 B0989 B1733 D1678 M1132 P0221 P0879 P0160 P1297 T1438 T1359 T0434 T0519
25ml
Acetylacetone 2-Acetylcyclopentanone Bathophenanthrolinedisulfonic Acid Disodium Salt Hydrate [for Determination of Ferrous Ion] 1,3-Bis(4-methoxyphenyl)-1,3-propanedione Dipivaloylmethane 3-Methyl-2,4-pentanedione 1,10-Phenanthroline Monohydrate 1,10-Phenanthroline Monohydrate 1-Phenyl-1,3-butanedione 3-Phenyl-2,4-pentanedione 5,10,15,20-Tetrakis(2,6-dichlorophenyl)porphyrin Tetraphenylporphyrin (Chlorin free) Trifluoroacetylacetone Triphenylphosphine
1g 5g 5g 5ml 1g 25g 1g
25g 25g
500ml 25ml 5g 25g 25g 25ml 25g 25g 500g 5g 100mg 1g 100g 500g
C2409
MOF / PCP
[Cu(bpy)(BF4)2(H2O)2]bpy
Product No. Product Name C2409
Unit Size
pre-ELM-11
5g
Metal-Organic Frameworks (MOFs/PCPs) (see p.299)
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
3
Environmentally-Friendly Oxidation
References 1) Review: C. N. Cornell, M. S. Sigman, in , ed. by W. B. Tolman, Wiley-VCH, Weinheim, 2006, pp.159-186; T. Punniyamurthy, S. Velusamy, J. Iqbal, . 2005, , 2329; I. W. C. E. Arends, R. A. Sheldon, in , ed. by J.-E. Bäckwall, Wiley-VCH, Weinheim, 2004, pp.83-118. 2) I. E. Markó, P. R. Giles, M. Tsukazaki, I. Chellé-Regnaut, C. J. Urch, S. M. Brown, . 1997, , 12661. 3) T. Nishimura, T. Onoue, K. Ohe, S. Uemura, . 1998, , 6011. 2004, number 4) A. Miyata, M. Murakami, R. Irie, T. Katsuki, . 2001, , 7067; T. Katsuki, , 2. 5) S. Fukuzumi, H. Kotani, K. Ohkubo, N. V. Tkachenko, H. Lemmetyinen, . 2004, , 1600; H. Kotani, K. Ohkubo, S. Fukuzumi, . 2004, , 15999. 6) Y. Ishii, T. Iwahama, S. Sakaguchi, K. Nakayama, Y. Nishiyama, . 1996, , 4520; Y. Ishii, S. Sakaguchi, 2002, number 2001, , 2; Y. Ishii, , 2. 7) T. Arai, H. Takasugi, T. Sato, H. Noguchi, H. Kanoh, K. Kaneko, A. Yanagisawa, . 2005, , 1590; T. Arai, T. Sato, H. Noguchi, H. Kanoh, K. Kaneko, A. Yanagisawa, . 2006, , 1094; D. Jiang, T. Mallat, F. Krumeich, A. Baiker, . 2008, , 390.
4
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Ionic Liquids
Ionic Liquids Ionic liquids are salts composed of cations such as imidazolium ions, pyridinium ions and anions such as BF4‒, PF6‒ and are liquid at relatively low temperatures. Their characteristic properties include; (1) essentially no vapor pressure, (2) non-flammability, (3) high thermal stability, (4) relatively low viscosity, (5) liquid state over extended temperature ranges, (6) high ionic conductivity. Applications of ionic liquids with these features are being vigorously explored in various fields. When an ionic liquid is used as a reaction solvent, the solute is solvated by ions only. Thus, the reaction proceeds in an environment totally different from that when water or ordinary organic solvents are used and therefore, high selectivity is possible. To date application in the Friedel-Crafts reaction, the Diels-Alder reaction, metal-catalyzed asymmetric synthesis and so forth, have been reported.1) Furthermore, some ionic liquids have low solubility in water and low polar organic solvents. By using this property, ionic liquids can be recovered and reused after reaction product is extracted with organic solvents. Recently, methods are being studied which reduce the load on the environment from the viewpoint of green chemistry. Ionic liquids are receiving much attention as a superb solvent from the point of safety, separation/purification procedures, and recyclability.2) Ionic liquids are used not only as a reaction solvent but also electrochemically, for example, as electrolytes of rechargeable batteries.3) Watanabe and co-workers have developed a novel solid electrolyte in which an ionic liquid is confined in a network polymer called“ion gel”.4) This ion gel is expected to contribute to solidification of various electrochemical systems and safety improvement as it exhibits exceedingly high ion-conductivity compared with conventional solid polymer electrolytes. Hamaguchi and co-workers reported that 1-butyl-3-methylimidazolium tetrachloroferrate is magnetic ionic liquid.5) The new magnetic ionic liquid overcomes various problems of traditional magnetic fluids, and is expected to be applied to many fields including the use as a sealing agent for the motor axis. Below shows the major ionic liquids. The melting points are shown as the reference value. These are not specification value. The salts that form liquid state at room temperature are given the description“liquid” .
D3341
D3240 CH3
N
CH3 CH3O
Cl
N
Imidazolium & Pyrrolidinium Salts
N
E0490
N
CH3
CH3O
N
E0755
CH3 Br
N
I
N
CH2CH3
N
mp 74 ℃
N
CH3 HSO4
N CH2CH3
N
N
Liquid
N
N
(CF3SO2)2N
CH2CH3
N
BF4
N
N
mp 61 ℃ B2193
N N
CH3 Cl
(CH2)3CH3
Liquid
PF6
CH2CH3
Liquid
CH3 I
CH3
N
CH2CH3
CH2CH2CH3
Liquid
N
B2194
N
FeCl4
CH3
Liquid
CH3
CH2CH3
Liquid
N
M1440
CH3
N
N
(NC)2N
Liquid E0493
CH3
Liquid E0706
E0599
Liquid
CH2CH3
CH2CH3
CF3BF3
N CH2CH3
E0496
CH3 CH3CH2OSO3
CF3SO3
N
CH3
N
Liquid E0680
N
CH3
CH2CH3
mp 79 ℃ E0650
E0754
CH3SO3
mp 84 ℃ E0836
N
CH2CH3
CH2CH3
Liquid
CH3
N
Cl
N CH2CH3
E0494
CH3
N
P O
CH3
mp 125 ℃ E0556
E0543
CH3
N
O
N
CH3
N
Br
(CH2)3CH3
mp 41 ℃
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
Liquid
5
Ionic Liquids
B2708
B2337
B3542
CH3
N
N
CH3
N
N
Liquid B2672
B2477
(CF3SO2)2N
N
N
FeCl4
N
N
CH3
N
Cl
B2473
N N
N
I N
CH3
N
CH3
CH2CH2CH3
Liquid
CH2CH3
N N
Solid
N
(CF3SO2)2N N
CH3
CH3
(CH2)3CH3
Liquid
B2851
N
(CF3SO2)2N
(CH2)3CH3
CH3
N
(CH2)3CH3
Solid
Product No. Product Name D3341 D3240 E0490 E0543 E0556 E0755 E0494 E0836 E0754 E0650 E0680 E0496 E0493 E0599
1,3-Dimethylimidazolium Chloride 1,3-Dimethylimidazolium Dimethyl Phosphate 1-Ethyl-3-methylimidazolium Chloride 1-Ethyl-3-methylimidazolium Bromide 1-Ethyl-3-methylimidazolium Iodide 1-Ethyl-3-methylimidazolium Methanesulfonate 1-Ethyl-3-methylimidazolium Trifluoromethanesulfonate 1-Ethyl-3-methylimidazolium Trifluoro(trifluoromethyl)borate 1-Ethyl-3-methylimidazolium Hydrogen Sulfate 1-Ethyl-3-methylimidazolium Ethyl Sulfate 1-Ethyl-3-methylimidazolium Dicyanamide 1-Ethyl-3-methylimidazolium Tetrafluoroborate 1-Ethyl-3-methylimidazolium Hexafluorophosphate 1-Ethyl-3-methylimidazolium Bis(trifluoromethanesulfonyl)imide (This product is only
E0706 M1440 B2194 B2193 B2708 B2337 B3542 B2195
1-Ethyl-3-methylimidazolium Tetrachloroferrate 1-Methyl-3-propylimidazolium Iodide 1-Butyl-3-methylimidazolium Chloride 1-Butyl-3-methylimidazolium Bromide 1-Butyl-3-methylimidazolium Iodide 1-Butyl-3-methylimidazolium Trifluoromethanesulfonate 1-Butyl-3-methylimidazolium Trifluoro(trifluoromethyl)borate 1-Butyl-3-methylimidazolium Tetrafluoroborate
Liquid
Unit Size 5g
5g 5g 25g 5g 5g 5g 5g 5g 5g 1g 5g 5g 5g
available for selling domestically in Japan)
6
CH3
PF6
mp 38 ℃
Br CH3
CH3
(CH2)3CH3
fp 32 ℃
(CH2)3CH3
Liquid B3159
BF4
(CH2)3CH3
Cl N
CH3
Liquid
CH3
B3427
(CF3SO2)2N
N
(CH2)7CH3
CH3
mp 99 ℃ B3358
M2098
CH3
N
CH3 (CF3SO2)2N
PF6
B2474
CH3
(CH2)3CH3
Solid
N
Liquid
Cl
CH3
CH3
N
B2475
CH3
CH2CH2CH3
N
Br
Liquid
Liquid E0753
N
(CH2)7CH3
Liquid D3903
Liquid
CH3
N
BF4
N
(CH2)5CH3
M2063
N
(CH2)7CH3
(CH2)5CH3
Br
N
CH3
N
Liquid
CH3
N
CH3
(CH2)5CH3
M1904
PF6
N
Cl
Liquid M2062
H1098
N
(CH2)5CH3
Liquid
Liquid H1099
CH3
N
(CH2)3CH3
(CH2)3CH3
Liquid H1227
CH3
N
PF6
N (CH2)3CH3
Liquid H1097
CH3
BF4
(CH2)3CH3
Liquid
CH3
N
N
(CH2)3CH3
(CH2)3CH3
CH3
N CF3BF3
N
N
(CH2)3CH3
N
CH3
CF3SO3
I
B2320
B2195
5g
5g 25g 5g 5g 5g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
25g 25g 250g 25g 25g 25g 25g 5g 25g 25g 5g 25g 25g 25g 5g 25g 100g 5g 25g 25g 5g 25g
Ionic Liquids
Product No. Product Name
Unit Size
B2320 B2477
1-Butyl-3-methylimidazolium Hexafluorophosphate 1-Butyl-3-methylimidazolium Bis(trifluoromethanesulfonyl)imide (This product is only
5g
25g
available for selling domestically in Japan)
B2672 H1097 H1227 H1099 H1098 M2062 M1904 M2063 E0753
1-Butyl-3-methylimidazolium Tetrachloroferrate 1-Hexyl-3-methylimidazolium Chloride 1-Hexyl-3-methylimidazolium Bromide 1-Hexyl-3-methylimidazolium Tetrafluoroborate 1-Hexyl-3-methylimidazolium Hexafluorophosphate 1-Methyl-3-n-octylimidazolium Chloride 1-Methyl-3-n-octylimidazolium Bromide 1-Methyl-3-n-octylimidazolium Hexafluorophosphate 1-Ethyl-2,3-dimethylimidazolium Bis(trifluoromethanesulfonyl)imide (This product is
5g 5g 5g 5g 5g 5g 5g 5g 5g
25g 25g 25g 25g 25g 25g 25g 25g 25g
D3903 B2473 B2475 B2474 B3159
1,2-Dimethyl-3-propylimidazolium Iodide 1-Butyl-2,3-dimethylimidazolium Chloride 1-Butyl-2,3-dimethylimidazolium Tetrafluoroborate 1-Butyl-2,3-dimethylimidazolium Hexafluorophosphate 1-Butyl-2,3-dimethylimidazolium Bis(trifluoromethanesulfonyl)imide (This product is
5g 5g 5g 5g 5g
25g 25g 25g 25g 25g
M2098 B3358 B3427 B2851
1-Methyl-1-propylpyrrolidinium Bis(trifluoromethanesulfonyl)imide 1-Butyl-1-methylpyrrolidinium Chloride 1-Butyl-1-methylpyrrolidinium Bromide 1-Butyl-1-methylpyrrolidinium Bis(trifluoromethanesulfonyl)imide
5g 5g 5g 5g 5g
25g 25g 25g 25g 25g
only available for selling domestically in Japan)
only available for selling domestically in Japan)
B3424
Br
Piperidinium Salts
N
CH3
(CH2)3CH3
mp 230 ℃
Product No. Product Name B3424
Unit Size
1-Butyl-1-methylpiperidinium Bromide
5g
E0544
E0171
Cl
N
Pyridinium Salts
B1329
N
Solid B3232
B1743
Br
B2196
(CH2)3CH3
mp 120 ℃ B3425
Solid B3104
CH3 Br N
BF4
N (CH2)3CH3
(CH2)3CH3
mp 104 ℃
Liquid
CH3 N
CH2CH3
N
Liquid
N
Solid
CH3 Br
Cl N
(CH2)3CH3
mp 160 ℃
Solid B2701
CH3
N
Br
(CH2)3CH3
B2700
CH3CH2OSO3
Liquid
Cl
mp 75 ℃
CH3
CH2CH3
CH3
(CH2)3CH3
B3426 CH2OH
CH3CH2OSO3
N
(CH2)3CH3
E0682
E0681
PF6
N
Cl
N
CH2CH3
CH2CH3
25g
PF6 N
(CH2)3CH3
(CH2)3CH3
mp 137 ℃
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
mp 42 ℃
7
Ionic Liquids
Product No. Product Name E0544 E0171 B1329 B1743 B3232 B2196 B3425 B3104 E0681 E0682 B3426 B2700 B2701
Unit Size
1-Ethylpyridinium Chloride 1-Ethylpyridinium Bromide 1-Butylpyridinium Chloride 1-Butylpyridinium Bromide 1-Butylpyridinium Tetrafluoroborate 1-Butylpyridinium Hexafluorophosphate 1-Butyl-3-methylpyridinium Chloride 1-Butyl-3-methylpyridinium Bromide 1-Ethyl-3-methylpyridinium Ethyl Sulfate 1-Ethyl-3-(hydroxymethyl)pyridinium Ethyl Sulfate 1-Butyl-4-methylpyridinium Chloride 1-Butyl-4-methylpyridinium Bromide 1-Butyl-4-methylpyridinium Hexafluorophosphate
5g 10g 5g 5g 5g 1g 5g 5g 5g 5g 5g
A2274
T2679
CH3 N
(CF3SO2)2N
CH3(CH2)3 N
C1966
(CH2)3CH3 Br
CH3 N
CH3
H1047
T2564
T2680
(CH2)3CH3 CH3(CH2)3 P
(CH2)3CH3 Br
(CH2)3CH3
(CF3SO2)2N
Liquid
mp 70 ℃
(CH2)3CH3
N CH3
(CF3SO2)2N
mp 103 ℃
Liquid
CH3
(CH2)7CH3
(CH2)3CH3
(CH2)3CH3 Cl
(CH2)3CH3
T1124
(CH2)7CH3
(CH2)3CH3 CH3(CH2)3 N
(CF3SO2)2N
Liquid
(CH2)7CH3
(CH2)3CH3
(CH2)3CH3
(CH2)3CH3
CH2CH3
M1660
T0054
T0055 (CH2)3CH3
CH2CH3 CH3(CH2)4 N CH2CH3
Ammonium, Phosphonium, Sulfonium Salts
25g 25g 25g 25g 25g 25g 5g 25g 25g 5g 25g 25g 25g
CH3
P
(CH2)3CH3
(CH2)3CH3 (CF3SO2)2N
Solid
mp 104 ℃
Liquid
T2314
(CH2)3CH3 CH3OCH2CH2 P
(CH2)3CH3
(CH2)3CH3
(CH2)3CH3
CH3(CH2)3 P
CH2CH3
(CH2)15CH3 Br
(CH2)3CH3
CH3CH2
S
(CF3SO2)2N CH2CH3
(CF3SO2)2N
Liquid
mp 61 ℃
Liquid
Product No. Product Name A2274 T2679 T0055 T0054 M1660 C1966 T1124 T2680 T2564 H1047 T2314
Amyltriethylammonium Bis(trifluoromethanesulfonyl)imide Tributylmethylammonium Bis(trifluoromethanesulfonyl)imide Tetrabutylammonium Chloride Tetrabutylammonium Bromide Methyltri-n-octylammonium Bis(trifluoromethanesulfonyl)imide Cyclohexyltrimethylammonium Bis(trifluoromethanesulfonyl)imide Tetrabutylphosphonium Bromide Tributylmethylphosphonium Bis(trifluoromethanesulfonyl)imide Tributyl(2-methoxyethyl)phosphonium Bis(trifluoromethanesulfonyl)imide Tributylhexadecylphosphonium Bromide Triethylsulfonium Bis(trifluoromethanesulfonyl)imide
Unit Size 5g 5g 25g
25g
Pyridinium Compounds (see also p.345) Quaternary Ammonium Compounds (see also p.337) Phosphonium Compounds (see also p.350)
8
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
5g 25g 25g 500g 5g 5g 500g 5g 5g 25g 5g
Ionic Liquids
References 1) T. Welton, . 1999, , 2071; J. D. Holbrey, K. R. Seddon, . 1999, , 223; P. Wasserscheid, W. 2001, Keim, . 2000, , 3772; T. Kitazume, , 5; T. Kitazume, 2001, 2002, , 15; R. Sheldon, . 2001, 2399; D. Zhao, M. Wu, Y. Kou, E. Min, , 157. 2000, 2) M. Freemantle, , 37. 3) R. T. Carlin, H. C. De Long, J. Fuller, P. C. Trulove, . 1994, , L73; A. B. McEwen, S. F. McDevitt, V. R. Koch, . 1997, , L84. 2001, 4) M. Watanabe, A. Noda, T. Kaneko, R. Kawano, , 281; A. Noda, M. Watanabe, 2000, , 1265. 2005, , 29. 5) S. Hayashi, H. Hamaguchi, . 2004, , 1590; H. Hamaguchi,
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
9
Ionic Liquids
Physical Physical Properties Properties of Ionic of Ionic Liquids Liquids (contd.) Elec. Window / V
Cathode Limit / V
Anode Limit / V
Conductivity / S/m
Dynamic Viscosity / cp
Decomposition Point /
℃ Melting Point /
Refractive Index nD20
Specific Gravity
Anion
Cation
Name
Product Code
℃
4.1
-2.2
1.9
IMIDAZOLIUM SALTS D3341 1,3-Dimethylimidazolium Chloride
C1MI
Cl
1,3-Dimethylimidazolium D3240 Dimethyl Phosphate
C1MI
Me2PO4 1.26
E0490
1-Ethyl-3-methylimidazolium Chloride
EMI
Cl
84
281
0.3-3.7
E0543
1-Ethyl-3-methylimidazolium Bromide
EMI
Br
74
311
1.4
E0556
1-Ethyl-3-methylimidazolium Iodide
EMI
I
79
303
E0755
1-Ethyl-3-methylimidazolium Methanesulfonate
EMI
MsO
1.25
1.50
5
80
E0494
1-Ethyl-3-methylimidazolium Trifluoromethanesulfonate
EMI
TfO
1.39
1.43
-9
45
0.92
E0836
1-Ethyl-3-methylimidazolium Trifluoro(trifluoromethyl)borate
EMI
CF3BF3
1.35
26
1.48
E0754
1-Ethyl-3-methylimidazolium Hydrogen Sulfate
EMI
HSO4
1.38
1.50
Liquid
E0650
1-Ethyl-3-methylimidazolium Ethyl Sulfate
EMI
EtSO4
1.24
1.48
Liquid
E0680
1-Ethyl-3-methylimidazolium Dicyanamide
EMI
(NC)2N
1.11
1.52
-21
240
21
2.2
E0496
1-Ethyl-3-methylimidazolium Tetrafluoroborate
EMI
BF4
1.29
15
391
38
1.4
E0493
1-Ethyl-3-methylimidazolium Hexafluorophosphate
EMI
PF6
61
375
E0599
1-Ethyl-3-methylimidazolium Bis(trifluoromethanesulfonyl)imide
EMI
TFSI
-15
453
33
E0706
1-Ethyl-3-methylimidazolium Tetrachloroferrate
EMI
FeCl4
Liquid
M1440 1-Methyl-3-propylimidazolium Iodide
C3MI
I
Liquid
B2194
1-Butyl-3-methylimidazolium Chloride
BMI
Cl
254
280
B2193
1-Butyl-3-methylimidazolium Bromide
BMI
Br
B2708
1-Butyl-3-methylimidazolium Iodide
BMI
I
1.44 1.57d
-72
B2337
1-Butyl-3-methylimidazolium Trifluoromethanesulfonate
BMI
TfO
1.31
13
B3542
1-Butyl-3-methylimidazolium Trifluoro(trifluoromethyl)borate
BMI
CF3BF3
1.27
B2195
1-Butyl-3-methylimidazolium Tetrafluoroborate
BMI
BF4
1.21
1.42
-81
403
219
B2320
1-Butyl-3-methylimidazolium Hexafluorophosphate
BMI
PF6
1.37
1.41
10
349
450
0.15
5
-2
3
B2477
1-Butyl-3-methylimidazolium Bis(trifluoromethanesulfonyl)imide
BMI
TFSI
1.44 1.43d
-2
402
52
0.39
4.62
-2.5
2.12
B2672
1-Butyl-3-methylimidazolium Tetrachloroferrate
BMI
FeCl4
H1097 1-Hexyl-3-methylimidazolium Chloride
C6MI
Cl
253
716
H1227 1-Hexyl-3-methylimidazolium Bromide
C6MI
Br
10
125 1.49
Liquid
-20
1.53
11.9
41
246
4.63 -2.49 2.14
98 3.0
-1.6
1.4
4.55 -2.45 2.10
0.52 0.83
4.6
-2.5
2.1
Liquid
1.44
265 1110
Liquid 238
90
0.37b
49
0.59 4.68 -2.55 2.13
Liquid 1.03
1.52
-75
1.54
Liquid
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Ionic Liquids
Physical Properties of Ionic Liquids (contd.) Dynamic Viscosity / cp
Conductivity / S/m
1.43
-82
409
310
0.12
H1098
1-Hexyl-3-methylimidazolium Hexafluorophosphate
C6MI
PF6
1.29
1.42
-61
M2062 1-Methyl-3-n-octylimidazolium Chloride
C8MI
Cl
M1904 1-Methyl-3-n-octylimidazolium Bromide
C8MI
Br
M2063
1-Methyl-3-n-octylimidazolium Hexafluorophosphate
C8MI
PF6
1.24
1.42
E0753
1-Ethyl-2,3-dimethylimidazolium Bis(trifluoromethanesulfonyl)imide
EDMI
TFSI
1.50
1.43
DMPI
I
D3903 1,2-Dimethyl-3-propylimidazolium Iodide
1.51
12
Anion
Anode Limit / V
Decomposition Point /
1.15
Cathode Limit / V
Melting Point /
BF4
℃
Elec. Window / V
Refractive Index nD20
C6MI
Cation
1-Hexyl-3-methylimidazolium Tetrafluoroborate
Name
H1099
Product Code
Specific Gravity
℃
6
-3
3
560 243
337
-70
376
682
27
456
88
Liquid
0.32b
Solid
B2473
1-Butyl-2,3-dimethylimidazolium Chloride BDMI
Cl
B2475
1-Butyl-2,3-dimethylimidazolium Tetrafluoroborate
99
BDMI
BF4
1.20
37
B2474
1-Butyl-2,3-dimethylimidazolium Hexafluorophosphate
BDMI
PF6
1.24
38
B3159
1-Butyl-2,3-dimethylimidazolium Bis(trifluoromethanesulfonyl)imide
BDMI
TFSI
1.43
1.44
1.43
780
Liquid
PYRROLIDINIUM SALTS M2098
1-Methyl-1-propylpyrrolidinium Bis(trifluoromethanesulfonyl)imide
P13
TFSI
B3358
1-Butyl-1-methylpyrrolidinium Chloride
P14
Cl
Solid
B3427
1-Butyl-1-methylpyrrolidinium Bromide
P14
Br
214
B2851
1-Butyl-1-methylpyrrolidinium Bis(trifluoromethanesulfonyl)imide
P14
TFSI
PP14
Br
230
1.40
12
1.42
340
-18
61
0.14
85
0.22
PIPERIDINIUM SALTS B3424
1-Butyl-1-methylpiperidinium Bromide
E0544
1-Ethylpyridinium Chloride
Epy
Cl
Solid
E0171
1-Ethylpyridinium Bromide
Epy
Br
120
B1329
1-Butylpyridinium Chloride
Bpy
Cl
Solid
B1743
1-Butylpyridinium Bromide
Bpy
Br
B3232
1-Butylpyridinium Tetrafluoroborate
Bpy
BF4
PYRIDINIUM SALTS
104 1.22
1.45
-1
342
75
B2196
1-Butylpyridinium Hexafluorophosphate
Bpy
PF6
B3425
1-Butyl-3-methylpyridinium Chloride
C4Mpy
Cl
B3104
1-Butyl-3-methylpyridinium Bromide
C4Mpy
Br
Solid
E0681
1-Ethyl-3-methylpyridinium Ethyl Sulfate
C2Mpy
EtSO4
Liquid
E0682
1-Ethyl-3-(hydroxymethyl)pyridinium Ethyl Sulfate
C2HMpy EtSO4
B3426
1-Butyl-4-methylpyridinium Chloride
C4M'py Cl
160
B2700
1-Butyl-4-methylpyridinium Bromide
C4M'py Br
137
B2701
1-Butyl-4-methylpyridinium Hexafluorophosphate
C4M'py PF6
Solid
1.51
199
Liquid
42
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
11
Ionic Liquids
Physical Properties of Ionic Liquids (contd.)
T2679
Tributylmethylammonium Bis(trifluoromethanesulfonyl)imide
N1444
TFSI
1.27
1.43
Liquid
T0055
Tetrabutylammonium Chloride
N4444
Cl
70
T0054
Tetrabutylammonium Bromide
N4444
Br
103
N1888
TFSI
-
TFSI
Solid
104
Melting Point /
Anion
Anode Limit / V
Liquid
Cathode Limit / V
1.43
Elec. Window / V
1.32
Conductivity / S/m
TFSI
℃
Dynamic Viscosity / cp
Refractive Index nD20
N5222
Cation
Amyltriethylammonium Bis(trifluoromethanesulfonyl)imide
Name
A2274
Product Code
Specific Gravity
Decomposition Point /
℃
AMMONIUM SALTS
Methyltri- -octylammonium M1660 Bis(trifluoromethanesulfonyl)imide C1966
Cyclohexyltrimethylammonium Bis(trifluoromethanesulfonyl)imide
1.11
1.44
-39
386
367
589
PHOSPHONIUM SALTS T1124
Tetrabutylphosphonium Bromide
P4444
Br
T2680
Tributylmethylphosphonium Bis(trifluoromethanesulfonyl)imide
P4441
TFSI
1.26
1.44
16
T2564
Tributyl(2-methoxyethyl)phosphonium Bis(trifluoromethanesulfonyl)imide
P444,2O1 TFSI
1.25
1.44
10
H1047 Tributylhexadecylphosphonium Bromide
P444,16 Br
0.042
61
SULFONIUM SALTS T2314
Triethylsulfonium Bis(trifluoromethanesulfonyl)imide
S222
TFSI
1.47
1.43
-36
30
The values of physical properties are based on literatures except those of refractive index unless otherwise noted. Please note that those values are not specification details which could vary with lot number of each product. References: 1) S. Zhang, X. Lu, Q, Zhou, X. Li, X. Zhang, S. Li, in 2) S. Zhang, N. Sun, X. He, X. Lu, X. Zhang, Notes: a 25 ℃ , b 20 ℃ , c 64.9 ℃ , d ref. 1, e 30 ℃
12
, Elsevier, Oxford, 2009. 2006,
, 1475.
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Fluorous Chemistry
Fluorous Chemistry In recent years, fluorous chemistry has emerged as one of the promising fields of green chemistry. The term“fluorous”is a coined word meaning having affinity with fluorocarbons. Highly fluorinated compounds, in another words fluorous compounds, are insoluble in general organic solvents or water. However they are highly soluble with fluorous solvents such as perfluoroalkane. Fluorous chemistry is the technique of making use of this property, and it is applied to many organic reactions. Although fluorous solvents are generally immiscible with common organic solvents and water, certain fluorous solvents are able to form homogeneous solutions with some organic solvents at elevated temperatures. The characteristic features of these fluorous solvents is that they have boiling points properties that are almost equal to those of the corresponding hydrocarbons, regardless of their molecular weight, and these solvents have a high solubility of many gases and incombustible property. Taking the advantage of these properties, Horváth . accomplished the hydroformylation of olefins using a fluorous rhodium catalyst in perfluoromethylcyclohexane and toluene in 1994.1) This was regarded as the origin of the fluorous chemistry. This reaction uses perfluoromethylcyclo hexane and toluene as solvents, which exist as a biphasic system at room temperature. In this system the fluorous catalyst exists in the fluorous phase and the olefins in the organic phase. However, the two phases form a homogeneous solution when heated. The reaction then proceeds by introduction of carbon monoxide and hydrogen gases. When the reaction is complete and the system is cooled, the two phases reappears, where the resulting product is found in the organic phase and the fluorous catalyst is in the fluorous phase; thus, the catalyst and the product are easily separated. The biphasic system using a fluorous solvent and an organic solvent is called Fluorous Biphase System (FBS), and the multiple phase system is called Fluorous Multiphase System (FMS). The advantages of FBS and FMS are that the resulting product and the catalyst can be easily separated simply by separating the fluorous phase from the other phase after the reaction. After separation, the fluorous phase containing the fluorous catalyst can be reused. room temp.
room temp. Heat
Cool
Substrate
Product
Catalyst
Catalyst
organic solvent fluorous solvent
Homogeneous
1)
Rh(CO)2(acac) P[(CH2)2(CF2)5CF3]3 CO / H2 (1:1, 150 psi)
C8H17
CH3 CHO
C8H17
CF3C6F11 / Toluene 100 °C, 2 h
C8H17
CHO
Y. 85%
Curran . have introduced the use of fluorous substituents (fluorous tags) into non-fluorous substrates for the synthesis of isoxazoline.2) After the reaction, the fluorous product was separated by fractional extraction with dichloromethane, water, and perfluorohexane. Following this report, numerous applications of fluorous chemistry have been made in combinatorial chemistry3) and oligosaccharide syntheses4). D2669
E0485
P0074
(CF2)3CF3
H0946
CF3(CF2)7CF3
CF3CHFCHFCF2CF3
Fluorous Solvents
H0085
P0837 F F
F
F
F
CF3(CF2)7Br F
F
O0268 F
F F F
F
F
F
F F
F
F F F
F
F
(CF2)3CF3
O0292
F
F
N
CF3(CF2)3
CF3(CF2)6CF3
F
F
F
F
F
F F
F
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
13
Fluorous Chemistry
P0856
P1420 CF3 F
F
F
F
P0851
F
F F
F
CF3
F
F
F
CF3(CF2)5CF3
C5F11 C5F11 N C5F11
F
F
F
F F
F
CF3CF2CF2CF
CF3 CF3
F
Product No. Product Name
Unit Size
2H,3H-Decafluoropentane Eicosafluorononane Heptacosafluorotributylamine Heptadecafluoro-n-octyl Bromide Hexafluorobenzene Octadecafluorodecahydronaphthalene Octadecafluorooctane Octafluorocyclopentene Octafluorotoluene Perfluoro(2-butyltetrahydrofuran) (so called) Perfluoro(1,3-dimethylcyclohexane) Perfluoroheptane (mixture of isomers) Perfluorotriamylamine (so called) Perfluorotriethylamine Tetradecafluorohexane Tetradecafluoromethylcyclohexane Tetradecafluoro-2-methylpentane
25g
5g 25g
5g
10g
Fluorous Alkanes, Fluorous Alkenes
Fluorous Compounds
T2496
14
CF3(CF2)7CH CH2
500g 10g 25g 25g 250g 25g 10g 50g 25g 25g 25g 25g 25g 25g 250g 25g 25ml
N0601
CF3(CF2)3CH CH2
U0076
CF3(CF2)4CHF2
Product No. Product Name H0846 N0601 P1102 T2496 U0076
5g 25g
10g
H0846
CF3(CF2)5CH CH2
CF2CF3
CF3 F
F F
P1102
N
T1012 F
D2669 E0485 P0074 H0946 H0085 P0837 O0268 O0292 P0856 P0867 P1420 P0851 P1051 P1348 P0839 P0846 T1012
CF2CF3 CF3CF2
F
P0846
CF3(CF2)4CF3
P1348
CF3
F F
P0839
F
P1051
1H,1H,2H-Heptadecafluoro-1-decene 3,3,4,4,5,5,6,6,6-Nonafluoro-1-hexene (Perfluorohexyl)ethylene 1H-Tridecafluorohexane 1H-Undecafluoropentane
CF3(CF2)3CHF2
Unit Size 5g 5g 10g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
25g 25g 25g 5g 5g
Fluorous Chemistry
D1101
Fluorous Alcohols
H1232
H(CF2)6CH2OH
H0548
D2891
HOCH2(CF2)6CH2OH
H1233
E0239
H0845
H(CF2)10CH2OH
H1035
CF3(CF2)7CH2CH2OH
H1279
F3C CF3 CF3(CF2)7CH2OH
CF3CF2CF2CH2OH
HOCH2(CF2)8CH2OH
H(CF2)8CH2OH
HO C C OH F3C CF3
H0649
H0746
CF3CHFCF2CH2OH
O0294
HOCH2(CF2)3CH2OH
O0114
HOCH2(CF2)4CH2OH
CHF2(CF2)3CH2OH
N0814
CF3(CF2)8CH2OH
P0904
CF3(CF2)6CH2OH
N0600
CF3(CF2)3CH2CH2OH
P0845
N0810
CF3(CF2)3CH2OH
T1701
CF3CF2CH2OH
CF3(CF2)5CH2OH
T2528
CF3(CF2)5CH2CH2OH
Product No. Product Name D1101 D2891 E0239 H0845 H1232 H0548 H1233 H1035 H1279 H0649 H0746 N0814 N0600 N0810 O0294 O0114 P0904 P0845 T1701 T2528
1H,1H,7H-Dodecafluoro-1-heptanol 2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-1,8-octanediol 1H,1H,11H-Eicosafluoro-1-undecanol 1H,1H,2H,2H-Heptadecafluoro-1-decanol 1H,1H-Heptadecafluoro-1-nonanol 2,2,3,3,4,4,4-Heptafluoro-1-butanol 1H,1H,10H,10H-Hexadecafluoro-1,10-decanediol 1H,1H,9H-Hexadecafluoro-1-nonanol Hexafluoro-2,3-bis(trifluoromethyl)-2,3-butanediol 2,2,3,4,4,4-Hexafluoro-1-butanol 2,2,3,3,4,4-Hexafluoro-1,5-pentanediol 1H,1H-Nonadecafluoro-1-decanol 1H,1H,2H,2H-Nonafluoro-1-hexanol 1H,1H-Nonafluoro-1-pentanol 2,2,3,3,4,4,5,5-Octafluoro-1,6-hexanediol 2,2,3,3,4,4,5,5-Octafluoro-1-pentanol 1H,1H-Pentadecafluoro-1-octanol 2,2,3,3,3-Pentafluoro-1-propanol 1H,1H-Tridecafluoro-1-heptanol 1H,1H,2H,2H-Tridecafluoro-1-n-octanol
Unit Size 25g
25g 5g 1g 5g 1g 5g 5g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
250g 5g 10g 250g 5g 25g 5g 25g 25g 25g 5g 5g 25g 1g 25g 500g 5g 25g 5g 25g
15
Fluorous Chemistry
P1449
Fluorous Carboxylic Acids, Anhydrides and Halides H0024
B1698
O
O
H0743
C
CF3CF2CF2
T2492
O (CF2)8
O HO C
O CF3(CF2)3 C F
O HO C
O
Unit Size
D3589
D3590
O
16
CH3O C
O
CF3(CF2)4 C F
Ammonium Pentadecafluorooctanoate 2,5-Bis(trifluoromethyl)-3,6-dioxaundecafluorononanoyl Fluoride Dodecafluorosuberic Acid Heptadecafluorononanoic Acid Heptafluorobutyric Acid Heptafluorobutyric Anhydride Heptafluorobutyryl Chloride [for Heptafluorobutyration] Hexadecafluorosebacic Acid Hexafluoroglutaric Acid 2,2,3,3,4,4-Hexafluoropentanedioyl Dichloride Nonadecafluorodecanoic Acid Nonafluorovaleric Acid Nonafluorovaleryl Fluoride Octafluoroadipic Acid Pentadecafluorooctanoic Acid Hydrate Tricosafluorododecanoic Acid Tridecafluoroheptanoic Acid Undecafluorohexanoic Acid Undecafluorohexanoyl Fluoride
Fluorous Esters
C OH
(CF2)4 C OH
O
Product No. Product Name P1449 B1698 D2465 H0843 H0024 H0337 H0508 H0892 H0658 H0743 N0607 N0605 N0809 O0260 P0764 T2492 T1545 U0067 U0075
O (CF2)3
U0075
CF3(CF2)4 C OH
CF3(CF2)5 C OH
C OH
O0260
O
CF3(CF2)10 C OH
C OH
U0067
O
. xH2O
O HO C
CF3(CF2)3 C OH
T1545
O CF3(CF2)6 C OH
CF3(CF2)7
H0658
O
CF3(CF2)8 C OH
O
O (CF2)6 C OH
N0809
O
P0764
C Cl
N0605
O (CF2)3 C Cl
HO C
O
N0607
O
C F
H0892
O
CF3CF2CF2 C O C CF2CF2CF3
H0843
O
CF3 O
CF3(CF2)2O CF CF2O CF
H0508
O
Cl
CF3
CF3(CF2)6 C O NH4
H0337
CF3CF2CF2 C OH
D2465
O (CF2)3 C OCH3
5g 5g 25g 5g 5g 1g 5g 5g 10g 1g 5g 5g
H1038
O CH3O C
25g 5g 25g 25g 100g 10g 25g 25g 10g 5g 5g 25g 5g 25g 25g 5g 25g 25g 5g
H0594
O
O
(CF2)4 C OCH3
CF3(CF2)7 C OCH2CH3
O CF3CF2CF2 C OCH2CH3
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Fluorous Chemistry
N0689
H0744
O
M1915
O
CF3(CF2)3 C OCH2CH3
M1916
CH3CH2O C
M1912
CF3(CF2)7 C OCH3
P1453
O
CF3(CF2)3 C OCH3
CF3(CF2)2 C OCH3
M1917
O
O
CF3(CF2)8 C OCH3
M2022
O
O
O (CF2)3 C OCH2CH3
H1033
CF3(CF2)6 C OCH3
O (CF3)2CF C OCH3
M1914
O CF3(CF2)10 C OCH3
O CF3(CF2)5 C OCH3
M1913
O CF3(CF2)4 C OCH3
Product No. Product Name D3589 D3590 H1038 H0594 N0689 H0744 M1915 H1033 M2022 M1916 M1912 P1453 M1917 M1914 M1913
D3572
D3573
Br(CF2)6Br
Fluorohalides
H0844
H1084
CF3(CF2)9I
Unit Size
Dimethyl Hexafluoroglutarate Dimethyl Octafluoroadipate Ethyl Heptadecafluorononanoate Ethyl Heptafluorobutyrate Ethyl Nonafluorovalerate 2,2,3,3,4,4-Hexafluoropentanedioic Acid Diethyl Ester Methyl Heptadecafluorononanoate Methyl Heptafluorobutyrate Methyl Heptafluoroisobutyrate Methyl Nonadecafluorodecanoate Methyl Nonafluorovalerate Methyl Pentadecafluorooctanoate Methyl Tricosafluorododecanoate Methyl Tridecafluoroheptanoate Methyl Undecafluorohexanoate
CF3(CF2)7CH2CH2I
1g 1g 5g
5g 5g 5g
5g 5g
D2804
Br(CF2)4Br
H0946
D2333
Cl(CF2)8Cl
P1084
CF3(CF2)7Br
5g 5g 5g 25g 5g 1g 25g 25g 25g 25g 5g 5g 25g 25g 5g
I(CF2)6I
H0689
CF3(CF2)7I
CF3CF2CF2Br
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
17
Fluorous Chemistry
H0596
N0808
N0499
CF3(CF2)8Br
CF3CF2CF2I
P1753
T2479
CF3(CF2)6Br
P1155
CF3CF2CF2CF2I
T1098
I(CF2)4I
CF3(CF2)3CH2CH2I
T2482
CF3(CF2)4CF2I
CF3(CF2)5Br
D2329
T2074
CF3(CF2)5CH2I
CF3(CF2)5CH2CH2I
U0081
CF3(CF2)4I
Product No. Product Name D3572 D3573 D2804 D2333 H0844 H1084 H0946 P1084 H0689 H0596 N0808 N0499 P1155 D2329 P1753 T2479 T1098 T2482 T2074 U0081
Unit Size
1,6-Dibromododecafluorohexane 1,4-Dibromooctafluorobutane 1,8-Dichlorohexadecafluorooctane Dodecafluoro-1,6-diiodohexane Heneicosafluorodecyl Iodide 1H,1H,2H,2H-Heptadecafluorodecyl Iodide Heptadecafluoro-n-octyl Bromide Heptadecafluoro-n-octyl Iodide Heptafluoropropyl Bromide Heptafluoropropyl Iodide (stabilized with Copper chip) Nonadecafluorononyl Bromide Nonafluorobutyl Iodide 1H,1H,2H,2H-Nonafluorohexyl Iodide Octafluoro-1,4-diiodobutane Pentadecafluoroheptyl Bromide Tridecafluorohexyl Bromide Tridecafluorohexyl Iodide 1H,1H-Tridecafluoro-1-iodoheptane 1H,1H,2H,2H-Tridecafluoro-n-octyl Iodide Undecafluoropentyl Iodide
H0781
Fluorous Sulfonic Acids & their derivatives N0710
O O
5g 5g 5g
5g 25g 5g
5g
5g 5g
H1281
O CF3(CF2)7 S
N0677
O CF3(CF2)3 S OH O
H1055
O
F
CH3
S OCH O
O
O
N0709
CF3(CF2)3 S OLi
18
S OH
P1098
O CF3(CF2)3 S OCH2CF3 O
5g 5g 25g 10g 25g 25g 25g 25g 5g 25g 5g 500g 25g 10g 5g 25g 25g 1g 25g 25g
5g
H1176
O CF3(CF2)7
1g
CF3 CF3
O CF3(CF2)7 S OLi O
H0729
O
O CF3(CF2)3 S
F
CF3(CF2)7 S OK
O
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
O
Fluorous Chemistry
N0711
O CF3(CF2)3 S OK O
Product No. Product Name H0781 H1176 H1281 H1055 N0710 N0709 N0677 P1098 H0729 N0711
Unit Size
Heptadecafluorooctanesulfonic Acid Heptadecafluoro-1-octanesulfonyl Fluoride 1,1,1,3,3,3-Hexafluoroisopropyl p-Toluenesulfonate Lithium Heptadecafluoro-1-octanesulfonate Lithium Nonafluoro-1-butanesulfonate Nonafluoro-1-butanesulfonic Acid Nonafluorobutanesulfonic Acid 2,2,2-Trifluoroethyl Ester Perfluorobutanesulfonyl Fluoride Potassium Heptadecafluoro-1-octanesulfonate Potassium Nonafluoro-1-butanesulfonate
B2340
E0462
O
Other Fluorous Compounds H0926
C CF2CF2CF3
O
O
U0071
N0645
F
F F O S
F F S O N H O
F
O
F F S O N Li O
P1080
CH2 CH
O
C OCH2(CF2)4H
P1081
CH2 CH C OCH2(CF2)6CF3
H1058
O
F
O S CF3
P1163
O CH2CH2CH3
I
O S CF3 O
T2037
CH3CH2CH2
CF3(CF2)7 S N CH2CHCH2OH O
OH
CH2 O
O
CF3(CF2)3SO2 CF3(CF2)3SO2
NK
T1770 O
O N S
CH3
O CF3(CF2)7
O
F F F S O N O K
I
O
P1162
F F O S
CF3(CF2)5
CH2 C C OCH2(CF2)4H
N0712
O CH2O(CH2)2(CF2)5CF3
O CF3(CF2)6 C CH3
M1433
O
P1106
CH C OCH2CH2(CF2)7CF3
F
O0318
CF3(CF2)3CH2NH2
CF3(CF2)3 C CH3
O
O CH2
P1452
O
CF3(CF2)4 C CH3
P1754
F
N0872
O
O
H1057
F F O S
N
CF3CF2CF2 C NH2
A1330
CF3(CF2)4 C CH2CH3
H1056 N
O
25g
CH2(CF2)7CF3 O
25g 250g 25g 25g 25g 25g 5g 250g 25g 25g
5g
P1363
O
CH2 CH C OCH2(CF2)4CH2O C CH CH2
H0467
1g 25g 5g
(CF2)7CF3
CH2
C
(CF2)6CF3
C
(CF2)6CF3
OCH2CH3 CF3(CF2)5CH2CH2 Si OCH2CH3 OCH2CH3
O
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
19
Fluorous Chemistry
T2720
T0859
T0829
P1134 (CF2)8CF3
CF2CF2CF3
OCH3 CF3CH2CH2 Si OCH3 OCH3
N CF3CF2CF2
N
N N
CF2CF2CF3 CF3(CF2)8
N N
T0828 (CF2)6CF3
O
N
H(CF2)4CH2O P OCH2(CF2)4H
(CF2)8CF3
OCH2(CF2)4H
CF3(CF2)6
N N
(CF2)6CF3
U0083
CF3(CF2)4CH2NH2
Product No. Product Name B2340 E0462 P1363 A1330 H0926 H0467 H1056 H1057 P1452 U0071 N0645 N0872 O0318 M1433 P1754 P1106 P1080 P1081 N0712 H1058 P1162 P1163 T2037 T1770 T2720 T0859 T0829 P1134 T0828 U0083
1,6-Bis(acryloyloxy)-2,2,3,3,4,4,5,5-octafluorohexane 1,2-Epoxy-1H,1H,2H,3H,3H-heptadecafluoroundecane Ethyl Perfluoroamyl Ketone 1H,1H,2H,2H-Heptadecafluorodecyl Acrylate (stabilized with MEHQ) Heptafluorobutyramide 1-(Heptafluorobutyryl)imidazole [Acylating Agent] 1,1,2,2,3,3-Hexafluoropropane-1,3-disulfonimide Lithium 1,1,2,2,3,3-Hexafluoropropane-1,3-disulfonimide Methyl Pentadecafluoroheptyl Ketone Methyl Perfluoroamyl Ketone Methyl Perfluorobutyl Ketone 1H,1H-Nonafluoropentylamine 1H,1H,5H-Octafluoropentyl Acrylate (stabilized with MEHQ) 1H,1H,5H-Octafluoropentyl Methacrylate (stabilized with TBC) 1H,1H-Pentadecafluoro-n-octyl Acrylate (stabilized with MEHQ) 3-[2-(Perfluorohexyl)ethoxy]-1,2-epoxypropane (Perfluorohexyl)phenyliodonium Trifluoromethanesulfonate (Perfluoro-n-octyl)phenyliodonium Trifluoromethanesulfonate Potassium Bisnonafluoro-1-butanesulfonimidate Potassium 1,1,2,2,3,3-Hexafluoropropane-1,3-disulfonimide N-Propyl-N-(2,3-dihydroxypropyl)perfluoro-n-octylsulfonamide N-Propyl-N-(2,3-epoxypropyl)perfluoro-n-octylsulfonamide 9H,9H-Triacontafluoro-8,10-heptadecanedione Triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane Trimethoxy(3,3,3-trifluoropropyl)silane 2,4,6-Tris(heptafluoropropyl)-1,3,5-triazine [for Mass spectrometry] 2,4,6-Tris(nonadecafluorononyl)-1,3,5-triazine [for Mass spectrometry] Tris(1H,1H,5H-octafluoropentyl) Phosphate 2,4,6-Tris(pentadecafluoroheptyl)-1,3,5-triazine [for Mass spectrometry] 1H,1H-Undecafluorohexylamine
Unit Size 1g
5g 1g 1g
1g
5g 1g 5g 5g 5g 1g 1g 1g
5g 5g
1g
5g 10g 5g 10g 25g 25g 5g 5g 5g 5g 25g 5g 25g 25g 25g 25g 5g 1g 5g 5g 25g 25g 100mg 25g 25g 0.1ml 100mg 10g 100mg 5g
References 1994, 1) I. T. Horváth, J. Rábai, , 72. 1997, 2) A. Studer, S. Hadida, R. Ferritto, S.-Y. Kim, P. Jeger, P. Wipf, D. P. Curran, , 823. 3) D. P. Curran, S. Hadida, . 1996, , 2531; D. P. Curran, M. Hoshino, . 1996, , 6480; D. P. Curran, . 1998, , 1174; D. P. Curran, Z. Luo, . 1999, , 9069; Q. Zhang, 2001, Z. Luo, D. P. Curran, . 2000, , 8866; Z. Luo, Q. Zhang, Y. Oderaotoshi, D. P. Curran, , 1766; S. Darses, M. Pucheault, J.-P. Genêt, . 2001, 1121. 4) T. Miura, Y. Hirose, M. Ohmae, T. Inazu, . 2001, , 3947; T. Miura, T. Inazu, . 2003, , 1819. 2001, 5) Reviews: K. Ishihara, H. Yamamoto, , 1061; K. Ishihara, 2002, 2002, , 865; I. Ryu, H. Matsubara, , 20; S. Takeuchi, Y. Nakamura, 2002, 2002, , 16; K. Mikami, H. Matsuzawa, , 22; K. Ishihara, H. Yamamoto, 2002, , 30.
20
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Amphiphilic Polymer-assembled Pd Complex Catalyst
Amphiphilic Polymer-assembled Pd Complex Catalyst Product No. Product Name
P1425
Unit Size
Poly[N-isopropylacrylamide-co-4-(diphenylphosphino)styrene] Palladium(II) Dichloride (ratio, acrylamide:phosphine=20:2) 1
100mg
1g
Palladium is one of the most useful catalysts in organic syntheses. Many types of palladium complex catalysts have been developed and utilized in various reactions. Furthermore,“Environmentally-friendly organic syntheses”are desired these days, so there have been many developmental studies of palladium complex catalysts with respect to green chemistry in recent years. Palladium complex catalyst 1 developed recently by Ikegami . is one of those catalysts with excellent properties. Catalyst 1 is solid-phase catalyst which consists of amphiphilic copolymer ligands and palladium. It uptakes substrates and reagents of both hydrophilic and hydrophobic nature in the vicinity of palladium to smoothly promote the reaction. The palladium complex catalyst forms a networked supermolecular complex, which is insoluble in water and organic solvents, and is easily recovered from reaction system. Since the palladium is firmly held in place by the phosphino group of copolymer ligand, it is not lost during the reaction or upon work up; therefore, the catalyst can be recovered and reused multiple times. Ph P Ph
O HN 20
B(OH)2
X + R'
R'' (1.1 mol eq.)
PdCl2 2
1 (5.0 X 10-4- 5.0 X 10-5 mol eq.) Na2CO3 (1.11 mol eq.), H2O, 100 oC
n
R'
R''
X=I, R'=H, R''=H
1st Y. 95% 10th Y. 93% 1st-10th consecutive use av: 95%
X=Br, R'=4-Me, R''=H Y. 95% X=Br, R'=4-Me, R''=4-MeS Y. 95% X=Br, R7=4-Cl, R''=H Y. 94%
Ikegami . have demonstrated an application of 1 for the Suzuki-Miyaura coupling reaction in water, as this reaction does not require any organic solvents.1) This method requires as little as 5×10‒4∼5×10‒5 mol equiv. of 1 to effectively catalyze the reaction. After the reaction, 1 can be recovered by simple filtration. The recovered catalyst 1 can be reused, and it maintains its catalytic activity even after being reused ten times.
As shown in the figure, in the presence of sodium carbonate and catalyst 1, halobenzene and 1.1 mol equiv. of phenylboronic acid react to form product in water as the solvent. The reaction vessel is fitted with glass filter, and after the reaction is completed, the mixture is filtered while it is still hot and then washed with hot water. The catalyst 1 remains in the reaction vessel, while the filtrate contains the biphenyls, as well as sodium carbonate and residual phenylboronic acid. When the filtrate is cooled, the biphenyls crystallize out of the aqueous phase. Upon filtration, the biphenyls are easily obtained. 1 that remains in the reaction vessel can be reused right away. An application of this catalyst for the Heck reaction has been reported as one example of a reaction in an organic solvent.2) References 1) Y. M. A. Yamada, K. Takeda, H. Takahashi, S. Ikegami, . 2002, , 3371; Y. M. A. Yamada, K. Takeda, H. Takahashi, S. Ikegami, . 2003, , 7733; Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 2003 236388, 2003. 2) Y. M. A. Yamada, K. Takeda, H. Takahashi, S. Ikegami, . 2003, , 2379.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
21
Stable Lewis Acids in Aqueous Media
Stable Lewis Acids in Aqueous Media 1)
OTMS
O
Yb(OTf)3 (20 mol%)
+
HCHO aq.
H2O – THF
Ph
Ph
OH
Y. 1st run 2nd run 3rd run
94% 91% 93%
2)
CHO
Yb(OTf)3 (20 mol%)
+
CHO
CH2Cl2, 0 °C
Y. 1st run 2nd run
77% (exo : endo = 93 : 7) 75% (exo : endo = 92 : 8)
The Lewis acid-catalyzed C-C bond forming reactions have been of great interest in organic synthesis. While various kinds of Lewis acid-promoted reactions have been developed, these reactions must be carried out under strict anhydrous conditions. The presence of even a small amount of water stops the reaction, because most Lewis acid immediately react with water rather than the substrates and decompose or deactivate. Recently, Kobayashi and co-worker have found that certain metal triflates are stable Lewis acids in aqueous media. The reaction of silyl enol ethers with commercial formaldehyde solution smoothly proceeds in aqueous media by the certain metal triflates, especially Yb(OTf)3 to give the corresponding aldol adducts in high yields. Moreover, the triflates can also be used in organic solvents in many reactions. In all cases, the reaction is completed by only a catalytic amount of the triflate, and the catalyst can be easily recovered after the reaction was completed and can be reused. On the other hand, in asymmetric synthesis, chiral Lewis acid which was prepared by Sc(OTf)3, chiral binaphthol and an amine affords chiral Diels-Alder adduct in the reactions of dienophiles and dienes. Then, the certain metal triflates, especially Yb(OTf)3, Sc(OTf)3, etc. are expected to be useful as new types of Lewis acid catalysts in many organic reactions. From the view points of green chemistry, these are also remarkably effective Lewis Acids as non-toxic and nonflammable water can be used as reaction solvent.
T1918
T1292
O CF3
CF3
CF3
T1921
S OAg
O
O
3
CF3
3
CF3
O Tm3
S O O
3
CF3
Yb3
S O O
Zn2
S O O
3
T1610
O Y3
S O O
22
T1920
CF3
La3
S O O
4
O Sc3
S O
CF3
InCl3
T1294
O CF3
O
T1331
O
3
O Hf4
S O
O Nd3
S O O
CF3
2
T1663
O
T1293
O Cu2
S O O
3
T1919
CF3
I0778
O Ce3
S O O
T1708
2
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
3
. xH2O
Stable Lewis Acids in Aqueous Media
Product No. Product Name T1918 T1292 T1708 I0778 T1293 T1919 T1663 T1331 T1920 T1610 T1921 T1294
Cerium(III) Trifluoromethanesulfonate Copper(II) Trifluoromethanesulfonate Hafnium(IV) Trifluoromethanesulfonate Indium(III) Chloride Anhydrous Lanthanum(III) Trifluoromethanesulfonate Neodymium(III) Trifluoromethanesulfonate Scandium(III) Trifluoromethanesulfonate Silver Trifluoromethanesulfonate Thulium(III) Trifluoromethanesulfonate Ytterbium(III) Trifluoromethanesulfonate Hydrate Yttrium(III) Trifluoromethanesulfonate Zinc(II) Trifluoromethanesulfonate
Unit Size 5g 1g 5g 5g 5g 1g 10g 5g 5g
5g 25g 5g 25g 25g 25g 5g 25g 5g 25g 25g 25g
References 1) Aldol reactions in aqueous media S. Kobayashi, . 1991, 2187; S. Kobayashi, I. Hachiya, . 1992, , 1625. 2) Reusable catalysts for Michael and Diels-Alder reactions S. Kobayashi, I. Hachiya, T. Takahori, M. Araki, H. Ishitani, . 1992, , 6815. 1994, 689; S. Kobayashi, I. Hachiya, 3) Reviews: S. Kobayashi, 1995, , 370; T. Ogino, T. Onozawa, 2000, number Ishikawa, , 2; S. Kobayashi, T. Hamada, S. Nagayama, K. Manabe, , 627; S. Kobayashi, . 2007, , 235.
, 1998,
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
, 71; K. . 2001,
23
Polymer-Supported Reagents
Polymer-Supported Reagents In recent years, the trend in synthetic organic chemistry has been to put special emphasis on harmonization with the environment and reaction efficiency. Much R&D is taking place to address these issues. Polymer-supported synthetic reagents and catalysts are drawing much attention due to the ease of recovery of the reagent after reaction. For this reason, many polymer-supported reagents and catalysts with excellent properties have been reported. One of the most common hypervalent iodine compounds, diacetoxyiodobenzene, has been supported on polystyrene by Togo and co-workers, and they have reported the oxidation of various functional groups. For example, they have reported the oxidation of alcohols in the presence of this polymer-supported reagent and TEMPO.1) Ishikawa and co-workers have developed 1,3-dimethylimidazolidinone supported on polystyrene. The derived 2-chloro-1,3-dimethylimidazolidium, using oxalyl chloride, is used for the esterification as a polymer-supported dehydrating and condensation reagent.2) On the other hand, active research for development of the polymer-supported catalysts has also been carried out. Yao has developed a polyethylene glycol-bound Grubbs catalyst analog for olefin metathesis reactions.3) After the reaction, this catalyst was precipitated by the addition of diethyl ether as a poor solvent. It can be recovered and reused. Ishihara and his group have developed a polystyrene-bound 4-bis(triflyl)methyl2,3,5,6-tetrafluorobenzene and demonstrated its applications as a solid super Brønsted acid catalyst.4) This solid catalyst swells effectively in organic solvents, and shows excellent activity with various acid-catalyzed reactions. This catalyst has been used in esterification, Friedel-Crafts reaction, Michael addition, acetalization, Sakurai-Hosomi allylation and Mukaiyama aldol reaction. Its catalytic activity was superior even to that of Nafion, which is well known as a solid strong acid. After reaction, the solid catalyst was quantitatively recovered by simple filtration and reused. It was also packed in a syringe as a reaction column, and various acid-promoted reactions were performed to afford the desired products by passing a solution of reactants through the syringe. Ikegami and co-workers have developed the Pd complex catalyst, one of the most utilized catalyst in the organic synthesis, to support the polymer, and reported its usefulness.5) This catalyst is a solid-phase catalyst which consists of an amphiphilic copolymer ligands, chloride and palladium. It takes up substrates and reagents of both hydrophilic and hydrophobic nature in the vicinity of palladium to smoothly promote the reaction. It forms a networked supermolecular complex, which is insoluble in water and organic solvents, and is easily recovered from reaction system. Since palladium is firmly held by the phosphine group of copolymer ligand, it is not lost during the reaction or upon work up; therefore, the catalyst can be recovered and reused multiple times. Ikegami and co-workers have demonstrated the uses of this catalyst for a Suzuki-Miyaura coupling reaction in water, and a Heck reaction in organic solvent. This amphiphilic polymer-supported Pd complex catalyst possesses high catalytic efficiency, and can be used in either water or organic solvents. It is now attracting attention as it has fulfilled harmonization with the environment and reaction efficiency. A2006
B2372
B2370
B2371
CH2NHCH2CH2NH P
P
CH2O
C NH(CH2)4NHO2S
P
CH2O
C NH(CH2)2NHO2S
O 2N
B2292
C2141 F
CH2O
C NH(CH2)3NHO2S
D3525
O 2N
D2766
F CH
P F
SO2CF3 SO2CF3
CH3
CH2N C N P
CH2 N (CH2)3N C NCH2CH3
P
CH3
I0680
O CH2NH C
N
N N
M1452
CH2
O P
CH2
N
N
CH3
CH2 N P
OH
24
P
M1857
CH2NCO P
P
Cl
F
H1208
P
P
O 2N
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
O
Polymer-Supported Reagents
P1415
P1427 O
P1697
CH3
O
PEG O C (CH2)2 C O
O C CH3 P
P1425
O
O Ru
I
(CH2 CH)12 (CH2 CH)1
CH CH3 Cl Cl
C O CH3
CH3
P
CH3 2
20
n
O
S0545
NH
CH3 N CH3 C12H25 n
NH2
N
SO2Cl
(CH2)3
P
CH3 CH3 N CH3 n
C12H25 RuO4 n
P
N H
N NH2
Product No. Product Name A2006
N-(2-Aminoethyl)aminomethyl Polystyrene Resin cross-linked with 1% DVB (50-100mesh)
B2372
N-(4-Benzyloxytrityl)-N '-(2-nitrobenzenesulfonyl)-1,4-diaminobutane Resin cross-linked with
B2370
N-(4-Benzyloxytrityl)-N '-(2-nitrobenzenesulfonyl)-1,2-diaminoethane Resin cross-linked with
(3.1-3.5mmol/g)
Unit Size 5g
1g
1% DVB (200-400mesh) (0.9-1.1mmol/g)
B2371
N-(4-Benzyloxytrityl)-N '-(2-nitrobenzenesulfonyl)-1,3-diaminopropane Resin cross-linked with
B2292 C2141
Bis(trifluoromethanesulfonyl)methyltetrafluorophenyl Polystyrene Resin N-Cyclohexylcarbodiimidomethyl Polystyrene Resin cross-linked with 1% DVB (50-100mesh)
D3525
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Resin cross-linked with 1% DVB (50-100mesh)
D2766 H1208
4-Diphenylphosphinomethyl Polystyrene Resin cross-linked with 2% DVB (200-400mesh) (0.5-1.0mmol/g) 1-Hydroxybenzotriazole-6-carboxamidomethyl Polystyrene Resin cross-linked with 1% DVB
I0680 M1452 M1857 P1415 P1427 P1425
Isocyanatomethyl Polystyrene Resin cross-linked with 1% DVB (50-100mesh) (2.0-2.5mmol/g) 3-Methyl-2-oxoimidazolidin-1-ylmethyl Polystyrene Resin cross-linked with 1% DVB Morpholinomethyl Polystyrene Resin cross-linked with 1% DVB (50-100mesh) (2.9-3.5mmol/g) Poly[4-(diacetoxyiodo)styrene] Polyethylene Glycol-bound Ruthenium Carbene Complex Poly[N-isopropylacrylamide-co-4-(diphenylphosphino)styrene] Palladium(II) Dichloride
P1697
Poly[[N-isopropylacrylamide-co-[N-[3-(dodecyldimethylammonio)propyl]acrylamide]]phosphotungstate] Poly[[N-isopropylacrylamide-co-[N-[3-(dodecyldimethylammonio)propyl]acrylamide]co-(1,3,5-triacryloylhexahydro-1,3,5-triazine)]perruthenate] Sulfonyl Chloride Polystyrene Resin cross-linked with 1% DVB (50-100mesh) (4.5-4.8mmol/g) Tris(2-aminoethyl)amine Polystyrene Resin cross-linked with 1% DVB (50-100mesh)
1g 100mg
1% DVB (200-400mesh) (0.9-1.1mmol/g)
(1.4-1.6mmol/g) (1.0-1.3mmol/g)
(50-100mesh) (1.3-1.5mmol/g)
(ratio, acrylamide:phosphine=20:2)
S0545 T2715
(0.4-0.8mmol/g)
25g 1g
1% DVB (200-400mesh) (0.9-1.1mmol/g)
P1698
n/3
T2715
(CH2 CH)x (CH2 CH)y (CH2 CH)z C O C O C O CH CH3
(CH2)3
PW12O403
P1698
NH
NH
CH CH3
PdCl2
P
O C CH3
C O
NH
O
NH
5g
25g
5g
25g 5g
5g 5g
25g 25g 1g 5g 25g 1g 5g 100mg 100mg
1g
200mg
1g
200mg 5g
1g 25g
5g
25g
References 1) 2) 3) 4) 5)
2002, 1966; Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 2003 113131, 2003. H. Togo, K. Sakuratani, 2003, 115. W. Disadee, T. Watanabe, T. Ishikawa, Q. Yao, . 2000, , 3896. K. Ishihara, A. Hasegawa, H. Yamamoto, . 2001, , 4077. Y. M. A. Yamada, K. Takeda, H. Takahashi, S. Ikegami, . 2002, , 3371; Y. M. A. Yamada, K. Takeda, H. Takahashi, S. Ikegami, . 2003, , 2379; Y. M. A. Yamada, K. Takeda, H. Takahashi, S. Ikegami, . 2003, , 7733; Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 2003 236388, 2003.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25
Asymmetric Organocatalysts
Asymmetric Organocatalysts Eder . and Hajos . separately reported an intramolecular asymmetric aldol reaction which employed proline as the only asymmetric catalyst at the beginning of the 1970s.1) This reaction was considered to be a special case at that time. Later in 2000, List . reported an intermolecular asymmetric aldol reaction which used proline as a catalyst.2) List’ s report received broad attention and served as a trigger to make research active for asymmetric organic catalysts. Therefore, varieties of asymmetric organic catalysts have been developed and the research has been applied to many areas.3) The proline derivative 1, having the heterocyclic ring was developed by Nakamura . It shows high TON as an asymmetric catalyst for obtaining a chiral aldol adduct.4) O Br O Br
N H
N H
Br
C NH S
S 1 O O . CF3CO2H (0.5 mol%)
HO
O
Br
Acetone, H2O
N H
O
O
Y. 70%, 92% e.e.
Compared with conventional metal complex catalysts, asymmetric organic catalysts are considered to be environmentally friendly and are expected to be further developed because they are stable, easy to handle and free of harmful metals.
A1301
A0945
A1043 O
N
Prolines and its analogs
B3440
D3803
H3C
D3804
N H
H3C C Si O
N H
N H
NH
D3185
N H
D2735
N H
H0784
OH
H0768 OH
OH
C
N H
M1169
N
C
M1097
N CH2OCH3
C
CH3
M1161
N H
D3186
N H
C OH
D2365
N H
OH
CH2NH
O
H3C
26
CH2NH2
CH2CH3
N H
CH2OCH3
CH3
I0395 OH
N
C
CH3
OH
N H
M1183
O
M2077
CH3
CH2NH N CH3
CH2 N
N H
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
C OH O
Asymmetric Organocatalysts
M1995
O0370
P1830
P1404
P0994
H N
N H H
CH3
. 2HCl P0481
O
O
N
N H
C OH
P1241
O
C OH
P1784
N H
O
CH2 N
N H
N H
N H
N
O
O
C NH S
HO C S
Unit Size
(S)-(-)-2-Aminomethyl-1-ethylpyrrolidine (S)-(+)-2-(Anilinomethyl)pyrrolidine L-Azetidine-2-carboxylic Acid trans-4-(tert-Butyldiphenylsilyloxy)-L-proline (R)-(+)-2-(Diphenylmethyl)pyrrolidine (S)-(-)-2-(Diphenylmethyl)pyrrolidine (2R,5R)-2,5-Diphenylpyrrolidine (2S,5S)-2,5-Diphenylpyrrolidine (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol (R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine (S)-(+)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine (S)-(-)-Indoline-2-carboxylic Acid (R)-2-(Methoxymethyl)pyrrolidine (S)-2-(Methoxymethyl)pyrrolidine (S)-(-)-1-Methyl-2-(1-naphthylaminomethyl)pyrrolidine (S)-(-)-1-Methyl-2-(1-piperidinomethyl)pyrrolidine α-Methyl-L-proline (S)-2-[(1-Methyl-2-pyrrolidinyl)methyl]isoindoline Dihydrochloride (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic Acid D-Pipecolic Acid L-Pipecolic Acid D-Proline L-Proline (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine (S)-5-(Pyrrolidin-2-yl)-1H-tetrazole N-(2-Thiophenesulfonyl)-L-prolinamide Trifluoroacetate L-Thioproline
A0177
1g 1g 100mg 1g
1g 1g 1g 1g 5g 1g 5g 25g 1g 100mg 25g
Other Amino Acids
O
OH
OH NH2
O
OH NH2
O OH
OH NH2
CH3
T0541
O
CH3
O
(CH3)3CO OH
NH2
T0539 OH
O
CH3
CH3
NH2
T0230
5g 5g 1g 5g 1g 1g 100mg 100mg 5g 5g 5g 5g 5g 5g 5g 1g 5g 5g 5g 5g 25g 5g 25g 250g 5g 500mg 100mg 500g
B3398
O OH
1g 1g 1g 1g 1g 1g 1g
100mg
A0179
CH3
T0228
NH
S
O
. x CF3CO2H
Product No. Product Name A1301 A0945 A1043 B3440 D3803 D3804 D3185 D3186 D2365 D2735 H0784 H0768 I0395 M1169 M1161 M1097 M1183 M2077 M1995 O0370 P1830 P1404 P0994 P0481 P1241 P1784 T2637 T0219
O
T0219 O
N
N
OH
N H
C OH
T2637
OH
N H
N H
N H
NH2
OH N H
NH2
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
27
Asymmetric Organocatalysts
Product No. Product Name A0177 A0179 B3398 T0228 T0230 T0539 T0541
Unit Size
D-Alanine L-Alanine
5g 25g 1g 25g 25g 5g
O-tert-Butyl-L-threonine D-(+)-Threonine L-(-)-Threonine D-Tryptophan L-Tryptophan
B1683
B1689
CH2
CH
B1684 H
H
CH2
H
CH
H
N
N HO
CH2
Cinchona Alkaloids
C0347 CH2
CH
CH
Cl N
CH2
HO
H
CH2
H
CH3O
N
B1685
CH2
Cl
Cl HO
25g 250g 5g 500g 500g 25g 25g
C0348 CH2 CH
H
N
N
C0349
H
CH2 CH
H
C0350 CH2 CH
H
H CH2
CH
Cl H
HO
N
H
HO
N
HO
H
N
CH2
N
N
C0351
N
HO
H
H
Q0006
O
H
N HO
. H2SO4 . 2H2O
H
N
28
CH2
HO
H
CH3O
N
HO
H
CH
H
N-Benzylcinchonidinium Chloride N-Benzylcinchoninium Chloride N-Benzylquinidinium Chloride N-Benzylquininium Chloride Cinchonidine Cinchonidine Dihydrochloride Cinchonidine Sulfate Cinchonine Cinchonine Hydrochloride Hydrate Hydroquinidine Hydrochloride β-Isocupreidine Quincoridine Quincorine Quinidine
N
N
. HCl . 2H2O
CH3O
2
Product No. Product Name B1683 B1689 B1684 B1685 C0347 C0348 C0349 C0350 C0351 H0752 I0728 Q0076 Q0074 Q0006
H
CH
N
N
N
Q0030 CH2 CH
CH3O
CH3O
N
HOCH2
CH2OH
H CH2
H
Q0028
H
CH2 CH
N
Q0010 CH2 CH
Q0074 CH2 CH
HO
N
N
N
Q0076
N
. HCl
H
CH3CH2
H
N
CH3O
. HCl . xH2O
HO
HO
N
I0728 CH3CH2
N
N
. 2H2SO4 . 2H2O
N
H0752 H CH
HO
H
. 2HCl
CH3O
CH2
HO
N
Unit Size
25g 25g 25g 25g 100mg 100mg 5g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
10g 5g 5g 5g 250g 25g 500g 200g 25g 250g 1g 1g 1g 25g
Asymmetric Organocatalysts
Product No. Product Name Q0010 Q0028 Q0030
Unit Size
Quinidine Sulfate Dihydrate Quinine Quinine Hydrochloride Dihydrate
5g 25g
B1143
B1144
O
O
Chiral Phosphoric Acids
O
P OH
O
O
O P OH
Product No. Product Name B1143 B1144
25g 500g 25g
Unit Size
(R)-(-)-1,1'-Binaphthyl-2,2'-diyl Hydrogen Phosphate (S)-(+)-1,1'-Binaphthyl-2,2'-diyl Hydrogen Phosphate
100mg
B1142
B1100
Chiral Diols
1g 100mg
5g 1g
B2048
OH
OH
OH
OH
OH
HO
O
O
H3C CH3
B1614
B1615 OH
HO
O
O
OH
HO
O
O
H3C
H3C CH3
Product No. Product Name B1142 B1100 B2048 B1614 B1615
Unit Size
(R)-(+)-1,1'-Bi-2-naphthol (S)-(-)-1,1'-Bi-2-naphthol (+)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane (-)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane (+)-4,5-Bis[hydroxy(diphenyl)methyl]-2-methyl-2-phenyl-1,3-dioxolane B1683
5g 5g 1g
B1689
CH2
CH
B1684 H
H
CH2
H
CH
H
N
N HO
CH2
Chiral Phase-Transfer Catalysts
D3475 CH2
CH
H
N CH2
CH3O
Cl N
CH2
HO
H
CH2
H
N
N
D3476
H Cl
HO
CH
CH3O
N
B1685
CH2
Cl
Cl HO
25g 25g 5g 5g 1g
CH3 CH2Ph CH2 N CH2 O O CH2 N CH2 CH2Ph CH3
CH3 CH3 2BF4
2
2
CH3 CH2Ph CH2 N CH2 O O CH2 N CH2 CH2Ph CH3
CH3 CH3
2
2
2BF4
N
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
29
Asymmetric Organocatalysts
Product No. Product Name
Unit Size
N-Benzylcinchonidinium Chloride N-Benzylcinchoninium Chloride N-Benzylquinidinium Chloride N-Benzylquininium Chloride 6,10-Dibenzyl-N,N '-dimethyl-N,N,N ',N '-tetrakis(4-methylbenzyl)-1,4-dioxaspiro[4.5]decane(2R,3R)-diylbis(methylammonium) Tetrafluoroborate [=(R,R)-TaDiAS-2nd] 6,10-Dibenzyl-N,N '-dimethyl-N,N,N ',N '-tetrakis(4-methylbenzyl)-1,4-dioxaspiro[4.5]decane(2S,3S)-diylbis(methylammonium) Tetrafluoroborate [=(S,S)-TaDiAS-2nd]
B1683 B1689 B1684 B1685 D3475 D3476
B3296
B3549
10g 5g 5g 5g 200mg
1g
200mg
1g
D3983 CH3
N S
Other Catalysts
N
S
N
H
N N
CH3
N Cl
H
D3984
CH3
N
O
. H2O
T1215 CH3
H
H
CH3
N
N N O
CH3
N
N
S
. HCl
Cl
. H2O
Product No. Product Name B3296 B3549 D3983 D3984 T1215
(+)-Benzotetramisole (-)-Benzotetramisole (+)-(5aR,10bS)-5a,10b-Dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazinium Chloride Monohydrate (-)-(5aS,10bR)-5a,10b-Dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazinium Chloride Monohydrate Levamisole Hydrochloride
Unit Size 200mg
1g 1g 100mg
10g
100mg 25g
References 1) U. Eder, G. Sauer, R. Wiechert, . 1971, , 496; Z. G. Hajos, D. R. Parrish, , 1615. 2) B. List, R. A. Lerner, C. F. Barbas III, . 2000, , 2395. 3) Review: . 2004, , 487-631,“Asymmetric Organocatalysis”(special edition); H. Pellissier, 2007, , 9267; A. Berkessel, H. Gröger, in , Wiley-VCH, Weinheim, 2005. 4) S. Nakamura, N. Hara, H. Nakashima, K. Kubo, N. Shibata, T. Toru, . 2008, , 8079.
30
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
. 1974,
Asymmetric Synthesis
Asymmetric Synthesis In the research and development of pharmaceuticals, agricultural chemicals or functional materials starting with ferroelectrical liquid crystals, the demand for optically active compounds has increased more than ever. In order to obtain the desired optically active compounds through synthesis, diastereoselective and enantioselective reactions have employed chiral auxiliaries or asymmetric catalysts. In order to achieve even higher optical purity and yield, new chiral auxiliaries and asymmetric catalysts are being developed and a considerable number of successful results have been reported. For instance, camphorsultam and oxazolidinone derivatives are utilized as chiral auxiliaries. BINAP-Rh complexes and oxazaborolidine derivatives are excellent asymmetric catalysts. All of these new developments produce products of high optical purity and good reaction yields. Optically active cobalt(II) complex catalyst, MPAC, developed by Yamada and co-workers is one of these catalysts, and is utilized for a pro-chiral ketone and imine asymmetric reduction.1) Through this asymmetric reduction using MPAC, secondary alcohols and amines of high optical purity can be obtained in good yields. The reaction proceeds under relatively moderate temperatures and utilize sodium borohydride, which has been traditionally employed as a reducing agent of ketones and imines. For this reason, this method is receiving much attention as a route to useful optically active alcohols and amines.
A1534
A1535
A1138
CH3 SO2
CH3 Ph
N O
CH3 Ph
CH3
SO2
CH3
Ph
N O
CH3 Ph
O
CH3
A1548
O
O CH3
OH
A2316
A2317
NH2
NH SO2
O
A1337
OH NH2
NH2
NH2
OH
OH
NH O
CH3
NH2
A1699
NH2
CH2
A0179
O
O
A2095
H2N
CO Ph Ph P CH3 Fe C
CH3
CH3 CH3
A0177
CH3
A1335
NH SO2
CH3
A1301
A1521
A0945 OH
N
CH2OCH3
N
NH2
CH2OCH3
N
NH2
A1043
OH
CH2NH2
B3296
B3549
B1683
N OH
CH
N
S
H
H
CH2
CH
Cl
Cl
N
S
CH2NH
B1689
CH2
O
N H
NH2
CH2CH3
HO
N
H
N
N HO
CH2
CH2
H
NH N
B2103
B2104 CH3
P1371
CH3
SO2 N CH3
Bn
OH
CH3
SO2 CH3
N Bn
B1786 CH3 CH3
CH3
CH3 Ph
P1372 CH3
CH3 CH3
N
Ph
CH3
SO2 N CH3
Bn
CH3
Ph O
CH3
OH O
SO2 CH3
Bn
CH2
Ph
N O
NH CH3
O
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
O
O
31
Asymmetric Synthesis
B1754
B1528
B1529 H N
CH3
CH2
B2165 H N
CH3
O
O
B1685
B1142
H CH2
CH2
CH
CH
HO
N O
O
B1100
O
B2230
H
Cl N
C CH2CH3
CH2
N
O
B1684
O
C CH2CH3
CH2
NH O
B2166
O Cl
CH2
HO
H
H
N
OH
OH
CH2
OH
OH
CH3O
CH3O
O S CF3 O O O S CF3 O
N
N
B2231
B1143
B1144
B2314
B2315
CH3
O O S CF3 O O O S CF3 O
B2090
O
O
P OH
O
O
CH3
N
CH3
N
O
O
CH3
O
N
B2653
CH3
N
CH3
O
CH3
O
CH3
CH3
B3449
CH3
B1406
PPh2 Rh
(CH3)3C
CH3
P
OH
(CH3)3C
P
N
N HO
C(CH3)3
(CH3)3C
C(CH3)3 (CH3)3C
PPh2
N
OH
HO
O
Co CH3
O
CH3
N
BF4
CH3
CH3 CH3
Co CH3
B2652
CH3
O
O
P OH
O
CH3
CH3 CH3
C(CH3)3
PPh2
PPh2
C(CH3)3 (CH3)3C
C(CH3)3
CH3
B1405
B2704
B1113
CH3
PPh2
H
P 2
PPh2
P
B1112
CH3 O CH3 O
CH3
H
2
B2048
CH2 P
CH3 O
CH2
P
CH2 P
CH3 O
CH2
P
OH
HO
O
O
H3C CH3
B1614
B1615 OH
B2409 OH
HO
B2217 O
HO N
CH3
N
C O
O
Mn
O
O
O
O Ph
O
O Ph
CH3
B3036 OCH3
B2034
CH3
B2220
O CH3
Co O
O CH3
O
N N
N
N
CH3
O N
CH3
O
N N
CH3
CH3
CH3
CH3
CH3 Ph
Ph
CH3
CH3 N
N Co
CH3
D2520
O
CH3
B1844
. HCl
CH3 Ph
CH3
N H
. HCl
B2219
CH3
CH3
CH3
N H
CH3O
B1845
32
CH3
PCH2CH2P
CH3O
CH3
N N
B2035
OCH3
PCH2CH2P
N
O
N
H3C
B3035
Ph
O
N N
H3C CH3
CH3
B2218
O
CH3
O
O
CH3
O CH3
D2521
F3CO2SHN
F3CO2SHN
N
CH3 O
O CH3
NHSO2CF3
NHSO2CF3
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Asymmetric Synthesis
B2907
B2908
B3398
C1324
C1325 CH3
O (CH3)3C S NH2
(CH3)3C S NH2
CH3
C1327
CH3
NH S
S
O
C1614 CH3
CH3
C0347 CH2 CH
CH3
B Cl
O
S O O
CH3
HO
H
CH3
CH2 CH
N
H
HO
CH2
CH
CH CH3 CH2Ph CH2 N CH2 O
N
N
N
HO
H
. 2H2SO4 . 2H2O
D2240
D2810
O CH2 N CH2 CH2Ph CH3
CH3
OH
2
OH
O
CH3
O
O
O
OH
2
OH
OH
OH
OH
OH
2BF4
D2729
D2730
D2801
OH OH
Br
D2802
D2128
Br
Br
Br
Br
OH
OCH3
OCH3
OH
OCH3
OCH3
Br
Br
CH3 Bu
N Bu
Br
Br
D2129
T1195
T0003
D3444
OH CH3
O
O
O
N O
OH
D3715
OH CH3
CH3
N C CH(C6H5)2
N C CH(C6H5)2
N C CH(C6H5)2
OH O
OH O
T0621
O
O CH3 O
CH3 O
CH3
OH CH3
O
O CH3 O
OH
D2538
N CH2CH2C(CH3)3
CH3 O
CH3
N CH2CH2C(CH3)3
OH
D2535
CH3
N CH2CH2C(CH3)3
D3808
CH3
D2537
CH3
OH
OH CH3
CH3
NH2
CH3
CH3
OH O
N C CH(C6H5)2
N CH2CH2C(CH3)3
O O
H2N
H2N
T1387
OH O
D3809
O
OH
D3716
O
OH
D3445 NH2
CH3
Bu
2
2BF4
Br
Br
Bu
2
D2811 Br
CH3 CH2Ph CH2 N CH2 O
CH3
N
N
D2239
CH3
O CH2 N CH2 CH2Ph CH3
H
. HCl . xH2O
N
D3476
D3475 H
H CH2
. 2HCl
N
2
C0351
H
HO
N
N
CH3
2
C0350
H
H
CH3
C0349 CH2 CH
HO
B Cl
O S O O
C0348
H
CH3
N
N
O
O
O
C2023 C1615
CH3
CH3
HN
OH NH2
C1326
CH3
CH3
O
(CH3)3CO
O
N(CH3)2 PPh2
CH3
(CH3)2N Ph2P
Fe
N(CH3)2 PPh2 Fe
PPh2
D2536
CH3
CH3 (CH3)2N Ph2P
Fe
Fe
Ph2P
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
33
Asymmetric Synthesis
D2176
D2175
D2130
NH2
D2131
D3803
NH2 N H
NH2
NH2
O
N
O
N
B
B
CH3
D3804
D3822
D2774 CH
N N H
D2775
D3185
CH3 CH3
OCH3
Fe PPh2 O
D3186
CH3
OCH3 P(C6H5)2
P(C6H5)2
D2365
D2735
D2702
N H
D2686 O
OH N H
N H
OH
C
N H
O
(CH3)3C
C
O
O
(CH3)3C
HO
OH O
O
OH O
C(CH3)3
O
O
HO
O
O
H0784
H0768
H0862
OH N
H0863
OH
C
N
CH3
HO CH3 O
O
CH3
I0728
I0480
CH3
CH3
CH3
CH3
I0476
CH3CH2 N
OH
HO
CH3
CH3 CH
HN
CH
CH3
O
I0762 CH3
CH3 H
OH
N H
I0761
CH3 O
I0395
HO CH3
C
C(CH3)3
O
CH2OH
NH O
NHCH(CH3)2
CH3 CH
NH
O
O
O
CH3 N
I0567
D2823
I0582 CH3
CH3 O
C
N
CH3
O
O
O
O
N
N
N
O
CH3
CH3 CH3
N
CH3
N O
CH3
NH S
O
M1066
CH3 O
O
T1215 N
CH3 COOH
N
S
. HCl
S
M1070
NH O
O
K0028 CH3
O
CH3
O
M1044
I0575
CH3
NH O
O
O
CH3
CH3
N
C(CH3)3
I0573
CH3
I0451
CH3
CH3
I0594
M0803
M1169
CH3
CH3 O
O
O S
O S
CH3 HO
CH3
CH3 CH3
34
C
N
C(CH3)3
CH3
I0572 CH3
CH3
C
CH3
CH3 CH2SH
CH3OCH2
N O
CH3
N H
CH2OCH3
CH3
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Asymmetric Synthesis
M1161
M1170
M1162
M1401
M1402 O
CH2OCH3
N N H
CH2OCH3
M1097
C H
C H
O
O
M1183
N
N
N
CH2 N
CH3
NH2
OH
OH
P1294
NH2
N
T1491
CH3
P1201 CH3
O N
N
. 2HCl
P0793
O
N
T1490
CH3
P0794
N
M1995
CH2NH
CH3
O
CH2OCH3
N
P1307
NH2
NH2 OH
OH NH O
P1308
P1374
P1375
P1830
N
P1404
N
O
NH CH3 O
N H
CH3
O
OH
P0994
O
C OH
P1241
P1784
Q0076
OH
N H
O
Q0074
N H
O
Q0006
CH2 N
H
HO
OO
Rh
O
R
O
O
Rh
O O O
Rh N
R=
R
O O
H
H
R
O
. 2 CH3
R'
Rh
R
H R'
Rh Rh O O O H R
O
R
O
O F
R=
R'=
N
R=
CH2
F O
. 2 CH3
O
F
C OCH2CH3
O O O
R H
R
O
H R
O
. CH3
O
O C OCH2CH3
F
N F
. 2 CH3
O
O
F
C OCH2CH3
R
O
H R
O
O
Cl O
. 2 CH3
O
Cl
H OO
O O O
R H
R
C OCH2CH3
R
O
R=
N
O
Rh Rh
N
R=
O H
Cl Cl
T0219
Cl Cl Cl
O H
. 2 CH3
O
O
Cl
C OCH2CH3
N H
T0228
O
O
C NH S
HO C
F
O H
. 2 CH3
C OCH2CH3
O R R=
O O O
R
H OO
Rh Rh
N
O H
F
O H
R
H OO
Rh Rh
R
O
O N
R=
O
H
R
O
O
H
H OO
R O
T2659 H
R O
T2637
R O
Rh
N
H R' OO
O
H
OO
Rh O O O
R
. HCl . 2H2O
CH3O
H
O
R
T2661 H
N
2
N
O O O
C OCH2CH3
T2660
R
. H2SO4 . 2H2O
H
H
HO
T2658 R' H
H
O
R
R
T1551 R H
H H
CH3O
N
N
T2054 CH
CH2
N
N
CH3O
HOCH2
CH
CH2OH
T2055
N H
H CH2
HO
N
Q0030
H
CH2 CH
N
N H
Q0010 CH2 CH
CH2 CH
N
N N H
C OH
N H
OH
P0481
OH
O
O
. x CF3CO2H
OH NH
S S
O
CH3
OH NH2
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
35
Asymmetric Synthesis
T0230
T2545 OH
T1380 O
O
CH3
T1381 CH3
NH2
T2223 CH3
Ph
NH2
CH2O Si CH3
S
CH3
CH2
N N
OH
Fe
t
Bu
Ph
H NH SO2
i
iPr
Pr
NH2 CH3
T2578
T2579
CH3
T1499
T1482 OH
CH3
CH3
iPr
T0539 O
OH
OH CH3
S
CH3
CH3
T0541
V0077 O
NH2
NH2
X0049 CH3
CH3 OH
NH2
N H
OH
V0058
CH3
Product No. Product Name A1534 A1535 A1138 A0177 A0179 A2095 A1548 A1699 A2316 A2317 A1337 A1335 A1301 A1521 A0945 A1043 B3296 B3549 B1683 B1689 B2103 B2104 P1371 P1372 B1786 B1754 B1528 B1529 B2165 B2166 B1684 B1685 B1142 B1100 B2230 B2231 B1143 B1144 B2314 B2315
OH
CH3 OH
N H
36
S
CH3
CH3
OH NH2
N H
CH2NH CH3
Unit Size
Acetic Acid (1R,2S)-2-[N-Benzyl-N-(mesitylenesulfonyl)amino]-1-phenylpropyl Ester 1g Acetic Acid (1S,2R)-2-[N-Benzyl-N-(mesitylenesulfonyl)amino]-1-phenylpropyl Ester 1g 5 100mg (R)-(-)-Acetylcarbonyl(η -2,4-cyclopentadien-1-yl)(triphenylphosphine)iron 5g 25g D-Alanine 25g 250g L-Alanine (S)-4-(4-Aminobenzyl)-2-oxazolidinone 1g 5g (R,R)-N-(2-Amino-1,2-diphenylethyl)-p-toluenesulfonamide 1g (S,S)-N-(2-Amino-1,2-diphenylethyl)-p-toluenesulfonamide 1g (R)-(+)-2-Amino-2'-hydroxy-1,1'-binaphthyl 100mg (S)-(-)-2-Amino-2'-hydroxy-1,1'-binaphthyl 100mg (R)-(+)-1-Amino-2-(methoxymethyl)pyrrolidine 1g (S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine 1g 5g (S)-(-)-2-Aminomethyl-1-ethylpyrrolidine 1g 5g (1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol Price on request (S)-(+)-2-(Anilinomethyl)pyrrolidine 1g 5g 100mg 1g L-Azetidine-2-carboxylic Acid (+)-Benzotetramisole 200mg 1g (-)-Benzotetramisole 1g N-Benzylcinchonidinium Chloride 10g N-Benzylcinchoninium Chloride 5g (1R,2S)-2-[N-Benzyl-N-(mesitylenesulfonyl)amino]-1-phenyl-1-propanol 1g 5g (1S,2R)-2-[N-Benzyl-N-(mesitylenesulfonyl)amino]-1-phenyl-1-propanol 1g 5g (1R,2S)-2-[N-Benzyl-N-(mesitylenesulfonyl)amino]-1-phenylpropyl Propionate 1g (1S,2R)-2-[N-Benzyl-N-(mesitylenesulfonyl)amino]-1-phenylpropyl Propionate 1g (R)-4-Benzyl-2-oxazolidinone 5g 25g (S)-4-Benzyl-2-oxazolidinone 5g 25g (R)-(+)-N-Benzyl-1-phenylethylamine 5ml 25ml (S)-(-)-N-Benzyl-1-phenylethylamine 5ml 25ml (R)-(-)-4-Benzyl-3-propionyl-2-oxazolidinone 1g 5g 25g (S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone 1g 5g N-Benzylquinidinium Chloride 5g N-Benzylquininium Chloride 5g (R)-(+)-1,1'-Bi-2-naphthol 5g 25g (S)-(-)-1,1'-Bi-2-naphthol 5g 25g (R)-(-)-1,1'-Binaphthyl-2,2'-diyl Bis(trifluoromethanesulfonate) 1g 5g (S)-(+)-1,1'-Binaphthyl-2,2'-diyl Bis(trifluoromethanesulfonate) 1g 5g (R)-(-)-1,1'-Binaphthyl-2,2'-diyl Hydrogen Phosphate 100mg 1g 5g (S)-(+)-1,1'-Binaphthyl-2,2'-diyl Hydrogen Phosphate 100mg 1g (1R,2R)-N,N '-Bis(2-acetyl-3-oxo-2-butenylidene)-1,2-dimesitylethylenediaminato Cobalt(II) 100mg (1S,2S)-N,N '-Bis(2-acetyl-3-oxo-2-butenylidene)-1,2-dimesitylethylenediaminato Cobalt(II) 100mg
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Asymmetric Synthesis
Product No. Product Name B2090 B2652 B2653 B3449 B1406 B1405 B2704 B1113 B1112 B2048 B1614 B1615 B2409 B2217 B2218 B3035 B3036 B2034 B2035 B1844 B1845 B2219 B2220 D2520 D2521 B2907 B2908 B3398 C1324 C1325 C1326 C1327 C1614 C2023 C1615 C0347 C0348 C0349 C0350 C0351 D3475
(S,S)-1,2-Bis[(tert-butyl)methylphosphino]ethane[η-(2,5-norbornadiene)]rhodium(I) Tetrafluoroborate (1R,2R,4R,5R)-2,5-Bis(3,5-di-tert-butyl-2-hydroxybenzylideneamino)bicyclo[2.2.1]heptane (1S,2S,4S,5S)-2,5-Bis(3,5-di-tert-butyl-2-hydroxybenzylideneamino)bicyclo[2.2.1]heptane (2R,3R)-(-)-2,3-Bis(diphenylphosphino)bicyclo[2.2.1]hept-5-ene (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (2S,3S)-(-)-Bis(diphenylphosphino)butane (2R,3R)-(-)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol (2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol (+)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane (-)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane (+)-4,5-Bis[hydroxy(diphenyl)methyl]-2-methyl-2-phenyl-1,3-dioxolane (1S,2S)-N,N '-Bis[(R)-2-hydroxy-2'-phenyl-1,1'-binaphthyl-3-ylmethylene]1,2-diphenylethylenediaminato Manganese(III) Acetate (R,R)-2,6-Bis(4-isopropyl-2-oxazolin-2-yl)pyridine (S,S)-2,6-Bis(4-isopropyl-2-oxazolin-2-yl)pyridine (R,R)-1,2-Bis[(2-methoxyphenyl)phenylphosphino]ethane (S,S)-1,2-Bis[(2-methoxyphenyl)phenylphosphino]ethane (R,R)-(+)-Bis(α-methylbenzyl)amine Hydrochloride (S,S)-(-)-Bis(α-methylbenzyl)amine Hydrochloride (1R,2R)-N,N '-Bis[3-oxo-2-(2,4,6-trimethylbenzoyl)butylidene]1,2-diphenylethylenediaminato Cobalt(II) (1S,2S)-N,N '-Bis[3-oxo-2-(2,4,6-trimethylbenzoyl)butylidene]1,2-diphenylethylenediaminato Cobalt(II) (R,R)-2,6-Bis(4-phenyl-2-oxazolin-2-yl)pyridine (S,S)-2,6-Bis(4-phenyl-2-oxazolin-2-yl)pyridine (R,R)-N,N '-Bis(trifluoromethanesulfonyl)-1,2-diphenylethylenediamine (S,S)-N,N '-Bis(trifluoromethanesulfonyl)-1,2-diphenylethylenediamine (R)-(+)-tert-Butylsulfinamide (S)-(-)-tert-Butylsulfinamide O-tert-Butyl-L-threonine (+)-10,2-Camphorsultam (-)-10,2-Camphorsultam (2R,8aS)-(+)-(Camphorylsulfonyl)oxaziridine (2S,8aR)-(-)-(Camphorylsulfonyl)oxaziridine (+)-B-Chlorodiisopinocampheylborane (58% in Hexane, ca. 1.6mol/L) (-)-B-Chlorodiisopinocampheylborane (60% in Heptane, ca. 1.7mol/L) (-)-B-Chlorodiisopinocampheylborane (60% in Hexane, ca. 1.7mol/L) Cinchonidine Cinchonidine Dihydrochloride Cinchonidine Sulfate Cinchonine Cinchonine Hydrochloride Hydrate 6,10-Dibenzyl-N,N '-dimethyl-N,N,N ',N '-tetrakis(4-methylbenzyl)1,4-dioxaspiro[4.5]decane-(2R,3R)-diylbis(methylammonium) Tetrafluoroborate [=(R,R)-TaDiAS-2nd]
D3476
6,10-Dibenzyl-N,N '-dimethyl-N,N,N ',N '-tetrakis(4-methylbenzyl)1,4-dioxaspiro[4.5]decane-(2S,3S)-diylbis(methylammonium) Tetrafluoroborate
D2239 D2240 D2810 D2811 D2729 D2730 D2801 D2802 D2128 D2129 T1195 T0003 D3444 D3445 D3715 D3716 T1387 T0621
(+)-1,4-Di-O-benzyl-D-threitol (-)-1,4-Di-O-benzyl-L-threitol (R)-3,3'-Dibromo-1,1'-bi-2-naphthol (S)-3,3'-Dibromo-1,1'-bi-2-naphthol (R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol (contains 5% Dichloromethane at maximum) (S)-(+)-6,6'-Dibromo-1,1'-bi-2-naphthol (R)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl (S)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl (1R,2S)-2-(Dibutylamino)-1-phenyl-1-propanol (1S,2R)-2-(Dibutylamino)-1-phenyl-1-propanol Diethyl D-(-)-Tartrate Diethyl L-(+)-Tartrate (11R,12R)-9,10-Dihydro-9,10-ethanoanthracene-11,12-diamine (11S,12S)-9,10-Dihydro-9,10-ethanoanthracene-11,12-diamine (1R,2R)-N,N '-Dihydroxy-N,N '-bis(diphenylacetyl)cyclohexane-1,2-diamine (1S,2S)-N,N '-Dihydroxy-N,N '-bis(diphenylacetyl)cyclohexane-1,2-diamine Diisopropyl D-(-)-Tartrate Diisopropyl L-(+)-Tartrate
[=(S,S)-TaDiAS-2nd]
Unit Size 50mg 100mg
1g 1g 100mg
1g
250mg
1g 500mg 100mg 100mg
100mg 100mg 5g 5g 1g 1g 1g 5g 5g 1g 100mg 5g 5g 1g 1g 5g 5g 100mg
250mg
1g 1g 1g 1g 1g
25g 25g 25g
100mg 1g 250mg 1g 1g 1g 1g 5g 5g 5g 5g 5g 100ml 100ml 100ml 250g 25g 500g 200g 25g
200mg
1g
200mg
1g 1g 1g 5g 1g 1g 5g 1g 1g 5g 5g 250g 500g 1g 1g 100mg 100mg 250g 500g
1g
1g 200mg 200mg 1g 1g 25g 25g 100mg 100mg
25g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
37
Asymmetric Synthesis
Product No. Product Name D3808 D3809 D2537 D2538 D2535 D2536 D2176 D2175 D2130 D2131 D3803 D3804 D3822 D2774 D2775 D3185 D3186 D2365 D2735 D2702 D2686 H0784 H0768 H0862 H0863 I0395 I0728 I0480 I0476 I0761 I0762 I0567 D2823 I0582 I0572 I0451 I0594 I0573 I0575 K0028 T1215 M1044 M1066 M1070 M0803 M1169 M1161 M1170 M1162 M1401 M1402 M1097 M1183 M1995 T1490 T1491 P0794 P0793 P1201 P1294 P1307 P1308 P1374 P1375 P1830 P1404 P0994 P0481
38
(1R,2R)-N,N '-Dimethyl-N,N '-bis(3,3-dimethylbutyl)cyclohexane-1,2-diamine (1S,2S)-N,N '-Dimethyl-N,N '-bis(3,3-dimethylbutyl)cyclohexane-1,2-diamine (R)-N,N-Dimethyl-1-[(S)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine (S)-N,N-Dimethyl-1-[(R)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine (R)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine (S)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine (1R,2R)-(+)-1,2-Diphenylethylenediamine (1S,2S)-(-)-1,2-Diphenylethylenediamine (R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine (S)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine (R)-(+)-2-(Diphenylmethyl)pyrrolidine (S)-(-)-2-(Diphenylmethyl)pyrrolidine (S)-1-(Diphenylphosphino)-2-[(S)-4-isopropyloxazolin-2-yl]ferrocene (R)-(+)-2-Diphenylphosphino-2'-methoxy-1,1'-binaphthyl (S)-(-)-2-Diphenylphosphino-2'-methoxy-1,1'-binaphthyl (2R,5R)-2,5-Diphenylpyrrolidine (2S,5S)-2,5-Diphenylpyrrolidine (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol (+)-Dipivaloyl-D-tartaric Acid (-)-Dipivaloyl-L-tartaric Acid (R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine (S)-(+)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine (1R,2R,5R)-(+)-2-Hydroxy-3-pinanone (1S,2S,5S)-(-)-2-Hydroxy-3-pinanone (S)-(-)-Indoline-2-carboxylic Acid β-Isocupreidine (S)-2-Isopropylamino-3-methyl-1-butanol (R)-2-Isopropylamino-2-phenylethanol (4R)-(+)-4-Isopropyl-5,5-diphenyl-2-oxazolidinone (4S)-(-)-4-Isopropyl-5,5-diphenyl-2-oxazolidinone (S,S)-(-)-2,2'-Isopropylidenebis(4-tert-butyl-2-oxazoline) (R,R)-2,2'-Isopropylidenebis(4-phenyl-2-oxazoline) (S,S)-2,2'-Isopropylidenebis(4-phenyl-2-oxazoline) (R)-4-Isopropyl-2-oxazolidinone (S)-4-Isopropyl-2-oxazolidinone (R)-(-)-4-Isopropyl-3-propionyl-2-oxazolidinone (S)-(+)-4-Isopropyl-3-propionyl-2-oxazolidinone (S)-4-Isopropylthiazolidine-2-thione (S)-(+)-Ketopinic Acid Levamisole Hydrochloride (1R,2S,5R)-(-)-Menthyl (S)-p-Toluenesulfinate (1S,2R,5S)-(+)-Menthyl (R)-p-Toluenesulfinate (1S)-(-)-10-Mercaptoisoborneol (4S,5S)-(-)-4-Methoxymethyl-2-methyl-5-phenyl-2-oxazoline (R)-2-(Methoxymethyl)pyrrolidine (S)-2-(Methoxymethyl)pyrrolidine (R)-(+)-2-(Methoxymethyl)-1-pyrrolidinecarboxaldehyde (S)-(-)-2-(Methoxymethyl)-1-pyrrolidinecarboxaldehyde (+)-2,2'-Methylenebis[(3aR,8aS)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole] (-)-2,2'-Methylenebis[(3aS,8aR)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole] (S)-(-)-1-Methyl-2-(1-naphthylaminomethyl)pyrrolidine (S)-(-)-1-Methyl-2-(1-piperidinomethyl)pyrrolidine (S)-2-[(1-Methyl-2-pyrrolidinyl)methyl]isoindoline Dihydrochloride (1R,2S)-(-)-trans-2-Phenyl-1-cyclohexanol (1S,2R)-(+)-trans-2-Phenyl-1-cyclohexanol (R)-(+)-1-Phenylethylamine (S)-(-)-1-Phenylethylamine (R)-(-)-2-Phenylglycinol (S)-(+)-2-Phenylglycinol (R)-(-)-4-Phenyl-2-oxazolidinone (S)-(+)-4-Phenyl-2-oxazolidinone (1R,2S)-1-Phenyl-2-(1-pyrrolidinyl)propan-1-ol (1S,2R)-1-Phenyl-2-(1-pyrrolidinyl)propan-1-ol D-Pipecolic Acid L-Pipecolic Acid D-Proline L-Proline
Unit Size
1g 1g 1g 1g
200mg 100mg 100mg
100mg
1g 1g 1g 5g 1g 1g 1g 1g 1g
5g 1g 1g 100mg 250mg 1g 250mg 1g 5g 1g 5g 1g 1g 1g 10g 5g 1g
1g 1g 1g 500mg 500mg 1g 1g 100mg 100mg 25ml 25ml 5g 5g 5g 5g 1g 1g 5g 1g 5g 25g
1g 1g 100mg 100mg 100mg 100mg 5g 5g 5g 5g 1g 1g 1g 1g 1g 100mg 100mg 5g 5g 5g 25g 5g 5g 5g 5g 5g 1g 5g 25g 5g 5g 1g 5g 1g 25g 25g 5g 5g 1g 5g 25g 25g 5g 1g 1g 5g 5g 1g 5g 1g 1g 1g 5g 5g 1g 1g 500ml 500ml 25g 25g 25g 25g 5g 5g 25g 5g 25g 250g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Asymmetric Synthesis
Product No. Product Name P1241 P1784 Q0076 Q0074 Q0006 Q0010 Q0030 T2054 T2055 T1551 T2658 T2659 T2660 T2661 T2637 T0219 T0228 T0230 T2545 T1380 T1381 T2223 T2578 T2579 T1499 T1482 T0539 T0541 V0077 V0058 X0049
(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine (S)-5-(Pyrrolidin-2-yl)-1H-tetrazole Quincoridine Quincorine Quinidine Quinidine Sulfate Dihydrate Quinine Hydrochloride Dihydrate Tetrakis[N-phthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-phthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-phthaloyl-(S)-phenylalaninato]dirhodium Ethyl Acetate Adduct Tetrakis[N-tetrachlorophthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrachlorophthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrafluorophthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrafluorophthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct N-(2-Thiophenesulfonyl)-L-prolinamide Trifluoroacetate L-Thioproline D-(+)-Threonine L-(-)-Threonine (R)-(p-Toluenesulfinyl)ferrocene (R)-(+)-1-(p-Tolyl)ethylamine (S)-(-)-1-(p-Tolyl)ethylamine Nα-(2,4,6-Triisopropylbenzenesulfonyl)-O-(tert-butyldiphenylsilyl)-π-methyl-L-histidinol (1R,4R,5R)-4,7,7-Trimethyl-6-thiabicyclo[3.2.1]octane (1S,4S,5S)-4,7,7-Trimethyl-6-thiabicyclo[3.2.1]octane (R)-(+)-1,1,2-Triphenyl-1,2-ethanediol (S)-(-)-1,1,2-Triphenyl-1,2-ethanediol D-Tryptophan L-Tryptophan D-Valinol L-Valinol (S)-(+)-2-(2,6-Xylidinomethyl)pyrrolidine
Unit Size 1g 5g 100mg 500mg 100mg 1g 100mg 1g 5g 25g 5g 25g 25g 100mg 100mg 100mg 50mg 100mg 50mg 100mg 100mg 25g 500g 25g 500g 25g 500g 1g 5g 1ml 5ml 1ml 5ml 100mg 1g 5g 1g 5g 1g 5g 1g 5g 25g 25g 1g 5g 5g 25g 1g 5g
References 1) T. Yamada, T. Nagata, Y. Ohtsuka, T. Ikeno, T. Mukaiyama, 2003, , 843; T. Yamada, T. Nagata, K. D. Sugi, K. Yorozu, T. Ikeno, Y. Ohtsuka, D. Miyazaki, T. Mukaiyama, 2003, , 4485.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
39
Chiral Building Blocks
Chiral Building Blocks
A1299
A1334 O
O CH3
Carboxylic Acids
A1450
OH
OH
CH3
CH3 NH2
A1043
B1121 O
B1757
B3177
N
OH Br
N
O
O
OH
C2109
NH2
CH3
O
Cl
OH Cl
C1954
D2636
O
O
C OH
C OH
O CH3
O
O
HO
CH3
D0083
CH3
OH CH3
OH O HO
OH Cl
O OH
O
CH3
. HCl
C1655
O
CH3
C1953
HO
O OH
Cl
Cl
O
D1386
OH Br
C1371 CH3
O
CH3
Cl
C
O
C OH
C OC(CH3)3
C1200
OH
O CH3
C1612
Cl
C1373
NH
C OC(CH3)3
CH3 OH
CH3
O
C1372
O
Cl
B1756
O
C OH
C1365
CH3
NH2
C OH
O
C1377
NH2
F
O CH3
C OH
O
B3178
F
O
C OH
O
NH C
NH
O
C OH OH
OH OH
Cl CH3
B1120 O
O H2N
S
OH
NH2
A1438
CH3
A1689
O OH
NH2
OH
A1688
O
. HBr
O
O
O S CH3
A0826
O
CH3
CH3
O
A1377
Br
O
A1620
C OH
C OH
O
O
D1573
OH O
CH3
O O
D1377
D3490
O CH3
O
O
HO
O OH
O
O
CH3
H2N
O OH
NH2
. 2HCl
H2N
OH NH2
O
O
. HCl
H2N
OH NH2
. HCl
HOOC
O C
OCH3
HOOC
O C
OCH3
O
O
40
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Chiral Building Blocks
D3491
D1398 D3826
D1354 D3492
O
O
O HOOC
O C
OCH3
HOOC
O C
OCH3
D2539
O
Ph
O
HO
OH . H2O O
O
HO O
D1417
O
(CH3)3C
HO O
HN
O
L0026
O O N
OH NH2
L0144
I0395
O
CH3
HO
NH
O
OH
NH2
C Cl
p-Tol
O
H0933
HO
O OH
O
H C O OH
O
H0758
O
HO
p-Tol
O
O
O
H0937
O
O
O O
HO
OH
O
G0265
p-Tol
O
HO
C(CH3)3
O
O
F0721 O
O
p-Tol
O OH
O
C(CH3)3
O
O
HO
OH
O
D1387 O
O O
Ph
O
C OH
NH2
O
D2686 O
OH
OH . H2O
Ph
O
CH3
O
O
(CH3)3C
CH3
O Ph
O
D2702
D3677
O
M0021
OH
N H
OH
O
OH
M0022
M0662 O
O CH3
CH3
OH CH3
O
O
OH
HO
OLi
M0661
M1366
OH
M1021 CH3
C OH
OH
M0830
M0829 O
CH3
C OH
M1229
HO
M1226 O
O OH
N0654
M1227
O
HO
HO
N0678 O
C OH
C OH
HO
O OH
O
CH3
O0370
O
CH3O
O0281
OH O
CH3
H
N H H
N H
P1288
O
O
C OH
P1168
O
O
C OH
P1219
O
O
NH2
OH
OH
OH NH2
CH3
C OH
P0936 O
O
O
O
CH3
O0276
O
P0820
C OH
O OH
O
CH3
N H
CH3O
C1461
O OH
CH3
O
C OH
O
CH3O
O
CH3O OH
CH3O
M1228
C OH
OH O
O
O HO
HO
OH O
OH
HO
O
C OH
O HO
OH O
OH
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
41
Chiral Building Blocks
P1830
P1404
Q0009
T0026
T0025
O HO C OH O N H
O
C OH
N H
OH
C OH HO
OH O
OH
OH
O
HO
O
HO
OH
OH O
OH
OH
T1740
T1741
T1515
T0219 O
O O O
O
C OH
O
C OH
C OH
T1900 O
HO C
NH
CF3
NH
OH
HO CH3
S
T1901 O CF3
OH
HO CH3
Product No. Product Name A1299 A1334 A1620 A1450 A1377 A0826 A1688 A1689 A1438 A1043 B1121 B1120 B1756 B1757 B3177 B3178 C1612 C2109 C1377 C1365 C1372 C1371 C1655 C1373 C1200 C1953 C1954 D2636 D1386 D0083 D1573 D1377 D3490 D3491 D1398 D3826 D1354 D3492 D2539 D3677
42
(S)-(-)-2-Acetoxypropionic Acid (S)-(-)-3-(Acetylthio)isobutyric Acid (R)-3-(Acetylthio)isobutyryl Chloride (S)-(+)-2-Amino-4-bromobutyric Acid Hydrobromide (R)-(-)-2-Aminobutyric Acid (S)-(+)-2-Aminobutyric Acid (1R,2R)-2-Aminocyclohexanecarboxylic Acid (1S,2S)-2-Aminocyclohexanecarboxylic Acid (S)-(-)-4-Amino-2-hydroxybutyric Acid L-Azetidine-2-carboxylic Acid [Antagonist of L-Proline] (+)-cis-2-Benzamidocyclohexanecarboxylic Acid (-)-cis-2-Benzamidocyclohexanecarboxylic Acid (R)-(+)-2-Bromopropionic Acid (S)-(-)-2-Bromopropionic Acid (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid (2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid 3-Chloro-L-alanine Hydrochloride (R)-2-Chlorobutyric Acid (S)-2-Chlorobutyric Acid (S)-2-Chloro-3-methylbutyric Acid (2S,3S)-2-Chloro-3-methylvaleric Acid (S)-2-Chloro-4-methylvaleric Acid (R)-(+)-2-Chloropropionic Acid (S)-(-)-2-Chloropropionic Acid D-(-)-Citramalic Acid (1R,2R)-1,2-Cyclohexanedicarboxylic Acid (1S,2S)-1,2-Cyclohexanedicarboxylic Acid (+)-Diacetyl-D-tartaric Acid (-)-Diacetyl-L-tartaric Acid (S)-(+)-2,4-Diaminobutyric Acid Dihydrochloride (R)-(-)-2,3-Diaminopropionic Acid Hydrochloride (S)-(+)-2,3-Diaminopropionic Acid Hydrochloride (+)-Di-p-anisoyl-D-tartaric Acid (-)-Di-p-anisoyl-L-tartaric Acid (+)-Dibenzoyl-D-tartaric Acid Monohydrate (+)-Dibenzoyl-D-tartaric Acid (-)-Dibenzoyl-L-tartaric Acid Monohydrate (-)-Dibenzoyl-L-tartaric Acid D-(-)-2-(2,5-Dihydrophenyl)glycine (S)-(+)-2,2-Dimethylcyclopropanecarboxylic Acid
Unit Size 1g
5g
1g 1g 1g
5g 100mg
5g 5g 200mg 200mg 1g 1g 1g 1g 1g 1g 1g 5g 1g 5g
100mg 100mg
25g 25g 25g 25g 5g 1g
25g 25ml 25g 5g 5g 5g 100mg 100mg 25g 1g 5g 5g 25g 25g 1g 1g 5g 5g 5g 5g 5g 5g 25g 25g 1g 1g 1g 5g 25g 1g 1g 1g 25g 25g 500g 250g 500g 250g 25g 5g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Chiral Building Blocks
Product No. Product Name D2702 D2686 D1417 D1387 F0721 G0265 H0937 H0758 H0933 I0395 L0026 L0144 M0021 M0022 M0662 M0661 M1366 M1021 M0830 M0829 M1228 M1229 M1226 M1227 C1461 N0654 N0678 O0370 O0281 O0276 P0820 P1288 P1168 P1219 P0936 P1830 P1404 Q0009 T0026 T0025 T1740 T1741 T1515 T0219 T1900 T1901
Unit Size
(+)-Dipivaloyl-D-tartaric Acid (-)-Dipivaloyl-L-tartaric Acid (+)-Di-p-toluoyl-D-tartaric Acid (-)-Di-p-toluoyl-L-tartaric Acid O-Formyl-D-mandeloyl Chloride (S)-(-)-2-Guanidinoglutaric Acid (R)-(+)-2-(4-Hydroxyphenoxy)propionic Acid D-(-)-2-(4-Hydroxyphenyl)glycine (S)-(+)-2-Hydroxy-4-phthalimidobutyric Acid (S)-(-)-Indoline-2-carboxylic Acid L-Leucic Acid Lithium L-Lactate D-(+)-Malic Acid L-(-)-Malic Acid D-(-)-Mandelic Acid L-(+)-Mandelic Acid (R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid (R)-(-)-α-Methoxyphenylacetic Acid (S)-(+)-α-Methoxyphenylacetic Acid (R)-(-)-2-Methylglutaric Acid (S)-(+)-2-Methylglutaric Acid (R)-(+)-Methylsuccinic Acid (S)-(-)-Methylsuccinic Acid 1-Monomethyl (R)-(+)-3-Methylsuccinate (R)-(-)-Nipecotic Acid (S)-(+)-Nipecotic Acid (2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic Acid (R)-(-)-5-Oxotetrahydrofuran-2-carboxylic Acid (S)-(+)-5-Oxotetrahydrofuran-2-carboxylic Acid D-2-Phenylglycine L-2-Phenylglycine (S)-(-)-3-Phenyllactic Acid (R)-(-)-2-Phenylpropionic Acid (S)-(+)-Phenylsuccinic Acid D-Pipecolic Acid L-Pipecolic Acid D-(-)-Quinic Acid D-(-)-Tartaric Acid L-(+)-Tartaric Acid (R)-(+)-Tetrahydrofuran-2-carboxylic Acid (S)-(-)-Tetrahydrofuran-2-carboxylic Acid (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid L-Thioproline (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid (S)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid
A2124
1g 5g 25g 25g
25g 1g 1g 5g 25g 25g 25g
5g 5g 1g 1g 1g 1g 1g 25g 25g 1g 1g 5g 1g
A1383 O
C CH3
O
O
O
C CH3 CH3
Esters
O
L0161
M1354 O
O
O
M1355
O
O
OH
O
O N
O OH
OCH3 CH3
T1671
CH3O C
O
S
O
B1755 O
O O
OH
25g 25g 5g 5g 5g 25g
1g
O
CH3
25g 1g 1g
100mg
A1101
O
5g 25g 250g 250g 25g 100mg 5g 500g 5g 5g 25g 25g 25g 500g 500g 250g 100mg 500g 5g 5g 5g 5g 25g 25g 1g 5g 5g 5g 5g 5g 500g 500g 5g 5g 1g 25g 5g 25g 500g 500g 25g 25g 25g 500g 1g 1g
O
CH3
C O C CH3 CH3 CH3
CH3
OH
O
O
O O
OH
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
43
Chiral Building Blocks
T0005
D3898
OH
OH
O
CH3(CH2)3O
O(CH2)3CH3 O
M1351
T1195
O
CH3
T1387
CH3
O O
OH
O
CH3
O O
OH
T0621
CH3
OH
O
O
O O
CH3
CH3
O
CH3
OH CH3
O
CH3 O
M1343
OCH3 O
CH3O
OCH3 O
OH
T1659 OH
OH OCH3
O
OH
O
O OH
C1634
CH3
O
O
O
CH3 CH3
OH
CH3
O
HO
O Br
O CH3
OCH3 CH3
OCH3 Cl
H0956 O
O OCH3
HO
CH3
CH3
HO
M1350
P0011 O
OCH3 OH
OCH3
OCH3 CH3
O
CH3
C1633
H0702
OCH3 OH
SO3 CH3
B2140
OCH3
CH3
O CH3
N H
M1349 O
OCH3
O
O
L0163
CH3
C OCH2CH3
O O O
L0136
O
H0703
OCH3
CH3
T1241
C OCH2CH3
CH3
D2562
Cl
44
O
CH3O C
CH3
OH
O
Br
O
OCH2CH3
N
O
CH3
O
CH3
OCH3 O
L0162
N0679
B2139
O
CH3
CH3CH2 O
N H
L0115
O
OCH3 O
CH3O
CH3
OH
H0904
OCH2CH3
N0655
CH3
OH
O
E0450
N
O O
CH3
OCH3
CH3CH2 O
M1273
O
M1232
O OCH3
O
CH3 CH3
O
CH3O
OH
M1344
CH3O
O
O
E0469
O
CH3O
CH3
CH3O
CH3
T0006
O
O
OH
C OCH3
O
O
M1231
O
O
O CH3O
CH3
O
C OCH3 CH3O C
CH3O C
CH3
M1230
O OH
O
O
CH3
M1347
O
O
I0447
OH
CH3 O
OH
O
CH3
O
I0474
CH3
O CH3 O
OH
O
CH3
OH
O OH
OH
O
O
OC(CH3)3 O
T0003
O
(CH3)3CO
OH
M1348
CH3 OCH3
OH
OH
CH3 O
O
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Chiral Building Blocks
P1189
R0063 O
O
CH3O C
C OCH3 O
HO O
O
O
CH3
OH
OH
Product No. Product Name A2124 A1101 A1383 L0161 M1354 M1355 B1755 T1671 T0005 D3898 M1351 M1348 T1195 T0003 T1387 T0621 I0474 I0447 M1347 M1343 M1230 M1231 M1232 T1659 T0006 E0469 E0450 L0162 M1344 M1273 N0655 N0679 T1241 H0904 L0115 B2139 B2140 C1633 C1634 D2562 H0703 H0702 H0956 L0136 L0163 M1349 M1350 P0011 P1189 R0063
(+)-O-Acetyl-D-malic Anhydride (-)-O-Acetyl-L-malic Anhydride (R)-(+)-3-(Acetylthio)isobutyric Acid Methyl Ester Benzyl (S)-(-)-Lactate Benzyl D-(-)-Mandelate Benzyl L-(+)-Mandelate (S)-(-)-3-tert-Butoxycarbonyl-4-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine Dibenzyl L-Tartrate Dibutyl L-(+)-Tartrate Di-tert-butyl L-(+)-Tartrate Diethyl D-(+)-Malate Diethyl L-(-)-Malate Diethyl D-(-)-Tartrate Diethyl L-(+)-Tartrate Diisopropyl D-(-)-Tartrate Diisopropyl L-(+)-Tartrate Dimethyl (+)-2,3-O-Isopropylidene-D-tartrate Dimethyl (-)-2,3-O-Isopropylidene-L-tartrate Dimethyl D-(+)-Malate Dimethyl L-(-)-Malate Dimethyl (S)-(+)-2-Methylglutarate Dimethyl (R)-(+)-Methylsuccinate Dimethyl (S)-(-)-Methylsuccinate Dimethyl D-(-)-Tartrate Dimethyl L-(+)-Tartrate Ethyl (R)-(+)-1-Ethyl-2-pyrrolidinecarboxylate Ethyl (S)-(-)-1-Ethyl-2-pyrrolidinecarboxylate Ethyl L-(-)-Lactate Ethyl D-(-)-Mandelate Ethyl L-(+)-Mandelate Ethyl (R)-(-)-Nipecotate Ethyl (S)-(+)-Nipecotate Ethyl L-(-)-O-Tosyllactate (R)-2-Hydroxy-4-phenylbutyric Acid Ethyl Ester L-(-)-Lactide Methyl (R)-(+)-3-Bromoisobutyrate Methyl (S)-(-)-3-Bromoisobutyrate Methyl (R)-(+)-2-Chloropropionate Methyl (S)-(-)-2-Chloropropionate Methyl (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxylate Methyl (R)-(-)-3-Hydroxyisobutyrate Methyl (S)-(+)-3-Hydroxyisobutyrate Methyl (R)-(+)-2-(4-Hydroxyphenoxy)propionate Methyl D-(+)-Lactate Methyl L-(-)-Lactate Methyl D-(-)-Mandelate Methyl L-(+)-Mandelate D-(-)-Pantolactone (2R,3R)-2,3-O-(1-Phenylethylidene)-L-tartaric Acid Dimethyl Ester D-(+)-Ribono-1,4-lactone
Unit Size 1g 5g
1g
5g 5g 5g 5g 25g 5g 5g 25g 25g 25g 25g 5g 5g 5g
5g 5g 1g 1g 25g 5g 5g 5g 5g 1g 25g 1g 1g
5g 5g 5g 5g 25g 1g 1g 25g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 25g 25ml 25g 25g 25g 25g 25g 500g 1g 25g 25g 250g 500g 250g 500g 5g 25g 25g 25g 5g 5g 25g 25g 25g 5g 5g 500g 25g 25g 25g 25g 25g 5g 250g 5g 5g 5g 5g 25g 25g 25g 25g 25g 500g 5g 5g 500g 5g 5g
45
Chiral Building Blocks
A1169
Amides
A1170
A1342
O NH C CH3
CH3
H NH2
N
. HCl
NH2
D3676
O
H
H H H
O O C CH3
NH
D1539
CH3 CH3
CH3
C NH C CH3 CH3
NH
CH3 C
Si
CH3 CH3
O
CH3
CH3
CO2H
OH
H N
CH2
O
O
OH
CH2
N H
NH
H
E0468
Si O H 3C CH3
O
B1776
NH2
CH2CH3
(CH3)3C
N H
B3410
O
CH3
O NH C CH3 N H
A2252
A1124
O
E0452
H1241
H0867
CH3 O
CH3 N C NH2
O
C NH2
N
CH2CH3
O
L0167
T1702 O
CH3
C NH2
HOCH2
CH2CH3
T1369 OH
H N
OH O
OH
O
HOCH2
O
O
NH C CF3
NH C CF3
. HCl
N H
N H
Unit Size
(3R)-(+)-3-Acetamidopyrrolidine (3S)-(-)-3-Acetamidopyrrolidine (3R,4R)-4-Acetoxy-3-[(R)-(tert-butyldimethylsilyloxy)ethyl]-2-azetidinone (S)-2-Aminobutyramide Hydrochloride (R)-(+)-2-Aminomethyl-1-ethylpyrrolidine (S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide (3S,4S)-3-[(R)-1-(tert-Butyldimethylsilyloxy)ethyl]-4-[(R)-1-carboxyethyl]-2-azetidinone (+)-N,N '-Diallyl-L-tartardiamide (S)-(+)-2,2-Dimethylcyclopropanecarboxamide (R)-(+)-1-Ethyl-2-pyrrolidinecarboxamide (S)-(-)-1-Ethyl-2-pyrrolidinecarboxamide (R)-5-(Hydroxymethyl)-2-pyrrolidinone (S)-5-(Hydroxymethyl)-2-pyrrolidinone (R)-(+)-Lactamide (2R,3R)-Tartranilic Acid [for optical resolution] (3R)-(+)-3-(Trifluoroacetamido)pyrrolidine Hydrochloride (3S)-(-)-3-(Trifluoroacetamido)pyrrolidine Hydrochloride
I0468
I0469
O
Isocyanates
46
O
. HCl
Product No. Product Name A1169 A1170 A1124 A2252 A1342 B3410 B1776 D1539 D3676 E0468 E0452 H1241 H0867 L0167 T1702 T1369 T1366
N H
T1366
O
NH2 OH
N H
CH3
O NCO
5g 1g 1g 1g 1g 5g 1g 1g 1g
I0471 O
O
O
5g 5g 1g 5g
CH3
5g 5g 25g 25g 5g 25g 1g 25g 25g 5g 5g 5g 5g 25g 5g 25g 25g
CH3S
CH3 O OCH3
NCO
CH3
OCH3 NCO
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Chiral Building Blocks
I0334
I0335 CH3
I0473 CH3
NCO
I0466
NCO
I0467
O OCH3
CH3
OCH3
I0465
I0336
O OCH3 NCO
CH3
NCO
CH3
NCO
NCO
OCH3 NCO
Product No. Product Name I0468 I0469 I0471 I0334 I0335 I0473 I0466 I0467 I0472 I0465 I0336 I0398
OCH3 CH3
I0398
O CH3
CH3
NCO
NCO
I0472
O
CH3 O
tBu
Unit Size
Diethyl (S)-(-)-2-Isocyanatoglutarate (S)-(-)-2-Isocyanato-4-(methylthio)butyric Acid Methyl Ester (2S,3S)-2-Isocyanato-3-methylvaleric Acid Methyl Ester (R)-(+)-α-Methylbenzyl Isocyanate (S)-(-)-α-Methylbenzyl Isocyanate Methyl (S)-(+)-2-Isocyanato-3-tert-butoxypropionate Methyl (S)-(-)-2-Isocyanato-3-methylbutyrate Methyl (S)-(-)-2-Isocyanato-4-methylvalerate Methyl (S)-2-Isocyanato-3-phenylpropionate Methyl (S)-(-)-2-Isocyanatopropionate (R)-(-)-1-(1-Naphthyl)ethyl Isocyanate (S)-(+)-1-(1-Naphthyl)ethyl Isocyanate
A0972
1g 1g 1g
5g 5g 5g 25g 5g 1g 5g 25g 5g 5g 5g 5g
5g 1g 1g 5g 1g 1g 1g
A0973
A1230 NH2
CH3
Amino Alcohols
A1231
OH
CH3
NH2
OH NH2 OH
A2306
A1623
A1624
A2307
NH2 OH OH
OH
NH2
A1017
A1521
A1085
OH
D2129
I0462
CH3 Bu
N Bu
OH
I0476
CH3
OH
N Bu
OH
NHCH2
L0137
CH3
CH3 Bu
OH NH2
NH2
NH2
CH2OH
CH3
OH
OH
NH2
D2128
B1119
OH CH3
O2N
NH2
NH2
A2002
OH
OH
OH
NH2
NH2
OH CH3
NH
CH3
OH CH3
NH2
CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
47
Chiral Building Blocks
L0160
M0929
N0608
N0631
P1289
CH3 (CH3)3C
HO
CH3S
OH
CH3
NH2
OH
HO
P1028
P1294
P1274
NH2 OH
P1087
NH2 OH
OH N H
NH2
T1537
V0077
NH2
CH2OH
CH3
CH3
OH
CH3
OH NH2
NH2
Product No. Product Name
Unit Size
(R)-(-)-2-Amino-1-butanol (S)-(+)-2-Amino-1-butanol (1R,2S)-(-)-2-Amino-1,2-diphenylethanol (1S,2R)-(+)-2-Amino-1,2-diphenylethanol (1R,2R)-(-)-1-Amino-2-indanol (1R,2S)-(+)-1-Amino-2-indanol (1S,2R)-(-)-1-Amino-2-indanol (1S,2S)-(+)-1-Amino-2-indanol D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol (1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol (R)-(-)-2-Amino-1-propanol (S)-(+)-2-Amino-1-propanol (+)-cis-2-Benzylaminocyclohexanemethanol (1R,2S)-2-(Dibutylamino)-1-phenyl-1-propanol (1S,2R)-2-(Dibutylamino)-1-phenyl-1-propanol L-Isoleucinol (R)-2-Isopropylamino-2-phenylethanol L-(+)-Leucinol L-tert-Leucinol L-(-)-Methioninol (1R,2S)-(-)-Norephedrine (1S,2R)-(+)-Norephedrine D-Phenylalaninol L-Phenylalaninol (R)-(-)-2-Phenylglycinol (S)-(+)-2-Phenylglycinol D-Prolinol L-Prolinol L-(-)-Tryptophanol D-Valinol L-Valinol
B1953
-Protected Amino Alcohols
5ml 1ml 5ml 1g 5g 1g 5g 1g 5g 1g 5g 1g 5g 1g 5g 25g 500g Price on request 5ml 25ml 1ml 5ml 25ml 1g 5g 1g 5g 1g 5g 1g 5g 5g 25g 5ml 25ml 1g 5g 100mg 1g 25g 25g 5g 25g 5g 25g 5g 25g 5g 25g 1g 5g 25g 5g 25g 1g 1g 5g 5g 25g
B2174
CH3
48
N H
CH2OH
V0058 CH3
OH
A0972 A0973 A1230 A1231 A2306 A1623 A1624 A2307 A1017 A1521 A2002 A1085 B1119 D2128 D2129 I0462 I0476 L0137 L0160 M0929 N0608 N0631 P1289 P1028 P1201 P1294 P1274 P1087 T1537 V0077 V0058
OH NH2
P1201
N H
NH2
NH2
NH2
B2123 OH
OH OC(CH3)3
HN O
N
OC(CH3)3 O
OH N
OC(CH3)3 O
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Chiral Building Blocks
B1966
B2604
B3270
OH HN
B3272
B3076
OH
OC(CH3)3
HN
OH
OC(CH3)3
O
OH
OC(CH3)3
HN
O
O O
B3077
C1609
O
OC(CH3)3
O
C1610
OH
OH
OH
N
HN
HN
O
O O
O
OC(CH3)3
Product No. Product Name
Unit Size
N-(tert-Butoxycarbonyl)-L-alaninol (R)-1-(tert-Butoxycarbonyl)-2-azetidinemethanol (S)-1-(tert-Butoxycarbonyl)-2-azetidinemethanol N-(tert-Butoxycarbonyl)-D-phenylalaninol N-(tert-Butoxycarbonyl)-L-phenylalaninol N-(tert-Butoxycarbonyl)-D-2-phenylglycinol N-(tert-Butoxycarbonyl)-L-2-phenylglycinol N-(tert-Butoxycarbonyl)-D-prolinol N-(tert-Butoxycarbonyl)-L-prolinol N-Carbobenzoxy-D-phenylalaninol N-Carbobenzoxy-L-phenylalaninol
B1953 B2174 B2123 B1966 B2604 B3270 B3272 B3076 B3077 C1609 C1610
OH
N
OC(CH3)3
HN
1g 100mg 100mg 1g
5g 1g 1g 5g 5g 5g 5g 5g 25g 5g 5g
1g 1g 1g 5g 1g 1g
A2049
A1979
A1980
OH H2N
N
Simple Alcohols
OH
H2N
OH
OH
C CH3
OH
O
A0974
A0975
H1200
B2899
HO CH3
H2N
H2N
O
N
OH
B2901
CH2OH
CH3
OH
B2900
B2902
O
OH
CH2
OH
OH
B2141
OH
B2142
B1532 OH
OH O
OH O
OH
B1533
O
OH N
OH
OH
OH
B1159
O
OH
CH2
B1160
B1161
B1343
OH OH N CH2
CH3
OH
CH3
OH
OH
OH OH
CH3
CH3 OH
CH3
CH3
OH
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
49
Chiral Building Blocks
B2404
B0926
B0925
B3054
B3055 OH
HO
OH
CH3
CH3
OH
CH3
B2909
(CH3)3CHN
B2910
CH3
HC C
D1589
O
O
NC
CH3
H0950
CH3
O
CH3
H0951
O
O
M1788
N CH3
OH
OH
50
CH3
O
OH
O OCH3
O OCH3
CH3
N0784
N0785 OH
OH
CH3 O
CH3
O0235
OH CH3
CH3
O
O0144
OH CH3
CH3
HO CH3
O0145
CH3
O CH3
H0704
OH OCH3
M1374
CH3
OH
T1716
CH3
O
Cl
OH
O0293
O
OH
M1938
N
CH3
CH3
OH
H0705
OH
OH
OH
CH3
HO
OH
M1937
OH CH3
OH
O
O
OH
CH3
H0969
H0887
M1483
CH3O O
CH3
O O
OH O
O
M1790
CH3O
CH3
Cl
HO
OH
O
O
O
H0939
OH
OH
H1032
CH3
O OH
O
OH
OH
O
O
C1717
OH
H0975
OH O
O
HO
H1029
OH
OH
Cl
OH
C1474
OH
SH
OH
CH3
D2239
C1733
OH HS
O
O
CH3
OH
E0455
OH
CH3
O
OH
OH
D2240
N
C O C CH3
Cl
HC C
OH
CH3
C O C CH3
M0967
CH3
OH
O
N OH
OH
B1987
OH
CH3
CH3
CH3
P1411
C OH
CH
CH3
CH3 OH
OH
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Chiral Building Blocks
P1412
P0744
CH3
P0743
CH3 OH
T1491
OH
OH CH3
CH3
OH
T1490
CH3
CH3
OH
P1150
P1151 OH
HO
P0795 OH
HO
P0796 CH3
P1417 CH3
OH
OH
OH OH CH3
P1780
P1152
P1129
CH3
OH
OH
P1140
OH
OH OH
S0038
P1667 OH
CH3
OH
CH3
P1608
N H
T2359
N H
T2360
T1499
O C OH
OH
OH
OH
OH
. HCl
N H
HO
OH
OH OH
T1482 OH
OH
Product No. Product Name A2049 A1979 A1980 A0974 A0975 H1200 B2899 B2900 B2901 B2902 B2141 B2142 B1532 B1533 B1159 B1160 B1161 B1343 B2404 B0926 B0925 B3054 B3055 B1987
(R)-1-Acetyl-3-pyrrolidinol (R)-3-Amino-1,2-propanediol (S)-3-Amino-1,2-propanediol (R)-(-)-1-Amino-2-propanol (S)-(+)-1-Amino-2-propanol (3R,4R)-1-Benzyl-4-hydroxy-3-pyrrolidinemethanol (R)-4-Benzyloxy-1,2-butanediol (S)-4-Benzyloxy-1,2-butanediol (R)-4-Benzyloxy-1,3-butanediol (S)-4-Benzyloxy-1,3-butanediol (R)-(+)-3-Benzyloxy-1,2-propanediol (S)-(-)-3-Benzyloxy-1,2-propanediol (R)-1-Benzyl-3-pyrrolidinol (S)-1-Benzyl-3-pyrrolidinol (R)-(-)-1,3-Butanediol (S)-(+)-1,3-Butanediol (R,R)-(-)-2,3-Butanediol (S,S)-(+)-2,3-Butanediol (S)-1,2,4-Butanetriol (R)-(-)-2-Butanol (S)-(+)-2-Butanol (R)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol (S)-1-(tert-Butoxycarbonyl)-3-pyrrolidinol (S)-(-)-3-tert-Butylamino-1,2-propanediol
Unit Size
1g
1g 1g 5g 1g 200mg 200mg
100mg 100mg 1g 5g 1g 1g 1g 100mg 5g 1ml 1ml 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
1g 5g 5g 25g 5g 200mg 1g 1g 1g 1g 1g 1g 5g 25g 5g 5g 5g 1g 25g 5ml 5ml 5g 5g 5g
51
Chiral Building Blocks
Product No. Product Name B2909 B2910 M0967 D2239 D2240 D1589 E0455 C1733 C1717 C1474 H1029 H0975 H1032 H0969 H0950 H0951 H0939 H0887 T1716 M1788 M1790 M1483 H0705 H0704 M1937 M1938 M1374 N0784 N0785 O0293 O0145 O0144 O0235 P1411 P1412 P0744 P0743 T1490 T1491 P1150 P1151 P0795 P0796 P1417 P1780 P1152 P1129 P1608 P1667 P1140 S0038 T2359 T2360 T1499 T1482
Unit Size
(R)-(+)-3-Butyn-2-ol (S)-(-)-3-Butyn-2-ol (R)-(-)-3-Chloro-1,2-propanediol (+)-1,4-Di-O-benzyl-D-threitol (-)-1,4-Di-O-benzyl-L-threitol L-Dithiothreitol D-Erythronolactone Ethyl (R)-4-Chloro-3-hydroxybutyrate Ethyl (S)-4-Chloro-3-hydroxybutyrate Ethyl (R)-(-)-4-Cyano-3-hydroxybutyrate Ethyl (R)-(-)-3-Hydroxybutyrate Ethyl (S)-(+)-3-Hydroxybutyrate (2R,5R)-2,5-Hexanediol (2S,5S)-2,5-Hexanediol (R)-(+)-α-Hydroxy-γ-butyrolactone (S)-(-)-α-Hydroxy-γ-butyrolactone (S)-3-Hydroxy-γ-butyrolactone (S)-(+)-3-Hydroxy-2,2-dimethylcyclohexanone (S)-3-Hydroxytetrahydrofuran (R)-4-(4-Methoxybenzyloxy)-1,2-butanediol (S)-4-(4-Methoxybenzyloxy)-1,3-butanediol Methyl (R)-4-Chloro-3-hydroxybutyrate Methyl (R)-(-)-3-Hydroxybutyrate Methyl (S)-(+)-3-Hydroxybutyrate (R)-1-Methyl-3-pyrrolidinol (S)-1-Methyl-3-pyrrolidinol D-Mevalonolactone (R)-(+)-1-(2-Naphthyl)ethanol (S)-(-)-1-(2-Naphthyl)ethanol (3R,6R)-3,6-Octanediol (R)-(-)-2-Octanol (S)-(+)-2-Octanol (S)-1-Octyn-3-ol [ω Side-Chain Unit for PG Synthesis] (2R,4R)-(-)-2,4-Pentanediol (2S,4S)-(+)-2,4-Pentanediol (R)-(-)-2-Pentanol (S)-(+)-2-Pentanol (1R,2S)-(-)-trans-2-Phenyl-1-cyclohexanol (1S,2R)-(+)-trans-2-Phenyl-1-cyclohexanol (R)-(-)-1-Phenylethane-1,2-diol (S)-(+)-1-Phenylethane-1,2-diol (R)-(+)-1-Phenylethyl Alcohol (S)-(-)-1-Phenylethyl Alcohol (R)-1-Phenyl-2-propanol (S)-1-Phenyl-2-propanol (R)-(-)-1,2-Propanediol (S)-(+)-1,2-Propanediol (R)-3-Pyrrolidinol (S)-3-Pyrrolidinol (R)-(-)-3-Pyrrolidinol Hydrochloride Shikimic Acid (R)-(-)-1,2,3,4-Tetrahydro-1-naphthol (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol (R)-(+)-1,1,2-Triphenyl-1,2-ethanediol (S)-(-)-1,1,2-Triphenyl-1,2-ethanediol
10g
1g
1g 100mg 100mg 1g 1g
10ml 5ml 1g 1g
5ml 5ml 1g
1ml 1ml 100mg 100mg 1g 5g 1g 1g 5g 1g 5g
5g 1g 5g 5g 100mg 1g 100mg 100mg 1g 1g
A1445
A2323
A2324 NH2
NH2
Amines
52
O
O
1g 5g 5g 5g 5g 1g 5g
1g
. HCl
1g 1g 25g 1g 1g 5g 25g 25g 25g 25g 5g 25g 1g 5g 1g 1g 5g 100mg 5g 500mg 500mg 5g 25ml 25ml 5g 5g 1g 1g 1g 500mg 25ml 25ml 5g 1g 1g 5ml 5ml 1g 1g 25g 5g 25g 25g 1ml 1ml 25g 5g 5g 25g 25g 5g 1g 1g 5g 1g
N
NH2
. HCl
. HCl
N
C OCH2
C OCH2
O
O
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Chiral Building Blocks
A1342
A1301
A1167
A1053
NH2
H
NH2
N
N
CH2CH3
A1174
CH3
CH2
CH2
B1583
NHCH2CH3
N
N
CH2
B1582
NHCH2CH3
NH C O C CH3
N
CH2
B1581
B1580 CH3
O
NH2
N
B2775
NHCH3
B2776 CH3
NHCH3
CH3
NH2
N
N
CH2
NH2
CH3
N
CH2
CH3 NH2
CH2
CH3
CH3 NH2
. xH3PO4
CH3
B3225
B2316 OCH3
NH2
NH2
CH3O
B2317
CH3
CH3
B2920
CH3 NH2
CH3
CH3 CH3
NH2
CH3
B2921
CH3
CH3
CH3
N
C O C CH3 O
CH3
C O C CH3
CH3
O
C1575
CH3
C O C CH3
CH3
CH3
CH3
N H
N H
B2917
B2918
O
CH2O C HN O
C1189
D2459
CH3
CH3
CH3
CH3
NH2
O
C1541
NH2
NH2
NH2
D2828
CH3
NH
O
CH3
NH2
D2827
O
O
CH3 C O C HN
C1448
O
O
NH
NH2
CH3
C1447
H 2N
O
CH3
C O C CH3
NH2 CH3
N
O NH
B1995
NH2
A1172
CH3
NH2
. xH3PO4
CH3
A1171 CH3 NH2
. 2HCl
N H
B1932
NH2
NH2
NH2
N H
N H
A1173
. 2HCl
NH2
CH2NH2
CH2CH3
A1054
N H
A1168
NH2
NH2
D2460
NHCH3
NHCH3
NHCH3
NH2
. 2HCl
NH2
NH2
CH3
CH3
N CH3
N CH3
N H
N H
D2175 NH2
CH3
D2193
NH2
NH2
D2176
NHCH3
CH3
D2149
CH3
. 2HCl
C1531
E0433 NHCH2CH3
NH2
NH2
N H
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
53
Chiral Building Blocks
E0434
M1511
M1512 CH3
NH2
M1107 CH3
M1108
NH2
NHCH2CH3
NHCH3
N H
N H OCH3
M1746 CH2NH2
M2091
CH3
CH2NH2
N0482
N0726 NH2
CH3
P0793 CH3
CH3
NH2
NH2
P1118 CH3
NH2
CH3 NH2
CH3
T1380
T1381 CH3
NH2
CH3
CH3
NH2
CH3
Product No. Product Name A1445 A2323 A2324 A1342 A1301 A1167 A1168 A1053 A1054 A1173 A1174 B1932 B1580 B1581 B1582 B1583 B2775 B2776 B3225 B2316 B2317 A1171 A1172 B2920 B2921 B1995 B2917 B2918 C1575 C1447 C1448 C1541
54
NH2
CH3
P0794
NH2
N0481 CH3
H N N H
N0724
N H
OCH3
M1747
CH3
NHCH3
(S)-(-)-α-Amino-γ-butyrolactone Hydrochloride (R)-3-Amino-1-carbobenzoxypyrrolidine Hydrochloride (S)-3-Amino-1-carbobenzoxypyrrolidine Hydrochloride (R)-(+)-2-Aminomethyl-1-ethylpyrrolidine (S)-(-)-2-Aminomethyl-1-ethylpyrrolidine (3R)-(+)-3-Aminopyrrolidine (3S)-(-)-3-Aminopyrrolidine (3R)-(-)-3-Aminopyrrolidine Dihydrochloride (3S)-(+)-3-Aminopyrrolidine Dihydrochloride (3R)-(-)-1-Benzyl-3-aminopyrrolidine (3S)-(+)-1-Benzyl-3-aminopyrrolidine (3R)-(+)-1-Benzyl-3-(tert-butoxycarbonylamino)pyrrolidine (3R)-(-)-1-Benzyl-3-(ethylamino)pyrrolidine (3S)-(+)-1-Benzyl-3-(ethylamino)pyrrolidine (3R)-(-)-1-Benzyl-3-(methylamino)pyrrolidine (3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine (1R,2R)-1,2-Bis(3,5-dimethylphenyl)-1,2-ethylenediamine Phosphate (1S,2S)-1,2-Bis(3,5-dimethylphenyl)-1,2-ethylenediamine Phosphate (1R,2R)-1,2-Bis(4-methoxyphenyl)ethylenediamine (1R,2R)-1,2-Bis(2,4,6-trimethylphenyl)ethylenediamine (1S,2S)-1,2-Bis(2,4,6-trimethylphenyl)ethylenediamine (3R)-(+)-3-(tert-Butoxycarbonylamino)pyrrolidine (3S)-(-)-3-(tert-Butoxycarbonylamino)pyrrolidine (3R)-(+)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine (3S)-(-)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine N-(tert-Butoxycarbonyl)-L-serine β-Lactone (R)-(-)-sec-Butylamine (S)-(+)-sec-Butylamine N-Carbobenzoxy-L-serine β-Lactone (1R,2R)-(-)-1,2-Cyclohexanediamine (1S,2S)-(+)-1,2-Cyclohexanediamine (R)-(-)-1-Cyclohexylethylamine
Unit Size 1g 1g 1g 1g 5g 5g 5g 5g 10g 10g
5g 5g
100mg 100mg 5g 5g 1g 1g 1g 100mg 1g 5g 5g 5g
1g 5g 5g 5g 5g 25g 25g 25g 25g 25g 25g 5g 5g 5g 25g 25g 100mg 100mg 1g 500mg 500mg 25g 25g 5g 5g 5g 1g 5g 1g 25g 25g 25g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Chiral Building Blocks
Product No. Product Name C1531 C1189 D2827 D2828 D2149 D2193 D2459 D2460 D2176 D2175 E0433 E0434 M1511 M1512 M1107 M1108 M1746 M1747 M2091 N0482 N0481 N0724 N0726 P0794 P0793 P1118 T1380 T1381
Unit Size
(S)-(+)-1-Cyclohexylethylamine D-(+)-Cycloserine (R)-1,2-Diaminopropane Dihydrochloride (S)-1,2-Diaminopropane Dihydrochloride (3R)-(+)-3-(Dimethylamino)pyrrolidine (3S)-(-)-3-(Dimethylamino)pyrrolidine (1R,2R)-(-)-N,N '-Dimethylcyclohexane-1,2-diamine (1S,2S)-(+)-N,N '-Dimethylcyclohexane-1,2-diamine (1R,2R)-(+)-1,2-Diphenylethylenediamine (1S,2S)-(-)-1,2-Diphenylethylenediamine (3R)-(+)-3-(Ethylamino)pyrrolidine (3S)-(-)-3-(Ethylamino)pyrrolidine (R)-(+)-1-(4-Methoxyphenyl)ethylamine (S)-(-)-1-(4-Methoxyphenyl)ethylamine (3R)-(+)-3-(Methylamino)pyrrolidine (3S)-(-)-3-(Methylamino)pyrrolidine (R)-(+)-β-Methylphenethylamine (S)-(-)-β-Methylphenethylamine (R)-(-)-2-Methylpiperazine (R)-(+)-1-(1-Naphthyl)ethylamine (S)-(-)-1-(1-Naphthyl)ethylamine (R)-1-(2-Naphthyl)ethylamine (S)-1-(2-Naphthyl)ethylamine (R)-(+)-1-Phenylethylamine (S)-(-)-1-Phenylethylamine (S)-1-Phenyl-2-(p-tolyl)ethylamine (R)-(+)-1-(p-Tolyl)ethylamine (S)-(-)-1-(p-Tolyl)ethylamine
5g 1g
1g 1g 100mg 100mg 1g 1g 1g
5g 5g 1g 1g 5g 5g 5g 1g 1g 1g 1g 25ml 25ml 5g 1ml 1ml
D2265
D3758 O
CH3
CH3
O
O O
D1949 O
CH3
O
O O
I0507
CH3 COOH
CH3
CH3
O
CH3 O
O
CH3
CH3 CH3
O
H3C CH3
O
O
CH3
O O
O
O
CH3
O O
OH
I0688
CH3 CH3
O
HO
O
O
H3C
CH3
I0489 O
OH
OH
OH
HO
O
CH2OH
O
OH
O
I0400
O
HOH2C
O
O O
CH3 CH3
I0375
O
CH3
D2616
2
O
I0376
O
CH3
O
CH3
O
CH3
CH3
HO
OH
HOCH2
O
CH3
O
CH3
OH
O
OH O
CH3 O
.HO
CH3
O
HO
O
OH
I0454 O
CH3 CH3
D2447
O
O
CH3 CH3
O
CH3 CH3
O O
O
O
O
CH3
CH3
D2024
OH
CH3
O
O O
HO
D2191
CH3
D2555
CH3
Isopropylidene Sugars
25g 5g 1g 1g 5g 5g 1g 5g 5g 5g 1g 1g 25g 25g 5g 5g 25g 25g 25g 5g 5g 5g 5g 500ml 500ml 25g 5ml 5ml
O O
CH2OH O
CH3
O
CH3 CH3
CH3
I0721 CH2OH
HOCH2 O
HO
OH O
O
CH3 CH3
O O
CH3 CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
55
Chiral Building Blocks
Product No. Product Name
Unit Size
1,2:5,6-Di-O-isopropylidene-α-D-allofuranose 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose 1,2:3,4-Di-O-isopropylidene-α-D-galactopyranose 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose (-)-2,3:4,6-Di-O-isopropylidene-2-keto-L-gulonic Acid Monohydrate 1,2:5,6-Di-O-isopropylidene-D-mannitol 2,3:5,6-Di-O-isopropylidene-D-mannofuranose 1,2:3,5-Di-O-isopropylidene-α-D-xylofuranose (+)-5,6-O-Isopropylidene-L-ascorbic Acid 2,3-O-Isopropylidene-D-erythronolactone 1,2-O-Isopropylidene-α-D-glucofuranose 1,2-O-Isopropylidene-α-D-glucurono-6,3-lactone 3,4-O-Isopropylidene-D-mannitol (+)-2,3-O-Isopropylidene-L-threitol (-)-2,3-O-Isopropylidene-D-threitol 1,2-O-Isopropylidene-α-D-xylofuranose
D2265 D3758 D2555 D1949 D2191 D2024 D2447 D2616 I0507 I0454 I0400 I0688 I0489 I0376 I0375 I0721
B2136
1g 5g 5g 10g 5g
1g 1g 1g 5g
B2137
C2265
CH2OCH2
Protected 1,2-Diols
C1796
O
D1705
O
CH3 CH3
D1691
O
O
CH3
H1188
O
O
CH3 CH3
HOCH2CH2
O
O CH3
M1451
HOCH2CH2
O
CH3 CH3
O
O
CH3 CH3
H1189
O
CH3
O CH2O
O
CH3OCH2 CH3
O
O
O
CH2O O
CH3
O
CH3
S O
CH3
CH3
P1485
CH3OCH2
O
CH3
O CH3
S O
M1456
CH3
CH3 O
D2550
CH2OH
O CH3
O
CH3
D2549
CH2OH
ClCH2
ClCH2
CH2OCH2 O
5g 25g 25g 25g 25g 25g 5g 5g 5g 1g 25g 1g 5g 5g 5g 25g
CH3
O O
O O
O
O
P1486
CH3
O O
O
Product No. Product Name B2136 B2137 C2265 C1796 D1705 D1691
56
(R)-4-Benzyloxymethyl-2,2-dimethyl-1,3-dioxolane (S)-4-Benzyloxymethyl-2,2-dimethyl-1,3-dioxolane (R)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane (S)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol
Unit Size 5g 1g 1g
5g 5g
1g 1g 25g 5g 25g 25g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Chiral Building Blocks
Product No. Product Name D2549 D2550 H1188 H1189 M1451 M1456 P1485 P1486
Unit Size
(R)-(-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate (R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane (S)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane (R)-(+)-4-(Methoxymethyl)-1,3-dioxolan-2-one (S)-(-)-4-(Methoxymethyl)-1,3-dioxolan-2-one (R)-Propylene Carbonate (S)-Propylene Carbonate
B2238
1g 1g
5g 5g 5g 5g
B2239
CH2OCH2
Glycidyl Compounds
E0533
G0363
E0581
CH2Cl
CH2OCH2 O
O
O
G0364
G0282
G0283 O
CH2OH
CH2Cl
CH2OH
O
O
CH2O C
O
G0286
O
G0287
G0327
O
CH2O S
CH2O S
O
O
O
G0328
T1611
N CH2
O
O
O
T1612
O
NO2
NO2 O
CH2OCH3
O
(CH2)2CH3
O
G0281
CH2OCH3
CH2O C
(CH2)2CH3
O
G0280
5g 5g 1g 1g 25g 25g 25g 25g
O
G0284
G0285
O O
N CH2
O
O CH3
CH2O S O
O
O
O
P1396
CH3
CH2O
CH2O
C
C
O
O
O
P0951
CH3
CH3 O
O
Product No. Product Name B2238 B2239 E0581 E0533 G0363 G0364
CH2O S
Benzyl (R)-(-)-Glycidyl Ether Benzyl (S)-(+)-Glycidyl Ether (R)-Epichlorohydrin (S)-Epichlorohydrin (R)-(+)-Glycidol (S)-(-)-Glycidol
Unit Size 1g 1g
5g 5g 5g 5g 5g 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 25g 25g 25g 25g 25g
57
Chiral Building Blocks
Product No. Product Name G0282 G0283 G0280 G0281 G0286 G0287 G0327 G0328 T1611 T1612 G0284 G0285 P1396 P0951
Unit Size
(R)-Glycidyl Butyrate (S)-Glycidyl Butyrate (R)-Glycidyl Methyl Ether (S)-Glycidyl Methyl Ether (R)-Glycidyl 3-Nitrobenzenesulfonate (S)-Glycidyl 3-Nitrobenzenesulfonate (R)-N-Glycidylphthalimide (S)-N-Glycidylphthalimide (2R)-(-)-Glycidyl p-Toluenesulfonate (2S)-(+)-Glycidyl p-Toluenesulfonate (R)-Glycidyl Trityl Ether (S)-Glycidyl Trityl Ether (R)-(+)-Propylene Oxide (S)-(-)-Propylene Oxide
1ml
A1576
B2420
CN
OH
Others
O
N
CH3
C1188
N
C
H
B1759
25g 25g 25g 25g 25g 25g 25g 25g 25g 25g 25g 25g 25ml 25ml
B3299 H
O
H2N
B2779
5g 5g 5g 5g 5g 5g 5g 5g 5g 5g 5g 5g 5ml 5ml
CH2
C1363
D3259
CH3 O
Si C(CH3)3
O
O
H C
CH3
N
CH3 BrHC
O
Si C(CH3)3
O
CH3
CN
C O C CH3 CH3
CH3
Cl
CH3
N
N
CH3
CH3
CH3 CH3
O
CH3
D3257
M0803 OCH3
N CH3O
N
CH
M1622
CH3OCH2
CH3
M0824 O OH H N
CH3 O
M0170
HO
M1233
HO
OH H N
OH CH3
CH3
M1234
OH
CH3
OH CH3
M0963
CH3
O
M0965
CH3
P1499
CH3
M0964
CH3
M0966
CH3
CH3
OH
P1500
CH3
P1504
OH CH3
CH3
OH
O
O
O
N O
O
P1509
O
CH3 CH3
OH O
T2551
T2552
T2636
H3C O
CH2NH2
O
O
O
CH2NH2 O
58
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Chiral Building Blocks
Product No. Product Name A1576 B2420 B3299 B2779 B1759 C1188 C1363 D3259 D3257 M0803 M1622 M0824 M1233 M1234 M0170 M0965 M0964 M0966 M0963 P1499 P1500 P1504 P1509 T2551 T2552 T2636
(R)-4-Amino-2-methyl-1-butanol (4aS,8aR)-2-Benzoyloctahydro-6(2H)-isoquinolinone (R)-1-Benzyl-3-pyrrolidinecarbonitrile (1R,3R)-5-(Bromomethylene)-1,3-bis(tert-butyldimethylsilyloxy)cyclohexane (S)-(-)-3-(tert-Butoxycarbonyl)-4-formyl-2,2-dimethyl-1,3-oxazolidine (S)-(+)-1-Chloro-2-methylbutane (-)-2-Cyano-6-phenyloxazolopiperidine (5S)-5,6-Dihydro-6,6-dimethyl-5-phenyl-2H-1,4-oxazin-2-one (2S)-2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazine (4S,5S)-(-)-4-Methoxymethyl-2-methyl-5-phenyl-2-oxazoline (R)-(+)-N-(α-Methylbenzyl)phthalamic Acid (S)-(-)-N-(α-Methylbenzyl)phthalamic Acid (R)-(+)-2-Methyl-1,4-butanediol (S)-(-)-2-Methyl-1,4-butanediol (S)-(-)-2-Methyl-1-butanol (S)-(+)-5-Methyl-1-heptanol (S)-(+)-4-Methyl-1-hexanol (S)-(+)-6-Methyl-1-octanol (S)-(+)-3-Methyl-1-pentanol (R)-3-Phenylcyclohexanone (S)-3-Phenylcyclohexanone (R)-3-Phenylcyclopentanone (S)-3-Phenylcyclopentanone (R)-(-)-Tetrahydrofurfurylamine (S)-(+)-Tetrahydrofurfurylamine (R)-(-)-2,3,7,7a-Tetrahydro-7a-methyl-1H-indene-1,5(6H)-dione
Unit Size 1g 1g 1g 10ml
5g
1ml 1ml 1ml 100mg 100mg 100mg 100mg 200mg 200mg 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 50mg 5g 100mg 5g 25ml 1g 1g 1g 1g 5g 1g 5g 25g 25ml 1ml 5ml 5ml 5ml 1g 1g 1g 1g 1g 1g 5g
59
Optical Resolution
Optical Resolution The optical resolution is the method of separating enantiomers from racemates. There are currently many methods to obtain optically active compounds. These methods include asymmetric synthesis, use of chiral building blocks, and optical resolution. In recent years, there has been rapid improvements in asymmetric synthesis, with many reports of success. Optical resolution is widely used, as it is an easy and practical method. One of the most common optical resolution methods utilizes diastereomer which are obtained from the reaction of racemic compounds and an optical resolving agents. The differences of physical properties between diastereomers are utilized in this method. The optical resolving agents are often easily obtained from natural products. For example, alkaloids are used for the optical resolution of racemic acids and tartaric acid is used for the optical resolution of racemic bases. In both cases, diastereomeric salts are formed. When alcohols are to be resolved, the alcohols are reacted with phthalic anhydride to form half ester. The resulting carboxylic acid (half ester) is often then reacted with alkaloids to form diastereomeric salts, which are then resolved. Recently, Ikegami and co-workers have reported a new resolution method for alcohols using amino acid derivatives.1) According to their report, racemic 1-octyn-3-ol is reacted with ( )- - toluenesulfonylphenylalanyl chloride (1), to produce diastereomeric ester. This diastereomeric ester is recrystallized four times from mixed solution of ethanol and hexane, giving the resolved ester with a theoretical yield of 64% (>99% d.e.). Finally, ( )-1-octyn-3-ol is obtained by hydrolysis of pure diastereomeric ester (>99% e.e.). This method is drawing attention as an easy and accurate way to optically resolve alcohols. O
O PhCH2
C Cl
i)
NHTs
PhCH2
C O NHTs
1
ii) recrystallization
OH
Y.64% ( >99% d.e.)
40% KOH aq.
OH
On the other hand, it has been reported that optical resolution is achieved by catalytic amount of chiral source. Ishihara and co-workers have studied minimal artificial enzymes to overcome various problems of enzymatic reactions and to use optical resolution. One reagent that has been developed is α-(2,4,6triisopropylbenzenesulfonyl)- -( -butyldimethylsilyl)-π-methyl-L-histidinol (2). They reported that this reagent was a very effective catalyst for kinetic resolution of racemic alcohols by selective acylation2). This reagent can also be used as catalyst for the kinetic resolution of 1,2-diols, β-hydroxycarboxylic acids, and 2-amino alcohols after the suitable derivatization. H3C N
OTBDPS HN
N
SO2
i-Pr
i-Pr
2 O O C N
(5 mol%)
i-Pr
O
O
O C N
O C N
(i-PrCO)2O (0.5 eq.)
OH syn, racemic
60
i-Pr2NEt (0.5 eq.) nonpolar solvent (49% conv.)
+ O C 94% e.e.
O
i-Pr
OH 90% e.e.
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Optical Resolution
Shiina and co-workers developed the kinetic resolution of racemic alcohols and racemic carboxylic acids using 4-methoxybenzoic anhydride (PMBA) (3) and a Birman-type asymmetric catalyst3) [(+)-benzotetramisole, (+)-BTM].4) For example, in the reaction of racemic alcohols with achiral carboxylic acids, first the mixed anhydrides are formed from PMBA and the carboxylic acids. Subsequently the mixed anhydrides and one enantiomer of racemic alcohol react preferentially to form optically active esters and optically active alcohols using catalyst (+)-BTM. If this reaction is performed replacing the reactive substrates with racemic carboxylic acids and achiral alcohols, the kinetic resolution proceeds efficiently and optically active esters and optically active carboxylic acids can be obtained. The optical resolution of an anti-inflammatory agent, ibuprofen, has been achieved as an example of this reaction. O
O O O
OH
R2
O CH3O
R1
+ R2CO2H
3
OH
R1
O
3
+ R3OH
R1
+
(+)-BTM (cat.), iPr2NEt, CH2Cl2, rt
O
OH
OCH3
O OR
i
(+)-BTM (cat.), Pr2NEt, CH2Cl2, rt
CH3
+
3
OH
CH3
CH3
BTM=(+)-Benzotetramisole
A1230
A1231
A1017
OH
for Resolution of Acids
A1521
A0526
NH
OH
H2N
NH2
B3549
OH
OH
A1029 OH
OH
NH2
NH2
O
N H
OH H2N
B1119
O
B3296
N H
OH
H
H
CH2OH
CH3O
N H
S
N
NHCH2
CH3O
NHCH2
N
H
C0348 CH2 CH
HO
H
N
H
C0349 CH2 CH
HO
H
H
N
HO
H
N
CH3O
N
CH2
H
O
O
H O H . HCl . H2O
H
H CH2
CH
CH N
N
N
H
. 2H2SO4 . 2H2O N
N H
C0351
H
HO
. 2HCl N
H
C0350 CH2 CH
CH3O
H
O
C0347
N
B0671
B0946 B0670
CH2OH
N
S
. HCl
NH2
NH2
B1118
N
O
NH
OH H2N
N H
NH2
O2N
A0528
NH
NH2
HO
H
. HCl . xH2O N
N
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
61
Optical Resolution
C0791
D1588
H0752
CH2
L0129 CH3CH2
CH3
H
L0131
H
CH
HO
. H2SO4 . 2H2O
H
CH3
N
H2N
H
M0826
H2N
H2N
OH
M0545
OH
. HCl
NH2
N0543 CH3
CH3
OH
. HCl
NH2
CH3
N0482
N0481
CH3
CH3
CH3
P0794 CH3
NH2
P1118
Q0006
Q0010
Q0028
H
NH2
NH2
CH3
H
N
N HO
S0249
. HCl . 2H2O
N O
N
S0093
S0094
H
H H
O
O
H
H
H N
H H
N
N
H N
O
. HCl . xH2O
O
N
H
H H
O
. HNO3
O
H
H H
O
NH2
CH3
CH3
NH2
CH3
Product No. Product Name A1230 A1231 A1017 A1521 A1029 A0526 A0528 B3296 B3549 B1119 B1118 B0946 B0670 B0671
(1R,2S)-(-)-2-Amino-1,2-diphenylethanol (1S,2R)-(+)-2-Amino-1,2-diphenylethanol D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol (1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol D-(-)-Arginine L-(+)-Arginine L-(+)-Arginine Hydrochloride (+)-Benzotetramisole (-)-Benzotetramisole (+)-cis-2-Benzylaminocyclohexanemethanol (-)-cis-2-Benzylaminocyclohexanemethanol Brucine Anhydrous Brucine Dihydrate Brucine Hydrochloride
2
. H2SO4 . 5H2O
T1381 CH3
62
N
CH3O N
N
H
N
T1380
H
2
N
S0257
HO
H
N HO
. H2SO4 . 2H2O
H
CH3O
CH3O
H
CH
N
CH
CH2 CH
H CH2
HO
NH2
OH NH2
CH2 CH
Q0030
NO2
P1028
NH2
P0793
. HCl
CH3
OH
CH3O
NH2
OH
P1289
NH2
H
. 2HCl
O
O
CH2
OH NH2
NH2
CH3
CH3
H2N
N
L0071
CH3
O
OH
. HCl
NH2
L0128
H
CH3O
2
N
O
CH3
CH3
N HO
Unit Size 1g 5g 1g 5g 25g 500g Price on request 1g 5g 25g 500g 25g 500g 200mg 1g 1g 1g 5g 1g 5g 25g 25g 5g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Optical Resolution
Product No. Product Name C0347 C0348 C0349 C0350 C0351 C0791 D1588 H0752 L0129 L0131 L0128 L0071 M0826 M0545 N0543 N0482 N0481 P1289 P1028 P0794 P0793 P1118 Q0006 Q0010 Q0028 Q0030 S0249 S0257 S0093 S0094 T1380 T1381
Unit Size
Cinchonidine Cinchonidine Dihydrochloride Cinchonidine Sulfate Cinchonine Cinchonine Hydrochloride Hydrate Cinchonine Sulfate Dihydrate (+)-Dehydroabietylamine Hydroquinidine Hydrochloride L-(+)-Lysine L-(+)-Lysine Dihydrochloride D-(-)-Lysine Monohydrochloride L-(+)-Lysine Monohydrochloride (+)-Menthol (-)-Menthol (S)-α-Methyl-4-nitrobenzylamine Hydrochloride (R)-(+)-1-(1-Naphthyl)ethylamine (S)-(-)-1-(1-Naphthyl)ethylamine D-Phenylalaninol L-Phenylalaninol (R)-(+)-1-Phenylethylamine (S)-(-)-1-Phenylethylamine (S)-1-Phenyl-2-(p-tolyl)ethylamine Quinidine Quinidine Sulfate Dihydrate Quinine Quinine Hydrochloride Dihydrate Strychnine Strychnine Hydrochloride Hydrate Strychnine Nitrate Strychnine Sulfate Pentahydrate (R)-(+)-1-(p-Tolyl)ethylamine (S)-(-)-1-(p-Tolyl)ethylamine
25g
250g 25g 500g 200g 25g 500g 25g 250g 25g 25g 25g 500g 500g 500g 1g 5g 5g 25g 25g 500ml 500ml 25g 25g 25g 500g 25g 25g 25g 25g 25g 5ml 5ml
25g 25g 25g 5g 25g 5g 5g 25g 25g 25g 1g 1g 5g 5g 25ml 25ml 5g 5g 5g 25g
1ml 1ml
A1454
A1453 O
O
CH3 C O
A0545 O
C OH
O
CH3 C O
O
C OH HO
for Resolution of Bases
A0546
B1121
HO
OH O
B1120
C OH
C OH
O
O NH
NH C
NH2
C0012
C0015
CH3
CH3 CH3 COOH COOH
CH3 O
B1143
NH2
B1144
O
O
O
OH O
O O
O
P OH
O
O P OH
C
C0972 CH3 CH2SO3H
O
C0998
CH3 HO3SCH2
CH3 O
C1308
CH3
CH3 CH2SO2Cl
O
CH3 ClSO2CH2
CH3 O
H
C1417
C1418
D2636
D1386
H
O
H
O
O H
O
O CH3
H
O
CH3
O
HO
OH O
D1911 O
O
CH3
O
O O
O O
CH3 C O
O
HO
O
OH O
O
CH3 O
O
CH3 C O
O
O
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
63
Optical Resolution
D2645
D1398
D3826
D1354
O
O O
CH3 C O
O CH3 C O
Ph
O
O
HO O
O
D3492
O
O
O
HOOC
COOH
Ph
O
O
HO
OH . H2O
C O
Ph
O
O C O
O
O
O
D1853
D1387 O
p-Tol
OH
NO2
M0021
p-Tol
O
O
OH O
O OH
O
OH
NH2
M0661
HO
O HO
OH
NH2
M1221 CH3
O
O
OH
O
HO
O
M0662
O
O
HO
p-Tol
O
O
M0022
HO
O
G0059
O
O
HO
OH O
O2N
O
G0057
p-Tol
O
HO
O
Ph
COOH O C
O
O
HN
C O
O
D1417 O
HOOC
OH . H2O
HO
C OH
C OH O
OH O
O C Cl
OH CH3
M0990
M1021
I0334
CH3
CH3
CH3
M1622 CH3
NCO
O
NCO
OH H N
OH
O O C Cl
O
CH3O
CH3
I0335
O
CH3
M0824
I0336 O
I0398 CH3
NCO
P1354 CH3
P0573
O
N H
OH
O
O
T0026
T0025
T1702
O
T1163 NO2
O HO C OH
OH
HO
OH
OH
O
HO
OH O
OH
O
HO
OH
H N
OH
OH O
OH
O
NO2
O O2N
NO2 N
OH
O OH
CH3
OH
O
Product No. Product Name
64
OH
N H
CH3
Q0009
A1454 A1453 A0545 A0546 B1121 B1120 B1143 B1144 C0012 C0015 C0972 C0998 C1308 C1417
CH3
NCO
OH H N O
CH3
(+)-O-Acetyl-L-mandelic Acid (-)-O-Acetyl-D-mandelic Acid D-Aspartic Acid L-Aspartic Acid (+)-cis-2-Benzamidocyclohexanecarboxylic Acid (-)-cis-2-Benzamidocyclohexanecarboxylic Acid (R)-(-)-1,1'-Binaphthyl-2,2'-diyl Hydrogen Phosphate (S)-(+)-1,1'-Binaphthyl-2,2'-diyl Hydrogen Phosphate (+)-Camphoric Acid (+)-10-Camphorsulfonic Acid (-)-10-Camphorsulfonic Acid (+)-10-Camphorsulfonyl Chloride (-)-10-Camphorsulfonyl Chloride (+)-trans-1,2-Cyclohexanedicarboxylic Anhydride
Unit Size 5g 5g 25g
100mg
1g 100mg 25g 25g 25g 5g
25g 25g 25g 500g 5g 5g 5g 1g 500g 500g 500g 10g 25g 100mg
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Optical Resolution
Product No. Product Name C1418 D2636 D1386 D1911 D2645 D1398 D3826 D1354 D3492 D1853 D1417 D1387 G0057 G0059 M0021 M0022 M0662 M0661 M1221 M0990 M1021 I0334 I0335 M1622 M0824 I0336 I0398 P1354 P0573 Q0009 T0026 T0025 T1702 T1163
Unit Size
(-)-trans-1,2-Cyclohexanedicarboxylic Anhydride (+)-Diacetyl-D-tartaric Acid (-)-Diacetyl-L-tartaric Acid (+)-Diacetyl-L-tartaric Anhydride (-)-Diacetyl-D-tartaric Anhydride (+)-Dibenzoyl-D-tartaric Acid Monohydrate (+)-Dibenzoyl-D-tartaric Acid (-)-Dibenzoyl-L-tartaric Acid Monohydrate (-)-Dibenzoyl-L-tartaric Acid (R)-(-)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine (+)-Di-p-toluoyl-D-tartaric Acid (-)-Di-p-toluoyl-L-tartaric Acid D-Glutamic Acid L-Glutamic Acid D-(+)-Malic Acid L-(-)-Malic Acid D-(-)-Mandelic Acid L-(+)-Mandelic Acid (+)-Menthyl Chloroformate (-)-Menthyl Chloroformate (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid (R)-(+)-α-Methylbenzyl Isocyanate (S)-(-)-α-Methylbenzyl Isocyanate (R)-(+)-N-(α-Methylbenzyl)phthalamic Acid (S)-(-)-N-(α-Methylbenzyl)phthalamic Acid (R)-(-)-1-(1-Naphthyl)ethyl Isocyanate (S)-(+)-1-(1-Naphthyl)ethyl Isocyanate D-Pyroglutamic Acid L-Pyroglutamic Acid D-(-)-Quinic Acid D-(-)-Tartaric Acid L-(+)-Tartaric Acid (2R,3R)-Tartranilic Acid (+)-α-(2,4,5,7-Tetranitro-9-fluorenylideneaminoxy)propionic Acid
A1454
1g
25g 25g 1g
O
CH3 C O
A2128 O
C OH
O
CH3 C O
O
C OH
for Resolution of Alcohols & Thiols
A1984
B3296
CH2 CH CH2
B3549
B1219
N
O S
CH3
N N
S
CH3
CH3 COCl O
CH3
O
CH3
CH3 O
C1308 CH3 CH2SO2Cl
CH3
CH3
CH3
CH3 CH3
CH3
CH3
N CH3
C0998
B1220
CH3
CH2 CH CH2
C1022
5g 25g 25g 25g 25g 1g 25g 25g 25g 25g 5g 25g 25g 25g 5ml 5ml 25g 5g 1g
1g 1g 5g 25g
A1453 O
100mg 5g 25g 25g 25g 500g 250g 500g 250g 5g 250g 250g 250g 500g 25g 500g 500g 250g 25ml 25ml 500g 25g 5g 5g 1g 5g 5g 25g 500g 25g 500g 500g 5g 1g
CH3 ClSO2CH2
O
O
C1417 CH3
O
O
O
O
CH3
C1418 H
O
H
O
O H
O
O O
H
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
O
65
Optical Resolution
M0573
M0571
M1221
OCH2 C Cl
OCH2 C OH CH3
CH3
I0335
CH3
CH3
N0581
I0334 CH3
O
O
CH3
M0990 CH3
CH3
CH3
CH3
O
O
O C Cl
O C Cl
CH3
CH3
I0336
NCO
CH3
I0398
N0582
O
CH3
NCO
CH3
Cl HN
T1444
NCO
CH3
NCO
O Cl
SO2
HN
SO2
NO2
T2223 O HN
N
Cl HN
Ph
CH3 N
O
i
SO2
Si
tBu
Ph
SO2 iPr
Pr
CH3 iPr
Product No. Product Name A1454 A1453 A2128 A1984 B3296 B3549 B1219 B1220 C1022 C0998 C1308 C1417 C1418 M0573 M0571 M1221 M0990 I0334 I0335 N0581 I0336 I0398 N0582 T1444 T2223
(+)-O-Acetyl-L-mandelic Acid (-)-O-Acetyl-D-mandelic Acid (R)-5-Allyl-2-oxabicyclo[3.3.0]oct-8-ene (S)-5-Allyl-2-oxabicyclo[3.3.0]oct-8-ene (+)-Benzotetramisole (-)-Benzotetramisole Bis[(2R,3aS,4R,7aS)-octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl] Ether Bis[(2S,3aR,4S,7aR)-octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl] Ether (-)-Camphanic Chloride (+)-10-Camphorsulfonyl Chloride (-)-10-Camphorsulfonyl Chloride (+)-trans-1,2-Cyclohexanedicarboxylic Anhydride (-)-trans-1,2-Cyclohexanedicarboxylic Anhydride (-)-Menthoxyacetic Acid (-)-Menthoxyacetyl Chloride (+)-Menthyl Chloroformate (-)-Menthyl Chloroformate (R)-(+)-α-Methylbenzyl Isocyanate (S)-(-)-α-Methylbenzyl Isocyanate N-(1-Naphthalenesulfonyl)-L-phenylalanyl Chloride (R)-(-)-1-(1-Naphthyl)ethyl Isocyanate (S)-(+)-1-(1-Naphthyl)ethyl Isocyanate N-(4-Nitrophenylsulfonyl)-L-phenylalanyl Chloride N-(p-Toluenesulfonyl)-L-phenylalanyl Chloride Nα-(2,4,6-Triisopropylbenzenesulfonyl)-O-(tert-butyldiphenylsilyl)-π-methyl-L-histidinol
Unit Size 5g 5g 1g 200mg 100mg 100mg 1g 5g 5g
5ml
1g
5ml 5ml 5g 1g 1g 1g
25g 25g 5g 1g 1g 1g 1g 1g 25g 10g 25g 100mg 100mg 25ml 10g 25ml 25ml 25g 5g 5g 5g 5g 5g 5g 100mg
References 1) S. Hashimoto, S. Kase, A. Suzuki, Y. Yanagiya, S. Ikegami, . 1991, , 833; Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 04 273835, 1992. 2) K. Ishihara, Y. Kosugi, M. Akakura, . 2004, , 12212. 3) V. B. Birman, X. Li, . 2006, , 1351. 4) I. Shiina, K. Nakata, . 2007, 48, 8314; I. Shiina, K. Nakata, Y. Onda, . 2008, 5887.
66
Availability, price or specification of the listed products are subject to change without prior notice.
Enantiomer Excess & Absolute Configuration Determination
Enantiomer Excess & Absolute Configuration Determination Most biologically active compounds including pharmaceuticals have chiral molecular structures with one or more stereogenic centers. The absolute configuration of pharmaceuticals is very important for biological activity. Generally one enantiomer has medicinal activity while the other enantiomer has no activity. In some cases the opposite enantiomer gives rise to adverse and harmful effects. For this reason it is of great significance to obtain enantiopure compounds and to develop chiral auxiliaries for the determination of their absolute configurations and enantiomeric excess. Various kinds of reagents have been developed to determine their absolute configurations and enantiomeric excess by NMR1), HPLC2) and CD exciton chirality method3). A chiral shift reagent, Chirabite-AR (1), developed by Ema . is also one of the such reagents, and the optical purity can be easily measured using NMR.4) HN O
N
O HN
O
NO2
O HN N
O
O
HN
C2184 Chirabite-AR 1 Chirabite-AR (1) is a macrocyclic compound and has a very unique cavity where the hydrogen-bond donor and acceptor sites are well organized to enable the binding of a wide range of compounds as guest molecules. The incorporated guest molecules experience a strong anisotropic ring-current effect arising from the BINOL moiety, which is a chiral source, resulting in the chemical-shift nonequivalence between the two enantiomers.
(S)
(R)(S) (R)(S) (R)(R)(S)(S)
(R)
HO CO2H
5.1
5.0
4.9
S O
7
6.5
2.5
2
Chirabite-AR (7mg) in CDCl3 at 22℃ When conventional europium complexes are used on high-field NMR spectrometers, which are widely spread nowadays, signal broadening occurs, and as a result, satisfactory NMR spectra cannot be obtained. Because 1 contains no paramagnetic metals, which cause signal broadening, it can be used for both high- and low-field NMR spectrometers. Using 1, therefore, the enantiomeric purities of various compounds such as carboxylic acids, oxazolidinones, carbonates, lactones, alcohols, sulfoxides, sulfoximines, sulfinamides, isocyanates and epoxides can be determined. Moreover, a protocol for its determination is extremely easy; NMR spectra showing chemical-shift nonequivalences can be obtained just by adding 1 to the NMR tube containing a target sample in CDCl3. The reagent 1 is characterized by its facile use, versatility, and applicability to the low- and high-field NMR spectrometers. Thus, 1 has been shown to possess a highly effective capacity superior to that of the conventional chiral shift reagents.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
67
Enantiomer Excess & Absolute Configuration Determination
A1657
A1658
B1720
O O
O O
C OH
C OH
O N
for NMR
N
O
B1721
B1143
O
CH2
O
Si CH2 C OH
B1161
O
O
P OH
O
CH3
B1343
P OH
OH
OH
O
CH3
CH3
CH3
CH3
OH
OH
CH3
C1021
Si CH2 C OH
O
B1144
O
CH2
C2184
D2459
D2460
D1852 NO2
CH3 CO2H O
CH3
CH3
N H
O
N
N H
N
H N
H N
O
O
D1853
NHCH3
NHCH3
NHCH3
NHCH3
CH3
NH
C
NO2
O
O
O
O
O
D2176
D2175
M0662
NO2
M0661
O
O
O
C OH
NO2
NH2
NH2
HO
HO
C OH
C OH
HN C NH2
O
NH2
NO2
M1366
M1367
M0830
CH3
CH3
C OH
I0334
C OH
CH3O
O
O
C OH
CH3O
C OH
M0831 CH3
NCO
M0832
NCO
CF3
N0713 O
C Cl
CF3
O
C OH
C Cl
N0481 CH3
C OH
CF3 CH3O
N0482 O
OCH3
O
C OH
CH3O
N0714
CF3
O
O
C OH
O
O
O
M1103
O CH3O
M1104
CF3 CH3O
I0335
CF3
M1339
O
CH3O
CH3O
CH3
M0829
O
O
CH3
NH2
NH2
CH3O N
N
O
I0336
I0398 CH3
68
O
NCO
P0794 CH3
NCO
P0793 CH3
NH2
P1219 CH3
NH2
Availability, price or specification of the listed products are subject to change without prior notice.
O CH3
C OH
Enantiomer Excess & Absolute Configuration Determination
P1220
S0473
S0474
T1520
O CH3
C OH
O Na
O
O Sm3
O O
N
O
CH3
O N
O O
. xH2O
Na
HO
O Sm3
O O
N
O
CH3
T1521 CF3
HO
N
O O
Product No. Product Name A1657 A1658 B1720 B1721 B1143 B1144 B1161 B1343 C1021 C2184 D2459 D2460 D1852 D1853 D2176 D2175 M0662 M0661 M1366 M1367 M0830 M0829 M1339 I0334 I0335 M0831 M0832 M1103 M1104 N0713 N0714 N0482 N0481 I0336 I0398 P0794 P0793 P1219 P1220 S0473 S0474 T1520 T1521
CF3
O
Unit Size
(1R,2R)-2-(Anthracene-2,3-dicarboximido)cyclohexanecarboxylic Acid (1S,2S)-2-(Anthracene-2,3-dicarboximido)cyclohexanecarboxylic Acid (+)-Benzylmethylphenylsilylacetic Acid (-)-Benzylmethylphenylsilylacetic Acid (R)-(-)-1,1'-Binaphthyl-2,2'-diyl Hydrogen Phosphate (S)-(+)-1,1'-Binaphthyl-2,2'-diyl Hydrogen Phosphate (R,R)-(-)-2,3-Butanediol (S,S)-(+)-2,3-Butanediol (-)-Camphanic Acid Chirabite-AR (1R,2R)-(-)-N,N '-Dimethylcyclohexane-1,2-diamine (1S,2S)-(+)-N,N '-Dimethylcyclohexane-1,2-diamine (R)-(-)-N-(3,5-Dinitrobenzoyl)-α-phenylethylamine (R)-(-)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine (1R,2R)-(+)-1,2-Diphenylethylenediamine (1S,2S)-(-)-1,2-Diphenylethylenediamine D-(-)-Mandelic Acid L-(+)-Mandelic Acid (R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid (S)-(+)-2-Methoxy-2-(1-naphthyl)propionic Acid (R)-(-)-α-Methoxyphenylacetic Acid (S)-(+)-α-Methoxyphenylacetic Acid (+)-α-Methoxy-α-(trifluoromethyl)phenylacetic Anhydride (R)-(+)-α-Methylbenzyl Isocyanate (S)-(-)-α-Methylbenzyl Isocyanate (+)-MTPA (-)-MTPA (+)-MTPA-Cl (-)-MTPA-Cl (1R,2R)-2-(Naphthalene-2,3-dicarboximido)cyclohexanecarboxylic Acid (1S,2S)-2-(Naphthalene-2,3-dicarboximido)cyclohexanecarboxylic Acid (R)-(+)-1-(1-Naphthyl)ethylamine (S)-(-)-1-(1-Naphthyl)ethylamine (R)-(-)-1-(1-Naphthyl)ethyl Isocyanate (S)-(+)-1-(1-Naphthyl)ethyl Isocyanate (R)-(+)-1-Phenylethylamine (S)-(-)-1-Phenylethylamine (R)-(-)-2-Phenylpropionic Acid (S)-(+)-2-Phenylpropionic Acid Sodium [(R)-1,2-Diaminopropane-N,N,N ',N '-tetraacetato]samarate(III) Hydrate Sodium [(S)-1,2-Diaminopropane-N,N,N ',N '-tetraacetato]samarate(III) (R)-(-)-2,2,2-Trifluoro-1-(9-anthryl)ethanol (S)-(+)-2,2,2-Trifluoro-1-(9-anthryl)ethanol
A1657
100mg
100mg
100mg 100mg 100mg 100mg 5g 1g 5g 1g 5g 100mg 1g 5g 1g 5g 5g 5g 500g 250g 100mg 100mg 5g 5g 100mg 25g 5g 5g 5g 1g 1g 100mg 100mg 5g 5g 5g 5g 500ml 500ml 5g 5g 100mg 100mg 1g 1g
1g 100mg 1g 100mg 1g 100mg 1g 1g 1g 1g 25g 25g
100mg
1g 1g
1g
5g 1g 1g 1g 100mg 100mg
1g 1g 1g 1g 25ml 25ml 1g 1g
100mg 100mg
A1658
A5561 NH2
O O
for HPLC
N O
C OH
O O
C OH
N N
N O
SO2N
O N CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
CH3
69
Enantiomer Excess & Absolute Configuration Determination
A5560
A5565
A5564
NH2
A5568
N
N
O N CH3 SO2N CH3
SO2N
D2259
N
C Cl
N
O N CH3
O N CH3 SO2N CH3
CH3
A5524
A5523 O
C NH2
C NH2
NH
iPrCH 2
N0713 CH3
N0714
I0336
O
NCO
O
O O
C OH
N
A5563
A5566 O
NCO
N
N
O
N
A5577
A5578
N N
N
O
N
NO2
N
O
N
NO2
A5515
O
AcO AcO
OAc O NCS
BzO BzO
AcO
OBz O NCS BzO
NO2
Unit Size
(1R,2R)-2-(Anthracene-2,3-dicarboximido)cyclohexanecarboxylic Acid (1S,2S)-2-(Anthracene-2,3-dicarboximido)cyclohexanecarboxylic Acid (R)-(-)-DBD-APy [=(R)-(-)-4-(N,N-Dimethylaminosulfonyl)-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole] (S)-(+)-DBD-APy [=(S)-(+)-4-(N,N-Dimethylaminosulfonyl)-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole] (R)-(+)-DBD-Pro-COCl [=(R)-(+)-4-(N,N-Dimethylaminosulfonyl)-7-(2-chloroformylpyrrolidin-1-yl)-
100mg 100mg 100mg 100mg
2,1,3-benzoxadiazole]
100mg
A5564
(S)-(-)-DBD-Pro-COCl [=(S)-(-)-4-(N,N-Dimethylaminosulfonyl)-7-(2-chloroformylpyrrolidin-1-yl)-
A5568
(R)-(-)-DBD-Py-NCS [=(R)-(-)-4-(N,N-Dimethylaminosulfonyl)-7-(3-isothiocyanatopyrrolidin-1-yl)-
A5569
(S)-(+)-DBD-Py-NCS [=(S)-(+)-4-(N,N-Dimethylaminosulfonyl)-7-(3-isothiocyanatopyrrolidin-1-yl)-
D2259 A5524 A5523 M1366 M1367 I0334 I0335 N0713 N0714 I0336 I0398 A5563
Nα-(5-Fluoro-2,4-dinitrophenyl)-L-alaninamide Nα-(5-Fluoro-2,4-dinitrophenyl)-D-leucinamide Nα-(5-Fluoro-2,4-dinitrophenyl)-L-leucinamide (R)-(-)-2-Methoxy-2-(1-naphthyl)propionic Acid (S)-(+)-2-Methoxy-2-(1-naphthyl)propionic Acid (R)-(+)-α-Methylbenzyl Isocyanate (S)-(-)-α-Methylbenzyl Isocyanate (1R,2R)-2-(Naphthalene-2,3-dicarboximido)cyclohexanecarboxylic Acid (1S,2S)-2-(Naphthalene-2,3-dicarboximido)cyclohexanecarboxylic Acid (R)-(-)-1-(1-Naphthyl)ethyl Isocyanate (S)-(+)-1-(1-Naphthyl)ethyl Isocyanate (R)-(-)-NBD-APy [=(R)-(-)-4-Nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole]
100mg
2,1,3-benzoxadiazole]
100mg
2,1,3-benzoxadiazole] 2,1,3-benzoxadiazole]
70
O
NO2
Product No. Product Name A1657 A1658 A5561 A5560 A5565
C Cl
NCS
N
N
N
A5514
NCS
N
N
O
NO2
NO2
O
C Cl
N
N N
A5567
NH2
N
NCO
O
A5562 NH2
CH3
C OH
N
O
CH3
C OH
CH3O
NO2
I0335
I0398
O CH3
C OH
F NO2
NCO
CH3
CH3O
NO2
F NO2
I0334
O N CH3 SO2N CH3
M1367 CH3
NO2
F
N
O N CH3
O
NH
NH NO2
N N
M1366
O
C NH2
iPrCH 2
N C S
N
SO2N
O CH3
CH3
C Cl
N
N
A5569 N C S
O
O
Availability, price or specification of the listed products are subject to change without prior notice.
100mg 100mg
1g
5g 1g
1g 1g
100mg 1g 1g 100mg 100mg 100mg 25g 5g 100mg 100mg 5g 5g 100mg
Enantiomer Excess & Absolute Configuration Determination
Product No. Product Name A5562 A5566 A5567 A5577 A5578 A5514 A5515
Unit Size
(S)-(+)-NBD-APy [=(S)-(+)-4-Nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole] (R)-(+)-NBD-Pro-COCl [=(R)-(+)-4-Nitro-7-(2-chloroformylpyrrolidin-1-yl)-2,1,3-benzoxadiazole] (S)-(-)-NBD-Pro-COCl [=(S)-(-)-4-Nitro-7-(2-chloroformylpyrrolidin-1-yl)-2,1,3-benzoxadiazole] (R)-(-)-NBD-Py-NCS [=(R)-(-)-4-(3-Isothiocyanatopyrrolidin-1-yl)-7-nitro-2,1,3-benzoxadiazole] (S)-(+)-NBD-Py-NCS [=(S)-(+)-4-(3-Isothiocyanatopyrrolidin-1-yl)-7-nitro-2,1,3-benzoxadiazole] 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl Isothiocyanate 2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranosyl Isothiocyanate
C1766
C1682 CH3
O HO C
for X-ray Crystallography
CH3
CH3
100mg 100mg 100mg 100mg 100mg 100mg 1g 100mg 1g
C1767
CH3
O
O
C
C N
CH3
O
O
HO C
C OH
C N
N S O
O
O
S
Cl
S O
CH3
O
O
Cl
O
C1683 CH3
CH3 O O
C OH
C N S O
Cl
O Cl
Product No. Product Name
Unit Size
N-(2-Carboxybenzoyl)-(+)-10,2-camphorsultam N-(2-Carboxybenzoyl)-(-)-10,2-camphorsultam N-(2-Carboxy-4,5-dichlorobenzoyl)-(+)-10,2-camphorsultam N-(2-Carboxy-4,5-dichlorobenzoyl)-(-)-10,2-camphorsultam
C1766 C1682 C1767 C1683
500mg 500mg 500mg 500mg
A0482
A1150 COOH O C OH
for Exciton Chirality CD Method
A0690
B0062
for Hydroxy Groups B0105
OCH3
B0553
O
O
O
C OH
C OH
C Cl
B0558 O
COOH
C Cl
Br
C0134
C0141
C0445
O
O
C OH
C Cl
Cl
Cl
C1182
Br
D0724 O
CN
CN
COOH
COCl
C OH
N
CH3 CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
71
Enantiomer Excess & Absolute Configuration Determination
M0721
M1338
M0576
N0025
N0048
O C Cl
O NH
O OH
C OCH3
N
O
O
N HN
OH
Cl
CH3O OCH3
N0156
N0176
P0961
O
O
C OH
C Cl
P1079
O
O
C OH
C Cl
NO2
NO2
Product No. Product Name A0482 A1150 A0690 B0062 B0105 B0553 B0558 C0134 C0141 C0445 C1182 D0724 M0721 M1338 M0576 N0025 N0048 N0156 N0176 P0961 P1079
Unit Size
p-Anisic Acid 2-Anthracenecarboxylic Acid 9-Anthracenecarboxylic Acid Benzoic Acid Zone Refined (number of passes:20) Benzoyl Chloride 4-Bromobenzoic Acid 4-Bromobenzoyl Chloride 4-Chlorobenzoic Acid 4-Chlorobenzoyl Chloride 4-Cyanobenzoic Acid 4-Cyanobenzoyl Chloride 4-Dimethylaminobenzoic Acid 4-Methoxybenzoyl Chloride 5-(4-Methoxycarbonylphenyl)-10,15,20-triphenylporphyrin 4-Methoxycinnamic Acid 2-Naphthoic Acid 2-Naphthoyl Chloride 4-Nitrobenzoic Acid 4-Nitrobenzoyl Chloride 4-Phenylbenzoic Acid 4-Phenylbenzoyl Chloride
D0648
D0645 D1495
25g 1g 5g
500g 5g 25g 1sample 25ml 500ml 25g 500g 25g 250g 25g 500g 25g 500g 5g 25g 250g 5g 25g 25g 500g 25g 500g 100mg 1g 25g 25g 25g 25g 500g 25g 500g 25g 500g 5g 25g
N0530
O
O
C H CH3
for Primary Amino Groups
CH3
N
O N
CH
CH
O
C H
CH3
O
CH3
Product No. Product Name D0645 D1495 D0648 N0530
Unit Size
4-Dimethylaminobenzaldehyde 4-Dimethylaminobenzaldehyde 4-Dimethylaminocinnamaldehyde 2,3-Naphthalenedicarboxylic Anhydride
B3515
A1371
72
N CH3CH2 CH3CH2
N Zn N
CH3
H2NCH2CH2NH C O C CH3
CH2 CH2CH3 CH2CH3
O
CH3
Boc
500g 500g 25g 250g
B2124 O
CH2CH3 N
B1185
CH2CH3
CH3CH2 CH3CH2
for Monoalcohols, Monoamines
25g 25g 5g 25g
H N
CH2NH
O
CH3
C OC CH3 CH3
OH
2
Availability, price or specification of the listed products are subject to change without prior notice.
O N
C OH
Enantiomer Excess & Absolute Configuration Determination
P1364
N N
N Zn N
O C
N N
(CH2)5
N Zn N
C O
Product No. Product Name B3515 A1371 B1185 B2124 P1364
Bis(Zinc Porphyrin) (ca. 5μmol/L in Dichloromethane) N-Boc-1,2-diaminoethane Boc-Gly-OH 4-[(tert-Butoxycarbonylamino)methyl]pyridine-2-carboxylic Acid Pentamethylene Bis[4-(10,15,20-triphenylporphin-5-yl)benzoate]dizinc(II)
Unit Size 1g
5ml 25ml 5g 25g 5g 25g 100mg 1g 10mg 100mg
References 1) J. A. Dale, H. S. Mosher, . 1973, , 512; I. Ohtani, T. Kusumi, Y. Kashman, H. Kakisawa, . 1991, , 4092; N. Harada, M. Watanabe, S. Kuwahara, A. Sugio, Y. Kasai, A. Ichikawa, : 2000, , 1249; Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 2001 261613, 2001. 2002, 2) T. Toyo’oka, , 25; K. Fujii, Y. Ikai, H. Oka, M. Suzuki, K. Harada, 1997, , 5146; K. Fujii, Y. Ikai, T. Mayumi, H. Oka, M. Suzuki, K. Harada, , 3346. 2001, 3) T. Kurtan, N. Nesnas, F. E. Koehn, Y.-Q. Li, K. Nakanishi, N. Berova, , 5974. 2006, , 3773; T. Ema, D. Tanida, T. Sakai, 2007, 4) T. Ema, D. Tanida, T. Sakai,
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
1997,
, 10591.
73
Chiral Columns for HPLC
Chiral Columns for HPLC ●Chiral Columns“TCI Chiral” New type of chiral separation with synthetic organic polymer phase systems “ - TCI Chiral” 1. A unique new stationary phase Polymaleimide helical polymer bearing chiral side groups coated on silica gel 2. Suitable for separation of a wide range of compounds Carbonyls (Ketones, Esters, Carboxylic acids, -Protected amino acids), Alcohols and others 3. Applicable to both normal and reversed phase modes 4. High column load capacity 5. Superior column longevity Maximum pressure: 2900 psi (20 MPa) 6. High throughput analysis 7. Affordable prices
Product Line Column
Retention Power (Normal Phase)
TCI Chiral MB-S
High
TCI Chiral BP-S
Medium
TCI Chiral CH-S
Weak
Analytes Low Polarity
Carbonyls (Amides, Esters, Ketones, Lactones, Moderate Polarity Carboxylic acids, -Protected amino acids), Alcohols, Diols, Sulfonyls and others High Polarity
Normal and Reversed Phase Applications ＜Normal Phase＞ n-Hexane / 2-Propanol = 70 / 30（TCI Chiral MB-S） 90 / 10（TCI Chiral BP-S and TCI Chiral CH-S）
TCI Chiral MB-S（3μm） TCI Chiral BP-S（3μm） TCI Chiral CH-S（3μm）
Column Size Detection Flow Rate Temperature Sample
： ： ： ：
4.6 mm I.D. × 250 mm UV 210 nm 1.0 mL/min 40 ℃
： Butyl Lactate
0.0
2.5
5.0
7.5
Time(min)
0.0
2.5
5.0
7.5
Time(min)
0.0
2.5
5.0
7.5
Time(min)
O O OH
＜Reversed Phase＞ Acetonitrile / Water = 10 / 90
TCI Chiral MB-S（5μm） TCI Chiral BP-S（5μm） TCI Chiral CH-S（5μm）
0
74
5
10
15
Time(min)
0
5
10
15
Time(min)
Availability, price or specification of the listed products are subject to change without prior notice.
0
5
10
15
Time(min)
Chiral Columns for HPLC
Column Particle Size
TCI Chiral MB-S
TCI Chiral BP-S
TCI Chiral CH-S
3μm
5μm
3μm
5μm
3μm
5μm
2.0mmI.D.×50mm
S3816
S3846
S3826
S3856
S3836
S3866
2.0mmI.D.×150mm
S3812
S3842
S3822
S3852
S3832
S3862
2.0mmI.D.×250mm
S3813
S3843
S3823
S3853
S3833
S3863
4.6mmI.D.×50mm
S3815
S3845
S3825
S3855
S3835
S3865
4.6mmI.D.×150mm
S3810
S3840
S3820
S3850
S3830
S3860
4.6mmI.D.×250mm
S3811
S3841
S3821
S3851
S3831
S3861
10.0mmI.D.×250mm
−
S3870
−
S3880
−
S3890
20.0mmI.D.×250mm
−
S3871
−
S3881
−
S3891
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
75
Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds
Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds Introduction of fluorine into a certain position of bioactive compound such as a pharmaceutical and an agricultural chemical may remarkably reduce the toxicity of the compound, or improve the efficiency of medicine. This is due to the mimic and blocking effect characterized by fluorine. Many compounds, such as 5-fluorouracil, have been reported as success case. Attempts to efficiently synthesize fluorine-containing compounds are performed in many fields. Methods to introduce fluorine into a certain position through the use of fluorinating agents or the use of fluorinecontaining building blocks have been reported. 4-Butyl-2,6-dimethylphenylsulfur trifluoride (1) (FLUOLEAD™), which was first reported by Umemoto ., is a novel nucleophilic fluorinating reagent. Differing from other existing fluorinating reagents, such as DAST, 1 is a crystalline solid with high thermal stability and has less fuming character, which makes it easier to handle. 1 fluorinates a hydroxy or carbonyl group to afford the corresponding fluorinated compounds in good yields.1) Furthermore, 1 even fluorinates thioketones or thioesters. CH3 CH3 CH3
SF3 CH3
S
CH3 OCH3
CF2OCH3
1 (1.5 eq.) CH2Cl2, rt, 26 h
Y. 75%
Triethyl 2-fluoro-2-phosphonoacetate (2) has increasingly been utilized as a useful bifunctional fluorine-containing intermediate.2) This compound is very useful in the generation of physiologically active compounds because it can generate α-fluoro-α,β-unsaturated ester from the reaction with carbonyl compounds in the presence of a base. A subsequent reduction of the above ester leads to the corresponding aldehyde or alcohol. As examples, vitamin A derivatives,3) pheromone of insect origin,4) synthesis of Pyrethroide5) having insecticidal efficacy, etc., can be given.
Me
EtO
Me
Me
CHO Me
EtO
O
F
P CH
CO2Et ,BuLi
Me
Me
Me
Me
Me
Me
F
2 -78 °C ~ 0 °C
Me
CO2Et
CO2Et + Me
F
Y. 95% (2E : 2Z = 5 : 2)
[(Oxido)phenyl(trifluoromethyl)-λ4-sulfanylidene]dimethylammonium tetrafluoroborate (3) is a novel electrophilic trifluoromethylating reagent which was developed by Shibata . 3 trifluoromethylates various substrates under mild conditions to afford the corresponding trifluoromethylated compounds in high yields.6) BF4+ S N(CH3)2
O
CF3 O
3 (1.5 eq.) DBU (1.2 eq.)
C OR O
CH2Cl2, rt, 1 h
O CF3 C OR O R = CH3; Y. 93% R = Bn; Y. 90%
76
Availability, price or specification of the listed products are subject to change without prior notice.
Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds
F0342
Cl
Electrophilic Fluorinating Reagents F0358
Cl
CF3SO3
N
O O S N S O F O
N
F
F 2BF4
F0334
F0343
F0327
F 2BF4
N
Cl
N
CH2Cl
BF4
Cl
B2F7
N
N
F
F0346
N
BF4
F
CF3SO3
N F
F
F0328 CH3
CH3 BF4
CH3
N
F0335
F
F0344
N
D3812
N
CH3
CF3SO3 CH3
N
CH3
F
F
Product No. Product Name F0342 D3812 F0335 F0358 F0344 F0334 F0343 F0327 F0346 F0328
Unit Size
2,6-Dichloro-1-fluoropyridinium Trifluoromethanesulfonate 1,1'-Difluoro-2,2'-bipyridinium Bis(tetrafluoroborate) N-Fluorobenzenesulfonimide N-Fluoro-N '-(chloromethyl)triethylenediamine Bis(tetrafluoroborate) 1-Fluoro-2,6-dichloropyridinium Tetrafluoroborate 1-Fluoropyridinium Pyridine Heptafluorodiborate 1-Fluoropyridinium Tetrafluoroborate 1-Fluoropyridinium Trifluoromethanesulfonate 1-Fluoro-2,4,6-trimethylpyridinium Tetrafluoroborate 1-Fluoro-2,4,6-trimethylpyridinium Trifluoromethanesulfonate
B2440
5g
25g 1g 25g 25g 25g 5g 25g 25g 5g 25g
5g 5g 5g 5g 5g 5g
B3664
D1868 SF3
CH3OCH2CH2
Nucleophilic Fluorinating Reagents D2831
N
CH3 F
Et
T1909
F Ph
Bu
. (HF)x
F
Bu
F
Ph
N Bu Bu
Bu
HF2
T2027
Bu
H2F3
N Bu Bu
T1339 T1338 T1037 T1125
Bu
Ph
Sn
Bu
N
O
T1635
Ph
F
F
T1295
SF3
F Bu4N
CH3 C CH3
CF3
F Ph Si
Et
N
T1592
Ph
N S
P0999
F
N F
CH3
F
Et
F
M1573 Et
F
CH3
F
CH3
H0598 N
Bu4N
CH3OCH2CH2
CH3
F N S
N Bu
F
(CH3CH2)4NF
. 4HF
Bu
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
77
Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds
T2026
T2023
(CH3CH2)4NF
. 3HF
(CH3CH2)3N
T2022
. 5HF
(CH3CH2)3N
. 3HF
Product No. Product Name B2440 B3664 D1868 D2831 H0598 M1573 P0999 T1295 T1909 T1592 T1635 T1339 T1338 T1125 T1037 T2027 T2026 T2023 T2022
Unit Size
Bis(2-methoxyethyl)aminosulfur Trifluoride 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride (Diethylamino)sulfur Trifluoride 2,2-Difluoro-1,3-dimethylimidazolidine Ishikawa's Reagent Morpholinosulfur Trifluoride Pyridinium Poly(hydrogenfluoride) Tetrabutylammonium Bifluoride Tetrabutylammonium Difluorotriphenylsilicate Tetrabutylammonium Difluorotriphenylstannate Tetrabutylammonium Dihydrogen Trifluoride Tetrabutylammonium Fluoride (70-75% in Water) Tetrabutylammonium Fluoride (1mol/L in Tetrahydrofuran) Tetrabutylammonium Fluoride (1mol/L in Tetrahydrofuran) Tetrabutylammonium Fluoride Hydrate Tetraethylammonium Fluoride Tetrahydrofluoride Tetraethylammonium Fluoride Trihydrofluoride Triethylamine Pentahydrofluoride Triethylamine Trihydrofluoride
5g 5g
25ml
O0367
T2624
S N
Trifluoromethylating Reagents
CF3
CH3 CH3
I
O
BF4
CH3 CF3
CH3
Unit Size
P1080
P1659 O
CF3(CF2)5
I
O S CF3
CF3 CF3
I
OSO2CF3
O
O S CF3 O
78
5g
1g 1g 25g
O CF
O I
200mg
P1081
P1082
CF3CF2CF2
Si CH3 CH3
[(Oxido)phenyl(trifluoromethyl)-λ4-sulfanylidene]dimethylammonium Tetrafluoroborate 1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole (Trifluoromethyl)trimethylsilane
Fits Reagents
25g 1g 25g 5g 5g 1g 5g 25g 100ml 25ml 25g
CH3
Product No. Product Name O0367 T2624 T1570
25g
T1570
CF3
O
25g 5g 100g 10g 500g 5g 100g 25g 25g 5g 25g 500g 500ml 100ml 250g 10g 10g 10g 10g
Availability, price or specification of the listed products are subject to change without prior notice.
CF3(CF2)7
I
O S CF3 O
Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds
Product No. Product Name P1080 P1659 P1081 P1082
Unit Size
(Perfluorohexyl)phenyliodonium Trifluoromethanesulfonate (Perfluoroisopropyl)phenyliodonium Trifluoromethanesulfonate (Perfluoro-n-octyl)phenyliodonium Trifluoromethanesulfonate (Perfluoropropyl)phenyliodonium Trifluoromethanesulfonate
1g
B3498
5g 500mg 1g 1g
B1801 O C H Br
Br
Aliphatic & Aromatic Compounds
Fluorinated Building Blocks
C0990
C1503
CH2 CF3
F
C2381
F0283
D2523
O O
O
F F
F
OH
F
Cl
O
Cl
O
C H F
O
Cl
CH3
F
Cl
CH3
O
O
O
F
O
F
OH
CH3
F
F
D1423
D2525
D2524 CH3 C H N CH
O F
OH
C1467
Cl
CH3
E0547
O
CH3
F0030
OH O
CH3
F
F0341
O
CH3
F0518
F
P1894
C0991 F
F
CF3
C O
F F
F
F
CH3
Cl Cl
O
CF3
O
O
O
CH3
O
CF3
OCH3
F0340
CH3CH2O
F
CH3
S CF2 C OCH3
Cl ONa
Cl
O
T1032
O F
O
O
Cl
F0042
O
F
O F
T1245
O OCH3
O
N CH3 F
F0311
F
O
CH3
T0810
CF3
F
O Si CH3
CH3
O CH3
C1586
CH2 C
CH3 O
F
O
CH3
D2782
T0432
F
SO2CH2F
CH3
O F
F
Br
CH3 O
F
CH3
Br
Br
O
O O
O
F
O
F Br
O
D2498
E0663
O
O F
O
F
Cl
B1673
F C H
N CH
F
O O
F
C
D2530
O
CH3
CH3
F
C1458
F
H
F C H
F
F
B1463
CCl3CF3
CH3CH2O
O
O
P
OCH2CH3 F
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
79
Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds
T0791
T0433
OH O
CF3
O CF3
CH3
T1604
O
CF3
C N
O
T1516
O CH3
CF3CH2OH
CF3
O S OCH2CF3
CH3
O
T2547 O
OCH3
S OCH2CF3 O
T1512
Cl
S OCH2CF3
M1193
O
T2638
O CF3
T0435
CH2
Cl OH
CF3
C N
CF3
Product No. Product Name B3498 B1801 C0990 C1503 C2381 F0283 D2523 D1423 D2525 D2524 B1463 B1673 C1458 C1467 D2530 D2498 D2782 E0547 F0030 E0663 T0432 T0810 F0341 F0518 C1586 F0311 T1245 P1894 C0991 F0042
2-Bromo-4-fluorobenzaldehyde 2-Bromo-3,3,3-trifluoro-1-propene (stabilized with Copper chip) Chlorodifluoroacetic Acid Chlorodifluoroacetic Anhydride 2-Chloro-5-fluorobenzaldehyde Diethyl Fluoromalonate Difluoroacetaldehyde Ethyl Hemiacetal Difluoroacetic Acid (R)-N-(2,2-Difluoroethylidene)-1-phenylethylamine (S)-N-(2,2-Difluoroethylidene)-1-phenylethylamine Ethyl Bromodifluoroacetate Ethyl Bromofluoroacetate Ethyl Chlorodifluoroacetate Ethyl Chlorofluoroacetate Ethyl Dibromofluoroacetate Ethyl Difluoroacetate Ethyl 3-(Dimethylamino)-3-ethoxy-2,2-difluoropropionate Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate Ethyl Fluoroacetate Ethyl 2-Fluoropropionate Ethyl Trifluoroacetate Ethyl 4,4,4-Trifluoroacetoacetate Fluoromethyl Phenyl Sulfone (1-Fluorovinyl)methyldiphenylsilane Methyl Chlorodifluoroacetate Methyl Fluorosulfonyldifluoroacetate Methyl 4,4,4-Trifluoroacetoacetate Pentafluorophenyl Trifluoroacetate Sodium Chlorodifluoroacetate Trichlorofluoromethane (in cylinder without valve) [To use this product charged in cylinder,
T1032 F0340 T0791 T0433 T0435 M1193 T1516 T1604 T2638 T1512 T2547
1,1,1-Trichloro-2,2,2-trifluoroethane Triethyl 2-Fluoro-2-phosphonoacetate Trifluoroacetaldehyde Ethyl Hemiacetal (contains ca. 10% Ethanol) Trifluoroacetic Anhydride 2,2,2-Trifluoroethanol 2,2,2-Trifluoroethyl Methanesulfonate 2,2,2-Trifluoroethyl p-Toluenesulfonate 2,2,2-Trifluoroethyl Trifluoromethanesulfonate 2,2,2-Trifluoro-N-(4-methoxyphenyl)acetimidoyl Chloride 2-(Trifluoromethyl)acrylic Acid 2,2,2-Trifluoro-N-phenylacetimidoyl Chloride
Unit Size
1g
5g
5g 5g 25g 10g 5g 5g 5g 5g
25g 5g 25g 5g 5g 5g 1g 25ml 5g 25g 25g 1g 1g 5g 5g 5g 5g 25g
a valve is required which is sold separately (Product Code:V0030)]
80
Availability, price or specification of the listed products are subject to change without prior notice.
1g 20ml 25g 5g 25g 5g 5g
25g 25g 500g 25g 25g 25g 25g 25g 1g 1g 250g 25g 500g 25g 25g 25g 5g 1g 500ml 25g 500g 500g 5g 5g 25g 25g 25g 25g 500g 400g 25g 5g 10g 400ml 500g 25g 500g 25g 5g 25g 5g
Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds
A1993
A2125
A1664 NH2
N
Heterocyclic Compounds
F
B2799
F
S
NH2
F
F
N
NH2
B3244
A1546
N
N
OCH3
B2705
NH2
F
B3177
F
N N
Br
N
N
C2113
C2221
F
C2270
N N
F
D3614
N
O
O
C1666 F
N
N H
D3642
Cl
F
D3615
NH2 N
F
N
HO
O
O
F HO
OH
D2057
N N
F0656
Cl N
Cl
N
F
F
F0180
F
NH2
O
N
F
N
NH N
F0534
OCH2CH3
F0556
F
N N
N H
F0369
NH2
NH2 N
Cl
F0647
F
Cl
F
Cl
N
E0684
F Cl
F
F
D1741
Cl F
C OH
O
OH
D3374
N
N
O
Cl
F
OH
F
O
HN
N
O
. xH2O
F
N
D3317
F N
Cl
O
N
O
HO
Cl
D2610
NH2
C OH
C OC(CH3)3
F
N
F
N
C OC(CH3)3
C1549
F
F
O
C OH
Cl Cl
F
F O
Br
Br
N
B3178
F F
F
N
F
F
N
F
N HO
N
N
F
HO
S
O OH
F
O
N
O
OH
OH
OH
F0352
F0555
F0523
F0589
N H
F0693
F
N H
F0547 O C OH
N
F
N
O
F
N
OCH3
F
S
CH3
O
F0533
F
N
N H
O
F0420
NH
O
O N H
F
F0316
F
F0551
F
I F
N H
N H
CH3
N O
CH3
N
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
F
81
Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds
F0579
F0581
F0520
CH3
F
F
F0575
F
N
F0382
N
CH3
F0207
NH
HO C
N H
T1778
F
F N
F
F
N
82
F
N
T2061 F
F
F
F N H
. HCl
F F
F N
OH
Product No. Product Name A1993 A2125 A1664 A1546 B2799 B3244 B2705 B3177 B3178 C2113 C2221 C2270 C1549 C1666 D3614 D3642 D3615 D2610 D3317 D3374 D2057 D1741 E0684 F0647 F0656 F0180 F0534 F0556 F0369 F0352 F0555 F0523 F0589 F0551 F0693 F0547 F0316 F0420 F0533 F0579
CH3
. HCl N
T2342
OH
N
. H2O
O
F F
F
F0628
F
F O
N
CH3
O
C OH
F0038
N
F0217
O
F
F0519
F
CH3
N
N
F0300
2-Amino-6-fluorobenzothiazole 4-Amino-5-fluoro-2-methoxypyrimidine 2-Amino-5-fluoropyridine 4-Amino-2,3,5,6-tetrafluoropyridine 2-Bromo-5-fluoropyridine 3-Bromo-5-fluoropyridine 5-Bromo-2-fluoropyridine (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid (2S,4S)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid 5-Chloro-2,3-difluoropyridine 6-Chloro-2-fluoropurine 2-Chloro-5-fluoropyridine 3-Chloro-2,4,5,6-tetrafluoropyridine 5-Chloro-2,4,6-trifluoropyrimidine 2'-Deoxy-2'-fluorocytidine Hydrate 2'-Deoxy-5-fluorocytidine 2'-Deoxy-2'-fluorouridine 2,6-Dichloro-5-fluoronicotinic Acid 3,5-Dichloro-2-fluoropyridine 2,4-Dichloro-5-fluoropyrimidine 3,5-Dichloro-2,4,6-trifluoropyridine 2,6-Difluoropyridine 2-Ethoxy-5-fluoro-4-pyrimidinone 2-Fluoroadenine 2-Fluoroadenosine 2-Fluorobenzothiazole 5-Fluorocytidine 4-Fluoroindole 5-Fluoroindole 6-Fluoroindole 7-Fluoroindole 2-Fluoro-5-iodopyridine 5-Fluoroisatin 7-Fluoroisatin 2-Fluoroisonicotinic Acid 5-Fluoro-2-methoxy-4-pyrimidinone 5-Fluoro-2-methylbenzothiazole 5-Fluoro-2-methylbenzoxazole 2-Fluoro-3-methylpyridine 2-Fluoro-4-methylpyridine
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 5g 1g 5g 1g 5g 200mg 200mg 5g 1g 5g 5g 1g 1g 5g 1g 5g 5g 5g 5g 200mg 200mg 1g 1g 1g 1g 5g 5g 1g 5g 5g 1g 1g 5g
5g 25g 5g 1g 25g 5g 25g 1g 1g 25g 1g 5g 25g 25g 1g 5g 5g 25g 5g 25g 25g 25g 25g 1g 1g 1g 5g 1g 5g 5g 1g 5g 25g 25g 5g 25g 25g 5g 5g 25g
Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds
Product No. Product Name F0581 F0520 F0300 F0519 F0575 F0382 F0217 F0207 F0628 F0038 T1778 T2342 T2061
Unit Size
2-Fluoro-5-methylpyridine 2-Fluoro-6-methylpyridine 6-Fluoro-2-methylquinoline 7-Fluoro-2-methylquinoline 2-Fluoronicotinic Acid 5-Fluoroorotic Acid Monohydrate 2-Fluoropyridine 3-Fluoropyridine 4-Fluoropyridine Hydrochloride 5-Fluoro-8-quinolinol 2,3,5,6-Tetrafluoropyridine 3,3,4,4-Tetrafluoropyrrolidine Hydrochloride 3,5,6-Trifluoro-2-hydroxypyridine
1g 1g 1g 1g 100mg
B3165 OH OH CH3
H3C
HO H3C
HO
H3C O
N
O O
OH
E0786
H3C
O
N
F
C OH
N
N
CH3
HN
F0321
HO H3C
O
F
CH2CH2F
CH2CH3
NH2
CH3
F
O
CF3
N
H H
N
. 1 1/2H2O
CF3
N
N
N
F0691
OH CH3
O H3C
O
O
O
N
CH3
CF3
F0437
C OH
C OH
F
H
O
O
O
CH3
NH C N
N
OH
. HCl . H2O
N
E0762
H F
F0646
F
C OH
N
O
OH OH CH3
H3C
HO
O
OH
CH3CH2
F N
O
HN
H
D3773 O
HN
H F
D1961
F
O F
CH3
O
O
HN
HO
H
O OH CH3
H3C
H3C
F
D3579
O
H
O
O
C2227 O
O
D2235
5g 1g 1g 1g 1g 1g
100mg
B1837
Fluorinated Bioactive Compounds
5g 5g 5g 5g 5g 1g 25g 25g 5g 5g 5g 5g 5g
H
O
CHOCH2F
O
N H
F
F0635
F0151
F0636
F0371
O F
HO
N N H
O
HO H3C
CH C OH CH3
L0216
OH
N CH3
O
C OH
P1897
O
F
C OH
N
H
T2506
F
CH2CH3
O
F
O
F
N
O C OH
SO3H
C OH O N
. HCl
N
HN
CH3
O
O
F CH3
N
N
CH3 CH3
F
N0817
O
F O
H F
O O F
S O
O
OH
L0193
N
O
O
O H3C
F O
NH
O
F
HN
N
CH2CH3
HN
N
N
N
N
N CH3
.
F
HN O
F0525
O
O
F
N OH
CH3
NH2
. xH2O F
T2303
T2308 O H3C
HO H3C
O H3C
HO H3C
H F
O
OH OH OH
T2511
H
H
O
O
CF3
HN
CH3 HO
O
N
O F
O
O
OH CH3
H OH
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
83
Fluorinating Reagents, Building Blocks & Fluorinated Bioactive Compounds
Product No. Product Name B1837 B3165 C2227 D2235 D3579 D1961 D3773 E0762 E0786 F0646 F0437 F0321 F0691 F0635 F0151 F0636 F0371 F0525 L0193 L0216 N0817 P1897 T2506 T2303 T2308 T2511
Betamethasone Betamethasone 21-Acetate Ciprofloxacin Hydrochloride Monohydrate 2'-Deoxy-5-fluorouridine 5'-Deoxy-5-fluorouridine Dexamethasone 1,1-Dimethyl-3-[3-(trifluoromethyl)phenyl]urea Enoxacin Sesquihydrate Enrofloxacin Fleroxacin Flunisolide 5-Fluorocytosine Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether 5-Fluoro-1-(tetrahydro-2-furfuryl)uracil 5-Fluorouracil 5-Fluorouridine Flurbiprofen Fluticasone Propionate Levofloxacin Lomefloxacin Hydrochloride Norfloxacin Paliperidone Tosufloxacin p-Toluenesulfonate Hydrate Triamcinolone Triamcinolone Acetonide Trifluorothymidine
Unit Size 1g 1g 5g 100mg 500mg 1g 5g 5g 5g 5g 1g
5g 5g 5g 1g 5g 5g 5g 5g 200mg 5g 1g 100mg
5g 5g 25g 1g 5g 1g 25g 25g 25g 25g 1g 25g 5g 25g 25g 5g 25g 100mg 25g 25g 25g 1g 25g 1g 5g 1g
References 1) T. Umemoto, R. P. Singh, Y. Xu, N. Saito, . 2010, , 18199. 1997, 2) M. Kikuchi, T. Onozawa, , 88. 3) R. S. H. Liu, H. Matsumoto, A. E. Asato, M. Denny, Y. Shichida, T. Yoshizawa, F. W. Dahlquist, , 7195; A. J. Lovey, B. A. Pawson, . 1982, , 71. 1984, 4) F. Camps, J. Coll, G. Fabrias, A. Guerrero, , 2871. 5) Ph. Coutrot, C. Grison, R. Sauvetre, . 1987, , 1. 6) S. Noritake, N. Shibata, S. Nakamura, T. Toru, M. Shiro, . 2008, 3465.
84
Availability, price or specification of the listed products are subject to change without prior notice.
. 1981,
Halogenation
Halogenation Halogenation is a basic and fundamental transformation in organic chemistry, and halogenated compounds are of extreme importance as building blocks in organic synthesis. The development of modern coupling reactions, such as the Suzuki-Miyaura and Mizoroki-Heck reactions, have greatly increased the demand for halogenated compounds as starting materials. In response to this situation, many novel halogenating reagents have been developed. The page below shows some examples of brominating and iodinating reagents, which have been released recently in our lineup of products. Example of brominating products: Dibromoisocyanuric acid (DBI) (1), which was first reported by Gottardi, is a mild and highly effective brominating reagent,1,2) and has superior brominating ability when compared with -bromosuccinimide (NBS), which is frequently used in organic synthesis. For instance, nitrobenzene was converted to the 3-bromonitrobenzene in 88% yield with 1 in conc. sulfuric acid in 5 min at 20ºC, 1a) but in only 70% yield with NBS in 50% sulfuric acid in 3 h at 85ºC. Thus 1 has been widely used as an effective brominating reagent.3) NO2 O
NO2 R O
1a)
Br
HN
Y. 88%
NH2
O
3a)
N
R
NHBr Y. 90-99%
Br N OH
N
O
Br
Br
NO2
Br
N N
O
DBI (1)
1b)
3b)
Y. 68%
Y. 69%
Example of iodinating products: 1,3-Diiodo-5,5’ -dimethylhydantoin (DIH) (2), which was first reported by Ozazi, is an useful iodinating reagent.4) 2 has higher reactivity and selectivity than molecular iodine or -iodosuccinimide (NIS), which are frequently used for iodination reaction. 2 is a pale yellow solid that does not sublime like molecular iodine, and has low toxicity, which makes it easier to handle. In addition, dimethylhydantoin, which is formed after the reaction, can easily be removed by aqueous extraction. 2 reacts smoothly at room temperature with aromatic compounds in the presence of sulfuric acid to give the corresponding iodinated aromatic compounds in a high regioselectivity and a high yield. Moreover, even low-activated substances such as nitrobenzene can easily be iodinated by using sulfuric acid.5) I
O
N
CH3 CH3 OMe
N
O
I
EtOH-conc.H2SO4, 20 °C, 10 min
NO2
OMe
2 (0.5 eq.)
Y. 97%
I
NO2
2 (1 eq.) 90% H2SO4, 0 °C, 60 min
Y. 75%
I COOH F
COOH
2 (1 eq.) 90% H2SO4, 0 °C, 90 min
Y. 75%
F I
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
85
Halogenation
F0342
D1868
D3812
F
Et Cl
Fluorination
F0335
Et
N
F
F F
F0334
F0344
F0225
N
F 2BF4
N
Cl
CH2Cl
F0343
N
Cl
BF4
N
F
F0327
B2F7
N
F0346
F
M1573 Et
F
CH3
CF3SO3 CH3
N
P1888
P1758 P1779
CH3
F
F
N
P0999
. (HF)x
KHF2
KF
CF3 F
N
O
T1909
T1592
Bu N Bu
N
SF3
F
T1295
Bu
CH3 BF4
CH3
F
SO3
F0328
CF3SO3
N
F
H0598
Et
BF4
N
F
CH3
CH3
N
F 2BF4
F0358
O O S N S O F O
CH3
N
N
F
F
CH3
CH3
N
Cl
N S
F
D2831 N
N
CF3SO3
T1635
F
F Ph HF2
Bu4N
Ph
Si
Bu4N
F Ph
Bu
Ph
F
Bu
Ph Bu
Sn
T1339 T1338 T1037 T1125
Ph
N Bu
Bu
H2F3 Bu
Bu
N Bu
F
Bu
T2026
T2027
(CH3CH2)4NF
. 4HF
(CH3CH2)4NF
T2023
. 3HF
(CH3CH2)3N
T2022
. 5HF
(CH3CH2)3N
. 3HF
Product No. Product Name F0342 D1868 D3812 D2831 F0335 F0358 F0344 F0225 F0334 F0343 F0327 F0346 F0328 H0598
86
2,6-Dichloro-1-fluoropyridinium Trifluoromethanesulfonate (Diethylamino)sulfur Trifluoride 1,1'-Difluoro-2,2'-bipyridinium Bis(tetrafluoroborate) 2,2-Difluoro-1,3-dimethylimidazolidine N-Fluorobenzenesulfonimide N-Fluoro-N '-(chloromethyl)triethylenediamine Bis(tetrafluoroborate) 1-Fluoro-2,6-dichloropyridinium Tetrafluoroborate 2-Fluoro-1-methylpyridinium p-Toluenesulfonate 1-Fluoropyridinium Pyridine Heptafluorodiborate 1-Fluoropyridinium Tetrafluoroborate 1-Fluoropyridinium Trifluoromethanesulfonate 1-Fluoro-2,4,6-trimethylpyridinium Tetrafluoroborate 1-Fluoro-2,4,6-trimethylpyridinium Trifluoromethanesulfonate Ishikawa's Reagent
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 5g
5g 25g
5g 5g 5g 5g 5g 5g 5g 25g
25g 100g 1g 10g 25g 25g 25g 25g 5g 25g 25g 5g 25g 500g
Halogenation
Product No. Product Name M1573 P1758 P1779 P1888 P0999 T1295 T1909 T1592 T1635 T1339 T1338 T1125 T1037 T2027 T2026 T2023 T2022
Unit Size
Morpholinosulfur Trifluoride Potassium Fluoride Potassium Fluoride Anhydrous (Spray-dried) Potassium Hydrogenfluoride Pyridinium Poly(hydrogenfluoride) Tetrabutylammonium Bifluoride Tetrabutylammonium Difluorotriphenylsilicate Tetrabutylammonium Difluorotriphenylstannate Tetrabutylammonium Dihydrogen Trifluoride Tetrabutylammonium Fluoride (70-75% in Water) Tetrabutylammonium Fluoride (1mol/L in Tetrahydrofuran) Tetrabutylammonium Fluoride (1mol/L in Tetrahydrofuran) Tetrabutylammonium Fluoride Hydrate Tetraethylammonium Fluoride Tetrahydrofluoride Tetraethylammonium Fluoride Trihydrofluoride Triethylamine Pentahydrofluoride Triethylamine Trihydrofluoride
1g
H0362
C0075
CH3 CH2
C0076
CH3
C1374
C0202
SO2NCl
H3C O
N CH3
Chlorination
25g 5g 5g 1g 5g 25g 100ml 25ml 25g
25ml
B1543
5g 300g 25g 500g 100g 25g 25g 5g 25g 500g 500ml 100ml 250g 10g 10g 10g 10g
H3C C C Cl
Na
H3C
ICl4
. xH2O
C0802
C0291
Cl Cl
SO2NNa
O
O
SO2NNa
. 2H2O
. 3H2O
N Cl
N Cl
ClCH2OCH3
CH3
O
O
CH3
C0460
D0318
D1645
M0094
M0970
Cl SO2NCl
Cl
O
Cl N
N
CH3 Cl
Cl
N
OCH3
S Cl O
Cl
O CH3OCH2
C Cl
CH3
O0082
D1003
T0620
T2040 T2048
T0611
O O
Cl Cl
Cl O
O
N
O
N
O
Cl
Cl
Product No. Product Name B1543 H0362 C0075 C0076 C1374 C0202
Cl
O
NNa
Benzyltrimethylammonium Tetrachloroiodate tert-Butyl Hypochlorite Chloramine B Chloramine T Trihydrate o-Chloramine T Chloromethyl Methyl Ether
S
Cl
O
N
N N
O
Cl CCl3 O
S Cl O
Cl
Unit Size 25g 25g 25g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 500g 500g 500g 25g 500g
87
Halogenation
Product No. Product Name
Unit Size
N-Chlorophthalimide N-Chlorosuccinimide Cyanuric Chloride Dichloramine T Dichloromethyl Methyl Ether Methanesulfonyl Chloride Methoxyacetyl Chloride Oxalyl Chloride Sodium Dichloroisocyanurate Thionyl Chloride Thionyl Chloride (ca. 1mol/L in Dichloromethane) Trichloroisocyanuric Acid Trichloromethanesulfonyl Chloride
C0802 C0291 C0460 D0318 D1645 M0094 M0970 O0082 D1003 T2040 T2048 T0620 T0611
25g 25g 25g 25g 25g 25g 25g 25g 25g
25g 5g
T1382
B2414
B0530
CH3 CH2
Bromination
B1016
O
N CH3 CH3
B3311
Br2
CH3
B2152
CH3 N CH3
Br
S
CH3
CH3
N Br
Br
S
D3976
O
D1265
Cl Cl
Br Cl
N
CH3
. HBr3
N
CH3
N
Br O
O
Br Br
O
P0928
CH3 CH3
O O
P0825
NaN
Br3 N H
T1284
O
O N
T1235 O
O
N(CH3)2
Cl Cl
O
Br
B2148
C C Cl
O
O HN
O
N
Br Br Cl
N Br Br
D1710
Br
Br
D1787
N
D3753 O
N
D1987
O
O
Br
O
B0662
Br
B0656
O NC
N H
Br3
B1697
O
500g 500g 500g 500g 250g 500g 500g 500g 500g 500ml 500ml 500g 25g
N N H
Br
Br
. xH2O O
Br
Br3 N H Br
Br
T2725 CH3
Bu Bu
Br
CH3 N CH3 Br3
N Bu Br3 Bu
P Br
Product No. Product Name T1382 B2414 B0530 B1016 B3311 B1697
88
Benzyltrimethylammonium Tribromide Bromine N-Bromoacetamide 2-Bromo-2-cyano-N,N-dimethylacetamide Bromodimethylsulfonium Bromide N-Bromophthalimide
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 5g 5g 5g 5g 5g
25g 500g 25g 25g 25g 25g
Halogenation
Product No. Product Name
Unit Size
N-Bromosaccharin N-Bromosuccinimide Bromotrichloromethane 1,8-Diazabicyclo[5.4.0]-7-undecene Hydrogen Tribromide 1,3-Dibromo-5,5-dimethylhydantoin Dibromoisocyanuric Acid 5,5-Dibromomeldrum's Acid (=5,5-Dibromo-2,2-dimethyl-4,6-dioxy-1,3-dioxane) 1,2-Dibromo-1,1,2,2-tetrachloroethane 4-Dimethylaminopyridinium Bromide Perbromide Monosodium Bromoisocyanurate Hydrate Pyridinium Bromide Perbromide 2,4,4,6-Tetrabromo-2,5-cyclohexadienone Tetrabutylammonium Tribromide Trimethylphenylammonium Tribromide Triphenylphosphine Dibromide
B2152 B0656 B0662 D3976 D1265 D3753 D1710 D1987 D1787 B2148 P0825 T1235 T1284 P0928 T2725
B1604
C1190
Iodination
H1221
N CH3 ICl2
5g 25g 5g 25g 25g 5g D3657 O
N
CH3
ICH2CH2Cl
CH3
CH3
I0604
25g 500g 500g 5g 500g 25g 25g 25g 25g 25g 500g 25g 500g 500g 25g
25g 5g 5g
CH3 CH2
5g 100g 25g
25g
N
I O
I
I0074 O
I2
HI
N
I
O
Product No. Product Name B1604 C1190 D3657 H1221 I0604 I0074
Benzyltrimethylammonium Dichloroiodate 1-Chloro-2-iodoethane (stabilized with Copper chip) 1,3-Diiodo-5,5-dimethylhydantoin Hydriodic Acid (57%) Iodine N-Iodosuccinimide
Unit Size 5g 1g 5g
5g
25g 25g
25g 5g 25g 300ml 500g 100g
References 2002, 83. 1) a) W. Gottardi, . 1968, , 815; b) W. D. Brown, A. H. Gouliaev, 2) S. C. Virgil, in , ed. by L. A. Paquette, John Wiley& Sons, Chichester, 2001, pp. 1560-1561. 3) a) Z. P. Demko, M. Bartsch, K. B. Sharpless, . 2000, , 2221; b) T. R. Walters, W. W. Zajac Jr., J. M. Woods, . 1991, , 316. 4) O. O. Orazi, R. A. Corral, H. E. Bertorello, . 1965, , 1101. 5) V. K. Chaikovskii, V. D. Filimonov, A. A. Funk, V. I. Skorokhodov, V. D. Ogorodnikov, . 2007, , 1291.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
89
New Oxidation of Primary & Secondary Alcohols
New Oxidation of Primary & Secondary Alcohols Oxidation reactions of primary alcohols and secondary alcohols to the corresponding aldehydes and ketones, respectively, are important reactions in organic synthesis. To date, many oxidizing agents utilizing chromium oxides such as Jones reagents, Sarett reagents, Collins reagents, and oxidizing methods using activated DMSO have been reported. Among them, the method to activate DMSO with oxalyl chloride is called Swern oxidation and is widely used as one of the most practical oxidation methods. However, the reaction temperature must be strictly controlled due to the thermal instability of the activated intermediates formed by the reaction of DMSO and oxalyl chloride in the Swern oxidation. Furthermore, because the byproduct, dimethyl sulfide, has a stench, it is considered to be unsuitable for mass production. Ph S Cl t
R
BuN
R1
1
HO R2
1
O
DBU (2.0 eq.), CH2Cl2
R2
Mukaiyama and co-workers have reported oxidation of alcohols using a sulfinimidoyl compound 1.1) According to their method, 1, nearly similar to activated DMSO in structure, oxidizes primary or secondary alcohols to the corresponding aldehydes or ketones in near quantitative yields under mild conditions. The Present Oxidation
Ph S Cl
R1 HO CH R2
tBuN
R1 S O CH tBuN R2
R1 S O CH N R2
Ph
Ph
tBu
R1 S + O C R2 NH
Ph tBu
1
Swern Oxidation
Cl
CH3 S Cl CH3
R1 HO CH R2
Cl
R1 CH3 S O CH R2 CH3
Et3N
R1 CH3 S O CH R2 H2C
R1 CH3 S + O C R2 CH3
+ HCl
1 reacts directly with alcohols without pre-activation to afford the corresponding carbonyl compounds. The oxidation method using 1 can be performed at room temperature without the strict control of reaction temperature required in the Swern oxidation. Moreover, the oxidation reaction is applicable to oxidation of acid-labile compounds since the reaction proceeds under basic conditions. Ph
R2 HO R1
S
t
N H
Bu (5 mol%)
2 NCS (1.1 eq.) K2CO3, MS4A CH2Cl2, 0 oC ~ rt
R2 O R1
Catalytic oxidation of alcohols to aldehydes or ketones has also been explored. To date, the oxidation methods using tetrapropylammonium perruthenate (TPAP) and 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO) as a catalyst have been reported and put into practical use. The oxidation method of alcohols reported by Mukaiyama and co-workers using sulfenamide 2 is one of such catalytic oxidation methods.2) In this method -chlorosuccinimide (NCS) can be used as a co-oxidant to yield the corresponding aldehydes and ketones from primary alcohols or secondary alcohols in near quantitative yields without requiring strict temperature control. The method using 2 is receiving much attention as a safe and simple catalytic oxidation method of alcohols. 90
Availability, price or specification of the listed products are subject to change without prior notice.
New Oxidation of Primary & Secondary Alcohols
R1 O R2 R 1 R2
Ph
O S
H
S
Ph
N H 2
t
N Bu
tBu
O
HCl
R1 R2
OH
Ph
Cl S
NtBu
O
N H
O
N Cl
O
Catalytic Cycle of 2
Matano and his group are developing an oxidation method of alcohols using hypervalent organobismuth compounds.3) This reaction progresses as shown below, and yields the desired carbonyl compounds in excellent yields. Cl Ar
Bi Cl
t
Ar
Ar2BiOBiAr2
Ar
H2 O
x2
BuOK H2O
R1 R2
[Ar3Bi=O]
H
O
Ar R1
Bi OH
[Ar2BiOH] Ar Ar
R1 O + ArH
OH R2
R2
R1 R2 Ar3BiCl2 DBU
H
O
Ar
Bi Cl
DBU
Ar Ar2BiCl
Ar
[DBUH] [Cl]
Cl Ar
Bi Cl
Ar [DBUH] [Ar2BiCl2]
Ar
This reaction has fairly high reactivity, and the reactions are completed at room temperature within a short period of time. Matano and co-workers are conducting comparative oxidation studies on the selectivity of the Dess-Martin periodinane and tris(2-methoxyphenyl)bismuth dichloride 3 upon conjugated alcohols and unconjugated alcohols. Ar3BiCl2/DBU
RR'CHOH + EtOH
or Dess-Martin Reagent CDCl3, rt,15 min
Ar=o-MeOC6H5 3
RR'C=O + MeCHO
RR'CHOH Ph Ph
OH OH
Ratio of RR'C=O to MeCHO Dess-Martin Reagent
Ar3BiCl2/DBU 98 : 2
91 : 9
96 : 4
90 : 10
95 : 5
75 : 25
Me Ph
OH
According to their studies, 3 has higher selectivity over Dess-Martin periodinane upon conjugated alcohols. 3 is becoming recognized as a non-explosive, non-toxic, highly reactive and selective oxidizing agent. Recently, Katsuki and co-workers reported that the oxidation method of alcohols using (nitrosyl)Ru-Salen complex as a catalyst. This catalyst is activated by photo-irradiation and can be used to oxidize primary alcohols to aldehydes selectively.4) This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
91
New Oxidation of Primary & Secondary Alcohols
CHO
OH catalyst, hν, air
+
OH
quant.
d6-benzene, rt, 12 h CH3 CH3 CH3 N
O
0%
CH3 NO N Ru
catalyst = (CH3)3C
O
Cl O
C(CH3)3
C(CH3)3 (CH3)3C
B2240
B2188
C1944
CH3 S
CH3
NH C CH3
Cl
H3C CH3 H3C CH3 N NO N Ru O C(CH3)3 (CH3)3C O Cl C(CH3)3 (CH3)3C
S N C CH3
CH3
CH3
T1956
T2038
Bi
Cl
OCH3
CF3
Bi
Bi
T1837 T2507 T1956 T2038 T1957
BF4
Bi
Cl CH3
CH3
Cl CF3
CH3
Product No. Product Name B2240 B2188 C1944
CH3
Cl
CH3 Cl Bi
Cl
Cl OCH3
T2507
T1957 CF3
CH3O Cl
T1837
N-tert-Butylbenzenesulfenamide N-tert-Butylbenzenesulfinimidoyl Chloride Chloronitrosyl[N,N '-bis(3,5-di-tert-butylsalicylidene)-1,1,2,2-tetramethylethylenediaminato]ruthenium(IV) Triphenylbismuth Dichloride Triphenyl-2,6-xylylbismuthonium Tetrafluoroborate Tris(2-methoxyphenyl)bismuth Dichloride Tris(4-trifluoromethylphenyl)bismuth Dichloride Tri-o-tolylbismuth Dichloride
Unit Size 1g
5g 1g
25g 5g
100mg 5g 100mg 1g 1g 5g 1g 1g 5g
References 1) T. Mukaiyama, J. Matsuo, M. Yanagisawa, . 2000, 1072; T. Mukaiyama, J. Matsuo, H. Kitagawa, . 2000, 1250; J. Matsuo, H. Kitagawa, D. Iida, T. Mukaiyama, . 2001, 150; J. Matsuo, D. Iida, K. Tatani, T. Mukaiyama, . 2002, , 223; K. Tahara, 2002, , 708; Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 2002 37753, 2002. 2) T. Mukaiyama, J. Matsuo, D. Iida, H. Kitagawa, . 2001, 846; J. Matsuo, D. Iida, H. Yamanaka, T. Mukaiyama, 2003, , 6739; Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 2002 026627, 2002. 3) Y. Matano, H. Nomura, . 2002, , 3028; Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 2003 113130, 2003; Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 2005 023052, 2005. 4) A. Miyata, M. Murakami, R. Irie, T. Katsuki, . 2001, , 7067.
92
Availability, price or specification of the listed products are subject to change without prior notice.
Oxidation
Oxidation Oxidation, making its target substance lose electrons, is one of the most basic reactions in organic chemistry and is exemplified by the combination with oxygen or a dehydrogenation reaction. In particular, it is often used for the transformation of alcohols to the corresponding aldehydes, ketones or carboxylic acids. Heavy metal compounds, such as chromium (VI) oxide and potassium permanganate, have been exploited for many years. Especially, chromium (VI) oxide has been utilized abundantly, based on the report of the control of oxidization powers by Jones or Sarett.1) Furthermore, chromium (VI) oxide have been improved as the Collins reagent2), PCC3) and PDC4) and are used in many fields. On the other hand, the Dess-Martin periodinane5), the Mukaiyama oxidizing agent6) and oxoammonium salts have been developed without containing harmful metals. Moreover, oxidation reactions employing inexpensive sodium hypochlorite or molecular oxygen have also been reported in the presence of oxidation catalysts such as tetrapropylammonium perruthenate (TPAP)7) and TEMPO8). This section shows the typical oxidizers and the catalysts used for oxidation reactions.
B2134
B1375
B1123
O Se
OH
Metal Oxidants
L0021 H3C CH3 H3C CH3 N NO N Ru O C(CH3)3 (CH3)3C O Cl C(CH3)3 (CH3)3C
N H
N
C O
2
L0021
12MoO3 . H3PO4
. xH2O
Q0058
N H
2
N Bu
FCrO3
N H
Cr2O722
Bu
Pr ReO4
Pr
N Pr
RuO4
Pr
Product No. Product Name B2134 B1375 B1123 C1944
2
T1559
Bu Bu
OsO4
Pb
P1088
N H
Cr2O7 2
N Bu
4
Cr2O72
ClCrO3
T1803
Ag2
Bu
P1910
O
P0931
KMnO4
O
OCH3
O0308
CH3 C O
P0930
S0815
Se
Bu
C1944
P1742
Bu
O CH3O
Benzeneseleninic Acid Bis(4-methoxyphenyl) Selenoxide Bis(tetrabutylammonium) Dichromate Chloronitrosyl[N,N '-bis(3,5-di-tert-butylsalicylidene)-1,1,2,2-tetramethylethylenediaminato]ruthenium(IV) Lead Tetraacetate (contains Acetic Acid)
Unit Size 5g 1g
25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 5g 10g 100mg 500g
93
Oxidation
Product No. Product Name O0308 P1910 P1742 P0930 P0931 P1088 Q0058 S0815 T1803 T1559
Unit Size
Osmium Tetroxide (4% in Water) Phosphomolybdic Acid Hydrate Potassium Permanganate Pyridinium Chlorochromate Pyridinium Dichromate Pyridinium Fluorochromate Quinolinium Dichromate Silver(II) Picolinate Tetrabutylammonium Perrhenate Tetrapropylammonium Perruthenate
25g
10ml 100g 300g 500g 500g 5g 10g 1g 5g 5g
100g 25g
1g 1g
B2897
D3428
D3429
CH3
CH3
CH3
CH3
Perchlorates N
N ClO4
CH3
M1774
M2072
M1775
N
ClO4
CH3
T0836
CH3
T0839
CH3
CH3
ClO4
CH2CH3
Bu CH3
ClO4
CH3
CH3
CH3
CH3
Bu
CH3
N Bu
CH3CH2 N CH2CH3 ClO4
ClO4
CH2CH3
Bu N CH3
N
N CH3
ClO4
ClO4
CH3
T0841
CH3 CH3 N CH3
ClO4
CH3
Product No. Product Name B2897 D3428 D3429 M1774 M2072 M1775 T0836 T0839 T0841
Unit Size
9-(2-Biphenylyl)-10-methylacridinium Perchlorate 9-(2,5-Dimethylphenyl)-10-methylacridinium Perchlorate 9-(2,6-Dimethylphenyl)-10-methylacridinium Perchlorate 9-Mesityl-10-methylacridinium Perchlorate 9-Mesityl-2,7,10-trimethylacridinium Perchlorate 10-Methyl-9-phenylacridinium Perchlorate Tetrabutylammonium Perchlorate Tetraethylammonium Perchlorate Tetramethylammonium Perchlorate
B3152
94
1g 25g
B3497
O
Organic Peroxides
1g 1g 1g 1g
B3153
CH3
O
C O O C
CH3
5g 5g 5g 5g 1g 5g 500g 25g 25g
Si CH3
CH3
CH3 O O Si
CH3
CH3
Availability, price or specification of the listed products are subject to change without prior notice.
CH3 C OOH CH3
Oxidation
C2223
C2392 C0357
D3411
M0927
O
O
CH3
CH3
C OOH
CH3
C O Mg2+
CH3 C O O C CH3
C OOH
CH3
CH3
CH3
. 6H2O
C OOH
Cl
2
O
Product No. Product Name B3152 B3497 B3153 C2392 C0357 C2223 D3411 M0927
Unit Size
Benzoyl Peroxide (wetted with ca. 25% Water) Bis(trimethylsilyl) Peroxide (contains Hexamethyldisiloxane) (ca. 30% in Hexane) tert-Butyl Hydroperoxide (70% in Water) 3-Chloroperoxybenzoic Acid (contains min. 17% Water and min. 6% 3-Chlorobenzoic Acid) 3-Chloroperoxybenzoic Acid (contains ca. 30% Water) Cumene Hydroperoxide (contains ca. 20% Aromatic Hydrocarbon) Di-tert-butyl Peroxide Monoperoxyphthalic Acid Magnesium Salt Hexahydrate
B1175
B1616 O
O CF3
C O
I
O C CF3
B2121
C O
Hypervalent Iodine Compounds
100g 25g
25g
O
O CF3
25g
25g 5g 100g 500g 250g 100g 100ml 500g
I
O C CF3
F
F
F
F
CH3 CH3 C OO
I
O
CH3
O
F
D2045
P1015
I0330
I0479
I0072 O
AcO OAc O AcO I
O
O HO
I
CH3
O S
CH3 C O
O
O
O I
O C CH3
CH3 C O
O I
O C CH3
I
O
CH3
CH3
n
CH3
I0073
P1415 HO
I
O
O
O C CH3
O
P
I O C CH3 O
Product No. Product Name B1175 B1616 B2121 D2045 P1015 I0330 I0479 I0072 I0073 P1415
[Bis(trifluoroacetoxy)iodo]benzene [Bis(trifluoroacetoxy)iodo]pentafluorobenzene 1-(tert-Butylperoxy)-1,2-benziodoxol-3(1H)-one Dess-Martin Periodinane [Hydroxy(tosyloxy)iodo]benzene Iodobenzene Diacetate Iodomesitylene Diacetate Iodosobenzene 2-Iodosobenzoic Acid Poly[4-(diacetoxyiodo)styrene]
Unit Size 5g
1g 10g
5g 5g 25g 5g
1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 1g 1g 25g 25g 250g 25g 5g 10g 5g
95
Oxidation
D3219
D3220
L0069 N(CH3)2
Cl
-Oxides
N
Cl
CH3
. xH2O
N O
P0557
T0466
CH3 O
T1362 CH3
N N O
CH3 N CH3
CH3
. 2H2O
CH3
N CH3 O
O
O
Product No. Product Name D3219 D3220 L0069 M0981 P0557 T0466 T1362
Unit Size
2,6-Dichloropyridine N-Oxide 4-(Dimethylamino)pyridine N-Oxide Hydrate 2,6-Lutidine N-Oxide 4-Methylmorpholine N-Oxide (50% in Water, ca. 4.8mol/L) Pyridine N-Oxide Trimethylamine N-Oxide Dihydrate Trimethylamine N-Oxide Anhydrous
A1348
1g 25ml 25g 25g 1g
H0878 O
HN C CH3 CH3 CH3
N
OCH3
O C
CH3
CH3
CH3
CH3
O
5g 5g 25g 500ml 500g 500g 5g
M1197
O
TEMPOs
CH3
O
O
M0981
N
CH3
CH3 N
CH3
CH3
CH3
N
CH3
O
O
T1560
CH3 CH3
CH3 N
CH3
O
Product No. Product Name A1348 H0878 M1197 T1560
Unit Size
4-Acetamido-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Benzoate Free Radical 4-Methoxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical 2,2,6,6-Tetramethylpiperidine 1-Oxyl Free Radical
T1837
5g 1g 1g 5g
T2507
T1956 CH3
Cl
Organic Bismuth Compounds
Bi
CH3O Cl BF4
Bi
Cl CH3
96
25g 5g 5g 25g
Availability, price or specification of the listed products are subject to change without prior notice.
Bi Cl OCH3
OCH3
Oxidation
T2038
T1957 CF3
CH3 Cl
Cl CF3
Bi
CH3
Bi
Cl
Cl CF3
CH3
Product No. Product Name T1837 T2507 T1956 T2038 T1957
Unit Size
Triphenylbismuth Dichloride Triphenyl-2,6-xylylbismuthonium Tetrafluoroborate Tris(2-methoxyphenyl)bismuth Dichloride Tris(4-trifluoromethylphenyl)bismuth Dichloride Tri-o-tolylbismuth Dichloride
5g 1g 5g 1g 5g
100mg 1g 1g
A2065
B2151
T0617
O
O
NH C CH3 CH3
CH3
Others
CH3
N O
B0656
B2240
O
N
Bu
Br
2
Br O
BF4
C1326 CH3
CH3
CH3
H3C O
S N C CH3
H3C C C Cl
N
H3C
Br
C1327
C1806 CH3
Br
S2O8 2
N Bu
CH3 Cl
CH3
O
Br
H0362
CH3 NH C CH3
Bu
CH3
B2188
S
Bu
C0076
T0061
T0970
Cl
CH3
S O O O
SO2NNa
O Cl
O Cl
Cl
Cl
Cl
O
(NH4)2Ce(NO3)6
N O S O O
D0318
. 3H2O
Cl
I0074
O0310
Cl
O
CH3
Cl
P0998
T1559
SO2NCl2
O
N I
O
. SO3
2KHSO5 . KHSO4. K2SO4
Pr Pr
N
N Pr
RuO4
Pr
CH3
Product No. Product Name A2065 B2151 T0617 B0656 B2240 B2188 H0362 C1326 C1327 C1806 C0076 T0061 T0970 D0318
4-Acetamido-2,2,6,6-tetramethyl-1-oxopiperidinium Tetrafluoroborate Bis(tetrabutylammonium) Peroxydisulfate Bromanil N-Bromosuccinimide N-tert-Butylbenzenesulfenamide N-tert-Butylbenzenesulfinimidoyl Chloride tert-Butyl Hypochlorite (2R,8aS)-(+)-(Camphorylsulfonyl)oxaziridine [Asymmetric Oxidizing Reagent] (2S,8aR)-(-)-(Camphorylsulfonyl)oxaziridine [Asymmetric Oxidizing Reagent] Ceric Ammonium Nitrate Chloramine T Trihydrate Chloranil o-Chloranil Dichloramine T
Unit Size
25g 1g
5g 5g 100g 5g 1g 25g 1g 1g 50g 25g 25g 5g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 25g 25g 500g 25g 5g 500g 5g 5g 500g 500g 500g 25g 500g
97
Oxidation
Product No. Product Name N-Iodosuccinimide Potassium Peroxymonosulfate [>45%(T) as KHSO5] Pyridine - Sulfur Trioxide Complex Tetrapropylammonium Perruthenate
I0074 O0310 P0998 T1559
Unit Size 5g
25g 25g 25g 1g
100g 500g 500g 5g
Many oxidizing agents may cause combustion or explosion upon mixture with flammable materials or upon exposure to heat, shock, and friction etc. Sufficient safety measures, such as using safety shields, wearing protective equipment, and using extreme caution should be taken when working with these reagents as well as disposing of the reagents.
References 1) K. Bowden, I. M. Heilbron, E. R. H. Jones, . 1946, 39; Review: S. V. Ley, A. Madin, 1991, , 253. 2) J. C. Collins, W. W. Hess, F. J. Frank, . 1968, , 3363. 3) E. J. Corey, J. W. Suggs, . 1975, , 2647. 4) E. J. Corey, G. Schmidt, . 1979, , 399. 5) D. B. Dess, J. C. Martin, . 1983, , 4155; R. E. Irekand, L. Liu, . 1993, , 2899. 6) J. Matsuo, D. Iida, K. Tatani, T. Mukaiyama, . 2002, , 223. 7) W. P. Griffith, S. V. Ley, G. P. Whitcombe, A. D. White, . 1987, 1625; Review: S. V. Ley, J. 1994, 639. Norman, W. P. Griffith, S. P. Marsden, 8) O. L. Lebelev, S. N. Kazarnovskii, . 1960, , 1631; Review: A. E. J. de Nooy, A. C. Besemer, H. van 1996, 1153. Bekkum,
98
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Reduction
Reduction Reduction is a chemical reaction in which the target substances receive electrons, and is one of the most fundamental reactions in organic chemistry including the deoxygenation reaction and the hydrogenation reaction. The well-known reducing agents include metal hydrides such as LiAlH41) , boranes used in the hydride reduction, and hydrazine used in the Wolff-Kishner reduction.2) Sodium tris(1,1,1,3,3,3-hexafluoroisopropoxy)borohydride (1) is a selective reducing agent developed by Toshima . Aldehydes are selectively reduced in the presence of ketones and other reducible functions using 1 to afford the corresponding primary alcohols in high yields.3) OCH(CF3)2 1:
H B OCH(CF3)2
Na
OCH(CF3)2 O
OTBS
CH3
O
1 / THF (3 eq.) CHO
Hexafluoroisopropanol, 25 °C, 1.5 h
OTBS OH
CH3 Y. 94%
In addition, the radical reductive reaction using silane compounds tris(trimethylsilyl)silane4) and tetraphenyldisilane (TPDS)5) as radical reducing agents has been developed avoiding the use of highly toxic tin compounds. This section shows the typical reducing agents. Table. Comparison of reactivities of hydride reducing agents for carbonyl compounds and imines Reagents
NaBH(OCOCH3)3 S0394
Reactions
Reactivity :
High
THF・BH3 T2346
NaBH3CN S0396
Middle
NaBH4 S0480
LiBH4 L0186
LiAlH4 L0170, L0203
Me2S・BH3 D1843 PhNEt2・BH3 D2581
Low
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
99
Reduction
D2971 D2972
L0159
LiAlH4
[(CH3)2CHCH2]2AlH
Aluminum Hydrides
Metal Hydrides
L0170 L0203
S0467
OC(CH3)3 Li
H Al
OC(CH3)3
NaAl(OCH2CH2OCH3)2H2
OC(CH3)3
Product No. Product Name D2971 D2972 L0170 L0203 L0159 S0467
Unit Size
Diisobutylaluminum Hydride (19% in Hexane, ca. 1.0mol/L) Diisobutylaluminum Hydride (17% in Toluene, ca. 1.0mol/L) Lithium Aluminum Hydride (10% in Tetrahydrofuran, ca. 2.5mol/L) Lithium Aluminum Hydride (Powder) Lithium Tri-tert-butoxyaluminum Hydride (20% in Tetrahydrofuran, ca. 0.7mol/L) Sodium Bis(2-methoxyethoxy)aluminum Dihydride (70% in Toluene, ca. 3.6mol/L)
T1473
25g 25g
(CH2)7CH3 CH3(CH2)7 Sn
CH3(CH2)3 Sn H
H
(CH2)7CH3
(CH2)3CH3
Product No. Product Name T1473 T1572
Unit Size
Tributyltin Hydride (stabilized with BHT) Tri-n-octyltin Hydride
S0481
25g
H
Zr
Product No. Product Name S0481 Z0010
100
250g 10g
Z0010
NaH
Other Metal Hydrides
500ml 500ml 100ml 100g 100ml 500g
T1572
(CH2)3CH3
Tin Hydrides
100ml 100ml
Sodium Hydride (60%, dispersion in Paraffin Liquid) Zirconocene Chloride Hydride
Cl
Unit Size 1g
5g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
100g 25g
Reduction
B1139
L0186
L0164
P 3
Borohydrides
Cu
CH(CH3)CH2CH3
. BH4
LiBH4
Li
H B CH(CH3)CH2CH3 CH(CH3)CH2CH3
P 3
P1681
P1380
S0480
CH3
KBH4
CH3CH2CH
S0810
3
BH
OCH(CF3)2 Bu
OCH(CF3)2
N Bu
CH3 N CH3
CH3 BH4
OAc
CH3 N CH3 AcO B H CH3
CH3
Bu
NaBH(OCOCH3)3
T1553
CH3 BH4
S0394
NaBH3CN
T0852
Bu Na
H B OCH(CF3)2
NaBH4
K
T0917
S0396
OAc
Product No. Product Name B1139 L0186 L0164 P1681 P1380 S0480 S0396 S0394 S0810 T0917 T0852 T1553
Unit Size
Bis(triphenylphosphine)copper Tetrahydroborate Lithium Borohydride (ca. 3mol/L in Tetrahydrofuran) Lithium Tri-sec-butylborohydride (21% in Tetrahydrofuran, ca. 1.0mol/L) Potassium Borohydride Potassium Tri-sec-butylborohydride (ca. 1.0mol/L in Tetrahydrofuran) Sodium Borohydride Sodium Cyanoborohydride Sodium Triacetoxyborohydride Sodium Tris(1,1,1,3,3,3-hexafluoroisopropoxy)borohydride Tetrabutylammonium Borohydride Tetramethylammonium Borohydride Tetramethylammonium Triacetoxyborohydride
100g 25g 25g 5g 5g 5g
B1827
T2346
CH3
CH3
CH3 C S(CH2)2S
Borane Complexes
Boranes
D2581
5g 100ml 100ml 100g 100ml 500g 250g 100g 5g 25g 25g 25g
CH3
. 2BH3
.
C CH3 CH3
BH3
O
D1843
CH2CH3 N
.
BH3
CH3SCH3
. BH3
CH2CH3
Product No. Product Name B1827 T2346
1,2-Bis(tert-butylthio)ethane Borane Borane - Tetrahydrofuran Complex (8.5% in Tetrahydrofuran, ca. 0.9mol/L)
D2581 D1843
N,N-Diethylaniline Borane Dimethyl Sulfide Borane
(stabilized with Sodium Borohydride)
Unit Size 1g 100ml 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500ml 100g 25ml
101
Reduction
B1264
B3018
CH3
Borane-Amine Complexes D1842
CH3 C NH2
N
CH3
T1180
. BH3
B1569 H N
. BH3
. BH3 CH3
. BH3
. BH3 N
O
T1181
CH2CH3 CH3NHCH3
M0898
CH3
. BH3
CH3CH2 N
CH3 N
. BH3
CH3
CH2CH3
Product No. Product Name B1264 B3018 M0898 B1569 D1842 T1180 T1181
Unit Size
Borane - tert-Butylamine Complex Borane - 2-Methylpyridine Complex Borane - Morpholine Complex Borane - Pyridine Complex Dimethylamine Borane Triethylamine Borane Trimethylamine Borane
C1614
5g 5g 25ml 25g
C2023 C1615 CH3
CH3 B Cl
Other Boranes
CH3
B Cl CH3
CH3
CH3
2
2
Product No. Product Name C1614 C2023 C1615
Unit Size
(+)-B-Chlorodiisopinocampheylborane (58% in Hexane, ca. 1.6mol/L) (-)-B-Chlorodiisopinocampheylborane (60% in Heptane, ca. 1.7mol/L) (-)-B-Chlorodiisopinocampheylborane (60% in Hexane, ca. 1.7mol/L)
C1492
100ml 100ml 100ml
C0778
D2403
CH(CH3)2
Silanes
CH3CH2SiH2CH2CH3
Si H
Si H OCH2CH3
P1291
CH3
H
Si H
Si
SiH2
CH3
CH3
D1825
D2406 D2820
CH3
102
Cl
CH(CH3)2
D2196
OCH2CH3
CH3
H Si Cl
D3761
25g 25g 25g 250ml 500g 25g 25g
SiH3
CH3
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Reduction
T1437
T1896
CH3 CH3
T0398
O Si
H
H
CH3
T1533
H Si Si
Si
H
H
i
(CH2)5CH3 CH3(CH2)5 Si H
CH2CH3
(CH2)5CH3
T1463
Si(CH3)3
Pr
Si
CH3CH2 Si H
Cl
Cl
T0661
T1334
CH2CH3
Cl
CH3
Si
i Pr
T0662
H
Si
H
(CH3)3Si
Si H Si(CH3)3
i Pr
Product No. Product Name C1492 C0778 D2403 D3761 D2196 D2406 D2820 D1825 P1291 T1437 T1896 T0398 T0662 T1334 T1533 T0661 T1463
Unit Size
Chlorodiisopropylsilane Chlorodimethylsilane Diethoxymethylsilane [Hydrosilylating Reagent] Diethylsilane Dimethylphenylsilane Diphenylsilane Diphenylsilane Methyldiphenylsilane Phenylsilane 1,1,3,3-Tetramethyldisiloxane 1,1,2,2-Tetraphenyldisilane Trichlorosilane Triethylsilane Trihexylsilane Triisopropylsilane Triphenylsilane Tris(trimethylsilyl)silane (stabilized with TBBP)
5ml 25ml 5ml 5g 5g
5g
5ml
H0174
H2NNH2 .2HBr
. xH2O
H2NNH2 .2HCl
I0777 SO2NH N C
H2NNH2 . HBr
H0170
H0169
H2NNH2 . H2O
H0173
25ml 5ml
H0172 H0204 H0697
Hydrazines
5ml 25ml 1g 25g 25ml
25ml 250ml 25ml 25ml 25ml 25g 25g 25ml 25ml 250ml 5g 500g 250ml 10g 100ml 25g 25ml
H2NNH2
. HCl
NO2
CH3 CH3
Product No. Product Name
Unit Size
H0172 H0204 H0697 H0169 H0170 H0173
25ml 25g 10g 25g 25g 25g
Hydrazine Monohydrate Hydrazine Monohydrate (79%) Hydrazine Anhydrous Hydrazine Dihydrobromide Hydrazine Dihydrochloride Hydrazine Monohydrobromide
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500ml 500g 100g 500g 500g 500g
103
Reduction
Product No. Product Name H0174 I0777
Unit Size
Hydrazine Monohydrochloride N '-Isopropylidene-2-nitrobenzenesulfonohydrazide
25g
D3775
H1221
S0494
O
O CH3CH2O C
C OCH2CH3
SmI2
HI
Others
CH3
T0430
T0488
500g 5g
N H
CH3
T0519
T1819
CH3 OCH3 O CH3
O
P
CH3O O
P
P
Se
CH3
Product No. Product Name D3775 H1221 S0494 T0430 T0488 T0519 T1819
P
OCH3
Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Hydriodic Acid (57%) Samarium(II) Iodide (ca. 0.1mol/L in Tetrahydrofuran) Triethyl Phosphite Trimethyl Phosphite Triphenylphosphine Triphenylphosphine Selenide
Unit Size 1g
5g
25ml 25ml 25g
25g 300ml 25ml 500ml 500ml 500g 5g
Many reducing agents may spontaneously ignite on contact with air, or may react violently with water to produce flammable gases. Sufficient safety measures, such as using safety shields, wearing protective equipment, and using extreme caution should be taken when working with these reagents as well as disposing of the reagents.
References 1972, 217. 1) Review: J. Malek, M. Cerny, 2) Review: N. Kishner, . 1911, , 582; L. Wolff, . 1912, , 86; R. O. Hutchins, M. K. 1991, , 327. Hutchins, 2008, 3) Y. Kuroiwa, S. Matsumura, K. Toshima, , 2523. 4) C. Chatgilialoglu, D. Griller, M. Lesage, . 1988, , 3641. 5) O. Yamazaki, H. Togo, S. Matsubayashi. M. Yokoyama, . 1998, , 1921.
104
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Mitsunobu Reaction
Mitsunobu Reaction O O O O H H EtO C N N C OEt EtO C N N C OEt O
R1 OH R2
+
O
R1
R3 C OH
O C R3 R2 O PPh3
PPh3
The Mitsunobu reaction is a unique dehydration-condensation reaction between alcohols and various nucleophiles using the redox system comprised of diethyl azodicarboxylate (DEAD) and triphenylphosphine (TPP).1) The reactions proceed under mild conditions, and a wide variety of compounds can be used as nucleophiles, for example, carboxylic acids, active methylenes, imides, thiols, etc. The reaction between secondary alcohols and nucleophiles yields products with Walden inversion. The Mitsunobu reaction has been used widely in organic synthesis. Due to its utility, efforts have been made to expand application of the Mitsunobu reaction, and modified reactions have been reported.2) For example, by using azodicarboxamides instead of azodicarboxylates the Mitsunobu reaction is being applied to weak-acidity nucleophiles with a higher p a value.3) Methods have been reported for the easy removal of phosphine oxide, a reaction by-product, by utilizing phosphines which have an intramolecular basic component4) and diphenylphosphino polystyrene resin.5) The modified method using a catalytic amount of DEAD and a stoichiometric amount of PhI(OAc)2 as a reoxidizing reagent has also been reported, which makes it possible to dramatically reduce the hydrazine byproduct.6) Moreover, the DEAD-TPP reaction system is generally not applicable to sterically-hindered tertiary alcohols. Mukaiyama and Kuroda . have reported the modified method using phenoxydiphenylphosphine (1), instead of TPP. In this system, condensation of tertiary alcohols and 2-nitrobenzoic acid affords the corresponding ester with inversion of the configuration as shown below.7) O2N NO2 Me Et
PhOPPh2 1
OH
O
DEAD
+
CO2Bn
COOH Toluene, rt
Me
O
Et
CO2Bn Y. 52%, 96% e.e.
In 1994, Tsunoda and co-workers reported a new Mitsunobu reagent, cyanomethylenetributylphosphora ne (2).8) This reagent alone can achieve the functions of DEAD and TPP. It is shown to be very effective in the reaction of secondary alcohols and active methylene of p a value above 23.4. Accordingly, 2 is a reagent which increases the usefulness of the Mitsunobu reaction. Bu
MeS
SO2Tol
+ OH
Bu P Bu
CH
CN 2
Benzene, 150 °C
pKa 23.4 Tol = Tolyl
MeS
SO2Tol
Y. 88 %
A1458
A1051
O
Azodicarboxylates & Amides
Me2N
O
O
C N N C
A1332
NMe2
O
N C N N C N
O
O
Cl3CH2CO C N N C OCH2CCl3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
105
Mitsunobu Reaction
A0776
D3544
O
A0705
O
O
BnO C N N C OBn
t
O
O
BuO C N N C Ot Bu
A1246
O
A0882
O iPrO
EtO C N N C OEt
O
O
C N N C OiPr
Product No. Product Name A1458 A1051 A1332 A0776 D3544 A0705 A1246 A0882
O
MeO C N N C OMe
Unit Size
1,1'-Azobis(N,N-dimethylformamide) 1,1'-(Azodicarbonyl)dipiperidine Bis(2,2,2-trichloroethyl) Azodicarboxylate Dibenzyl Azodicarboxylate (40% in Dichloromethane, ca. 1.7mol/L) Di-tert-butyl Azodicarboxylate (20% in Toluene) Diethyl Azodicarboxylate (40% in Toluene, ca. 2.2mol/L) Diisopropyl Azodicarboxylate (40% in Toluene, ca. 1.9mol/L) Dimethyl Azodicarboxylate (40% in Toluene, ca. 2.7mol/L)
D2411
1g
5g 5g
25g 25g 5g 25g 25g 250g 250g 25g
25g 25g
D1019
D2478
Et
Phosphines (Mitsunobu Reaction)
D2766
D2471
(CH3)2N
P
P
P
Et
I0583
P1843
T0361
Bu
CH3 CH2
P
P
P
T1165
t t
Bu
P
T0503 (CH2)5CH3
P t Bu
CH3(CH2)5 P (CH2)5CH3
T0519 (CH2)7CH3
CH3(CH2)7 P
P
(CH2)7CH3
Product No. Product Name D2411 D1019 D2478 D2766
P Bu
T1005
Bu
P
Bu
O P
CH3
N
T1912
CH
Dicyclohexylphenylphosphine Diethylphenylphosphine 4-(Dimethylamino)phenyldiphenylphosphine 4-Diphenylphosphinomethyl Polystyrene Resin cross-linked with 2% DVB (200-400mesh)
Unit Size 1g 1ml 1g
(0.5-1.0mmol/g)
D2471 I0583 P1843 T0361 T1912 T1165 T1005 T0503 T0519
106
Diphenyl-2-pyridylphosphine Isopropyldiphenylphosphine Phenoxydiphenylphosphine Tributylphosphine Tri-tert-butylphosphine Tricyclohexylphosphine (contains Tricyclohexylphosphine Oxide) (ca. 18% in Toluene, ca. 0.60mol/L) Trihexylphosphine Tri-n-octylphosphine Triphenylphosphine
1g 5g 25ml 25ml 25ml 25g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
5g 5ml 5g 5g 1g 5g 25g 500ml 5g 500ml 25ml 500ml 500g
Mitsunobu Reaction
C1500
Bu
Modified Mitsunobu Reaction (Tsunoda Reagent) Product No. Product Name C1500
Cyanomethylenetributylphosphorane
Bu
P CH CN Bu
Unit Size 1g
5g
25g
On exposure to heat, impact, friction, etc., azodicarboxylic acid derivatives are prone to highly exothermic reaction or explosive decomposition. Sufficient safety measures, such as usage of safety shield, wearing of protective equipment, and extreme caution should be taken, when using these compounds, from the opening up to the disposal of the reagents.
References 1981, 1. 1) O. Mitsunobu, 2001, 1999, number 2) S. Ito, , 567; T. Onozawa, , 10. 3) T. Tsunoda, Y. Yamamiya, S. Ito, . 1993, , 1639; T. Tsunoda, J. Otsuka, Y. Yamamiya, S. Ito, . 1994, 539; S. Ito, T. Tsunoda, . 1994, , 2071; T. Tsunoda, Y. Yamamiya, Y. Kawamura, S. Ito, 1999, . 1995, , 2529; K. Tahara, T. Onozawa, , 633. 4) L. D. Arnold, H. I. Assil, J. C. Vederas, . 1989, , 3973; A. R. Tunoori, D. Dutta, G. I. Georg, . 1998, , 8751. 5) R. A. Amos, R. W. Emblidge, N. Havens, . 1983, , 3598. 6) T. Y. S. But, P. H. Toy, . 2006, , 9636. 7) K. Kuroda, Y. Maruyama, Y. Hayashi, T. Mukaiyama, . 2008, , 836; K. Kuroda, Y. Maruyama, Y. Hayashi, T. Mukaiyama, . 2009, , 381; T. Mukaiyama, K. Kuroda, Y. Mukaiyama, Y. Hayashi, . 2008, 2010, , 1072; Review: T. Mukaiyama, K. Kuroda, Y. Maruyama, , 63. 8) T. Tsunoda, M. Nagaku, C. Nagino, Y. Kawamura, F. Ozaki, H. Hiroki, S. Ito, . 1995, , 2531; T. Tsunoda, F. Ozaki, N. Shirakata, Y. Tamaoka, H. Yamamoto, S. Ito, . 1996, , 2463.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
107
Condensation & Active Esterification
Condensation & Active Esterification The synthesis of carboxylic esters is one of the most fundamental and important processes for producing useful compounds in organic chemistry. The classical esterification reaction is condensation of a carboxylic acid and an alcohol under acidic conditions. This is an equilibrium reaction, and in order to effectively generate the ester, the equilibrium need to be shift toward the ester. To achieve this equilibrium shift requires adding one of the substrates in large excess and the removal of the generated water by distillation. However, when both carboxylic acid and alcohol are expensive and not easily available, it is not economical to use one of the substrates in large excess. Thus the classical esterification method is not the best method to use in such a case. Furthermore, when the substrate is unstable to heat, the classical method does not always yield the desired results. Since esterification is a basic reaction that is applied to many different types of substrates, there is a need for alternative methods which proceed under mild conditions without the need for using large excess of one of the substrates. Over the years, there has been much research done by many chemists, and many useful methods have been reported. NO2 O
O
NO2
O Me Me 1 (1.1 eq.)
O R1
OH
+
(1.0 eq.)
R2OH
NO2 O
O R1
Et3N (1.1 eq.), DMAP (0.1 eq.), rt
OR2
OR2
+ Me
(1.1 eq.)
Ester A R1COOH Ph(CH2)2 Ph(CH2)2 Ph(CH2)2 Ph(CH2)2
Ester B
R2OH
Y. %
Ester A / Ester B
95 98 92 94
>200 >200 >200 >200
PhCH2 THPO(CH2)5 CH2=CHCH2 C9H19C(CH3)2
Recently, Shiina and co-workers have reported a method using 2-methyl-6-nitrobenzoic anhydride (1). This esterification procedure is quite simple. Triethylamine, a catalytic amount of 4-dimethylaminopyridine, and 1 were dissolved in a solvent. The carboxylic acid was added and stirred, and finally a nearly equimolar amount of alcohol was added and the reaction stirred under room temperature. Through this reaction process, the desired ester (ester A) is obtained in high yields. The nitro group on the condensation reagent 1 promotes and facilitates the esterification under room temperature. The introduction of substituents at the two ortho positions of benzene ring controls the generation of byproduct (ester B). These two effects synergistically act to produce the desired ester in excellent yield and high purity. This reaction can also be applied to intramolecular esterification, and can afford lactones in high yields.
A1861
B1774
B1651 N
N N
N
N
O C
BF4 N(CH3)2
N
N
O
P N
CH3
108
N
N
N(CH3)2
N
N
N
N
O O
CH2 N C N CH2
O
N
PF6
O C
OP[N(CH3)2]3
B1213
O
B1658
PF6
N
B2771
CH3
B1657
CH3
O
F
N
PF6
Cl
N
O C
N(CH3)2
N(CH3)2 N(CH3)2
B1036 F
F
F
F
F
O
N P N O
N(CH3)2
B3604 O
CH3
N
O O
F
O C O F
F
F
N
Br
CH2CH3
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
BF4
BF4
Condensation & Active Esterification
B0832
C1124
C1298
CH3
O
C CH3 ClO4
O
CH2O C O N
CH2O C O N
O
O
Cl O Cl
CH3
CH3
C0119
C1988
O
Cl
N C N
N
O C
C0905
O
C0903
N
N
Cl
N
CH3
C0906
CH3 O
CH3
Cl
O
O
O
CH3
N
CH2O C O N
PF6
N(CH3)2 N(CH3)2
N N
C
C1651
O
N
O
O
C1408 C1639
Cl
N
N
Cl
C1131
N
O O
N
O C O C CH3 CH3
CH3
N
C1362
O
Br
O O
CH3
N
C1574
PF6
Cl
CH3
C1379
C1375
SO3 CH2CH3
N
BF4 O
N
I
Cl
N
CH3
C1957
CH3
N
Cl
CH3
N
N
CH3
C1242
O
CH3
N
SO3
D0254
N
D2919
CH3
N O
N
D1601
F NH2
CH3
CH3
D1450
SO3
CH3
CH3 N C N
N
OCH2CH3
D3293
O OH
OCH2CH3
O P
N
N
D1393
N
O
N C N
O
NC P OCH2CH3 OCH2CH3
BF4
D3262
C N
N
D2039
O
N
C Cl
D0436
CH2CH2N
CH3
P CH CN Bu
Cl
N
PF6
CH3
C0793
Bu Bu
PF6
N
C Cl
CH3
C1500
CH3
Cl
CH3
CH3
D2898
F
F
2
F F
D2899
OCH3 N CH3O
N
CH3
N
CH3CH2 N C N
CH3
N
(CH2)3N
CH3 CH3
N
CH3
CH3
N
CH3
N
H CH2
CH3
N
CH2OH
N C
N
. HCl
Cl
N CH2OH
N C
H CH2
CH3
O
D1771
D3683
D2038
D1720
SO3
CH3
N H
O
O
.
NH2
. CF3SO3
N
D1672
O
C N
P O
O 2
CH3
O
P O N3
S
CH3 OCH3
D2201
C1407
D1114
D2477
T1906
O O
O
O N
S O
O C O
N N
N
S
S
N
S
S
S
N N
O C O
N
O
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
109
Condensation & Active Esterification
D1662
D2222
O
E0363
E0219
F0239
O O
O2 N
NO2
N
N O C O N N
O
S S
N
OCH2CH3
F0726
O
H0468
H0528
H0395
CH3
N
CH3
F
CH3
CH3 N
O
CH3
PF6
N
H1304
N
O
O
OH
N
N OH
O
O
M0071
M0670 SO2Cl
CH3 CH3
SO2Cl
N
CH3 O
O
CH3
OH
M1439
NOH
M1186 SO3Na
O
. H2O
N
OH
SO3
H0623 B0249
O
N
F
CH3
CH2O C O N
SO3
O
N
O
CH2CH3
C OCH2CH3
O
F0225
O
N
O
CH3
CH3
SO2Cl
M1116
N
CH3
N0604
T0681
N0477 O
NO2 O
O
NO2
CH3
O
N O
Me Me
O C CF3
O
N
NO2
N
S N
O2N
N H
N
O
N
N
NO2
N0634
O0200
O0195
T0648
P1626 O
O
N CH3
N O
(CH3)2N
CH3 N
N
N C C N
O C BF4
O O
N(CH3)2
(CH3)2N P O P N(CH3)2 (CH3)2N
N CH3
Cl
F
F
Cl
Cl
F
F
CF3SO3
N(CH3)2 2BF4
CH3
P1042
P
O
SO2CH3
OSO2CH3
n
F
Cl
P1768
P1320 P1319 O
CH3SO3
NH3
O C CCl3 Cl
O CH2CH2CH3 P O CH3CH2CH2 O P P O CH2CH2CH3 O
P0939 O
Q0016
O N
C O C
O
N N
SO2Cl
N N
T1513
T1562
T2224 SO2Cl
O Cl
CH3
O
CCl3CHO C O N
T0340
N
N O C
SO2Cl
O
N(CH3)2 N(CH3)2
T1673
BF4
N H
T1413 N
N H
N
N
N
SO2
CH3
N
Cl
T1593 OH
C Cl
Cl
Cl
O CF3
O
C O C
Cl
OH Cl
110
N
T0389 O
N
N
N
O
CH3
N
T1985
O
CH3
CH3
T1017
Cl
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
CF3
Condensation & Active Esterification
T0459 CH3 CH3
T1122 SO2Cl
CH
CH
CH
CH3 CH3
CH3
SO3
CH3
CH3 CH3
N H
CH3 CH3
Product No. Product Name
Unit Size
A1861 B1774 B1651 B1657 B1658 B2771
O-(7-Azabenzotriazol-1-yl)-N,N,N ',N '-tetramethyluronium Tetrafluoroborate 1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate O-(Benzotriazol-1-yl)-N,N,N ',N '-tetramethyluronium Hexafluorophosphate O-(Benzotriazol-1-yl)-N,N,N ',N '-tetramethyluronium Tetrafluoroborate 1,3-Bis(2,2-dimethyl-1,3-dioxolan-4-ylmethyl)carbodiimide (This product is only
1g 5g 5g 5g 5g
5g 25g 25g 25g 25g
available for selling domestically in Japan)
B1213 B3604 B1036 B0832 C1124 C1298 C1574 C1362 C0119 C1988 C1131 C1408 C1639 C1651 C0905 C0903 C0906 C1379 C1375 C1957 C1500 C0793 D0436 D3262 C1242 D2039 D1393 D0254 D3293 D2919 D1601 D1450 D2898 D2899 D1771 D3683 D2038 D1720 D1672 D2201 C1407 D1114 D2477 T1906 D1662 D2222 E0363 E0219 F0239 F0225 F0726 H0468
Bis(2-oxo-3-oxazolidinyl)phosphinic Chloride Bis(pentafluorophenyl) Carbonate 2-Bromo-1-ethylpyridinium Tetrafluoroborate N-tert-Butyl-5-methylisoxazolium Perchlorate N-Carbobenzoxyoxysuccinimide Carbonic Acid 2-Bromobenzyl Succinimidyl Ester Carbonic Acid tert-Butyl 2,4,5-Trichlorophenyl Ester 2,2'-Carbonylbis(3,5-dioxo-4-methyl-1,2,4-oxadiazolidine) 1,1'-Carbonyldiimidazole O-(6-Chlorobenzotriazol-1-yl)-N,N,N ',N '-tetramethyluronium Hexafluorophosphate N-(2-Chlorobenzyloxycarbonyloxy)succinimide 2-Chloro-1,3-dimethylimidazolinium Chloride 2-Chloro-1,3-dimethylimidazolinium Chloride (ca. 25% in Dichloromethane) 2-Chloro-1,3-dimethylimidazolinium Hexafluorophosphate 2-Chloro-3-ethylbenzoxazolium Tetrafluoroborate 2-Chloro-1-methylpyridinium Iodide 2-Chloro-1-methylpyridinium p-Toluenesulfonate 1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium Hexafluorophosphate 1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium Tetrafluoroborate Chloro-N,N,N ',N '-tetramethylformamidinium Hexafluorophosphate Cyanomethylenetributylphosphorane 1-Cyclohexyl-3-(2-morpholinoethyl)carbodiimide Metho-p-toluenesulfonate N,N '-Dicyclohexylcarbodiimide 3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one Diethyl Cyanophosphonate 3,4-Dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine 3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one N,N '-Diisopropylcarbodiimide Dimesitylammonium Pentafluorobenzenesulfonate 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Chloride 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride 4-Dimethylaminopyridine (4R,5R)-1,3-Dimethyl-4,5-diphenyl-2-[(S)-1-benzyl-2-hydroxyethylimino]imidazolidine (4S,5S)-1,3-Dimethyl-4,5-diphenyl-2-[(R)-1-benzyl-2-hydroxyethylimino]imidazolidine 2,6-Dimethylpyridinium p-Toluenesulfonate Diphenylammonium Trifluoromethanesulfonate Diphenyl (2,3-Dihydro-2-thioxo-3-benzoxazolyl)phosphonate N,N-Diphenyl-4-methoxybenzamide Diphenylphosphoryl Azide 4,6-Diphenylthieno[3,4-d]-1,3-dioxol-2-one 5,5-Dioxide Di-2-pyridyl Carbonate 2,2'-Dipyridyl Disulfide 4,4'-Dipyridyl Disulfide O,O '-Di-2-pyridyl Thiocarbonate Di(N-succinimidyl) Carbonate 2,2'-Dithiobis(5-nitropyridine) 1-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline N-Ethyl-5-phenylisoxazolium-3'-sulfonate N-[(9H-Fluoren-9-ylmethoxy)carbonyloxy]succinimide 2-Fluoro-1-methylpyridinium p-Toluenesulfonate Fluoro-N,N,N ',N '-tetramethylformamidinium Hexafluorophosphate 1-Hydroxybenzotriazole Monohydrate
1g 5g
5g 25g 5g 25g 5g 250g 10g 5g 5g 250g 5g 10g 25g 25g 25g 25g 500g 25g 25g 5g 5g 25g 25g 500g 5g 25g 25g 25g 250g 5g 25g 250g 500g 100mg 100mg 25g 25g 25g 5g 250g 5g 5g 250g 25g 1g 25g 5g 25g 1g 25g 25g 5g 500g
5g 1g 25g
25g 1g 5g 5g 5g 25g 5g
1g
5g
1g 5g 5g 25g 5g 10g 5g 25g 1g 5g 25g 25g
1g
5g 5g
5g
25g
5g
25g 5g 5g
5g 5g 1g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
111
Condensation & Active Esterification
Product No. Product Name H0528 H0395 H0623 B0249 H1304 M1186 M0071 M0670 M1439 M1116 N0604 T0681 N0477 N0634 O0200 O0195 T0648 P1626 P1042 P1320
N-Hydroxy-5-norbornene-2,3-dicarboximide N-Hydroxyphthalimide N-Hydroxysuccinimide N-Hydroxysuccinimide N-Hydroxysulfosuccinimide Sodium Salt 2,4-Mesitylenedisulfonyl Dichloride 2-Mesitylenesulfonyl Chloride 9-Methyl-3,4-dihydro-2H-pyrido[1,2-a]pyrimidin-2-one 2-Methyl-6-nitrobenzoic Anhydride 6-Methyl-2H-pyrido[1,2-a]pyrimidin-2-one 1-(4-Nitrobenzenesulfonyl)-1H-1,2,4-triazole 4-Nitrophenyl Trifluoroacetate 3-Nitro-1,2,4-triazole 2-(5-Norbornene-2,3-dicarboximido)-1,1,3,3-tetramethyluronium Tetrafluoroborate 1,1'-Oxalyldiimidazole μ-Oxo-bis[tris(dimethylamino)phosphonium] Bis(tetrafluoroborate) (=Bates' Reagent) Pentachlorophenyl Trichloroacetate Pentafluoroanilinium Trifluoromethanesulfonate Phosphorus Pentoxide - Methanesulfonic Acid Propylphosphonic Acid Anhydride (Cyclic Trimer) (48% in N,N-Dimethylformamide,
Unit Size 25g 25g 25g 200mg 5g 25g 1g
5g
5g 5g 1g
1g
5g 25g
ca. 1.6mol/L)
P1319 P1768 P0939 Q0016 T1513 T1562 T2224 T1017 T1985 T0340 T1673 T1413 T0389 T1593 T0459 T1122
Propylphosphonic Acid Anhydride (Cyclic Trimer) (50% in Ethyl Acetate, ca. 1.7mol/L) 3-Pyridinecarboxylic Anhydride 4-Pyrrolidinopyridine Quinoline-8-sulfonyl Chloride N-(1,2,2,2-Tetrachloroethoxycarbonyloxy)succinimide 2,4,5,6-Tetramethylbenzenedisulfonyl Dichloride N,N,N ',N '-Tetramethyl-O-(N-succinimidyl)uronium Tetrafluoroborate 1H-Tetrazole 1-(p-Toluenesulfonyl)imidazole 1,2,4-Triazole 3H-1,2,3-Triazolo[4,5-b]pyridin-3-ol 2,4,6-Trichlorobenzoyl Chloride 2,4,5-Trichlorophenol 4-Trifluoromethylbenzoic Anhydride 2,4,6-Triisopropylbenzenesulfonyl Chloride 2,4,6-Trimethylpyridinium p-Toluenesulfonate
1g 5g 5g
1g
1g 5g 5g 25g 5g 5g 25g 25g
References 1) 2) 3) 4) 5) 6) 7)
112
I. Shiina, R. Ibuka, M. Kubota, . 2002, 286. I. Shiina, M. Kubota, R. Ibuka, . 2002, , 7535. J. Tian, N. Yamagiwa, S. Matsunaga, M. Shibasaki, . 2003, , 3021. I. Shiina, H. Oshiumi, M. Hashizume, Y. Yamai, R. Ibuka, . 2004, 45, 543. I. Shiina, M. Kubota, H. Oshiumi, M. Hashizume, . 2004, , 1822. I. Shiina, . 2007, , 239. Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 2003 335731, 2003.
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
250g 500g 500g 25g 1g 25g 500g 25g 25g 5g 5g 25g 5g 25g 5g 1g 25g 25g 500g 25g 25g 5g 25g 25g 10g 5g 5g 25g 25g 500g 25g 25g 500g 10g 500g 25g
Glycosylation
Glycosylation It has been revealed that the oligosaccharide is an important factor in many areas of life processes, embryonic growth, differentiation, aging, immunity and carcinogenesis. Many researches have been conducted to understand the functions in biological systems and structure-activity relationship of oligosaccharides. For the structure-based studies, it is necessary to synthesize oligosaccharides with confirmed structure so as to evaluate their activity. Throughout the synthesis of oligosaccharides, glycosylation, protection and deprotection processes are repeated for every glycosidic linkage formed. Thus, in order to synthesize oligosaccharides effectively, the glycosyl donor and acceptor, as well as the protecting agents are vitally important. For this reason, there is much research activity in finding glycosyl donors and acceptors with suitable properties. The glucose derivative 1, with thioformimidate as a leaving group, was developed by Mukaiyama and his co-workers.1) This reagent is a glycosyl donor with high reactivity and stability. 1 is activated with a catalytic amount of TfOH in the presence of MS5A and reacts with a glycosyl acceptor 2 to provide a disaccharide 3 in a quantitative yield. Furthermore, by choosing the appropriate solvents, αor β-glycosides can be obtained selectively. The glycosyl acceptors with a fluorine atom or an ethylthio group at 1-position were also used and the resulting disaccharides can also be used as glycosyl donors. OH O
R'O OR' BnO BnO
OBn O BnO
X 2
R'O
Acceptor (1.0 eq.)
NR O C SCH2R
1
OBn O
BnO BnO
O BnO R'O OR' 3
TfOH (5 mol%), MS 5A (3 g/mmol), Solvent
R=p-trifluoromethylphenyl
Acceptor
Entry 1 2
R'
X
Benzoyl EtS Benzyl F
O X R'O Yield % (α/β) EtCN
t-BuOMe
95 (98/11) 98 (2/98) 97 (87/13) 81 (2/98)
In addition, the utility of -methoxyphenyl glycosides has been reported.2) The -methoxyphenyl group is a useful anomeric protective group which is stable under most of the conditions used in oligosaccharide synthesis. It is removed selectively by treatment with 2,3-dichloro-5,6-dicyano- -benzoquinone and ammonium cerium(IV) nitrate, to give the corresponding hemiacetals. Also the -methoxyphenyl glycosides are converted in one step into the corresponding glycosyl halides and thiophenyl glycosides in high yields and can be used as glycosyl donors. O
O
phosphite
Br / Cl O O
OCH3
O
O imidate
OH O
O F
SR
The followings are glycosyl donors in which the anomeric position is activated, including 1, -methoxyphenyl glycosides, glycosyl acceptors and activating agents that can be obtained from TCI. TCI is pleased to supply these reagents for your needs in the research of oligosaccharides and related studies.
T2295 AcO
Glycosyl Donors
Imidate Sugars
T2491 OAc O
AcO AcO
NH O C CCl3
AcO AcO
OAc O
NH O C CCl3
OAc
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
113
Glycosylation
T1991
T1999 OBz O
BzO BzO
N
BzO
T2615
OBn O
BnO BnO
CF3
CF3
N
BnO
O S CH2
T2695
AcO
O S CH2
CF3
NH
OAc O
CF3
O C CCl3
OAc O
AcO AcO
NH O C CCl3
O
N
O
OAc
Product No. Product No.
Unit Size
2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-Trichloroacetimidate 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl 2,2,2-Trichloroacetimidate 2,3,4,6-Tetra-O-benzoyl-α-D-glucopyranosyl p-TrifluoromethylbenzylthioN-(p-trifluoromethylphenyl)formimidate 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl p-TrifluoromethylbenzylthioN-(p-trifluoromethylphenyl)formimidate 2,3,4-Tri-O-acetyl-β-L-arabinopyranosyl 2,2,2-Trichloroacetimidate 3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl 2,2,2-Trichloroacetimidate
T2295 T2491 T1991 T1999 T2695 T2615
I0328
M1706
HO
Thioglycosides
M1501
OH O
HO
S
CH3
HO
M1649
AcO
SCH3 N
CH3
Ph
O
O N
SPh Bn
O O HO
SCH3 OAc
O OAc
SPh
CH3 BnO
OH O
SPh HO
P1680
AcO
SPh NH C OCH2CCl3
P1736 AcO
OBn O
BnO
SPh OBn
OAc O
O
AcO SPh
OAc
SCH3
P1660
O
SPh OAc
P1476 OAc O SPh
OAc O
AcO AcO
SPh AcO
OAc
AcO
SPh OBn
AcO
AcO
OBn O
O
OBn
P1642 OAc O
BnO
SCH3 OBn
O
O
P1679
OAc O
AcO AcO
AcO
P1477
HO
O
BnO
O
1g
OAc
P1643 HO
O
COOCH3 O
M1628
AcO
P1475
O
COOCH3
O
SCH3
Ph
O
AcO AcO
200mg
M1682
AcO
M1626
O
P1762
SPh
AcO AcHN
5g 5g
200mg 1g Price on request Price on request
OAc O
AcO AcO
OAc O
AcO AcO
OAc
AcO
CH3
M1759
1g 1g
P1866 OAc O SPh NH C OCH2CCl3
AcO AcO
OAc O SPh NH C OCH2CCl3
O
P1842
CH3 BnO
114
O
SPh OBn
OBn
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
O
Glycosylation
Product No. Product No. I0328 M1706
Unit Size
Isopropyl 1-Thio-β-D-galactopyranoside Methyl 5-Acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-S-phenyl-2-thio-D-glyceroD-galacto-2-nonulopyranosylonate Methyl (Phenyl 2,3,4-Tri-O-acetyl-1-thio-β-D-glucopyranosid)uronate Methyl 2,3,4,6-Tetra-O-acetyl-1-thio-β-D-glucopyranoside Methyl 2,3,4,6-Tetra-O-acetyl-1-thio-α-D-mannopyranoside (contains ca. 5% β-isomer) Methyl 3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside Methyl 2,3,4-Tri-O-acetyl-1-thio-β-L-fucopyranoside Methyl 2,3,4-Tri-O-benzyl-1-thio-β-L-fucopyranoside Phenyl 3-O-Allyl-2,4,6-tri-O-benzyl-1-thio-β-D-galactopyranoside Phenyl N-Benzyl-2-amino-4,6-O-benzylidene-2-N,3-O-carbonyl-2-deoxy-1-thioβ-D-glucopyranoside Phenyl 4,6-O-Benzylidene-1-thio-β-D-glucopyranoside Phenyl 2-Deoxy-1-thio-2-(2,2,2-trichloroethoxyformamido)-β-D-galactopyranoside Phenyl 2,3,4,6-Tetra-O-acetyl-1-thio-β-D-galactopyranoside Phenyl 2,3,4,6-Tetra-O-acetyl-1-thio-β-D-glucopyranoside Phenyl 2,3,4,6-Tetra-O-benzyl-1-thio-β-D-galactopyranoside Phenyl 2,4,6-Tri-O-acetyl-3-O-allyl-1-thio-β-D-galactopyranoside Phenyl 2,4,6-Tri-O-acetyl-3-O-allyl-1-thio-β-D-glucopyranoside Phenyl 3,4,6-Tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxyformamido)β-D-galactopyranoside Phenyl 3,4,6-Tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxyformamido)β-D-glucopyranoside Phenyl 2,3,4-Tri-O-benzyl-1-thio-β-L-fucopyranoside
M1759 M1682 M1501 M1649 M1626 M1628 P1660 P1762 P1475 P1643 P1477 P1476 P1679 P1680 P1736 P1642 P1866 P1842
A1416
Halogeno Sugars
T1971
BnO BnO
T1961 OAc O
AcO AcO
AcHN
AcO AcO
OBn O BnO
F
OAc O AcO
Cl
T1922
T1995
BnO BnO
BnO
BnO BnO
AcO
1g 1g 1g 5g 5g 1g 5g 1g 5g 1g Price on request 1g 5g Price on request 5g 25g 5g 25g 1g Price on request 1g Price on request
AcO
F
F
OBn O
RO RO F
OR O F O
R=
C C(CH3)3
Unit Size
2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl Chloride 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl Bromide (stabilized with CaCO3) 2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl Fluoride 2,3,4,6-Tetra-O-acetyl-D-mannopyranosyl Fluoride 2,3,4,6-Tetra-O-benzyl-D-glucopyranosyl Fluoride 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl Fluoride 2,3,4,6-Tetra-O-benzyl-β-D-glucopyranosyl Fluoride 2,3,4,6-Tetra-O-pivaloyl-D-mannopyranosyl Fluoride
R0067
R0080
BzO
OAc
OBz OBz
BzO
1g
5g 5g 1g 1g 5g 500mg 500mg 500mg 1g
R0066
OBz OBz O
O
Others
OAc O
AcO AcO
Product No. Product No. A1416 T1961 T1995 T2567 T1971 T1922 T1923 T2568
5g 5g
1g
T2568
BnO
F
OAc O
Br
RO
OBn O
5g
T2567
AcO AcO
T1923
1g
OAc
T2197
AcO
OAc O
BnO BnO
OBn O BnO
O O P N(CH3)2
OAc OAc
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
N(CH3)2
115
Glycosylation
Product No. Product No.
Unit Size
β-D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate β-L-Ribofuranose 1-Acetate 2,3,5-Tribenzoate Tetra-O-acetyl-β-D-ribofuranose 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl N,N,N ',N '-Tetramethylphosphorodiamidate
R0067 R0080 R0066 T2197
5g
25g 1g 25g
5g
5g
(ca. 20% in Benzene)
B0041
B2440
B3664 SF3
SH CH3OCH2CH2
Reagents for Glycosyl Donor Synthesis D1868
N S
F
F
CH3 C CH3
M1573
P1243 SF3
CH3
F
CH3
F
S
N
CH2
HBr
P Cl
OH
O
T1308
T0372
CH3
CH3
CH3
H0182
F
Et
N S
CH3OCH2CH2
D2159
Et
CH3
F
S
S
P
P CH3
T2638
T2547
Cl
CCl3CN
CF3
Cl
C N
CF3
OCH3
C N
CH3 CH3
Product No. Product No. B0041 B2440 B3664 D1868 D2159 H0182 M1573 P1243 T1308 T0372 T2638 T2547
Unit Size
Benzenethiol Bis(2-methoxyethyl)aminosulfur Trifluoride 4-tert-Butyl-2,6-dimethylphenylsulfur Trifluoride (Diethylamino)sulfur Trifluoride [Fluorinating Reagent] Dimethylthiophosphinoyl Chloride Hydrogen Bromide (30% in Acetic Acid, ca. 5.1mol/L) [for Peptide research] Morpholinosulfur Trifluoride 4-Penten-1-ol Tetramethyldiphosphine Disulfide Trichloroacetonitrile 2,2,2-Trifluoro-N-(4-methoxyphenyl)acetimidoyl Chloride 2,2,2-Trifluoro-N-phenylacetimidoyl Chloride
25ml 5g 5g
500ml 25g 5g 100g 5g 500g 5g 250ml 5g 500g 5g 5g
25g 1g 25g 1g 25ml 25g
M1620
M1590 Ph
Ph
O O
O O
Galactose
-Methoxyphenyl Glycosides & Related Reagents M1633
O O
O O
O
OCH3
O
OBn
CH3 O
M1596
M1477
M1588
O CH3 CH3 CH3
O
OBn O
O
CH3 O
OBn
OCH3
CH3
O
AcO
O O
O
O
OCH3
O
BnO
OAc O
AcO
O OAc
OCH3
OBn O
BnO
O
OCH3
OBn
CH3 O
116
OCH3
O
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Glycosylation
Product No. Product No. M1620 M1590 M1633 M1596 M1477 M1588
Unit Size
4-Methoxyphenyl 3-O-Allyl-2-O-benzyl-4,6-O-benzylidene-β-D-galactopyranoside 4-Methoxyphenyl 3-O-Allyl-4,6-O-benzylidene-2-O-(4-methylbenzoyl)-β-D-galactopyranoside 4-Methoxyphenyl 2,6-Di-O-benzyl-3,4-O-isopropylidene-β-D-galactopyranoside 4-Methoxyphenyl 3,4-O-Isopropylidene-2,6-bis-O-(4-methylbenzoyl)-β-D-galactopyranoside 4-Methoxyphenyl 2,3,4,6-Tetra-O-acetyl-β-D-galactopyranoside 4-Methoxyphenyl 2,3,4,6-Tetra-O-benzyl-β-D-galactopyranoside
1g 1g 1g 1g 25g 5g
5g
M1643 Ph O O
Galactosamine
O O
O N3
OCH3
Product No. Product No. M1643
Unit Size
4-Methoxyphenyl 3-O-Allyl-2-azido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside
M1630
Glucose
M1642
OAc O
AcO AcO
1g
O
OCH3
OAc O
AcO BnO
O
OAc
OCH3
OAc
Product No. Product No. M1630 M1642
Unit Size
4-Methoxyphenyl 2,3,4,6-Tetra-O-acetyl-β-D-glucopyanoside 4-Methoxyphenyl 2,4,6-Tri-O-acetyl-3-O-benzyl-β-D-glucopyranoside
M1834
M1598
OBn O
AcO BnO
Ph
O O
Glucosamine
M1638
N
O
OCH3
Ph
O O
O O
O
OCH3
5g 5g
1g
M1609
O O O O
O O N O
Ph
OCH3
O O BnO
O O O
N
OCH3
O
N3
M1480 OAc O
AcO AcO
O O
N
OCH3
O
Product No. Product No. M1834 M1638 M1598 M1609 M1480
4-Methoxyphenyl 4-O-Acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 4-Methoxyphenyl 3-O-Allyl-2-azido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside 4-Methoxyphenyl 3-O-Allyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranoside 4-Methoxyphenyl 3-O-Benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimidoβ-D-glucopyranoside 4-Methoxyphenyl 3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside
Unit Size 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 1g 5g 1g 5g
117
Glycosylation
M1647 AcO
OAc O
AcO AcO
Mannose
O
OCH3
Product No. Product No.
Unit Size
4-Methoxyphenyl 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranoside
M1647
G0330
M1694
5g
G0309
G0311
Ph AcO
O AcO
Disaccharides
OAc O
AcO
O O O
O
OAc
G0299
AcO AcO O
OAc BnO O O N O
AcO OCH3
AcO O
OCH3
OBn
OAc
AcO O AcHN AcO
O OAc AcO
O
OCH3
AcO
O
O O
OAc
OAc
M1763
COOCH3 O BzO BnO
OAc Ph O
AcO
O O N3
OCH3
O OAc
O O
O O O N O
OCH3
O
O OBz
N0816
OAc AcO COOCH3 AcO O O HN BzO AcO O O BnO O OBz
OCH3
OCH3
AcO
OBz O
O OBz
OCH3
Unit Size
Gal[2346Ac]β(1-3)GalN3[46Bzd]-β-MP Gal[2346Ac]β(1-4)Glc[236Ac]-β-MP Gal[2346Ac]β(1-3)GlcN3[46Bzd]-β-MP Gal[2346Ac]β(1-3)GlcNPhth[46Bzd]-β-MP GlcNPhth[346Ac]β(1-3)Gal[246Bn]-β-MP Neu5Ac[1Me,4789Ac]α(2-6)Gal[24Bz,3Bn]-β-MP Neu5GcAc[1Me,4789Ac]α(2-6)Gal[24Bz,3Bn]-β-MP Neu5GcAc[1Me,4789Ac]α(2-3)Gal[246Bz]-β-MP
C1806
BzO OAc CH3OOC AcO O O HN AcO O
AcO
AcO
Product No. Product No. G0330 M1694 G0309 G0311 G0299 M1761 M1763 N0816
OAc Ph O
AcO
OAc O
N3
M1761 OBn O
AcO OAc O
Price on request Price on request Price on request 1g 5g Price on request 200mg 200mg Price on request
D1070 O NC
Deprotecting Reagents
NC
118
Cl O
Product No. Product No. C1806 D1070
Cl
(NH4)2Ce(NO3)6
Ceric Ammonium Nitrate 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone
Unit Size 50g 25g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
500g 250g
Glycosylation
M1589
M1482
Ph OH
O O
Galactose
Glycosyl Acceptors
OH O
O
O O
O
O
OCH3
O
OCH3
HO
OCH3
HO
M1725
M1710
M1597
HO
O
BnO
O
HO
O HO
O
O
OCH3
HO
CH3 CH3 CH3
O O
CH3
HO
OBn
O
OCH3
HO
O
OBz O
BzO
OCH3
BzO
OBn
OBn
OCH3
Unit Size
4-Methoxyphenyl 3-O-Allyl-4,6-O-benzylidene-β-D-galactopyranoside 4-Methoxyphenyl 3-O-Allyl-β-D-galactopyranoside 4-Methoxyphenyl 3-O-Benzyl-β-D-galactopyranoside 4-Methoxyphenyl 4,6-O-Benzylidene-β-D-galactopyranoside 4-Methoxyphenyl 2,6-Bis-O-(4-methylbenzoyl)-β-D-galactopyranoside 4-Methoxyphenyl 2,6-Di-O-benzyl-β-D-galactopyranoside 4-Methoxyphenyl 3,4-O-Isopropylidene-β-D-galactopyranoside 4-Methoxyphenyl 3,4-O-Isopropylidene-6-O-(4-methylbenzoyl)-β-D-galactopyranoside 4-Methoxyphenyl 2,3,6-Tri-O-benzyl-β-D-galactopyranoside 4-Methoxyphenyl 2,4,6-Tri-O-benzyl-β-D-galactopyranoside Methyl 2,3,6-Tri-O-benzoyl-α-D-galactopyranoside
A1833
A1832
Ph
1g 5g Price on request Price on request 1g 1g 1g 1g Price on request 1g 5g 25g 250g
P1643
Ph O
O
HO
O
O
OH O
O
O
Galactosamine
HO
N3 O
HO
N3 O
O
HO
OC(CH3)3 HN
O
OC(CH3)3
CH3 HN
Fmoc
SPh NH C OCH2CCl3
O
Fmoc
Product No. Product No. A1833 A1832 P1643
Unit Size
O-(2-Azido-4,6-O-benzylidene-2-deoxy-α-D-galactopyranosyl)-N-[(9H-fluoren9-ylmethoxy)carbonyl]-L-serine tert-Butyl Ester O-(2-Azido-4,6-O-benzylidene-2-deoxy-α-D-galactopyranosyl)-N-[(9H-fluoren9-ylmethoxy)carbonyl]-L-threonine tert-Butyl Ester Phenyl 2-Deoxy-1-thio-2-(2,2,2-trichloroethoxyformamido)-β-D-galactopyranoside D1949
I0400
CH3
O
CH3
O
Price on request Price on request Price on request
M1640
M1641
HO HO
OH
OH O
O
Glucose
OH
OH
Product No. Product No. M1589 M1482 M1725 M1710 M1597 M1634 M1593 M1594 M2104 M1592 M1933
O O
M1933
O
O
OCH3
OCH3
CH3
BnO
OBn O
OH
CH3
O OBn
M1592
BnO
O O
OBn O
HO
O
M2104 O
O
OCH3
O
HO
M1594
HO O
OCH3
HO
M1593
CH3 O
OH
O
OH O
M1634
O
Ph
Ph
O
O O
CH3 CH3
O
O O BnO
O O OH
CH3
OCH3
HO BnO
OH O O
OCH3
OH
CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
119
Glycosylation
M1125 Ph
M1487
O O HO
O HO
M1488 OH O
BzO BzO
BzO
OCH3
P1475 OH O
BnO BnO
BnO
OCH3
Ph
O O HO
O SPh HO
OCH3
Product No. Product No.
Unit Size
1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose 1,2-O-Isopropylidene-α-D-glucofuranose 4-Methoxyphenyl 3-O-Benzyl-4,6-O-benzylidene-β-D-glucopyranoside 4-Methoxyphenyl 3-O-Benzyl-β-D-glucopyranoside Methyl 4,6-O-Benzylidene-α-D-glucopyranoside Methyl 2,3,4-Tri-O-benzoyl-α-D-glucopyranoside Methyl 2,3,4-Tri-O-benzyl-α-D-glucopyranoside Phenyl 4,6-O-Benzylidene-1-thio-β-D-glucopyranoside
D1949 I0400 M1640 M1641 M1125 M1487 M1488 P1475
A1811
Ph
O O HO
Glucosamine
N3
M1479 OH O
Ph
O O
O
N
OCH3
O O O
O
Ph
O
OCH3
N
OCH3
O
O O HO
O O
M1617
O O
OCH3
HO BnO
OBn O O
N
O
OCH3
HO HO
OH O
OPh
Product No. Product No.
Unit Size
2-Acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranosyl Azide 4-Methoxyphenyl 2-Amino-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside 4-Methoxyphenyl 2-Azido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside 4-Methoxyphenyl 2-Azido-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside 4-Methoxyphenyl 3-O-Benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 4-Methoxyphenyl 4,6-O-Benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranoside 4-Methoxyphenyl 3,6-Di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside Phenyl N-Acetyl-α-D-glucosaminide
1g 1g 1g
5g 5g 5g 1g Price on request 5g 1g 100mg
T1459
AcO
Mannose
120
AcO AcO
OCH3
N3
AcHN
A1811 M1616 M1637 M1617 M1610 M1479 M1615 P0130
25g 25g 5g 1g 25g 5g 1g 5g
P0130 OBn O
HO BnO
5g 1g
N3
NH2
M1615
O O HO
1g
M1637
OBn O
HO BnO
NHAc
M1610
HO BnO
M1616
10g
HO O OAc
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Glycosylation
Product No. Product No. T1459
Unit Size
1,3,4,6-Tetra-O-acetyl-β-D-mannopyranose
M1686
HO
Disaccharides
HO
1g
M1726
HO
OBn O O OBn BnO
OBn O O
M1727
BnO
OBn O
BnO
OCH3
OBn
O OBnBnO
OBn O O
HO
OCH3
OBn
OBn O
OBn O
O OBn BnO
O
OCH3
OBn
Product No. Product No.
Unit Size
Gal[26Bn]β(1-4)Glc[236Bn]-β-MP Gal[236Bn]β(1-4)Glc[236Bn]-β-MP Gal[246Bn]β(1-4)Glc[236Bn]-β-MP
M1686 M1726 M1727
5g
Price on request 1g 5g Price on request
B0527
B0656
C0903 O
BF3
Activating Agents
.
CH3
O
N Br
CH3
N
O
T1292
H0914
I0074
Cl
I
CH3
T2029
T1331
O CF3
Cu2
S O O
O
O
O Cl
Hf
N
Cl
I
CF3
CH3O S CF3
S OAg O
O
2
O
T0751
T0871
T1173
O CF3SO3H
CF3
CH3
S O Si CH3 O
Z0007
C
BF4
Product No. Product No. B0527 B0656 C0903 T1292 H0914 I0074 T2029 T1331 T0751 T0871 T1173 Z0007
Cl
Zr
Cl
CH3
Boron Trifluoride - Ethyl Ether Complex N-Bromosuccinimide 2-Chloro-1-methylpyridinium Iodide Copper(II) Trifluoromethanesulfonate Hafnocene Dichloride N-Iodosuccinimide Methyl Trifluoromethanesulfonate Silver Trifluoromethanesulfonate Trifluoromethanesulfonic Acid Trimethylsilyl Trifluoromethanesulfonate [Trimethylsilylating Agent] Triphenylmethylium Tetrafluoroborate Zirconocene Dichloride
Unit Size 25g
1g 5g
10g 5g
25ml 100g 25g 5g 5g 25g 5g 10g 25g 25g 5g 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500ml 500g 500g 25g 25g 100g 25g 25g 250g 250g 25g 25g
121
Glycosylation
Enzyme-related Reagents Enzyme Product No. Product No.
Unit Size
A1844
endo-α-N-Acetylgalactosaminidase (=Endo-α) Recombinant: from Bifidobacterium longum
A1651
endo-β-N-Acetylglucosaminidase (=Endo-M) Recombinant: from Mucor hiemalis expressed in
1vial
expressed in Escherichia coli
1vial
Candida boidinii [Purity: single band by SDS-PAGE(85KDa)]
A1614 OH O
HO HO
Enzyme Substrates
D3690
AcHN
H N
COOH O
NHBoc
OH OH COOH HO HO O O AcHN O O OH HO HO OH
G0297 OH O
O NHAc HO HO O HO O HO O HO OH HO O OH COOH HO HO OHOH O O AcHN O O O O HO HO OH OH NHAc
O OH O HO O
R=
NHAc O O HO OH H N
OH O
R
NHAc
COOH O NH O S O
Me
N
HO HO
OH O AcHN
HN H
H N
NH H S
O
Me
S0523 HO
OH
HO AcHN
O HO
CO2Na HO O HO
O OH
O HO
OH O O AcHN HO HO HO
O HO O HO
OH
HO AcHN
CO2Na HO O O
HO
HO
HO HO HO HO O O O HO OH AcHN
NH2
Lys O
Val OH O
HO O
O O
NHAc O HO
O OH
OH O
Ala
Asn NHAc Lys Thr COOH
Product No. Product No. A1614 D3690 G0297 S0523
Unit Size
N ω-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-Nα-(tert-butoxycarbonyl)-L-asparagine DNS-SGN N-GlcNAc-Biotin Sialylglycopeptide
100mg 1mg 50mg 10mg
References 1) T. Mukaiyama, H. Chiba, S. Funasaka, . 2002, 392; H. Chiba, S. Funasaka, K. Kiyota, T. Mukaiyama, . 2002, 746; H. Chiba, T. Mukaiyama, . 2003, , 172; H. Chiba, S. Funasaka, T. Mukaiyama, . 2003, , 1629. 2) M. Mori, Y. Ito, T. Ogawa, . 1989, , 131; Y. Matsuzaki, Y. Ito, T. Ogawa, . 1992, , 4025; A. Dan, Y. Ito, T. Ogawa, . 1995, , 4680; C. Murakata, T. Ogawa, . 1992, , 95; H. Kuyama, T. Nukada, Y. Nakahara, T. Ogawa, . 1993, , 2171; Z. Zhang, G. Magnusson, . 1996, , 41; H. Ando, Y. Koike, H. Ishida, M. Kiso, . 2003, , 6883.
122
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Phosphorylation
Phosphorylation The phosphorylation reaction is an important reaction in organic synthesis, especially in DNA or RNA synthesis where nucleotides are made by adding phosphate groups to nucleosides. Various reagents and methods of phosphorylation have been developed. For example, the phosphorylation methods include the DCC method by Khorana ., the phosphotriester method and the phosphite method by Letsinger . and the amidite method by Caruthers . etc. They are utilized depending on each purpose. This section below shows the typical reagents employed for phosphorylation.
C0978
C1210
C1215
NCCH2CH2O P O O
O
Ba2+
O
. xH2O
P
C0977
O
O
P
O
O O
Cl
Cl
C2228 O P
C0976
O
O
O
C1250
D2624
P
O P O
Cl
Cl Cl
Cl
D0624
D0764
Cl Cl
OCH2CH2CN (CH3)2CH (CH3)2CH
N
P
N
BnO
CH(CH3)2
BnO
S
S
CH(CH3)2 P N
CH(CH3)2
Cl CH(CH3)2
CH3O P Cl
P OCH2CH3
OCH3
OCH2CH3
Cl
D1059
D2883
M0905
M0904
P0209 O
O
O
Cl
O P O Cl
O
P O P Cl Cl
Cl
CH3O P
Cl
O
Cl
CH3O P
O P Cl
Cl Cl
Cl
P1223
O
O
CH2O P O P OCH2 2
2
Product No. Product No. C0978 C1210 C1215 C1250 C0976 C0977 C2228 D2624 D0624 D0764 D1059 D2883 M0905 M0904 P0209 P1223
Barium 2-Cyanoethylphosphate Hydrate 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one 2-Chloro-1,3,2-dioxaphospholane 2-Chloro-2-oxo-1,3,2-dioxaphospholane 2-Chlorophenyl Phosphorodichloridate 4-Chlorophenyl Phosphorodichloridate 2-Cyanoethyl N,N,N ',N '-Tetraisopropylphosphordiamidite Dibenzyl N,N-Diisopropylphosphoramidite Diethyl Chlorothiophosphate Dimethyl Chlorothiophosphate Diphenyl Chlorophosphate Diphosphoryl Chloride Methyl Dichlorophosphite Methyl Phosphorodichloridate Phenyl Dichlorophosphate Tetrabenzyl Pyrophosphate
Unit Size 5g 5g 5g 5g 5g 1g 25g 25g 25g
5g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 25g 25g 25g 25g 25g 5g 5g 500g 500g 500g 25g 10g 25g 500g 1g
123
Amination
Amination The Gabriel reagent is widely used as a nucleophilic aminating agent since its reactivity is reliable and its handling is easy.1) A variety of aminating agents analogous to the Gabriel reagent have been reported. The potassium salt of imide 1 reacts with alkyl halide to give imide 2. 2 is treated with base or acid to give either -Boc-amine 3 or -methoxycarbonylamine 4, respectively. Moreover, 1 also serves as an acid nucleophile in the Mitsunobu reaction to allow for the conversion of hydroxy groups to amino groups. Therefore, 1 is a useful reagent to give monoprotected amines.2) O O
NaOH aq. / MeOH
t-BuO C
NH , KOH
MeO C O
R CH2Br
O
1
R CH2N
R CH2N
C Ot-Bu H
C Ot-Bu
3
C OMe O
CF3CO2H
2
R CH2N
H C OMe O
4
Fukuyama and co-workers have demonstrated various reactions using the -substituted sulfonamide 5.3) Smooth reactions of 5 occur with alkyl halides under basic conditions and alcohols under Mitsunobu conditions to provide -nitrobenzenesulfonyl ( -Ns) amines 6. The various -Ns amines (Alloc, Boc, Cbz) 6 obtained from these reactions can be selectively deprotected, under the appropriate conditions, to afford the monoprotected amines 7 and 8. Furthermore, 7 can be converted to the primary amine in high yields via a second deprotection. 8 can be converted to the secondary amine in high yields by repeating the alkylation and deprotection process.4) RS -
R1 SO2NHY a)
NO2
SO2NHR1
NO2
NO2
b)
i) c) ii) RS -
5
6
Y = Alloc 5a Boc 5b Cbz 5c
R1NH2
7
N Y
O2S
b)
R1NHY
R1NHR2
8
a) R1X, K2CO3, DMF or R1OH, DEAD, PPh3
b) When 5a Pd(PPh3)4, pyrrolidine 5b TFA 5c BCl3
c) R2X, K2CO3, DMF or R2OH, DEAD, PPh3
On the other hand, acetoxime -(2,4,6-trimethylphenyl)sulfonate 9 has been reported as a useful electrophilic aminating agent. 9 reacts with Grignard reagents in the presence of a catalytic amount of magnesium chloride to afford primary amines in good yields.5)
Me
R MgBr
A1441
A1137 O
S O N C O CH3
124
R N C
A1632 CH3 O
CH3
Me O Me S O N C Me O Me 9 , MgCl2 (cat.)
CH3 CH3
SO2NH C OCH2CH NO2
CH2
Me
Hydrolysis
R NH2
Me
A1341 N
N N
B2303 S CH2N3
O SO2NH
C OtBu
NO2
NH2
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Amination
B1648
B2857
I0510
C1757
I0497
O O
SO2NH C OtBu O CH3 H P O N C O C CH3
O
O CH3O 2
CH3
O
SO2NH
C OCH2
NO2
CH3O C NH C OtBu
t BuO
O
O
C NH
C Ot Bu
CH3
B1734
D2361
O t
D1899
O
O
BuO C NH P OCH2CH3
H2N P OCH2CH3 OCH2CH3
OCH2CH3
H0093
CH3
H0258
D1672
N H
OCH3
M1182
O
S O N C
CH3
O
N3
H0196
OCH2CH3 CH3
CH3
H0530
M0343 M0886 O
H2N OH
N
. HCl
H2N OH
N
2
. H2SO4
H2N O S OH
CH3ONH2
. HCl
O
P1235
P0403
D2479 O
O
T1184 O
NK
N
CH3
H C
N
O
O
P O
N N
CH3
O
. HCl
N H
NNa H C
O
Si
CH2N3
CH3
O
Product No. Product No. A1441 A1632 A1137 A1341 B2303 B1648 B2857 I0510 C1757 I0497 B1734 D2361 D1899 D1672 M1182 H0093 H0258 H0196 H0530 M0343 M0886 P1235 P0403 D2479 T1184
CH3
Acetoxime O-(2,4,6-Trimethylphenylsulfonate) N-Allyloxycarbonyl-2-nitrobenzenesulfonamide 4-Amino-1,2,4-triazole Azidomethyl Phenyl Sulfide N-(tert-Butoxycarbonyl)-2-nitrobenzenesulfonamide N-(tert-Butoxycarbonyl)-p-toluenesulfonamide tert-Butyl [Bis(4-methoxyphenyl)phosphinyloxy]carbamate tert-Butyl Methyl Iminodicarboxylate N-Carbobenzoxy-2-nitrobenzenesulfonamide Di-tert-butyl Iminodicarboxylate Diethyl N-(tert-Butoxycarbonyl)phosphoramidate Diethyl Phosphoramidate N,O-Dimethylhydroxylamine Hydrochloride Diphenylphosphoryl Azide Ethyl O-Mesitylsulfonylacetohydroxamate Hexamethylenetetramine Hydroxylamine Hydrochloride Hydroxylamine Sulfate Hydroxylamine-O-sulfonic Acid O-Methylhydroxylamine Hydrochloride O-Methylhydroxylamine Hydrochloride (ca. 40% in Water, ca. 5.4mol/L) Phthalimide DBU Salt Phthalimide Potassium Salt Sodium Diformylamide Trimethylsilylmethyl Azide
Unit Size 5g 25g 1g
5g 10g 1g 5g 5g
5g 1g
25g 25g 5g 25g 25g 25g 25g 25g 25ml 25g 1g
25g 5g 250g 5g 25g 25g 5g 5g 25g 25g 5g 25g 500g 250g 25g 500g 500g 500g 500g 500g 500ml 25g 500g 25g 5g
References 1) S. Gabriel, . 1887, , 2224; M. S. Gibson, R. W. Bradshaw, . 1968, , 919; U. Ragnarsson, L. Grehn, . 1991, , 285. 2) J. D. Elliott, J. H. Jones, . 1977, ; C. T. Clarke, J. D. Elliott, J. H. Jones, 1978, 1088; J. M. Chong, S. B. Park, . 1993, , 7300. 1999, 1301. 3) T. Fukuyama, M. Cheung, T. Kan, 2002, 4) T. Kan, A. Fujiwara, H. Kobayashi, T. Fukuyama, , 6267. 5) E. Erdik, M. Ay, . 1989, , 663. This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
125
Wittig & Horner-Emmons Reaction
Wittig & Horner-Emmons Reaction Wittig and Horner-Emmons reactions are useful reactions which react with aldehydes and ketones to form carbon-carbon double bonds and are frequently utilized in organic syntheses.1) Recently, syntheses of α,β-unsaturated esters have increasingly been performed using Wittig and Horner-Emmons reagents. In Horner-Emmons reactions, carbon-carbon double bonds generally lead to the -form. Attempts to selectively obtain -form are being investigated and reaction solvents, temperatures, and new Horner-Emmons reagents are being examined.2, 3) R O P CH2CO2Et
O
, Triton®B
2
Ph
CHO
Ph
THF, -78 °C
CO2Et
When R=Me Y. 100 % (Z : E = 96 : 4)
Ando has developed ethyl (diaryl)phosphonoacetate and found a method for the synthesis of selective -α,β-unsaturated ester.4) This method has received much attention as it utilizes quaternary ammonium hydroxide. The reaction is stable toward water and does not require special reactive technique. The reaction has an exceedingly high selectivity for -α,β-unsaturated ester.
A1305
A1439
A1007
O
O P CH2
Wittig Reaction
A1012
C CH3
P CH
Br
Cl
A0862
P CH2CH CH2
B2025
P
(CH2)4CH3
Cl
B0824
P CH2
B1206
P CH2
P CH2Br
Br
P CH2Cl
Cl
Br Cl
Br
B1208
P CH2CH CH2
C CH3
B0970
C1061
C1759
C1009 Cl
O P CH2CH2CH2Br
P
(CH2)3CH3
(CH2)4 C OH
P
CH2
Br
Br
Br
C1286
P
Cl
C1739
C1378
D2907
D1654 Cl
P CH2CH
CH
P
CH2CN
Cl
P
Br
P CH2
Cl
P CH2CH2N
Br
Cl
126
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Br
CH3 CH3
Wittig & Horner-Emmons Reaction
D1655
D2056
D2164
E0421
O
O P CH2CH2
P CH2CH2
O
O P CH2
O
O
E0407
Br
O
P CH2
Br
Br
Br
E0382
E0549
T1944
C1641
P+ CH2CH3 I -
Br
P
Br
F0331
O
O
P CH2CH3
P CH2 C OCH2CH3
OCH2CH3
O
P C C OCH2CH3
CH C OCH2CH3
P CH2
C H
CH3
H0545
H0540
H1240
Cl
I0552
M1326
HO O P
(CH2)6CH3 Br
P
(CH2)5CH3 Br
P CH(CH3)2 I
P CH2
P CH2
C OCH3 Br
Br
M0828
M0779
M0253
T1363
N0700
O P CH2OCH3
P CH3
P CH3
Br
I
P CH
C OCH3
P CH2
Cl
Cl
N0701
P1182
T2718
O CH2
P
NO2
P CH2
T1458
O
C
O
T1510
(CH2)3CH3 CH2 P
(CH2)3CH3
CH3
CH3
Br
P CH2CH2 Si CH3
P CH2OCH2CH2 Si CH3
(CH2)3CH3
CH3
Br
CH3
Cl
Br
T1498
T2001
I
T1958
T2002
T2565
O
CH3 P CH2C C Si CH3
P CH
O
C H
P
CHCN
P CH
C
P C C O
CH3 Br
P1438
P1200
P
CH2C
CH Br
T1506
P CH2CH2CH3 Br
Product No. Product Name A1305 A1439 A1007 A1012 A0862 B2025
Acetonyltriphenylphosphonium Chloride (Acetylmethylene)triphenylphosphorane Allyltriphenylphosphonium Bromide Allyltriphenylphosphonium Chloride Amyltriphenylphosphonium Bromide Benzyltriphenylphosphonium Bromide
T1644
P
(CH2)13CH3
Br
P CH CH2 Br
Unit Size
25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 25g 25g 25g 25g 250g
127
Wittig & Horner-Emmons Reaction
Product No. Product Name B0824 B1206 B1208 B0970 C1061 C1759 C1009 C1286 C1739 C1378 D2907 D1654 D1655 D2056 D2164 E0421 E0407 E0382 E0549 T1944 C1641 F0331 H0545 H0540 H1240 I0552 M1326 M0828 M0779 M0253 T1363 N0700 N0701 P1182 T2718 T1458 T1510 T1498 T2001 T1958 T2002 T2565 P1438 P1200 T1506 T1644
Unit Size
Benzyltriphenylphosphonium Chloride (Bromomethyl)triphenylphosphonium Bromide 3-Bromopropyltriphenylphosphonium Bromide Butyltriphenylphosphonium Bromide 4-(Carboxybutyl)triphenylphosphonium Bromide (2-Chlorobenzyl)triphenylphosphonium Chloride (Chloromethyl)triphenylphosphonium Chloride Cinnamyltriphenylphosphonium Bromide (Cyanomethyl)triphenylphosphonium Chloride Cyclopropyltriphenylphosphonium Bromide (2,4-Dichlorobenzyl)triphenylphosphonium Chloride 2-Dimethylaminoethyltriphenylphosphonium Bromide 2-(1,3-Dioxan-2-yl)ethyltriphenylphosphonium Bromide 2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium Bromide (1,3-Dioxolan-2-yl)methyltriphenylphosphonium Bromide 4-Ethoxybenzyltriphenylphosphonium Bromide Ethoxycarbonylmethyl(triphenyl)phosphonium Bromide Ethyltriphenylphosphonium Bromide Ethyltriphenylphosphonium Iodide Ethyl (Triphenylphosphoranylidene)acetate Ethyl 2-(Triphenylphosphoranylidene)propionate (Formylmethyl)triphenylphosphonium Chloride Heptyltriphenylphosphonium Bromide Hexyltriphenylphosphonium Bromide (2-Hydroxybenzyl)triphenylphosphonium Bromide Isopropyltriphenylphosphonium Iodide Methoxycarbonylmethyl(triphenyl)phosphonium Bromide (Methoxymethyl)triphenylphosphonium Chloride Methyltriphenylphosphonium Bromide Methyltriphenylphosphonium Iodide Methyl (Triphenylphosphoranylidene)acetate (1-Naphthylmethyl)triphenylphosphonium Chloride (4-Nitrobenzyl)triphenylphosphonium Bromide Phenacyltriphenylphosphonium Bromide Tributyl(1,3-dioxolan-2-ylmethyl)phosphonium Bromide 2-(Trimethylsilyl)ethoxymethyltriphenylphosphonium Chloride (2-Trimethylsilylethyl)triphenylphosphonium Iodide (3-Trimethylsilyl-2-propynyl)triphenylphosphonium Bromide (Triphenylphosphoranylidene)acetaldehyde (Triphenylphosphoranylidene)acetonitrile 2-(Triphenylphosphoranylidene)acetophenone (Triphenylphosphoranylidene)ketene Triphenylpropargylphosphonium Bromide Triphenylpropylphosphonium Bromide Triphenyl(tetradecyl)phosphonium Bromide Triphenylvinylphosphonium Bromide
B2815
25g 5g 10g 25g 5g
5g 5g 5g 5g 5g 25g 25g 25g 25g
25g 25g 5g 5g 25g 25g 25g 5g
5g 1g 5g 1g 5g 25g
B2801
B1714 O CH2 P
CH3O
Horner‒Emmons Reaction
CH3O
B2814
O CH3CH2O
128
O CH2
P OCH2CH3 OCH2CH3
CH3CH2O CH3CH2O
O CF3CH2O P CH2
O
CH3CH2O P CH2
OCH2CH3
P CH2 C OCH2
CH2 P
B1923
OCH2CH3
O
O
OCH2CH3
O
CH3
P CH2 C O C CH3 CH3
CF3CH2O
OCH2CH3
D3069
O
500g 25g 25g 25g 250g 25g 25g 25g 25g 5g 25g 25g 25g 25g 25g 25g 250g 500g 250g 250g 5g 25g 500g 500g 25g 25g 25g 500g 500g 500g 25g 25g 25g 25g 5g 25g 5g 5g 5g 25g 5g 5g 25g 500g 25g 5g
B1795
O CH2 CHCH2 P
O
OCH2CH3 OCH2CH3
CH3CH2O P CH2 CH3CH2O
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
O C OCH3
Wittig & Horner-Emmons Reaction
D3688
B1781 O
CH2 P
C1595
D3335
D3323 O
OCH2CH3
OCH2CH3
CH2 P
Cl
O
OCH2CH3
O
CH3CH2O P CH2CH2Br
CH2
CH3CH2O
OCH2CH3
O
OCH2CH3
P
NC
CH2 P
OCH2CH3
Br
OCH2CH3 OCH2CH3
Cl
C1430
D2423
E0483
D3324
D3689 O
O
O
CH3CH2O P CH2CN
OCH2CH3
O
CH3CH2O P CH2CH3
CH3CH2O P CH2 OCH2CH3
CH3CH2O
CH3CH2O
CH2 P
O F
CH2 P
CH3CH2O
OCH2CH3 OCH2CH3
OCH2CH3 OCH2CH3
I
D3325
D3326
D3708 O
CH3 CH3
O CH
CH2 P
D3327 O
OCH2CH3
CH2 P
O
O
OCH2CH3
OCH2CH3
D3873
CH3
OCH2CH3
P
N
OCH2CH3
O
OCH2CH3
CH3OCH2 P OCH2CH3
CH2 P
OCH2CH3
OCH2CH3 CH3
OCH2CH3
OCH3 OCH3
D3328
D3336 O
CH2 P
D3827 O
OCH2CH3
M1208
CH2 P
O
OCH2CH3
OCH2CH3
P1193
P
O
C CH2 P
CH3CH2O P CH2SCH3
OCH2CH3
OCH2CH3 OCH2CH3
CH3CH2O
P1258
D3992
M0943
O
O
O
OCH2CH3
CH3
D3174
CH3 C CH2
O
O CH3
CH3
D3339
OCH2CH3
O
P OCH2CH3
N CH2
OCH2CH3
O0208
P
S OCH2CH3 OCH2CH3
O
O C CH3
D2548
M1210
D2547 O
O CH3
CH P O 2
CH3O
CH3O
D3709
Cl
O
CH3O P CH3
OCH3
D3824
CH P O
O
O P OCH3
OCH2CH3
Cl Br
S
CH2 P OCH2CH3
O
D3875
CH3O P CH2
O
N
2
D2873
O
O
P O
N
C OCH2CH3
2
OCH3
D2445
O
O P CH2 2
T1582 O
O
O CH3 O O P CH2
O
CH3OCH2 P
O
O
CH3CH2O P CH2
C OCH2CH3
CH2
P CH3
C OCH3 O
CH3CH2O
2
P OCH2CH3 OCH2CH3
CH2
P OCH2CH3 OCH2CH3
M1319
(CH3)2CHO (CH3)2CHO
F0340
O
O
P CH2 P
OCH(CH3)2 OCH(CH3)2
CH3CH2O CH3CH2O
D1523 O
O
P
O
OCH2CH3 F
T2135
CH3CH2O P CH2 CH3CH2O
O C OCH2CH3
CH3CH2O CH3CH2O
D1524
O CH3 O
O
P CH C OCH2CH3 CH3CH2O P
O (CH2)2
C OCH2CH3
CH3CH2O
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
129
Wittig & Horner-Emmons Reaction
P1265
O
O
CH3O P CH2
C OCH3
CH3O
Product No. Product Name B2815 B2801 B1714 B1923 B2814 D3069 B1795 D3688 B1781 C1595 D3335 D3323 C1430 D2423 E0483 D3324 D3689 D3325 D3326 D3708 D3873 D3327 D3328 D3336 D3827 M1208 D3339 D3174 P1193 P1258 D3992 M0943 O0208 D3875 D3824 D3709 D2547 D2548 M1210 D2873 D2445 T1582 M1319 F0340 D1523 T2135 D1524 P1265
Benzyl Dimethylphosphonoacetate 9,10-Bis(diethylphosphonomethyl)anthracene Bis(2,2,2-trifluoroethyl) (Methoxycarbonylmethyl)phosphonate 4,4'-Bis(diethylphosphonomethyl)biphenyl tert-Butyl Diethylphosphonoacetate Diethyl Allylphosphonate Diethyl Benzylphosphonate Diethyl (4-Bromobenzyl)phosphonate Diethyl 2-Bromoethylphosphonate Diethyl (3-Chlorobenzyl)phosphonate Diethyl (4-Chlorobenzyl)phosphonate Diethyl (4-Cyanobenzyl)phosphonate Diethyl Cyanomethylphosphonate Diethyl 2,2-Diethoxyethylphosphonate Diethyl Ethylphosphonate Diethyl (4-Fluorobenzyl)phosphonate Diethyl (4-Iodobenzyl)phosphonate Diethyl (4-Isopropylbenzyl)phosphonate Diethyl (3-Methoxybenzyl)phosphonate Diethyl (N-Methoxy-N-methylcarbamoylmethyl)phosphonate Diethyl (Methoxymethyl)phosphonate Diethyl (2-Methylbenzyl)phosphonate Diethyl (3-Methylbenzyl)phosphonate Diethyl (4-Methylbenzyl)phosphonate Diethyl Methylphosphonate Diethyl (Methylthiomethyl)phosphonate Diethyl (2-Oxo-2-phenylethyl)phosphonate Diethyl (2-Oxopropyl)phosphonate Diethyl (Phthalimidomethyl)phosphonate Diethyl 1-Pyrrolidinemethylphosphonate Dimethyl 1,3-Benzodithiol-2-ylphosphonate Dimethyl Methylphosphonate Dimethyl (2-Oxopropyl)phosphonate Diphenyl 4-Bromo-α-chlorobenzylphosphonate Diphenyl α-Chlorobenzylphosphonate Diphenyl (N-Methoxy-N-methylcarbamoylmethyl)phosphonate Ethyl Diphenylphosphonoacetate Ethyl Di-o-tolylphosphonoacetate Methoxymethyl(diphenyl)phosphine Oxide Methyl Diethylphosphonoacetate Methyl(diphenyl)phosphine Oxide Tetraethyl p-Xylylenediphosphonate Tetraisopropyl Methylenediphosphonate Triethyl 2-Fluoro-2-phosphonoacetate Triethyl Phosphonoacetate Triethyl 2-Phosphonopropionate Triethyl 3-Phosphonopropionate Trimethyl Phosphonoacetate
Unit Size 1g
5g 1g 1g 5g 5g 1g 5g 5g 5g 5g 5g 5g 5g 1g 5g 5g 5g 5g 5g 5g 5g 5g
25g 5g 5g 1g 1g
5g 5g 5g
25g 1g 25g 25g 25g
1g 1g 25g 5g 1g 5g 25g 25g 25g 5g 25g 25g 25g 25g 25g 25g 25g 5g 25g 5g 25g 25g 25g 25g 25g 25g 1g 25g 25g 5g 1g 500g 25g 25g 5g 5g 1g 1g 25g 25g 10g 100g 25g 5g 500g 25g 250g 250g
References 1) H.-J. Altenbach, . 1979, , 940; R. D. Little, G. W. Muller, 1982, 391. Schmidt, N. H. Chishti, T. Breining, 2) S. K. Tompson, C. H. Heathcock, . 1990, , 3386; A. Redjal, J. Seyden-Penne, 1733. 3) W. C. Still, C. Gennari, . 1983, , 4405. 4) K. Ando, . 1995, , 4105; K. Ando, . 1997, , 1934; K. Ando, 2000, , 869; K. Ando, T. Oishi, M. Hirama, H. Ohno, T. Ibuka, Tokyo Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 10 265486, 1998.
130
. 1981,
, 2744; C. . 1974,
. 2000,
, 4745;
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Titanium-mediated Carbonyl Olefination
Titanium-mediated Carbonyl Olefination Carbonyl olefination is one of the most fundamental conversions in organic synthesis and a variety of synthetic methods have been developed and used. Especially, phosphorus mediated reactions such as Wittig and Horner-Emmons reactions have been widely investigated and several improved synthetic conditions, easy work up procedures and stereoselective Wittig type olefinations have been reported. Among these studies, a number of useful Wittig type reagents were provided and widely used for this transformation. In the 1990s, organotitanium species-promoted carbonyl olefination had been studied and various successful methods were reported.1) The biggest advantage of the use of organotitanium species in carbonyl olefination is that not only aldehydes and ketones, but also esters and lactones can be transformed to the corresponding olefins. Furthermore, the basicities of the organotitanium species are weaker compared to that of Wittig type bases and these chemical properties enable easily enolizable substrates to be used in carbonyl olefination and to produce the desired olefins with high yields.
Titanium-mediated carbonyl olefination
Ester, Lactone, Thiolester, Amide Wittig reaction Horner-Emmons reaction Aldehyde, Ketone
Tebbe2) and Petasis3) reagents are representative organotitanium reagents in carbonyl olefination which have been used for methylenation of various carbonyl compounds. Especially, Petasis reagent is a useful methylenating reagent because it is chemically stable to moisture and air in comparison to the Tebbe reagent.
Ti
Cl
Al
CH3 CH3
or
CH3 Ti CH3
O R1
(Tebbe Reagent)
CH2
(Petasis Reagent)
R1
Y
Y
Y = H, R2, OR2, SR2, NR2R3
Y = H, R2, OR2, SR2, NR2R3
On the other hand, olefination utilizing the RCHX2-TiCl4-Zn system reported by Takai and Utimoto enables alkylidenation of carbonyl groups. In this reaction, the stereochemistry of the double bond is preferentially.4) R
O R1
Y
RCHX2-TiCl4-Zn-TMEDA
Y = H, R2, OR2, SR2, NR2R3
R1
Y
Y = H, R2, OR2, SR2, NR2R3
Takeda reported more general alkylidenation of carbonyl compounds by the treatment of thioacetals with a titanocene(II) compound.5) Even though the titanocene(II) compound needs to be prepared before use, thioacetals can be easily synthesized from aldehydes and thiophenol. Therefore, this synthetic procedure can be applied to wide range of alkylidenation of carbonyl compounds. Takeda also reported the synthesis of tetrasubstituted olefins by the alkylidenation of carbonyl compounds with an organotitanium species prepared from a titanocene(II) compound and -dihalides.6)
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
131
Titanium-mediated Carbonyl Olefination
O R2 SPh R1
2Cp2Ti[P(OEt)3]2
R
SPh
1
Y R2
R1
TiCp2
Y Cp2Ti=O
Y = H, R3, OR3, SR3
Preparation of low valent titanium species
Cl Ti Cl
= Cp2TiCl2
Mg, 2P(OEt)3
Cp2Ti[P(OEt)3]2 Low valent titanium species
Preparation of thioacetals SPh
2PhSH, BF3 EOEt
O R1
R1
H
BuLi, R1X
H H
SPh
PhS
SPh
Thioacetal
O X X R1
R2
R3
R2
Y
R2
2Cp2Ti[P(OEt)3]2 R1
R3
R1 Y
TiCp2
X = Cl, Br
Y = H, R4, OR4, SR4
Cp2Ti=O
There are several types of organotitanium species-promoted carbonyl olefination and some active intermediates have been proposed. In one of them, it is considered that methylenation performed by Tebbe and Petasis reagents proceeds via a Schrock type titanium-methylidene complex as an active intermediate. Therefore, dependent on structures of substrates and reaction conditions, when the substrate possesses a carbonyl function and a carbon-carbon double bond in the same molecule, olefination and a subsequent ring-closing metathesis (RCM) occurs in one-pot. This sequential process has been applied to the total synthesis of marine natural products having a cyclic polyether structure.7)
Ti CH2 O O O
R
R 6 or 7 menberd cyclic products
Tebbe or Petasis reagent-promoted olefination with a subsequent RCM proceeds only when the substrate is fixed by a cyclic structure, and cyclization of this is limited within 6- and 7-membered cyclic systems.7) On the other hand, olefination-subsequent RCM of acyclic substrates can be performed by the use of the CH3CHBr2-TiCl4-Zn system.8) TiCl4, Zn, TMEDA
O
O
PbCl2, CH3CHBr2
O
6 or 7 menberd cyclic products
It is known that the reactivity of CH3CHBr2-TiCl4-Zn system is higher than that of Tebbe and Petasis reagents. So olefination-subsequent RCM successfully proceeds even when acyclic substrates, the structure-flexibility of which is higher compared to that of cyclic substrates, are employed. Furthermore, CH3CHBr2-TiCl4-Zn system-promoted RCM of dienes has been reported, which was synthetically difficult when using other organotitanium reagents.8) TiCl4, Zn, TMEDA R1 O R2
n
PbCl2, CH3CHBr2
R1 R2 O
n = 0, 1, 2 n
Although organotitanium species-promoted olefination-subsequent RCM is dependent on the structure of the substrate, it is synthetically very available for use in the RCM process. TCI deals in various organotitanium reagents such as Tebbe and Petasis reagents and titanocene dichloride, which is used for preparation of organotitanium species. 132
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Titanium-mediated Carbonyl Olefination
D3956
C1411
CH3
Organotitanium Reagents
Ti
CH3
T2052
Ti
Cl
Al
CH3
TiCl4
CH3
T0616
Cl
Ti
Cl
Product No. Product Name D3956 C1411 T2052 T0616
Unit Size
Dimethyltitanocene (=Petasis Reagent) (5% in Toluene) Tebbe Reagent (ca. 0.5mol/L in Toluene) Titanium(IV) Chloride (14% in Dichloromethane, ca. 1.0mol/L) Titanocene Dichloride
B0041
100g 25ml 100ml 25g
5g
B1444
B0527
SH SCH2S
Others
B0396
D0184
D0192
D1106
D0610
CH3
Br
Cl
N
CH3
CH3 H3C
Cl Cl
CH3 N
CH3
CH3
O CH3
O
Product No. Product Name B0041 B1444 B0527 B0396 D0184 D0192 D1106 D0400 D0610 T0147 T0430
O
T0430 CH3
CH3
CH3
D0400
CH3CH2 C CH3
CH2Br2
T0147
CH2I2
.
Cl
Br Li
CH3
BF3
Benzenethiol Bis(phenylthio)methane Boron Trifluoride - Ethyl Ether Complex Butyllithium (ca. 15% in Hexane, ca. 1.6mol/L) 1,1-Dibromoethane (stabilized with Copper chip) Dibromomethane 2,2-Dichlorobutane 2,2-Dichloropropane Diiodomethane (stabilized with Copper chip) N,N,N ',N '-Tetramethylethylenediamine Triethyl Phosphite
P
O
CH3
Unit Size 25ml 5g 25ml 100ml 25g
25g 25ml 25ml
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500ml 25g 500ml 500ml 5g 500g 10ml 10ml 500g 500ml 500ml
133
Titanium-mediated Carbonyl Olefination
References 1) 2) 3) 4) 5) 6) 7) 8)
134
, ed. by T. Takeda, Wiley-VCH, 2004. F. N. Tebbe, G. W. Parshall, G. S. Reddy, . 1978, , 3611. N. A. Petasis, E. I. Bzowej, . 1990, , 6392. T. Okazoe, K. Takai, K. Oshima, K. Utimoto, . 1987, , 4410. Y. Horikawa, M. Watanabe, T. Fujiwara, T. Takeda, . 1997, , 1127. T. Takeda, R. Sasaki, T. Fujiwara, . 1998, , 7286. K. C. Nicolaou, M. H. D. Postema, C. F. Claiborne, . 1996, , 1565. K. Iyer, J. D. Rainier, . 2007, , 12604.
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Suzuki-Miyaura Cross-Coupling Reaction
Suzuki-Miyaura Cross-Coupling Reaction The Suzuki-Miyaura reaction is a palladium catalyzed cross-coupling reaction between organic boron compounds and organic halides.1) The reaction requires an additional base for the activation of the boron compound and proceeds under mild conditions. This relatively simple and versatile C-C bond formation reaction can be extended to various substrates and therefore finds wide application for the synthesis of pharmaceuticals and total synthesis of complex natural products. R1 BXn +
PdLn
R2 Y
R1 R 2
Base
Xn = (OH)2, (OR)2, R2, F3K
Y = Cl, Br, I, OTf etc.
Ln = Ligand
The usefulness of this reaction has been well documented by the synthesis of biaryl compounds in 1981,3) triggered by the initial synthesis of dienes using the vinyl-type boron compounds initiated in 1979.2) Eventually the reaction also proved applicable to the coupling reaction of alkyl halides and alkylboranes. Organotrifluoroborates also represent an effective alternative to boronic acids and boronate esters being stable towards numerous reagents and allow the manipulation of functional groups within them.4) -Heterocyclic carbenes prepared from imidazolium and imidazolinium salts can also be efficiently employed as ligands in addition to organophosphine compounds.5) Recently, the synthesis of biaryl compounds without the aid of ligands has also been accomplished.6) It has been recently reported that nickel can also catalyze the above reaction with the same efficiency as the expensive palladium catalysts specially in case of difficult substrates like aryl chlorides in which reaction does not proceed easily with conventional palladium as the catalyst. In addition to being inexpensive, nickel catalysts can also be removed much easily from the reaction system.7) Proper choice of metals, ligands, bases and solvents enable the widespread application of the SuzukiMiyaura cross-coupling reaction to various substrates and different synthetic sequences. We provide a wide range of organic boron compounds as coupling partners. In this section, we introduce different varieties of reaction partners in addition to the organoboron compounds, such as metal catalysts and phosphine ligands to explore the versatile applicability of the Suzuki-Miyaura cross-coupling reaction.
A1479
B2029
CH2 HC
Palladium Catalysts
Pd Cl
CH2
P
CH2
Cl Pd
B1676
3
CH CH2
Pd
Cl
(CH3CN)2PdCl2
CH2
P 3
B1668
B3224
CN Pd
B1374 Ph Ph P
Cl
Pd
Cl Ph
Cl Cl
CH CH C CH CH
Fe
B2192
P C(CH ) 3 3 C(CH3)3
B2161
Ph P Ph PdCl2. CH2Cl2 P Ph
Ph Ph P Cl Pd Cl P
Ph
Ph
Ph
Ph Ph P Cl Pd P Cl Ph Ph
PdCl2
Fe
Pd
2
B2064 Ph Ph P Pd P Ph Ph
C(CH3)3 P C(CH3)3 2
Ph
B2031
O
P
CN
B2016
B3160
B2018 CH3
CH3Ph2P Pd CH3Ph2P
O
Cl
Pd
Cl
O CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
2
135
Suzuki-Miyaura Cross-Coupling Reaction
B3161
B2055
B2042
B1667
B2026 CH3
[(CH3)3C]3P [(CH3)3C]3P
P 3
Pd
Cl
3
Pd Cl
P
O
P
O C CH3
Pd
3
P
Cl
Pd
O C CH3
P
3
P 3
CH3
Cl
Cl
Pd
Cl
P
O
3
P
3
3
C2387
C2372 i-Pr
i-Pr
C2406 i-Pr N
N
i-Pr
i-Pr
i-Pr
i-Pr
HN
i-Pr CH3O
Pd Cl
O
CH3O
N CH3 CH3
CH3
P1491 P1785 P1490
CH3O
i-Pr N
N
i-Pr
i-Pr
Pd Pd Cl
Pd Cl N CH3 CH3
P1489
A1424
HN
Cl Cl
O CH3
P1528
P1870
O
O
Pd
N i-Pr
D2604 i-Pr
i-Pr N
N
Pd Cl
C2407 i-Pr
i-Pr
N
CH3 C O
PdCl2
Pd2
Pd(OH)2
CF3
2
P1425
S0540
T1350
O
Pd2 2
T2184 O
CH3
CH3
P
NH
PdCl2
Na2PdCl4
P 3
20
Pd 4
B2192 B2161 B2018 B3161 B2055 B2042 B1667 B2026 C2387 C2372 C2406
C2407 D2604 P1491 P1785 P1490
136
Ph Ph
Pd
Pd O
Ph Ph
2
n
Product No. Product Name A1479 B2029 B1676 B1668 B3224 B1374 B3160 B2031 B2016 B2064
Ph
Ph
O
Allylpalladium(II) Chloride Dimer Benzylbis(triphenylphosphine)palladium(II) Chloride Bis(acetonitrile)palladium(II) Dichloride Bis(benzonitrile)palladium(II) Dichloride Bis[1,2-bis(diphenylphosphino)ethane]palladium(0) Bis(dibenzylideneacetone)palladium(0) [1,1'-Bis(di-tert-butylphosphino)ferrocene]palladium(II) Dichloride [1,4-Bis(diphenylphosphino)butane]palladium(II) Dichloride [1,2-Bis(diphenylphosphino)ethane]palladium(II) Dichloride [1,1'-Bis(diphenylphosphino)ferrocene]palladium(II) Dichloride Dichloromethane Adduct [1,3-Bis(diphenylphosphino)propane]palladium(II) Dichloride Bis(methyldiphenylphosphine)palladium(II) Dichloride Bis(2,4-pentanedionato)palladium(II) Bis(tri-tert-butylphosphine)palladium(0) Bis(tricyclohexylphosphine)palladium(II) Dichloride Bis(triphenylphosphine)palladium(II) Diacetate Bis(triphenylphosphine)palladium(II) Dichloride Bis(tri-o-tolylphosphine)palladium(II) Dichloride Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](acetanilide)palladium(II)] (This product is unavailable for selling domestically in U.S.) Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](N,N-dimethylbenzylamine)palladium(II)] (This product is unavailable for selling domestically in U.S.) Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](N,N-dimethyl3,5-dimethoxybenzylamine)palladium(II)] (This product is unavailable for selling domestically in U.S.) Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](4'-methoxyacetanilide)palladium(II)] (This product is unavailable for selling domestically in U.S.) Dichloro(1,5-cyclooctadiene)palladium(II) Palladium 10% on Carbon (wetted with ca. 55% Water) Palladium 10% on Carbon (wetted with ca. 55% Water) [Useful catalyst for coupling reaction, etc.] Palladium 5% on Carbon (wetted with ca. 55% Water)
O
Unit Size 500mg 100mg 1g 1g 1g 1g 1g 1g 1g
1g 1g 5g 5g 5g 5g 5g 5g 5g
5g 1g 1g 1g 250mg 1g 1g 1g 5g
25g 5g 5g 5g 1g 5g 5g 25g 1g
200mg
1g
200mg
1g
200mg
1g
200mg 1g 5g 5g 5g
1g 5g 25g 25g 25g
1g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Suzuki-Miyaura Cross-Coupling Reaction
Product No. Product Name A1424 P1430
Unit Size
Palladium(II) Acetate Palladium Catalyst Set (includes useful 7 Palladium catalysts)
1g
5g
1g 10g 1g
1set 5g 50g 5g
Palladium(II) Acetate Allylpalladium(II) Chloride Dimer Bis(benzonitrile)palladium(II) Dichloride Bis(dibenzylideneacetone)palladium(0) [1,1'-Bis(diphenylphosphino)ferrocene]palladium(II) Dichloride Dichloromethane Adduct Bis(triphenylphosphine)palladium(II) Dichloride Tetrakis(triphenylphosphine)palladium(0)
P1489 P1528 P1870 P1425
Palladium(II) Chloride Palladium Hydroxide 20% on Carbon (wetted with ca. 50% Water) Palladium(II) Trifluoroacetate Poly[N-isopropylacrylamide-co-4-(diphenylphosphino)styrene] Palladium(II) Dichloride
S0540 T1350 T2184
Sodium Tetrachloropalladate(II) Tetrakis(triphenylphosphine)palladium(0) Tris(dibenzylideneacetone)dipalladium(0)
100mg
(ratio, acrylamide:phosphine=20:2)
1g
B2225
B2226 Ph
Nickel Catalysts
B3534
Ph
P
O 3
O CH3
Ph
Ph
Ph
3
Cl
Ni
Cl
P Ph
Cl
P
3
3
Unit Size
[1,2-Bis(diphenylphosphino)ethane]nickel(II) Dichloride [1,1'-Bis(diphenylphosphino)ferrocene]nickel(II) Dichloride [1,3-Bis(diphenylphosphino)propane]nickel(II) Dichloride Bis(2,4-pentanedionato)nickel(II) Hydrate Bis(tricyclohexylphosphine)nickel(II) Dichloride Bis(triphenylphosphine)nickel(II) Dichloride Skeletal Nickel Catalyst slurry in Water [Active catalyst for Hydrogenation]
B2711
1g
Fe P
C(CH3)3 C(CH3)3 C(CH3)3 C(CH3)3
5g 1g 5g 25g 10g
B2710
P
Phosphine Ligands
Cl Ni
Cl
Product No. Product Name B2225 B2226 B1313 N0096 B3534 B1571 S0487
Ph P
P
Cl Ni
P 2
Ph P Ph NiCl2 P Ph
B1571
CH3 Ni
Fe
Cl
P Ph
N0096
Cl
Ni
5g 1g
B1313
Ph P
1g 1g 25g 5g
25g 5g 25g 500g 1g 100g 50g
B1406
P Fe P
CH(CH3)2 CH(CH3)2 CH(CH3)2
PPh2 PPh2
CH(CH3)2
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
137
Suzuki-Miyaura Cross-Coupling Reaction
B1405
B1246
B2709
B1137 CH3
CH3
PPh2
PPh2
P (CH2)4
PPh2
P
P CH2CH2 P
O P
B1113
P
CH3 O CH3 O H
B2867 (C6H5)2P
B1982
CH2 P
CH3 O
CH2
P
CH2 P
CH3 O
CH2
P
B1138
PPh2
2
B1112 H
(CH2)6 P
P
P
D3387
(CH2)5 P
D2411
(CH3)3C
C(CH3)3 P CH2CH2CH2
B1960
P CH2
D3940
P(C6H5)2 O
Fe
P
2
B1959
B2027
C(CH3)3 P
P
P
P C(CH3)3
D3388
D3389
D2535
D2536
D2775 CH3
CH3 P N(CH3)2 PPh2
2
P
(CH3)2N Ph2P
Fe
OCH3 P(C6H5)2
Fe
(CH3)2N
D2766
E0519
T0361
T1912
T1165
t Bu
Bu CH2
P
Bu
P CH2CH3
P
t
P
Bu
t Bu
Bu
T1643
T0519
P
P
T1614
T0861
T1024 OCH3
CH3O
O O
P
P
O
CH3O
3
CH3O
T1025
OCH3
CH3
T0862 CH3
CH3
CH3
CH3
CH3
P
P
P
P P CH3
CH3
CH3
Product No. Product Name B2711 B2710 B1406 B1405 B1246 B2709
138
1,1'-Bis(di-tert-butylphosphino)ferrocene 1,1'-Bis(diisopropylphosphino)ferrocene (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl 1,4-Bis(diphenylphosphino)butane 4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene
Unit Size 100mg 100mg 1g 1g 5g 1g
1g 1g 5g 5g 25g 5g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Suzuki-Miyaura Cross-Coupling Reaction
Product No. Product Name
Unit Size
B1137 B2027 B1959 B1113 B1112 B1982 B1960 B2867 B1138 D3940 D3387 D2411 D3388 D3389 D2535 D2536 D2775 D2766
1,2-Bis(diphenylphosphino)ethane 1,1'-Bis(diphenylphosphino)ferrocene 1,6-Bis(diphenylphosphino)hexane (2R,3R)-(-)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol (2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol Bis(diphenylphosphino)methane 1,5-Bis(diphenylphosphino)pentane Bis[2-(diphenylphosphino)phenyl] Ether 1,3-Bis(diphenylphosphino)propane Di-tert-butylphenylphosphine 2-(Di-tert-butylphosphino)biphenyl Dicyclohexylphenylphosphine 2-(Dicyclohexylphosphino)biphenyl 2-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenyl (R)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine (S)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine (S)-(-)-2-Diphenylphosphino-2'-methoxy-1,1'-binaphthyl 4-Diphenylphosphinomethyl Polystyrene Resin cross-linked with 2% DVB (200-400mesh)
E0519 T0361 T1912 T1165
Ethyldiphenylphosphine Tributylphosphine Tri-tert-butylphosphine Tricyclohexylphosphine (contains Tricyclohexylphosphine Oxide)
T1643 T0519 T1614 T0861 T1024 T1025 T0862
Tri(2-furyl)phosphine Triphenylphosphine Tris(2,6-dimethoxyphenyl)phosphine Tris(4-methoxyphenyl)phosphine Tris(2-methylphenyl)phosphine Tris(3-methylphenyl)phosphine Tris(4-methylphenyl)phosphine
10g 5g 1g
1g
5g
5g
1g 1g 1g
100mg
(0.5-1.0mmol/g)
25ml 25ml 1g 25g
(ca. 18% in Toluene, ca. 0.60mol/L)
5g 5g 5g 5g
B3506
-Heterocyclic Carbene Ligands
B3465
B3158
(CH3)2CH
N
N
CH3 CH CH3
N
CH3 CH CH3
CH3 CH3 CH3 CH CH3
N
CH
CH3
N (CH3)2CH
N CH(CH3)2 CH(CH3)2
CH(CH3)2
N Cl
(CH3)2CH
CH(CH3)2
Cl
D3882
CH3 N
CH3 CH3
C CH3
N
CH3
N
BF4
(CH3)3C
N
N
C(CH3)3
N
Cl
CH3 C CH3
Cl
CH3
CH3
D3446
500ml 5g 500g 25g 25g 25g 25g 25g
(CH3)2CH
D3472
CH3
N N
CH3 CH3 CH3 CH CH3 CH
N
5g 5g 500ml 5g
D3611
CH3 CH CH3
D3711 CH3
CH3 CH CH3
B3157
25g 25g 5g 1g 1g 25g 1g 5g 25g 5g 1g 5g 5g 5g 100mg 100mg 1g
D3870 CH3
CH3
N N CH3
CH3
CH3
CH3 CH3
N
N
Cl CH3
CH3 CH3
CH3
CH3
Product No. Product Name B3506 B3157 D3611 B3465 B3158 D3711
1,3-Bis(2,6-diisopropylphenyl)imidazolidin-2-ylidene 1,3-Bis(2,6-diisopropylphenyl)imidazolinium Chloride 1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride 1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene 1,3-Bis(2,4,6-trimethylphenyl)imidazolinium Chloride 1,3-Di-tert-butylimidazolium Tetrafluoroborate
Unit Size 500mg 500mg 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
1g 5g 5g 5g 5g 5g
139
Suzuki-Miyaura Cross-Coupling Reaction
Product No. Product Name D3472 D3882 D3446 D3870
Unit Size
1,3-Di-tert-butylimidazol-2-ylidene 1,3-Dicyclohexylimidazolium Chloride (This product is only available for selling domestically in Japan) 1,3-Dimesitylimidazolium Chloride 1,3-Dimesitylimidazol-2-ylidene
H1176
T1848
1g 1g 1g 1g
5g 5g 5g 5g
T0508 O
CH3 C O
O CF3(CF2)7 S
Others
F
O
Sb
As
CH3 C O O
Product No. Product Name H1176 T1848 T0508
Unit Size
Heptadecafluoro-1-octanesulfonyl Fluoride Triphenylantimony Diacetate Triphenylarsine
25g
250g 1g 5g
Bases & Additives Product No. Product Name D0905 B2695 B0468 B1018 B0709 C2430 C2160 C2204 D0925 D1599 L0204 L0222 M0508 P0221 P0081 P1748 P1758 P1779 S0560 S0485 T0054 T0057 Z0015
Bathophenanthroline Bathophenanthroline (refined product of D0905) 2,2'-Bipyridyl 1,8-Bis(dimethylamino)naphthalene [for Dehydrohalogenation] tert-Butylamine Cesium Acetate Cesium Carbonate Cesium Fluoride Diisopropylamine N,N-Diisopropylethylamine Lithium Chloride Anhydrous Lithium Chloride (2.3% in Tetrahydrofuran, ca. 0.5mol/L) 1-Methylimidazole 1,10-Phenanthroline Monohydrate 1,10-Phenanthroline Hydrochloride Monohydrate Potassium Carbonate Potassium Fluoride Potassium Fluoride Anhydrous (Spray-dried) Sodium Carbonate Sodium Methoxide Tetrabutylammonium Bromide Tetrabutylammonium Iodide Zinc (Powder)
Unit Size 1g
1g
25ml
25g 5g 25ml 25g 25g 25g 25ml 100ml 25g 25g 1g
100g 25g 25g
5g 1g 500g 25g 500ml 100g 100g 100g 500ml 500ml 300g 100ml 500g 25g 25g 300g 300g 25g 300g 500g 500g 500g 300g
References 1) Review: A. Suzuki, . 2005, 4759; A. Suzuki, 2005, 2004, , 312; A. Suzuki, , 359; N. Miyaura, A. Suzuki, . 1995, , 2457. 2) N. Miyaura, K. Yamada, A. Suzuki, . 1979, , 3437. 3) T. Yanagi, N. Miyaura, A. Suzuki, . 1981, , 513. 4) Review: G. A. Molander, N. Ellis, . 2007, , 275. 5) Review: E. A. B. Kantchev, C. J. O'Brien, M. G. Organ, . 2007, , 2768. 6) T. Maegawa, Y. Kitamura, S. Sako, T. Udzu, A. Sakurai, A. Tanaka, Y. Kobayashi, K. Endo, U. Bora, T. Kurita, A. Kozaki, Y. Monguchi, H. Sajiki, . 2007, , 5937. 2006, 7) Review: T. Kamikawa, , 53.
140
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Iron-Catalyzed Organic Synthesis
Iron-Catalyzed Organic Synthesis Including palladium catalysts, which are frequently used for the Suzuki-Miyaura coupling reaction, transition metal catalysts, such as nickel, copper, or rhodium, have been widely used for organic synthesis. However, the percentages of these metals in the earth’s crust are extremely small, and their prices are rather expensive.1) On the other hand, iron is abundant and less expensive, therefore, more and more chemists have focused their attention to organic synthesis using iron compounds as a catalyst. 2) For instance, with regards to the reactions of Grignard reagents with alkyl bromides, Hayashi and 3) Chai have reported the synthetic methods using Fe(acac)3 as a catalyst, Fe(OAc)2 as a catalyst and Xantphos as a ligand, respectively, by which the desired coupling products can be obtained in good yields. Fe(acac)3 (5 mol%)
(CH2)5CH3
MgBr
+
Et2O, reflux, 0.5 h
Br
(CH2)5CH3 Y. 73%
Br 8
Fe(OAc)2 (3 mol%)
O PPh2
PPh2
Xantphos (6 mol%)
MgBr
+
8
Et2O, rt, 15 min
Y. 64%
Furthermore, Nakamura have reported the method using the -heterocyclic carbene generated from SIPr・HCl, which suppresses the generation of the homo-coupling products, thereby leading to an excellent yield of the desired product.4) Cl
iPr
N iPr
FeF3 3H2O (5 mol%) Cl
+ BrMg
iPr
N + iPr
SIPr HCl (15 mol%)
THF, 60 °, 24 h Y. 98%
Thus, synthetic technologies using iron catalysts are being actively developed. It can be expected that iron catalysts will exhibit their own catalytic properties in addition to replacing other metal catalysts in the near future.
D2571
I0765
T1686 Ph
N
N
O
O Fe2
Fe
Iron Catalysts
O
CH3
O
O
Fe O
2
Ph
H0555
I0079
T0750 CH3
CF3 O
CF3 O
O Fe
Fe
Fe
O CF3
O
O 3
3
CH3
3
CH3
3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
141
Iron-Catalyzed Organic Synthesis
Product No. Product Name
Unit Size
N,N '-Bis(salicylidene)ethylenediamine Iron(II) Iron(II) Acetate Tris(dibenzoylmethanato) Iron Tris(hexafluoroacetylacetonato)iron(III) Tris(2,4-pentanedionato)iron(III) Tris(trifluoro-2,4-pentanedionato)iron(III)
D2571 I0765 T1686 H0555 I0079 T0750
5g 5g 5g
25g 25g 25g 1g 500g 5g
25g
B3372
B2709 CH3
CH3
PPh2 PPh2
O
Phosphine Ligands
Ligands
B1137
B1982
P
D3387
P CH2
D2471
(CH3)3C
P
P 2
2
T1912
C(CH3)3 t Bu
P P
P CH2CH2 P
t
Bu
P
N
T1165
t Bu
T0519
P
P
Product No. Product Name B3372 B2709 B1137 B1982 D3387 D2471 T1912 T1165 T0519
Unit Size
1,2-Bis(diphenylphosphino)benzene 4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene 1,2-Bis(diphenylphosphino)ethane Bis(diphenylphosphino)methane 2-(Di-tert-butylphosphino)biphenyl Diphenyl-2-pyridylphosphine Tri-tert-butylphosphine Tricyclohexylphosphine (contains Tricyclohexylphosphine Oxide) (ca. 18% in Toluene, ca. 0.60mol/L) Triphenylphosphine
D0905
D0720
CH3
Bidentate Nitrogen Ligands
N
142
N H
H N
25ml 25g
T0147 CH3
N CH3
N
5g 5g 25g 25g 1g 1g 5g 500ml 500g
. H2O
CH3
N
N
CH3
CH3
N
Product No. Product Name D0905 D0720 P0879 T0147
P0879
1g 1g 10g 5g
Bathophenanthroline N,N '-Dimethylethylenediamine 1,10-Phenanthroline Monohydrate N,N,N ',N '-Tetramethylethylenediamine
Unit Size 1g 5ml 25ml
5g 25ml 25g 500ml
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Iron-Catalyzed Organic Synthesis
B3506
B3157 CH3 CH CH3
NHC & Precursors
CH3 CH CH3
B3158
CH3 CH3 CH3
D3621
(CH3)2CH
CH(CH3)2
D3711
N
N
N
CH3 CH3 CH3
CH CH
CH3
C CH3 CH3
N
BF4
Cl
BF4
BF4
(CH3)3C
N
N
C(CH3)3
CH3 C CH3 CH3
CH3
D3882
D3850
D3622
N
D3623
N
N Cl
D3870
CH
D3446
CH3 N
CH3
CH
CH3
CH3
CH3
N
CH3
CH3
N
N
N
BF4
CH
CH3 CH3
BF4
N CH
CH3
BF4
CH3
CH3
CH3
Cl
CH3
P1816 CH3
CH3 N CH3
CH3 CH CH3
D3472
N
N
CH3
N
Cl
N
CH3
CH3
CH3
Cl
CH3
N N
CH(CH3)2
N CH(CH3)2
N
CH3
D3620 CH3
CH(CH3)2
N (CH3)2CH
CH3 CH CH3
N
N
CH CH
B3465
(CH3)2CH
(CH3)2CH
N N
D3611
N
N
CH3 CH3
CH3
N
N CH3
N N
2Br
CH3
Product No. Product Name B3506 B3157 D3611 B3465 B3158 D3620 D3621 D3711 D3472 D3882 D3850 D3622 D3623 D3446 D3870 P1816
1,3-Bis(2,6-diisopropylphenyl)imidazolidin-2-ylidene 1,3-Bis(2,6-diisopropylphenyl)imidazolinium Chloride 1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride 1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene 1,3-Bis(2,4,6-trimethylphenyl)imidazolinium Chloride 1,3-Di(1-adamantyl)imidazolinium Tetrafluoroborate 1,3-Di(1-adamantyl)imidazolium Tetrafluoroborate 1,3-Di-tert-butylimidazolium Tetrafluoroborate 1,3-Di-tert-butylimidazol-2-ylidene 1,3-Dicyclohexylimidazolium Chloride (This product is only available for selling domestically in Japan) 1,3-Dicyclohexylimidazolium Tetrafluoroborate 1,3-Diisopropylimidazolinium Tetrafluoroborate 1,3-Diisopropylimidazolium Tetrafluoroborate 1,3-Dimesitylimidazolium Chloride 1,3-Dimesitylimidazol-2-ylidene 1,1'-(2,6-Pyridinediyl)bis(3-methylimidazolium) Dibromide
Unit Size 500mg 500mg 1g 1g
1g 1g 1g 1g 1g 1g
1g 5g 5g 5g 5g 500mg 1g 5g 5g 5g 5g 5g 1g 5g 5g 1g
References 1) 2) 3) 4)
J. Emsley, in , 3rd ed., Oxford Univ. Press, New York, 1998. 2004, , 1297. T. Nagano, T. Hayashi, 2007, K. G. Dongo, H. Koh, M. Sau, C. L. L. Chai, , 1015. 2007, T. Hatakeyama, M. Nakamura, , 9844.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
143
Metal Catalysts
Metal Catalysts for Organic Synthesis
T1548
T1550
T1304
O
O CF3
Homogeneous Catalysts
A0804
OCH(CH3)2
Al
Al
OC(CH3)3
(CH3)2CHO
CF3
O
M1211
2
A0241 tBu
t
CH3 Bu
O
Cl CH3CH2 Al
OCH(CH3)2
CH3
Cl
Mg2
S O
O
E0648
OC(CH3)3
O
S ONa
O
A0246
(CH3)3CO
CF3
S OLi
O
Al
CH3
O
Al
O
CH3 tBu
tBu
CH3
A1267
T1549
T1663
B1588
3
C1994
CF3 O
O Al
CF3
O CH3
O
S OK
CF3
O
O Sc3
S O O
Ti O
Cl
O
3
Ti
Cl
Cl
3
D2257
I0646
P1651
B0742
T0967
CH3 Cl
CH3
(CH3)2CHO Ti OCH(CH3)2 Cl
Cl
Ti
CH3(CH2)3O Ti
Cl
CH3 Ti CH3 Cl3
Cl
T0978
T0133
T0666
OCH2CH3
O(CH2)3CH3
CH3
O(CH2)3CH3
CH3CH2O Ti OCH2CH3
O(CH2)3CH3
C0336
OCH2CH3
H0557 CF3
CH3 OCH(CH3)2
OCH2CH(CH3)2 (CH3)2CHCH2O Ti OCH2CH(CH3)2
(CH3)2CHO Ti OCH(CH3)2
OCH2CH(CH3)2
O(CH2)17CH3 CH3(CH2)17O Ti O(CH2)17CH3
M0042 O N
N
CH3
T0685
Mn
T1686
CH3
2
N
CF3
CH3
Fe
Fe CH3
CH3
CH3 CH3
O
CH3
N
3
CH3
N
CH3
O
Co
O
O 3
2
O
O
O
O
B2314 CF3
Fe
O
Fe2 O
2
CH3
Fe
O CH3
T0750
O
O
N Fe
O
I0079 CF3
3
2
I0765
Mn O
H0555 Ph
144
. 2H2O
O CH3
Ph
D2571
O
O
Mn O O Ph Ph
CF3
3
CF3
CH3
C O
. xH2O
O
O CH3
B2409
Mn
Cr
O(CH2)17CH3
OCH(CH3)2
O
O
3
CH3
O CH3
CH3
O CH3
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Metal Catalysts
B2315
H0553
CH3
CH3
CH3 CH3
B1844
CF3
CH3
O
N
CH3
N
O
Co CH3
. xH2O
Co
O
O
CH3
O
CH3
CH3
B2681
CF3
O
O
Co CH3
Ph
OC
Fe
Ph
CO
Ph
Ph
Ph
Ni Cl
P
CH3
Cl
O
Cl
O
2
H0554
O
N
N
Cl
N
CF3
Ni N
Br
CH3
CF3
Br
CH3
(CH3)2CH
CH3
N
N N
2
T1292 CH3
CH(CH3)2 Cu Cl CH(CH3)2
. xH2O
Cu O
2
C2422
Cu O
O Ni2
S O O
N
O
CH3
CH3
2
CF3
2
. xH2O
Ni O
N0861
(CH3)2CH
CH3
O
Ni . xH2O
CF3
Ph
3
N0096
CF3
Ph
C2304
O
O
CF3 Cl
Ni
Cu
O
CH3
P
T0752
O
O Co
O
Ni
3
CH3
N Co
CO
P
P
3
C0384
CH3
P 3
2
C0374
N
B3354
Cl
3
CH3
H0558
Ph P Ph NiCl2 P Ph
B1571
P
O
O CH3
CO Co
. 2H2O
Co
O
CH3
B1313
Cl
B3534
O
CO
Co
2
Ph
P
O
CH3
S0318
OC
B2226
Cl
O
Co
CH3
CH3
OC
. xH2O
O
Ni
O
CH3
CH3 N
CO
O
P
CH3
D3213
Co
Ph
Co
CH3
Ph
N
CH3
O
B2225
CH3 Ph CH3
N
CF3
2
CH3
CH3 N
2
O
CH3
C0373
Ph
CH3
O
T0746 CH3
CH3 Ph
O CH3
B1845
O
CH3 Cu Cl CH3
N CH3
CF3
Cu2
S O O
2
2
CH3
T1442
D2542
O CF3
Cu2
S O O
.
2
C1995
Z0002
H3C CH3 N Cu N H3C CH3
H3C CH3 N Cu O N H H3C CH3
Zn
CH3
B1902
Cl
Ru Cl
Ru Cl
O Zr
O
B3067
Cl
CH3 O
CH3
4
CF3SO3
Zr SO3CF3
.
Mo O
O
CH3
4
B3068
C2201
Ph
Ph
P
P
Ph Cl Ru Cl P Ph Ph
3
M0464
CF3
O
Y3
S O O
2
2
Zr
Cl
CF3
Z0009
O Cl
Zn2
S O O
T0747 CH3
Zr
CF3
O CH3
O
O
O 2Cl
Z0006
Cl
T1921
CH3
2
H O
T1294
Ph Cl Ru Cl P Ph Ph
O O
2
D2751 (CH3)2CH
CH3 Cl
Ph3P Ru PPh3 Cl
Cl Ru
Ru Cl Cl
CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
CH(CH3)2
145
Metal Catalysts
H1010
P1688
R0074
R0086
T1559
(C6H11)3P Cl Cl
Ru
Pr
Cl
Cl
Ru
Cl
Ru Cl
RuCl3
. H2O
RuCl3NO
Pr
N Pr
(C6H11)3P
T1655
RuO4
Pr
T2183
D1997
B2090
B2091
2
CH3
N N
O
N
P
Ru
2Cl
Ru N
N N
B1692
Cl Cl
3
BF4 Rh
(CH3)3C
3
C2253
2
P
Rh
C(CH3)3
CH3
C1383
BF4
CH3
P
CH3
. 6H2O
Rh
3
O
B1045
N0453
P 3
Cl
CO
Rh
P
CO
Rh
H
Cl
Cl
Rh
Rh
Cl
Cl
Rh
Cl
P
Rh
Rh
Rh Cl
3 3
P1788
R0069
T2054
T2055
CH3 O Cl Cl
Rh Cl
Rh
Cl
CH3
R
H
O
CH3 O O Rh
Rh O O
O
Rh
Rh
O O O
R
O
OO
R O
O H
R
. 2 CH3
H OO
R
O
Rh Rh O O O H R
O
R=
H
O
Cl Cl Cl
. 2 CH3
Rh
N
O O
O
Cl
C OCH2CH3
T1544
R R'
Ph O Rh O O Ph Ph Ph
Rh
Rh
O
O
O
N
R=
O
H
O
. 2 CH3
R
R
O
O
Cl Cl
O H
C OCH2CH3
Cl
N
R=
O
. 2 CH3
O
Cl
C OCH2CH3
T2661
H R' OO
O
R
H R'
R
R O
Rh
O O O
R'=
O O O
R
O
R
O
O
O
. 2 CH3
O
F
H OO
Rh Rh
N
R=
F
H
R
F F
O
H
O
. CH3
OO
Rh Rh
CH2
H
H
O
N
R=
R
H
O
O
H
O O O
R
H
R
C OCH2CH3
H OO
Rh Rh
O
H
O
R
R
O O O
R H
R
C OCH2CH3
R
O
R=
N
O
F F F
O H
. 2 CH3
O
O
F
C OCH2CH3
C OCH2CH3
T0931 Ph Ph O
OO
O O O
R
H
H
O
T2660 R' H
R O
A1479
B2029
B1676
Ph Ph Ph O O Ph Rh
O
CH2
P 3
O Ph Ph
. CH2Cl2
B1668
Rh
Cl
Pd
3
Ph Ph P
Cl
Pd
Cl
3
CH CH2
Pd
Cl
(CH3CN)2PdCl2
CH2
P
B3160 C(CH3)3 P C(CH3)3
CH CH C CH CH 2
Ph
Cl Fe
B2031
O
P Ph
Cl
Pd Cl
B1374
B2192
P C(CH ) 3 3 C(CH3)3
B2161
Ph P Ph PdCl2. CH2Cl2 P Ph
Ph Ph P Cl Pd Cl P
Ph
Ph
Ph
Ph Ph P Cl Pd P Cl Ph Ph
PdCl2
Fe
Pd
2
B2064 Ph Ph P Pd P Ph Ph
P
CH2
Cl Pd
3
CN
B2016
HC CH2
B3224
CN
146
N
R=
T1551 H
R
O
O
H
R
H
H
O
CH3
T2659
T2658
R
B2018 CH3
CH3Ph2P Pd CH3Ph2P
O
Cl
Pd
Cl
O CH3
2
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Metal Catalysts
B3292
B3161
B2055
B2042
O
O S
O C CH3
O
O
B3553
P 3
Pd
N
N N
Cl
Pd Br
i-Pr N
O C
Cl HN
C2407
D3806 i-Pr
i-Pr
i-Pr
i-Pr
N
N OH
Pd Cl O
Cl
CH3
i-Pr
N CH3 CH3
D3807
D2604 OH CH3
HO Pd N OH
CH3
Cl Pd Cl
N
Cl
Pd
Cl
HO
Cl
A1424
i-Pr
Pd Cl
CH3O
N CH3 CH3
CH3 CH3 N Cl Pd Pd Cl N CH3 CH3
HO Cl Pd Pd Cl
N
i-Pr CH3O
Pd Cl
O
i-Pr N
N
i-Pr
D3847 Cl
N
i-Pr
i-Pr N
Cl
i-Pr N
HN
C2406 i-Pr
CH3
3
Cl
P
O
Pd Cl
P
Cl
Pd
3
N
i-Pr
N
P 3
O C CH3
P
C2372 i-Pr
O C
Pd
O C CH3
3
C2387
CH3
P1489
P1870
S0540
T1350
O
O
PdCl2
Pd2
CH3 C O
C2373
Na2PdCl4
Pd2
O
CF3
2
T2184
P
Pd
3
2
T1331
D2466
4
T1194
(CH3)2CH
O Ph
Ph Ph Ph
Cl
3
B2026
CH3
3
Pd P
O
P
Cl
3
Pd
[(CH3)3C]3P
O C CH3
S
P
[(CH3)3C]3P
Pd
CH3O
B1667
Pd
Pd O
Ph Ph
CH(CH3)2 Ag Cl CH(CH3)2
(CH3)2CH
(CH2)3CH3
O
N N
CF3
CF3SO3
S OAg
Sn
SO3CF3
O CF3
(CH2)3CH3
O
Sn2
S O O
2
O
T1918
T1293
T1919
T1920
L0148 CH3
O CF3
O Ce3
S O O
CF3
T1610
La3
S O O
3
O
O CF3
Nd3
S O O
3
T1708
CF3
O Tm3
S O O
3
C1807
La
. xH2O
O
3
CH3
P1763
3
B3115 CH3
O CF3
O Yb3
S O O
3
. xH2O
B3162
[(CH3)3C]3P [(CH3)3C]3P
CF3
Hf4
S O O
Cl
Ir
Cl
Cl
Ir
Ir
Cl
O
Cl
Pt O
4
D3592
Pt
Ir
Cl
CH3
2
T2485
Pt
Cl Cl
P 3
Pt 4
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
147
Metal Catalysts
Product No. Product Name T1548 T1550 T1304 A0804 A0246 E0648 M1211 A0241 A1267 T1549 T1663 B1588 C1994 D2257 I0646 P1651 B0742 T0967 T0978 T0133 T0666 C0336 H0557 B2409 M0042 T0685 D2571 I0765 T1686 H0555 I0079 T0750 B2314 B2315 H0553 B1844 B1845 C0373 B2681 T0746 D3213 S0318 C0374 B2225 B2226 B1313 H0558 N0096 B3534 B1571 B3354 N0861 H0554 C0384 T0752 C2304 C2422 T1292 T1442 D2542 Z0002 T1294 T1921 C1995
148
Lithium Trifluoromethanesulfonate Sodium Trifluoromethanesulfonate Magnesium Trifluoromethanesulfonate Aluminum tert-Butoxide Aluminum Isopropoxide Ethylaluminum Dichloride (17% in Hexane, ca. 1mol/L) Methylaluminum Bis(2,6-di-tert-butyl-4-methylphenoxide) (0.4mol/L in Toluene) Tris(2,4-pentanedionato)aluminum(III) Tris(trifluoro-2,4-pentanedionato)aluminum(III) Potassium Trifluoromethanesulfonate Scandium(III) Trifluoromethanesulfonate [1,2-Benzenediolato(2-)-O,O ']oxotitanium Cyclopentadienyltitanium(IV) Trichloride Dichlorotitanium Diisopropoxide (Indenyl)titanium(IV) Trichloride (Pentamethylcyclopentadienyl)titanium(IV) Trichloride Tetrabutyl Orthotitanate Tetraethyl Orthotitanate Tetraisobutyl Orthotitanate (contains Isopropoxide) Tetraisopropyl Orthotitanate Tetraoctadecyl Orthotitanate Tris(2,4-pentanedionato)chromium(III) Bis(hexafluoroacetylacetonato)manganese(II) Hydrate (1S,2S)-N,N '-Bis[(R)-2-hydroxy-2'-phenyl-1,1'-binaphthyl-3-ylmethylene]-1,2-diphenylethylenediaminato Manganese(III) Acetate Bis(2,4-pentanedionato)manganese(II) Dihydrate Bis(trifluoro-2,4-pentanedionato)manganese(II) N,N '-Bis(salicylidene)ethylenediamine Iron(II) Iron(II) Acetate Tris(dibenzoylmethanato) Iron Tris(hexafluoroacetylacetonato)iron(III) Tris(2,4-pentanedionato)iron(III) Tris(trifluoro-2,4-pentanedionato)iron(III) (1R,2R)-N,N '-Bis(2-acetyl-3-oxo-2-butenylidene)-1,2-dimesitylethylenediaminato Cobalt(II) (1S,2S)-N,N '-Bis(2-acetyl-3-oxo-2-butenylidene)-1,2-dimesitylethylenediaminato Cobalt(II) Bis(hexafluoroacetylacetonato)cobalt(II) Hydrate (1R,2R)-N,N '-Bis[3-oxo-2-(2,4,6-trimethylbenzoyl)butylidene]-1,2-diphenylethylenediaminato Cobalt(II) (1S,2S)-N,N '-Bis[3-oxo-2-(2,4,6-trimethylbenzoyl)butylidene]-1,2-diphenylethylenediaminato Cobalt(II) Bis(2,4-pentanedionato)cobalt(II) Dihydrate Bis(2,4-pentanedionato)cobalt(II) Bis(trifluoro-2,4-pentanedionato)cobalt(II) Hydrate Dicobalt Octacarbonyl (stabilized with 1-5% Hexane) Salcomine [=N,N '-Bis(salicylidene)ethylenediiminocobalt(II)] Tris(2,4-pentanedionato)cobalt(III) [1,2-Bis(diphenylphosphino)ethane]nickel(II) Dichloride [1,1'-Bis(diphenylphosphino)ferrocene]nickel(II) Dichloride [1,3-Bis(diphenylphosphino)propane]nickel(II) Dichloride Bis(hexafluoroacetylacetonato)nickel(II) Hydrate Bis(2,4-pentanedionato)nickel(II) Hydrate Bis(tricyclohexylphosphine)nickel(II) Dichloride Bis(triphenylphosphine)nickel(II) Dichloride Bromo[(2,6-pyridinediyl)bis(3-methyl-1-imidazolyl-2-ylidene)]nickel Bromide Nickel(II) Trifluoromethanesulfonate Bis(hexafluoroacetylacetonato)copper(II) Hydrate Bis(2,4-pentanedionato)copper(II) Bis(trifluoro-2,4-pentanedionato)copper(II) Chloro[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper(I) Chloro(1,3-dimesitylimidazol-2-ylidene)copper(I) Copper(II) Trifluoromethanesulfonate Copper(I) Trifluoromethanesulfonate Benzene Complex Di-μ-hydroxo-bis[(N,N,N ',N '-tetramethylethylenediamine)copper(II)] Chloride Bis(2,4-pentanedionato)zinc(II) Zinc(II) Trifluoromethanesulfonate Yttrium(III) Trifluoromethanesulfonate Cyclopentadienylzirconium(IV) Trichloride
Unit Size 5g 5g 100g
25g 5g 1g 1g 5g
25g 25ml 25g 25g 25g 1g
25g 5g 5g 5g 25g
25g 25g 25g 25g 500g 100ml 50ml 500g 25g 25g 5g 1g 5g 25g 1g 1g 500g 500ml 25ml 500g 500g 500g 5g 100mg 500g 5g 25g 25g 25g 1g 500g 5g 100mg 100mg 5g 100mg
25g
25g 1g
100g 25g 5g 1g 5g 1g 25g 10g 1g 1g 25g 200mg 200mg 5g 1g 5g 25g 5g 1g
100mg 500g 25g 5g 5g 500g 500g 25g 5g 25g 5g 500g 1g 100g 1g 5g 5g 250g 5g 1g 1g 25g 5g 25g 500g 25g 25g 5g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Metal Catalysts
Product No. Product Name Z0006 T0747 Z0009 M0464 B1902 B3067 B3068 C2201 D2751 H1010 P1688
Tetrakis(2,4-pentanedionato)zirconium(IV) Tetrakis(trifluoro-2,4-pentanedionato)zirconium(IV) Zirconocene Bis(trifluoromethanesulfonate) Tetrahydrofuran Adduct Bis(2,4-pentanedionato)molybdenum(VI) Dioxide Benzeneruthenium(II) Chloride Dimer [(R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II) Dichloride [(S)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II) Dichloride Cyclopentadienylbis(triphenylphosphine)ruthenium(II) Chloride Dichloro(p-cymene)ruthenium(II) Dimer (Hexamethylbenzene)ruthenium(II) Dichloride Dimer (3-Phenyl-1H-inden-1-ylidene)bis(tricyclohexylphosphine)ruthenium(IV) Dichloride
R0074 R0086 T1559 T1655 T2183 D1997 B2090
Ruthenium(III) Chloride Ruthenium(II) Nitrosyl Chloride Monohydrate Tetrapropylammonium Perruthenate Tris(2,2'-bipyridyl)ruthenium(II) Chloride Hexahydrate Tris(2,4-pentanedionato)ruthenium(III) Tris(triphenylphosphine)ruthenium(II) Dichloride (S,S)-1,2-Bis[(tert-butyl)methylphosphino]ethane[η-(2,5-norbornadiene)]rhodium(I) Tetrafluoroborate Bis[η-(2,5-norbornadiene)]rhodium(I) Tetrafluoroborate Carbonylbis(triphenylphosphine)rhodium(I) Chloride Carbonyltris(triphenylphosphine)rhodium(I) Hydride Chlorobis(cyclooctene)rhodium(I) Dimer Chloro(1,5-cyclooctadiene)rhodium(I) Dimer Norbornadiene Rhodium(I) Chloride Dimer (Pentamethylcyclopentadienyl)rhodium(III) Dichloride Dimer Rhodium(II) Acetate Dimer Tetrakis[N-phthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-phthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrachlorophthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrachlorophthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-phthaloyl-(S)-phenylalaninato]dirhodium Ethyl Acetate Adduct Tetrakis[N-tetrafluorophthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrafluorophthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis(triphenylacetato)dirhodium(II) Dichloromethane Adduct Tris(triphenylphosphine)rhodium(I) Chloride Allylpalladium(II) Chloride Dimer Benzylbis(triphenylphosphine)palladium(II) Chloride Bis(acetonitrile)palladium(II) Dichloride Bis(benzonitrile)palladium(II) Dichloride Bis[1,2-bis(diphenylphosphino)ethane]palladium(0) Bis(dibenzylideneacetone)palladium(0) [1,1'-Bis(di-tert-butylphosphino)ferrocene]palladium(II) Dichloride [1,4-Bis(diphenylphosphino)butane]palladium(II) Dichloride [1,2-Bis(diphenylphosphino)ethane]palladium(II) Dichloride [1,1'-Bis(diphenylphosphino)ferrocene]palladium(II) Dichloride Dichloromethane Adduct [1,3-Bis(diphenylphosphino)propane]palladium(II) Dichloride Bis(methyldiphenylphosphine)palladium(II) Dichloride Bis(2,4-pentanedionato)palladium(II) 1,2-Bis(phenylsulfinyl)ethane Palladium(II) Diacetate Bis(tri-tert-butylphosphine)palladium(0) Bis(tricyclohexylphosphine)palladium(II) Dichloride Bis(triphenylphosphine)palladium(II) Diacetate Bis(triphenylphosphine)palladium(II) Dichloride Bis(tri-o-tolylphosphine)palladium(II) Dichloride Bromo[[1,3-bis[(4S,5S)-1-benzoyl-4,5-diphenyl-2-imidazolin2-yl]benzene]palladium(II)] Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](acetanilide)palladium(II)] (This product is unavailable for selling domestically in U.S.) Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](N,N-dimethylbenzylamine)palladium(II)] (This product is unavailable for selling domestically in U.S.) Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](N,N-dimethyl3,5-dimethoxybenzylamine)palladium(II)] (This product is unavailable for selling domestically in U.S.) Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](4'-methoxyacetanilide)palladium(II)] (This product is unavailable for selling domestically in U.S.) Di-μ-chlorobis[5-chloro-2-[(4-chlorophenyl)(hydroxyimino)methyl]phenyl]palladium(II) Dimer
Unit Size 25g 1g 1g
1g 1g 100mg 1g
Tetrahydrofuran Adduct
B2091 B1692 C1383 C2253 B1045 N0453 P1788 R0069 T2054 T2055 T2658 T2659 T1551 T2660 T2661 T1544 T0931 A1479 B2029 B1676 B1668 B3224 B1374 B3160 B2031 B2016 B2064 B2192 B2161 B2018 B3292 B3161 B2055 B2042 B1667 B2026 B3553 C2387 C2372 C2406
C2407 D3806
1g 1g 1g 1g
100mg 1g 100mg 100mg
100mg
1g 500mg 100mg 1g 1g 1g 1g 1g 1g 1g 1g
5g 1g 1g 1g 200mg 250mg 1g 1g 1g 5g
500g 1g 5g 25g 5g 250mg 250mg 5g 5g 1g 1g 5g 1g 5g 5g 5g 5g 50mg 1g 1g 5g 500mg 1g 100mg 200mg 1g 100mg 100mg 50mg 100mg 100mg 50mg 100mg 100mg 5g 1g 1g 5g 5g 5g 5g 5g 5g 5g 25g 5g 5g 5g 1g 1g 5g 5g 25g 1g 100mg
200mg
1g
200mg
1g
200mg
1g
200mg
1g
250mg
1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
149
Metal Catalysts
Product No. Product Name D3847 D3807 D2604 A1424 P1430
Unit Size
Di-μ-chlorobis[2-[(dimethylamino)methyl]phenyl-C,N]dipalladium(II) Di-μ-chlorobis[5-hydroxy-2-[1-(hydroxyimino)ethyl]phenyl]palladium(II) Dimer Dichloro(1,5-cyclooctadiene)palladium(II) Palladium(II) Acetate Palladium Catalyst Set (includes useful 7 Palladium catalysts) Palladium(II) Acetate Allylpalladium(II) Chloride Dimer Bis(benzonitrile)palladium(II) Dichloride Bis(dibenzylideneacetone)palladium(0) [1,1'-Bis(diphenylphosphino)ferrocene]palladium(II) Dichloride Dichloromethane Adduct Bis(triphenylphosphine)palladium(II) Dichloride Tetrakis(triphenylphosphine)palladium(0)
P1489 P1870 S0540 T1350 T2184 C2373 T1331 D2466 T1194 T1918 T1293 T1919 T1920 L0148 T1610 T1708 C1807 P1763 B3115 B3162 D3592 T2485
Palladium(II) Chloride Palladium(II) Trifluoroacetate Sodium Tetrachloropalladate(II) Tetrakis(triphenylphosphine)palladium(0) Tris(dibenzylideneacetone)dipalladium(0) Chloro[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]silver Silver Trifluoromethanesulfonate Dibutyltin Bis(trifluoromethanesulfonate) Tin(II) Trifluoromethanesulfonate Cerium(III) Trifluoromethanesulfonate Lanthanum(III) Trifluoromethanesulfonate Neodymium(III) Trifluoromethanesulfonate Thulium(III) Trifluoromethanesulfonate Tris(2,4-pentanedionato)lanthanum(III) Hydrate Ytterbium(III) Trifluoromethanesulfonate Hydrate Hafnium(IV) Trifluoromethanesulfonate Chloro(1,5-cyclooctadiene)iridium(I) Dimer (Pentamethylcyclopentadienyl)iridium(III) Dichloride Dimer Bis(2,4-pentanedionato)platinum(II) Bis(tri-tert-butylphosphine)platinum(0) Dichloro(1,5-cyclooctadiene)platinum(II) Tetrakis(triphenylphosphine)platinum(0)
1g 1g 5g 5g
250mg 1g 1g
1g 1g 1g
5g 1g 200mg 10g
1g
5g 5g 5g
5g 1g
200mg
1set 5g 5g 1g 25g 5g 1g 25g 5g 25g 5g 25g 25g 5g 25g 25g 5g 1g 1g 1g 250mg 1g 1g
Heterogeneous Catalysts Product No. Product Name P1702 P1703 P1491 P1785 P1490 P1701 P1528 P1786 R0075 R0076 S0487
Palladium 5% on Barium Sulfate Palladium 5% on Calcium Carbonate (poisoned with Lead) Palladium 10% on Carbon (wetted with ca. 55% Water) Palladium 10% on Carbon (wetted with ca. 55% Water) [Useful catalyst for coupling reaction, etc.] Palladium 5% on Carbon (wetted with ca. 55% Water) Palladium 5% on Barium Carbonate Palladium Hydroxide 20% on Carbon (wetted with ca. 50% Water) Palladium on SH Silica Gel (0.1mmol/g) Rhodium 5% on Carbon (wetted with ca. 55% Water) Ruthenium 5% on Carbon (wetted with ca. 50% Water) Skeletal Nickel Catalyst slurry in Water [Active catalyst for Hydrogenation]
Unit Size 5g 5g 5g 5g 5g 10g
5g
25g 25g 25g 25g 25g 10g 50g 1g 1g 25g 50g
Polymer-Supported Reagents (see p.24) References 1) C. Elschenbroich, J. Oliveira, in , 3rd ed., Wiley-VCH, Weinheim, 2006. 2) Y. Murakami, J. Kikuchi, Y. Hisaeda, O. Hayashida, . 1996, , 721.
150
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Grignard Reagents & Alkyl Metals
Grignard Reagents & Alkyl Metals
A0963
A1554
B1883 CH2MgBr
CH2
MgBr
Grignard Reagents
B1933
B1884
CH2
B0726
C1504
B1147 B1148
CH2MgCl
C1505
MgBr
CH3
CH3 CH3
MgCl
CH3
MgBr
C2039
CH3
MgCl
MgCl CH3
D3551
E0135 E0778
E0134 E0497 MgBr
MgBr
MgBr
CH3
CH3
MgBr
CH3
MgCl
CH3
H0821
H0822
I0517
I0518
CH3
CH3
MgBr
CH3
MgBr
M0364
M0785 M0362
P0190
P1381
CH3
CH3
MgBr
P0191
T1700
CH3(CH2)14MgBr
P0880
MgCl
CH3
MgBr
T1698 MgBr
MgI
T1451
CH3
P1177
CH3
T1699
CH3
MgBr
P1251
MgCl
MgBr
CH3
MgBr CH3
O0240
CH3MgI
CH3MgBr
I0542 I0543
MgBr
CH3
V0053
MgBr
MgBr
CH3 CH3 CH3
Si
CH2MgCl
CH2 CHMgBr
CH3 CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
151
Grignard Reagents & Alkyl Metals
Product No. Product Name A0963 A1554 B1883 B1933 B1884 B0726 B1147 B1148 C1504 C1505 C2039 D3551 E0134 E0497 E0135 E0778 H0822 H0821 I0517 I0518 I0542 I0543 M0785 M0362 M0364 O0240 P1251 P1177 P0190 P1381 P0191 P0880 T1698 T1699 T1700 T1451 V0053
Unit Size
Allylmagnesium Bromide (ca. 13% in Ethyl Ether, ca. 0.7mol/L) Allylmagnesium Chloride (ca. 9% in Tetrahydrofuran, ca. 0.8mol/L) Benzylmagnesium Bromide (ca. 12% in Tetrahydrofuran, ca. 0.6mol/L) Benzylmagnesium Chloride (ca. 16% in Tetrahydrofuran, ca. 1mol/L) sec-Butylmagnesium Bromide (16% in Tetrahydrofuran, ca. 1mol/L) Butylmagnesium Chloride (23% in Tetrahydrofuran, ca. 2mol/L) tert-Butylmagnesium Chloride (26% in Ethyl Ether, ca. 2mol/L) tert-Butylmagnesium Chloride (23% in Tetrahydrofuran, ca. 2mol/L) Cyclohexylmagnesium Bromide (ca. 17% in Tetrahydrofuran, ca. 1mol/L) Cyclopentylmagnesium Bromide (18% in Tetrahydrofuran, ca. 1mol/L) Cyclopropylmagnesium Bromide (ca. 10% in Tetrahydrofuran, ca. 0.7mol/L) (2,5-Dimethylphenyl)magnesium Bromide (20% in Tetrahydrofuran, ca. 1mol/L) Ethylmagnesium Bromide (39% in Ethyl Ether, ca. 3mol/L) Ethylmagnesium Bromide (13% in Tetrahydrofuran, ca. 1mol/L) Ethylmagnesium Chloride (18% in Tetrahydrofuran, ca. 2mol/L) Ethylmagnesium Chloride (ca. 1.0mol/L in Tetrahydrofuran) activated with Zinc Chloride (ca. 10mol%) Heptylmagnesium Bromide (21% in Tetrahydrofuran, ca. 1mol/L) Hexylmagnesium Bromide (20% in Tetrahydrofuran, ca. 1mol/L) Isobutylmagnesium Bromide (17% in Tetrahydrofuran, ca. 1mol/L) Isopropylmagnesium Bromide (15% in Tetrahydrofuran, ca. 1mol/L) Isopropylmagnesium Chloride (13% in Ethyl Ether, ca. 1mol/L) Isopropylmagnesium Chloride (ca. 11% in Tetrahydrofuran, ca. 1mol/L) Methylmagnesium Bromide (35% in Ethyl Ether, ca. 3mol/L) Methylmagnesium Bromide (12% in Tetrahydrofuran, ca. 1mol/L) Methylmagnesium Iodide (33% in Ethyl Ether, ca. 2mol/L) n-Octylmagnesium Bromide (ca. 22% in Tetrahydrofuran, ca. 1mol/L) Pentadecylmagnesium Bromide (17% in Tetrahydrofuran, ca. 0.5mol/L) Pentylmagnesium Bromide (18% in Tetrahydrofuran, ca. 1mol/L) Phenylmagnesium Bromide (32% in Tetrahydrofuran, ca. 2mol/L) Phenylmagnesium Chloride (27% in Tetrahydrofuran, ca. 2mol/L) Phenylmagnesium Iodide (42% in Ethyl Ether, ca. 2mol/L) Propylmagnesium Bromide (ca. 27% in Tetrahydrofuran, ca. 2mol/L) o-Tolylmagnesium Bromide (19% in Tetrahydrofuran, ca. 1mol/L) m-Tolylmagnesium Bromide (19% in Tetrahydrofuran, ca. 1mol/L) p-Tolylmagnesium Bromide (19% in Tetrahydrofuran, ca. 1mol/L) Trimethylsilylmethylmagnesium Chloride (20% in Ethyl Ether, ca. 1mol/L) Vinylmagnesium Bromide (14% in Tetrahydrofuran, ca. 1mol/L)
A1479
A1222
CH2 HC
Alkyl Metals
B1975
B1832 (CH2)3CH3
CH3(CH2)3
Sn
CH3(CH2)3 Sn
(CH2)3CH3
(CH2)3CH3
CH3(CH2)3
D0305
152
Sn
(CH2)3CH3 CH
CH3(CH2)3
CH2
B0396
Sn
(CH2)3CH3
Sn CH2CH (CH2)3CH3
B2651
CH3
CH3 C Li
Li
CH3(CH2)3 (CH2)3CH3
CH3
Al Cl
CH3
CH3(CH2)3
D1338
Zn(CH2CH3)2
(CH2)3CH3
(CH2)3CH3 Cl
CH3
D3214 D3902
(CH2)3CH3
D0223
Sn Cl (CH2)3CH3
D1373
Cl CH3
CH3(CH2)3
CH2 CH3(CH2)3 Sn C C Sn (CH2)3CH3
CH3
CH3(CH2)3 (CH2)3CH3 CH3(CH2)3 Sn
D1340
O CH3
Pd Cl
CH2
B1974
CH2
Cl Pd
100ml 100g 100g 250g 100g 250g 250g 250g 100g 100g 100g 100g 250g 250g 250g 250g 250g 250g 250g 250g 250g 250g 250g 250g 100g 250g 250g 250g 250g 250g 250g 250g 100g 100g 100g 100ml 100g
CH3 Sn CH3 Cl
O CH3(CH2)7 Sn (CH2)7CH3
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Grignard Reagents & Alkyl Metals
H0842
M0589
M0258
M0744
T2009
CH2CH CH2
O CH3
T0058
T0919
(CH2)3CH3
Sn CH3
(CH2)3CH3 CH3(CH2)3 Sn H (CH2)3CH3
CH3
CH3
(CH2)3CH3
(CH2)3CH3
CH3
CH3
Si CH2 CH3
Sn
(CH2)3CH3
CH3 CH3
CH3
Cl
(CH2)3CH3 CH3(CH2)3 Sn F
(CH2)3CH3
(CH2)3CH3
T1086 T0783 T0925 (CH2)3CH3
CH3(CH2)3 Sn
(CH2)3CH3
Sn Cl CH3
CH3
CH CH2
Al
CH3
CH3
(CH2)3CH3
(CH2)7CH3 CH3(CH2)7 Sn
H
(CH2)7CH3
CH3
Product No. Product Name A1479 A1222 B1974 B1975 B1832 B0396 B2651 D0223 D0305 D1340 D3214 D3902 D1338 D1373 H0842 M0589 M0258 M0744 T2009 T0058 T0919 T1750 T0363 T0678 T1473 T1865 T1866 T1794 T1086 T0783 T0925 T1330 T0784
(CH2)3CH3
T1572
CH3 CH3
CH2CH CH2
T0678
CH3(CH2)3 Sn
(CH2)3CH3
T0958
Al
OH
T1794
CH3
(CH2)3CH3
Si C C Sn
CH3 Al
CH3
T1866
CH3 CH3
C CH
(CH2)3CH3
T0782 T1575
CH3
CH3(CH2)3 Sn
CH3
T1865
CH2 CHCH2 Sn CH2CH CH2
Sn
T0363
CH3 CH3
(CH2)3CH3
T1473
CH3
T1750
(CH2)3CH3 CH3(CH2)3 Sn (CH2)3CH3
T1330 T0784
CH3HgI
CH3HgCl
Li
Allylpalladium(II) Chloride Dimer Allyltributyltin Bis(tributylstannyl)acetylene trans-1,2-Bis(tributylstannyl)ethylene Bis(tributyltin) Butyllithium (ca. 15% in Hexane, ca. 1.6mol/L) tert-Butyllithium (ca. 16% in Pentane, ca. 1.6mol/L) Dibutyltin Dichloride Dibutyltin Oxide Diethylaluminum Chloride (ca. 15% in Hexane, ca. 0.87mol/L) Diethylzinc (ca. 17% in Hexane, ca. 1mol/L) Diethylzinc (ca. 15% in Toluene, ca. 1mol/L) Dimethyltin Dichloride Di-n-octyltin Oxide Hexyllithium (30% in Hexane, ca. 2.3mol/L) Methylmercuric Chloride Methylmercuric Iodide Monobutyltin Oxide Tetraallyltin Tetrabutyltin Tetramethyltin Tributylethynyltin Tributyltin Chloride Tributyltin Fluoride Tributyltin Hydride (stabilized with BHT) [Reducing Reagent] Tributyl(trimethylsilylethynyl)tin Tributyl(trimethylsilylmethyl)tin Tributylvinyltin Triethylaluminum (15% in Benzene, ca. 1.1mol/L) Triethylaluminum (15% in Hexane, ca. 1.0mol/L) Triethylaluminum (15% in Toluene, ca. 1.1mol/L) Triisobutylaluminum (15% in Heptane, ca. 0.53mol/L) Triisobutylaluminum (15% in Hexane, ca. 0.50mol/L)
Unit Size 500mg 5g 1g 1g 5g 100ml 25g 25g
25g 25g
25g 1g 25g 5g 1g 25g 25g 5g 1g
5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
1g 25g 5g 5g 25g 500ml 100ml 500g 500g 100ml 100ml 100ml 500g 500g 100ml 5g 25g 500g 5g 500g 25g 5g 500g 25g 250g 25g 5g 25g 100ml 100ml 100ml 100ml 100ml
153
Grignard Reagents & Alkyl Metals
Product No. Product Name T0782 T1575 T0958 T1572
Trimethylaluminum (15% in Hexane, ca. 1.4mol/L) Trimethylaluminum (15% in Toluene, ca. 1.8mol/L) Trimethyltin Chloride Tri-n-octyltin Hydride [Reducing Reagent]
Unit Size 5g
100ml 100ml 25g 10g
Many alkyl metals, Grignard reagents may spontaneously ignite on contact with air, or may react violently with water to produce flammable gas. Sufficient safety measures, such as usage of safety shield, wearing of protective equipment, and extreme caution should be taken, when using this compound, from the opening up to the disposal of the reagents.
154
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Protection & Derivatization
Protection & Derivatization In organic synthesis, appropriate use of protecting agents is very important to a synthetic strategy. Useful protecting agents must have the following properties: - the protecting agent must selectively react with the functional group that requires protection. - the protective group must be introduced in high yields, without side reactions. - the protected functional groups should be stable under various reaction conditions. - the protective group should be capable of being selectively deprotected under specific conditions that are not adverse to the integrity of the protected compound. A list shows a wide range of protecting agents, from conventional protective groups (TMS, Boc, trityl etc.) to a new special protecting agent, 1,2-bis(chlorodimethylsilyl)ethane1) (which reacts only with primary amines to generate azadisilacyclopentane derivatives) and Teoc-NT2) developed by Sodeoka and Shimizu in 2007. Particularly, Teoc-NT is a useful protecting agent which is stable and easy to handle. It reacts rapidly with various amines, alcohols, and thiols at room temperature to give the corresponding protected compounds in high yields, respectively. The by-product nitrotriazole (NT) has low solubility in the solvent and precipitates out as a crystalline solid. As a result, NT can be removed by simple filtration. The Teoc group can be removed easily by fluoride ions under a neutral condition. Teoc-NT is applicable to the synthesis of various base-sensitive oligonucleotide derivatives. O N TBSO
O
O
NH
N
N
NH2
N
+ Me3Si
NO2
N
O
N TBSO
Teoc-NT (4 eq.)
OTBS
O N
NH
O
N
Et3N (10 eq.)
TBSO
CH2Cl2, rt, 4 h
O
TBSO
B0643
A2298
N
N
N H
SiMe3
O
N NT (insoluble)
Y. 80%
OTBS
C0274
NO2
+ HN
A1268
A2302 O
CH3 CH3 CH2
Br
CH2 CHCH2
Si
CH2
C CH3
O
O Cl
CH3 CH3
Cl
CH2
O
CH2 CHCH2O C O N O
A2303
A2299
A0480
A1247 CHO
CH2 CHCH2O
C O
CH
CH2CH3
O
CH2 CHCH2
B2379 OCH3 O
OCH3
H
Si CH2CH3 CH2CH3 OCH3
B1128
B1151
B0105
OCH3
B3571
B0411
O
SO2Cl S
SO2Cl S
O
C Cl BF4
N S
CH2Br
C S
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
155
Protection & Derivatization
B0412
B2334
B1257
C0176 B3021
CH2Cl
CH3 CH2
O
Si Cl
CH2O C Cl
B3574
CH3
O
CH2 C O CH2
CH2O C O
CH3
B1483
B3234
B1906
B1688
B1773
tBu
NH
CH3
Si CH3
CH3
CF3
Cl3C C OCH2
N
CH2O C N
Cl
CH3
CH3 C O Si tBu
Si
CH3 CH2CH2
Si
CH3
CH3 CH3
Cl
CH3 N
CH3 CH3
Si CH2CH2 Si CH3
CH3
N CH3
CH3
CH3
B1699
B3563
B1702
B0916
B0988 O
CH3 SiH(CH3)2 (CH3)3SiO
CH3
OSi(CH3)3
B1089
B1969
CH3
B1436
N
CH3
B0995
Cl
CH3
H3C
B3565
O CH3CH3
O
NHNH2
CH3
CH3
O
CH3
B3577
CH3
H3C C O Si
CN
O C O N C
N
C0933
H3C
CH3
C O C CH3
N
CH3
N
N
O C S
CH3
CH3
N
CH3 O
N
O C
Br
SiH(CH3)2
CH3
O
CH3
B1043
B2697
CH3 C
Si O
CH
CH3CH3
OCH3 OCH3
T1525 CH3
CH3 CH3 CH3
CH3 CH3
Si Cl
CH3 C
CH3 CH3
CH3 tBu
Si H
CH3 CH3
B1223
B2898
Si
N
CH3 CH3
O Si C(CH3)3
N
CH3
CH3
CH3
CH3 CH3
C N
B1663
B1496
O
Si O S CF3 O
C1124
Br CH3 H3C
H 3C
H3C C Si
H3C C Si
Cl
H3C
O S CF3
C1573
CH3
CH3
O C OCH2
Cl
CH3 CH3
156
Si
CH3 CH3
Cl
Cl
CH3
C0202
Si CH3
CH3 CH3
CH2CH3 CH Si
O
T0589
CH3
CH3 CH3
CH2O C O N
CH3
C1339
CH C
O O
CH3
O C O C CH3
CH3
T2116
D2262
Cl O
O
CH2O C O N O
C1131 Cl
O
O C O N
O
CH3 CH3
O O2N
O
CH3
Cl3C C O
C1574
CH3
O
NH
C CH3
O
H3C
C1591
CH3O Si
O
C0306
CH3
CH2CH3 CH2CH2OCH2Cl
ClCH2OCH3
Cl
CH2CH3
CH3CH2 Si
Cl
CH2CH3
CH3
Si Cl CH3
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Protection & Derivatization
C2411
D2504
P1277
D2461
Si(CH3)3 (CH3)3Si
O
Si Cl
C Cl
O CH2O
O OCH2
D2334
O
O O
CH2O C OCH2
CH2
O
Cl
D1547 D3878 D3879 D3880
C O C
O
Cl
Si(CH3)3
P1281
CH2
C1600
t
D3135
D2469
O
H3C Cl CH3
O
H3C C Si C
BuO C O C OtBu
O
CH3
CF3
C(CH3)3
D0626
C(CH3)3
CH(CH3)2
(CH3)2HC
O
Cl
O S CF3
S O Si O
H3C Cl CH3
D0555
D1608
O
Si O Si Cl
(CH3)2HC
D1612
CH(CH3)2
D2915
O CH3 Cl
C H
CH3
OCH3
Si O Si Cl CH3
CH3
CH3O
CH3
OCH3
D1594
D2159
D0835
CH3
CH3
Si Cl
CH3
CH3
CH3
D1463
N C
C1415 SCl NO2
NO2
S
O P
P Cl
Cl NO2
NO2
C0683
N
Cl
OCH3
F CH3
CH3
C Cl
O
E0478
E0479
E0471
E0105
O O
CH3
CH3 CH3
CH3CH2O C N
Si
O(CH2)2O Si CH3
CH3
CH3
CH3 CH3
CH3
Si
S(CH2)2S
Si
CH3
O O S S CH2CH2 S S O O
CH3
CH3
CH3
CH3
OH
HO
O
T0872
F0239
F0197
I0060
I0303
O
CF3
O
O
O
CH2O C Cl
CH2O C O N
C SCH2CH3
CH3I
CH2 CH3 C OCH3
O
I0324
M0071
M0802
M0676
SO2Cl CH3
CH3
CH3
CH2 C O Si
M2016
SO2Cl
CH2Cl
CH3
NH
CH3
Cl3C C OCH2
OCH3
CH3 CH3
M0680
OCH3
M0681
M1004
OCH3
M1199
M0790
O C CH2Br
CH2CH3
CH3O(CH2)2OCH2Cl
CH2CH3
CH3 CH3
CH3O(CH2)2OCH2 N CH2CH3 Cl
OCH3
Si O C CHCH3
CH3O
C Cl
CH3 OCH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
157
Protection & Derivatization
M0441
M0536
N0142
N0507
N0181
OH SO2Cl
O CH3 CH3 CH3 C N
SO2F
CH2Br
NO2
NO2
NO2
Si CH3 CH3
SCH3
C1400
N0363
P1782 SCl
O O2N
P1378
P1614
O
O C Cl
O CH3
C CH2Br
NO2
CH3
Si
S
O
CH3 O
P0677
P0763
T1485
T0272
C0795 SO2Cl
O
O
O
O CH3
S O S
CH3
SH
HS
(CH3)3C C Cl
CCl3CH2O C Cl
O
O
CH3
T1606
T1689
T0670
CH2CH3 O
CH2CH3 O
CH3CH2
CH2CH3
BF4
T1588
Si O S CF3
O O S S(CH2)3S S O O
CH3
O
CH3
CH3
C OCH2CH2Si(CH3)3
N
CH3
Si
Cl
i Pr
O O
N
(CH3)3SiCH2CH2O C O N
O C OCH2CH2Si(CH3)3 O
O
T1535
Si
CH3
CH3 N
CH3
Si
T1237
O
O
T1467
CH3
(CH3)3SiO
CH3
C CH3
O
T1526 O Cl
C O
Cl3CO
O
CH3 C CH
O
C S Cl
CH3
Si CH3
T1071
O
S O Si CH3
T1573
N
CH3
T0512
i Pr
N
CHN2
CH3
N N
O
Si CH3
CH3
O
CH2CH3
i Pr
CH3
T2591
CH3 CH3
CH
T2590
T1277
NO2
CF3
CH2CH3
S O Si
O
N
T0871
CF3
C N
T1078
O
N
T1146
T0585
N
CF3
O
T2544
N
O
S CF3
CH2CH3 O
O
iPr
OCCl3
CBr
N
CBr 3
Cl O
3
C0308
C Br
158
O
D2390
iPr iPr
CH3CH2 Si
T1468
C Cl
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Protection & Derivatization
Product No. Product Name B0643 A2298 C0274 A1268 A2302 A2303 A2299 A0480 A1247 B2379 B1128 B1151 B0105 B3571 B0411 B0412 B2334 C0176 B3021 B1257 B3574 B1483 B3234 B1906 B1688 B1773 B1699 B3563 B1702 B0916 B0988 B1089 B1969 B1436 C0933 B3577 B0995 B3565 B1043 B2697 T1525 B1223 B2898 B1663 B1496 C1124 C1591 C1573 C1574 C1131 D2262 T2116 C1339 C0202 T0589 C0306 C2411 D2504 P1277 D2461 C1600 P1281 D1547 D3878 D3879 D3880 D2469 D3135
Allyl Bromide Allyl(tert-butyl)dimethylsilane Allyl Chloride Allyl Chloroformate N-(Allyloxycarbonyloxy)succinimide Allyl Phenyl Carbonate Allyltriethylsilane p-Anisaldehyde p-Anisaldehyde Dimethyl Acetal Benzaldehyde 1,2-Benzenedisulfonyl Dichloride 1,3-Benzodithiolylium Tetrafluoroborate [Hydroxyl-Protecting Agent] Benzoyl Chloride 3-Benzoylthiazolidine-2-thione Benzyl Bromide (stabilized with Propylene Oxide) Benzyl Chloride (stabilized withε-Caprolactam) Benzylchlorodimethylsilane Benzyl Chloroformate (30-35% in Toluene) Benzyl Chloroformate Benzyl Isopropenyl Ether [Hydroxyl-Protecting Agent] Benzyl Phenyl Carbonate Benzyl 2,2,2-Trichloroacetimidate Benzyl 2,2,2-Trifluoro-N-phenylacetimidate N,O-Bis(tert-butyldimethylsilyl)acetamide [tert-Butyldimethylsilylating Agent] 1,2-Bis(chlorodimethylsilyl)ethane [Protecting Reagent for Primary Amines] 1,2-Bis[(dimethylamino)dimethylsilyl]ethane [Protecting Reagent for Aromatic Primary Amines] 1,2-Bis(dimethylsilyl)benzene 1,3-Bis(trimethylsilyloxy)propane 9-Bromo-9-phenylfluorene N-tert-Butoxycarbonylimidazole 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 2-(tert-Butoxycarbonylthio)-4,6-dimethylpyrimidine [Boc Agent for Peptides Synthesis] 1-tert-Butoxycarbonyl-1,2,4-triazole tert-Butoxydiphenylchlorosilane (stabilized with CaCO3) tert-Butyl Carbazate tert-Butyl[4-(dimethoxymethyl)phenoxy]dimethylsilane tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent] tert-Butyldimethylsilane 1-(tert-Butyldimethylsilyl)imidazole [tert-Butyldimethylsilylating Agent] tert-Butyldimethylsilyl N-Phenylbenzimidate tert-Butyldimethylsilyl Trifluoromethanesulfonate tert-Butyldiphenylchlorosilane tert-Butyldiphenylsilyl Trifluoromethanesulfonate tert-Butylmethoxyphenylsilyl Bromide tert-Butyl 2,2,2-Trichloroacetimidate N-Carbobenzoxyoxysuccinimide Carbonic Acid Benzyl 4-Nitrophenyl Ester Carbonic Acid tert-Butyl Phthalimido Ester Carbonic Acid tert-Butyl 2,4,5-Trichlorophenyl Ester N-(2-Chlorobenzyloxycarbonyloxy)succinimide Chlorodiethylisopropylsilane Chloro(dimethyl)thexylsilane 2-(Chloromethoxy)ethyltrimethylsilane (stabilized with Diisopropylethylamine) Chloromethyl Methyl Ether Chlorotriethylsilane Chlorotrimethylsilane Chlorotris(trimethylsilyl)silane 2-Chlorotrityl Chloride Diallyl Pyrocarbonate Dibenzosuberyl Chloride Dibenzyl Carbonate Dibenzyl Pyrocarbonate Di-tert-butyl Dicarbonate [Boc-reagent for Amino Acid] Di-tert-butyl Dicarbonate (ca. 30% in Dioxane) Di-tert-butyl Dicarbonate (ca. 30% in Tetrahydrofuran) Di-tert-butyl Dicarbonate (ca. 30% in Toluene) Di-tert-butyldichlorosilane Di-tert-butylsilyl Bis(trifluoromethanesulfonate)
Unit Size 25g 25ml 25g 5g 5g 25ml 25ml 1g
5g 25ml 1g 25g 25g 25ml 25g 1ml 5g 1g 5g
5g 5g 5g 5g 5g 5ml 25g 5g
25g 1g
5ml
5g 25ml 1g 5ml 25g
1g 5g 5ml 25g 5g 25ml
25g
1g 5g 1g 5g 100g 100g 100g 100g 5g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500g 5g 500ml 500g 25g 25g 5g 500ml 500ml 500g 25g 5g 500ml 5g 500g 500g 5g 500ml 250g 5ml 25g 25g 5g 5g 25g 5g 5ml 25g 25g 10g 25g 25g 25g 25ml 250g 5g 100g 5g 5g 5g 25g 100ml 5g 1g 25ml 250g 5g 5g 5g 10g 5g 25g 25ml 500g 25g 500ml 5g 25g 5g 25g 5g 25g 500g 500g 500g 500g 25g 5g
159
Protection & Derivatization
Product No. Product Name D1608 D2334 D0555 D0626 D1612 D2915
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane [Hydroxyl Protecting Agent] 1,3-Dichloro-1,1,3,3-tetramethyldisiloxane 3,4-Dihydro-2H-pyran 2,4-Dimethoxybenzaldehyde 4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent] 4-(Dimethylamino)-1-(triphenylmethyl)pyridinium Chloride
D1594 D2159 D0835 D1463 C1415 C0683 E0478 E0479 E0471 E0105 T0872 F0239 F0197 I0060 I0303 I0324 M0071 M0802 M0676 M2016 M0680 M0681 M1004 M1199 M0790 M0441 M0536 N0142 N0507 N0181 C1400 N0363 P1782 P1378 P1614 P0677 P0763 T1485 T0272 C0795 T1606
Dimethylisopropylchlorosilane [Dimethylisopropylsilylating Agent] Dimethylthiophosphinoyl Chloride 2,4-Dinitrofluorobenzene 2,4-Dinitrophenylsulfenyl Chloride Diphenylphosphinic Chloride N-Ethoxycarbonylphthalimide [for Peptide Synthesis] Ethylenedioxybis(trimethylsilane) [Protecting Reagent for Aldehydes and Ketones] Ethylenedithiobis(trimethylsilane) [Protecting Reagent for Aldehydes and Ketones] Ethylene Di(thiotosylate) [Protecting Reagent for Active Methylene] Ethylene Glycol S-Ethyl Trifluorothioacetate [Trifluoroacetylating Agent for Peptides Research] N-[(9H-Fluoren-9-ylmethoxy)carbonyloxy]succinimide 9-Fluorenylmethyl Chloroformate [N-Protecting Agent for Peptides Research] Iodomethane (stabilized with Copper chip) Isopropenyl Methyl Ether Isopropenyloxytrimethylsilane [Trimethylsilylating Agent] 2-Mesitylenesulfonyl Chloride 4-Methoxybenzenesulfonyl Chloride 4-Methoxybenzyl Chloride (stabilized with Amylene) 4-Methoxybenzyl 2,2,2-Trichloroacetimidate 2-Methoxyethoxymethyl Chloride (2-Methoxyethoxymethyl)triethylammonium Chloride 4'-Methoxyphenacyl Bromide 1-Methoxy-1-trimethylsilyloxypropene 4-Methoxytrityl Chloride [Hydroxyl Protecting Agent] 4-(Methylthio)phenol N-Methyl-N-trimethylsilylacetamide [Trimethylsilylating Agent] 2-Nitrobenzenesulfonyl Chloride 4-Nitrobenzenesulfonyl Fluoride 4-Nitrobenzyl Bromide 4-Nitrophenyl Chloroformate 2-Nitrophenylsulfenyl Chloride [N-Protecting Agent for Peptides Research] Phenacyl Bromide (Phenylthio)trimethylsilane Phthalic Anhydride Pivaloyl Chloride 1,3-Propanedithiol p-Toluenesulfonic Anhydride p-Toluenesulfonyl Chloride 2,2,2-Trichloroethyl Chloroformate Triethyloxonium Tetrafluoroborate (15% in Dichloromethane, ca. 1mol/L)
T1689 T0670 T1468 T1078 T1588 D2390 T1146 T2590 T2591 T2544 T0585 T1277 T1535 T1573 T0871 T1237 T1467 T1071 T1526
Triethylsilyl Trifluoromethanesulfonate 1-(Trifluoroacetyl)imidazole Trifluoromethanesulfonic Acid Diethylisopropylsilyl Ester Triisopropylsilyl Chloride Triisopropylsilyl Trifluoromethanesulfonate Trimethylene Di(thiotosylate) [Protecting Reagent for Active Methylene] Trimethylsilyldiazomethane (ca. 10% in Hexane, ca. 0.6mol/L) 1-[2-(Trimethylsilyl)ethoxycarbonyloxy]benzotriazole N-[2-(Trimethylsilyl)ethoxycarbonyloxy]succinimide 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate N-Trimethylsilylimidazole [Trimethylsilylating Reagent] N-(Trimethylsilyl)morpholine 3-Trimethylsilyl-2-oxazolidinone [Trimethylsilylating Reagent] 4-Trimethylsilyloxy-3-penten-2-one Trimethylsilyl Trifluoromethanesulfonate [Trimethylsilylating Agent] Triphenylmethanesulfenyl Chloride Triphosgene 4,4',4''-Tris(benzoyloxy)trityl Bromide [Hydroxyl Protecting Agent] 4,4',4''-Tris(4,5-dichlorophthalimido)trityl Bromide [Protecting Reagent for Primary Alcohol]
Unit Size 5g 5g 25ml 25g 5g
(contains 5% Dichloromethane at maximum)
5ml 1g 25g 10g 25g
5g 25g 5g 5g 10ml 25ml 5ml 25g 25g
25ml 5g 1g 25g 25g 10g 25g 25g 25g 25g 25g 5g 25ml 5g 25g 25g
[Ethylating Reagent]
160
5ml
10ml
5g
5g 5g 1g 25ml 5g 5g 25ml 1g 1g 1g 25g 5ml
25g 25g 5g
25g 25g 500ml 500g 25g 5g 25ml 5g 500g 5g 25g 500g 25g 5g 25g 500g 5ml 25g 25g 100ml 500ml 25ml 500g 500g 25ml 5g 500ml 5g 25g 5g 250g 250g 25g 500g 1g 500g 250g 100g 500g 25g 500g 500ml 25ml 25g 500g 250g 100ml 25g 25g 5g 250ml 25g 25g 100ml 5g 5g 5g 100g 25ml 5g 25ml 250g 10g 250g 25g 1g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Protection & Derivatization
Product No. Product Name T0512 C0308
Trityl Bromide Trityl Chloride
Unit Size 25g 25g
100g 500g
References 1) S. Djuric, J. Venit, P. Magnus, 1990, 2) M. Shimizu, M. Sodeoka, 3) Review: York, 1999.
. 1981, , 1787; S. Kojima, K. Akiba, , 1040. . 2007, , 5231. 3rd ed., ed. by T. W. Greene, P. G. M. Wuts, John Wiley & Sons, New
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
161
Silicon Compounds for Organic Synthesis
Silicon Compounds for Organic Synthesis Silicon is an element belongs to Group 14 of the Periodic Table and thus has properties similar to carbon. A silicon atom can form a σ-bond to a carbon atom and thereby form a variety of organic silicon compounds. However, as carbon belongs to period II and silicon to period III, the two element’s atoms differ in atomic size, ionization energy, electronegativity, and atomic orbital configuration amongst other things. These differences cause organic silicon compounds to exhibit characteristic reactivities that are not found in carbon compounds. Silylenol ethers, hydrosilanes, Peterson type reagents, silylcyanides, silyldiazomethane and others are increasingly being used in organic syntheses, not only for their protective moieties, but also as reagents of general interest.
A2298
A1326
CH3 CH3 Si
CH3 C
A0927
CH2
ClCH2 Si
CH3 CH3
CH2CH
CH2
CH3
Si
CH2CH3 OCH2CH
CH2
CH3CH2 Si
CH3
CH3
A0729
A1858
CH3
CH3 CH2CH
A2299
B2334
CH(CH3)2
CH2CH
CH2
(CH3)2CH Si
B1856
CH2CH
CH2
CH(CH3)2
CH2CH3
B1728
B1906 t
Bu
CH3 CH3
Si
CH3 CH2CH
CH2
CH2
CH3
CH3
CH3
Si Cl
CH2
CH3
Si
CH2NH
CH3
Si CH3
N
CH3
CH3
Si CH3
CH3
CH3
CH3 C O Si tBu CH3
B1688
B1813
B1699
B2004
B0511 CH3
CH3 Cl
Si
CH2CH2
Si
CH3
SiH(CH3)2
CH3
CH3 Cl
ClCH2 Si CH2Cl
CH3 SiH(CH3)2
CH3
CH3
CH3
CH3 SCH3 Si CH3 SCH3
Si CH3 N
CH3
CH3 C O Si CH3 CH3
B1090
B3047
CH3 CH3
CH3
Si C C Si CH3 CH3
CH3
B1768
B1298
(CH3)3Si
CH3
Si(CH3)3
CF3O2SO
OSO2CF3
B3563
B1302
CH3
B1857
CH3
O
CH3
O
CH3
Si C C C C Si CH3 CH3
CH3
B1245
(CH3)3SiO
OSi(CH3)3
B0830
CH3
Si CH2
Si CH3
CH3
CH3
B1103 CH3
OSi(CH3)3
CH3 (CH3)3SiO
OSi(CH3)3
CH3
CH3
CH3
O
CH3
Si CH3 N
Si O S O Si CH3 CH3
OSi(CH3)3
O
CF3
CH3
C O Si CH3
CH3 CH3
Si
O
CH3
NH C NH
CH3
Si CH3 CH3
CH3
B1695
B1892
CH3 CH3
CH3
162
B1654
CH3
Si CH3
CH2Br
CH3
Si Br CH3
B1769
CH3
CH3
CH3
Br
Si CH2 C CH2
B1087
CH3
Si
CH3 Br C C CH2Br
CH3
Availability, price or specification of the listed products are subject to change without prior notice.
CH3
Si CH3
C CH2
Silicon Compounds for Organic Synthesis
B1436
B3577
H3C
B0995
Cl
CH3 C
Si O
CH
CH3CH3
H3C
B1223
T1525
CH3 CH3
CH3CH3
H3C C O Si
B3565
OCH3
CH3 C
OCH3
CH3 C
CH3 CH3
B2898
CH3 CH3
CH3 CH3
Si Cl
Si H
CH3 C
D2262
O
CH3 CH3
CH3 CH3
B1663
O O S CF3
Si
C1492
Br CH3 H3C
H 3C
H3C C Si H3C
T2116
CH3
CH3
Si Cl
CH3
CH3
C1419
Si
Cl
Si
H3C Cl CH3 CF3
C(CH3)3
O
H3C Cl CH3
D2403
CH3
C(CH3)3
CH3
Si CH3
O
D3761
Cl
CH3
Si
D3386
OCH3
Si Cl
Si CH3
CH3
OCH3
CH3 CH3
CH(CH3)2
Si O Si Cl
(CH3)2HC
Cl
Cl
D3883
Si
Si Cl
CH3 CH3
CH(CH3)2
D1789 OSO2CF3
OCH2CH3 CH3
OCH3
Si H
CH3CH2SiH2CH2CH3
CH3
OCH2CH3
Si(CH3)3
Si CH CH2 OCH3
CH3O OCH3
D2196
D2934
D2935
CH3
CH3
Si H
N
CH3
CH3 Si CH3
T1584
CH3
N
CH3
CH3
Si CH3
O CH2
O Si CH3
CH3
CH3 OCH3
D2406 D2820
Si CH
C OCH2CH3
SiH2
CH2
Si Cl
CH3
F0518
CH3
CH3 O(CH2)2O Si
D1390
CH3 CH3
CH3 H
CH3
E0478
CH3
Si
CH3
H0638
H0089
CH3 CH3
F CH2 C
Si CH3
CH3
D2144
(CH3)2HC
Cl CH3
CH3
C1982
D1608
O
OCH
CH3
C0306
ClCH2
O S CF3
S O Si
ClCH2 Si
Cl
D0358
O
CH3
CH3
Si CH2Cl
CH3
CH3
D3135
CH(CH3)2
C1370
CH3
OCH2CH3
D2469
CH2CH3
CH3
OCH2CH3
H Si Cl
Cl CH2CH2OCH2Cl
OCH2CH3 ClCH2 Si
Cl
C1358
C0862
CH3
H3C C Si C
CH3
CH3 CH3
CH3
CH Si
CH3
CH3 CH3 CH C
CH(CH3)2
CH2CH3
CH3 CH3
C1339
C1402
Si CH2Cl
C CH3 CH3
O
H3C
D1147
CH3O Si
O O S CF3
H3C C Si
Cl
CH3
Si
Si CH3
CH3 CH3
CH3 CH3
CH3
Si NH Si CH3 CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
CH3
163
Silicon Compounds for Organic Synthesis
H0091
I0449 CH3
CH3
I0324
CH3
CH3 CH3
Si O Si CH3 CH3
H0915
Si
CH3 CH2I
M0759
CH3
M1882
CH3
Si CH2OCH3 CH3
D1825
Si
N
H
CH3
Si
O Si CH3
CH3
CH3
(CH3)3Si
P1172
P1250
OSO2CF3
OSO2CF3 Si
CH3
OCH3
M1883
CH2
CH3 CH3
CH3
CH3
OCH3
Si
Si
CH3 CH3
Si(CH3)3
CH CH OCH3
CH3
N
M1077
Si(CH3)3
CH3
CH3
Si
OSO2CF3
OSO2CF3
M1460
CH3
CH3 Li
M1885
OSi(CH3)3
N
CH3
CH3
M1884
CH2 C
CH3
CH3
CH2 C O Si
CH3
CH3
M1264
CH3
Si(CH3)3
CH3
SCH2
N
Si
O CH3
CH3
CH3
CH3
S CH2
Si
O
CH3
CH3
CH3
P1280
H0893
CH2
S0421
CH3
C O Si CH3
CH3 CH3
Si
CH3
T2043
CH3 K
CH3
S CF3
T1078
CH2CH3 CH
H Si
CH2CH3
CH3
T1588 i Pr i Pr
Si
iPr
iPr
i Pr
T0801
CH3 CH3
Si N3 CH3
CH3
Si
CH3
C OH
CH3
CH3
Si CH3 CH3
C CH
T0492
CH3
CH3 CH3
Si CH3
T1146
Si CN
H
Pr
CH3
O CH2
CH3
CH3 CH3
i
T1239
CH3 CH3
Pr
Si
(CH2)5CH3
CH3
T2284
i i Pr
CH3(CH2)5 Si H
CH3
CH3 C NH Si
O
T0990
CH2CH3
T1684
O
CH3CH2 Si H
T1533
CH3
O
Si O S CF3
Cl
(CH2)5CH3
Si CH3
Cl
CH2CH3
Si Cl
T0590
iPr
Cl
Si Cl
T1334
CF3
Cl
Cl CH2 CH
Cl
CH3
CH3
Cl CH3
T0662
Cl
S O Si O
CH2CH3 O
CH3 N Si
CH3 Na CH3
T1570
O CF3
Si
Cl
Si Cl
T1468
O
CH3
T0407
Cl
CH2CH3 O
NCS
NCS
Cl CH3
(CH2)3CH3
CH3CH2 Si
SCN Si
T0636
CH3
NCS CH3
T0398
(CH2)3CH3 CH3(CH2)3 Si H
164
CH3 N Si
M0450
T1689
H0894
Si
CHN2
CH3
Availability, price or specification of the listed products are subject to change without prior notice.
CH3
Si N CH3
CH2CH3 CH2CH3
Silicon Compounds for Organic Synthesis
T0591
T1514 S
CH3 CH3 Si N CH3 CH3
CH3
T1510
T1441
Si
T2544
CH3
CH3
Si
CH3
CH2CH2OH
P CH2OCH2CH2 Si CH3 CH3
CH3
CH3
NO2
N
CH3
CH3
S
T1458
Cl
N
N
C OCH2CH2Si(CH3)3 O
T0585
I0308
T1106
T1213
N CH3
CH3
CH3
N
P CH2CH2 Si CH3
CH3
CH3
CH3
Si
CH3
Si
CH3
I
Si
CH3 NCO
CH3
Si
CH3
CH3
CH2SH
CH3
CH3
I
T1250
T1184
T1451
T1579
T1277 CH3
CH3
Si
CH3
CH3
CH3 CH2OH
CH3
Si
CH2N3
CH3
Si
CF3
CH3
CH3
CH3
CH2MgCl
O
CH3
S OCH2
Si CH3
O
CH3
CH3
Si
CH3
N O
T2465
T2466
T1535
Si(CH3)3
N Si(CH3)3
T1536
O Si
CH3 CH3
O
O Si CH3
T1500
Si CH3
CH2 CH
CH3
CH3
T2746
(CH3)3SiO
T2089
C CH3
T1498
Si(CH3)3
CH3CH2CH2 C C Si CH3 CH3
T1299
T0871
N CH3
CH3 P CH2C C Si CH3
S
CH3
CH3
CH3
OSO2CF3
CH3
O
CH3 C CH
Si C C CH2OH
O Si CH3
C CH2
O
CH3
CH3 CH3 C C
CH3
OSi(CH3)3
CH3
CH3
CH3
T1123
O
Si CH3
T1573
CH3
T1556
CH3
OSO2CF3
OSO2CF3
T1648
T1469
Si
O CH3
CF3
CH3
CH3
S O Si CH3 O
CH3
Br
T0939
T0661
T2467
T1639
P1248
OSO2CF3 Si(CH3)3
O
(CH3)3SiO Si Cl
Si
C CH OSi(CH3)3
H (CH3)3Si CF3O2SO
P1217
OSi(CH3)3
OSi(CH3)3
OSO2CF3 Si(CH3)3
T1463
Si(CH3)3
OSi(CH3)3 (CH3)3SiO
(CH3)3SiO
(CH3)3SiO P
P
(CH3)3Si OSi(CH3)3
Si H Si(CH3)3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
165
Silicon Compounds for Organic Synthesis
Product No. Product Name A2298 A1326 A0927 A2299 A1858 A0729 B2334 B1856 B1728 B1906 B1688 B1813 B1699 B2004 B0511 B1090 B3047 B1298 B1302 B1857 B1768 B3563 B1245 B0830 B1103 B1695 B1892 B1087 B1654 B1769 B1436 B3577 B0995 B3565 T1525 B1223 B2898 B1663 D2262 C1492 D1147 T2116 C1339 C1358 C1370 C1419 C1402 C0862 C0306 C1982 D2469 D3135 D0358 D1608 D2144 D2403 D3761 D3386 D3883 D1789 D2196 D2934 D2935 D1390 D2406 D2820 E0478 T1584
166
Allyl(tert-butyl)dimethylsilane Allyl(chloromethyl)dimethylsilane Allyloxytrimethylsilane Allyltriethylsilane Allyltriisopropylsilane Allyltrimethylsilane Benzylchlorodimethylsilane Benzyltrimethylsilane N-Benzyltrimethylsilylamine N,O-Bis(tert-butyldimethylsilyl)acetamide [tert-Butyldimethylsilylating Agent] 1,2-Bis(chlorodimethylsilyl)ethane [Protecting Reagent for Primary Amines] Bis(chloromethyl)dimethylsilane 1,2-Bis(dimethylsilyl)benzene Bis(methylthio)(trimethylsilyl)methane N,O-Bis(trimethylsilyl)acetamide Bis(trimethylsilyl)acetylene 3,3'-Bis(trimethylsilyl)biphenyl-4,4'-diyl Bis(trifluoromethanesulfonate) 1,4-Bis(trimethylsilyl)-1,3-butadiyne Bis(trimethylsilyl) Malonate Bis(trimethylsilyl)methane 1,2-Bis(trimethylsilyloxy)cyclobutene 1,3-Bis(trimethylsilyloxy)propane Bis(trimethylsilyl) Sulfate N,O-Bis(trimethylsilyl)trifluoroacetamide N,N '-Bis(trimethylsilyl)urea (2-Bromoallyl)trimethylsilane (Bromomethyl)trimethylsilane Bromotrimethylsilane 3-Bromo-1-(trimethylsilyl)-1-propyne (1-Bromovinyl)trimethylsilane tert-Butoxydiphenylchlorosilane (stabilized with CaCO3) tert-Butyl[4-(dimethoxymethyl)phenoxy]dimethylsilane tert-Butyldimethylchlorosilane [tert-Butyldimethylsilylating Agent] tert-Butyldimethylsilane tert-Butyldimethylsilyl Trifluoromethanesulfonate tert-Butyldiphenylchlorosilane tert-Butyldiphenylsilyl Trifluoromethanesulfonate tert-Butylmethoxyphenylsilyl Bromide Chlorodiethylisopropylsilane Chlorodiisopropylsilane Chlorodimethylphenylsilane Chloro(dimethyl)thexylsilane 2-(Chloromethoxy)ethyltrimethylsilane (stabilized with Diisopropylethylamine) Chloromethyl(dichloro)methylsilane (Chloromethyl)dimethylisopropoxysilane Chloromethyldimethylphenylsilane (Chloromethyl)triethoxysilane (Chloromethyl)trimethylsilane Chlorotrimethylsilane Cyclohexyl(dimethoxy)methylsilane Di-tert-butyldichlorosilane Di-tert-butylsilyl Bis(trifluoromethanesulfonate) Dichlorodimethylsilane 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane [Hydroxyl Protecting Agent] 1,2-Dichlorotetramethyldisilane Diethoxymethylsilane [Hydrosilylating Reagent] Diethylsilane Dimethoxymethylvinylsilane 4,5-Dimethoxy-2-(trimethylsilyl)phenyl Trifluoromethanesulfonate Dimethylketene Methyl Trimethylsilyl Acetal Dimethylphenylsilane 2-(Dimethylsilyl)pyridine 2-(Dimethylvinylsilyl)pyridine Diphenylmethylchlorosilane Diphenylsilane Diphenylsilane Ethylenedioxybis(trimethylsilane) [Protecting Reagent for Aldehydes and Ketones] Ethyl (Trimethylsilyl)acetate
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size
25ml 5ml
5g
10ml 5g 1g 1g
1g 5g 5g 5ml
5ml
1g 5g 25ml 1g 1g 5ml
5g
25g
5ml
5g 25ml 1g 1g 5ml 5g 5ml 5ml 5g 25ml 25ml 25ml 5g 1g 25ml 5g 5g 5ml 25g 1g 5ml
5g 5g 5g
5g 5g 25ml 5g 5g 250ml 5g 25ml 5g 5g 25g 10g 5ml 1g 100ml 25g 5g 5g 5ml 10ml 5g 25g 25g 25ml 25g 5g 25g 250ml 5g 5g 25ml 5g 100g 5g 25g 100ml 5g 1g 5g 25ml 25ml 25g 25ml 25g 25ml 25g 10g 250ml 500ml 500ml 25g 5g 500ml 25g 25g 25ml 25ml 250g 5g 25ml 25ml 1g 1g 25ml 25g 25g 25g 25g
Silicon Compounds for Organic Synthesis
Product No. Product Name F0518 H0638 H0089 H0091 I0449 I0324 H0915 M1264 M0759 M1884 M1885 M1077 D1825 M1460 M1883 M1882 P1172 P1250 P1280 H0893 S0421 H0894
(1-Fluorovinyl)methyldiphenylsilane Hexamethyldisilane 1,1,1,3,3,3-Hexamethyldisilazane Hexamethyldisiloxane (Iodomethyl)trimethylsilane Isopropenyloxytrimethylsilane [Trimethylsilylating Agent] Lithium Hexamethyldisilazide (29% in Tetrahydrofuran, ca. 1.6mol/L) Methoxymethyltrimethylsilane 1-Methoxy-3-(trimethylsilyloxy)-1,3-butadiene 3-Methoxy-2-(trimethylsilyl)phenyl Trifluoromethanesulfonate 4-Methoxy-2-(trimethylsilyl)phenyl Trifluoromethanesulfonate N-Methyl-N,O-bis(trimethylsilyl)hydroxylamine Methyldiphenylsilane Methylenebis[dimethyl(2-pyridyl)silane] 2-Methyl-6-(trimethylsilyl)phenyl Trifluoromethanesulfonate 4-Methyl-2-(trimethylsilyl)phenyl Trifluoromethanesulfonate (Phenylthiomethyl)trimethylsilane Phenyl Trimethylsilylmethyl Sulfone 1-Phenyl-1-trimethylsilyloxyethylene Potassium Hexamethyldisilazide (11% in Toluene, ca. 0.5mol/L) Silicon Tetraisothiocyanate Sodium Hexamethyldisilazide (contains 2-Methyl-2-butene) (38% in Tetrahydrofuran,
T0636 T2043 M0450 T0398 T0407 T0662 T1689 T1468 T1570 T1334 T1533 T1078 T1588 T0590 T1684 T1239 T0801 T0990 T2284 T1146 T0492 T0591 T1514 T1441 T1458 T2544 T1510 T0585 I0308 T1106 T1213 T1250 T1184 T1451 T1579 T1277 T2465 T2466 T1535 T1469 T1556 T1648 T1536 T1573 T2746 T2089
Tetrachlorosilane Tributylsilane Trichloro(methyl)silane Trichlorosilane Trichlorovinylsilane Triethylsilane Triethylsilyl Trifluoromethanesulfonate Trifluoromethanesulfonic Acid Diethylisopropylsilyl Ester (Trifluoromethyl)trimethylsilane [Trifluoromethylating Reagent] Trihexylsilane Triisopropylsilane Triisopropylsilyl Chloride Triisopropylsilyl Trifluoromethanesulfonate N-Trimethylsilylacetamide Trimethylsilylacetic Acid Trimethylsilylacetylene Trimethylsilylazide Trimethylsilyl Cyanide 5-(Trimethylsilyl)-1,3-cyclopentadiene Trimethylsilyldiazomethane (ca. 10% in Hexane, ca. 0.6mol/L) N-(Trimethylsilyl)diethylamine N-(Trimethylsilyl)dimethylamine 2-Trimethylsilyl-1,3-dithiane 2-(Trimethylsilyl)ethanol 2-(Trimethylsilyl)ethoxymethyltriphenylphosphonium Chloride 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate (2-Trimethylsilylethyl)triphenylphosphonium Iodide N-Trimethylsilylimidazole [Trimethylsilylating Reagent] Trimethylsilyl Iodide (stabilized with Aluminum) Trimethylsilyl Isocyanate Trimethylsilylmethanethiol Trimethylsilylmethanol Trimethylsilylmethyl Azide Trimethylsilylmethylmagnesium Chloride (20% in Ethyl Ether, ca. 1mol/L) (Trimethylsilyl)methyl Trifluoromethanesulfonate [Trimethylsilylmethylating Reagent] N-(Trimethylsilyl)morpholine 1-(Trimethylsilyl)-2-naphthyl Trifluoromethanesulfonate 3-(Trimethylsilyl)-2-naphthyl Trifluoromethanesulfonate 3-Trimethylsilyl-2-oxazolidinone [Trimethylsilylating Reagent] 2-Trimethylsilyloxy-1,3-butadiene 1-(Trimethylsilyloxy)cyclohexene 1-(Trimethylsilyloxy)cyclopentene 2-(Trimethylsilyloxy)furan 4-Trimethylsilyloxy-3-penten-2-one 1-(Trimethylsilyl)-1-pentyne 2-(Trimethylsilyl)phenyl Trifluoromethanesulfonate
Unit Size 10ml
1g 10ml 100ml 25ml 5ml 100ml
1g 1g 1ml
1g 1g 1g 100ml
ca. 1.9mol/L)
25g
5g
5ml 5ml
5ml 25ml 10ml
100ml 100g 5g 25g 25g 25g 25ml 5g 1g 5g 25ml 25ml 5g 1g 25ml 100ml 1g 25ml
5g 5ml 5g 1g 25g 5g 5g 1ml
5ml 1g
1g
5g 5ml 1g 1g 5ml 10ml 5g
1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 100ml 500ml 500ml 10g 25ml 500ml 5ml 5ml 5g 5g 5ml 25ml 100mg 5g 5g 5ml 5g 10ml 500ml 5g 500ml 500g 25g 500g 500g 500g 250ml 25g 5g 25g 10g 100ml 250ml 25g 25g 5g 250ml 25g 500ml 5g 100ml 25ml 25ml 25g 25ml 25g 5g 5g 100g 25g 25g 1ml 25ml 5g 100ml 25g 25ml 5g 5g 5g 25ml 25ml 10ml 25g 25ml 5g 5g
167
Silicon Compounds for Organic Synthesis
Product No. Product Name T1123 T1500 T1498 T1299 T0871 T0939 T0661 T2467 T1639 P1248 P1217 T1463
1-(Trimethylsilyl)-1-propyne 3-Trimethylsilyl-2-propyn-1-ol (3-Trimethylsilyl-2-propynyl)triphenylphosphonium Bromide 2-Trimethylsilylthiazole Trimethylsilyl Trifluoromethanesulfonate [Trimethylsilylating Agent] Triphenylchlorosilane Triphenylsilane 1,3,5-Tris[4-(trifluoromethanesulfonyloxy)-3-(trimethylsilyl)phenyl]benzene Tris(trimethylsilyloxy)ethylene Tris(trimethylsilyl) Phosphate Tris(trimethylsilyl) Phosphite Tris(trimethylsilyl)silane (stabilized with TBBP) [Reducing Reagent]
Other general silicon compounds are listed on our website. Please refer to it. [http://www.tokyokasei.co.jp/product/chemicals-class/C027.shtml]
168
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 5ml
5g
25ml 1g 1ml 25g 5g
5g 5g 5ml 5ml
100ml 5ml 5g 5ml 250g 25g 25g 1g 25g 25g 25ml 25ml
Sulfur Compounds for Organic Synthesis
Sulfur Compounds for Organic Synthesis Although a sulfur atom belongs to the same group 16 as an oxygen atom in the periodic table, it has specific properties which an oxygen atom does not. For example, the features of a sulfur atom include the following: the lone pair of a divalent sulfur atom has a soft and strong nucleophilicity but it has a weak affinity for hard acids such as a proton; the carbon-sulfur bond can be easily cleaved in various reactions; and it has a variety of atomic valences, etc. Organic sulfur compounds play important roles in organic synthetic chemistry because of the variety of their features. We introduce the following three examples of the role of sulfur compounds as reaction reagents in organic synthetic chemistry: (1) Oxidizing agents By the Swern oxidation and the Corey-Kim oxidization using DMSO, primary and secondary alcohols can be oxidized to aldehydes and ketones, respectively. In the Corey-Kim oxidation, dodecyl methyl sulfides can be used to prevent the offensive odor of dimethyl sulfide.1)
CH3
OH
1) C12H25SCH3 (D3767) (3 eq.) NCS (3 eq.) Toluene, -40ºC
H
CH3 H
CH3
H
H
CH3
2) Et3N (5 eq.)
H O
O
O
H Y. 97%
(2) C-C bond formation in the alpha position When 1,3-dithiane is treated with alkyllithium, an anion is generated in the C-2 position. The alkyl halide A reacts with this to give a monoalkylated 1,3-dithiane. Furthermore, by the same treatment, alkyl halide B reacts with this to give a dialkylated 1,3-dithiane. Therefore, two units, A and B, can be combined with a methylene unit.2) In addition, the dithioketal can be also obtained by protecting the ketone with 1,3-propanediol. It means that umpolung has occurred since the carbonyl carbon was originally positively-polarized. CH3
THF-HMPA (10:1) -78°C 5 min then rt 20 min
S D0119
THF-HMPA (10:1) -78°C 20 min then rt 20 min
CH3
S
C5H11
t-BuLi (1.5 eq.)
S
THF-HMPA (10:1) -78°C 20 min
C5H11 (1.6 eq.) THF-HMPA (10:1) -78°C 60 min then reflux 30 min
Y. 95%
CH3 C5H11
I
(1.1 eq.)
t-BuLi (1.5 eq.)
S
CH3 I
C5H11
S
S
H2, Raney-Ni
CH3 C5H11
i-PrOH reflux, 16 h
CH3 C5H11
CH3 C5H11
Y. 94%
Y. 88%
(3) Leaving groups Functional sulfur groups can be removed by treatment with reducing agents. Dithioketal shown in the examples above can be changed into methylene by reacting with hydrogen in the presence of the Raney-nickel catalyst. The modified Julia olefination is also known as the reductive elimination reaction of sulfones, and it is widely used for the total synthesis of natural products as a stereoselective olefin synthesis.3) selectivity varies with the type of aryl sulfone to be employed. Aryl sulfone is synthesized from the corresponding arylthiol. If ArSH is 2-mercaptobenzothiazole, the reaction is selective, but in the case of 2-mercaptopyridine, it becomes -selective.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
169
Sulfur Compounds for Organic Synthesis
Ar
NaH
R1
S
ArSH
+
R1 CH2Br
H2O2, cat. [W]
Ar
R1
S O O
S
Base
R1 CH CH R2
+ R2 CHO
N
N
ArSH =
N SH
SH
N N
SH
Ph
CF3
N
CF3
SH
In this section, we introduced the sulfur compounds used mainly in organic synthesis as reagents. We provide the building blocks, such as thiophenes and thiazoles, which can be found by a structure or keyword search on our website.
B3360
D0538 S
D1114
S N
Disulfides
O
CH3 CH3
S
O
N S S
S
N
S
S
N
D2477
N
S S
N
Product No. Product Name B3360 D0538 D1114 D2477
Unit Size
Bis(2-methyl-3-furyl) Disulfide 2,2'-Dibenzothiazolyl Disulfide 2,2'-Dipyridyl Disulfide [for Peptide Synthesis] 4,4'-Dipyridyl Disulfide
5g
A1341
B1650 S CH2N3
CH3S OCH3
CH2 CH3S
CH3S
B1378
B2004
B1444
B0907
CH3 SCH3
SCH3 NO2
CH3S
B1709
CH3S
Sulfides
C1601
H3C(H2C)3
CH3 Si
SCH2S
CH3 SCH3
D3992
H0871
CH3
(CH2)3CH3
CH3(CH2)3 Sn S Sn (CH2)3CH3 H3C(H2C)3
D0119
5g 500g 250g 25g
25g 25g 5g
CH3
(CH2)3CH3
D3767
Si
CH3 S Si
CH3
CH3
CH3
B1411
SCH2Cl S S CH3
170
CH3S
O P OCH3 OCH3
O
S CH3(CH2)11SCH3 S
Availability, price or specification of the listed products are subject to change without prior notice.
CH3S
O CN
CH3
Sulfur Compounds for Organic Synthesis
D1648
D2105
P1085
I0461
M1216
O S S
S O C OCH2CH3
P0753
S
O
O
C OCH2CH3
P1602
CH3 S
P1172
T2578 S
CH3 SCH2
OH
Si
CH3
S
CH3
OCH3
CH3
T1514
SCH2CN
S
S
CH3
S
O
CH3
CH3 Si
CH3
CH3
CH3
CH3
S
T2579 CH3 CH3
S
CH3
Product No. Product Name A1341 B1650 B1709 B1378 B2004 B1444 B0907 H0871 C1601 D3992 D0119 D3767 B1411 D1648 D2105 P1085 I0461 M1216 P0753 P1602 P1172 T1514 T2578 T2579
Unit Size
Azidomethyl Phenyl Sulfide 1,1-Bis(methylthio)ethylene 1,3-Bis(methylthio)-2-methoxypropane 1,1-Bis(methylthio)-2-nitroethylene Bis(methylthio)(trimethylsilyl)methane Bis(phenylthio)methane Bis(tributylstannyl) Sulfide Bis(trimethylsilyl) Sulfide Chloromethyl p-Tolyl Sulfide Dimethyl 1,3-Benzodithiol-2-ylphosphonate 1,3-Dithiane Dodecyl Methyl Sulfide Ethyl 3,3-Bis(methylthio)-2-cyanoacrylate Ethyl 1,3-Dithiane-2-carboxylate Ethyl 1,3-Dithiolane-2-carboxylate Ethyl (Phenylthio)acetate Isobutylene Sulfide Methoxymethyl Phenyl Sulfide (Phenylthio)acetic Acid (Phenylthio)acetonitrile (Phenylthiomethyl)trimethylsilane 2-Trimethylsilyl-1,3-dithiane (1R,4R,5R)-4,7,7-Trimethyl-6-thiabicyclo[3.2.1]octane (1S,4S,5S)-4,7,7-Trimethyl-6-thiabicyclo[3.2.1]octane
B1322
1g 1g 25g 5g 1g 5g
5g 5g 25g 1g 5g 5g 5ml 25g
5g 1g 1g
B1505
B2656 SH
SH
5g 5g 5g 250g 1g 25g 5g 25g 5g 1g 25g 25g 500g 5g 25g 25g 25ml 5g 250g 5g 5ml 25g 5g 5g
SH
SH
Thiols SH
HS
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
SH
171
Sulfur Compounds for Organic Synthesis
B2391
B2655 SH
E0032 Br
CF3
P0640
HS
HS
S
SH
P0763 N
N
SH
HS CF3
M0246
M0055 M0247
SH
N
T0266
N N
HS
N HS
SH
HS
CH3
Product No. Product Name B1322 B1505 B2656 B2391 B2655 E0032 M0055 M0247 M0246 P0640 P0763 T0266
SH
Unit Size
1,2-Benzenedithiol 1,4-Benzenedithiol 1,3,5-Benzenetrithiol 3,5-Bis(trifluoromethyl)benzenethiol 5-Bromo-1,3-benzenedithiol 1,2-Ethanedithiol 2-Mercaptobenzothiazole 2-Mercaptobenzothiazole 2-Mercaptopyridine 1-Phenyl-5-mercapto-1H-tetrazole 1,3-Propanedithiol Toluene-3,4-dithiol
1g 1g 1g 25g 25g 25g 25g 25g 1g
B2240
C1043
5g
5g 5g 1g 5g 1g 500g 500g 500g 100g 500g 25ml 25g
M0979
CH3 S
NH C CH3
O
O
CH3
Sulfenic Acid Derivatives
Cl
CH3O C SCl
SCl
T1237
C S Cl
Product No. Product Name B2240 C1043 M0979 T1237
Unit Size
N-tert-Butylbenzenesulfenamide Chlorocarbonylsulfenyl Chloride Methoxycarbonylsulfenyl Chloride Triphenylmethanesulfenyl Chloride
1g
D1944
D2113
Thiocarbonyl Compounds
172
N CH3
CH2
CH3
N
S
CH3
S S
25g 25g 25g 10g
M1473
S CH3
5g 5g 5g
Cl
CH3
Availability, price or specification of the listed products are subject to change without prior notice.
O CH2 O
O
S
Sulfur Compounds for Organic Synthesis
P1236
P1056
T0635
S O
B0479
CH3
Cl
S
N
CH3
C SCH2CH
N
CH2
S
S
B0486
S
CH3 N
S
CH3
N C S S C N
CH3
CH3
S
S
CH3
iPr
S i
Pr
N i
S
S
Pr
N
i
Pr
S
CH3
T1320
S
CH3
T1555
S
CH3
S
N C S S C N Cl
CH3
CH3
Cl
Product No. Product Name D1944 D2113 M1473 P1236 P1056 T0635 B0479 T1555 B0486 T1320
Unit Size
Dimethyldithiocarbamic Acid Allyl Ester Dimethylthiocarbamoyl Chloride 5-(Methacryloyloxy)methyl-1,3-oxathiolane-2-thione Phenyl Chlorothionoformate Pyrrolidinodithiocarbamic Acid Allyl Ester Tetrabutylthiuram Disulfide Tetraethylthiuram Disulfide Tetraisopropylthiuram Disulfide Tetramethylthiuram Disulfide Thiophosgene
5g 25g 25g 5g 25g 25g
D0798
M0805
M1148
O
Sulfoxides
CH3
P1135
T2545 O S
S
O
CH3
CH3
CH3
S
S CH3
CH3
O CH3
Fe
Product No. Product Name D0798 M0805 M1148 P1135 T2545 T2546
O
O S
T2546 O
O
S
5g 25g 25g 25g 25g 500g 500g 25g 500g 100g
5g
Dimethyl Sulfoxide Methyl (Methylsulfinyl)methyl Sulfide Methyl Phenyl Sulfoxide Phenylsulfinylacetic Acid Ethyl Ester (R)-(p-Toluenesulfinyl)ferrocene (S)-(p-Toluenesulfinyl)ferrocene
S
CH3
Fe
Unit Size 25g 5g 5g 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500g 25g 25g 5g 5g 5g
173
Sulfur Compounds for Organic Synthesis
B2907
B2908
M1044 CH3
O (CH3)3C S NH2
Sulfinic Acid Derivatives
O
O
O S
(CH3)3C S NH2 CH3
CH3 CH3
M1066 CH3 O O S CH3
CH3 CH3
Product No. Product Name B2907 B2908 M1044 M1066
Unit Size
(R)-(+)-tert-Butylsulfinamide (S)-(-)-tert-Butylsulfinamide (1R,2S,5R)-(-)-Menthyl (S)-p-Toluenesulfinate (1S,2R,5S)-(+)-Menthyl (R)-p-Toluenesulfinate
5g 1g
A1444
B2434
S CH2CH
N
CH2
O
C1304
C2428
ClCH2CH2 S CH2CH2CH2
D0959
Cl
Cl
E0466
O (CH2)7CH3
CH2
O
S CH2CH3
SO2CH2F
S C CH
CH3
O
O
M0875
F0341
O
CH S CH CH2
O
SO2CH3
SO2CH3
C OH
E0427
O
M0401
SO2CH2CN
O
D3161
CH3(CH2)7 S
C1237
O
O
SO2
SO2
O
C1236
SO2CH2CH2Cl O2 S
O2S
S O
B1574
B1573 CH2
O
Sulfones
1g 1g 25g 5g
O
P1250
P0982
D0557
SO2CH2SCH3 O
CH3
S CH2
Si
O
CH3
O CH3
S CH
CH2 O
O
S
O
CH3
Product No. Product Name A1444 B2434 B1573 B1574 C1304 C2428
174
Allyl Phenyl Sulfone 4-Benzylthiomorpholine 1,1-Dioxide cis-1,2-Bis(phenylsulfonyl)ethylene trans-1,2-Bis(phenylsulfonyl)ethylene 2-Chloroethyl Phenyl Sulfone 4-(2-Chloroethylsulfonyl)butyric Acid
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 1g
5g 5g 5g 1g 5g
25g 25g 25g 5g 25g 25g
Sulfur Compounds for Organic Synthesis
Product No. Product Name C1236 C1237 D3161 D0959 E0427 E0466 F0341 M0401 M0875 P1250 P0982 D0557
Unit Size
4-Chlorophenyl Cyanomethyl Sulfone 4-Chlorophenyl Methyl Sulfone Di-n-octyl Sulfone Divinyl Sulfone (stabilized with HQ) Ethyl Phenyl Sulfone Ethynyl p-Tolyl Sulfone Fluoromethyl Phenyl Sulfone Methyl Phenyl Sulfone Methylthiomethyl p-Tolyl Sulfone Phenyl Trimethylsilylmethyl Sulfone Phenyl Vinyl Sulfone 3-Sulfolene
5g 25g 5g 250g 25g 5g 5g 500g 25g 5g 25g 500g
5g 5g
I0758
B0030 B2678
T0267 SO3H
SO3H
SO3H
. H2O
I
. H2O
Sulfonic Acids
25g 10g 1g 1g 25g 5g 1g 5g 25g
. 2H2O CH3
Product No. Product Name B0030 B2678 I0758 T0267
Unit Size
Benzenesulfonic Acid Monohydrate Benzenesulfonic Acid Monohydrate 2-Iodobenzenesulfonic Acid Dihydrate p-Toluenesulfonic Acid Monohydrate
25g 25g 1g 25g
B1931
B1389
C1324
CH3 O
CH3
O
HN SCH3
O
O
SO2 N C SCH3
C1325
C1326
CH3
C1327
CH3
CH3
C1142 CH3
CH3
CH3
O
S O S
Sulfonic Acid Derivatives
500g 500g 5g 500g
S O
C0886
CH3 O
S O
S O O O
O
E0471
M1182
CH3
CH3
S O N C
CH3
O
I0777
CH3
CF3(CF2)7 S
M1186 SO2NH N C
O OCH2CH3
NO2
F
CH3
CH3
SO2Cl
CH3 CH3
O
CH3
S NCO O
H1176
O
Cl
SO2Cl
O S O O
CH3 O O S S CH2CH2 S S O O
Cl
N
N
NH
CH3 SO2Cl
M0071
M1382
N0576
SO2Cl CH3
N0604
T1471
O CH3
O CH3
S O
O
CH2CH2 S Cl SCH3
O
O2N
N
O
S N O
CH3
N
S O(CH2)17CH3 O
CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
175
Sulfur Compounds for Organic Synthesis
T1461
T1562
T0272
T0998
SO2Cl CH3
O
SO2Cl CH3 CH3
CH3
O
CH3 CH3
S
CH3
S CH2NC O
O
D2390 SO2Cl
CH
CH
SK
CH3 CH3
O O S S(CH2)3S S O O
CH3
O CH
CH3
CH3 CH3
Product No. Product Name B1931 B1389 C1324 C1325 C1326 C1327 C1142 C0886 E0471 M1182 H1176 I0777 M1186 M0071 M1382 N0576 N0604 T1471 T1461 T1562 T0272 T0998 T1046 T1185 T0459 D2390
CH3
CH3
T0459
O
S NCO
SO2Cl CH3
T1185
O
O
S NSO
CH3
T1046
Unit Size
Benzenesulfonic Anhydride N-[Bis(methylthio)methylene]-p-toluenesulfonamide (+)-10,2-Camphorsultam (-)-10,2-Camphorsultam (2R,8aS)-(+)-(Camphorylsulfonyl)oxaziridine [Asymmetric Oxidizing Reagent] (2S,8aR)-(-)-(Camphorylsulfonyl)oxaziridine [Asymmetric Oxidizing Reagent] 2-Chloroethanesulfonyl Chloride Chlorosulfonyl Isocyanate Ethylene Di(thiotosylate) [Protecting Reagent for Active Methylene] Ethyl O-Mesitylsulfonylacetohydroxamate [Precursor of the Powerful Aminating Reagent] Heptadecafluoro-1-octanesulfonyl Fluoride N '-Isopropylidene-2-nitrobenzenesulfonohydrazide 2,4-Mesitylenedisulfonyl Dichloride 2-Mesitylenesulfonyl Chloride S-Methyl Methanethiosulfonate 2-(1-Naphthyl)ethanesulfonyl Chloride 1-(4-Nitrobenzenesulfonyl)-1H-1,2,4-triazole Octadecyl p-Toluenesulfonate N-Sulfinyl-p-toluenesulfonamide 2,4,5,6-Tetramethylbenzenedisulfonyl Dichloride p-Toluenesulfonyl Chloride p-Toluenesulfonyl Isocyanate p-Toluenesulfonylmethyl Isocyanide p-Toluenethiosulfonic Acid Potassium Salt 2,4,6-Triisopropylbenzenesulfonyl Chloride Trimethylene Di(thiotosylate) [Protecting Reagent for Active Methylene]
B1517
B3125
5g
25g 5g 5g 5g 5g 5g 500g 500g 25g 25g 250g 5g 25g 500g 25g 5g 5g 5g 5g 5g 500g 500g 25g 25g 500g 25g
1g 1g 1g 1g 25g 25g 5g 5g 25g
1g
5g 25g 1g
1g 25g 25g 5g 5g 25g 5g
B1151 O
SS P P SS
O
Others
S O
S O
B1376
B2188
C1380
S
C1159
BF4
S
O
C1122
CH3 CH3
176
S S S P P S S S
Cl CH3
S N C CH3 CH3
NCN S
(CH2)3Cl
BF4
CF3SCu
Availability, price or specification of the listed products are subject to change without prior notice.
CH3S
NHCH3
Sulfur Compounds for Organic Synthesis
C1390
D2078
D2114
D1945
O S
BF4
CH3
D0797
S
CH3
O S
D2159
CH3
CH3S
D2231
SCH3
D2685
CH3
S
O
SCH3
BF4
C CH2S
D2002
CH3 CH3
BF4
B1133 NH
O CH3O S OCH3
CH3
O
CH3
M1083
S P Cl
P1254
CH3
S
BF4
S
P0998
. H2O
T2136
P
CH3O
S S P
OCH3
S S
T1308
O CH2CH3
. SO3
N S
CH3NHSO3H
CH3CH2
N
N
CH2CH3
. SO3
CH3
S
S
P
P CH3
CH3 CH3
O
T1564
T1833
CH3(CH2)3
O
O
(CH2)3CH3 S
T1065
I
CH3
(CH2)3CH3
S CH3 Br CH3
CH3
S CH3
I
CH3
Product No. Product Name B1517 B3125 B1151 B1376 B2188 C1380 C1159 C1122 C1390 D2078 D2114 D1945 D2231 D0797 D2159 D2685 D2002 B1133 M1083 P1254 P0998 T2136 T1308 T1564 T1833 T1065
Unit Size
Belleau's Reagent [Sulfurating Reagent] 3H-1,2-Benzodithiol-3-one 1,1-Dioxide 1,3-Benzodithiolylium Tetrafluoroborate [Hydroxyl-Protecting Agent] 2,4-Bis(p-tolylthio)-1,3-dithia-2,4-diphosphetane-2,4-disulfide [Sulfurating Reagent] N-tert-Butylbenzenesulfinimidoyl Chloride [Oxidizing Reagent] (3-Chloropropyl)diphenylsulfonium Tetrafluoroborate Copper(I) Trifluoromethanethiolate N-Cyano-N ',S-dimethylisothiourea Cyclopropyldiphenylsulfonium Tetrafluoroborate S,S '-Diethyl Dithiocarbonate S,S '-Dimethyl Dithiocarbonate Dimethyl(methylthio)sulfonium Tetrafluoroborate Dimethylphenacylsulfonium Tetrafluoroborate Dimethyl Sulfate Dimethylthiophosphinoyl Chloride Diphenyl(methyl)sulfonium Tetrafluoroborate S,S-Diphenylsulfilimine Monohydrate Lawesson's Reagent [Sulfurating Reagent] Methylsulfamic Acid N-(Phenylthio)phthalimide Pyridine - Sulfur Trioxide Complex Sulfur Trioxide - Triethylamine Complex Tetramethyldiphosphine Disulfide Tributylsulfonium Iodide Trimethylsulfoxonium Bromide Trimethylsulfoxonium Iodide
1g 10g 1g 1g
1g 1g 25g 1g 1g 1g 25g 5g 5g 25g 5g
25g
5g 5g 5g 25g 5g 1g 5g 25g 1g 10g 5g 5g 5g 500g 5g 5g 5g 250g 25g 25g 500g 25g 5g 1g 25g 500g
References 1) K. Nishide, S. Ohsugi, M. Fudesaka, S. Kodama, M. Node, 2002, 2) D. Enders, T. Schüßeler, , 3746. 3) D. A. Alonso, C. Nájera, M. Varea, . 2004, 2002, 2563.
. 2002,
, 5177.
, 573; Review: P. R. Blakemore,
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
177
Phosphines for Organic Synthesis
Phosphines for Organic Synthesis Phosphorus belongs to group 15 in the periodic table, the same as nitrogen, and it binds with carbon to form various organophosphate compounds. However, since nitrogen belongs to the second-period and phosphorus to the third, they differ in atomic size, ionization energy and electronegativity etc. Therefore, organophosphate compounds show a characteristic reactivity which organic nitrogen compounds do not have, and it is utilized as a versatile reaction reagent in organic synthesis. For example, phosphorus has a high affinity for oxygen: phosphorus ylide and phosphonate are utilized for the Wittig reaction and the Horner-Emmons reaction, respectively, and it extracts oxygen from aldehydes to produce olefins. Phosphine extracts oxygen from alcohols to produce esters in the Mitsunobu reaction. Another feature of phosphine includes bearing a soft lone pair. Therefore, it forms comparatively stable complexes with transition metals such as palladium. This transition metal complex is used frequently as a catalyst in reactions such as the Suzuki-Miyaura cross-coupling reaction and the Heck reaction.1) Although phosphine also has a trigonal pyramidal structure like amines, its rotational barrier energy is considerably higher than the corresponding amine. Therefore, a phosphine which has three different substituents has optical isomers. This optically-active phosphine is utilized for asymmetric syntheses as a P-chiral ligand.2) In this section, we introduce tri-substituted alkyl and aryl phosphines, such as tricyclohexylphosphine and triphenylphosphine.
B3428
F
B2089
F
F
F
F
PCH2CH2P F
F
F F
2
B3449
F
2
B2711
BH3 (CH3)3C P CH3
Fe P
B1174
C(CH3)3 C(CH3)3 C(CH3)3
P Fe P
C(CH3)3
B2383
Fe
PPh2
PPh2
P (CH2)4
P
B1959
P
(CH2)6 P
Fe PPh2
B1960
2
B1112 H
CH3 O
CH2 P
CH3 O
CH2
P
CH3 O
CH2 P
CH3 O
CH2
P
B2867 H N
(CH2)5 P
PPh2
B1138
(C6H5)2P
P(C6H5)2 O
O
178
P
H
B2717
P
P CH2CH2 P
O
B1113
P
P
CH3
P
PPh2
P CH2
PPh2
2
B2027
H
PPh2
PPh2
B1137
CH3
2
P(C6H5)2
PPh2
P 2
B1982
CH3
CH3
B2709 CH3
P
C C
P
P
CH(CH3)2
PPh2 PPh2
B1246
CH3
P
CH3
B1405
P(C6H5)2
H
CH3
CH(CH3)2 CH(CH3)2
B1406
Fe
B2704
B2003
CH(CH3)2
Ph2P
PPh2
B2630
P
BH3 P CH3 C(CH3)3
B3196
B2710
PPh2
Availability, price or specification of the listed products are subject to change without prior notice.
P CH2CH2CH2
P
Phosphines for Organic Synthesis
B3035
B3036 OCH3
C1429
D3940
D3387
OCH3 (CH3)3C
C(CH3)3 PCH2CH2P
PCH2CH2P
CH3O
CH3O
D3834
D2411
C(CH3)3 P
P
P
C(CH3)3
D3388
D3389
D1019 P Et
2
N
N
P
P
P
C(CH3)3
P Et
C(CH3)3
(CH3)2N
D2478
D2537
D2538
D2535
CH3
(CH3)2N
N(CH3)2 PPh2
P
CH3
(CH3)2N Ph2P Fe
(CH3)2N Ph2P
Fe
Fe
Ph2P
PPh2
D3243
CH3
N(CH3)2 PPh2
Fe
D3242
D2536
CH3
D2774
D2775
D2766
O C OH
O C OH
OCH3 P
D2630
OCH3 P(C6H5)2
P(C6H5)2
P
D2404
D2471
E0519
P
I0583
P
CH3 P
P CH2CH2CH3
CH
P CH2CH3
P1176
P
CH3
N
M1318
CH2
P
D2043
T0361
T1912
F F
F
F
F
P CH3
P
T2248
T1643
T1005
O
P
T0519
t Bu
(CH2)7CH3
(CH2)5CH3
CH3(CH2)7 P
CH3(CH2)5 P
P
(CH2)7CH3
(CH2)5CH3
T1789
P
T0503
O
T1757
Bu
Bu
O P
t
P
SO3Na
P
T1165
t Bu
Bu Bu
T2725
T1656 O
OH
Br P 3
P
B 3
P
BH3
. HCl
P Br
HO
P O
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
OH O
179
Phosphines for Organic Synthesis
T1614
T0861
T1024
T1025
T0862
OCH3
CH3
CH3
CH3O
P
P
CH3O
CH3
CH3
P
3
CH3O
T2484
OCH3
CH3
CH3
P P CH3
CH3
CH3
T1666 F
F
S
F
P F
F
S
P S
3
Product No. Product Name B3428 B2089 B2711 B2710 B1174 B3449 B3196 B2383 B1406 B1405 B2630 B2704 B1246 B2709 B1137 B2003 B2027 B1959 B1113 B1112 B1982 B1960 B2717 B2867 B1138 B3035 B3036 C1429 D3940 D3387 D3834 D2411 D3388 D3389 D1019 D2478 D2537 D2538 D2535 D2536 D3242 D3243 D2774 D2775 D2766
1,2-Bis[bis(pentafluorophenyl)phosphino]ethane (S,S)-1,2-Bis[(tert-butyl)methylphosphino]ethane Bis(borane) 1,1'-Bis(di-tert-butylphosphino)ferrocene 1,1'-Bis(diisopropylphosphino)ferrocene 1,2-Bis(dimethylphosphino)ethane (2R,3R)-(-)-2,3-Bis(diphenylphosphino)bicyclo[2.2.1]hept-5-ene (R,R '')-2,2''-Bis(diphenylphosphino)-1,1''-biferrocene (±)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl 2,2'-Bis(diphenylphosphino)biphenyl (2S,3S)-(-)-Bis(diphenylphosphino)butane 1,4-Bis(diphenylphosphino)butane 4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene 1,2-Bis(diphenylphosphino)ethane trans-1,2-Bis(diphenylphosphino)ethylene 1,1'-Bis(diphenylphosphino)ferrocene 1,6-Bis(diphenylphosphino)hexane (2R,3R)-(-)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol (2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol Bis(diphenylphosphino)methane 1,5-Bis(diphenylphosphino)pentane 4,6-Bis(diphenylphosphino)phenoxazine Bis[2-(diphenylphosphino)phenyl] Ether 1,3-Bis(diphenylphosphino)propane (R,R)-1,2-Bis[(2-methoxyphenyl)phenylphosphino]ethane (S,S)-1,2-Bis[(2-methoxyphenyl)phenylphosphino]ethane Cyclohexyldiphenylphosphine Di-tert-butylphenylphosphine 2-(Di-tert-butylphosphino)biphenyl 1-[2-(Di-tert-butylphosphino)phenyl]-3,5-diphenyl-1H-pyrazole Dicyclohexylphenylphosphine 2-(Dicyclohexylphosphino)biphenyl 2-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenyl Diethylphenylphosphine 4-(Dimethylamino)phenyldiphenylphosphine (R)-N,N-Dimethyl-1-[(S)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine (S)-N,N-Dimethyl-1-[(R)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine (R)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine (S)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine 2-(Diphenylphosphino)benzoic Acid 4-(Diphenylphosphino)benzoic Acid (R)-(+)-2-Diphenylphosphino-2'-methoxy-1,1'-binaphthyl (S)-(-)-2-Diphenylphosphino-2'-methoxy-1,1'-binaphthyl 4-Diphenylphosphinomethyl Polystyrene Resin cross-linked with 2% DVB (200-400mesh)
D2630 D2404 D2471
Diphenylpropylphosphine Diphenyl-1-pyrenylphosphine Diphenyl-2-pyridylphosphine
Unit Size 100mg 100mg
100mg 5g 1g 1g 100mg 100mg 5g 1g 10g 1g
5g 1g
5g 100mg 5g 100mg 100mg 5g
1g 1g 1g 1g 1ml 1g
100mg 100mg
(0.5-1.0mmol/g)
180
Availability, price or specification of the listed products are subject to change without prior notice.
100mg
1g 100mg 1g 1g 100mg 100mg 500mg 25g 5g 5g 1g 1g 25g 5g 25g 1g 25g 5g 1g 1g 25g 1g 1g 5g 25g 1g 1g 25g 5g 1g 5g 5g 5g 5g 5ml 5g 100mg 100mg 100mg 100mg 1g 1g 1g 1g 5g 5g 1g 1g
Phosphines for Organic Synthesis
Product No. Product Name E0519 I0583 M1318 P1176 D2043 T0361 T1912 T1165
Ethyldiphenylphosphine Isopropyldiphenylphosphine Methyldiphenylphosphine (Pentafluorophenyl)diphenylphosphine Sodium Diphenylphosphinobenzene-3-sulfonate Tributylphosphine Tri-tert-butylphosphine Tricyclohexylphosphine (contains Tricyclohexylphosphine Oxide)
T2248 T1643 T1005 T0503 T1757 T0519 T1789 T2725 T1656 T1614 T0861 T1024 T1025 T0862 T2484 T1666
Tricyclopentylphosphine Tri(2-furyl)phosphine Trihexylphosphine Tri-n-octylphosphine Triphenylborane - Triphenylphosphine Complex Triphenylphosphine Triphenylphosphine Borane Triphenylphosphine Dibromide Tris(2-carboxyethyl)phosphine Hydrochloride Tris(2,6-dimethoxyphenyl)phosphine Tris(4-methoxyphenyl)phosphine Tris(2-methylphenyl)phosphine Tris(3-methylphenyl)phosphine Tris(4-methylphenyl)phosphine Tris(pentafluorophenyl)phosphine Tri(2-thienyl)phosphine
Unit Size 1g 1g 1g 1g 25ml 25ml 1g 1g
(ca. 18% in Toluene, ca. 0.60mol/L)
25ml 5g 25g
1g
5g 5g 5g 5g 5g 5g 1g 1g
5g 5g 5g 5g 5g 500ml 5g 500ml 5g 5g 25ml 500ml 25g 500g 25g 25g 25g 25g 25g 25g 25g 25g 5g 5g
References 1) Review: D. S. Surry, S. L. Buchwald, . 2008, , 6338. 2) T. Imamoto, J. Watanabe, Y. Wada, H. Masuda, H. Yamada, H. Tsuruta, S. Matsukawa, K. Yamaguchi, 1998, , 1635.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
.
181
Hypervalent Iodine Compounds
Hypervalent Iodine Compounds Iodine is atomic number 53, in the 5th period, Group 17, halogens of the periodic table. Iodine is a large-sized halogen element, easily polarizable, and low in electronegativity. It forms hypervalent organoiodanes beyond the octet theory by readily extending its valence. For example, hypervalent organoiodane with three ligands is a 10-I-3 type compound as shown in the figure. The central iodine atom forms a plane with two lone pairs and one σ-bond, and furthermore, this iodine atom coordinates two ligands with larger electronegativity in an apical position orthogonal to the plane resulting in the formation of a linear three center-four electron bond. The I-L bond in the apical position is weaker and longer than the covalent bond. For example, the I-O bond length in PhI(OAc)2 is longer than the sum of their covalent bond radii (1.99 Å) and these bond lengths have a range of 2.15∼2.16 Å. Apical position
L Ar
I
: :
L
The stability and reactivity of hypervalent organoiodanes exhibit a greater dependence on the character of hypervalent bonds in the apical position. The hypervalent bonds in the apical position are easily cleaved, and the cleavage causes trivalent iodines with 10 electrons to be reduced to monovalent iodines of a more stable octet structure. For this reason, it exhibits good elimination and oxidation rate and finds application in organic syntheses.1∼3) (Diacetoxyiodo)benzene, the most typical trivalent iodine compounds, which is attempted to support the polymers. For example, Togo and coworkers have demonstrated several oxidative functional group conversion reactions using poly[4(diacetoxyiodo)styrene](1).4) After reaction, this polymer-supported reagent can be recovered by filtration and reused after re-oxidation with peracetic acid. Therefore, it is expected to be used as environmentallyfriendly chemical conversion reagent in the near future. OAc I OH R
B2539
R'
N
I
O
C O
I
O C CF3
CF3
time (h)
Y. (%)
4
83
Acetophenone
4
94
B2359
B2121
O
O C O
BF4
N
R'
B1616
O CF3
R
CH3CN, rt
B1175
Product Benzaldehyde
O
OAc 1 , TEMPO
I
CH3
O C CF3
F
F
F
F
CH3 CH3
N
CH3 I
CH3
N
CH3 C OO PF6
CH3
I
O
CH3
O
CH3
F
D2045
D2372
D2503
AcO OAc O AcO I
O C O O
182
D2356
I
Br
D2248
. H2O
I I
Cl
I
Availability, price or specification of the listed products are subject to change without prior notice.
AsF6
Hypervalent Iodine Compounds
D2238
D2373
D2357
D2243
I
I I
I
I
I NO3
PF6
E0467
D2253
P1298
ClO4
P1015
I0330
CF3SO3
I0479 O
HC C
I
O
BF4
HO
I
O
O
O S CH3
HO
I
CH3
O S
O
CH3 C O
O I
O C CH3
O
CH3 C O
I
O C CH3 CH3
CH3
O
CH3
I0072
I0073
I0591 CH3
I
O
HO
n
I
O
CH3
P1080
CH
O
I F
F
F 4
P1082
I
O
O S CF3
CF3CF2CF2
O
I
O S CF3 O
O S CF3
CF3 CF3
CF
I
OSO2CF3
B
P1620
O CF3(CF2)7
I
O
F
P1081
CH3
CF3(CF2)5
F
P1659 O
P1415
T2624
Si(CH3)3
O O C CH3
I
P
CF3
I
O
I
CH3 CH3
O C CH3
CF3SO3
O
P1239 CH3 CH3
Si C C
I
BF4
CH3
Product No. Product Name B2539 B1175 B1616 B2359 B2121 D2045 D2372 D2503 D2356 D2248 D2238 D2373 D2357 D2243 D2253 E0467 P1298 P1015 I0330 I0479 I0072 I0073 I0591 P1080
Bis(pyridine)iodonium Tetrafluoroborate [Bis(trifluoroacetoxy)iodo]benzene [Bis(trifluoroacetoxy)iodo]pentafluorobenzene Bis(2,4,6-trimethylpyridine)iodonium Hexafluorophosphate 1-(tert-Butylperoxy)-1,2-benziodoxol-3(1H)-one Dess-Martin Periodinane Diphenyliodonium Bromide Diphenyliodonium-2-carboxylate Monohydrate Diphenyliodonium Chloride Diphenyliodonium Hexafluoroarsenate Diphenyliodonium Hexafluorophosphate Diphenyliodonium Iodide Diphenyliodonium Nitrate Diphenyliodonium Perchlorate Diphenyliodonium Trifluoromethanesulfonate Ethynyl(phenyl)iodonium Tetrafluoroborate [Ethynylating Reagent] [Hydroxy(methanesulfonyloxy)iodo]benzene [Hydroxy(tosyloxy)iodo]benzene Iodobenzene Diacetate Iodomesitylene Diacetate Iodosobenzene 2-Iodosobenzoic Acid 4-Isopropyl-4'-methyldiphenyliodonium Tetrakis(pentafluorophenyl)borate (Perfluorohexyl)phenyliodonium Trifluoromethanesulfonate
Unit Size 5g 1g 1g
5g 5g 5g
1g
5g 5g 1g
10g
5g 5g 25g 5g
5g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
1g 25g 1g 5g 1g 25g 5g 25g 25g 1g 25g 5g 25g 1g 5g 1g 25g 25g 250g 25g 5g 10g 25g 5g
183
Hypervalent Iodine Compounds
Product No. Product Name P1659 P1081 P1082 P1620 P1415 T2624 P1239
(Perfluoroisopropyl)phenyliodonium Trifluoromethanesulfonate (Perfluoro-n-octyl)phenyliodonium Trifluoromethanesulfonate (Perfluoropropyl)phenyliodonium Trifluoromethanesulfonate Phenyl[2-(trimethylsilyl)phenyl]iodonium Trifluoromethanesulfonate Poly[4-(diacetoxyiodo)styrene] 1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole Trimethylsilylethynyl(phenyl)iodonium Tetrafluoroborate
Unit Size 500mg 1g 1g 1g 1g 5g 1g 1g
Many hypervalent organoiodanes may decompose violently when exposed to heat, shock, and friction, etc. Sufficient safety measures, such as usage of safety shield, wearing of protective equipment, and extreme caution should be taken, when using this compound, from the opening up to the disposal of the reagents.
References 1) 2) 3) 4)
184
1984, 709. A. Varvoglis, P. J. Stang, V. V. Zhdankin, . 1996, , 1123. 1999, number M. Ochiai, , 2. 2002, H. Togo, K. Sakuratani, , 1018; H. Togo, K. Sakuratani, Kasei Kogyo Co., Ltd., Jpn. Kokai Tokkyo Koho 2003 113131, 2003.
Availability, price or specification of the listed products are subject to change without prior notice.
2002, 1966; Tokyo
Phase-Transfer Catalysts
Phase-Transfer Catalysts A phase-transfer catalyst enables the reaction in a heterogeneous system between general organic compounds soluble in organic solvents and compounds soluble in water such as inorganic salts. The reaction can be accomplished in a biphasic system of an inexpensive nonpolar aprotic solvent and water without using DMSO or DMF which are high-polar solvents. A phase-transfer catalyst is soluble in both solvents, and it carries anions of inorganic salts into organic solvents and returns them into the water phase. Reactions usually progress under mild conditions with easy work-up procedures. For this reason, they are also used industrially. Typical phase-transfer catalysts are quaternary ammonium salts, crown ethers, and phosphonium compounds etc. Reaction examples are shown as follows.1-4) Alkylation CH3OCH2CHCH3 OH
TBAB
+ BuCl
50% NaOH aq.
OBu Y. 97%
TBAB : Tetrabutylammonium Bromide
Bu3P
C8H17Cl
+ Na2S
C16H33
1)
CH3OCH2CHCH3
2)
Br
(C8H17)2S
H2O
Y. 91%
Cyanation 3)
Cl(CH2)3Cl
18-Crown-6
+ KCN
NC(CH2)3CN
CH3CN
Y. 97%
Oxidation CH3(CH2)7CH CH2 + KMnO4
4)
(C8H17)3N CH3 Cl
CH3(CH2)7CO2H
Benzene – H2O
Y. 91%
Quaternary Ammonium Compounds (see p.337) Crown Ethers (see p.275) Phosphonium Compounds (see p.350) Pyridinium Compounds (see p.345) Viologens (see p.248) The asymmetric synthesis is realized using optically-active phase-transfer catalysts. The asymmetric synthesis using the cinchona alkaloid derivative as a phase-transfer catalyst was reported in the 1980s.5) Shibasaki . succeeded in the total synthesis of cylindricine C involving the asymmetric Michael addition catalyzed by tartaric acid derivatives.6) In this section, we introduce the cinchona alkaloid derivatives and the tartaric acid derivatives as the asymmetric phase-transfer catalysts. CH2 OH N
Ph2C N
Cl
N
O Ot-Bu
+
BnBr
O 10 mol% CH2Cl2 50% NaOH aq. 20 ºC, 9 h
Ph2C N
5)
Ot-Bu Bn
Y. 75% 66% e.e. (R)
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
185
Phase-Transfer Catalysts
5
O Ph
N
CO2Bn
O
(S,S)-TaDiAS-2nd* (cat.) 10 mol%
O
+ C6H13
5
Ph
O
Cs2CO3, PhCl -40 ºC, 66 h
Ph
O
N BnO2C
Ph
N
BnO2C
O tandem cyclization
C6H13
Y. 84% 82% e.e.
6)
N C6H13
C6H13
HO
(+)-cylindricine C total 6 steps
B1683
B1689
CH2
CH
H
H
CH2
CH
Cl
Cl HO
H
CH2
Cinchona Alkaloid Derivatives
Chiral Phase-Transfer Catalysts
N
B1684
HO
CH2
H
N
B1685 H
CH2
CH2
CH
CH
Cl N
HO
H Cl
CH2
HO
H
N CH2
H CH3O
CH3O
N
N
Product No. Product Name B1683 B1689 B1684 B1685
Unit Size
N-Benzylcinchonidinium Chloride N-Benzylcinchoninium Chloride N-Benzylquinidinium Chloride N-Benzylquininium Chloride
D3475 CH3 CH2Ph CH2 N CH2 O
Tartaric Acid Derivatives
O CH2 N CH2 CH2Ph CH3
10g 5g 5g 5g
D3476
CH3 CH3 2BF4
2
2
CH3 CH2Ph CH2 N CH2 O O CH2 N CH2 CH2Ph CH3
CH3 CH3
2
2
2BF4
Product No. Product Name D3475 D3476
186
N
N
6,10-Dibenzyl-N,N '-dimethyl-N,N,N ',N '-tetrakis(4-methylbenzyl)-1,4-dioxaspiro[4.5]decane(2R,3R)-diylbis(methylammonium) Tetrafluoroborate [=(R,R)-TaDiAS-2nd] 6,10-Dibenzyl-N,N '-dimethyl-N,N,N ',N '-tetrakis(4-methylbenzyl)-1,4-dioxaspiro[4.5]decane(2S,3S)-diylbis(methylammonium) Tetrafluoroborate [=(S,S)-TaDiAS-2nd]
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 200mg
1g
200mg
1g
Phase-Transfer Catalysts
References H. H. Freedman, R. A. Dubois, . 1975, , 3251. 1974, 565. D. Landini, F. Rolla, F. L. Cook, C. W. Bowers, C. L. Liotta, . 1974, , 3416. C. M. Starks, . 1971, , 195. M. J. O'Donnell, W. D. Bennett, S. Wu, . 1989, , 2353. T. Shibuguchi, H. Mihara, A. Kuramochi, S. Sakuraba, T. Ohshima, M. Shibasaki, . 2006, , 4635; H. 2007, Mihara, T. Shibuguchi, A. Kuramochi, T. Ohshima, M. Shibasaki, , 421. 7) Review: Phase-Transfer Catalysts M. Makosza, . 2000, , 1399; J. M. McIntosh, . 1978, , 235; 1976, 168; A. C. Knipe, P. Varughese, . 1977, , 666; G. W. Gokel, H. D. Durst, . 1976, 1973, 441. , 618; J. Dockx, 2003, Asymmertic Phase-Transfer Catalysts K. Nagasawa, , 670; K. Maruoka, T. Ooi, . 2003, , 3013.
1) 2) 3) 4) 5) 6)
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
187
Combinatorial Chemistry
Combinatorial Chemistry Combinatorial chemistry is a technique in which a number of compounds are simultaneously synthesized and has received much focus in the development of drugs. Of the array of products produced, which are called“libraries”, those with the desired functions and activity, are easily identified and isolated. Solid-phase syntheses are widely used. In the solid-phase syntheses, the desired compounds are held by covalent bond to the solid-phase. Therefore, the excess reaction reagents can easily be removed by washing. A variety of compounds can be synthesized quickly upon determination of their synthetic routes. Furthermore, they have the advantage of being capable of automatic synthesis. Currently, the reactions which can be utilized in the solid-phase syntheses are limited, however, other potentially utilizable reactions are vigorously being explored. In the other synthesis of libraries, the liquid-phase reactions are carried out utilizing conventional organic synthetic reactions. Some developments have been reported and future developments are being anticipated. We have put on the market various kinds of resins which have widely been utilized through the solidphase synthetic technique and useful diphenylphosphino polystyrene resin for liquid-phase Mitsunobu reaction. Any of these resins are easy to use in meshes, swelling volume and functional content. For the polymer-supported reagent used for liquid-phase synthesis, please refer to “Polymer-Supported Reagents” (p.24), and for a group of building blocks intended for the preparation of the combinatorial libraries, please refer to our website. We provide the structure search on the website. A2006
B2172
A2047 A1543 CH2NH2
CH2NHCH2CH2NH
Resins
B2372
P
P
P
B2370
P
CH2O
C NH(CH2)4NHO2S
P
CH2O
C1747 C1751 C1746 C1750 C1744 C1643 C1642 C1745
C NH(CH2)2NHO2S
O 2N
O 2N
C1679
B2371
Br
CH2Cl P
P1432 P1379
H0987 H0986 Cl
P
CH2O
P
C NH(CH2)3NHO2S
C Cl
P
CH2O
CH2OH
P
O 2N
S0545
T1889
SO2Cl P
P
C Cl
Product No. Product Name A2006
N-(2-Aminoethyl)aminomethyl Polystyrene Resin cross-linked with 1% DVB (50-100mesh)
A2047 A1543 B2172
Aminomethyl Polystyrene Resin cross-linked with 1% DVB (200-400mesh) (2.4-3.0mmol/g) Aminomethyl Polystyrene Resin cross-linked with 1% DVB (200-400mesh) (0.5-0.7mmol/g) 4-Bromo Polystyrene Resin cross-linked with 2% DVB (200-400mesh) (2.6-2.8mmol/g)
(3.1-3.5mmol/g)
188
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 5g 5g 5g 5g
25g 25g 25g 25g
Combinatorial Chemistry
Product No. Product Name
Unit Size
B2372
N-(4-Benzyloxytrityl)-N '-(2-nitrobenzenesulfonyl)-1,4-diaminobutane Resin
B2370
N-(4-Benzyloxytrityl)-N '-(2-nitrobenzenesulfonyl)-1,2-diaminoethane Resin
1g
cross-linked with 1% DVB (200-400mesh) (0.9-1.1mmol/g) cross-linked with 1% DVB (200-400mesh) (0.9-1.1mmol/g) Chloromethyl Polystyrene Resin cross-linked with 2% DVB Chloromethyl Polystyrene Resin cross-linked with 2% DVB Chloromethyl Polystyrene Resin cross-linked with 2% DVB Chloromethyl Polystyrene Resin cross-linked with 1% DVB Chloromethyl Polystyrene Resin cross-linked with 1% DVB Chloromethyl Polystyrene Resin cross-linked with 1% DVB Chloromethyl Polystyrene Resin cross-linked with 1% DVB Chloromethyl Polystyrene Resin cross-linked with 2% DVB
C1747 C1751 C1746 C1750 C1744 C1643 C1642 C1745 B2371
(100-200mesh) (100-200mesh) (200-400mesh) (100-200mesh) (100-200mesh) (200-400mesh) (200-400mesh) (200-400mesh)
5g 5g 5g 5g 5g 5g 5g
(2.0-2.5mmol/g) (0.8-1.2mmol/g) (0.8-1.2mmol/g) (2.0-2.5mmol/g) (0.8-1.2mmol/g) (1.6-1.8mmol/g) (0.8-1.3mmol/g) (2.0-2.7mmol/g)
1g 25g 25g 25g 25g 25g 25g 25g 5g
N-(4-Benzyloxytrityl)-N '-(2-nitrobenzenesulfonyl)-1,3-diaminopropane Resin
1g 5g
cross-linked with 1% DVB (200-400mesh) (0.9-1.1mmol/g)
C1679 H0987
2-Chlorotrityl Chloride Resin cross-linked with 1% DVB (200-400mesh) (1.0-1.8mmol/g) 4-(Hydroxymethyl)phenoxymethyl Polystyrene Resin cross-linked with 1% DVB (200-400mesh)
H0986
4-(Hydroxymethyl)phenoxymethyl Polystyrene Resin cross-linked with 1% DVB (200-400mesh)
P1432 P1379 S0545 T1889
Polystyrene Resin cross-linked with 1% DVB (100-200mesh) Polystyrene Resin cross-linked with 1% DVB (200-400mesh) Sulfonyl Chloride Polystyrene Resin cross-linked with 1% DVB (50-100mesh) (4.5-4.8mmol/g) Trityl Chloride Resin cross-linked with 1% DVB (200-400mesh) (1.0-1.8mmol/g)
(1.0-2.0mmol/g) (0.5-1.0mmol/g)
B2322
D2707
CH3O
CH3 CH3 Si
H0961
C
OH
OCH3
CH2OH
H1269 O
O C OCH3
OCH2
5g
C CH3
CH3 CH3
H1049
25g 100g 25g 25g 5g
C OH
O
NO2
CH2O
5g 25g
O
C OH
Linkers
25g
H0769
O OCH2
5g
OCH2 C OH
O
NO2 O CH2OH
OH
CH2OH
Product No. Product Name B2322 D2707 H0769 H1049 H0961 H1269
2-[4-(tert-Butyldimethylsilyloxymethyl)-2-nitrophenoxy]acetic Acid 2,4-Dimethoxy-4'-hydroxybenzophenone 4-Hydroxymethylbenzoic Acid 2-[4-(Hydroxymethyl)-2-nitrophenoxy]acetic Acid Methyl Ester 4-(Hydroxymethyl)phenoxyacetic Acid 3-Hydroxyxanthen-9-one
Unit Size 100mg 5g 10g 100mg 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
1g 25g 25g 1g 1g 5g
189
Combinatorial Chemistry
●TNBS & Chloranil Test Kit To conduct the solid phase synthesis, as simple methods TNBS and Chloranil Test are used to detect free amino group on the resin after reaction. Using TNBS Test, the primary amino group can be detected, while Chloranil Test can detect the presence of both primary and secondary amino groups. This method is much safe and simple detection method of free amino group compared to Kaiser Test which requires toxic substance, potassium cyanide fall under the Poisonous and Deleterious Substances Control Law in Japan. Product No. Product Name T2024
Picrylsulfonic Acid (ca. 1% in DMF) N,N-Diisopropylethylamine (ca. 10% in DMF) [for Detection of Primary Amines]
190
Unit Size
TNBS Test Kit 10ml×1 10ml×1
C1771
Chloranil Test Kit
P1447 D2937 C1770 A1640
Chloranil (ca. 2% in DMF) 10ml×1 Acetaldehyde (ca. 2% in DMF) 10ml×1 [for Detection of Primary and Secondary Amines] Picrylsulfonic Acid (ca. 1% in N,N-Dimethylformamide) N,N-Diisopropylethylamine (ca. 10% in N,N-Dimethylformamide) Chloranil (ca. 2% in N,N-Dimethylformamide) Acetaldehyde (ca. 2% in N,N-Dimethylformamide)
Availability, price or specification of the listed products are subject to change without prior notice.
1kit
1kit 10ml 10ml 10ml 10ml
Gas Cylinders
Gas Cylinders Our company is endeavoring to help you in your research by charging small-sized gas cylinders with gaseous reagents for easy dispensing. 【Characteristics】 • The flow of gas can be adjusted across a wide range. • Convenient for moving since gas cylinders are small sized (7 × 14 cm) and lightweight (under 500g). • Metallic pressure-tight container (14 kg/cm2). 【Storage Method】 Store in a cool place before opening and use the compressed reagent as soon as possible.* One-time, exhaustive use is recommended. If the reagents need to be stored, please keep the following in mind with the utmost caution. *The valve packing may swell in storage and gas might not flow out. 1. The charge intake cover should be attached after insuring that the gas flow has ceased. 2. Select a low-temperature, well-ventilated place for storage. 3. Reagents that require refrigeration should be stored only in an explosion-proof refrigerator. Potential risks for explosion through ignition of a small gas leak from the spark of the thermostat may be present in ordinary refrigerators. B0748 1-Butyne can decompose explosively so these reagent cylinders should not be stored for re-use. 【Notes】 • These reagents are pressurized. Sufficient care should be taken in handling them, in addition to wearing appropriate protective equipment. • Take care to insure that the inner pressure of reaction apparatus does not exceed the inner pressure of the gas cylinders. As an extra precaution, we recommend that a check valve be attached within the gas introduction path. • Empty the contents thoroughly before disposing of the gas cylinder.
Hydrocarbons Product No. Product Name
bp(℃ )
B0675 B0677 B0689 B0690 B0691 B0692 B0748 I0090 I0091 M0177
-4.5 -0.5 -6.0 3.7 0.8 1.0 8.1 -11.6 -7.0 20.1
1,3-Butadiene (stabilized with TBC) Butane 1-Butene cis-2-Butene trans-2-Butene 2-Butene (cis- and trans- mixture) 1-Butyne Isobutane Isobutene 3-Methyl-1-butene
Unit Size 100g 100g 100g 100g 100g 100g 100g 100g 100g 100g
Ethers Product No. Product Name
bp(℃ )
M0110 M0224
10.8 -24.8
Ethyl Methyl Ether Methyl Ether
Unit Size 100g 100g
Amines Product No. Product Name E0245
Ethylamine Anhydrous
bp(℃ )
Unit Size
16.6
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
100g
191
Gas Cylinders
Halides Product No. Product Name
bp(℃ )
B1618 C0164 C1397 D0356 D0366 D0417 D2384 F0042 O0204 T1476 V0032
4.5 12.3 -9.5 -29.5 31.7 4.1 27.7 23.7 -6.0 -26.2 16.0
Bromomethane Chloroethane 1-Chloro-1,1-difluoroethane Dichlorodifluoromethane 1,1-Dichloroethylene (stabilized with MEHQ) 1,2-Dichloro-1,1,2,2-tetrafluoroethane 2,2-Dichloro-1,1,1-trifluoroethane Trichlorofluoromethane Octafluorocyclobutane 1,1,1,2-Tetrafluoroethane Vinyl Bromide (stabilized with MEHQ)
Unit Size 50g 200g 100g 400g 250g 100g 300g 400g 100g 100g 100g
To use these products charged in cylinder, 1) Charge valve & 2) Connectors which are sold separately are required. (Connectors are used for connection between the reaction apparatus and gas cylinders) 1) Charge valve 【Method of Use】(The actual form may differ slightly from the illustration.) 1. Before mounting the charge valve, turn the handle (A) to the left and pull the needle (B) upward as far as it can go. 2. Mount the charge valve on to the gas cylinder. 3. After the charge valve is mounted, tighten the disk (C) attached at the bottom of the charge valve. Be careful not to over tighten. 4. Turning the handle (A) to the right makes the needle (B) come down and perforate the sealing lid. 5. On turning the handle (A) to the left, the valve opens to allow the gas to flow. 6. To stop the gas flow, turn the handle (A) to the right. Do not remove the charge valve until the cylinder is empty and the inside pressure becomes equal to atmospheric pressure. 2) Connectors 【Method of Use】 1. Detach the charge intake cover from the charge valve. 2. Set the cap nut in the connector. Then, mount them in the charge intake. 3. Confirm that the connected side of the connector and the charge intake are normal. Afterwards, tighten the cap nut with the spanner etc. Be careful not to over tighten. 4. Use a commercially available tube fitting suitable for the outside diameter of the pipe connector when connecting to the gas introduction pipe of the reactor. We have two types of connectors, a tube connector for under ordinary pressure and a pipe connector for under increased pressure. The outside diameter of both connectors is 6.0 mm. Each connector is bundled with a cap nut. Please use both connectors according to the situation. Tube Connector (for under ordinary pressure)
Pipe Connector (for under increased pressure)
Tube Connector Cap Nut
Pipe Connector Cap Nut
Product No. Product Name V0030 V0070 V0071
192
Valve (for Gas cylinder) Tube Connector (for Gas cylinder) Pipe Connector (for Gas cylinder)
Availability, price or specification of the listed products are subject to change without prior notice.
Precursors
Precursors for Preparation of Highly Reactive Reagents The highly reactive reagents are generally unstable and frequently arrive to the customer in a decomposed state. Consequently, these compounds should be prepared immediately prior to use. The precursors required for such preparations are shown below. For details, please refer to references. Cyanamide Cyclopentadiene Diazomethane Dimethyl Ketene Ethyl Diazoacetate Hydrogen Bromide
●Preparation of Cyanamide1) Product No. Product Name
C0006
Unit Size
Calcium Cyanamide CaNCN
25g
500g
NH2CN + Ca(O2CCH3)2
+ 2CH3CO2H
Glacial acetic acid 57g (54mL, 0.75mol) and water 135mL are placed in a large sized agate mortar and while thoroughly stirring, calcium cyanamide 40g (0.5mol) is slowly added and the mixture is grounded. Acetylene gas is generated, yielding a dull grayish to dark colored paste. Subsequently, the paste is dried at 40∼50ºC for 12∼18 hours under reduced pressure 30mmHg to yield a gray powder which is placed in a Soxhlet extractor. The powder is extracted with 400mL of ether containing several drops of dilute acetic acid for 2∼3 hours (2×). The ether extraction is dried over anhydrous sodium sulfate (30g). Concentration under a reduced pressure gives 10.5∼15.8g (50∼70% from CaCN2) colorless viscous oil.
●Preparation of Cyclopentadiene2) Product No. Product Name
D0443
Unit Size
Dicyclopentadiene (stabilized with BHT)
25ml Δ
500ml
2
The reaction apparatus (Figure 1) is assembled by attaching a thermometer, Vigreaux distilling column and Liebig condenser to a 500mL two necked flask. The receiver is cooled by means of a refrigerants or freezing mixtures. Dicyclopentadiene (195g) is placed in the two necked flask and heated to about 160ºC with an electric heating mantle or oil bath. Thermal decomposition begins at about 150ºC and distillates at 43∼46ºC can be obtained (addition of iron powder expedites the thermal decomposition rate of cyclopentadiene). Heating is applied slowly, because rapid temperature increases cause dicyclopentadiene to distill prior to undergoing thermal decomposition. In such a case, re-distillation allows narrow boiling-point distillates. Cyclopentadiene dimerzes rapidly at room temperature and should be used immediately.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
193
Precursors
Figure 1. Reaction apparatus
●Preparation of Diazomethane3) Product No. Product Name
Unit Size
N-Methyl-N-nitroso-p-toluenesulfonamide
T0323
NO CH3
SO2N CH3
+
ROH
KOH
CH2N2
25g
+
CH3
SO2OR
+
500g
H2O
A reaction and distillation apparatus is assembled by connecting an addition funnel and condenser to a 100mL long-neck distillation flask. Two in series receiving flasks are connected to the apparatus with the second flask containing an induction tube. A solution containing 6g potassium hydroxide in 10mL water, and a solution containing 35mL carbitol (diethylene glycol monoethyl ether) and 10mL of ether are placed in the distillation flask. 20∼30mL ether is placed in the second receiving flask making sure the induction tube is immersed into the ether. Both receiving flasks are cooled to 0ºC. A solution containing -methyl-nitroso- -toluenesulfonamide (21.5g, 0.1mol) in 140mL ether is placed in the addition funnel. Heat the distillation flask to 70ºC in a warm water bath. As the ether begins to boil, start adding the -methyl- nitros- -toluenesulfonamide solution dropwise over a 20 minute period. Swirl distillation flask from time to time. About 3g of diazomethane (0.07mol) is dissolved in ether distillate. The reagent should be used at once without storing it. *Note: Diazomethane is explosive and highly toxic. Wear protective gloves, protective goggles, protective mask and work in a well ventilated fume hood. Also place a safety shield in front of distillation apparatus. Diazomethane may explode upon contact with ground glass joints or other scratched glass surfaces, so avoid handling or preparing this compound with such surfaces. Ordinarily, diazomethane is used as a solution in ether. *We have TMS diazomethane available. This reagent is analogous in reactivity to diazomethane, but less explosive and less toxic. Please consider using this reagent prior to preparing diazomethane. Product No. Product Name
T1146 194
Trimethylsilyldiazomethane (ca. 10% in Hexane, ca. 0.6mol/L)
Unit Size
10ml 25ml 100ml
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Precursors ●Preparation of Dimethyl Ketene44) Product No. Product Name
Unit Size
Tetramethyl-1,3-cyclobutanedione
D0258
25g
O Δ
(CH3)2C
(CH3)2C C O
C(CH3)2 O
Tetramethyl-1,3-cyclobutanedione is placed in the ketene generation apparatus, heated at 120ºC, and sublimed, then thermally decomposed by means of the red heated nichrome wire under the nitrogen atmosphere. Subsequently, the evolved gas is captured by means of a trap cooled in dry ice-acetone to obtain dimethylketene in about 60% yield. Dimethylketene is a yellowish liquid (bp 34ºC) with characteristic odor, remarkable reactivity, and transforms into a solid dimer when allowed to stand at room temperature. On exposure to air it generates white solid peroxides and explodes with even the slightest stimulus. For this reason, its monomer is stored under nitrogen at -78ºC and it is used immediately.
●Preparation of Ethyl Diazoacetate5) Product No. Product Name
Unit Size
Glycine Ethyl Ester Hydrochloride
G0102
H2NCH2CO2C2H5
. HCl
+
25g
NaNO2
N2CHCO2C2H5
+
NaCl
+
500g
2H2O
A solution containing 140g glycine ethyl ester hydrochloride (1mol) in 250mL water is placed in a 2L four neck flask. 600mL dichloromethane is added and the mixture is cooled to -5ºC under a nitrogen atmosphere. A solution containing 83g sodium nitrite in 250mL water is cooled to 0ºC and added with stirring to the reaction mixture. While keeping the reaction temperature below -9ºC, 95g 5% sulfuric acid is added dropwise to the reaction over a 3 minute period. After ten minutes addition stirring the reaction is transferred to a 2L separatory funnel while cold. The isolated yellow-greenish organic phase is poured into a cooled 1L 5% sodium carbonate solution, then placed into a separatory funnel and shaken. The isolated aqueous phase is extracted with 75mL dicholoromethane, dried over 15g anhydrous sodium sulfate, and concentrated under reduced pressure (350mmHg). Further concentration at 20mmHg and a bath temperature of 35ºC gives 90∼100g (79∼88%) yellow oily substance. The product is pure enough to be used for ordinary synthesizing purposes. It is explosive, and distillation under even reduced pressure is hazardous. *Ethyl diazoacetate is explosive and very toxic. Wear protective gloves, protective goggles, protective mask, and use a safety screen. Work in a well ventilated fume hood.
●Preparation of Anhydrous Hydrogen Bromide6) Product No. Product Name
Unit Size
1,2,3,4-Tetrahydronaphthalene
T0107
25ml
500ml
Br Br
+
4Br2
+
4HBr
Br Br
Bromine is slowly added dropwise to a round bottom flask containing a suspension of iron and 1,2,3,4tetrahydronaphthalene. In the early stage of the reaction, the flask is cooled with water. The reaction is warmed to 30 to 40ºC allowing gas evolution. The gas is passed through a wash bottle containing 1,2,3,4-tetrahydronaphthalene in order to eliminate any bromine in the hydrogen bromide. For optimum yields of hydrogen bromide, dry the 1,2,3,4tetrahydronaphthalene over anhydrous sodium sulfate and then distill it under a dry inert atmosphere (such as argon or nitrogen). If any moisture is introduced into the reaction, the yield of hydrogen bromide becomes remarkably poor. References 1) 2) a) b) 3) a) b)
. 1963, Coll. Vol. , . 1963, Coll. Vol. . 1962, , 50. . 1963, Coll. Vol. . 1973, Coll. Vol.
645. , 238;
4) 5) 6)
1963, , 467. . 1963, Coll. Vol. , 424. . 1939, , 149.
, 250; , 351.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
195
C60 & C70
C60 & C70 The Third Form of Carbon Fullerene C60 and C70 which are the third allotropes of carbon, subsequent to diamond and graphite, have a beautiful spherical structure as shown in the figure. The form of Fullerene C60 resembles the dome built by the architect, Buckminster Fuller, and therefore, it is called“Buckminsterfullerene”. The existence of Buckminsterfullerenes was hypothesized by Osawa1) more than 40 years ago and discovered by Smalley and co-workers2) relatively recently. Afterwards, Huffman, Kratschmer and coworkers3) have reported on the method to generate Fullerenes in a considerably large quantity. Fullerenes have been studied intensively, particularly in the fields of superconducting devices4), ferromagnets5), nonlinear optical materials6) , pharmaceuticals7) and the like. Moreover, solvent-soluble fullerene derivatives obtained by chemical modification8) , such as [60]PCBM9) or C60MC1210) , have been developed and applied in various fields including organic semiconducting or solar cell materials.
CH3 OCH3
(CH2)11CH3
N
O
C60
C70
Product No. Product Name B1641 B1660 B1642 B1694 M2088 C2415
Fullerene C60 (pure) Fullerene C60 Fullerene Extract, C60 (contains ca. 20% C70) Fullerene C70 Methyl [6.6]-Phenyl-C61-butyrate C60MC12
[60]PCBM
C60MC12
Unit Size 100mg 100mg 100mg
1g 1g 1g 100mg 100mg 100mg
Please note that B1642 is a mixture of C60 and C70 in an about 8 to 2 ratio containing a trace amount of other higher Fullerene.
References 1) 2) 3) 4)
5) 6)
7)
8)
9) 10) 11)
196
1970, E. Osawa, , 854. 1985, H. W. Kroto, J. R. Heath, S. C. O'Brein, R. F. Curl, R. E. Smalley, , 162. 1990, W. Kraetschmer, L. D. Lamb, K. Fostiropoulos, D. R. Huffman, , 354. A. F. Hebard, M. J. Rosseinsky, R. C. Haddon, D. W. Murphy, S. H. Glarum, T. T. M. Palstra, A. P. Ramirez, A. R. Kortan, 1991, 1991, , 600; K. Tanigaki, T. W. Ebbesen, S. Saito, J. Mizuki, J. S. Tsai, Y. Kubo, S. Kuroshima, , 222; S. Margadonna, K. Prassides, . 2002, , 639. 1991, P. M. Allemand, K. C. Khemani, A. Koch, F. Wudl, K. Holczer, S. Donovan, G. Gruner, J. D. Thompson, , 301; L. A. Zheng, E. V. Barrera, R. D. Shull, . 2002, , 523. Q. Gong, Y. Sun, Z. Xia, Y. H. Zou, Z. Gu, X, Zhou, D. Qiang, . 1992, , 3025; L. W. Tutt, A. Kost, 1992, , 225; R. A. Ganeev, A. I. Ryasnyansky, V. I. Redkorechev, K. Fostiropoulos, G. Priebe, T. Usmanov, . 2003, , 131. 1997, Y. Tabata, Y. Ikada, , 30; N. Miyata, Y. Yamakoshi, I. Nakanishi, 2000, , 1007; Y. Yamakoshi, N. Umezawa, A. Ryu, K. Arakane, N. Miyata, Y. Goda, T. Masumizu, T. Nagano, 2003, , 12803. 1992, H. Schwarz, , 293; A. Koch, H. Eckert, G. Srdanov, H. M. Webb, in Ser. 481, ed. by G. S. Hammond, V. J. Kuck, ACS, Washington D. C., 1992. S. Günes, H. Neugebauer, N. S. Sariciftci, . 2007, , 1324. 2010, , Y. Horii, K. Sakaguchi, M. Chikamatsu, R. Azumi, K. Yase, M. Kitagawa, H. Konishi, 101601. 1991, Review: H. W. Kroto, A. W. Allaf, S. P. Balm, . 1991, , 1213; ; R. E. Smalley, . 1992, , 98; M. S. Dresselhaus, . 1995, , 487; M. Iyoda, M. Yoshida, 1995, , 756; N. F. Goldshleger, . 2001, , 255. The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Carbon Nanotube
Carbon Nanotube
Carbon Nanotubes (CNT), which were discovered by Iijima in 1991, are composed entirely of carbon atoms, as is C60.1) As the name implies, this carbon structure is shaped like a tube on a nanometer scale. In 1991, Hufman and Kraetschmer reported a procedure for the preparation of C60 by an arc discharge. Many researchers had used this technique to obtain C60 from the soot which had collected on the anode. However, Iijima focused his attention on the soot which had accumulated on the cathode carbon rod. In this soot, Iijima found a needle like substance which he characterized as CNT. These early nanotubes were multi-walled carbon nanotubes (MWCNT), composed of many layers. Two years later, single-walled carbon nanotubes (SWCNT) were discovered. In 1996, Smalleys developed a mass production method of SWCNT2) and since then, research of CNT has progressed rapidly. Today, researchers are making advances in the applications of CNT as probes for Scanning Probe Microscopy, nano-tweezers,3) field-emitter of Field Emission Display (FED),4) nanoelectronics devices,5) hydrogen fuel cells,6) thin films,7) and organic solar cells.8) Moreover, CNT generally tend to form bundles due to their van der Waals interactions, which makes them insoluble in organic solvents. In response to that, solvent-soluble CNT obtained by chemical modification have been developed and applied in many fields.9) Product No. Product Name
Unit Size
C2142 C2143 C2149 C2148 C2150 C2153 C2152 C2155 C2154 C2157 C2156 C2159 C2158 C2151 C2147
Carbon Nanotube Single-walled (>55%) below 2nm(diam.), 5-15μm(length) Carbon Nanotube Double-walled (>50%) below 5nm(diam.), 5-15μm(length) Carbon Nanotube Multi-walled below 10nm(diam.), 1-2μm(length) Carbon Nanotube Multi-walled below 10nm(diam.), 5-15μm(length) Carbon Nanotube Multi-walled 10-20nm(diam.), 5-15μm(length) Carbon Nanotube Multi-walled 10-30nm(diam.), 1-2μm(length) Carbon Nanotube Multi-walled 10-30nm(diam.), 5-15μm(length) Carbon Nanotube Multi-walled 20-40nm(diam.), 1-2μm(length) Carbon Nanotube Multi-walled 20-40nm(diam.), 5-15μm(length) Carbon Nanotube Multi-walled 40-60nm(diam.), 1-2μm(length) Carbon Nanotube Multi-walled 40-60nm(diam.), 5-15μm(length) Carbon Nanotube Multi-walled 60-100nm(diam.), 1-2μm(length) Carbon Nanotube Multi-walled 60-100nm(diam.), 5-15μm(length) Carbon Nanotube Aligned Multi-walled 10-20nm(diam.), 5-15μm(length) Carbon Nanotube Bundled Multi-walled below 10nm(diam.), 5-15μm(length)
200mg 200mg
(allowable temperature limit : 620℃ )
200mg
C2146
Carbon Nanotube Herringbone 10-20nm(diam.), 5-15μm(length)
1g 1g 1g 1g 1g 1g
1g 1g 1g 5g 5g 1g 5g 1g 5g 1g 5g 1g 5g 1g 1g 200mg
C60 & C70 (see p.196)
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
197
Carbon Nanotube
References 1) 2) 3) 4) 5) 6) 7) 8) 9)
198
1991, S. Iijima, , 56. 1996, R. E. Smalley, , 483. H. Nishijima, . 1999, , 4061; S. Akita . 2001, , 1691. Q. H. Wang, . 1997, , 3308; Y. Nakayama, . 2001, , 207. 1998, 1997, S. J. Tans, , 49; S. J. Tans, , 474 ; M. Suzuki, 2002, 2001, , 2273; A. Bachtold, , 1317. 1997, A.C. Dillon, , 377. Review: L. Hu, D. S. Hecht, G. Grüner, . 2010, , 5790. T. Umeyama, M. Fujita, N. Tezuka, N. Kadota, Y. Matano, K. Yoshida, S. Isoda, H. Imahori, 11484. Review: D. Tasis, N. Tagmatarchis, A. Bianco, M. Prato, . 2006, , 1105.
.
2007,
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
,
Building Blocks for Dendrimers
Building Blocks for Dendrimers Dendrimers are a single dendritic polymer consisting of three layers, its core, dendron regularly branched from the core, and the exterior surface layer. The typical species become globular and their size is in a clear-cut nm scale, having physical properties different from conventional straight polymer. Since their report in 1984 by Tomalia and co-workers, dendrimers have received much attention in many areas.1) Nowadays, applications of dendrimers are examined in chemical sensors, catalysts, electronics, photonics and medicines.2, 3) Functional elements and functional groups can be introduced into the core, dendron and surface layer. The synthetic technique is divided mainly into the divergent method, where synthesis proceeds from the center core toward the outside, and the convergent method, where synthesis proceeds from the exterior shell to the core. For the synthesis of the regularly branched portions, multifunctional compounds have been utilized. The 1,3,5-trisubstituted benzenes, shown below are useful building blocks for dendrimers. Please refer to our website for other building blocks. We provide the structure search on the website and you can search by the substructure.
B2081
B2118
B2248 CH2Br
BnO
COOH
O
BnO
O
O
NH2
OCH3 CH3O
CH3O
B2246
B2247
B2866
CH2OH
CH2OH
CH2O
CH2O
R OCH2
H 3C tBu
CH2O
R R=
O C OCH3
R
Ph
tBu
Si O
CH3O
CH2OH
CH3O
O Si Ph
Ph
B2120 COOH
D2085
O
NO2
OBn
D2832
BnO
CHO
Br
Br
AcO
OBn
D2824
Br
OAc
D2651
BnO
Br OH
AcO
BnO
CH2Br
OBn
OBn
BnO
I0302 TMS
Br
OAc
B2093
D2724
Br
COOH
CH2OH
COCH3
COOH
Br
OCH3
COOH
D2353
D2844 COCH3
D2267
OBn
Si O CH2OH
D1978
CH3O
CHO
COCH3
H3C C H3C
CH2O
Cl
D3184
BnO
CH2Br
CH3O
CH3O
C1258
O
CH3O
CH2O
Ph CH3O
O2N
OCH3
CH3O
CH3O
OH
OCH3
O
CH2O
B2052
R
O O
BnO
B2865
O
O
CH3O
CH2Br
BnO
H2N
OCH3
OCH3
CH2O
NCO
Br
Cl
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
Cl
199
Building Blocks for Dendrimers
D1981
D2875 CONH2
COCH3
HO
OH
HO
D1164
OH
D1558
OCH3
CH3O
HO
D2657
CH3O
OCH3
D2950
NH2
OCH3
CH3O
H0794
CH3O
OH
D2609 COOH
CH2COOH
CH2Br
HO
OH
D1534
D1484 CH2OH
COOH
CONH2
CHO
D2656
D0570 D2554
D2594 CH2OH
COCl
CH3O
CH3O
OCH3
M1413
OCH3
B2051 COOCH3
OH
COOH
OCH3
tBu
OCH3
CH3O
B2092
CH3O
OCH3
M1929
OBn
Br
COOH
D2215
Br
CH3O
HO
OH
D1737
OH
CH3O
tBu
Si O
O Si Ph
Ph
Ph
D2655 COOCH3
COOCH3
COOCH3
COOCH3
BnO
HO
Ph
OCH3
COOCH2CCl3
HO
OH
T2647 COOH
HOOC
COOH
Product No. Product Name B2081 B2118 B2248 B2865 B2052 B2246 B2247 B2866 B2120 C1258 D1978 D2844 D2085 D3184 D2267 D2651 B2093 D2832 D2353 D2824 D2724 I0302 D1981 D2875
200
3,5-Bis(4-aminophenoxy)benzoic Acid 3,5-Bis[3,5-bis(benzyloxy)benzyloxy]benzyl Bromide 3,5-Bis[3,5-bis(3,5-dimethoxybenzyloxy)benzyloxy]benzyl Bromide 3,5-Bis[3,5-bis(methoxycarbonyl)phenoxymethyl]phenol 3,5-Bis(tert-butyldiphenylsilyloxy)benzyl Alcohol 3,5-Bis(3,5-dimethoxybenzyloxy)benzyl Alcohol 3,5-Bis(3,5-dimethoxybenzyloxy)benzyl Bromide 5-(tert-Butyldiphenylsilyloxy)-1,3-benzenedimethanol 3,5-Bis(4-nitrophenoxy)benzoic Acid 1-Chloro-3,5-dimethoxybenzene 3',5'-Diacetoxyacetophenone 3,5-Diacetoxybenzoic Acid 3',5'-Dibenzyloxyacetophenone 3,5-Dibenzyloxybenzaldehyde 3,5-Dibenzyloxybenzoic Acid 3,5-Dibenzyloxybenzyl Alcohol 3,5-Dibenzyloxybenzyl Bromide 3,5-Dibromobenzaldehyde 3,5-Dibromobenzoic Acid 3',5'-Dibromo-4'-hydroxyacetophenone 3,5-Dibromo-1-trimethylsilylbenzene 3,5-Dichlorophenyl Isocyanate 3',5'-Dihydroxyacetophenone 3,5-Dihydroxybenzamide
Unit Size 1g 1g
1g 1g 1g 10g 10g 1g 1g 5g 5g 5g 5g 5g 5g 10g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
5g 5g 1g 200mg 1g 5g 5g 5g 5g 25g 25g 5g 10g 5g 25g 25g 25g 25g 10g 25g 25g 10g 25g 5g
Building Blocks for Dendrimers
Product No. Product Name D0570 D2554 D2656 D1484 D1164 D1558 D1534 D2609 D2594 D2657 D2950 H0794 M1413 B2051 B2092 M1929 D2215 D1737 D2655 T2647
3,5-Dihydroxybenzoic Acid 3,5-Dihydroxybenzoic Acid 3,5-Dihydroxybenzyl Alcohol 3,5-Dimethoxyaniline 3,5-Dimethoxybenzaldehyde 3,5-Dimethoxybenzamide 3,5-Dimethoxybenzoic Acid 3,5-Dimethoxybenzoyl Chloride 3,5-Dimethoxybenzyl Alcohol 3,5-Dimethoxybenzyl Bromide 3,5-Dimethoxyphenylacetic Acid 5-Hydroxyisophthalic Acid 5-Methoxyresorcinol Methyl 3,5-Bis(tert-butyldiphenylsilyloxy)benzoate (ca. 20% in Toluene, ca. 0.28mol/L) Methyl 3,5-Dibenzyloxybenzoate Methyl 3,5-Dibromobenzoate Methyl 3,5-Dihydroxybenzoate Methyl 3,5-Dimethoxybenzoate 2,2,2-Trichloroethyl 3,5-Dihydroxybenzoate (ca. 20% in Dichloromethane, ca. 1mol/L) 1,3,5-Tris(4-carboxyphenyl)benzene
Unit Size 25g 25g 5g 5g 5g 25g 5g 5g 5g 1g 25g
5g 5g 25g 5g 1g
500g 500g 25g 25g 25g 5g 500g 25g 25g 25g 5g 500g 1g 25g 25g 25g 250g 25g 25g 5g
References 1) D. A. Tomalia, J. R. Dewald, M. R. Hall, S. J. Martin, P. B. Smith, Preprints of the 1st SPSJ International Polymer Conference, Society of Polymer Science Japan, Kyoto, 1984, p 65; D. A. Tomalia, J. M. J. Fréchet, 2002, , 2719. 2) F. Vögtle, G. Richardt, N. Werner, in , Wiley-VCH, Weinheim, 2009. 2010, 3) D. Astruc, E. Boisselier, C. Ornelas, , 1857.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
201
Organic Semiconducting Materials
Organic Semiconducting Materials S S
1 P0030
2 P1893
3 D3526
Pentacene (1) is a polyaromatic hydrocarbon consisting of five linearly condensed benzene rings. 1 has attracted much attention as an electronic devices materials in recent years, especially, in the field of p-type semiconductor research.1) Correspondingly, C60 is known as an n-type semiconductor, and both of it and 1 have been actively studied as a transistor consisting only of organic and molecular substance. 1 for use in such applications must be of extremely high purity. TCI offers 1 purified to a suitable standard by recrystallization and sublimation. On the other hand, picene (2), whose benzene rings are condensed in a w-shape, is a stable aromatic hydrocarbon compound. In this form, all five benzene rings can be described by the Kekulé structure.2) Kubozono have reported an efficiency modification of Field-effect transistors (FETs) with 2. Applying 2 into the active layer of FETs resulted in the field-effect mobility value (μ value) being measured 1.1 cm2/Vs. Furthermore, the μ value is improved up to 1.75 cm2/Vs after exposure to O2 atmosphere for 70 hours. This result showed that the modified FET is an O2-assisted devise, as well as having stability against O2.3) In addition, Kubozono have also reported the superconductivity of picene which was intercalated with alkaline metals, such as potassium and rubidium.4) Additionally, Takimiya have developed 2,7-diphenyl[1]benzothieno[3,2- ][1]benzothiophene (3) which includes chalcogen atoms in a molecule. They prepared thin film devices using 3 on silicon substrates by vacuum deposition, and measured their semiconducting properties (Fig.1). According to their results, the field-effect mobility of the device is very high (0.19-2.0 cm2/Vs), and indicates a high value comparable as pentacene (0.5-3.0 cm2/Vs). Moreover, the on-off current ratios were as high as 107, and the semiconducting properties were maintained for over 100 days.5)
Tsub / oC bare SiO2
HMDS
OTS
a
µFET a / cm2 V-1 s-1
Ion / Ioff
rt 60 100 rt 60 100
0.19-0.22 0.21-0.26 0.12-0.15
5 × 106 5 × 106 5 × 106
0.42-0.45 0.51-0.53 0.93-1.2
106 5 × 106 107
rt 60 100
0.36-0.46 0.43-0.58 1.0-2.0
5 × 106 107 >107
data from more than 20 devices.
Fig.1 It is expected that these types of organic semiconducting materials will significantly advance the field of electronic devices applied research.
202
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Organic Semiconducting Materials
B3441
B1200
B3562 C C Si[CH(CH3)2]3
S
p-Type Organic Semiconducting Materials D3526
N0001
S
S
S
S
S
S
S
S C C Si[CH(CH3)2]3
P0030
P1795
P1893 N NH
S
N
N
N N
S
HN N
P1628
S0220
S0504
T1196
T2269 CH3
N N N
N N
N
Cu N
N
4
S
S
4
S
S
S
N
D3526 N0001 P0030 P1795 P1893 P1628 S0220 S0504 T1196 T2269 T1812 T2233
CH3
T2233
N
Product No. Product Name B3441 B1200 B3562
N
S CH3
T1812
N
CH3
Unit Size
2,5-Bis(4-biphenylyl)thiophene Bis(ethylenedithio)tetrathiafulvalene 6,13-Bis(triisopropylsilylethynyl)pentacene (This product is unavailable for selling domestically in U.S.) 2,7-Diphenyl[1]benzothieno[3,2-b][1]benzothiophene Naphthacene Pentacene (purified by sublimation) Phthalocyanine (purified by sublimation) Picene (purified by sublimation) Pigment Blue 15 (purified by sublimation) p-Sexiphenyl α-Sexithiophene 2,2':5',2''-Terthiophene (=α-Terthienyl) N,N,N ',N '-Tetrakis(p-tolyl)benzidine N,N,N ',N '-Tetraphenylbenzidine 5,6,11,12-Tetraphenylnaphthacene (refined product of T0561)
B1641
B1694
1g 1g
100mg
100mg
5g 5g 100mg 100mg 5g 1g 1g 1g 1g 1g 1g 5g 5g 25g 1g
1g 100mg 100mg 100mg 100mg 1g 5g 250mg
H1194 F
F
F
F
F
F N F
n-Type Organic Semiconducting Materials
N N
Cu N
F
F
N N N
F
N F
F F
F
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
F
F
203
Organic Semiconducting Materials
M2088
N0755
P0972 O
O
T0078
O
OCH3
T2206 NC
O
O
O
O
O
O
C
CN F
O
F
O
T1131
O
O
NC
C
F F
S
F
S
F
4
F
S
F
CN
C2415 NC
C
CN
CH3
(CH2)11CH3
N
F
F
F
F NC
C
CN
Product No. Product Name
Unit Size
B1641 B1694 H1194
Fullerene C60 (pure) Fullerene C70 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-Hexadecafluorophthalocyanine Copper(II)
100mg
1g 100mg
(purified by sublimation)
100mg
M2088 N0755 P0972 T0078 T2206 T1131 C2415
Methyl [6.6]-Phenyl-C61-butyrate Naphthalene-1,4,5,8-tetracarboxylic Dianhydride (purified by sublimation) 3,4,9,10-Perylenetetracarboxylic Dianhydride 7,7,8,8-Tetracyanoquinodimethane Tetradecafluoro-α-sexithiophene (purified by sublimation) Tetrafluorotetracyanoquinodimethane (purified by sublimation) C60MC12
1g 100mg 5g 500g 25g 50mg 1g 100mg
1g 25g 5g 100mg
C60 & C70 (see p.196) Carbon Nanotube (see p.197) Reagents for Conducting Polymer Research (see p.210) Electroluminescence (see p.218) Phthalocyanines (see p.273) References 2006, 2007, 1) J. E. Anthony, , 5028; Y. Shirota, H. Kageyama, , 953. 2005, 70, 2509; H. Klauk, U. Zchieschang, Z. T. 2) G. Portella, J. Poater, J. M. Bofill, P. Alemany, M. Solà, 2007, Weitz, H. Meng, F. Sun, G. Nunes, D. E. Keys, C. R. Fincher, Z. Xian, , 3882. 2008, 3) H. Okamoto, N. Kawasaki, Y. Kaji, Y. Kubozono, A. Fujiwara, M. Yamaji, , 10470. 4) R. Mitsuhashi, Y. Suzuki, Y. Yamanari, H. Mitamura, T. Kambe, N. Ikeda, H. Okamoto, A. Fujiwara, M. Yamaji, N. Kawasaki, Y. 2010, Maniwa, Y. Kubozono, , 76. 2006, 5) K. Takimiya, H. Ebata, K. Sakamoto, T. Izawa, T. Otsubo, Y. Kunugi, , 12604.
204
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Charge Transfer Complexes for Organic Metals
Charge Transfer Complexes for Organic Metals The discovery in 1973 of the metal-like electronic behavior of charge transfer complexes, consisting of an electron donor, Tetrathiafulvalene (TTF) and an electron acceptor, 7,7,8,8-Tetracyanoquinodimethane (TCNQ)1)‚ has led to intensive studies of the organic metals. In 1980 Jérome2), Bechgaad3) and their co-workers have found that each complex of (TMTSF)2PF6 or (TMTSF)2ClO4 using TMTSF analogue of TTF, becomes a superconductor at very low temperatures. Afterwards, organic superconductors utilizing BEDT-TTF4), M(dmit)25) (M=Ni, Pd), etc. have successively been designed one after another. Moreover, the complexes κ-(BEDT-TTF)2Cu[N(CN)2]Br (Tc=11.6K)6), and κ-(BEDT-TTF)2Cu[N(CN)2]Cl (0.3kbar; Tc=12.8K)7) having higher Tc have been found and vigorous studies have been conducted toward the development of still higher Tc organic superconductor. B1200
S
TTF Derivatives
Donors
B1218
S
B1244
S
S
S
S
D2067
S
S
S
S
S
S
T1143
S
S
S
S
S
T1205
S
S
S
S
S
D D D D
S
T0980
S
S
S
S
S
S
S
S
S
S
SCH2CH3
S
S
CH3(CH2)17S
S
S
S(CH2)17CH3
CH3CH2S
S
S
SCH2CH3
T1377
S(CH2)17CH3
CH3(CH2)4S
S
S
S(CH2)4CH3
S
S
CH3(CH2)4S
S
S
S(CH2)4CH3
S
S
D D D
CH3S
S
S
SCH3
CH3S
S
S
SCH3
T2468 NC
CH3(CH2)17S
D
T1119
CH3CH2S
CH3 S
S
S
T1571
CH3 S
S
B1299
D
S
S
D
D
S
S
D
S
S
S
S
C
CN
. NC
C
CN
T1282
S
S
S
S
.
(BF4)2
3
Product No. Product Name B1200 B1299 B1218 B1244 D2067 T1571 T1119 T1143 T1205 T0980 T1377 T2468 T1282
Bis(ethylenedithio)tetrathiafulvalene (BEDT-TTF) Bis(ethylenedithio)tetrathiafulvalene-d8 (BEDT-TTF-d8) Bis(methylenedithio)tetrathiafulvalene (BMDT-TTF) Bis(trimethylenedithio)tetrathiafulvalene (BPDT-TTF) Dimethyltetrathiafulvalene (SDM-TTF) Tetrakis(ethylthio)tetrathiafulvalene Tetrakis(methylthio)tetrathiafulvalene (TMT-TTF) Tetrakis(octadecylthio)tetrathiafulvalene (TODT-TTF) Tetrakis(pentylthio)tetrathiafulvalene (TPT-TTF) Tetrathiafulvalene (TTF) Tetrathiafulvalene-d4 (TTF-d4) Tetrathiafulvalene - 7,7,8,8-Tetracyanoquinodimethane Complex Tris(tetrathiafulvalene) Bis(tetrafluoroborate) Complex
Unit Size 100mg
1g
5g 100mg 100mg 100mg 100mg 1g 100mg 100mg 100mg 100mg 1g 5g 25g 100mg 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
205
Charge Transfer Complexes for Organic Metals
B2309
B1466 NC
C
CN O(CH2)2OH
TCNQ Derivatives
Acceptors
D3200
D2021 NC
C
CN
C
NC
C
NC
CN
T0078
C
CN
NC
C
C
T1246
NC
CN
NC
CN
NC
C C
CN
NC
NC
CN
C
F
F
S
S
F
F
S
S
NC
C
C
CN
.
CN
NC
C
CN
Product No. Product Name B2309 B1466 D3200 D2021 F0509 T0077 T1246 T0078 T1131 T2468
Unit Size
2,5-Bis(2-hydroxyethoxy)-7,7,8,8-tetracyanoquinodimethane Bis(tetrabutylammonium) Tetracyanodiphenoquinodimethanide 2,5-Difluoro-7,7,8,8-tetracyanoquinodimethane 2,5-Dimethyl-7,7,8,8-tetracyanoquinodimethane 2-Fluoro-7,7,8,8-tetracyanoquinodimethane Tetracyanoethylene 11,11,12,12-Tetracyanonaphtho-2,6-quinodimethane 7,7,8,8-Tetracyanoquinodimethane (TCNQ) Tetrafluorotetracyanoquinodimethane (purified by sublimation) Tetrathiafulvalene - 7,7,8,8-Tetracyanoquinodimethane Complex
B1350
B1437
S S
B1371 NC
CN
S Ni
S
S
S
S
CN
S
S
S S
S
(C18H37)2(CH3)2N
2 (C4H9)4N
S
S
Au S
S
S
2
S S
S
S
S
S
S
S
2
S
Pt
S S
S
S
NC
S
Ni S
S
NC [CH3(CH2)3]4N
S
S
S
S
S
S
CN
S
S
S
S
S
S
S
(C4H9)4N
CN
S
S
S
S
Ni
S
(C4H9)4P
S Zn S
206
S
2 (C4H9)4N
T0279
CH3
2
S
Zn S
Ni
S
S
T1416
S S
S S
2 (C4H9)4N
T1415
S S
B1221
S
S
T1272
S
5g 100mg 100mg 100mg 100mg 5g 25g 100mg 5g 25g 100mg 1g 1g
2 (C4H9)4N
2
S
S Pd
S
1g
B1438
S
D2134 S
NC
S
S Ni
Metal Dithiolenes
CN
T2468
CN
CN
CN
CN
C
NC
T1131 NC
C
CN
F
CH3
F
2
CN
C
CH3
F
CN 2 (C4H9)4N
NC
T0077 NC
CN
NC
HO(CH2)2O
F0509 NC
CN
NC
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Charge Transfer Complexes for Organic Metals
Product No. Product Name B1350 B1437 B1438 B1221 B1371 D2134 T1272 T1415 T1416 T0279
Unit Size
Bis(dithiobenzil)nickel(II) Bis(tetrabutylammonium) Bis(1,3-dithiole-2-thione-4,5-dithiolato)palladium(II) Bis(tetrabutylammonium) Bis(1,3-dithiole-2-thione-4,5-dithiolato)platinum(II) Bis(tetrabutylammonium) Bis(1,3-dithiole-2-thione-4,5-dithiolato)zinc Complex Bis(tetrabutylammonium) Bis(maleonitriledithiolato)nickel(II) Complex Dioctadecyldimethylammonium Bis(1,3-dithiole-2-thione-4,5-dithiolato)aurate(III) Tetrabutylammonium Bis(1,3-dithiole-2-thione-4,5-dithiolato)nickel(III) Complex Tetrabutylammonium Bis(maleonitriledithiolato)nickel(III) Complex Tetrabutylphosphonium Bis(1,3-dithiole-2-thione-4,5-dithiolato)nickel(III) Complex (Toluene-3,4-dithiolato)zinc(II)
B0089
1g 100mg
25g 1g 100mg 5g 25g 1g 100mg 100mg 1g 1g 1g 5g
B1416
T0617 NC
O
O
C CN Br
Other Donors & Acceptors
Br O
B1601
B1595
Br
Cl
Br
O
D2152
O
D3392
O
CH3
O Cl
NC
Cl
N
Cl
N
CH3
CH3CH2 C H3C
NH2
O
D1070
Br
C CH2CH3 H3C
CH3
Cl
D0343
CH3
NH2 Cl
O
D2249 O
D0101 O
Cl
Cl
CH3 O
Br O
C1336 O
O
C CN
NC
T0061
O
Br
Cl
Br O
D2250
D1956
M1045
CH3
CH3
OCH3
P0106 O
O
O CH3
CH3
O
D2234
O OCH3
NC O
O
H N
OCH3
OCH3
CH3O
S O
O
O
T1503
T0790
(CH3)3C
C(CH3)3
O
O
(CH3)3C
C(CH3)3
T0499
O
T1221
T1023
O
CH3
F
F
(CH3)2N (CH3)2N
F
NH2
N(CH3)2 CH3
O
CH3
N(CH3)2 H2N
F
T0151 CH3
CH3 N
CH3
CH3
N CH3
. 2HCl
T0875 NO2
NO2
O2N
NO2 O
O2N
NO2 NC
C
CN
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
207
Charge Transfer Complexes for Organic Metals
Product No. Product Name B0089 B1416 T0617 B1601 B1595 T0061 C1336 D0101 D2152 D2249 D0343 D1070 D3392 D2250 D1956 D2234 M1045 P0106 T1503 T0790 T1221 T1023 T0151 T0499 T0875
Unit Size
1,4-Benzoquinone 1,3-Bis(dicyanomethylidene)indan Bromanil 2-Bromo-1,4-benzoquinone 2-Bromo-5-methyl-1,4-benzoquinone Chloranil 2-Chloro-5-methyl-1,4-benzoquinone 1,5-Diaminonaphthalene 2,5-Di-tert-amylbenzoquinone 2,5-Dibromo-1,4-benzoquinone 2,5-Dichloro-1,4-benzoquinone 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone 5,10-Dihydro-5,10-dimethylphenazine 2,5-Dimethoxy-1,4-benzoquinone 2,3-Dimethoxy-5-methyl-1,4-benzoquinone 2,6-Dimethyl-1,4-benzoquinone Methoxybenzoquinone Phenothiazine 3,3',5,5'-Tetra-tert-butyl-4,4'-diphenoquinone Tetrafluoro-1,4-benzoquinone Tetrakis(dimethylamino)ethylene 3,3',5,5'-Tetramethylbenzidine N,N,N ',N '-Tetramethyl-1,4-phenylenediamine Dihydrochloride 2,4,7-Trinitro-9-fluorenone (wetted with ca. 20% Water, containing 5g on a dry weight basis) 2,4,7-Trinitro-9-fluorenylidenemalononitrile
B1322
B1199
25g
500g 5g 25g 1g 5g 500g 5g 500g 5g 5g 5g 250g 1g 25g 5g 25g 5g 500g 1g 5g 25g 25g 25g 5g 5g
5g
25g 25g 1g 1g 25g 5g 1g 5g 1g 25g
1g
1g 5g 5g 1g
1g
1g
B1272 O
SH
S
S
SH
C
S
Synthetic Intermediates
S
S
S
S
S
S
S
S
O
S
S
C
O
O
B2228
B2233
NC(CH2)2S
B1778
NC(CH2)2S
S
CH3S
S
S S
NC(CH2)2S
D3252
CH3S
S
S
S
O S
NC(CH2)2S
D3992
B1777
CH3S
D2127
S
S
CH3S
D1930
NC
S
NC
S
O
D2133
O
E0429
O S S
CH3O C
O OCH3
NaS
S
SNa
S
S
CH3O C
S
S
S
S
S
S
P OCH3
NC
S
S
CN
O
E0460
H1163
S
M1112
S
S
S
M1154
S
S
O S
208
S
P1635
S
S
S CH3(CH2)5
S
S
S
S
S
O S
S
S
S
S
S
CH3CH2CH2
S
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Charge Transfer Complexes for Organic Metals
T1132
T0266
S
HS
S
O
O S
S
HS
CH3
Product No. Product Name B1322 B1199 B1272 B2228 B2233 B1778 B1777 D3252 D3992 D2127 D1930 D2133 E0429 E0460 H1163 M1112 M1154 P1635 T1132 T0266
1,2-Benzenedithiol 4,5-Bis(benzoylthio)-1,3-dithiole-2-thione Bis(carbonyldithio)tetrathiafulvalene 4,5-Bis(2-cyanoethylthio)-1,3-dithiole-2-thione 4,5-Bis(2-cyanoethylthio)-1,3-dithiol-2-one 4,5-Bis(methylthio)-1,3-dithiole-2-thione 4,5-Bis(methylthio)-1,3-dithiol-2-one 4,5-Dicyano-1,3-dithiol-2-one Dimethyl 1,3-Benzodithiol-2-ylphosphonate Dimethyl 1,3-Dithiole-2-thione-4,5-dicarboxylate Disodium Dimercaptomaleonitrile 1,3-Dithiole-2-thione 4,5-Ethylenedithio-1,3-dithiole-2-thione 4,5-Ethylenedithio-1,3-dithiol-2-one 5-Hexyl-1,3-dithiolo[4,5-d][1,3]dithiole-2-thione 4,5-Methylenedithio-1,3-dithiole-2-thione 4,5-Methylenedithio-1,3-dithiol-2-one 5-Propyl-1,3-dithiolo[4,5-d][1,3]dithiole-2-thione 1,3,4,6-Tetrathiapentalene-2,5-dione Toluene-3,4-dithiol
Unit Size 1g 1g
1g 5g 1g
100mg 250mg 1g 5g 1g 5g
5g 5g 1g 1g 1g 1g 1g 1g 1g 10g 5g 5g 25g 5g 1g 1g 1g 1g 25g 25g
References 1) J. Ferraris, D. O. Cowan, V. Walatka, Jr., J. H. Perlstein, . 1973, , 948; L. B. Coleman, M. J. Cohen, D. J. Sandman, F. G. Yamagishi, A. F. Garito, A. J. Heeger, . 1973, , 1125. 2) D. Jérome, A. Mazaud, M. Ribault, K. Bechgaard, . 1980, , L-95. 3) K. Bechgaard, K. Carneiro, M. Olsen, F. B. Rasmussen, C. S. Jacobsen, . 1981, , 852. 4) S. S. P. Parkin, E. M. Engler, R. R. Schumaker, R. Lagier, V. Y. Lee, J. C. Scott, R. L. Greene, . 1983, , 270. 5) M. Bousseau, L. Valade, J.-P. Legros, P. Cassoux, M. Garbauskas, L. V. Interrante, . 1986, , 1908. 6) A. M. Kini, U. Geiser, H. H. Wang, K. D. Carlson, J. M. Williams, W. K. Kwok, K. G. Vandervoort, J. E. Thompson, D. L. Stupka, D. Jung, M.-H. Whangbo, . 1990, , 2555. 7) J. M. Williams, A. M. Kini, H. H. Wang, K. D. Carlson, U. Geiser, L. K. Montgomery, G. J. Pyrka, D. M. Watkins, J. M. Kommers, S. J. Boryschuk, A. V. S. Crouch, W. K. Kwok, J. E. Schirber, D. L. Overmyer, D. Jung, M.-H. Whangbo, . 1990, , 3272. 8) H. Kobayashi, T. Udagawa, H. Tomita, K. Bun, T. Naito, A. Kobayashi, . 1993, 1559; H. Kobayashi, H. Tomita, T. Naito, H. Tanaka, A. Kobayashi, T. Saito, . 1995, 1225; K. Takimiya, Y. Kataoka, Y. Aso, T. Otsubo, H. Fukuoka, S. Yamanaka, . 2001, , 1122; J. Yamada, M. Watanabe, H. Akutsu, S. Nakatsuji, H. Nishikawa, I. Ikemoto, K. Kikuchi, . 2001, , 4174.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
209
Reagents for Conducting Polymer Research
Reagents for Conducting Polymer Research In 1977, Shirakawa and co-workers reported that thin films of the semi-conducting polymer polyacetylene show a dramatic increase in electrical conductivity when doped with controlled amounts of iodine.1) Their reports triggered intensive R&D into the electrical conductivity of plastic materials. Studies of conducting polymers began and, as a result, many π-conjugated polymers such as polypyrrole2), polythiophene3), polyaniline4) and polyphenylenevinylene5) have been developed. Among these polymers, many of them have been utilized practically. One example is an electrolytic condenser using polypyrrole. This condenser has characteristic features such as being compact and lightweight, as well as having high-capacity and high-frequency compliance. These features have achieved a downsizing and weightsaving in electronic devices, and are utilized currently in some mobile phones. Thereby, conducting polymers are widely used for electronic devices vital to our everyday life. These and many other achievements were the reasons Shirakawa received to the Nobel Prize Award in 2000. Moreover, conducting polymers have been applied to solar cell materials. For instance, Kim have reported the synthesis of the co-polymers 3 and 4, using 4,7-dibromo-2,1,3-benzothiadiazole (1) and 4,7-dibromo-2,1,3-benzoselenadiazole (2) as starting materials, respectively. According to their results, the bulk heterojunction solar cells composed of 3 or 4 with PC71BM give power conversion efficiencies of 1.12%6) and 1.34%7), respectively. Thus, further applications using conducting polymers can be fully expected in many areas. R1O
OR1
Br N
S
N
N S S
N
S n
Br
3 1 R2
Br
R2 N
Se
N
N Se S
N
S
S
S n
4
Br 2
The page below shows the monomers and oligomers for conducting polymer research. M0440
E0378
P1128
CH3
3-Alkylthiophenes
B1458
S
P1127
S
(CH2)9CH3
210
S
(CH2)6CH3 S
U0056
(CH2)8CH3
O0213
(CH2)5CH3 S
D2098
(CH2)7CH3 S
D2016
(CH2)10CH3 S
CH2CH2CH3 S
H0722
(CH2)4CH3 S
N0533
S
H0756
(CH2)3CH3 S
CH2CH3
O0245
(CH2)11CH3 S
(CH2)17CH3 S
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Reagents for Conducting Polymer Research
Product No. Product Name M0440 E0378 P1128 B1458 P1127 H0756 H0722 O0213 N0533 D2098 U0056 D2016 O0245
Unit Size
3-Methylthiophene 3-Ethylthiophene 3-Propylthiophene 3-Butylthiophene 3-Pentylthiophene 3-Hexylthiophene 3-Heptylthiophene 3-n-Octylthiophene 3-Nonylthiophene 3-Decylthiophene 3-Undecylthiophene 3-Dodecylthiophene 3-Octadecylthiophene
1g 1g
1g
B3464
CH3
CH3 O
O
CH3
B
Thiophene Derivatives
CH3
S
B1838
500g 25ml 5g 5g 5g 25g 5g 25g 5g 5g 5g 25g 5g
B3363
S
B1276
25g 5ml 1g 1g 1g 5g 1g 5g 1g 1g 1g 5g 1g
S
O
O
CH3
B1874
CH3
B
S
CH3 CH3
B3507
B1540
(CH2)5CH3 O S
S
S
B1541
S
C H
B3385
CH3
Br
O Br
S
S
C H
B2058
S
CH3
Br
B1067
S
Br
B2862
Br
Br O
S
S
B2934
CH3
B3386
Br
Br
S
C1801
S
B(OH)2
C1192
Cl
CH3 S
O Br
C OH
C OH
S
S
D2755
H2N
. 2HCl
S
Br
D3701
Br
S
Cl
D3799
NH2
S
D3896
C H
S
O
D2378
CN
S
Br
C H
C1344
S
B2302
O S
Br
S
S
D3800
S
S
Br
D3928
Br
S
S Br
D3823
S S
Br
D2077
CH3(CH2)5 (CH2)5CH3
F
F
S S
Br
S
Br
(CH3)3Si
S
Si(CH3)3
S S
S
B(OH)2
S
CH
CHCH
CH
S
CH3(CH2)5
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
211
Reagents for Conducting Polymer Research
D3712
D2073
D2074
E0741
O
F0548
O S
S
S S
O
CH
CH
CH
CH
O
O
S
H C
S
S
S
B(OH)2
S
H1298
H1294
I0380
M1093
O0313
CH3(CH2)5 CH3 CH3
CH3
O
B
CH3
S
B CH3
O
CH3
(CH2)5CH3
O
I
OCH3
S
O
S
S
S
CH3
S
6
S
S
4
S
CH3
P1126
Q0078
Q0079
S
S
2
S
S0505
S
S
S
3
S0504
S
S
5
S
S
S
T1196
T1805
T2639
T2699
T2206 Br
O
S
S
S
S
S
S
C H
O
O
H C
S
S
S
C H
Br
S
S
Br
F
F
F F
S
F
S
F
4
F
S
Br
T1084
T2729
T2621
O
T0725
T0864 O
S
C OH S
S
S
S
T1152
T2388
S
B(OH)2
T2347
C H S
T1475
T1354 O
O
O
O S
S
C H
C OH
CH2CH2OH
C H
CH2 C OH
HO C
O S
C OH
CH
C OH O
S S
O
T1660
T0956
CH2OH S
Br Br
S
Br
Product No. Product Name B3464 B3363 B1276 B1838 B1874 B3507
212
C H
O
Benzo[1,2-b:4,5-b']dithiophene 5,5'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2'-bithiophene 2,2'-Bithiophene 2,2'-Bithiophene-5-carboxaldehyde 5-Bromo-2,2'-bithiophene-5'-carboxaldehyde 2-Bromo-3-hexylthiophene
Unit Size 1g 1g 1g
10g 5g 1g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
5g 5g 25g 25g 5g 5g
F
Reagents for Conducting Polymer Research
Product No. Product Name B1540 B1541 B3385 B2058 B1067 B2862 B2934 B3386 B2302 C1801 C1192 C1344 D2378 D2755 D3799 D3800 D3896 D3701 D3928 D3823 D2077 D3712 D2073 D2074 E0741 F0548 H1298 H1294 I0380 M1093 O0313 P1126 Q0078 Q0079 S0505 S0504 T1196 T1805 T2639 T2699 T2206 T1084 T2729 T2621 T0725 T0864 T1152 T2388 T2347 T1475 T1354 T1660 T0956
Unit Size
2-Bromo-5-methylthiophene (stabilized with Copper chip + NaHCO3) 3-Bromo-4-methylthiophene 4-Bromo-2-methylthiophene 5''-Bromo-2,2':5',2''-terthiophene-5-carboxaldehyde 3-Bromothiophene 5-Bromo-2-thiopheneboronic Acid (contains varying amounts of Anhydride) 3-Bromothiophene-2-carboxaldehyde 4-Bromo-2-thiophenecarboxylic Acid 5-Bromo-2-thiophenecarboxylic Acid 2-Chloro-3-methylthiophene 3-Chlorothiophene 3-Cyanothiophene 3,4-Diaminothiophene Dihydrochloride 5,5'-Dibromo-2,2'-bithiophene 2,6-Dibromodithieno[3,2-b:2',3'-d]thiophene 3,5-Dibromodithieno[3,2-b:2',3'-d]thiophene 2,5-Dibromo-3-hexylthiophene 3,4-Difluoro-2,5-bis(trimethylsilyl)thiophene 3,4'-Dihexyl-2,2'-bithiophene Dithieno[3,2-b:2',3'-d]thiophene-2-boronic Acid (contains varying amounts of Anhydride) 1,4-Di(2-thienyl)-1,3-butadiene 1,4-Di(2-thienyl)-1,4-butanedione cis-1,2-Di(2-thienyl)ethylene trans-1,2-Di(2-thienyl)ethylene 3,4-Ethylenedioxythiophene 5'-Formyl-2,2'-bithiophene-5-boronic Acid (contains varying amounts of Anhydride) 3-Hexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene 4-Hexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene 3-Iodothiophene 3-Methoxythiophene α-Octithiophene 3-Phenylthiophene α-Quarterthiophene α-Quinquethiophene α-Septithiophene α-Sexithiophene 2,2':5',2''-Terthiophene (=α-Terthienyl) 2,2':5',2''-Terthiophene-5-carboxaldehyde 2,2':5',2''-Terthiophene-5,5''-dicarboxaldehyde 3,3',5,5'-Tetrabromo-2,2'-bithiophene Tetradecafluoro-α-sexithiophene (purified by sublimation) 3-Thenoic Acid Thieno[2,3-b]thiophene Thieno[3,2-b]thiophene-2-boronic Acid (contains varying amounts of Anhydride) 2-Thiophenaldehyde (stabilized with HQ) 3-Thiophenaldehyde Thiophene-3-acetic Acid 2,3-Thiophenedicarboxaldehyde 2,5-Thiophenedicarboxylic Acid 3-Thiopheneethanol 3-Thiophenemalonic Acid 3-Thiophenemethanol 2,3,5-Tribromothiophene
A1015
A1022
5g 5g 5g 100mg 1g 25g 1g 1g 5g 5g 1g 5g 5g 5g 100mg 1g 200mg 200mg
1g 200mg 1g 1g 1g 5g 1g 1g 1g 1g
100mg 1g
1g 5g 1g 25ml 5g 5g 1g 5g 5g 5g 5g 25g
25g 25g 25g 5g 250g 5g 25g 25g 5g 25g 25g 25g 1g 5g 1g 1g 5g 1g 5g 1g 5g 5g 1g 5g 25g 1g 5g 5g 5g 5g 100mg 5g 100mg 100mg 100mg 1g 5g 1g 1g 5g 50mg 25g 5g 1g 500ml 25g 25g 5g 25g 25g 25g 25g 250g
B2335
O C CH3
Pyrroles
N
N
N
NH2
CH2
CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
213
Reagents for Conducting Polymer Research
B1622
B1623
C1347
D3876
N
N
N
CH2CH2Br
CH2CH2CH2Br
CH2CH2Cl
H0809
H0826
E0444
S
H0827
N H
N
S
CH2CH3
M0414
N0584 N
(CH2)6CH3 N H
N
N
N
CH2CH2OH
CH2CH2CH2OH
CH3 NO2
N0502
O0219
O0242
O0241
NO2
(CH2)7CH3 N
N H
N H
(CH2)7CH3
T1386
T1677
O N H
N
N
(CH2)17CH3
P0574
P1122
N S O
CH3
N CH3 CH3 CH3 HC Si CH CH 3 CH CH3 CH3
Product No. Product Name A1015 A1022 B2335 B1622 B1623 C1347 D3876 E0444 H0809 H0826 H0827 M0414 N0584 N0502 O0219 O0242 O0241 P1122 P0574 T1386 T1677
Unit Size
3-Acetyl-1-methylpyrrole 1-Aminopyrrole 1-Benzylpyrrole 1-(2-Bromoethyl)pyrrole 1-(3-Bromopropyl)pyrrole 1-(2-Chloroethyl)pyrrole 2,5-Di(2-thienyl)-1H-pyrrole 1-Ethylpyrrole 3-Heptylpyrrole 1-(2-Hydroxyethyl)pyrrole 1-(3-Hydroxypropyl)pyrrole 1-Methylpyrrole 1-(4-Nitrophenyl)pyrrole 3-Nitropyrrole 1-Octadecylpyrrole 1-n-Octylpyrrole 3-n-Octylpyrrole 1-Phenylpyrrole Pyrrole 1-(p-Toluenesulfonyl)pyrrole 1-(Triisopropylsilyl)pyrrole
5ml 1g 1g 1g
1g 1g 1g 25ml 1g 1g 5g 1g 10g 25ml 5ml
A1508
B1967 NH2
Carbazoles
214
N CH2CH3
B2864
N N
N
N
N C O
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
25ml 5g 5g 5g 5g 5g 1g 5g 5g 5g 1g 500ml 1g 5g 5g 25g 5g 25g 500ml 5g 25ml
Reagents for Conducting Polymer Research
B3558
B2804
B2805 O
B2713
O
C H
C0032
O
H C
C H N
N CH2
C1031
N
N
CH2
CH2
C0714
N
C Cl
D3932
D2982
D2981
Br
E0359
C H
CH3
N
N H
CH2CH3
M0960
N H
C CH3
H3C
H1014
Br
CH3
H3C C
N
Br
O H3C
N
N H
E0071 E0247
Br
Br
Br Br
D3952
Br
D2983
NH2 N H
K
O
N H
D2116 H2N
N
N
P1492
N
CH2CH3
CH2CH3
P0656
T0159
OH
O2N
NO2
N N H
T1934
N
N
CH3
CHCH2
NO2
n
N H
NO2
V0021 N
N
N
N
CH
CH2
Product No. Product Name A1508 B1967 B2864 B3558 B2804 B2805 B2713 C0032 C1031 C0714 D2116 D3932 D2983 D2982 D2981 D3952 E0071 E0247 E0359 H1014 M0960 P1492
3-Amino-9-ethylcarbazole 9-(1H-Benzotriazol-1-ylmethyl)-9H-carbazole 9-Benzoylcarbazole 9-Benzylcarbazole 9-Benzylcarbazole-3-carboxaldehyde 9-Benzylcarbazole-3,6-dicarboxaldehyde 4,4'-Bis(9H-carbazol-9-yl)biphenyl Carbazole Carbazole-9-carbonyl Chloride Carbazole Potassium Salt 3,6-Diaminocarbazole 2,7-Dibromocarbazole 3,6-Dibromocarbazole 3,6-Dibromo-9-ethylcarbazole 3,6-Dibromo-9-phenylcarbazole 3,6-Di-tert-butylcarbazole 9-Ethylcarbazole 9-Ethylcarbazole N-Ethylcarbazole-3-carboxaldehyde 4-Hydroxycarbazole 9-Methylcarbazole 9-Phenylcarbazole
Unit Size 1g 1g 1g
1g
1g
1g 25g 5g 1g 1g 5g 1g 1g 25g
1g 1g
5g 5g 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 5g 5g 5g 5g 100mg 5g 500g 25g 25g 5g 5g 25g 5g 5g 1g 500g 25g 25g 25g 25g 25g
215
Reagents for Conducting Polymer Research
Product No. Product Name P0656 T0159 T1934 V0021
Unit Size
Poly(N-vinylcarbazole) 1,3,6,8-Tetranitrocarbazole (wetted with ca. 40% Water, containing 25g on a dry weight basis) 1,3,5-Tri(9H-carbazol-9-yl)benzene (purified by sublimation) 9-Vinylcarbazole
B0921
5g 1g
B1336
25g 25g 5g 25g
B2843
Cl
N
Others (see also p.282 Reagents for High-Performance Polymer Research) B3573
B3089 CH3
O CH3
B
N
S
N
N O
O
H C
C H
Cl
B2844
B3560
B2633
Br
CH3 CH3 CH3 O O B
N
N
Br
N S
Br
N
N
N
O
CH3 CH3 CH3
CH3
D3944
Br
CH3
D3842
D3302
D3303
Br
Br
D3872
Br
Br
N
N
N
Se
S
N
Br
Br N
N
Br
Br Br
D1910
A1122
Br
Br
N0536
Br
O
H N
P0972
N0369 N0755
O
O
NH2
O
O
N C CH O
N H
S0829
O
O
O
O
O
O
O
P0984
O
S0831
O
O
T2597
T1361 Br
O
O
B(OH)2 HN
Br
Br
Br
Br
NH
Se O
O
N Br
Br
T2310 O C H
N O H C
O C H
Product No. Product Name B0921 B1336 B2843 B3573 B3089 B2844
216
2,1,3-Benzothiadiazole N,N '-Bis(4-chlorophenyl)-N,N '-diphenyl-1,4-phenylenediamine Bis(4-formylphenyl)phenylamine 4,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,1,3-benzothiadiazole 4-Bromo-4',4''-dimethyltriphenylamine 4-Bromo-4'-(diphenylamino)biphenyl
Unit Size 10g
250mg
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
25g 1g 1g 1g 1g 1g
Reagents for Conducting Polymer Research
Product No. Product Name B3560 B2633 D3944 D3842 D3302 D3303 D3872 D1910 A1122 N0536 N0369 N0755 P0972 P0984 S0829 S0831 T2597 T1361 T2310
2-Bromo-9,9'-spirobi[9H-fluorene] 4-Bromotriphenylamine 4,7-Dibromo-2,1,3-benzoselenadiazole 4,7-Dibromo-2,1,3-benzothiadiazole 4,4'-Dibromo-4''-cyclohexyltriphenylamine 4,4'-Dibromo-4''-phenyltriphenylamine 2,2'-Dibromo-9,9'-spirobi[9H-fluorene] 4,4'-Dibromotriphenylamine 3-Ethynylaniline 1,4,5,8-Naphthalenetetracarboxdiimide Naphthalene-1,4,5,8-tetracarboxylic Dianhydride Naphthalene-1,4,5,8-tetracarboxylic Dianhydride (purified by sublimation) 3,4,9,10-Perylenetetracarboxylic Dianhydride 3,4,9,10-Perylenetetracarboxylic Diimide Selenophene 9,9'-Spirobi[9H-fluorene]-2-boronic Acid 2,2',7,7'-Tetrabromo-9,9'-spirobi[9H-fluorene] Tris(4-bromophenyl)amine Tris(4-formylphenyl)amine
Unit Size 5g 1g
10g
5g
1g 25g 1g 25g 1g 1g 1g
5g 25g 1g 25g 1g 1g 1g 100mg 10g 5g 250g 5g 500g 25g 5g 5g 5g 25g 500mg
References 1977, 578. 1) H. Shirakawa, E. J. Luois, A. G. MacDiarmid, C. K. Chiang, A. J. Heeger, 2) K. K. Kanazawa, A. F. Diaz, R. H. Geiss, W. D. Gill, J. F. Kwak, J. A. Logan, J. F. Rabolt, G. B. Street, 1979, 854; M. Salmon, A. F. Diaz, J. A. Logan, K. Krounbi, J. Bargon, 1982, , 1986, 265; M. Ogasawara, K. Funahashi, T. Demura, T. Hagiwara, K. Iwata, , 62. 1985, 713; S. Hotta, 1987, 3) M. Sato, S. Tanaka, K. Kaeriyama, , 103. 1984, 4) T. Kobayashi, H. Yoneyama, H. Tamura, , 281; J.-C. Chiang, A. G. MacDiarmid, 1986, , 193. 1979, 5) G. E. Wnek, J. C. W. Chien, F. E. Karasz, C. P. Lillya, , 1441; D. R. Ganon, J. D. Capistran, F. E. Karasz, 1987, R. W. Lenz, S. Antoun, , 567. 2010, 6) J. Kim, S. H. Park, S. Cho, Y. Jin, J. Kim, I. Kim, J. S. Lee, J. H. Kim, H. Y. Woo, K. Lee, H. Suh, , 390. 7) I. H. Jung, H. Kim, M.-J. Park, B. Kim, J.-H. Park, E. Jeong, H. Y. Woo, S. Yoo, H.-K. Shim, 2010, , 1423.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
217
Electroluminescence
Electroluminescence Electroluminescence (EL) is a phenomenon where electrical energy is directly converted into light. With the growing interest in EL, considerable attention has been directed toward organic electroluminescent materials and devices since Tang and Van Slyke reported the first high efficiency organic light emitting diode (OLED) in 1987.1) In recent years, OLED products have become commercially available in a limited range. OLEDs are self-emitting devices requiring low operating voltage and offer several advantages including wide viewing angle, fast response time, high brightness, etc.2-5) The OLED technology will play a leading role in display and lighting applications. An OLED device comprises a single or multi organic layers sandwiched between electrodes, typically emissive layer, hole-transport layer, electron-transport layer, etc. Emission colors are tunable by adding a small amount of dopant into an emissive layer.6) Polymeric and dendritic materials as well as small molecules have become a major focus of interest in terms of the ease of processing. 7-10)
B2077
B2078 S
O
N
Metal Complexes
Metal Complexes & Ligands
B1678
P1766
P1005 P1006 N
O
N N
N N
N
S
O
T1735
S
O Eu
Cu
N
N
CH O
N
N
N
CF3
N
N
N
N
O
N
3
. 6H2O
N
3
T1946
N
O
N Ir
Ir
T1527 T2238 O
N
N
N
Ir
N
O
N Al O
O
N
N
3
Product No. Product Name
218
O Eu
2Cl
Ru
CH3
B2077 B2078 B1678 P1005 P1006 P1766 T1655 T1735 T2557 T2685 T1946 T1527 T2238
O
N
N
N
T2685
CH3
O Zn
T1655
N
N
. xH2O T2557
O
2
Zn O
N
O Zn
Bis[2-(2-benzothiazolyl)phenolato]zinc(II) Bis[2-(2-benzoxazolyl)phenolato]zinc(II) Bis(8-quinolinolato)zinc(II) Hydrate Copper(II) Phthalocyanine (α-form) Copper(II) Phthalocyanine (β-form) (1,10-Phenanthroline)tris[4,4,4-trifluoro-1-(2-thienyl)-1,3-butanedionato]europium(III) Tris(2,2'-bipyridyl)ruthenium(II) Chloride Hexahydrate Tris(1,3-diphenyl-1,3-propanedionato)(1,10-phenanthroline)europium(III) Tris(2,4-pentanedionato)iridium(III) Tris[1-phenylisoquinoline-C 2,N]iridium(III) (purified by sublimation) Tris(2-phenylpyridinato)iridium(III) (purified by sublimation) Tris(8-quinolinolato)aluminum Tris(8-quinolinolato)aluminum (purified by sublimation)
Unit Size 1g 5g 25g 25g 1g 1g
25g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
5g 5g 25g 250g 500g 1g 5g 5g 1g 100mg 200mg 250g 5g
Electroluminescence
P0052
B1733
O
O
C
C CH2 C O
T2037
N
CH3
M1132 O
O
CH3 CF3
O
C CH2 C
O
CH3
O
O
CH3
O N
O
CH3
H0476 O
CH3
OCH3
E0405
O
CH3
O
C CH2
CH3
CH3 CH3
O
CH3
D2512
CH3 CH3
CH3
D0910 O
O CH3O
Propanediones
D1678
D2413
CF3
O
CH3
CH3 CH3
CH3
T0434 O
CH2
C
(CF2)6CF3
C
(CF2)6CF3
O CF3
O CH3
O
Product No. Product Name
Unit Size
P0052 B1733 D2413 D0910 D1678 D2512 E0405 H0476 M1132 T2037 T0434
25ml 5g 5g 25g 5g
Acetylacetone 1,3-Bis(4-methoxyphenyl)-1,3-propanedione 2,6-Dimethyl-3,5-heptanedione 1,3-Diphenyl-1,3-propanedione Dipivaloylmethane 1,3-Di(2-pyridyl)-1,3-propanedione 3-Ethyl-2,4-pentanedione Hexafluoroacetylacetone 3-Methyl-2,4-pentanedione 9H,9H-Triacontafluoro-8,10-heptadecanedione Trifluoroacetylacetone
B2387
B0838 Br
D1235
M0523 CH3
Br
CH3
CH3
Phenanthrenes
P0079 P1310 P0331
500ml 25g 25g 500g 25g 5g 5ml 5g 25g 5ml 25ml 100mg 25g 100g
P1093
B(OH)2
Product No. Product Name B2387 B0838 D1235 M0523 P0079 P1310
3-Bromophenanthrene 9-Bromophenanthrene 3,6-Dimethylphenanthrene 3-Methylphenanthrene Phenanthrene Phenanthrene
Unit Size 100mg 250g 100mg 100mg 25g 500g 25g 500g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
219
Electroluminescence
Product No. Product Name P0331 P1093
Unit Size
Phenanthrene Zone Refined (number of passes:30) 9-Phenanthreneboronic Acid (contains varying amounts of Anhydride)
D0905 B2695
D0711 B2694
100mg
B2632
C1560 Cl
Br
N
N
N
N
Phenanthrolines N
N
CH3
C0786
N
CH3
D2565
D1559
(CH2)3CH3
N
N
N
N CH3(CH2)3
N0423
N N
P0221 CH3
N CH3
. HCl . H2O
N
N
N
N
N
CH3 CH3
. H2O CH3
. 1/2H2O
CH3
Product No. Product Name D0711 B2694 D0905 B2695 B2632 C1560 C0786 D2565 D0772 D1559 D3849 D0771 N0423 P0221 T0847
Unit Size
Bathocuproine Bathocuproine (purified by sublimation) Bathophenanthroline Bathophenanthroline (refined product of D0905) 3-Bromo-1,10-phenanthroline 2-Chloro-1,10-phenanthroline 5-Chloro-1,10-phenanthroline 2,9-Dibutyl-1,10-phenanthroline 4,7-Dimethyl-1,10-phenanthroline 5,6-Dimethyl-1,10-phenanthroline 2,9-Diphenyl-1,10-phenanthroline Neocuproine Hemihydrate Neocuproine Hydrochloride 1,10-Phenanthroline Monohydrate 3,4,7,8-Tetramethyl-1,10-phenanthroline
D3413
1g 1g
100mg 100mg 100mg
1g 1g 1g 1g
M2101
M2001
CH3 N
N F
220
5g 1g 5g 1g 200mg 1g 1g 1g 100mg 100mg 1g 25g 25g 25g 5g
M0932
F
Phenylpyridines
N
T0847 N
N
N
CH3
CH3 CH3
CH3
CH3
CH3
D3849
N
Cl
D0771
N
D0772
N
1sample 1g
N
CH3
N
OCH3
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Electroluminescence
P1731
P1039
P1889
P1671
T1228
O C H
N
O C H N
N
N
N CH3
T2688
N CF3
Product No. Product Name D3413 M2101 M2001 M0932 P1731 P1039 P1889 P1671 T1228 T2688
Unit Size
2-(2,4-Difluorophenyl)pyridine 2-(4-Methoxyphenyl)pyridine 2-Methyl-6-phenylpyridine 3-Methyl-2-phenylpyridine 1-Phenylisoquinoline 2-Phenylpyridine 3-(2-Pyridyl)benzaldehyde 4-(2-Pyridyl)benzaldehyde 2-(p-Tolyl)pyridine 2-[4-(Trifluoromethyl)phenyl]pyridine
B1190
1g
5g 1g 5g 1g 5g 1g
B3324
Br
Br
N OH
N
M0420
N OH
P0531 F
N
N
CH3CH2CH2
N OH
OH
H0305
N
CH3
OH
N OH
Product No. Product Name B1190 B3324 C0187 C0645 D0208 D0412
I OH
OH
N
F0038 I
Cl
Cl
OH
D1736 Cl
Br
I
OH
D0412
C0645 Cl
N
N OH
D0208
C0187 Br
Cl
Quinolines
5g 1g 1g 25g 5g 25g 1g 5g 25g 5g
7-Bromo-5-chloro-8-hydroxyquinoline 5-Bromo-8-hydroxyquinoline 5-Chloro-8-hydroxy-7-iodoquinoline 5-Chloro-8-hydroxyquinoline 5,7-Dibromo-8-hydroxyquinoline 5,7-Dichloro-8-hydroxyquinoline
Unit Size 5g 25g 25g 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 25g 250g 250g 25g 25g
221
Electroluminescence
Product No. Product Name D1736 F0038 P0531 M0420 H0305
Unit Size
5,7-Diiodo-8-hydroxyquinoline 5-Fluoro-8-quinolinol 8-Hydroxy-7-propylquinoline 8-Hydroxyquinaldine 8-Quinolinol
25g 25g
B3464
B0093
B2893
B3441
S
S
Thiophenes
B3363
B1276
N
tBu
N
O
S
CH3
O
O B
CH3
O
O
S
S
S
S
S
S
S
B1067
S
CH3
B2862
CH3
O
S
B2827
Br
Br Br
B2302
S
B(OH)2
B1458
S
Br S
C H
O
C H
C2324
(CH2)3CH3
Br
O
C1801
Br
B3386
O S
S
S
Br
S
Br
Br
CH3
B2934
Br
B0941
S
O S
S
CH3
Br
B3226
B
Cl
B1540
Br
CH3 CH3
C H
CH3
B3200
Br
S
(CH2)5CH3
S
B3385
S
B1025
Br
Br
Br
B3507
Cl
CH3
O
CH3 CH3
Br
B1541
B1996
CH3
O
B3525
S
B1874
B
CH3
B2013
B(OH)2
CH3
CH3 tBu
S
S
S
B1554
25g 5g 5g 500g 500g
1g
S
C OH
S
Cl
C0807
CH3
O Br
S
C OH
C1192
S
S
C2066
Cl
C1722
CH3
S
Cl
C1230
D2098
(CH2)9CH3
Cl O
O S
222
Cl
S
B(OH)2
Cl
S
C H
Cl
S
C OH
S
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Electroluminescence
D2378
D3798
D2474 D0148
D2755
D2245
Br H2N
Br
NH2
. 2HCl
S
Br
S
S
Br
S
S
S
Br
S
Br
D3799
Br
D3800
S
S
Br
S
D3896
S
S
Br
D1548
D3678
(CH2)5CH3
S
Br
D1549
Br
S
D3679
Br
S
S S
Br
D1676
Br
D3928
Br
Br
S
D2611
CH3(CH2)5 Br S
Br Br
Br
S
Br S
S
Br
I
S
S
I
CH3(CH2)5
D2223
D1591
CH3
D3526
D3177
CH3
D3641
S
S
S CH3
S
D3823
S
CH3
D2016
(CH2)11CH3 S
B(OH)2
E0537
S
E0741
S S
S
E0380
O
E0378
CH2CH3
O S
S
CH2CH3
S
S
F0548
S
F0549
H0722
H1298 CH3(CH2)5
O CH3CH2
C H
S
(CH2)6CH3
O
O H C
S
S
B(OH)2
H C
S
CH3
O
CH3
B(OH)2
CH3
H1294
H0756
CH3 CH3
(CH2)5CH3
O B
CH3
I0374
O
S
M0899
I
M0911
S
S
M1850
S
CH3 O
CH3
O
H S
C H
CH3
M1459
CH3
CH3 S
CH3
I
S
M0440
S
M0635
(CH2)5CH3
S
CH3
I0380
B O
S
O CH3
S
B(OH)2
S
C OH
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
223
Electroluminescence
M1118
N0533
O0245
O0213
(CH2)8CH3 CH3
P1835
(CH2)17CH3
(CH2)7CH3
OH
S
S
O
P1127
S
P1397
S
S
P1126
P1128
(CH2)4CH3
B3561
(CH2)4CH3
CH2CH2CH3 S
S
S
S
N
S
T2699
T1149
T2518
Br S
S
T1084
CH3
Br Br
T0218
Br
Br
CH3
O
O
Br
S
Br
CH3
C OH
O
B
S
O
S
S
C OH S
CH3
Br
T2729
T2513
T2621
T0725
T0864 O
S
S
C H
O S
S
S
S
T0223
T1772
S
B(OH)2
T1975
C H S
T2388
T2347 O C H
B(OH)2
O S
S
B(OH)2
S
S
C H
HO C
O S
C OH
O
T0956
U0056
(CH2)10CH3
Br Br
S
Br
S
Product No. Product Name B3464 B0093 B2893 B3441 B1554 B3363 B1276 B1874 B1996 B2013 B3525 B3507 B1025 B1540
224
Benzo[1,2-b:4,5-b ']dithiophene Benzo[b]thiophene Benzo[b]thiophene-2-ylboronic Acid (contains varying amounts of Anhydride) 2,5-Bis(4-biphenylyl)thiophene 2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene 5,5'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2'-bithiophene 2,2'-Bithiophene 5-Bromo-2,2'-bithiophene-5'-carboxaldehyde 2-Bromo-5-chlorothiophene 3-Bromo-2-chlorothiophene 2-Bromodibenzothiophene 2-Bromo-3-hexylthiophene 2-Bromo-3-methylthiophene 2-Bromo-5-methylthiophene (stabilized with Copper chip + NaHCO3)
Unit Size 1g
1g
1g 5g 5g 1g 5g 10g 1g 5g 5g
5g 5g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
5g 25g 25g 5g 25g 5g 25g 5g 25g 25g 5g 5g 25g 25g
Electroluminescence
Product No. Product Name B1541 B3385 B3200 B3226 B0941 B1067 B2862 B2934 B2827 B3386 B2302 B1458 C1801 C2324 C0807 C1192 C2066 C1722 C1230 D2098 D2378 D2474 D0148 D3798 D2755 D2245 D3799 D3800 D3896 D3678 D3679 D1548 D1549 D1676 D3928 D2611 D2223 D1591 D3526 D3177 D3641 D3823 D2016 E0741 E0380 E0378 E0537 F0548 F0549 H0722 H1298 H1294 H0756 I0374 I0380 M0635 M0440 M0899 M0911 M1850 M1459 M1118 N0533 O0245 O0213 P1835 P1127 P1397
3-Bromo-4-methylthiophene 4-Bromo-2-methylthiophene 5-Bromo-5'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2'-bithiophene 3-Bromothieno[3,2-b]thiophene 2-Bromothiophene 3-Bromothiophene 5-Bromo-2-thiopheneboronic Acid (contains varying amounts of Anhydride) 3-Bromothiophene-2-carboxaldehyde 4-Bromothiophene-2-carboxaldehyde 4-Bromo-2-thiophenecarboxylic Acid 5-Bromo-2-thiophenecarboxylic Acid 3-Butylthiophene 2-Chloro-3-methylthiophene 2-Chloro-5-methylthiophene 2-Chlorothiophene 3-Chlorothiophene 5-Chloro-2-thiopheneboronic Acid (contains varying amounts of Anhydride) 5-Chlorothiophene-2-carboxaldehyde 5-Chlorothiophene-2-carboxylic Acid 3-Decylthiophene 3,4-Diaminothiophene Dihydrochloride Dibenzothiophene Dibenzothiophene 3,3'-Dibromo-2,2'-bithiophene 5,5'-Dibromo-2,2'-bithiophene 2,8-Dibromodibenzothiophene 2,6-Dibromodithieno[3,2-b:2',3'-d]thiophene 3,5-Dibromodithieno[3,2-b:2',3'-d]thiophene 2,5-Dibromo-3-hexylthiophene 2,5-Dibromothieno[3,2-b]thiophene 3,6-Dibromothieno[3,2-b]thiophene 2,3-Dibromothiophene 2,5-Dibromothiophene 3,4-Dibromothiophene 3,4'-Dihexyl-2,2'-bithiophene 2,5-Diiodothiophene 2,8-Dimethyldibenzothiophene 2,5-Dimethylthiophene 2,7-Diphenyl[1]benzothieno[3,2-b][1]benzothiophene 2,5-Diphenylthiophene Dithieno[3,2-b:2',3'-d]thiophene Dithieno[3,2-b:2',3'-d]thiophene-2-boronic Acid (contains varying amounts of Anhydride) 3-Dodecylthiophene 3,4-Ethylenedioxythiophene 2-Ethylthiophene 3-Ethylthiophene 5-Ethylthiophene-2-carboxaldehyde 5'-Formyl-2,2'-bithiophene-5-boronic Acid (contains varying amounts of Anhydride) 5-Formyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride) 3-Heptylthiophene 3-Hexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene 4-Hexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene 3-Hexylthiophene 2-Iodothiophene 3-Iodothiophene 2-Methylthiophene 3-Methylthiophene 3-Methylthiophene-2-aldehyde 5-Methylthiophene-2-aldehyde 5-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride) 3-Methyl-2-thiophenecarboxylic Acid 5-Methyl-2-thiophenecarboxylic Acid 3-Nonylthiophene 3-Octadecylthiophene 3-n-Octylthiophene 2-Pentylthiophene 3-Pentylthiophene 2-Phenylthiophene
Unit Size 5g 5g 200mg 25g 25g 1g 1g 5g 5g 5g 1g 1g 5g 5g 5g 1g 1g 5g 1g 100mg 25g 5g 1g 1g 1g 200mg 200mg 200mg
1g 200mg 5g 5g 1g 5g 5ml
200mg 200mg 1g 5g 5g 5ml 1g 1g 1g 1g 1g
5g 25g 1g 25ml 25g 25g 1g 5g
1g
1g 1g 5g 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 25g 1g 1g 250g 250g 5g 25g 25g 25g 5g 5g 25g 25g 25g 25g 5g 5g 25g 5g 1g 250g 25g 5g 5g 5g 1g 1g 5g 5g 1g 25g 25g 25g 5g 25g 100mg 25ml 100mg 100mg 1g 1g 25g 25g 25ml 25ml 5g 1g 5g 5g 5g 5g 25g 250g 5g 500ml 500g 500g 10g 5g 25g 5g 5g 5g 25g 5g 5g 5g
225
Electroluminescence
Product No. Product Name P1126 P1128 B3561 T2699 T1149 T2518 T0218 T1084 T2729 T2513 T2621 T0725 T0864 T0223 T1772 T1975 T2388 T2347 T0956 U0056
Unit Size
3-Phenylthiophene 3-Propylthiophene 2-(2-Pyridyl)benzo[b]thiophene 3,3',5,5'-Tetrabromo-2,2'-bithiophene Tetrabromothiophene 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2'-bithiophene 2-Thenoic Acid 3-Thenoic Acid Thieno[2,3-b]thiophene Thieno[3,2-b]thiophene Thieno[3,2-b]thiophene-2-boronic Acid (contains varying amounts of Anhydride) 2-Thiophenaldehyde (stabilized with HQ) 3-Thiophenaldehyde Thiophene 2-Thiopheneboronic Acid (contains varying amounts of Anhydride) 3-Thiopheneboronic Acid (contains varying amounts of Anhydride) 2,3-Thiophenedicarboxaldehyde 2,5-Thiophenedicarboxylic Acid 2,3,5-Tribromothiophene 3-Undecylthiophene
B1336
CH3
CH3
Triphenylamines
N
N
N
5g 5g 5g 5g 25g 5g 250g 25g 5g 5g 1g 500ml 25g 500ml 25g 5g 5g 25g 250g 5g
B2843 CH3
N
N N
CH3
CH3
25ml 5g 25ml 5g 1g 1g 5g 25g 1g
1g
CH3 CH3
CH3 CH3
N
1g 5g 1g 25g 5g 1g 1g
B2269
B2079 B3146
Cl
1g 1g
CH3 CH3
CH3
N O
O
H C
C H
Cl
B2305
B3089
B2844
B2633
D3302
Br N
Br
N N
Br
N
CH3
D3303
Br
CH3
D1910
Br
N
N
N
D2347
Br
Br N
N
D2172
D3739 O
CH3
CH3
Br
C H
N
N N
Br
D3537 B(OH)2
D2737
D2448 D3236
I0490
I0776
O
I
C H CH3 N
I
N
N
CH3
N CH3
N0831 CH3
T2269 NO2
T1812
CH3
OCH3
CH3O
CH3
CH3
M1898
N
N
T2616
CH3 N
N
N
N
N
N N
CH3
226
N
N
N
CH3
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Electroluminescence
T0507
T2332
T1361
T2310
T1724
Br
NH2
I
O C H
N
N
N
H2N
T2333
O2N
NH2
Br
N
N O
Br
O
H C
C H
I
T2558 NO2
CH3
N
N NO2
CH3
CH3
Product No. Product Name B1336 B2079 B3146 B2269 B2843 B2305 B3089 B2844 B2633 D3302 D3303 D1910 D2347 D2172 D3739 D3537 D2448 D3236 D2737 I0490 I0776 M1898 N0831 T2269 T1812 T2616 T0507 T2332 T1361 T2310 T1724 T2333 T2558
I
Unit Size
N,N '-Bis(4-chlorophenyl)-N,N '-diphenyl-1,4-phenylenediamine 1,1-Bis[4-[N,N-di(p-tolyl)amino]phenyl]cyclohexane 1,1-Bis[4-[N,N-di(p-tolyl)amino]phenyl]cyclohexane (purified by sublimation) 4,4'-Bis[di(3,5-xylyl)amino]-4''-phenyltriphenylamine Bis(4-formylphenyl)phenylamine 4,4'-Bis[N-(1-naphthyl)-N-phenylamino]-4''-phenyltriphenylamine 4-Bromo-4',4''-dimethyltriphenylamine 4-Bromo-4'-(diphenylamino)biphenyl 4-Bromotriphenylamine 4,4'-Dibromo-4''-cyclohexyltriphenylamine 4,4'-Dibromo-4''-phenyltriphenylamine 4,4'-Dibromotriphenylamine 4,4'-Dimethyltriphenylamine 4-(N,N-Diphenylamino)benzaldehyde 3-(Diphenylamino)dibenzo[g,p]chrysene 4-(Diphenylamino)phenylboronic Acid (contains varying amounts of Anhydride) N,N '-Diphenyl-N,N '-di(m-tolyl)benzidine N,N '-Diphenyl-N,N '-di(m-tolyl)benzidine (purified by sublimation) 4-(Di-p-tolylamino)benzaldehyde N-(4'-Iodobiphenyl-4-yl)-N-(m-tolyl)aniline 4-Iodo-4',4''-dimethoxytriphenylamine 4-Methyltriphenylamine 4-Nitrotriphenylamine N,N,N ',N '-Tetrakis(p-tolyl)benzidine N,N,N ',N '-Tetraphenylbenzidine 4,4',4''-Tri-9-carbazolyltriphenylamine Triphenylamine Tris(4-aminophenyl)amine Tris(4-bromophenyl)amine Tris(4-formylphenyl)amine Tris(4-iodophenyl)amine Tris(4-nitrophenyl)amine Tri-p-tolylamine
B0482
CH3
Diphenylamines
CH3
N
B2429
NH
N
CH3 CH3
1g 100mg
250mg 5g
1g
5g 5g
1g 1g 1g
1g
5g 1g 25g 1g
5g 1g 5g
B2684
B2803
CH3
CH3 NH
Br
1g 5g 1g 1g 1g 100mg 1g 1g 25g 1g 1g 100mg 25g 25g 200mg 1g 5g 5g 5g 1g 1g 5g 1g 5g 25g 5g 250g 5g 25g 500mg 25g 25g 25g
NH
Br
CH3 C
NH
CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
C CH3 CH3
227
Electroluminescence
B2685
B2960
C0711
D2952
D0632
Cl I
NH
CH3CH2
I O2N
D3398
NH
NO2
D3845
N
NH
D2986
NH
NH
CH3
D0812
NH
NH
NH
M1135
NH
NH
D1512
D0609 D0906
NH
D3567
OCH3
NH
D2987
D0950
CH3 NH
CH3O
CH3
D0878
NH
N N
D2988
CH3
CH3
CH
CH3CH2
NH
H N
CH3
NH
M2069
NH
CH3
NH
M1258
CH3
M1173 CH3
OCH3 NH
NH
OCH3
NH
NH
CH3
NH
CH3
CH3
CH3
P1497
P1498
P0197
P0198
NH
T2201
NH NH
T2065
NH
T1831 NH
NH
CH3 HN
NH
Product No. Product Name B0482 B2429 B2684 B2803 B2685 B2960 C0711 D2952 D0632 D3398 D3845 D2986 D2988 D2987
228
Bindschedler's Green Leuco Base Bis(4-biphenylyl)amine Bis(4-bromophenyl)amine Bis(4-tert-butylphenyl)amine Bis(4-iodophenyl)amine Bis(4-nitrophenyl)amine 3-Chlorodiphenylamine 4-(Diethylamino)benzaldehyde Diphenylhydrazone 4,4'-Dimethoxydiphenylamine 2,4-Dimethyldiphenylamine 3,4-Dimethyldiphenylamine 1,1'-Dinaphthylamine 1,2'-Dinaphthylamine 2,2'-Dinaphthylamine
Unit Size 1g 1g 1g 25g 1g
1g 25g
1g
5g 5g 5g 500g 5g 1g 5ml 1g 5g 500g 25g 1g 5g 1g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Electroluminescence
Product No. Product Name
Unit Size
N,N '-Di-2-naphthyl-1,4-phenylenediamine N,N '-Diphenylbenzidine N,N '-Diphenyl-1,4-phenylenediamine N,N '-Diphenyl-1,4-phenylenediamine m,m '-Ditolylamine p,p '-Ditolylamine N,N '-Di-p-tolylbenzidine 3-Methoxydiphenylamine 4-Methoxydiphenylamine 3-Methyldiphenylamine 4-Methyldiphenylamine N-Phenyl-3-biphenylamine N-Phenyl-4-biphenylamine N-Phenyl-1-naphthylamine N-Phenyl-2-naphthylamine N-(p-Tolyl)-1-naphthylamine N-(p-Tolyl)-2-naphthylamine N,N ',N ''-Triphenyl-1,3,5-benzenetriamine
D0812 D0878 D0609 D0906 D1512 D0950 D3567 M1135 M2069 M1258 M1173 P1497 P1498 P0197 P0198 T2201 T2065 T1831
B2169
25g 5g 25g 25g 5g 5g 1g 25g 5g 1g
25g 25g
5g
B1066 N
N
D2757
B1767 B2696 N
N
N
N
N O
Oxazoles & Oxadiazoles D1429
O
t
NH2
Bu
NEt2
Et2N
H0291 N
N
N
O
OH
O
Product No. Product Name B2169 B1066 B1767 B2696 D2757 D1429 H0291
N O
O
H2N
500g 25g 500g 500g 25g 25g 5g 500g 25g 25g 5g 500mg 500mg 500g 500g 500mg 500mg 25g
Unit Size
2,5-Bis(4-aminophenyl)-1,3,4-oxadiazole 2,5-Bis(4-diethylaminophenyl)-1,3,4-oxadiazole 2-(4-tert-Butylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole 2-(4-tert-Butylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole (purified by sublimation) 2,5-Di(1-naphthyl)-1,3,4-oxadiazole 2,5-Diphenyl-1,3,4-oxadiazole 2-(2-Hydroxyphenyl)benzoxazole
B3573
D3842 CH3
Thiazoles & Thiadiazoles
CH3 CH3 CH3 O O B
N O CH3
B
5g 1g
1g
5g 25g 25g 5g 5g 10g 25g
H0973 Br N
OH
N
N S
N
O
CH3 CH3 CH3
1g
S
S
Br
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
229
Electroluminescence
Product No. Product Name B3573 D3842 H0973
Unit Size
4,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,1,3-benzothiadiazole 4,7-Dibromo-2,1,3-benzothiadiazole 2-(2-Hydroxyphenyl)benzothiazole
B0987
A1340
1g
B2489
5g 5g
B2294
NH2
B(OH)2 B(OH)2
NH2
-Phenyls
B2490
B3019
B3151
B1711
(HO)2B
O
CH3
B
B(OH)2
CH3
CH3
O
O B O
O
CH3
O
CH3
B
H2N
Br NH2
CF3
CH3
B2001
B0559 F3C
CH3 CH3
1g 25g 25g
B1330
B3648
B2155
D3390
Br Br
D1344
I
D3372
CH3O
Br
D2315
Br
D2759 CH3
OCH3
H2N
NH2
D3394
Br
Br
I0785
I
I
N0193
I
H2N
NH2
D3534 CH3 I
N0610
I
I
Q0001
NO2 O2N
I
NO2
Q0018
S0220
NO2
T0020
T2412
T1023 CH3
B(OH)2 H2N 3
CH3 NH2
4
CH3
CH3
T0253 CH3 H2N
230
CH3 NH2
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Electroluminescence
Product No. Product Name B0987 A1340 B2489 B2294 B2490 B3019 B3151 B1711 B0559 B2001 B1330 B3648 B2155 D3390 D1344 D3372 D2315 D2759 D3534 D3394 I0785 N0193 N0610 Q0001 Q0018 S0220 T0020 T2412 T1023 T0253
Unit Size
3-Aminobiphenyl 4-Amino-p-terphenyl 3-Biphenylboronic Acid (contains varying amounts of Anhydride) 4-Biphenylboronic Acid (contains varying amounts of Anhydride) 4,4'-Biphenyldiboronic Acid 2-(4-Biphenylyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 4,4'-Bis(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)biphenyl 2,2'-Bis(trifluoromethyl)benzidine 2-Bromobiphenyl 3-Bromobiphenyl 4-Bromobiphenyl 4-Bromo-4'-iodobiphenyl 4-Bromo-p-terphenyl 4,4''-Diamino-p-terphenyl o-Dianisidine 4,4''-Dibromo-p-terphenyl 4,4'-Diiodobiphenyl 4,4'-Diiodo-3,3'-dimethylbiphenyl 4,4''-Diiodo-p-terphenyl 4,4''-Dinitro-p-terphenyl 4-Iodobiphenyl 3-Nitrodiphenyl 4-Nitro-p-terphenyl p-Quaterphenyl p-Quinquephenyl p-Sexiphenyl p-Terphenyl 2-p-Terphenylboronic Acid (contains varying amounts of Anhydride) 3,3',5,5'-Tetramethylbenzidine o-Tolidine
B2111
Coumarins
N
O
5g 1g 1g 1g 5g 100mg 100mg 25g 1g
5g 25g
S
O
Et2N
O
O
Product No. Product Name
Unit Size
3-(2-Benzimidazolyl)-7-(diethylamino)coumarin 3-(2-Benzothiazolyl)-7-(diethylamino)coumarin
1g 1g
Q0057 Q0083
D2687 D3227 CH3
O
N
Quinacridones
H N
N O
CH3
O
Product No. Product Name D2687 D3227 Q0057 Q0083
5g 5ml 5g 25g 5g 1g 1g 25g 1g 25g 5g 1g
25g 25g 25g 25g 1g 5g 1g 25g 25ml 25g 250g 25g 5g 5g 500g 5g 250g 25g 5g 1g 25g 25g 5g 25g 1g 1g 500g 1g 25g 500g
N N H
CH2CH3
B2111 B2088
1g
5g 5g 5g 5g
B2088 N
CH3CH2
1g 1g
N,N '-Dimethylquinacridone N,N '-Dimethylquinacridone (refined product of D2687) Quinacridone Quinacridone (purified by sublimation)
O
N H
Unit Size 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 1g 25g 1g
231
Electroluminescence
P0972
P0078 P1629
Perylenes
P0984
O
O
O
O HN
O
O
O
O
O NH O
Product No. Product Name P0078 P1629 P0972 P0984
Unit Size
Perylene Perylene (refined product of P0078) 3,4,9,10-Perylenetetracarboxylic Dianhydride 3,4,9,10-Perylenetetracarboxylic Diimide
A0632
5g 25g
A2180
B1495
25g 1g 500g 25g
B2807 Br
NH2
Pyrenes NH2
D2167
D2160
D2168
N0419
NH2
NH2
Br
N0838
NH2
NO2
H2N
NH2
NO2 NH2
P1104
P1625 B(OH)2
Product No. Product Name A0632 A2180 B1495 B2807 D2167 D2160 D2168 N0419 N0838 P1104 P1625
Unit Size
1-Aminopyrene 4-Aminopyrene 1-Bromopyrene 4-Bromopyrene 1,3-Diaminopyrene 1,6-Diaminopyrene 1,8-Diaminopyrene 1-Nitropyrene 4-Nitropyrene Pyrene 1-Pyreneboronic Acid (contains varying amounts of Anhydride)
A2051
B2804
I
I
O
232
5g
1g
25g 5g
25g 1g 25g 5g 100mg 100mg 100mg 25g 1g 500g 25g
B2713
O
O
H C
C H
N C CH3
5g 5g 1g
B2805 O C H
Carbazoles
1g
N
N
N
CH2
CH2
N
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Electroluminescence
B3458
B3459
C0032
D2116
Br
Br
H2N
N
N H
N H
CH2CH3
D2983
D2982 Br
D2981
Br
D3952 H3C
C CH3 CH3
N
N H
CH2CH3
E0571
M0960
Br
CH3
H3C
N
N H
E0071 E0247
H3C C
N
E0359
Br
Br
Br
N H
NH2 N H
Br Br
D3932
CH2CH3
P1492
T1934
O N
C H CH
N
N N
N
N
N
CH2CH3
CH2CH3
T2700
N
N
CH3
T2616
V0021 N
N N N
N N
N
N N
N N
CH
CH2
Product No. Product Name A2051 B2804 B2805 B2713 B3458 B3459 C0032 D2116 D3932 D2983 D2982 D2981 D3952 E0071 E0247 E0359 E0571 M0960 P1492 T1934 T2700 T2616 V0021
Unit Size
9-Acetyl-3,6-diiodocarbazole 9-Benzylcarbazole-3-carboxaldehyde 9-Benzylcarbazole-3,6-dicarboxaldehyde 4,4'-Bis(9H-carbazol-9-yl)biphenyl 3-Bromocarbazole 3-Bromo-9-ethylcarbazole Carbazole 3,6-Diaminocarbazole 2,7-Dibromocarbazole 3,6-Dibromocarbazole 3,6-Dibromo-9-ethylcarbazole 3,6-Dibromo-9-phenylcarbazole 3,6-Di-tert-butylcarbazole 9-Ethylcarbazole 9-Ethylcarbazole N-Ethylcarbazole-3-carboxaldehyde 9-Ethylcarbazole-3-carboxaldehyde Diphenylhydrazone 9-Methylcarbazole 9-Phenylcarbazole 1,3,5-Tri(9H-carbazol-9-yl)benzene (purified by sublimation) 2,4,6-Tri(9H-carbazol-9-yl)-1,3,5-triazine 4,4',4''-Tri-9-carbazolyltriphenylamine 9-Vinylcarbazole A0621
Fluorenes & Fluorenones
A1040
NH2
1g 1g 1g
1g
1g 25g 1g 1g 5g 1g 1g 25g
1g
5g 5g 1g 1g 1g
5g 5g 100mg 5g 5g 5g 500g 5g 5g 25g 5g 5g 1g 500g 25g 25g 1g 25g 25g 5g 5g 5g 25g
B1715
B1549 B2654
NH2 O HO H2N
OH
NH2
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
233
Electroluminescence
B3069
B1046
B3109
B3560
D0092
Br Br
Br
D3933
D3859
Br CH3(CH2)5
Br (CH2)5CH3
D3872
Br
D3934
CH3
H2N
O
Br
Br
CH3
D0834
D3556
Br CH3(CH2)7
Br (CH2)7CH3
F0061
NH2
D3557
Br
Br
F0333
Br
Br O
F0229
Br O Br
F0021
O2N
NO2
F0590
C H
F0263
H0329
OH
N0201
O O
O
S0800
T2597
B(OH)2
Br
Br
Br
Br
Product No. Product Name A0621 A1040 B1549 B2654 B1715 B3069 B1046 B3109 B3560 D0092 D3933 D3859 D3934 D3556 D3557 D3872 D0834 F0061 F0333 F0229 F0021 F0590 F0263 H0329
234
NO2
O
O
O
S0831
OH
C OH
C OH
2-Aminofluorene 2-Amino-9-fluorenone 9,9-Bis(4-aminophenyl)fluorene 9,9-Bis(4-aminophenyl)fluorene (purified by sublimation) 9,9-Bis(4-hydroxyphenyl)fluorene 2-Bromofluorene 9-Bromofluorene 2-Bromo-9-fluorenone 2-Bromo-9,9'-spirobi[9H-fluorene] 2,7-Diaminofluorene 2,7-Dibromo-9,9-dihexylfluorene 2,7-Dibromo-9,9-dimethylfluorene 2,7-Dibromo-9,9-di-n-octylfluorene 2,7-Dibromofluorene 2,7-Dibromo-9-fluorenone 2,2'-Dibromo-9,9'-spirobi[9H-fluorene] 2,7-Dinitrofluorene Fluorene Zone Refined (number of passes:70) 2-Fluorenecarboxaldehyde 9-Fluorenol 9-Fluorenone 9-Fluorenone-1-carboxylic Acid 9-Fluorenone-2-carboxylic Acid 2-Hydroxy-9-fluorenone
Unit Size 5g 1g
5g
5g
25g 5g 25g 1g 25g 500g 25g 100g 25g 5g 25g 5g 5g 25g 5g 25g 5g 25g 5g 25g 25g 100g 5g 25g 1g 5g 25g 1sample 5g 25g 250g 25g 500g 1g 5g 10g 1g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Electroluminescence
Product No. Product Name N0201 S0800 S0831 T2597
Unit Size
2-Nitrofluorene 9,9'-Spirobi[9H-fluorene] 9,9'-Spirobi[9H-fluorene]-2-boronic Acid 2,2',7,7'-Tetrabromo-9,9'-spirobi[9H-fluorene]
A1709
25g 5g 5g 5g
1g 1g 1g
A1687
A0495 A0992 A0405
NH2
A1843
NH2
B(OH)2
Anthracenes
B2801
P1137 O CH2 P
CH2 P O
OCH2CH3
B2615
B2616
C C
B2871 B0872
Br
OCH2CH3
Br
Br
OCH2CH3
C C
OCH2CH3
B3442
C1962
D3183
D3171
D0166
Br
Br Br
Cl
Br
Br Br
D0327
D1689
P0138
Br
P1494
P1495
Ph
Cl
NH NH
Cl
Ph
P1496 NH
Product No. Product Name A1709 A1687 A0495 A0992 A0405 A1843 B2801 P1137 B2615 B2616 B2871 B0872 B3442 C1962
1-Aminoanthracene 2-Aminoanthracene Anthracene Anthracene Anthracene Zone Refined (number of passes:30) 2-Anthraceneboronic Acid (contains varying amounts of Anhydride) 9,10-Bis(diethylphosphonomethyl)anthracene 9,10-Bis(phenylethynyl)anthracene 1-Bromoanthracene 2-Bromoanthracene 9-Bromoanthracene 9-Bromoanthracene 2-Bromo-9,10-diphenylanthracene 2-Chloroanthracene
Unit Size 1g 1g 25g 500g 25g 500g 1sample 250mg 1g 1g 1g 10g 500mg 1g 1g 5g 5g 25g 100g 5g 25g 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
235
Electroluminescence
Product No. Product Name D3183 D3171 D0166 D0327 D1689 P0138 P1494 P1495 P1496
Unit Size
1,5-Dibromoanthracene 2,6-Dibromoanthracene 9,10-Dibromoanthracene 9,10-Dichloroanthracene 9,10-Diphenylanthracene 9-Phenylanthracene N-Phenyl-1-anthramine N-Phenyl-2-anthramine N-Phenyl-9-anthramine
B0618
1g 1g 500g 10g 25g 5g 500mg 1g 5g
25g 1g 1g 1g
1g
B0619
D2359
D3624 Br
Br
Br
Br
Br
Naphthalenes Br
I0266
N0630 I
N0649
N0052
B(OH)2
NH2
B(OH)2
Product No. Product Name B0618 B0619 D2359 D3624 I0266 N0630 N0649 N0052 N0212
N0212 NO2
Unit Size
1-Bromonaphthalene 2-Bromonaphthalene 1,4-Dibromonaphthalene 2,7-Dibromonaphthalene 1-Iodonaphthalene 1-Naphthaleneboronic Acid (contains varying amounts of Anhydride) 2-Naphthaleneboronic Acid (contains varying amounts of Anhydride) 1-Naphthylamine 1-Nitronaphthalene
25g 5g 5g 5g 1g 1g
5g 5g 25g
B0017
B2982
B2983
C0339
B3562
B1603
C1961 C0386
C1689
500g 25g 25g 25g 25g 25g 25g 25g 500g
Polycyclic Aromatic Hydrocarbons (PAHs) B0085
C C Si[CH(CH3)2]3
C C Si[CH(CH3)2]3
Br
236
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Electroluminescence
D0145
B0403
D0677
I0222
D1005
D3736
D1311
M0248
M1411
N0001
O
CH3
CH3
N0599
CH3
O
P0030
P1893
Product No. Product Name B0017 B2982 B2983 C0339 B0085 B3562 B1603 C1961 C0386 C1689 D0145 B0403 D1005 D3736 D1311 D0677 I0222 M0248 M1411 N0001 N0599 P0030 P1893 T0561 T2233 T0513
Benz[a]anthracene Benzo[b]fluoranthene Benzo[ghi]perylene Benzo[a]phenanthrene 3,4-Benzopyrene 6,13-Bis(triisopropylsilylethynyl)pentacene 7-Bromobenz[a]anthracene Coronene (refined product of C0386) Coronene 1H-Cyclopenta[l]phenanthrene Dibenz[a,h]anthracene Dibenzo[a,c]anthracene Dibenzo[b,def]chrysene Dibenzo[g,p]chrysene 1,2:8,9-Dibenzopentacene 7,12-Dimethylbenz[a]anthracene Isoviolanthrone 7-Methylbenz[a]anthracene 2-Methylcyclopenta[l]phenanthrene Naphthacene Naphtho[2,3-a]pyrene Pentacene (purified by sublimation) Picene (purified by sublimation) 5,6,11,12-Tetraphenylnaphthacene 5,6,11,12-Tetraphenylnaphthacene (refined product of T0561) Triphenylene
CH3
T0513
T0561 T2233 Ph
Ph
Ph
Ph
Unit Size 1g
5g
100mg 1g 1g 100mg
200mg 1g
100mg
100mg 1g 100mg 100mg 100mg 250mg 100mg
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 100mg 100mg 1g 1g 100mg 5g 100mg 5g 1g 100mg 100mg 100mg 1g 100mg 5g 10g 100mg 1g 5g 100mg 1g 1g 1g 1g 1g
237
Electroluminescence
B0054
B3088
B2076
C1719
H2N
N
Others
NH2
N
NHCH2
N H
C0130
N H
C0248
C0460
F0011
Cl
I0429 O
O
Cl
Cl
H N
N
Cl N
N H
S
Cl
N
N N
O
NH
T0337
O
Cl O
J0007
HN
N
N0659
O
P1047
P1136 P0080
NH2 N
N
N
CH3CH2
H2N
P0082
N N
NH2
P0106
O
NH
N
N HN
S
Product No. Product Name B0054 B3088 B2076 C1719 C0130 C0248 C0460 F0011 I0429 J0007 T0337 N0659 P1136 P0080 P1047 P0082 P0106 T1358
O O
T1358
N
N
O
CH2CH3
H N
N
N
Unit Size
Benzimidazole N-Benzyl-2-naphthylamine 1,1-Bis(4-aminophenyl)cyclohexane 2-Chlorobenzimidazole 5-Chlorobenzimidazole 2-Chlorophenothiazine Cyanuric Chloride Flavanthrone Indanthrone Julolidine Melamine Monomer Nile Red 9,10-Phenanthrenequinone 9,10-Phenanthrenequinone Phenanthridine Phenazine Phenothiazine meso-Tetraphenylchlorin
25g 5g 5g 5g 25g 25g 1g 5g 25g 500mg 25g 5g 1g
5g 25g
500g 25g 25g 5g 25g 500g 500g 5g 25g 25g 500g 1g 250g 25g 10g 25g 500g 100mg
Purification just before use is recommended.
Phthalocyanines (see p.273) Reagents for Conducting Polymer Research (see p.210) Dichlorosilanes (for Polysilanes) (see p.292)
238
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Electroluminescence
References 1987, C. W. Tang, S. A. Van Slyke, , 913. 1990, C. Adachi, T. Tsutsui, S. Saito, , 799. 2001, S. Seki, S. Miyashita, , 70. 2001, J. Kido, , 333. 2001, K. Hachise, N. Takada., N. Tanigaki, , 455. 1998, M. A. Baldo, D. F. O'Brien, Y. You, A. Shoustikov, S. Sibley, M. E. Thompson, S. R. Forrest, , 151. J. H. Burroughes, D. D. C. Bradley, A. R. Brown, R. N. Marks, K. Mackay, R. H. Friend, P. L. Burn, A. B. Holmes, 1990, , 539. 8) R. H. Friend, R. W. Gymer, A. B. Holmes, J. H. Burroughes, R. N. Marks, C. Taliani, D. D. C. Bradley, D. A. Dos Santos, J. 1999, L. Bredas, M. Logdlund, W. R. Salaneck, , 121. 2001, 9) R. H. Friend, , 425. 2007, 10) S.-C. Lo, P. L. Burn, , 1097. 1) 2) 3) 4) 5) 6) 7)
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
239
Reagents for Solar Cell Research
Reagents for Solar Cell Research Photovoltaic power generation has attracted much attention for the mitigation options of climate change and as an alternative energy source. Dye-sensitized solar cells and organic thin-film solar cells are lightweight and have high process ability while maintaining low production costs and have been studied for the next generation of solar cells.
●Dye-Sensitized Solar Cells Grätzel and co-worker reported solar energy-to-electricity conversion efficiencies as high as 7-8% on dye-sensitized fractal-type TiO2 electrodes1). These solar cells, also known as the Grätzel cell, are composed of I) transparent electrode, II) TiO2, III) dyes, IV) electrolytes, V) counter electrode.
Transparent Electrode
Electrolyte
Counter Electrode
Dye
１）Dyes A large numbers of dyes (photosensitizer) have been synthesized to improve the efficiency of solar cells. Ruthenium complex dyes are most widely used for sensitizer. N719 dye (red dye) is a typical Rucomplex dye and a modification of the classical N-3 dye, to increase cell voltage. O
O
HO C
C O N
N 2 (C4H9)4N
SCN Ru NCS N
N
HO C
C O
O
O
N719 Dye
Many ruthenium complex dyes are composed of bipyridine derivatives as ligands. TCI offers a variety of bipyridine derivatives such as 2,2'-bipyridine-4,4'-dicarboxylic acid for ligands, 4,4'-dibromo-2,2'-bipyridyl and 4,4'-bis(chloromethyl)-2,2'-bipyridyl for building blocks in ligand synthesis. TCI also offers custom synthesis to provide chemicals not available in this catalog. Please contact us for a quote. ２）Electrolytes The iodide/triiodide electrolyte is used as a redox mediator between the dyes and the electrode in most dye-sensitized solar cells. Electrolyte solutions such as an acetonitrile solution are effective for achieving high conversion efficiencies. Ionic liquids and gelated electrolytes are also applied for dye-sensitized solar cells because of their advantages of stability and safety.
240
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Reagents for Solar Cell Research
B3514 O
O
HO C
C O N
N 2 (C4H9)4N
SCN Ru NCS
Dye
N
N
HO C
C O
O
O
Product No. Product Name B3514
Unit Size
Bis(tetrabutylammonium) Dihydrogen Bis(isothiocyanato)bis(2,2'-bipyridyl4,4'-dicarboxylato)ruthenium(II) (=N719 Dye)
100mg
D0905
D0711 B2694
B0989 NaO3S
SO3Na
. xH2O
Bipyridyls N
N
N
CH3
B3509
B1077 O
O
HO C
KO
C OH
O
C
C OK
N
B0863
B1876 CH3
B0468
O
CH3
O
HO C
N
N
N
. xH2O
N
N
B0470
N
CH3
B0841 O
N
C OH N
N
N
B3510
N
N
B3511
B3218 Br
N
N N
N
CH2OH
N
N
N
N H
N
CH2OH N
N H
N
B3219
D2913
D3919
D2565 Br
Br
N
N
D3886 (CH2)3CH3
Br
OCH3
OCH3
N
N
N CH3(CH2)3
N
N
N
B0852
H2N
N
N
NH2
B2138 CH3
CH3
N
N
CH3
N0423
CH3
N
CH3
N CH3
. xH2O
N
N
CH3
N
. HCl . H2O
N
SO3Na
NaO3S
N
N
P0081 N
N
B0985
(CH2)8CH3 (CH2)8CH3
P0221
N CH3
D3917
CH3 N
N
N
B0842
N
M0300
N
N CH3
CH3
T0024 N
. H2O
N
. HCl . H2O
N
N
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
N
241
Reagents for Solar Cell Research
T0847 CH3
N N
CH3
CH3 CH3
Product No. Product Name D0711 B2694 D0905 B0989 B3509 B1077 B0841 B1876 B0468 B0863 B0470 B3510 B3511 B3218 B3219 D2913 D3919 D2565 D3886 B0852 B2138 B0842 D3917 B0985 M0300 N0423 P0221 P0081 T0024 T0847
Unit Size
Bathocuproine Bathocuproine (purified by sublimation) Bathophenanthroline Bathophenanthrolinedisulfonic Acid Disodium Salt Hydrate 2,2'-Bicinchoninic Acid 2,2'-Bicinchoninic Acid Dipotassium Salt Hydrate 2,2'-Bi-4-lepidine 2,2'-Bipyridine-4,4'-dicarboxylic Acid 2,2'-Bipyridyl 2,4'-Bipyridyl 2,2'-Biquinoline 2,6-Bis(2-benzimidazolyl)pyridine 4,4'-Bis(hydroxymethyl)-2,2'-bipyridine 4'-(4-Bromophenyl)-2,2':6',2''-terpyridine 4'-Bromo-2,2':6',2''-terpyridine 6,6'-Diamino-2,2'-bipyridyl 4,4'-Dibromo-2,2'-bipyridyl 2,9-Dibutyl-1,10-phenanthroline 4,4'-Dimethoxy-2,2'-bipyridyl 4,4'-Dimethyl-2,2'-bipyridyl 5,5'-Dimethyl-2,2'-bipyridyl 6,6'-Dimethyl-2,2'-bipyridyl 4,4'-Dinonyl-2,2'-bipyridyl Disodium Bathocuproinedisulfonate 5-Methyl-1,10-phenanthroline Neocuproine Hydrochloride 1,10-Phenanthroline Monohydrate 1,10-Phenanthroline Hydrochloride Monohydrate 2,2':6',2''-Terpyridine 3,4,7,8-Tetramethyl-1,10-phenanthroline
1g 1g 1g 1g 1g 100mg 25g 1g 1g 1g 1g 1g 1g 1g 100mg 1g 1g 5g 1g 5g 100mg 1g 1g 100mg 100mg 1g 1g 100mg 1g
B2708
D3903
N
E0556
CH3
N
CH3
N
E0190
E0549
H1286 CH3
I0552
CH2CH2CH3
N
Fe
CH3
I
CH3 CH3
N
I
(CH2)5CH3
M1440
M0253
N P CH(CH3)2 I
I
I
CH2CH3
CH2 N CH3
CH3CH2 N CH2CH2CH3
CH3
N
F0167
CH2CH2CH3
P+ CH2CH3 I -
I
CH3
N
P0242
CH3
T1011
CH2CH3 I
CH2CH2CH3
242
CH3
CH2CH2CH3
E0191
CH3 CH3CH2 N CH3
N
(CH2)3CH3
N
I
I
Electrolytes
5g 1g 5g 5g 5g 5g 100mg 1g 500g 5g 5g 5g 5g 5g 5g 250mg 5g 1g 5g 25g 25g 5g 5g 1g 1g 25g 25g 25g 1g 5g
P CH3
I
N CH2CH3 CH2CH3
(CH2)4CH3
I
CH3(CH2)4 N
(CH2)4CH3 I
(CH2)4CH3
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Reagents for Solar Cell Research
T0057
T0097
(CH2)3CH3
I
CH3CH2 N CH2CH3
(CH2)3CH3
I
CH3(CH2)6 N
T0172
I
I
CH3CH2CH2 N CH2CH2CH3
CH3(CH2)5 N
CH3(CH2)3 P
CH2CH2CH3
CH3
(CH2)3CH3
CH3 N CH3
P0246
CH3
(CH2)3CH3
I CH3(CH2)3
I
CH3
T1564 (CH2)3CH3
I
CH3
(CH2)5CH3 I
(CH2)5CH3
M1455
CH2CH2CH3
P
T0139
(CH2)5CH3
(CH2)6CH3
(CH2)6CH3
CH2CH3
T1450
T1010
(CH2)6CH3
CH2CH3
(CH2)3CH3 CH3(CH2)3 N
T1396
S
N CH3
I (CH2)3CH3
I
CH3
T1056
CH3 CH3
S
I CH3
Product No. Product Name B2708 D3903 E0556 E0190 E0549 E0191 F0167 H1286 I0552 M1440 M0253 P0242 T1011 T0057 T0097 T1396 T1010 T0139 T1450 T0172 M1455 T1564 P0246 T1056
1-Butyl-3-methylimidazolium Iodide 1,2-Dimethyl-3-propylimidazolium Iodide 1-Ethyl-3-methylimidazolium Iodide Ethyltrimethylammonium Iodide Ethyltriphenylphosphonium Iodide Ethyltripropylammonium Iodide (Ferrocenylmethyl)trimethylammonium Iodide 1-Hexyl-2,3-dimethylimidazolium Iodide Isopropyltriphenylphosphonium Iodide 1-Methyl-3-propylimidazolium Iodide Methyltriphenylphosphonium Iodide Phenyltriethylammonium Iodide Tetraamylammonium Iodide Tetrabutylammonium Iodide Tetraethylammonium Iodide Tetraheptylammonium Iodide Tetrahexylammonium Iodide Tetramethylammonium Iodide Tetraphenylphosphonium Iodide Tetrapropylammonium Iodide Tributylmethylphosphonium Iodide Tributylsulfonium Iodide Trimethylphenylammonium Iodide Trimethylsulfonium Iodide
Unit Size 5g 5g 5g 25g
5g 5g 25g 25g 5g 25g 25g
25g
5g 100g 10g 25g
25g 25g
25g 25g 25g 25g 250g 25g 5g 5g 25g 25g 500g 25g 500g 500g 25g 25g 500g 25g 500g 25g 1g 500g 500g
●Organic Thin-film Solar Cells The developments of organic thin film solar cells (organic semiconductor solar cells) have received a tremendous boost over the last decade. There are two typical manufacturing processes, spin-coating and vacuum sublimation. A spin-coating technique involves first the dissolution of the semiconductor materials in an appropriate organic solvent followed by its deposition on the supporting substrate. A vacuum sublimation technique involves depositing insoluble materials under high vacuum to produce a thin-film. These organic thin-film solar cells are lightweight and have high process ability while maintaining low production costs and can be expected to emerge as the next generation of solar cells replacing silicon solar cells which are currently in common use. Currently, TCI is exercising considerable efforts in the development of high purity organic semiconductor materials by employing the sublimation refining technique.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
243
Reagents for Solar Cell Research
C2415
B1641 (CH2)11CH3
CH3 N
n-Type Organic Semiconductors
Organic Semiconducting Materials H1194
M2088
F
F
P0972
F
OCH3
N F
N N
Cu
N N
O
O
O
O
F
F
N F F
O F
O
F F
O
F
N
N
F
T2206
F
F
F
F
F F
S
F
S
F
F
S
4
F
F
Product No. Product Name
Unit Size
C2415 B1641 H1194
C60MC12 Fullerene C60 (pure) 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-Hexadecafluorophthalocyanine Copper(II)
100mg
(purified by sublimation)
100mg
M2088 P0972 T2206
Methyl [6.6]-Phenyl-C61-butyrate 3,4,9,10-Perylenetetracarboxylic Dianhydride Tetradecafluoro-α-sexithiophene (purified by sublimation)
B3441
100mg 1g
1g 100mg 25g 500g 50mg
B1200
B3562
D3526 C C Si[CH(CH3)2]3
S
p-Type Organic Semiconductors N0001
S
S
S
S
S
S
S
S S
S C C Si[CH(CH3)2]3
P0030
P1795
P1893
P1628 N
N NH
N
N
N
N
N N
S0504
T1196
T2269
T1812
CH3
CH3
N
4
S
S
4
S
S
S
N N
N
N
S0220
N Cu
N
HN
N
N
N
S CH3
CH3
T2233
244
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Reagents for Solar Cell Research
Product No. Product Name B3441 B1200 B3562
Unit Size
2,5-Bis(4-biphenylyl)thiophene Bis(ethylenedithio)tetrathiafulvalene 6,13-Bis(triisopropylsilylethynyl)pentacene (This product is unavailable for selling domestically in U.S.) 2,7-Diphenyl[1]benzothieno[3,2-b][1]benzothiophene Naphthacene Pentacene (purified by sublimation) Phthalocyanine (purified by sublimation) Picene (purified by sublimation) Pigment Blue 15 (purified by sublimation) p-Sexiphenyl α-Sexithiophene 2,2':5',2''-Terthiophene (=α-Terthienyl) N,N,N ',N '-Tetrakis(p-tolyl)benzidine N,N,N ',N '-Tetraphenylbenzidine 5,6,11,12-Tetraphenylnaphthacene (refined product of T0561)
D3526 N0001 P0030 P1795 P1893 P1628 S0220 S0504 T1196 T2269 T1812 T2233
B2694
1g 1g
100mg
100mg
5g 5g 100mg 100mg 5g 1g 1g 1g 1g 1g 1g 5g 5g 25g 1g
1g 100mg 100mg 100mg 100mg 1g 5g 250mg
B2695
Others N
N
N
CH3
CH3
N
Product No. Product Name B2694 B2695
Unit Size
Bathocuproine (purified by sublimation) Bathophenanthroline (refined product of D0905)
1g 1g
B1996
B3507
(CH2)5CH3
Thiophenes
Polymer Materials
B3200
B2862
Cl
D2755
Br
O B
CH3
S
O
S
Br
Br
S
B(OH)2
Br
S
S
CH3
D3678
Br
D1549
O S
Br
S
Br
Br
D3896
S
S S
(CH2)5CH3
Br Br
S
Br
E0741
S Br
Br
D3799
CH3 CH3
S
S
O
Br S
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
245
Reagents for Solar Cell Research
Product No. Product Name B1996 B3507 B3200 B2862 D2755 D3799 D3896 D3678 D1549 E0741
Unit Size
2-Bromo-5-chlorothiophene 2-Bromo-3-hexylthiophene 5-Bromo-5'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2'-bithiophene 5-Bromo-2-thiopheneboronic Acid (contains varying amounts of Anhydride) 5,5'-Dibromo-2,2'-bithiophene 2,6-Dibromodithieno[3,2-b:2',3'-d]thiophene 2,5-Dibromo-3-hexylthiophene 2,5-Dibromothieno[3,2-b]thiophene 2,5-Dibromothiophene 3,4-Ethylenedioxythiophene
D3842
D2983
5g
1g 1g 200mg 200mg
1g 5g
D3302
25g 5g 1g 5g 5g 1g 5g 5g 25g 25g
D2982
Br
Br Br
Br
Br
N
Others
N
Br
N
S
N
N H
CH2CH3
Br Br
D2981
D3303
Br
Br
D1910
Br
N
T1361 Br
Br N
N
Br
Br
Br
Br
N Br
Br
Product No. Product Name D3842 D2983 D3302 D2982 D2981 D3303 D1910 T2597 T1361
T2597
Br
Br
Unit Size
4,7-Dibromo-2,1,3-benzothiadiazole 3,6-Dibromocarbazole 4,4'-Dibromo-4''-cyclohexyltriphenylamine 3,6-Dibromo-9-ethylcarbazole 3,6-Dibromo-9-phenylcarbazole 4,4'-Dibromo-4''-phenyltriphenylamine 4,4'-Dibromotriphenylamine 2,2',7,7'-Tetrabromo-9,9'-spirobi[9H-fluorene] Tris(4-bromophenyl)amine
1g 1g
5g 5g
25g 25g 1g 1g 5g 1g 5g 1g 100mg 1g 5g 25g
Reference 1) B. O' Reagan, M. Grätzel,
246
1991,
, 737.
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Photochromic Compounds
Photochromic Compounds Photochromism is the phenomena that of reversible transformation between two forms that have different absorption spectra by photo-irradiation. The history of photochromism dates back to the era of the Alexander the Great. Inspired by Fischer and co-workers who first reported photochromism in spiropyran analogues in 1952, intense studies on photochromic compounds have continued up to the present. The mechanism for photochromism of spiropyran analogues is shown below. CH3 CH3 R N
R
CH3 CH3 hν hν' or Δ
O
N
CH3
O
CH3
Today, research for the application of photochromism is being achieved in a variety of fields including light modulation materials, optical recording materials, optical switches, and photochromic ink. Some of them are being put into practical use. Furthermore, an energetic attempt to introduce photochromic compounds into functional materials for photochemical control is being studied. Especially, diarylethenes 1 and 2 developed by Irie and co-workers are stable at high temperature and have been shown high repeated durability. In addition, various functional molecules can easily be introduced to the aromatic ring of 1 and 2. The solution of 1 changes to red upon irradiation of UV light, but rapidly converts back to colorless by visible light. In this reversible reaction, 1 has been shown a repeated durability over 10,000 times. The crystal of 2 changes to blue upon irradiation of UV light, and returns to colorless by visible light. These changes are rapidly finished within ten pico second. Moreover, the photocyclization quantum yields is limitlessly near to one. Therefore 2 shows extremely effective photochromic reaction. 1 and 2 are ideal optical device material and are expected as one of the material supporting the photonics age in the 21th century. F
F
F
F
F
F
S
F
CH3
F
F
F
CH3 CH3
S
S
CH3 CH3
F
F
CH3 S
2
1
B2629
B2287 F
CH3
Diarylethenes
S
F
F
F
F
F
CH3 CH3
F CH3
B1535 O
O
O
CH3
S
CH3 CH3
S
CH3
CH3
CH3
CH3
F
CH3 CH3
S
B1536
O
CH3
F
F
S
S
B1534
F
F
H N
NC
O CH3
S
CH3 CH3
S
CH3
CN CH3
CH3 CH3
S
CH3 CH3
S
CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
247
Photochromic Compounds
Product No. Product Name B2629 B2287 B1534 B1535 B1536
Unit Size
1,2-Bis(2,4-dimethyl-5-phenyl-3-thienyl)-3,3,4,4,5,5-hexafluoro-1-cyclopentene 1,2-Bis[2-methylbenzo[b]thiophen-3-yl]-3,3,4,4,5,5-hexafluoro-1-cyclopentene 2,3-Bis(2,4,5-trimethyl-3-thienyl)maleic Anhydride 2,3-Bis(2,4,5-trimethyl-3-thienyl)maleimide cis-1,2-Dicyano-1,2-bis(2,4,5-trimethyl-3-thienyl)ethene
H1042
T0344
T0416
N HOH2CH2C
T0423 CH3
CH3
CH3
CH3
CH3
N
O
Br
O
CH3
CH3
T1259
CH3
CH3
N
NO2
O
1g 1g 1g 1g 5g
T0370 CH3
CH3 CH3
Spiropyrans
100mg 100mg 100mg 100mg 1g
T0366
CH3 CH3
CH3 CH3
N
N
O CH3 CH3O
N
O
N
CH3
O
N
CH3
O
NO2
CH3
Product No. Product Name H1042 T0344 T0370 T0416 T0423 T1259 T0366
Unit Size
1-(2-Hydroxyethyl)-3,3-dimethylindolino-6'-nitrobenzopyrylospiran 1,3,3-Trimethylindolinobenzopyrylospiran 1,3,3-Trimethylindolino-6'-bromobenzopyrylospiran 1,3,3-Trimethylindolino-8'-methoxybenzopyrylospiran 1,3,3-Trimethylindolino-β-naphthopyrylospiran 1,3,3-Trimethylindolinonaphthospirooxazine 1,3,3-Trimethylindolino-6'-nitrobenzopyrylospiran
D3618
1g 1g
5g 5g 1g 25g 5g 1g 25g
1g 1g 1g
D3619 NH2
O NH2
Spiroperimidines
HN
NH
NH NH
HN
Product No. Product Name D3618 D3619
Unit Size
2,3-Dihydro-2-spiro-4'-[8'-aminonaphthalen-1'(4'H)-one]perimidine (contains o-form) 2,3-Dihydro-2-spiro-7'-[8'-imino-7',8'-dihydronaphthalen-1'-amine]perimidine
B0469
100mg 100mg
B1518 NO2
Viologens (Related Compounds)
248
N
N
O2N
O2N
N
N
NO2
2Cl
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Photochromic Compounds
D2137
D1593
CH2 N
N CH2
2Cl
CH3(CH2)6 N
. xH2O
D1854
D0713 D3685 N (CH2)6CH3
CH3 N
N CH3
2Cl
CH3(CH2)7 N
N
. xH2O
2Br
(CH2)7CH3
2Br
D2165
N
N 2Cl
Product No. Product Name B0469 B1518 D2137 D1593 D0713 D3685 D1854 D2165
Unit Size
4,4'-Bipyridyl 1,1'-Bis(2,4-dinitrophenyl)-4,4'-bipyridinium Dichloride 1,1'-Dibenzyl-4,4'-bipyridinium Dichloride Hydrate 1,1'-Diheptyl-4,4'-bipyridinium Dibromide 1,1'-Dimethyl-4,4'-bipyridinium Dichloride Hydrate 1,1'-Dimethyl-4,4'-bipyridinium Dichloride 1,1'-Di-n-octyl-4,4'-bipyridinium Dibromide 1,1'-Diphenyl-4,4'-bipyridinium Dichloride
1g
25g 5g 5g 1g 1g
500g 25g 25g 5g 10g 5g 5g 1g
Others Product No. Product Name A0565 D3197 N0346 T1489
Unit Size
Azobenzene 3,3-Diphenyl-3H-naphtho[2,1-b]pyran 2,5-Norbornadiene (stabilized with BHT) Thioindigo
25g 25ml
500g 5g 500ml 25g
References 1) 2) 3) 4) 5) 6)
E. Fischer, Y. Hirshberg, . 1952, 4522. G. H. Brown, in S. Irie, T. Yamaguchi, H. Nakazumi, S. Kobatake, M. Irie, 2001, S. Kohata, M. Irie, , 19. M. Irie, . 2000, , 1685. 2003, number K. Matsuda, M. Irie, , 2.
, Wiley-Interscience, 1971. . 1999, , 1139.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
249
Liquid Crystals & Related Compounds
Liquid Crystals & Related Compounds Liquid crystals possess properties of both the liquid and solid phases, which results in the characteristic fluidity and optical birefringence (anisotropy) properties. Generally, the liquid crystal molecules consist of long chain moiety, rigid core and readily polarized functional groups. In some instances, they may form into plate shapes. In the liquid crystal state, the molecules are constrained to rotate, and line up into a regular array. Depending on how these molecules are arranged, the liquid crystal phases are classified as nematic, smectic or cholesteric phases. The regularity of these molecular arrangement is reflected in the anisotropic properties of permittivity and refractive index. Therefore, it is possible to control the optical property of the liquid crystal by changing the molecular arrangement electrically. The response speed of liquid crystals is fast due to the fluidity properties, and phase changes can easily occur both electrically and by heating.1) The application of liquid crystals for display purposes originated in HeiMeir when he and his co-workers (1968) reported using light scattering in the display material.2) Since then, Schiff base3) and azoxybenzene types4) were also developed; both have shown liquid crystalline state at room temperature. These developments have fundamentally contributed to today's prosperity within the liquid crystal industry. Some related compounds are shown as follows.
C0319
C0320 CH3 H3C
C0694 H3C H3C
CH3
CH3
H3C
C0617
C0618 H3C H3C
CH3 H3C
H3C
H3C H3C
CH3
HCOO
C0692 H3C H3C
CH3 H3C
CH3 CH3
H3C
COOH
C0321
H3C H3C
CH3(CH2)10COO
C0559
CH3
H3C CH3 H3C
CH3
H3C
H3C
CH3 CH3
H3C
C0334
CH3
H3C H3C
CH3 CH3
HOCO(CH2)2COO
H3C H3C
CH3
H3C
C0620
H3 C
C0675 CH3
C0674
H3C
CH3
H3C
CH3(CH2)4COO
CH3
CH3
H3C H3C
CH3(CH2)5COO
CH3
COO
Ph(CH2)2COO
CH3 CH3
H3C
H3C
COO
C0619
C0673
CH3
H3C
CH3
CH3(CH2)8COO
C0672
CH3
H3C
H3C H3C
PhCH=CHCOO
CH3
CH3
H3C
CH3 CH3
H3C
C0671
Cl
BzO
CH3
ClCOO
C1260
Cl
CH3COO
H3C
CH3 CH3
H3C
CH3
H3C
CH3
CH3(CH2)2COO
CH3
H3C
Cholesteryl Compounds
C0668
CH3 H3C
CH3
H3C
CH3 CH3
CH3 CH3
H3C
H3C
O O
250
O (CH2)7
(CH2)4CH3
O
O
CH3(CH2)6COO
(CH2)12CH3
O
(CH2)7
(CH2)7CH3
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Liquid Crystals & Related Compounds
C0322
N0347 CH3 H3C
C0693
CH3
CH3 H3C
CH3
H 3C
C0676
H3C
CH3(CH2)7COO
C0323 CH3 H3C
CH3
CH3 H3C
H3C
C0610 CH3 H3C
CH3
CH3 H
CH3
H3C
H3C
CH3(CH2)16COO
CH3CH2COO
C0695
CH3
H3C H
Unit Size 25g 25g
25g 10g 5g 25g 25g 10g 25g
C0720
CH3
CH3 H3C
CH3
H3C O
CH3(CH2)3O C O
C0725
C0719 CH3
CH3
H3C
CH3
CH3
CH3 H3C
CH3
H3C O CH3(CH2)5O C O
CH3 CH3
O
CH3(CH2)4O C O
H3C O CH3(CH2)6O C O
CH3 H3C H 3C
O
B0264 CH3 H3C
CH3 CH3
H 3C
Cholesteryl Alkyl Carbonates
500g 25g 500g 25g 25g 25g 25g 10g 25g 25g 10g 10g 10g 25g 500g 25g 25g 500g 25g 500g 10g 25g 500g 10g 10g 25g
C0718 CH3 H3C
CH3CH2O C O
H
Cholesterol Acetate Cholesterol Benzoate Cholesterol Butyrate Cholesterol Chloroformate Cholesterol trans-Cinnamate Cholesterol Decanoate Cholesterol 2,4-Dichlorobenzoate Cholesterol Formate Cholesterol Heptanoate Cholesterol Hexanoate Cholesterol Hydrocinnamate Cholesterol Hydrogen Phthalate Cholesterol Hydrogen Succinate Cholesterol Laurate Cholesterol Linoleate Cholesterol Myristate Cholesterol n-Octanoate Cholesterol Oleate Cholesterol Palmitate Cholesterol Pelargonate Cholesterol Phenylacetate Cholesterol Propionate Cholesterol Stearate Cholesterol Valerate Cholesteryl Bromide from Beef Fat Cholesteryl Chloride from Beef Fat
C0716
CH3
Cl
Product No. Product Name C0319 C0320 C0668 C0694 C0617 C0618 C1260 C0671 C0672 C0673 C0619 C0692 C0674 C0620 C0321 C0675 C0334 C0559 C0322 N0347 C0693 C0676 C0323 C0677 C0695 C0610
H
H H
Br
CH3
CH3 H3C
CH3
H H
CH3(CH2)3COO
CH3
H3C
PhCH2COO
C0677
CH3
H3C
CH3
H3C
H3C
CH3(CH2)14COO
CH3
CH3
CH3
CH3 CH3
CH3 CH3
H3C O (CH3)2CHCH2O C O
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
251
Liquid Crystals & Related Compounds
C0717
C0715 CH3 H3C
B0256 CH3
CH3
C0721
CH3
H3C H3 C
H3C O
CH3 H3C
CH3
CH3O C O
CH3 CH3
H 3C
H3C O
O CH3(CH2)8O C O
O
(CH3)2CHO C O
CH3
CH3 H3C
CH3
CH3
CH3(CH2)7O C O
C0691 CH3
CH3
H3C
CH3
H3C
O O
O(CH2)8
(CH2)7CH3
Product No. Product Name C0720 C0718 C0716 B0264 C0725 C0719 C0717 C0715 B0256 C0721 C0691
Unit Size
Cholesterol Amyl Carbonate Cholesterol Butyl Carbonate Cholesterol Ethyl Carbonate Cholesterol Heptyl Carbonate Cholesterol Hexyl Carbonate Cholesterol Isobutyl Carbonate Cholesterol Isopropyl Carbonate Cholesterol Methyl Carbonate Cholesterol Nonyl Carbonate Cholesterol n-Octyl Carbonate Cholesterol Oleyl Carbonate
1g
1g 10g
C0772
10g 10g 10g 10g 10g 10g 10g 10g 10g 10g 25g
A0608 O O C O(CH2)4CH3
O HOOC
Carbonates
O C O(CH2)4CH3 C O
OCH2CH3
O
C0773
E0257
O HOOC
O C O(CH2)3CH3 CH3CH2O
M0261 O O C O O C
O O C OCH3
O O C OCH2CH3
OCH2CH3
Product No. Product Name C0772 A0608 C0773 E0257 M0261
Unit Size
Amyl 4-Carboxyphenyl Carbonate Amyl 4-(4-Ethoxyphenoxycarbonyl)phenyl Carbonate Butyl 4-Carboxyphenyl Carbonate 4-(4-Ethoxyphenoxycarbonyl)phenyl Ethyl Carbonate Methyl 4-(4'-Ethoxyphenoxycarbonyl)phenyl Carbonate
1g
B0063
B0077
Phenyl Esters
252
P0896 OH
O C O
1g 1g 5g 1g 1g
O Cl
C O
O CH3(CH2)4
C O
O(CH2)3CH3
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Liquid Crystals & Related Compounds
S0274
S0129
B1586 OH
OH
H0810
HOOC O
O t
C O
Bu
P0305
I0416
O
O C O
CH2 CHCH2CH2O
C O
CN
CH3(CH2)6
C O
CN
PhOOC
B0375
B1091
P0897
COOPh
H0766
COOPh O CH3(CH2)3
C O
OCH2CH3
O C O
CH3(CH2)3
O
O
O(CH2)5CH3
CH3(CH2)4
C O
O(CH2)5CH3
HO(CH2)6O
C O
OCH3
COOPh
M2106
B1108
A0842
S0146
B1092
O C O
OCH3
O
NH2 O
C O
OH O
C O
NO2
C O
NO2
O C O
CH3(CH2)3
O(CH2)7CH3
OCH2CH2CH CH2
P0898
S0016
B0075
O
OH O CH3(CH2)4
C O
S0017
O O(CH2)7CH3
C O
HO
OH
O C O
C O
T1370
OH
O
O
C O
C O
O CH3
CH3OOC
O C
Product No. Product Name B0063 B0077 P0896 S0274 S0129 B1586 H0810 I0416 P0305 B0375 B1091 P0897 H0766 M2106 B1108 A0842 S0146 B1092 P0898 S0016 B0075 H0218 H0797 S0017
H0797
O
C O
(CH2)7CH3
S0018 OH
H0218
Benzoic Acid 4-Chlorophenyl Ester Benzoic Acid 3-Hydroxyphenyl Ester 4-Butoxyphenyl 4-Pentylbenzoate 4-tert-Butylphenyl Salicylate 2-Carboxyphenyl Salicylate 4-Cyanophenyl 4-(3-Butenyloxy)benzoate 4-Cyanophenyl 4-Heptylbenzoate Diphenyl Isophthalate Diphenyl Phthalate 4-Ethoxyphenyl 4-Butylbenzoate 4-(Hexyloxy)phenyl 4-Butylbenzoate 4-Hexyloxyphenyl 4-Pentylbenzoate 4-(6-Hydroxyhexyloxy)benzoic Acid 4-Methoxyphenyl Ester 4-Methoxyphenyl 4-(3-Butenyloxy)benzoate 2-Naphthyl Benzoate 4-Nitrophenyl Anthranilate 4-Nitrophenyl Salicylate 4-n-Octyloxyphenyl 4-Butylbenzoate 4-n-Octyloxyphenyl 4-Pentylbenzoate 4-Octylphenyl Salicylate Phenyl Benzoate Phenyl 4-Hydroxybenzoate Phenyl 1-Hydroxy-2-naphthoate Phenyl Salicylate
O C O
COOCH3
Unit Size
25g 25g 1g 10g 25g
25g 5g
25g 25g 25g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 25g 1g 500g 500g 1g 5g 25g 500g 1g 1g 1g 100mg 1g 500g 25g 25g 1g 5g 25g 500g 500g 500g 500g
253
Liquid Crystals & Related Compounds
Product No. Product Name S0018 T1370
Unit Size
Salicylic Acid p-Tolyl Ester Terephthalic Acid Bis[4-(methoxycarbonyl)phenyl] Ester
25g 25g
B0253
B0261
N CH CH3(CH2)4O
Schiff Bases
B0372
B0252
CH N
B1713
B0374
CH N CH3(CH2)3O
O C CH3
CH N
CN
(CH2)4CH3 O
CH3(CH2)3O
CH
N
CN
CH3(CH2)3O C O
CH
N
OCH3
O(CH2)3CH3
B0255
C0743
C0744
C0742
O CH3O
CH N
CH
CH
C O(CH2)3CH3
E0254
CH3(CH2)3O
CN
E0262 O
CH
N CH
N
CH3CH2O
N CH
CN
E0240
CH3(CH2)5O
N CH
CN
M0602
(CH2)3CH3
C CH3 CH3CH2O
CH
N
CN
CH3O
CH N
CH CHCOOCH2CH3
OCH2CH3
N CH OCH2CH3
H0419
M0581
M0583
M0604
O CH CH3(CH2)5O
CH N
N
N N
O C CH3
CH3O
CN
N CH
OCH3
M0588
M0603
CH N
CH CHCOOH
CH3O
M0582
CH
N
CH CH
N
CN
OCH3
M0275 CH
CH3O
CH
CH3O
CH
N
(CH2)3CH3
N
OCH3
M0605
B0250
B0875
B0871 CH
N
F
OH CH3O
CH
N
OH
CH3O
CH N
CH3CH2O
(CH2)3CH3 CH
254
N
N CH
CH N
OCH2CH3
F
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Liquid Crystals & Related Compounds
Product No. Product Name B0253 B0261 B0372 B0252 B1713 B0374 B0255 C0743 C0744 C0742 E0254 E0262 E0240 M0602 H0419 M0581 M0583 M0604 M0588 M0603 M0582 M0275 M0605 B0250 B0875 B0871
Unit Size
4'-(Amyloxy)benzylidene-4-cyanoaniline Benzylidene-2-naphthylamine N-(4-Butoxybenzylidene)-4-acetylaniline 4'-Butoxybenzylidene-4-cyanoaniline 4-Butoxybenzylidene-4'-pentylaniline 4'-Butoxycarbonyloxybenzylidene-4-methoxyaniline Butyl 4-[(4-Methoxybenzylidene)amino]cinnamate 4'-Cyanobenzylidene-4-butoxyaniline 4'-Cyanobenzylidene-4-ethoxyaniline 4'-Cyanobenzylidene-4-hexyloxyaniline N-(4-Ethoxybenzylidene)-4-acetylaniline 4'-Ethoxybenzylidene-4-butylaniline 4'-Ethoxybenzylidene-4-cyanoaniline Ethyl 4-[(4-Methoxybenzylidene)amino]cinnamate 4'-Hexyloxybenzylidene-4-cyanoaniline N-(4-Methoxybenzylidene)-4-acetoxyaniline 4-[(4-Methoxybenzylidene)amino]azobenzene 4-[(4-Methoxybenzylidene)amino]benzonitrile 4-[(4-Methoxybenzylidene)amino]cinnamic Acid 4-[(Methoxybenzylidene)amino]stilbene N-(4-Methoxybenzylidene)aniline N-(4-Methoxybenzylidene)-4-butylaniline 4-(4-Methoxybenzylidene)-4-hydroxyaniline N-(4-Methoxy-2-hydroxybenzylidene)-4-butylaniline Terephthalbis(4-fluoroaniline) Terephthalbis(p-phenetidine)
25g
5g
5g
1g 25g 1g 1g 5g 1g 1g 1g 1g 1g 1g 500g 1g 1g 1g 25g 10g 1g 1g 1g 25g 25g 5g 1g 10g 25g
B0878
Cl
Benzidines
CH3O
Cl
CH N
N CH
OCH3
Product No. Product Name
Unit Size
3,3'-Dichloro-N,N '-bis(4-methoxybenzylidene)benzidine
B0878
25g
A0554
CH3O
A0683
N N
Azoxybenzenes
D1093
CH3(CH2)4O
D1096
N
N O
O(CH2)4CH3
OCH3 CH3CH2O
CH3(CH2)3O
D0553
N
N O
O(CH2)3CH3
CH3(CH2)11O
N N
OCH2CH3
O
O
A1065
N
N O
O O(CH2)11CH3 CH CH O C 3 2
N N
O C OCH2CH3
O
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
255
Liquid Crystals & Related Compounds
D1092
CH3(CH2)5O
D1518
N
N
O(CH2)5CH3
CH3(CH2)8O
O
D1123
N
N
O(CH2)8CH3
CH3(CH2)7O
O
D1094
N
N
O(CH2)7CH3
CH3CH2CH2O
N N
Product No. Product Name A0554 A0683 D1093 D1096 D0553 A1065 D1092 D1518 D1123 D1094
Unit Size
4,4'-Azoxydianisole 4,4'-Azoxydiphenetole 4,4'-Diamyloxyazoxybenzene 4,4'-Dibutoxyazoxybenzene 4,4'-Didodecyloxyazoxybenzene Diethyl Azoxybenzene-4,4'-dicarboxylate 4,4'-Dihexyloxyazoxybenzene 4,4'-Dinonyloxyazoxybenzene 4,4'-Di-n-octyloxyazoxybenzene 4,4'-Dipropoxyazoxybenzene
5g 1g 1g
25g 5g 5g 1g 5g 1g 1g 100mg 1g 5g 5g
A1828
Cyanobiphenyls & Analogs
C1606
C1550
CN CH3(CH2)4
CH3(CH2)6O
H0812
CH3(CH2)4
CN CH3(CH2)6
CN
C1551
CN CH3(CH2)4O
CN
Product No. Product Name A1828 H0812 C1606 C1550 C1551
OCH2CH2CH3
O
O
Unit Size
4-(trans-4-Amylcyclohexyl)benzonitrile 4-Cyano-4'-heptylbiphenyl 4-Cyano-4'-heptyloxybiphenyl 4-Cyano-4'-pentylbiphenyl 4-Cyano-4'-pentyloxybiphenyl
5g 1g 1g
5g 1g
25g 5g 1g 25g 5g
Nematic Crystals Product No. Product Name T0697 T0698 T0699
Unit Size
Liquid Crystal, TK-LQ 2040 Electric effect type, Mesomorphic range:20-40℃ Liquid Crystal, TK-LQ 3680 Electric effect type, Mesomorphic range:36-80℃ Liquid Crystal, TK-LQ 3858 Electric effect type, Mesomorphic range:38-58℃
1g 1g 1g
References 1) 2) 3) 4)
256
H. Hattori, Y. Kakuno, G. H. HeilMeier, L. A. Zanoni, L. A. Barton, . 1968, H. Kelker, B. Scheurle, . 1969, , 884. R. Steinstrasser, L. Pohl . 1971, , 1921.
1984,
, 13.
, 1162.
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Building Blocks for Liquid Crystals
Building Blocks for Liquid Crystals The first nematic liquid crystal materials, the Schiff base types, were sensitive to moisture, while the azoxybenzene types were sensitive to light. Therefore, research to improve the stability of liquid crystals to moisture and lights had been undertaken. The chemically stable biphenylcarboxylates and cyanobiphenyls were developed one after another. The cyanobiphenyls were found to be exceptional in possessing the necessary properties of display material. They exhibited low viscosity and low voltage operation, leading to many reports on the cyanobiphenyls. The phenylcyclohexane-based liquid crystals also have low viscosity and high response speeds, thus drawing to attention their use as display material. Furthermore, these bicylic liquid crystals were modified by the addition of benzene and cyclohexane rings to produce tricyclic and tetracyclic liquid crystals. As a result, the upper range of temperature was increased. In recent years, further improvements in the various physical properties were made by introduction of fluorine and another functional groups to the liquid crystals, and there are now widely used. The optically active compounds are important components of chiral nematic liquid crystals and chiral smectic liquid crystals. More recently, antiferroelectric liquid crystals of the chiral smectic liquid crystal type, are now undergoing vigorous synthetic studies to develop novel liquid crystal compounds. Larger high-resolution displays are the target for the next generation of liquid crystal materials.
A1410
A1322
B1866
O
Br
Biphenyls
B1304
CH3(CH2)6
H0690
Br
C1239
HO
Cl
OH
CH3(CH2)6
CN
CH3(CH2)4O
CN
CH3(CH2)5O
Br
CH3(CH2)6O
CN
CH3(CH2)9O
CN
Br
HO
COOH
CH3(CH2)4O
CN
HO
COOH
CH3
CN
D1082
O(CH2)4CH3
F0704
CH2CH3
t Bu
C1741
D1090
E0463
O(CH2)5CH3
CH3(CH2)2
C O
B1986
H0523
D2041
D1089
OCH2CH3
CH3(CH2)4
COCH3
B1306
C1606
C1551
D1127
CH3CH2O
B1305
H0812
C1550
CH3(CH2)4
Br
COCH3 CH3
CH3(CH2)3O
O(CH2)3CH3
H0708
F
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
CO(CH2)5CH3
257
Building Blocks for Liquid Crystals
H0709
CH3(CH2)6
H0710
HO
CO(CH2)4CH3
COOH
H0695
H0711
B1924
COOH
CH3(CH2)5
H0767
COOH
O0214
O(CH2)17CH3
HOCH2(CH2)5O
H0819
OCH3
P1133
CO(CH2)6CH3
CH3O
OH
P1212
COCH2CH3
(CH2)4CH3
P1037
CH3CH2CH2
COOH
Product No. Product Name A1410 A1322 B1866 B1304 H0690 B1305 B1306 B1986 C1239 H0812 C1606 H0523 C1741 C1550 C1551 D2041 D1090 D1082 D1127 D1089 E0463 F0704 H0708 H0709 H0710 H0711 H0767 H0819 H0695 B1924 O0214 P1133 P1212 P1037
258
4-Acetyl-4'-bromobiphenyl 4-Acetyl-4'-methylbiphenyl 4-Biphenyl Benzoate 4-Bromo-4'-heptylbiphenyl 4-Bromo-4'-hydroxybiphenyl 4-Bromo-4'-pentylbiphenyl 4-Bromo-4'-propylbiphenyl 4-(4-tert-Butylphenyl)benzoic Acid 4-Chloro-4'-hydroxybiphenyl 4-Cyano-4'-heptylbiphenyl 4-Cyano-4'-heptyloxybiphenyl 4-Cyano-4'-hydroxybiphenyl 4-Cyano-4'-methylbiphenyl 4-Cyano-4'-pentylbiphenyl 4-Cyano-4'-pentyloxybiphenyl 4'-Decyloxybiphenyl-4-carboxylic Acid 4,4'-Diamyloxybiphenyl 4,4'-Dibutoxybiphenyl 4,4'-Diethoxybiphenyl 4,4'-Dihexyloxybiphenyl 4-Ethylbiphenyl 4-Fluoro-4'-hydroxybiphenyl 4-Heptanoylbiphenyl 4-(4-Heptylphenyl)benzoic Acid 4-Hexanoylbiphenyl 4-(4-Hexylphenyl)benzoic Acid 4-(6-Hydroxyhexyloxy)-4'-methoxybiphenyl 4-Hydroxy-4'-methoxybiphenyl 4-(4-Hydroxyphenyl)benzoic Acid 4-Octadecyloxybiphenyl 4-n-Octanoylbiphenyl 4-Pentylbiphenyl 4-Propionylbiphenyl 4-(4-Propylphenyl)benzoic Acid
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 5g 5g 5g 1g 1g 1g
1g
5g 5g 5g 1g 1g
5g
1g 5g
5ml 5g
25g 5g 25g 5g 25g 5g 25g 5g 5g 5g 1g 25g 25g 25g 5g 5g 5g 25g 5g 5g 25g 25g 25g 5g 10g 5g 1g 5g 25g 25g 10g 25ml 25g 10g
Building Blocks for Liquid Crystals
A0885
A1024
A0269
COOH
COOH
COOH
OCOCH3
COCH3
NH2
Benzoic Acids
A0741
A0708
A0482
COOH
(CH2)4CH3
B1950
B0553
COOH
COOH
COOH
O(CH2)4CH3
OCH3
OBn
Br
B1585
B0896
COOH
COOH
B1665
COOH
B0241 COOH
D2859 COOH
COOH
F
OCH2CH2CH
Br
E0045
CH2
E0379
O(CH2)3CH3
F0337
(CH2)3CH3
H0774
COOH
COOH
COOH
OCH2CH3
CH2CH3
O(CH2)7CH3
O(CH2)11CH3
H0792 COOH
COCl
F
H0248
H0829
H0247
COOH
COOH
O(CH2)6CH3
(CH2)5CH3
H0695
O0137
HO
H0207
(CH2)6CH3
H0642
COOH
COOH
O(CH2)5CH3
OH
O0117 COOH
(CH2)6CH3
P0206
COOH
O
OH
P0945
COOH
COOH
COOH
O(CH2)7CH3
OCH2CH2CH3
CH2CH2CH3
COOH
(CH2)7CH3
T0293
U0072 COOH
COOH
CH3
O(CH2)10CH3
Product No. Product Name A0885 A1024 A0269 A0741 A0708 A0482
4-Acetoxybenzoic Acid 4-Acetylbenzoic Acid 4-Aminobenzoic Acid 4-Amylbenzoic Acid 4-Amyloxybenzoic Acid p-Anisic Acid
Unit Size
5g
25g 1g 25g 25g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500g 5g 500g 250g 25g 500g
259
Building Blocks for Liquid Crystals
Product No. Product Name B1665 B0553 B1950 B1585 B0896 B0241 D2859 E0045 E0379 F0337 H0774 H0792 H0248 H0829 H0247 H0207 H0642 H0695 O0137 O0117 P0206 P0945 T0293 U0072
Unit Size
4-Benzyloxybenzoic Acid 4-Bromobenzoic Acid 4-Bromo-2-fluorobenzoic Acid 4-(3-Butenyloxy)benzoic Acid 4-Butoxybenzoic Acid 4-Butylbenzoic Acid 4-(Dodecyloxy)benzoic Acid 4-Ethoxybenzoic Acid 4-Ethylbenzoic Acid 3-Fluoro-4-n-octyloxybenzoic Acid 4-Heptylbenzoic Acid 4-Heptylbenzoyl Chloride 4-(Heptyloxy)benzoic Acid 4-Hexylbenzoic Acid 4-(Hexyloxy)benzoic Acid 4-Hydroxybenzoic Acid 4-(4-Hydroxyphenoxy)benzoic Acid 4-(4-Hydroxyphenyl)benzoic Acid 4-n-Octylbenzoic Acid 4-n-Octyloxybenzoic Acid 4-Propoxybenzoic Acid 4-Propylbenzoic Acid p-Toluic Acid 4-Undecyloxybenzoic Acid
5g 25g 5g
5g 5g
1g 5g 25g
1g
25g 25g 1g 5g 5g
25g 25g
A1467
A0707
25g 500g 25g 5g 25g 25g 25g 25g 25g 5g 10g 25g 500g 5g 500g 500g 5g 25g 25g 25g 25g 500g 500g 5g
A0480
CHO
CHO
CHO
OCOCH3
O(CH2)4CH3
OCH3
Benzaldehydes
B1325
B0549
B2002
CHO
B0126 CHO
CHO
B1014 CHO
CHO
F
OBn
Br
D1124
E0042
E0325
H0238
(CH2)3CH3
H0166
CHO
CHO
CHO
CHO
CHO
O(CH2)9CH3
OCH2CH3
CH2CH3
O(CH2)6CH3
O(CH2)5CH3
H0198
260
O(CH2)3CH3
Br
O0223
O0116
P0182
T0259
CHO
CHO
CHO
CHO
CHO
OH
O(CH2)17CH3
O(CH2)7CH3
OCH2CH2CH3
CH3
Product No. Product Name
Unit Size
A1467 A0707 A0480 B1325 B0549 B2002
5g 25ml 25ml 25g 25g 5g
4-Acetoxybenzaldehyde 4-Amyloxybenzaldehyde p-Anisaldehyde 4-Benzyloxybenzaldehyde 4-Bromobenzaldehyde 4-Bromo-2-fluorobenzaldehyde
Availability, price or specification of the listed products are subject to change without prior notice.
25g 500ml 500ml 500g 250g 25g
Building Blocks for Liquid Crystals
Product No. Product Name B0126 B1014 D1124 E0042 E0325 H0238 H0166 H0198 O0223 O0116 P0182 T0259
Unit Size
4-Butoxybenzaldehyde 4-Butylbenzaldehyde 4-Decyloxybenzaldehyde 4-Ethoxybenzaldehyde 4-Ethylbenzaldehyde 4-Heptyloxybenzaldehyde 4-(Hexyloxy)benzaldehyde 4-Hydroxybenzaldehyde 4-Octadecyloxybenzaldehyde 4-n-Octyloxybenzaldehyde 4-Propoxybenzaldehyde p-Tolualdehyde
5ml 5g 25g 25ml
25g
25ml
A0384
A0728
25ml 25ml 25g 500g 500ml 25ml 25g 500g 5g 25g 25ml 500ml
P0843
OH
OH
OH
NH2
O(CH2)4CH3
(CH2)4CH3
Phenols
H0239
B0945
B1835
OH
H0690
B0787
OH HO
C
OH F
CF3 OH
Br
OH
CF3
CH2Ph
B0923
Br
Br
B1026
C0400
D2304
OH
OH
OH
E0216 OH
OH CH3
O(CH2)3CH3
E0159
(CH2)3CH3
F0160 OH
CH2CH3
H0611
H0441
H0615
H0439
OH
OH
OH
OH
F
O(CH2)6CH3
(CH2)6CH3
O(CH2)5CH3
H0198 OH
OCH2CH3
(CH2)11CH3
CH3
H0207 OH
H0642 OH
H0695
COOH
HO
(CH2)5CH3
M0123
CHO
COOH
H0825 OH
OCH3
O0140
O C O
OH
OCH3
O
COOH
OH
P0955
P0698
OH
OH
OH
O(CH2)7CH3
OCH2CH2CH3
CH2CH2CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
261
Building Blocks for Liquid Crystals
Product No. Product Name A0384 A0728 P0843 H0239 B0945 B1835 H0690 B0787 B0923 B1026 C0400 D2304 E0216 E0159 F0160 H0441 H0615 H0439 H0611 H0198 H0207 H0642 H0695 M0123 H0825 O0140 P0955 P0698
Unit Size
4-Aminophenol 4-(Amyloxy)phenol 4-Amylphenol 4-Benzylphenol 2,2-Bis(4-hydroxyphenyl)hexafluoropropane 4-Bromo-2-fluorophenol 4-Bromo-4'-hydroxybiphenyl 4-Bromophenol 4-Butoxyphenol 4-Butylphenol p-Cresol 4-Dodecyl-o-cresol 4-Ethoxyphenol 4-Ethylphenol 4-Fluorophenol 4-Heptyloxyphenol 4-Heptylphenol 4-Hexyloxyphenol 4-Hexylphenol 4-Hydroxybenzaldehyde 4-Hydroxybenzoic Acid 4-(4-Hydroxyphenoxy)benzoic Acid 4-(4-Hydroxyphenyl)benzoic Acid 4-Methoxyphenol 4-Methoxyphenyl 4-Hydroxybenzoate 4-n-Octyloxyphenol 4-Propoxyphenol 4-Propylphenol
25g 25ml 25g 5g 5g 5g 25g 25g 5g 25g 25g 25g 25g 5g 5g 5g 25g 25g 1g 5g 25g 5g 5g 5g
A0269
A0384
500g 5g 500ml 500g 25g 25g 25g 500g 500g 25g 500g 10g 500g 500g 500g 5g 25g 25g 25g 500g 500g 5g 25g 500g 25g 25g 25g 25g
A0938
NH2
NH2
COOH
OH
NH2
Anilines
A0487
B1393
B1003
B0272
NH2
NH2
NH2
OCH3
Br
O(CH2)3CH3
H0588
H0890 NH2
(CH2)6CH3
O0186 NH2
(CH2)5CH3
E0061
(CH2)7CH3
(CH2)3CH3
CH2CH3
B0271 NH2
NH2
OCH2CH3
CH2CH2CH3
T0300 NH2
CH3
262
NH2
NH2
P0090 NH2
(CH2)4CH3
Availability, price or specification of the listed products are subject to change without prior notice.
Building Blocks for Liquid Crystals
Product No. Product Name A0269 A0384 A0938 A0487 B1393 B1003 B0272 E0061 H0588 H0890 O0186 P0090 B0271 T0300
Unit Size
4-Aminobenzoic Acid 4-Aminophenol 4-Amylaniline p-Anisidine 4-Bromoaniline 4-Butoxyaniline 4-Butylaniline 4-Ethylaniline 4-Heptylaniline 4-Hexylaniline 4-n-Octylaniline p-Phenetidine 4-Propylaniline p-Toluidine
25g 25g 25g 25g 5g 25ml 25ml 5ml 5g 25g 25g
B0537
B1501
500g 500g 25ml 500g 500g 25g 500ml 500ml 25ml 25g 25g 500g 25ml 500g
B1000
COCH3
COCH3
Br
O(CH2)3CH3
COCH3
Acetophenones
E0318
H0678 COCH3
H0669 COCH3
CH2CH3
(CH2)6CH3
O0207
P1035 COCH3
(CH2)5CH3
M0135 COCH3
COCH3
OCH3
CH3
P1036 COCH3
(CH2)7CH3
M0105 COCH3
(CH2)3CH3
COCH3
(CH2)4CH3
CH2CH2CH3
Product No. Product Name B0537 B1501 B1000 E0318 H0678 H0669 M0105 M0135 O0207 P1035 P1036
Unit Size
4'-Bromoacetophenone 4'-Butoxyacetophenone 4'-Butylacetophenone 4'-Ethylacetophenone 4'-Heptylacetophenone 4'-Hexylacetophenone 4'-Methoxyacetophenone 4'-Methylacetophenone 4'-n-Octylacetophenone 4'-Pentylacetophenone 4'-Propylacetophenone
25g 25g 25ml
25g 25ml 5g 25g
A0695
A1213 CN
500g 5g 500g 500ml 25ml 25g 500g 500ml 25g 25g 500g
A1249 CN CF3 NC
Benzonitriles NH2
NH2
NH2
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
263
Building Blocks for Liquid Crystals
B1365
B1426
C0135
C1141
C0443
CN
CN
CN
CN
CN
OBn
Br
Cl
COCH3
CHO
C0445
C1182 CN
C1985
C1299
H0523
CN
CN
CN COOH
F0221
H0778
C0842
P1617
CN
CN CH3CH2
CN
CH2Cl
COCl
E0703
HO
CN
CN
CH3CH2CH2
(CH2)6CH3
F
CN
OH
T0307 CN
CH3
Product No. Product Name A0695 A1213 A1249 B1365 B1426 C0135 C1141 C0443 C0445 C1182 C1985 C1299 H0523 E0703 F0221 H0778 C0842 P1617 T0307
Unit Size
4-Aminobenzonitrile 5-Amino-2-cyanobenzotrifluoride 4-Amino-4'-cyanobiphenyl 4-Benzyloxybenzonitrile 4-Bromobenzonitrile 4-Chlorobenzonitrile 4'-Cyanoacetophenone 4-Cyanobenzaldehyde 4-Cyanobenzoic Acid 4-Cyanobenzoyl Chloride 4-Cyanobenzyl Chloride 4-Cyanobiphenyl 4-Cyano-4'-hydroxybiphenyl 4-(trans-4-Ethylcyclohexyl)benzonitrile 4-Fluorobenzonitrile 4-Heptylbenzonitrile 4-Hydroxybenzonitrile 4-(trans-4-Propylcyclohexyl)benzonitrile p-Tolunitrile
10g 1g 1g
5g
25g 25g 10g 5g 25g 5g 5g 5g 25g 1ml 25g 25g
B2986
B1136
M1621
O
O
O
C OH
C OH
C OH
4-Alkylcyclohexanecarboxylic Acids (CH2)3CH3
264
(CH2)3CH3
Availability, price or specification of the listed products are subject to change without prior notice.
CH3
250g 5g 5g 25g 250g 500g 25g 25g 250g 25g 25g 25g 25g 5g 500g 5ml 500g 5g 500g
Building Blocks for Liquid Crystals
M1783
P0944
P1656
P0943
O
O
O
O
C OH
C OH
C OH
C OH
CH2CH2CH3
CH2CH2CH3
(CH2)4CH3
CH3
Product No. Product Name B2986 B1136 M1621 M1783 P0944 P1656 P0943
Unit Size
4-Butylcyclohexanecarboxylic Acid (cis- and trans- mixture) trans-4-Butylcyclohexanecarboxylic Acid 4-Methylcyclohexanecarboxylic Acid (cis- and trans- mixture) trans-4-Methylcyclohexanecarboxylic Acid trans-4-Pentylcyclohexanecarboxylic Acid 4-Propylcyclohexanecarboxylic Acid (cis- and trans- mixture) trans-4-Propylcyclohexanecarboxylic Acid
B1907
5g 5g 5g 5g 5g 5g 5g
B1611
B1612 B1802 Br
Br
25g 25g 25g 25g 25g 25g 25g
Br
4-Alkylbromobenzenes
B1879
B1608
B1606 Br
Br
B1889
B1605 Br
(CH2)4CH3
Br
(CH2)7CH3
(CH2)8CH3
B0661 Br
Br
CH2CH2CH3
CH3
Product No. Product Name B1907 B1611 B1612 B1802 B1879 B1608 B1606 B1596 B1610 B2117 B1605 B1889 B0661
B1610 B2117 Br
(CH2)5CH3
(CH2)6CH3
CH2CH3
B1596 Br
(CH2)11CH3
(CH2)9CH3
(CH2)3CH3
1-Bromo-4-butylbenzene 1-Bromo-4-decylbenzene 1-Bromo-4-dodecylbenzene 1-Bromo-4-dodecylbenzene 1-Bromo-4-ethylbenzene 1-Bromo-4-heptylbenzene (stabilized with Copper chip) 1-Bromo-4-hexylbenzene 1-Bromo-4-nonylbenzene 1-Bromo-4-n-octylbenzene 1-Bromo-4-n-octylbenzene 1-Bromo-4-pentylbenzene 1-Bromo-4-propylbenzene 4-Bromotoluene
Unit Size 1g
5g 5g 5g 5g 1g 5g 5g 5g 5g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 25g 25g 25g 25g 5g 25g 25g 25g 5g 25g 5g 500g
265
Building Blocks for Liquid Crystals
A1024
A0269
A1278
COOH
COOH
COOH
COCH3
NH2
NH2
Bifunctional Compounds
A0384
B1665
B1104
B0537
B1393
OH
COOH
OH
COCH3
NH2
NH2
OBn
OBn
Br
Br
B0549
B0553 CHO
H0690
H0198
COOH Br
Br
H0642
COOH
OH
OH
OH
Br
H0612
H0207 CHO
H0695
COOH COOH HO
COOH
HO O
OH
Product No. Product Name A1024 A0269 A1278 A0384 B1665 B1104 B0537 B1393 B0549 B0553 H0690 H0198 H0207 H0612 H0642 H0695
Unit Size
4-Acetylbenzoic Acid 4-Aminobenzoic Acid 4-Aminocyclohexanecarboxylic Acid (cis- and trans- mixture) 4-Aminophenol 4-Benzyloxybenzoic Acid 4-(Benzyloxy)phenol 4'-Bromoacetophenone 4-Bromoaniline 4-Bromobenzaldehyde 4-Bromobenzoic Acid 4-Bromo-4'-hydroxybiphenyl 4-Hydroxybenzaldehyde 4-Hydroxybenzoic Acid 6-Hydroxy-2-naphthoic Acid 4-(4-Hydroxyphenoxy)benzoic Acid 4-(4-Hydroxyphenyl)benzoic Acid
H0923
5g
H1201 OAc
266
OH Br
OH
AcO
Br
HO
AcO
Br
HO
. xH2O
Br
OAc OAc
5g 500g 25g 500g 25g 500g 500g 500g 250g 500g 25g 500g 500g 500g 5g 25g
H0907 Br
OAc
Building Blocks for Discotic Liquid Crystals
1g 25g 5g 25g 5g 25g 25g 25g 25g 25g 5g 25g 25g 25g 1g 5g
Br
Availability, price or specification of the listed products are subject to change without prior notice.
OH OH
Building Blocks for Liquid Crystals
H0898 OCH3 OCH3 CH3O CH3O OCH3 OCH3
Product No. Product Name H0923 H1201 H0907 H0898
Unit Size
2,3,6,7,10,11-Hexaacetoxytriphenylene 2,3,6,7,10,11-Hexabromotriphenylene 2,3,6,7,10,11-Hexahydroxytriphenylene Hydrate 2,3,6,7,10,11-Hexamethoxytriphenylene
100mg 100mg 1g 5g 1g 5g
Chiral Compounds Product No. Product Name B0926 B0925 C2109 C1377 C1365 C1372 C1371 C1373 L0144 M0170 M0965 M0964 H0705 H0704 H0703 H0702 L0136 M0966 M0963 O0145 O0144 P0744 P0743 P0795 P0796
(R)-(-)-2-Butanol (S)-(+)-2-Butanol (R)-2-Chlorobutyric Acid (S)-2-Chlorobutyric Acid (S)-2-Chloro-3-methylbutyric Acid (2S,3S)-2-Chloro-3-methylvaleric Acid (S)-2-Chloro-4-methylvaleric Acid (S)-(-)-2-Chloropropionic Acid Lithium L-Lactate (S)-(-)-2-Methyl-1-butanol (S)-(+)-5-Methyl-1-heptanol (S)-(+)-4-Methyl-1-hexanol Methyl (R)-(-)-3-Hydroxybutyrate Methyl (S)-(+)-3-Hydroxybutyrate Methyl (R)-(-)-3-Hydroxyisobutyrate Methyl (S)-(+)-3-Hydroxyisobutyrate Methyl D-(+)-Lactate (S)-(+)-6-Methyl-1-octanol (S)-(+)-3-Methyl-1-pentanol (R)-(-)-2-Octanol (S)-(+)-2-Octanol (R)-(-)-2-Pentanol (S)-(+)-2-Pentanol (R)-(+)-1-Phenylethyl Alcohol (S)-(-)-1-Phenylethyl Alcohol
Unit Size
1g
1ml 1ml 1g 1g 1g 1g 1g 5g
1g 1g
1ml 10ml 5ml 5g 5g 5g 1ml 1ml 5ml 5ml 1ml 1ml 5g 5g
5ml 5ml 5g 5g 5g 5g 5g 25g 25g 25ml 1ml 5ml 25ml 25ml 25g 25g 25g 5ml 5ml 25ml 25ml 5ml 5ml 25g 25g
Others Product No. Product Name B2127 B0884 B1772 B2297 B2741 D2151 E0505 E0564 F0423 H0234 H0385 H1175 H0612 H0995 M0586 M0576 T1773
1-Benzyloxy-4-bromobenzene 4-Bromofluorobenzene 1-Bromo-4-(trifluoromethoxy)benzene 4-Butylbenzoyl Chloride 4-Butyl-4'-hydroxychalcone 1,4-Diethynylbenzene 4-Ethynylaniline 1-Ethynyl-4-hexylbenzene 4-(4-Fluorophenylethynyl)phenol 2-Hydroxychalcone 2'-Hydroxychalcone trans-4-Hydroxycyclohexanecarboxylic Acid 6-Hydroxy-2-naphthoic Acid 6-Hydroxy-2-naphthonitrile 2-[(4-Methoxybenzylidene)amino]fluorene 4-Methoxycinnamic Acid 4-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)
Unit Size 5g 25g 5g 5g 1g 5g
5g
5g 25g 5g 25g
5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 500g 25g 25g 1g 5g 10g 25g 1g 25g 500g 25g 500g 5g 5g 25g 25g
267
Building Blocks for Liquid Crystals
References 1) 2) 3) 4) 5) 6)
268
1992, T. Kitamura, , 72. 1998, H. Numata, , 40. 1995, Y. Suzuki, , 8. 1997, , 9. T. Inukai, K. Miyazawa, G. W. Gray, G. R. Luckhurst, in P. G. Gennes, J. Prost, in
, Academic Press, 1979, pp.1-29, pp.263-284. , Oxford University Press, 1993.
Availability, price or specification of the listed products are subject to change without prior notice.
Organic Nonlinear Optical Materials
Organic Nonlinear Optical Materials The nonlinear optical material is a general term for the materials efficiently make appearance of nonlinear phenomenons optically as the responses to optical wavelength conversion, optical amplification as well as the refractive index changes due to its intensity. Nonlinear optical materials are largely divided into inorganic and organic materials. In 1930, the nonlinear optical effect related to optical wavelength conversion was predicted, which was said to be the first finding knowledge about the nonlinear optical phenomenon. In 1960, laser oscillation using inorganic material was reported. Since then researches of inorganic nonlinear optical materials were actively taken place, but now-a-days, probably there is no more that undiscovered. On the other hand, the 1982 ACS symposium report added momentum to the organic nonlinear optical material studies. Since then the studies have started to become active. It revealed organic compounds with the delocalized conjugated electrons which have excellent nonlinear optical property and high-speed responsiveness due to high mobility of electrons. The 21st Century is said to be an age of photonics. As one of the basic technology of photonics, improvements of the wavefront control technology using organic nonlinear optical effects are considered very important. Now R&D on the organic materials with excellent nonlinear optical properties, and vigorous applied studies have been carried out.
A0621
A1251
A0838
A0794
NO2 O2N
O2N
O2N
NO2
NH2
NH2
C0214
C0943
N
C1209 NH2
NH2
N
C1349
D2020 CH3
NHCH3 Cl
NH2
Cl
D2263
N(CH3)2
N CH2CN
Cl
N
O
NH C CH3
CH3 O2 N
N CH3
NO2
NO2
D2505
NO2
NO2
D0289
D2135
H0747
M0997
O CH3
O O2N
CH CH
N
CH3 CH3
H3C
CH3
N H
N H
OCH3 O2N
HN
M0909
M0985 NO2
CH3 O2N
CH CH
OCH3
N H
M1011
N H
N0529 NHCH3
NO2
CH3
N
NH2 CH3
N NO2
M1677
N0527
M0953 NO2
NH2
CH3
NO2
N0118 NHCH3
CH3
NO2
OCH3
NO2
O2N
M0999
OH O2N
CH3
N0117 NH2
NH2 NO2
N O
NO2
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
NO2
269
Organic Nonlinear Optical Materials
N0119
N0400
N0547
N0546
N0540
NH2 O2N N H
HOCH2
N H
NO2
O2N
NO2
CH3
NO2 N
N HOCH2
N H
N
N
HOCH2
N0281 O O2N
NH N H
O
Product No. Product Name A0621 A1251 A0838 A0794 C0943 C0214 C1209 C1349 D2020 D2263 D2505 D0289 D2135 H0747 M0997 M0999 M0909 M0985 M1011 N0529 M1677 N0527 M0953 N0118 N0117 N0119 N0400 N0547 N0546 N0540 N0281
2-Aminofluorene 4-Amino-4'-nitrobiphenyl 2-Amino-3-nitropyridine 2-Amino-5-nitropyridine 2-Chloro-3,5-dinitropyridine 2-Chloro-4-nitroaniline 2-Chloro-4-nitro-N-methylaniline N-Cyanomethyl-N-methyl-4-nitroaniline 2'-(N,N-Dimethylamino)-5'-nitroacetanilide 4-Dimethylamino-4'-nitrobiphenyl 4-Dimethylamino-4'-nitrostilbene 1,3-Dimethylurea N-(2,4-Dinitrophenyl)-L-alanine Methyl Ester 4-Hydroxy-4'-nitrobiphenyl 4-Methoxy-4'-nitrobiphenyl 4-Methoxy-4'-nitrostilbene (R)-(+)-2-(α-Methylbenzylamino)-5-nitropyridine (S)-(-)-2-(α-Methylbenzylamino)-5-nitropyridine N-Methyl-4-nitroaniline 2-Methyl-4-nitroaniline 3-Methyl-4-nitroaniline 3-Methyl-4-nitropyridine N-Oxide N-Methyl-4-nitro-o-toluidine 2-Nitroaniline 3-Nitroaniline 4-Nitroaniline 5-Nitroindole (S)-(-)-N-(5-Nitro-2-pyridyl)alaninol (S)-N-(5-Nitro-2-pyridyl)phenylalaninol (S)-(-)-N-(5-Nitro-2-pyridyl)prolinol 5-Nitrouracil
Unit Size 5g 1g 25g 1g 25g
1g 25g 1g 100mg
1g 25g 5g 5g 25g 25g 25g 5g
1g 5g
25g 5g 5g 250g 5g 500g 5g 5g 1g 5g 5g 500g 1g 5g 1g 5g 5g 5g 500g 25g 25g 25g 5g 500g 500g 500g 25g 100mg 1g 5g 25g
References 1) 2) 3) 4) 5) 6)
270
S. Miyata, ., Preprints of IUPAC 32nd International Symposium on Macromolecules, Kyoto, 1988, p.582. D. S. Chemla, ., in , Academic Press, New York, 1987. L. M. Hyden, . 1987, , 351. C. Flytzanis, ., in , Springer, Berlin, 1986. P. N. Prasad, ., in , Plenum, New York, 1988. A. J. Heeger, ., in , Material Research Society, Pittsbourgh, 1988.
Availability, price or specification of the listed products are subject to change without prior notice.
Phthalonitriles & Naphthalonitriles
Phthalonitriles & Naphthalonitriles Phthalocyanines (Pc) are the general term for compounds that contain the tetrabenzotetraazap-orphine (H2-Pc) ring, which is the porphyrin analog and metal phthalocyanines (M-Pc). M-Pc has attractive physical properties associated with their structures, and this has led to a broad spectrum of studies being done on synthetic methods and properties. Amongst the many synthetic methods, ones using 1,2-dicyanobenzene or 1,3-diiminoisoindoline, are the most common, since these methods produce the products in high purity.1) M-Pc possesses a large delocalized π electron system due to the tetraazaporphine ring, which leads to interesting and useful photochemical properties. The photochemical and photophysical properties of these systems have been studied extensively, and some of these compounds have been put to practical use. The weather-resistant blue and green pigments are one example, and in other examples, the photoelectric properties have been applied to optical memory disks, luminescent devices and solar batteries. M-Pc is also utilized as carrier-generation-layer of electrophotographic photoconductor.2) Furthermore, M-Pc has redox properties which find use as an electrochromic material3), which results in a reversible discoloration phenomenon caused by changing the applied electric potential. M-Pc is also used as a deodorant and antibacterial agent by selection of the appropriate central metals and the making of pendant-type polymers.1) In other examples, M-Pc has uses in M-Pc derivative sensor4), liquid crystal5), photochemical therapy for cancer and many others. M-Pc is the functional material of the 21st-Century, and more is anticipated upon further research and development. A1166
B1353
H2N
CH3(CH2)3O
CN
Phthalonitriles
B1334
CN
D2189
D1610
D3963
Cl
CN
CN
D2079
Cl
CN
CN
NH CN
CH3 O
C
NH
CN
CH3
F
D2237 CH3
NH
F
OH
D1983
CN CN
CN
OH CN
Bu
CN
CN
C1163
t
H0691
H0813
M1379
CN CH3(CH2)11O
O
CN
CH3(CH2)5O
CN
HO
CN
CH3
CN
CN CN
CN
CN
CN
CH3
N0566
N0524 NO2 CN
P1071
O2N
CN CN
CN
T0988
CH3(CH2)4O
P0404
P1070
CN
CN
CN
CN
CH3CH2CH2O
CN CN
T1402 F
NC
CN
F
NC
CN
F
CN CN F
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
271
Phthalonitriles & Naphthalonitriles
Product No. Product Name A1166 B1353 B1334 C1163 D2189 D1610 D3963 D2079 D1983 D2237 H0691 H0813 M1379 N0566 N0524 P1071 P0404 P1070 T0988 T1402
Unit Size
4-Aminophthalonitrile 4-Butoxyphthalonitrile 4-tert-Butylphthalonitrile 4-(4-α-Cumylphenoxy)phthalonitrile 4,5-Dichlorophthalonitrile 2,3-Dicyanohydroquinone 4,5-Difluorophthalonitrile 1,3-Diiminoisoindoline 4-(2',6'-Dimethylphenoxy)phthalonitrile 4-Dodecyloxyphthalonitrile 4-Hexyloxyphthalonitrile 4-Hydroxyphthalonitrile 4-Methylphthalonitrile 3-Nitrophthalonitrile 4-Nitrophthalonitrile 4-Pentyloxyphthalonitrile Phthalonitrile 4-Propoxyphthalonitrile 1,2,4,5-Tetracyanobenzene Tetrafluorophthalonitrile
5g 1g 5g 1g 5g
25g 5g 25g 5g 25g 25g 5g 25g 5g 5g 5g 5g 5g 25g 25g 5g 500g 5g 5g 25g
1g 5g 1g 1g 1g 1g 5g 1g 25g 1g 1g 5g
B1390
D2282
D2434 OH
Br
Naphthalonitriles
CN
Br
CN
CN
Br
CN
CN CN NO2 OH
D1977
D2027
D2009
N0578 NH
CN
CN
CN
CN
NH CN
O2N
CN NH
Product No. Product Name B1390 D2282 D2434 D1977 D2027 D2009 N0578
Unit Size
6-Bromo-2,3-dicyanonaphthalene 2,3-Dibromo-6,7-dicyanonaphthalene 2,3-Dicyano-1,4-dihydroxy-5-nitronaphthalene 2,3-Dicyanonaphthalene 2,3-Dicyano-6-nitronaphthalene 1,3-Diiminobenz[f]isoindoline 1,2-Naphthalenedicarbonitrile
1g 1g
1g
D2269
A1292
D2148 O
Others
H2N
N
CN
Cl
N
CN
H2N
NH2
CN
N N H
CN
CN
CN O
272
1g 1g 5g 10g 1g 1g 5g
Availability, price or specification of the listed products are subject to change without prior notice.
NH2
Phthalonitriles & Naphthalonitriles
D2270
D2271
D2026
D2281
H2N
N
CN
Cl
N
CN
NC
H2N
N
CN
Cl
N
CN
NC
P1218
N
D1751
CH3
N H
N
CN
N
CN
N
CN
N
CN
T1472
N
CN
O
H N
CN
CN
O
N H
CN
Product No. Product Name D2269 A1292 D2148 D2270 D2271 D2026 D2281 D1751 P1218 T1472
Unit Size
5-Amino-6-chloro-2,3-dicyanopyrazine 2-Amino-4,5-dicyano-1H-imidazole 1,4-Diamino-2,3-dicyano-9,10-anthraquinone 5,6-Diamino-2,3-dicyanopyrazine 5,6-Dichloro-2,3-dicyanopyrazine 4,5-Dicyanoimidazole 2,3-Dicyano-5-methylpyrazine 2,3-Dicyanopyrazine Pyridine-2,3-dicarbonitrile 1,4,5,6-Tetrahydro-5,6-dioxo-2,3-pyrazinedicarbonitrile
P0887
10g 25g 5g 5g 1g
T1256
P1005 P1006
tBu
N N N
Phthalocyanines
tBu
N
N
N N
Co N
10g 25g 25g 10g 25g 250g 25g 25g 5g 10g
N
N
N N
N
N
N
N Cu
N
N
N
Cu
N
N
N
N tBu
N tBu
H1194
P0774
F
F
P1018
F
F
N
N F
N N
Cu N
F
F
N
N N
N N
Fe
N F F
F
N
N
N
N
N
N
N
N
Pb
N
N
Cl
Cl
N
N N
N
Cl
N Cl
Cl Cl
N
Cl
Cl
N
N N
N Cl N Sn N Cl N
N
N
N
P0767
N N
N N
N Na2
N
N
Cu
N
Cl
Ag2
N
N
N N
P1024
Cl
N
N
N
N
N
Cl
Cl
N Cl
N
N
P0997
N
Cl
Cu
HN
N
P0973
Cl
N
N Al N Cl N
N
N Cl N Si N Cl N
N
P0660
N
N
N N
N
N
N
N
S0363
N N
P0655 P1628
N
N
N
P0996
N Li2
NH
N
N
N
N
N N
N
P0766
N
Mg
F
P1049
N
N
N
N
N
F F
N
N
N
N
F
C1167
P0355 P1795
F
F
N
N N
N
N
N N
N Sn
N
N N
N
N
N N
Zn N
N N
Cl
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
273
Phthalonitriles & Naphthalonitriles
Product No. Product Name P0887 P1005 P1006 T1256 H1194
Cobalt(II) Phthalocyanine Copper(II) Phthalocyanine (α-form) Copper(II) Phthalocyanine (β-form) Copper(II) 2,9,16,23-Tetra-tert-butylphthalocyanine 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-Hexadecafluorophthalocyanine Copper(II)
P0774 P1018 P0355 P1795 C1167 P1049 P0766 P0996 S0363 P0997 P0655 P1628 P0660 P0973 P1024 P0767
Iron(II) Phthalocyanine Magnesium(II) Phthalocyanine Phthalocyanine Phthalocyanine (purified by sublimation) Phthalocyanine Chloroaluminum Phthalocyanine Dilithium Phthalocyanine Lead Phthalocyanine Silicon Dichloride Phthalocyanine Silver Phthalocyanine Tin(IV) Dichloride Pigment Blue 15 Pigment Blue 15 (purified by sublimation) Pigment Green 7 Sodium Phthalocyanine Tin(II) Phthalocyanine Zinc Phthalocyanine
Unit Size 25g 25g 100mg
(purified by sublimation)
1g
1g
1g 1g 10g
25g 250g 500g 100mg 1g 25g 1g 25g 1g 1g 1g 25g 1g 1g 1g 25g 1g 25g 5g 5g 25g
References 1999, 1996, 1) N. Kobayashi, , 968; N. Kobayashi, , 312. 1987, 2) D. Wohrle, M. Kaneko, , 837; H. Shirai, K. Hanabusa, 1987, , 422. 3) B. Schumann, D. Wohrle, N. I. Jaeger, . 1985, , 2144; M. Chigane, 1995, , 26. 1985, 4) W. R. Barger, A. W. Snow, H. Wohltjen, L. Jarvis, , 382; A. W. Snow, W. R. Barger, M. Klusty, 1986, , 513. 2002, 5) K. Sakamoto, , 286.
274
Availability, price or specification of the listed products are subject to change without prior notice.
Macrocycles for Host-Guest Chemistry
Macrocycles for Host-Guest Chemistry Host-compounds recognize and incorporate specific molecules, atoms or ions (guests) into the molecules to form complexes. In the formation of these complexes, a variety of forces such as electrostatic interaction, hydrophobic interaction, hydrogen bonding, etc. are utilized to create high selectivity. Molecular sensors, synthetic enzymes, separation systems, etc. utilize the high guest selectivity of these host compounds. Synthesis of new host compounds with even higher selectivity are currently being developed. For example, Shinkai and co-workers have developed exciting purification techniques for fullerene C60 employing calixarene. According to these techniques, the stirring of crude fullerene and butylcalix[8]arene in toluene causes only C60 to be incorporated in the calixarene to form and precipitate a complex. Filtration and subsequent stirring of the complex in chloroform cause it to decompose to yield C60 of high purity as a precipitate. This method has been reported to be an efficient purification technique in obtaining C60 compared with conventional column purification techniques.
A1603
A1604 O
O
A1404
O
O
O
C CH3
O
O
O O
O
B1154
O
O
NH2
O
O
O
O
O
O
O
O
O
B2189 O
O O O
B2245 O
O
O
NH
O
O
B1249
O
B1539
O
O
HN
CH2
O
A1324
O
NH
C CH3
O
A1323
O
CH2OCH2CH
O
O
O
O
O
O O
A1552
O
O
O
O
Crown Ethers
A1568
B2181 O
O
O
O
O
O
O
O
O O
O
O
O O
O
C1713
C1714
O
O
O
C1942
O
O
O
Br
O
O
Br
O
C1943
C0858
O
O
O
O
O
O
O
O O
O
C OH
O O
O
C OH
O2N
O HO
O
O
N N
NO2
O
O
O
O2N
HO O
N N
O
O
O
O
O
O
NO2
O
O
C0859
C0860
C1736 O
O
O
O
O O
O
O O
D2743 O
O
O
O
O O
D2744
O
O
O
NH
O
O
O HN
HN
NH O
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
275
Macrocycles for Host-Guest Chemistry
D2323
D2877 O
D1533
O
HN
NH
O
O
O
O
O O
O
O
Bn O
N O
O
O
H0932 H N
NH
HN
NH
HN
NH
HN
NH
N H
. 6HCl
N
M1489
O
C H
O
O
O C H
O
H0983 CH2OH
O
O
O
O
N H
O
H0982 O
HN
O
O O
O
H1215 H N
H0990
O
O
O
O
O O
O O
F0451
O
O
N Bn
O
H1070
O O
O
O
O
F0448
O
O
O
O O
D1668
O
O
O
O
D2321 O
O
O
O
O
O
O
O
O
O
D2684 O
D1830
O
O
O
D2878
O
O
O
O
O
CH2OH
N
O
O O
O
N0561
N0562
O
O
P1143 O
O
O
O
O
CH2OH
O
O
O
O
O O
O
O
O
C OCH3
T1875
O
O O
O
NO2
O
O
N
NO2
O
O
O
T1874
O
O
O
T1426
T1691
T1597
O CH2 C OH
NH NH
HN
O HO C CH2
N N
N
HN
O CH2 C OH
N CH2 C OH O
T2540
T1959
O CH3CH2O C CH2
O CH2 C OCH2CH3 N
NH
HN
NH
HN
T1876
N
S
O CH2 C OCH2CH3
S
S S
T2541
NH
HN
NH HN
NH
HN
T1600
HN
NH
NH H N
H N
N O CH2 C OCH2CH3
T2642
NH HN
T1878
HN
N
. 4HCl
T1879
HN
NH
. 3HCl
N H
T1972
O O
CH2 C OC(CH3)3
CH2 C OC(CH3)3 N
O HO C CH2
N
N
O
O N
CH2 C OC(CH3)3
N CH2 C OC(CH3)3 O
HN
N
CH2 C OC(CH3)3
CH3
N
N
S
S
N
N CH2 C OC(CH3)3
CH3
CH3
S
O
Product No. Product Name A1603 A1604 A1568 A1404 A1552 A1323
276
4'-Acetylbenzo-15-crown 5-Ether 4'-Acetylbenzo-18-crown 6-Ether 2-(Allyloxymethyl)-18-crown 6-Ether 4'-Aminobenzo-15-crown 5-Ether 1-Aza-12-crown 4-Ether 1-Aza-15-crown 5-Ether
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 100mg 250mg 1g
1g 1g 1g 1g 1g 5g
Macrocycles for Host-Guest Chemistry
Product No. Product Name A1324 B1249 B1154 B1539 B2245 B2189 B2181 C1713 C1714 C1942 C1943 C0858 C0859 C0860 C1736 D2743 D2744 D2323 D2877 D1533 D2878 D1830 D2684 D2321 D1668 F0448 F0451 H1070 H1215 H0932 H0982 H0983 H0990 M1489 N0561 N0562 P1143 T1874 T1875 T1426 T1691 T1597 T2540 T1959 T1876 T1878 T1600 T2642 T2541 T1879 T1972
Unit Size
1-Aza-18-crown 6-Ether Benzo-12-crown 4-Ether Benzo-15-crown 5-Ether Benzo-18-crown 6-Ether Bis(1,4-phenylene)-34-crown 10-Ether 4'-Bromobenzo-15-crown 5-Ether 4'-Bromobenzo-18-crown 6-Ether 4'-Carboxybenzo-15-crown 5-Ether 4'-Carboxybenzo-18-crown 6-Ether 15-Crown-4 [4-(2,4-Dinitrophenylazo)phenol] 18-Crown-5 [4-(2,4-Dinitrophenylazo)phenol] 12-Crown 4-Ether 15-Crown 5-Ether 18-Crown 6-Ether 24-Crown 8-Ether 4,10-Diaza-12-crown 4-Ether 4,10-Diaza-15-crown 5-Ether 4,13-Diaza-18-crown 6-Ether Dibenzo-15-crown 5-Ether Dibenzo-18-crown 6-Ether Dibenzo-21-crown 7-Ether Dibenzo-24-crown 8-Ether Dibenzo-30-crown 10-Ether N,N '-Dibenzyl-4,13-diaza-18-crown 6-Ether Dicyclohexano-18-crown 6-Ether 4'-Formylbenzo-15-crown 5-Ether 4'-Formylbenzo-18-crown 6-Ether 1,4,7,10,13,16-Hexaazacyclooctadecane 1,4,7,10,13,16-Hexaazacyclooctadecane Hexahydrochloride 4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane 2-(Hydroxymethyl)-12-crown 4-Ether 2-(Hydroxymethyl)-15-crown 5-Ether 2-(Hydroxymethyl)-18-crown 6-Ether 4'-Methoxycarbonylbenzo-15-crown 5-Ether 4'-Nitrobenzo-15-crown 5-Ether 4'-Nitrobenzo-18-crown 6-Ether N-Phenylaza-15-crown 5-Ether 1,4,7,10-Tetraazacyclododecane 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid 1,4,7,10-Tetraazacyclododecane Tetrahydrochloride 1,4,8,12-Tetraazacyclopentadecane 1,4,8,11-Tetraazacyclotetradecane Tetraethyl 1,4,8,11-Tetraazacyclotetradecane-1,4,8,11-tetraacetate 1,4,8,11-Tetrathiacyclotetradecane 1,5,9-Triazacyclododecane 1,4,7-Triazacyclononane 1,4,7-Triazacyclononane Trihydrochloride Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetate 1,4,7-Trimethyl-1,4,7-triazacyclononane (stabilized with NaHCO3) 1,4,7-Trithiacyclononane
B1809
1g 1g 1g 1g 1g 1g 100mg
5g
100mg 1g 5g 1g 1g 1g 1g 100mg
1g 1g 1g 5g 200mg 1g 1g 1g 1g 200mg 1g 1g 200mg 200mg
Calixarenes
H0714 t
Bu
tBu
Bu
CH2 OH
1g 1g 100mg 1g
B2221 t
1ml 5ml 25g
CH2 4
5g 5g 5g 5g 100mg 5g 5g 1g 1g 100mg 100mg 5ml 25ml 100g 1g 1g 1g 5g 1g 25g 5g 5g 1g 5g 5g 1g 500mg 100mg 100mg 5g 5g 25g 1g 1g 5g 5g 5g 5g 1g 5g 1g 5g 200mg 1g 100mg 5g 5g 1g 200mg 5g 500mg
OH
CH2 5
OH
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
6
277
Macrocycles for Host-Guest Chemistry
B1750
T2563 t
C1455
H0713
C1435
tBu
Bu
CH2
OH
CH2
CH2
CH2
4
CH2
O
4
OH
6
OH
8
OH
CH2 C OCH2CH3
8
O
H0889
S0469
S0470
CH3
SO3H
S0471
U0069 SO3H
SO3H
HO
. xH2O CH2
CH2
O C CH3
OH
n
B2296
B2310
OH
6
OH
SO3Na
4
CH2 C OCH2CH3
4
S
SO2
4
O
8
4
S0477 t Bu
S
S
. H2O
CH CH3(CH2)10
. xH2O
B2312 t Bu
tBu
OH
. xH2O
n = 6,8
CH2
CH2 4
O
OH
OH
OH
4
O
Product No. Product Name B1809 B2221 H0714 B1750 T2563 C1455 H0713 C1435 H0889 S0469 S0470 S0471 U0069 B2296 B2310 B2312 S0477
Unit Size
4-tert-Butylcalix[4]arene 4-tert-Butylcalix[5]arene 4-tert-Butylcalix[6]arene (contains 5-10% Benzene) 4-tert-Butylcalix[8]arene Tetraethyl 4-tert-Butylcalix[4]arene-O,O ',O '',O '''-tetraacetate Calix[4]arene (contains ca. 8% Chloroform) Calix[6]arene (contains ca. 5% Benzene) Calix[8]arene 4-Methyl-1-acetoxycalixarene [mixture of [6] and [8]] (contains 5-10% Acetone) 4-Sulfocalix[4]arene Hydrate 4-Sulfocalix[6]arene Hydrate 4-Sulfocalix[8]arene Hydrate C-Undecylcalix[4]resorcinarene Monohydrate 4-tert-Butylthiacalix[4]arene 4-tert-Butyl-1-(ethoxycarbonylmethoxy)thiacalix[4]arene 4-tert-Butylsulfonylcalix[4]arene 4-Sulfothiacalix[4]arene Sodium Salt
C1749
Cyclophanes
1g
5g 5g 200mg 100mg 1g 1g 100mg 1g 1g 1g 1g 1g 1g 1g
D2210
N +
N +
+ N
+ N
4PF6
S
P1165
S
T1378 HN(CH2)4NH
H2C
CH2
HN(CH2)4NH
278
5g
Availability, price or specification of the listed products are subject to change without prior notice.
25g 100mg 25g 25g 1g 1g 5g 5g 1g 5g 5g 5g 1g 5g 5g 5g 5g
Macrocycles for Host-Guest Chemistry
Product No. Product Name C1749 D2210 P1165 T1378
Unit Size
Cyclobis(paraquat-1,4-phenylene) Tetrakis(hexafluorophosphate) 2,11-Dithia[3.3]paracyclophane [2.2]-Paracyclophane 1,6,20,25-Tetraaza[6.1.6.1]paracyclophane
A2122
100mg 100mg 500mg 1g 100mg
A1916
A2123
α-CD
Cyclodextrins
. xH2O
NH2
C0776
. xH2O
NH2
(2AS, 3AS)-α-CD
B3026
γ-CD
β-CD
C0869
C0900 C0777
G0263 OH O
HO HO
CH3 RO
C
. xH2O
NH2
(2AS, 3AS)-γ-CD
(2AS, 3AS)-β-CD
HO
OR
CH3
α-CD
R = permethyl-α-CD
O
γ-CD
β-CD
β-CD
H0979
M1219 OR O
HO
RO RO CH3 R=
M1356
O
7
n
M1212 O SO2Mes
O
OCH3 O
OR O
O
HO HO
HO
CH2CHO
D1732
OH O
HO HO
RO
O
O
RO
7
HO
R = H, CH3
CH3O
H
O
γ-CD
7
β-CD
n = 0,1,2...
M1876
M1956
M1741
M1957
M1644 OTs
α-CD
RO
β-CD
γ−CD α-CD
R = permethyl-α-CD
OTs
M1381
OTs
M1645
OTs
P0977
OTs
T2452
OTs
OH O
OR NH N
O 7 HO cross-linked by Epichlorohydrin
γ-CD
T1844
T1094
OR
OR
RO
HO
β-CD
T2451
RO
RO
N HN RO
NH N
OR
N HN
OR RO
OR
R = permethyl-α-CD
R = permethyl-α-CD OR
T2450 CH3
OCH3 O
OAc O AcO AcO
RO
O
CH3O 7
CH3O
C
OR
O 7
OR R = permethyl-α-CD
Product No. Product Name A2122 A1916 A2123 B3026 C0776 C0900 C0777
3A-Amino-3A-deoxy-(2AS,3AS)-α-cyclodextrin Hydrate 3A-Amino-3A-deoxy-(2AS,3AS)-β-cyclodextrin Hydrate 3A-Amino-3A-deoxy-(2AS,3AS)-γ-cyclodextrin Hydrate 2,2-Bis[4-(per-O-methyl-α-cyclodextrin-6-yloxy)phenyl]propane α-Cyclodextrin β-Cyclodextrin β-Cyclodextrin
Unit Size
10g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
1g 1g 1g 10mg 25g 500g 25g
279
Macrocycles for Host-Guest Chemistry
Product No. Product Name C0869 G0263 H0979 M1219 M1356 D1732 M1212 M1876 M1956 M1741 M1957 M1644 M1381 M1645 P0977 T2452 T2451 T1844 T1094 T2450
Unit Size
γ-Cyclodextrin 6-O-α-D-Glucosyl-β-cyclodextrin Hydroxypropyl-β-cyclodextrin 6-O-α-D-Maltosyl-β-cyclodextrin Methyl-β-cyclodextrin (mixture of several Methylated) Methyl-β-cyclodextrin (2,6-Di-O-methyl- and partially 2,3,6-Tri-O-methyl- mixture) Mono-6-O-mesitylenesulfonyl-γ-cyclodextrin Mono-6-O-(2-naphthyl)-per-O-methyl-α-cyclodextrin Mono-2-O-(p-toluenesulfonyl)-α-cyclodextrin Mono-2-O-(p-toluenesulfonyl)-β-cyclodextrin Mono-2-O-(p-toluenesulfonyl)-γ-cyclodextrin Mono-6-O-(p-toluenesulfonyl)-α-cyclodextrin Mono-6-O-(p-toluenesulfonyl)-β-cyclodextrin Mono-6-O-(p-toluenesulfonyl)-γ-cyclodextrin Poly-β-cyclodextrin [Cross-linked by Epichlorohydrin] 5,10,15,20-Tetrakis[3,5-bis(per-O-methyl-α-cyclodextrin-6-yloxy)phenyl]-21H,23H-porphine 5,10,15,20-Tetrakis[4-(per-O-methyl-α-cyclodextrin-6-yloxy)phenyl]-21H,23H-porphine Triacetyl-β-cyclodextrin Trimethyl-β-cyclodextrin 1,1,1-Tris[4-(per-O-methyl-α-cyclodextrin-6-yloxy)phenyl]ethane
References 1) Calixarene A. Ikeda, S. Shinkai, . 1997, , 1713; M. Ayabe, S. Shinkai, 2) Cyclodextrin K. Takahashi, . 1998, , 2013. 3) Thiacalixarene 2004, number N. Morohashi, S. Miyano, , 2.
280
2003, number
Availability, price or specification of the listed products are subject to change without prior notice.
, 2.
5g 1g 1g 25g
200mg
1g
25g 5g 25g 5g 250g 1g 1g 10mg 1g 1g 1g 1g 200mg 200mg 5g 10mg 10mg 25g 1g 10mg
Diacetylene Monocarboxylic Acids for LB Films
Diacetylene Monocarboxylic Acids for LB Films Recently, the Langmuir-Blodgett Method1) is receiving much attention as a means to obtaining functional organic super thin films in the electric field. This method can control rearrangement in molecular dimensions while retaining highly orderly structure. New diversified applications utilizing the method are being developed in a variety of fields such as molecular electronics, bioelectronics, etc.2) Amphiphilic diacetylene monocarboxylic acids are readily polymerised by heat, light3) and radiation while polymerized films3,4) are thermally and mechanically stable. As a result, application to photoresist material5) having a high degree of resolving power and nonlinear optical material6) are expected.
Diacetylene Monocarboxylic Acids CH3(CH2)m-1
C C C C
m=4,10,12,14,16
(CH2)n
COOH
n=0,8
Product No. Product Name H0668 H0666 H0667 H0775 N0514 N0515 P1030 P1032 T1200
Unit Size
2,4-Heneicosadiynoic Acid 10,12-Heptacosadiynoic Acid 2,4-Heptadecadiynoic Acid 10,12-Heptadecadiynoic Acid 10,12-Nonacosadiynoic Acid 2,4-Nonadecadiynoic Acid 10,12-Pentacosadiynoic Acid 2,4-Pentadecadiynoic Acid 10,12-Tricosadiynoic Acid
100mg 100mg 500mg 100mg 100mg 100mg 100mg 100mg 1g 100mg 100mg 1g
(m=16, n=0) (m=14, n=8) (m=12, n=0) (m=4, n=8) (m=16, n=8) (m=14, n=0) (m=12, n=8) (m=10, n=0) (m=10, n=8)
Related Compounds Product No. Product Name B1298 B1342 B1340 B1348 C1195 H0619 H0663 P1065 N0718 O0193 O0192 P1053 P1054 P1055 P0497 T1211 T1239 T1123 U0054 U0055
Unit Size
1,4-Bis(trimethylsilyl)-1,3-butadiyne 1-Bromo-4,6-nonadecadiyne 1-Bromo-10,12-pentacosadiyne 1-Butynyl Iodide (stabilized with Copper chip) 3-Chloro-1-butyne 2,4-Hexadiyne-1,6-diol 2,4-Hexadiyne-1,6-diol Bis(azobenzene-4-sulfonate) 1-Iodo-1-propyne 4,6-Nonadecadiyn-1-ol 1-Octadecyl-4-(4-phenyl-1,3-butadienyl)pyridinium Bromide N-Octadecyl-4-stilbazole Bromide 10,12-Pentacosadiyn-1-ol 1-(10,12-Pentacosadiynyl)pyridinium Bromide 1-Pentynyl Iodide Propiolic Acid 22-Tricosenoic Acid Trimethylsilylacetylene 1-(Trimethylsilyl)-1-propyne 10-Undecynoic Acid 10-Undecyn-1-ol
1g
1g 1g 1g
100mg
5g 100mg 5ml 25ml 5ml 25ml 1g
5g 100mg 100mg 5g 5g 5g 100mg 1g 500mg 1g 1g 1g 100mg 1g 25g 1g 250ml 100ml 5g 5g
References 1) K. Blodgett, 2) a) M. Sugi, c) K. Hukuda,
., in
3) a) B. Tieke, Barraud, 4) a) D. Day, 5) a) A. Barraud, , 317. 6) a) F. Kajzar,
. 1935, , 1007. 1983, , 567; b) M. Sugi, , CMC, 1986; d) Review: 1986, . . 1976, , 764; b) B. Tieke, . 1977, , 509; d) G. Lieser, 1980, , 1478; b) I. R. Perterson, 1979, , 120; b) A. Barraud, . 1983,
1985,
, 133; b) P. A. Chollet,
1986,
1980, 1983,
1985,
1985, , 102; ; e) Review: . 1977, , 521; c) A. , 77. , 252. 1980, , 91, 99; 1983, , 1; c) F. Kajzar,
, 11.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
281
Reagents for High-Performance Polymer Research
Reagents for High-Performance Polymer Research Polyvinyl chloride and polyethylene polymers, which have long been the mainstay of industrial polymers, are now making way for new high performance polymers. Engineering plastics are polymers that have various properties designed into the polymer. For example, some polymers are designed for thermal resistance, such as polyamide, and polycarbonate, which are widely used these days. The thermal resistance of a polymer is determined by the softening point, as the softening point rises with the increase in the material strength. To make improvements in the softening points and material strength, the super engineering plastics such as polysulfone, polyether sulfone, polyarylate and polyimide have been developed. The softening points of these polymers are all above 150 ºC, and these utilized in materials of fireman uniform and bulletproof vest, and so on. Active R&D is continuing to take place to further improve the performance.1) On the other hand, there have been active experiments in adding new functions to the polymers, such as the electrical, optical, medical and biological properties. For example, copolymers which are obtained by the polymerization of fluorine containing monomers and variety of monomers have been utilized as photoresists, optical fiber dressings, oxygen enrichment membranes, and membrane oxygenators. Polysilane has the maximum absorption in the ultraviolet region, and also has photosensitivity; therefore, it can be used as a positive type resist with excellent oxygen plasma resistance.2) Polylactic acid (PLA) has been commercialized as an environmentally-friendly polymer, being compatible with the natural environment. Furthermore, it can save fossil resources as it is made of biomass raw materials.3) Further broad applications are expected to be made with functional polymers, thus R&D in this field is highly promising. The page below shows a wide variety of monomers and intermediates as building blocks for functional polymers. These are surely useful for the development of novel polymers. A1322
A1251
COCH3 O2N
CH3
Biphenyls
B0813
B0464
A1340
B1181
NH2
B1308
NH2
B2854
OH HO
OH
NC
CN
Cl
O
O
C
C Cl
O
O
H C
C H
HO
D0864
B1191
B2623
B1664
B1165
O C OH
O
O O HO C
O C OH
HOCH2
CH2OH
S OH
HO S O
. xH2O
O
ClO2S
SO2Cl
HO C O
B2285
B1326 O
O
O
B1711
B1921
B2099
O
SH O
HS
B1671
H2N
O
O
NH2
BrCH2
CH2Br
ClCH2
CH2Cl
O
B3648
D2266
D1550
D1902
F3C O
H2N
NH2
I
Br
CH3 C O
O O C CH3
O
O
CH3 C HN
NH C CH3
CF3
282
Availability, price or specification of the listed products are subject to change without prior notice.
O CH3 C
O C CH3
Reagents for High-Performance Polymer Research
D0077 H2N
D0078 H2N
NH2
H2N
D1632
NH2
NH2
H2N
NH2
F
F
F
F
OCH2CH3
D2315
F
OCN
NCO
D1777
F
CH3O C
F
OH NH2
F
H3C CH3
CH3 N CH3 F
F
F
D0826
D0878
D1519 F
F
F
F
O C OCH3
O2N
NO2
NH
NH
HO
OH F
Product No. Product Name A1322 A1251 A1340 B0813 B0464 B1181 B1308 B2854 D0864 B1191 B2623 B1664 B1165 B2285 B1326 B1671 B1921 B2099 B1711 B3648 D2266 D1550 D1902 D0077 D0078 D1632 D1695 D1696 D1127 B0831 D2180 D2181
F
H2N
O2N NO2 O
F
D1717
OCH3 O2N F
B1309
F
Br
HO
F
D2263
CH3O
F
D2312
F
CH3
F
F
Br
F
D2330
CH3
I
Br
D2181
O C OCH2CH3
O CH3CH2O C
Br
F
D2180
D2051
I
F
F
F CH3CH2O
D1696
F NH2
F
B0831
F
H2N
. 4HCl . 2H2O
D1127
D1695
4-Acetyl-4'-methylbiphenyl 4-Amino-4'-nitrobiphenyl 4-Amino-p-terphenyl 2,2'-Biphenol 4,4'-Biphenol 4,4'-Biphenyldicarbonitrile 4,4'-Biphenyldicarbonyl Chloride 4,4'-Biphenyldicarboxaldehyde 2,2'-Biphenyldicarboxylic Acid 4,4'-Biphenyldicarboxylic Acid 4,4'-Biphenyldimethanol 4,4'-Biphenyldisulfonic Acid 4,4'-Biphenyldisulfonyl Chloride 4,4'-Biphenyldithiol 4,4'-Biphthalic Anhydride 4,4'-Bis(4-aminophenoxy)biphenyl 4,4'-Bis(bromomethyl)biphenyl 4,4'-Bis(chloromethyl)biphenyl 2,2'-Bis(trifluoromethyl)benzidine 4-Bromo-4'-iodobiphenyl 4,4'-Diacetoxybiphenyl N,N '-Diacetylbenzidine 4,4'-Diacetylbiphenyl 3,3'-Diaminobenzidine 3,3'-Diaminobenzidine Tetrahydrochloride Hydrate 4,4'-Diaminooctafluorobiphenyl 4,4'-Dibromobiphenyl 4,4'-Dibromooctafluorobiphenyl 4,4'-Diethoxybiphenyl Diethyl 4,4'-Biphenyldicarboxylate 3,3'-Difluorobiphenyl 4,4'-Difluorobiphenyl
F
F
F
Unit Size 1g
1g 5g 25g 25g 1g 1g 25g 5g 5g 5g
10g 1g 25g 5g 5g 25g 10g 5g 5g 25g 1g 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 5g 25g 500g 500g 5g 10g 5g 250g 25g 5g 25g 25g 1g 25g 25g 5g 500g 25g 25g 500g 1g 25g 25g 25g 5g 250g 5g 5g 5g 1g 5g
283
Reagents for High-Performance Polymer Research
Product No. Product Name D2312 D2315 D2051 D2330 D2263 D1717 B1309 D1777 D0826 D0878 D1519
Unit Size
3,3'-Dihydroxybenzidine 4,4'-Diiodobiphenyl 4,4'-Diisocyanato-3,3'-dimethylbiphenyl 4,4'-Dimethoxyoctafluorobiphenyl 4-Dimethylamino-4'-nitrobiphenyl 2,2'-Dimethylbiphenyl Dimethyl 4,4'-Biphenyldicarboxylate 2,2'-Dinitrobiphenyl 4,4'-Dinitrobiphenyl N,N '-Diphenylbenzidine Octafluoro-4,4'-biphenol
5g 25g 25g 1g 1g 1g 5g 5g
B1823
B0483
Cl
B1109 O
O
N
CH2
O
NH2
CH3
H2N
CH2
CH3
N
CH3
CH2
CH3
N
CH3
NH2 H2N
CH2
N H3CH2C O
M0220
NH2
NH2
CH2
O CH2CH3
D1684
H2N
H3C O
N
Cl
D1683
CH3
N
O CH3
CH2 Cl
D2046
B1971
Cl
H2N
Diphenylmethanes
25g 250g 250g 5g 5g 5g 25g 25g 5g 25g 5g
H2N
CH2
CH2
NH2
O
D1925
D1939
D1940
B0819
OH F
CH2
HO
CH2
F
D2711
HO
HO
CH2
OH HO
CH2
OH
C
HO
D2097
D0833
CH3
M0217 (CH3)3C
CH3
OCN
CH2
M0215
NCO
O2N
CH2
OH
HO
C(CH3)3
M0214 OH
HO CH2
HO
Cl
Cl
M1684
CH2
(CH3)3C
OH C(CH3)3
D0897
CH3
HO
CH2
CH3
HO
OH
OCN
CH2
NCO
CH2
OH CH2
284
NH2
Availability, price or specification of the listed products are subject to change without prior notice.
HO CH2
NH2 CH2CH3
C OH
HO
OH
CH3
O
HO C
CH2
M1134
M0221
CH3 CH2
CH3CH2
Cl
Cl H2N
CH2CH3
CH3
OH H2N
CH3
O CH3
C(CH3)3
M1238
CH3
C(CH3)3
HO
CH3CH2
CH3
M1099
(CH3)3C
OH CH2
CH3
M0213
(CH3)3C
CH2
NO2
M0609
CH3
CH3
Reagents for High-Performance Polymer Research
Product No. Product Name B1823 B0483 B1971 B1109 D2046 D1683 D1684 M0220 D1925 D1939 D1940 B0819 D2711 D2097 D0833 M0217 M0215 M0609 M0213 M0214 M1099 M1238 M1134 M1684 D0897 M0221
Unit Size
Bis(4-amino-2,3-dichlorophenyl)methane Bis[4-(dimethylamino)phenyl]methane Bis(3-ethyl-5-methyl-4-maleimidophenyl)methane 4,4'-Bismaleimidodiphenylmethane 4,4'-Diamino-3,3'-dimethyldiphenylmethane 3,3'-Diaminodiphenylmethane 3,4'-Diaminodiphenylmethane 4,4'-Diaminodiphenylmethane 4,4'-Difluorodiphenylmethane 2,2'-Dihydroxydiphenylmethane 2,4'-Dihydroxydiphenylmethane 4,4'-Dihydroxydiphenylmethane 4,4'-Dihydroxytetraphenylmethane 4,4'-Diisocyanato-3,3'-dimethyldiphenylmethane 4,4'-Dinitrodiphenylmethane 2,2'-Methylenebis(6-tert-butyl-p-cresol) 2,2'-Methylenebis(6-tert-butyl-4-ethylphenol) 4,4'-Methylenebis(2-chloroaniline) 2,2'-Methylenebis(4-chlorophenol) 4,4'-Methylenebis(2,6-di-tert-butylphenol) 4,4'-Methylenebis(2,6-dimethylphenol) 4,4'-Methylenebis(2-ethyl-6-methylaniline) 2,2'-Methylenebis(4-methylphenol) 4,4'-Methylenebis(2-methylphenol) Methylenediphenyl 4,4'-Diisocyanate Methylenedisalicylic Acid (mixture of isomers)
1g
25g 25g
B0084
B1741
O
H2N O
C OH O
C
Benzophenones
O C OH
C
O
B1267 O
B1433
D1682
O O
O
O
CH3
S
CH3NH
O
C
C OH
NH2
O
O
C
NHCH3
H2N
C
C
NH2
O
O
D0230
D1621
D1796
Cl Cl
C
D0577
F
Cl
C
Cl
C
C
F
C
OCH3
C
D1688
C
NO2
O2N
O CH3O
HO O
HO O
OCH3
OH
D0765
OH
OH O
OH CH O 3
F
C
D0586
OH
O
F
D1099
O
O
D0575
C
D1797
O
O
HO
Bz
O
D1561
H2N
C
O HO C
. H2O
Cl
B0948
5g 25g
1g 5g 5g 1g 1g 25g 25g 25g 25g 25g 25g
A1128 Cl
25g 500g 500g 500g 25g 5g 25g 500g 25g 5g 5g 25g 25g 5g 5g 500g 500g 500g 500g 500g 500g 25g 25g 25g 500g 500g
25g 25g 25g
O OCH3
C
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
285
Reagents for High-Performance Polymer Research
T0118
T1371
OH
T0584
HO
HO C
C
OCH3 O
O
O OH HO
CH3O
HO
HO
O HO
T2028
OH HO
OH
C
C
OCH3
Product No. Product Name A1128 B0084 B1741 B0948 B1267 B1433 D1682 D1561 D0230 D1621 D1796 D1797 D1099 D0577 D0575 D0586 D0765 D1688 T0118 T1371 T0584 T2028
Unit Size
2-Amino-2',5-dichlorobenzophenone Benzophenone-2,4'-dicarboxylic Acid Monohydrate Benzophenone-4,4'-dicarboxylic Acid 3,3',4,4'-Benzophenonetetracarboxylic Dianhydride 4-Benzoyl 4'-Methyldiphenyl Sulfide 4,4'-Bis(methylamino)benzophenone 3,3'-Diaminobenzophenone 4,4'-Diaminobenzophenone 2,4'-Dichlorobenzophenone 4,4'-Dichlorobenzophenone 2,4'-Difluorobenzophenone 4,4'-Difluorobenzophenone 2,2'-Dihydroxybenzophenone 4,4'-Dihydroxybenzophenone 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone 2,2'-Dihydroxy-4-methoxybenzophenone 4,4'-Dimethoxybenzophenone 3,3'-Dinitrobenzophenone 2,2',4,4'-Tetrahydroxybenzophenone 2,3',4,4'-Tetrahydroxybenzophenone 2,4,4'-Trihydroxybenzophenone 2,2',4-Trimethoxybenzophenone
25g
1g 25g 25g 5g 25g 10g 25g
25g 5g
5g
D0041
D2285
H2N
Diphenylamines
D1556
NH
D0812
N2
HSO4
286
N2 HSO4
D1512
D0609 D0906
NH
OCH3
NH
NH
NH
CH3
NH
NH
M1173
H N
NH
CH3
CH3
Product No. Product Name D0041 D2285 D2290 D1556 D0632 D0812
NH
CH3 CH3O
D0950
CH3O
OCH3
OH NH
CH3
NH2
D2290
. H2SO4 . xH2O
D0632
HO
NH
10g 25g 25g 500g 10g 1g 5g 1g 500g 500g 25g 500g 25g 500g 25g 25g 500g 25g 25g 5g 10g 25g
4,4'-Diaminodiphenylamine Sulfate Hydrate 4-Diazo-3-methoxydiphenylamine Sulfate 4-Diazo-4'-methoxydiphenylamine Sulfate 3,3'-Dihydroxydiphenylamine 4,4'-Dimethoxydiphenylamine N,N '-Di-2-naphthyl-1,4-phenylenediamine
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 25g
1g 25g
500g 25g 25g 1g 5g 500g
Reagents for High-Performance Polymer Research
Product No. Product Name
Unit Size
N,N '-Diphenyl-1,4-phenylenediamine N,N '-Diphenyl-1,4-phenylenediamine m,m '-Ditolylamine p,p '-Ditolylamine 4-Methyldiphenylamine
D0609 D0906 D1512 D0950 M1173
25g 25g 5g 5g 1g
C1069
B1370
B1680
H2N
Cl
Diphenyl Ethers
B1243
B0834
O
NH2
B1646
O
O
NH2
Br
O
NH2 O
Br
B1454
O
O
O
HO
C2335
CH3O
CH3O
O
O
O
O
HO
O
D2115
O
H2N
O
H2N
O
D0832
O
NH2
D2017
Br
Br
Cl Br
D2150
Br
HO C
Br
O Br
Br
Br
D2121 OH
NH2
OH
OCH3
OCH3
O0088
O
D1388
Br
D1924
O
NH2
CH2OH
B1486
OH
O
CH2OH
Br HO
O
B1484
CHO
B1485
H2N
O
B1643 CHO
H2N
500g 500g 25g 25g 5g
HO
O O
C OH
O0298
HO
O
O
OH
O0237 O
O O
O2N
O
NO2
O
O
ClO2S
O
SO2Cl
O O
Product No. Product Name C1069 B1370 B1680 B1243 B0834 B1646 B1643 B1484 B1485 B1454 B1486 C2335 D1388 D1924
4-Amino-4'-chlorodiphenyl Ether 1,3-Bis(3-aminophenoxy)benzene 1,3-Bis(4-aminophenoxy)benzene 1,4-Bis(4-aminophenoxy)benzene Bis(4-bromophenyl) Ether Bis(2-formylphenyl) Ether 2,2'-Bis(hydroxymethyl)diphenyl Ether 1,3-Bis(4-hydroxyphenoxy)benzene 1,4-Bis(3-hydroxyphenoxy)benzene 1,3-Bis(4-methoxyphenoxy)benzene 1,4-Bis(3-methoxyphenoxy)benzene 4-Chloro-4'-hydroxydiphenyl Ether Decabromodiphenyl Ether 3,4'-Diaminodiphenyl Ether
O O
Unit Size 5g
1g 1g 1g
5g 25g 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 25g 25g 25g 25g 10g 5g 5g 1g 5g 5g 25g 500g 25g
287
Reagents for High-Performance Polymer Research
Product No. Product Name O0088 D2115 D2150 D2121 D0832 D2017 O0298 O0237
Unit Size
4,4'-Diaminodiphenyl Ether 4,4'-Dicarboxydiphenyl Ether 2,2'-Dihydroxydiphenyl Ether 4,4'-Dihydroxydiphenyl Ether 4,4'-Dinitrodiphenyl Ether 1,4-Diphenoxybenzene 4,4'-Oxybis(benzenesulfonyl Chloride) 4,4'-Oxydiphthalic Anhydride
25g
500g 25g 1g 500g 10g 25g 25g 25g
25g 1g 5g
B1267
T0632
B0850 OH
CH3
Diphenyl Sulfides
S
Bz
H2N
S
Cl S
NH2
Cl
B1527
HO
D1356
S CH3
OH
HO
B1662
S
OH
CH3
P0230
T1427
D0847
O CH2 C C S CH3
O S C C CH2 CH3
S
T0865 Cl
B3484
CH3 O 2N
S
HS
S
S
NO2
T0208 OH
HO
Cl
O
O C OH
S
SH
HO
Cl
S
OH
Cl
Product No. Product Name B1267 T0632 B0850 B1527 D1356 B1662 D0847 B3484 P0230 T1427 T0865 T0208
Unit Size
4-Benzoyl 4'-Methyldiphenyl Sulfide Bis(4-aminophenyl) Sulfide Bis(2-hydroxy-5-chlorophenyl) Sulfide Bis(4-hydroxy-3-methylphenyl) Sulfide Bis(4-hydroxyphenyl) Sulfide Bis(4-methacryloylthiophenyl) Sulfide Bis(4-nitrophenyl) Sulfide 4-tert-Butyldiphenyl Sulfide Phenyl Sulfide 4,4'-Thiobisbenzenethiol 2,2'-Thiobis(4,6-dichlorophenol) 5,5'-Thiodisalicylic Acid
25g 25g 5g 25g 25g 25g 5g
B2859 NH2
H2N O
O
288
HO
10g 25g 25g 500g 500g 25g 25g 100g 500g 5g 500g 25g
B1681
H2N
Diphenyl Sulfones
C CH3 CH3
HO C
S
HO
S
OH
O
O
Availability, price or specification of the listed products are subject to change without prior notice.
S
O
O NH2
Reagents for High-Performance Polymer Research
B1682
B0394
D0089
D0536
H2N H2N
O
O2N
O
O S
O
S
NH2
O
O
O H2N
NH2 F
S
F
S
O
O
O NO2
NH2
B1572
D0537 Br HO(CH2)2O Br
O(CH2)2OH
F
O
F HO
S
O
Cl
S
Cl
O
S O
CH3
CH3 H2N
S O
D0916
O
O
O
HO C
S
C OH
NH2
O
O
D2309
NaO3S
SO3Na
O
O SO2
O
O
O
S O
O
O
Product No. Product Name B2859 B1681 B1682 B0394 D0089 D0536 B1572 D0537 B1577 B0495 B1590 D1927 T1419 D2367 B0810 P0231 D0916 D2309
Unit Size
Bis(3-amino-4-hydroxyphenyl) Sulfone Bis[4-(3-aminophenoxy)phenyl] Sulfone Bis[4-(4-aminophenoxy)phenyl] Sulfone Bis(3-aminophenyl) Sulfone Bis(4-aminophenyl) Sulfone Bis(4-fluoro-3-nitrophenyl) Sulfone Bis[3,5-dibromo-4-(2-hydroxyethoxy)phenyl] Sulfone Bis(4-fluorophenyl) Sulfone Bis(4-hydroxy-3,5-dimethylphenyl) Sulfone Bis(4-hydroxyphenyl) Sulfone Bis[4-(2-hydroxyethoxy)phenyl] Sulfone Bis(4-nitrophenyl) Sulfone 3,7-Diamino-2,8-dimethyldibenzothiophene Sulfone (contains 2,6-Dimethyl isomer) 4,4'-Dicarboxydiphenyl Sulfone 4,4'-Dichlorodiphenyl Sulfone Diphenyl Sulfone Diphenylsulfone-3,3'-disulfonic Acid Disodium Salt 3,3',4,4'-Diphenylsulfonetetracarboxylic Dianhydride
B1286
O
Bisphenol A type Compounds
OH
D2367
NO2
S O
P0231
O
O2N
S O
CH3
T1419
O
O(CH2)2OH
OH HO
CH3
D1927
O S O
O
S O
O
B1590
B0810
CH3
O
Br
HO(CH2)2O
B0495
CH3
Br O S O
B1577
CH3 C O
5g 25g 25g 500g 500g 10g 500g 250g 500g 500g 500g 25g 25g 25g 500g 500g 25g 25g
25g 25g
10g
25g 25g 25g 25g 25g
25g 25g 5g
B1551
CH3 C CH3
O O C CH3 H2N
CH3 O
C
O
NH2
CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
289
Reagents for High-Performance Polymer Research
B1562
B2748
CH3 H2N
C
CH3 C
CH3
CH3
CH3
NH2
CH3CH2
B1335
HC
CH CH3
HO
C
B1251
CH3 CH2CH3
Cl
O
CH3
C O
C
OH
CH3
O O C Cl
NCO
C
CH3
B2749
B1796
OCN
CH3
CH3
B2750
B1850 CH3
CH3 CH2O
CH3 HO
C
OH
C
OCH2
CH3
O
O
HO
C
B1464
B2751
CH3
CH3
CH3
CH3 C
OH
CH3
B1567
HC
CH CH3
HO
CH3 CH3
C
CH3
CH3
C
C
CH3
CH3
OH
CH3
CH3
OH
CH3
C
C
CH3
CH3
HO
C
HO
CH3 HO
OH
CH2 C C O CH3
T0851
C
OH
CH2CH3
I0356
O
C CH3
T0032
OH
I0389
CH3 OH
CH3 CH3 CH3
B0494
CH3
B1050
CH3
CH3
CH3
CH3
B1563
HO
OH
CH3 CH3
CH3
CH3
HO
HO
CH3
CH3 C
O
O O C C CH2 CH3
CH3
HO C CH2O
CH3 C
O OCH2 C OH
CH3
T1428 OH
Br
Br Br
CH3 HO
OH
C
HO(CH2)2O
CH3 Br
Br
CH3 C CH3
Br O(CH2)2OH
HO
Br
CH3 C
C CH3
CH3
Br OH
Product No. Product Name B1286 B1551 B1562 B2748 B1335 B1251 B2749 B1796 B2750 B1850 B1464 B2751 B1567 B1050 B1563 B0494 I0389 I0356 T0032 T0851 T1428
290
2,2-Bis(4-acetoxyphenyl)propane 2,2-Bis[4-(4-aminophenoxy)phenyl]propane α,α'-Bis(4-aminophenyl)-1,4-diisopropylbenzene 2,2-Bis(3-sec-butyl-4-hydroxyphenyl)propane 2,2-Bis(4-chloroformyloxyphenyl)propane 2,2-Bis(4-cyanatophenyl)propane 2,2-Bis(3-cyclohexyl-4-hydroxyphenyl)propane 2,2-Bis(4-glycidyloxyphenyl)propane 2,2-Bis(2-hydroxy-5-biphenylyl)propane α,α'-Bis(4-hydroxy-3,5-dimethylphenyl)-1,4-diisopropylbenzene 2,2-Bis(4-hydroxy-3,5-dimethylphenyl)propane 2,2-Bis(4-hydroxy-3-isopropylphenyl)propane 2,2-Bis(4-hydroxy-3-methylphenyl)propane 2,2-Bis(4-hydroxyphenyl)butane α,α'-Bis(4-hydroxyphenyl)-1,4-diisopropylbenzene 2,2-Bis(4-hydroxyphenyl)propane 4,4'-Isopropylidenediphenol Dimethacrylate 4,4'-Isopropylidenediphenoxyacetic Acid Tetrabromobisphenol A Tetrabromobisphenol A Bis(2-hydroxyethyl) Ether α,α,α'-Tris(4-hydroxyphenyl)-1-ethyl-4-isopropylbenzene
Unit Size 25g 25g 25g 1g
25g 25g
25g 5g 25g 25g 5g 25g 25g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
500g 250g 500g 25g 5g 10g 25g 500g 5g 500g 25g 25g 500g 25g 500g 500g 25g 25g 500g 500g 25g
Reagents for High-Performance Polymer Research
B1415
B1397
H2N
NH2
H2N
CF3 HO
Bisphenol AF type Compounds
B1704 H2N
NH2
CF3 H2N
C
OH
O
C
NH2
HO C
C
CH3
B0945
H2N
O
O C OH
HO
CF3 C CF3
O
NH2
B1509
CF3
CF3 C
CF3
C
CF3
CF3
CF3
CH3
CF3
B1401
CF3
NH2 CF3
C CF3
B1400
B1398
OH OCN
C
NCO
CF3
CF3
H0771 O
O
CF3 C
O
O
CF3
O
O
Product No. Product Name B1415 B1397 B1398 B1704 B1400 B1401 B0945 B1509 H0771
Unit Size
2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane 2,2-Bis(3-amino-4-methylphenyl)hexafluoropropane 2,2-Bis[4-(4-aminophenoxy)phenyl]hexafluoropropane 2,2-Bis(3-aminophenyl)hexafluoropropane 2,2-Bis(4-aminophenyl)hexafluoropropane 2,2-Bis(4-carboxyphenyl)hexafluoropropane 2,2-Bis(4-hydroxyphenyl)hexafluoropropane 2,2-Bis(4-isocyanatophenyl)hexafluoropropane 4,4'-(Hexafluoroisopropylidene)diphthalic Anhydride
5g 5g 5g 5g 5g 5g 5g 5g
B1317
B0948 B1726 O
O
B1326
O
O
25g 25g 25g 25g 25g 25g 25g 1g 25g
O
O
O
C
C2262
O
O
C0857
O
O
O
Aromatic Tetracarboxylic Dianhydrides
D2192
O
O
O O
O
O
O
O
O
O
H0771 O
CF3 C
O O
O
CF3
O
O
O
O
O
SO2 O
O
O
O
O
O
CH3
O
P0972
O
O
O
O
O
O0237
N0369 N0755
O
D2309
O
O
O
O
O
O
O
O
O
D1901
O
O
O
O
O
B0040
O
O
O
O
O
O
O
O
O O
O
O
O
O
O
O O
O O
O O
O
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
291
Reagents for High-Performance Polymer Research
Product No. Product Name B0948 B1726 B1317 B1326 C2262 C0857 D2192
Unit Size
3,3',4,4'-Benzophenonetetracarboxylic Dianhydride 3,3',4,4'-Benzophenonetetracarboxylic Dianhydride Bicyclo[2.2.2]oct-7-ene-2,3,5,6-tetracarboxylic Dianhydride 4,4'-Biphthalic Anhydride 1,2,3,4-Cyclobutanetetracarboxylic Dianhydride 1,2,3,4-Cyclopentanetetracarboxylic Dianhydride 4-(2,5-Dioxotetrahydrofuran-3-yl)-1,2,3,4-tetrahydronaphthalene-1,2-dicarboxylic Anhydride 5-(2,5-Dioxotetrahydrofuryl)-3-methyl-3-cyclohexene-1,2-dicarboxylic Anhydride 3,3',4,4'-Diphenylsulfonetetracarboxylic Dianhydride 4,4'-(Hexafluoroisopropylidene)diphthalic Anhydride Naphthalene-1,4,5,8-tetracarboxylic Dianhydride Naphthalene-1,4,5,8-tetracarboxylic Dianhydride (purified by sublimation) 4,4'-Oxydiphthalic Anhydride 3,4,9,10-Perylenetetracarboxylic Dianhydride Pyromellitic Dianhydride
D1901 D2309 H0771 N0369 N0755 O0237 P0972 B0040
D2704
D2469
Dichlorosilanes (for Polysilanes)
D2348
D1976
D2710
D0362
Cl
Cl Si
Cl
Cl
D2144
Cl
Cl
Product No. Product Name
292
Dibutyldichlorosilane Di-tert-butyldichlorosilane Dichlorocyclohexylmethylsilane Dichlorodecylmethylsilane Dichlorodiethylsilane Dichlorodihexylsilane
CH3 CH3
Cl
Si
CH3
Cl
O0264
Cl CH3(CH2)17 Si CH3 Cl
Cl
T1590
CH3 CH3 Cl
Cl
CH3
CH3(CH2)5 Si CH3
Cl
Si CH3
Si CH3 Cl
Cl
Cl
Cl
Cl CH3(CH2)7 Si CH3
Cl
H0855
CH3(CH2)11 Si CH3
P0790
Cl
D0358
Si CH3
D2349
CH3(CH2)4 Si (CH2)4CH3
O0265
CH3
Si (CH2)5CH3 Cl
Cl
Cl
D2704 D2469 C1399 D2348 D1976 D2712
CH3(CH2)5
25g 25g
CH3
D2603
Cl
CH3CH2 Si CH2CH3
5g 25g 1g
10g
H3C Cl CH3
D2712
25g 500g 25g 25g 250g 5g 25g 500g 500g
25g
C1399
H3C C Si C
Cl
Cl
Cl CH3(CH2)9 Si CH3
Si (CH2)3CH3
500g 500g 500g 25g 5g 25g
1g 5g
H3C Cl CH3
Cl CH3(CH2)3
25g 25g 25g
Si
Si Cl
CH3 CH3
Cl Cl CH3
Si Si CH3 Cl Cl
Unit Size 5g 5g
5g 5g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
25g 25g 25g 25ml 25g 25g
Reagents for High-Performance Polymer Research
Product No. Product Name
Unit Size
D2603 D0358 D2710 D0362 D2349 H0855 O0264 O0265 P0790 D2144 T1590
5g 25ml 5g 25g
Dichlorodiisopropylsilane Dichlorodimethylsilane Dichlorodipentylsilane Dichlorodiphenylsilane Dichlorododecylmethylsilane Dichlorohexylmethylsilane Dichloro(methyl)octadecylsilane Dichloro(methyl)-n-octylsilane Dichloro(methyl)phenylsilane 1,2-Dichlorotetramethyldisilane 1,1,2,2-Tetrachloro-1,2-dimethyldisilane
25g 5g 5g
B0767
C0702
Lactones & Lactides
L0115
H0168
O
O
CH3
CH3
O
O
O
O
O
O
L0091
O
O
O
O
CH3
CH3
O
O
V0039
O O
Product No. Product Name
Unit Size
γ-Butyrolactone ε-Caprolactone DL-Lactide L-(-)-Lactide β-Propiolactone δ-Valerolactone
B0767 C0702 L0091 L0115 H0168 V0039
25ml 25ml
500ml 500ml 25g 250g 25g 500g
25g 5g 25g
G0196
H0228
HO
L0226
OH
O
Hydroxycarboxylic Acids
25g 500ml 25g 500g 25ml 25ml 25ml 25ml 250g 25g 25g
OH
CH3
O
O
CH3
OH
OH OH
L0165 O CH3
OH OH
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
293
Reagents for High-Performance Polymer Research
Product No. Product Name G0196 H0228 L0226 L0165
Unit Size
Glycolic Acid DL-3-Hydroxybutyric Acid (contains Polymolecular esterification product) DL-Lactic Acid L-Lactic Acid
25g 5g 25g 25g
A1988
B2935 O
CH3
Diacrylates & Dimethacrylates
B2937
O
O O
O
O
B2340
O
O
O
CH2 CH C O(CH2)4O C CH CH2
B2863
O
O
CH2
OH
CH2
B2936
500g 25g 500g 500g
O
O
O
CH2 CH C O(CH2)10O C CH CH2 CH2 CH C O(CH2)6O C CH CH2 CH2 CH C OC9H18O C CH CH2
CH2 CH C OCH2(CF2)4CH2O C CH CH2
B1065
E0102
D1530 O
CH2
CH3 O O
B2938
O
O
O
O O
CH2
O OH
CH3
O
CH3
O 4
CH2 CH C O(C3H6O)2 C CH CH2
O O
CH3
H3C O
C CH CH2 CH 2
CH3
O
CH2
O
N0780
T1352
CH3
CH3
T0948
CH2 CH C O CH2CH2O
O
O O CH3 O CH3 O O CH3 CH CH C OCH CCH O C CH CH CH C C OCH CCH O C C CH CH C C O 2 2 2 2 2 2 2 2 2
CH2
T1569
O
CH2
N0790
CH3
294
O CH3
CH3
CH3
CH2
O
O
CH2 CH2
O
D3470
CH3
CH3
O CH2CH2O n C C CH2 CH3
T2389
O CH3
O
O
C C (OCH2CH2)3O C C CH2 CH2 CH C O(C3H6O)3 C CH CH2
Product No. Product Name
Unit Size
A1988 B2935 B2937 B2936 B2863 B2340 B1065 D1530 D3470 E0102 B2938 N0790 N0780 T1352
25g 25g 25g 25g 25g 1g 25ml 25ml 25g 25ml 25g 25g 25g 25g
1-(Acryloyloxy)-3-(methacryloyloxy)-2-propanol (stabilized with MEHQ) 1,4-Bis(acryloyloxy)butane (stabilized with MEHQ) 1,10-Bis(acryloyloxy)decane (stabilized with MEHQ) 1,6-Bis(acryloyloxy)hexane (stabilized with MEHQ) 1,9-Bis(acryloyloxy)nonane (stabilized with MEHQ) 1,6-Bis(acryloyloxy)-2,2,3,3,4,4,5,5-octafluorohexane 1,3-Butanediol Dimethacrylate (stabilized with MEHQ) Diethylene Glycol Dimethacrylate (stabilized with MEHQ) Dipropylene Glycol Diacrylate (stabilized with MEHQ) Ethylene Glycol Dimethacrylate (stabilized with HQ) Glycerol Dimethacrylate (mixture of 1,2- and 1,3-form) (stabilized with MEHQ) Neopentyl Glycol Diacrylate (stabilized with MEHQ) Neopentyl Glycol Dimethacrylate (stabilized with MEHQ) Polyethylene Glycol Dimethacrylate n≒4 (stabilized with MEHQ)
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
500g 500g 500g 500g 500g 5g 500ml 500ml 500g 500ml 500g 500g 500g 500g
Reagents for High-Performance Polymer Research
Product No. Product Name
Unit Size
T1569 T0948 T2389
25g 25ml 25g
Tetraethylene Glycol Diacrylate (stabilized with MEHQ) Triethylene Glycol Dimethacrylate (stabilized with MEHQ) Tripropylene Glycol Diacrylate (stabilized with MEHQ)
A1019
D0605
500g 500ml 500g
B1505 SH
H2N
Related Compounds
CH
CH2
HOCH2
CH2OH SH
B2076
B1549
B1499
B1336
B2752
Cl
H2N
NH2
HO O HO C
H2N
OH
O O(CH2)10O
N
C OH
N
NH2 Cl
B1500
B1403
B1419
F0447
OH CF3 O
C CF3 F3C
O
CH3CH2O C
O(CH2)10O
C OCH2CH3
CF3
HO C
CF3
C OH
F3C
C OH
CF3
.
xH2O
HOCH2CH2O
OCH2CH2OH
CF3
B2038
B1525
B2753
O
HOCH2
C OH
B2396
CH2OH
HO
CH3
B1715
HO
OH
CH3CH2 C CH2OH CH2OH
B1568
CH3
CH3
OH
B2664
CH3
CH3
HO
OH
B1180
OH
B1585 COOH
HO
HO
CH3
CH3
C
C
CH3
CH3
OH
O
N C N
O
CH2 OCH2CH2CH
OH
D2179
D2022
D2236
NH2
CH3
NH2
. 2HCl
H2N NH2
N CH3
N
NH2
N N
N NH2
D2227
CH3 CH3
CH3
SH
D1888
D2232
NH2
SH Cl
CHO
D2143
OH
NH2
N N
N NH2
CH3O
N N
NH2
D3872
NH2
H2N
. 2HCl OH NH2
D2225
CH2
Br N
N N
NHCH2
CH2NH
NH2
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
Br
295
Reagents for High-Performance Polymer Research
D1910
D3223
Br
D2151
D1957
Br
CH3
C CH Cl
N HO
C CH2
Cl
C
D1973
C
CH3
CH3
CH2 C
OH
C CH2
CH3 C CH2
C CH
D2202
D3267
D2183
D2208
D2247 O
NH2 CH3 CH3O
CH
OCH3
HO
C
NH2
OH
C OH
CH3
O2N
CH3
OH CH3
CH3
CH2CH(CH3)2
OH C OH
NH2
NO2
O
D0958 CH
E0391 CH
CH2
E0392
E0448
O
CH2
O
HO
C OH
O
O
O CH
E0415
O
OCH2CH2O
CH2
CH
CH2
E0414
OCH2CH2O
C OH
OH
O
O
O
HO C
C OH
E0664
E0432
A1122 NH2
O
O
CH3CH2O C
O(CH2)2O
HO
CH
CH3
OH HO
C OCH2CH3
CH
OH
CH3(CH2)3 CH CH2CH3
C CH
H1166
M1098
CH3
CH3
HO
CH3
M1683
CH3
P0984 CH2OH
CH3
OH HO
CH
N0519
C
OH
OH
OH CH2
OH CH2
OH
O
NO2
CH2
O
HN OH
CH3
CH3
CH3
CH3
CH3
CH3
O
CH2OH
P0170
P0169 P1892
T0010
NH
T0017
O
T1457 NH2
NH2 O H2N
NH2
O
H C
C H
Cl
O
O
C
C Cl
CH3
CH3
NH2
CH3 NH2
C0046
T1079
T1361
V0059 Br
O
CH3
O
O
HO C
Cl
V0054 O
O
C OH
C
O
CH
O N
O
O
Br
V0057
N
296
CH
CH2
X0022 NH2
H2N
Br
CH2NCO
N N
CH
CH2
CH2NCO
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
CH2
Reagents for High-Performance Polymer Research
Product No. Product Name A1019 D0605 B1505 B2076 B1549 B1499 B1336 B2752 B1500 B1403 B1419 F0447 B2038 B1525 B2753 B2396 B1568 B1715 B2664 B1180 B1585 D2179 D2022 D2236 D2225 D2232 D1888 D2227 D2143 D3872 D1910 D3223 D2151 D1957 D1973 D2202 D3267 D2183 D2208 D2247 D0958
4-Aminostyrene (stabilized with HQ) 1,4-Benzenedimethanol 1,4-Benzenedithiol 1,1-Bis(4-aminophenyl)cyclohexane 9,9-Bis(4-aminophenyl)fluorene 1,10-Bis(4-carboxyphenoxy)decane N,N '-Bis(4-chlorophenyl)-N,N '-diphenyl-1,4-phenylenediamine 1,1-Bis(3-cyclohexyl-4-hydroxyphenyl)cyclohexane 1,10-Bis[4-(ethoxycarbonyl)phenoxy]decane 1,3-Bis(hexafluoro-α-hydroxyisopropyl)benzene 1,4-Bis(hexafluoro-α-hydroxyisopropyl)benzene Hydrate 9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluorene 2,2-Bis(hydroxymethyl)butyric Acid 2,6-Bis(hydroxymethyl)-p-cresol 1,1-Bis(4-hydroxy-3-methylphenyl)cyclohexane 9,9-Bis(4-hydroxy-3-methylphenyl)fluorene 1,1-Bis(4-hydroxyphenyl)cyclohexane 9,9-Bis(4-hydroxyphenyl)fluorene 1,3-Bis[2-(4-hydroxyphenyl)-2-propyl]benzene 1,1-Bis(morpholino)ethylene 4-(3-Butenyloxy)benzoic Acid 2-Chloro-5-methyl-1,4-phenylenediamine 2,5-Diamino-1,4-benzenedithiol Dihydrochloride 2,4-Diamino-6-dimethylamino-1,3,5-triazine 2,4-Diamino-6-isopropoxy-1,3,5-triazine 2,4-Diamino-6-methoxy-1,3,5-triazine 4,6-Diaminoresorcinol Dihydrochloride 2,4-Diamino-1,3,5-triazine α,α'-Dianilino-p-xylene 2,2'-Dibromo-9,9'-spirobi[9H-fluorene] 4,4'-Dibromotriphenylamine 1,1-Dichloro-2,2-bis(4-hydroxyphenyl)ethylene 1,4-Diethynylbenzene 1,3-Diisopropenylbenzene (stabilized with TBC) 1,4-Diisopropenylbenzene 4,4'-Dimethoxybenzhydrylamine 4,4'-(1,3-Dimethylbutylidene)diphenol 2,5-Dimethyl-1,4-phenylenediamine 2,5-Dimethylterephthalic Acid 4,6-Dinitroresorcinol (wetted with ca. 20% Water, containing 5g on a dry weight basis) Divinylbenzene (m- and p- mixture) (contains Ethylvinylbenzene, Diethylbenzene)
E0391 E0392 E0448 E0415 E0414 E0664 E0432 A1122 H1166 M1098 M1683 N0519 P0984 P0169 P1892 P0170 T0010 T0017 T1457 C0046 T1079 T1361 V0059 V0054 V0057 X0022
exo-3,6-Epoxy-1,2,3,6-tetrahydrophthalic Acid exo-3,6-Epoxy-1,2,3,6-tetrahydrophthalic Anhydride 3,3'-Ethylenedioxydiphenol Ethylene Glycol Bis(4-carboxyphenyl) Ether Ethylene Glycol Bis[4-(ethoxycarbonyl)phenyl] Ether 4,4'-(2-Ethylhexylidene)diphenol 4,4'-Ethylidenebisphenol 3-Ethynylaniline 4,4'-(2-Hydroxybenzylidene)bis(2,3,6-trimethylphenol) 4,4'-(α-Methylbenzylidene)bisphenol 2,2'-Methylenebis[6-(2-hydroxy-5-methylbenzyl)-p-cresol] 2-Nitro-p-xylylene Glycol 3,4,9,10-Perylenetetracarboxylic Diimide 1,3-Phenylenediamine 1,3-Phenylenediamine 1,4-Phenylenediamine Terephthalaldehyde Terephthaloyl Chloride 2,3,5,6-Tetramethyl-1,4-phenylenediamine Trimellitic Anhydride Trimellitic Anhydride Chloride Tris(4-bromophenyl)amine 4-Vinylbenzoic Acid (stabilized with BHT) 4-Vinylbiphenyl 2-Vinyl-4,6-diamino-1,3,5-triazine m-Xylylene Diisocyanate
Unit Size 5g 25g 1g 5g
5g 5g 5g 25g 25g 25g 25g 25g 25g
5g
5g 1g 1g
1g 25ml 1g
5g 25g 5g 25ml
(stabilized with TBC)
25g 1g
25g
25g
25g 25g 25g 25g 25g 5g 25g 25g 1g
5g 1g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 500g 5g 25g 25g 5g 1g 25g 5g 25g 25g 25g 500g 500g 25g 250g 500g 500g 250g 10g 5g 25g 25g 5g 1g 5g 25g 5g 5g 1g 100mg 5g 5g 500ml 10g 25g 500g 25g 25g 5g 500ml 25g 500g 25g 5g 5g 25g 500g 10g 25g 500g 25g 5g 25g 500g 500g 250g 500g 500g 25g 500g 500g 25g 25g 5g 25g 500g
297
Reagents for High-Performance Polymer Research
References 1) M. Ishikawa, 2) J. Furukawa, 3) N. Kawashima,
298
1990,
, 203; M. Ishikawa, 1992, , 57; J. Furukawa,
1993,
, 564. 1992, 2003,
, 62. , 496.
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Metal-Organic Frameworks (MOFs / PCPs)
Metal-Organic Frameworks (MOFs / PCPs) Porous metal-organic frameworks (MOFs) (other name: porous coordination polymers (PCPs)) have attracted wide scientific attention for the potential application to gas storage, gas separation, catalysis and nanospace engineering.1) MOFs (PCPs) are constructed mainly by coordination bonds between metal cations and multidentate ligands. Their specificities depend on the pore shape, size, and chemical environments of the voids or channels. Kitagawa . have reported the first utilization of a MOF as an electrocatalyst for oxidation of ethanol to aldehyde, for which the potential was comparable with Pt-based catalysts.2) Recently, Kaneko, Kanoh, Kondo, Kajiro . have developed a quite unique Cu complex MOF [Cu(bpy)(BF4)2(H2O)2]bpy (bpy = 4,4’ -bipyridine),3) named as pre-ELM-11 (ELM stands for Elastic LayerStructured MOF). Upon heating and dehydration, pre-ELM-11 converts to an innovative and stable gas absorbent ELM-11 [Cu(bpy)2(BF4)2] (Figure 1). ELM-11 has structural flexibility, and its structural transformation occurs easier than traditional rigid MOFs. And the gate type adsorption isotherm on ELM-11, which has a predominantly rectangular shaped hysteresis, is quite unique (Figure 2).
Figure 1. Structure Transformation between pre-ELM-11 and ELM-11 Pre-ELM-11 is easily converted to ELM-11 by an activation process (dehydration). Recommended conditions are 120℃ for 3 h in vacuo. ELM-11 is stable on drying at rt. ELM-11 rapidly absorbs moisture in atmospheric conditions and changes its structure to pre-ELM-11, but can be re-transformed.
Figure 2. Schematic representation of the gate adsorption of CO23a) Pre-ELM-11 is also utilized as a catalyst in organic synthesis for molecular oxygen-derived oxidation and epoxide alcoholysis (Scheme).4)
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
299
Metal-Organic Frameworks (MOFs / PCPs)
OSi(CH3)3 CH3
4a) O2, pre-ELM-11 (10 mol%)
O CH3
O
Y. 85 %
EtOH - H2O, 0 ºC, 4.5 h
OH CH3 4b)
O2, pre-ELM-11 (10 mol%) (0.5 eq.) LiOH - H2O (0.8 eq.) P(OEt)3
Y. 84 %
EtOH, 80 ºC, 14.5 h
OCH3
O pre-ELM-11 (9 mol%)
CH3OH
4c)
OH
rt, 2 h Y. 94 %
Scheme. Molecular oxygen-derived oxidation and epoxide alcoholysis using pre-ELM-11
C2409
[Cu(bpy)(BF4)2(H2O)2]bpy
MOF / PCP
Product No. Product Name C2409
Unit Size
pre-ELM-11
5g
B0043
B1191
B3622 O O
COOH O HO C
Materials for MOF / PCP
B0469
HOOC
C2410
HO C C OH
O C OH
COOH
D3899
N
I0001
N
I0155
O
O
C OH
N
OH
N
N
Cu(BF4)2
C OH
N H
HO
O
C OH
C OH
O
M1835
M0345
N0377
O N N H
O
300
C OH
O
OH
C OH
OH CH3
N0272 O
O
C OH
CH3O
N0520
HO
NO2
O O
O2N
C OH
O
OH
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Metal-Organic Frameworks (MOFs / PCPs)
P0545
T0166
T2647 O
O N N
O C OH
C OH
C OH C OH C OH
O
O
O HO C
Product No. Product Name B0043 B1191 B3622 B0469 C2410 D3899 I0001 I0155 M1835 M0345 N0377 N0520 N0272 P0545 T0166 T2647
1,3,5-Benzenetricarboxylic Acid 4,4'-Biphenyldicarboxylic Acid 2,2'-Bipyridine-3,3'-dicarboxylic Acid 4,4'-Bipyridyl Copper(II) Tetrafluoroborate (ca. 45% in Water) 2,5-Dihydroxyterephthalic Acid Imidazole Isophthalic Acid 5-Methoxyisophthalic Acid 2-Methylimidazole 2,6-Naphthalenedicarboxylic Acid 5-Nitroisophthalic Acid Nitroterephthalic Acid 2,3-Pyrazinedicarboxylic Acid Terephthalic Acid 1,3,5-Tris(4-carboxyphenyl)benzene
O C OH
Unit Size 25g 5g 1g 25g 5g 25g 25g 25g 25g 25g
25g 1g
500g 25g 5g 500g 500g 25g 500g 500g 5g 500g 250g 500g 25g 25g 500g 5g
References 1) Reviews of metal-organic frameworks (MOFs / PCPs) a)“Chemistry of Coordination Space”, ed. by H. Nishihara, . 2007, , 2489-2766. b) M. P. Suh, Y. E. Cheon, E. Y. Lee, . 2008, , 1007. c) A. Corma, H. García, F. X. L. Xamena, . 2010, , 4606. 2) Electrocatalyst for ethanol oxidation L. Yang, S. Kinoshita, T. Yamada, S. Kanda, H. Kitagawa, M. Tokunaga, T. Ishimoto, T. Ogura, R. Nagumo, A. Miyamoto, M. Koyama, . 2010, , 5348. 3) For gas storage and gas separation research of pre-ELM-11 a) D. Li, K. Kaneko, . 2001, , 50. b) A. Kondo, H. Noguchi, S. Ohnishi, H. Kajiro, A. Tohdoh, Y. Hattori, W.-C. Xu, H. Tanaka, H. Kanoh, K. Kaneko, . 2006, , 2581. 2007, c) H. Noguchi, A. Kondo, Y. Hattori, H. Kajiro, H. Kanoh, K. Kaneko, , 248. d) H. Kanoh, A. Kondo, H. Noguchi, H. Kajiro, A. Tohdoh, Y. Hattori, W.-C. Xu, M. Inoue, T. Sugiura, K. Morita, H. Tanaka, T. Ohba, K. Kaneko, . 2009, , 1. e) H. Kajiro, A. Kondo, K. Kaneko, H. Kanoh, . 2010, , 3803. f) Nippon Steel Corporation, Nippon Steel Chemical Co., Ltd., Institute of Research and Innovation, Jpn. Kokai Tokkyo Koho 2005 162624; Nippon Steel Corporation, Nippon Steel Chemical Co., Ltd., Institute of Research and Innovation, Jpn. Kokai Tokkyo Koho 2005 162625; Nippon Steel Corporation, Institute of Research and Innovation, Jpn. Kokai Tokkyo Koho 2005 336129; Nippon Steel Corporation, Jpn. Kokai Tokkyo Koho 2005 232031. 4) For catalysis research of pre-ELM-11 a) T. Arai, H. Takasugi, T. Sato, H. Noguchi, H. Kanoh, K. Kaneko, A. Yanagisawa, . 2005, , 1590. b) T. Arai, T. Sato, H. Noguchi, H. Kanoh, K. Kaneko, A. Yanagisawa, . 2006, , 1094. c) D. Jiang, T. Mallat, F. Krumeich, A. Baiker, . 2008, , 390.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
301
Photopolymerization Initiators
Photopolymerization Initiators Photopolymerization initiators are used in many fields to generate photocurable composites. These composites are polymerized by irradiation with UV light and electron beam which leads to altered physical properties of the composites such as solubility, viscosity and adhesiveness. In particular, the phenomenon in which a liquid changes into a solid is most useful and is applied to surface-treating techniques in fields including paints, printing inks, dental materials, lithography, photoresist, etc. A growing number of intensive studies have been made for the development of improved properties for novel photopolymerization initiators. Radicals
hν
Photopolymerization Initiators
Cations
Anions
Photopolymerization initiators can be divided roughly into three groups with the generated active species, as shown in the upper figure. The conventional photopolymerization initiators generate free radicals upon light irradiation, and the resulting radical starts the polymerization process. Typical initiators are represented by benzoin derivatives. Photo-acid generators which produce cations (acid) by light irradiation, were put to practical use in the late 1990s. Photo-base generators, which produce anions (base) by light irradiation, are of current interest in research. Photopolymerization initiators are divided roughly into three groups as shown above. For a photopolymerization initiator to be an excellent initiator the following properties must be considered; (1) High quantum yields in the generation of radicals, cations and anions (2) Overlap in absorption wavelength of the photopolymerization initiators and emission wavelength of the light source (3) High thermal stability and high stability in darkness (4) Highly soluble in monomers and oligomers In addition to those just developed, we have a wide assortment of initiators, such as benzoin derivatives which are already in use. A0061
A1028
O CH3O
C C
B0079 B0222
CCl3 O O
O O
C CH3
B3633
B0050 B0221
N
OH O
N
C C
OCH3
CH C Cl3C
O
N O
B1019
B1015
B0942
B0869
B0083
O
O
O
O
O
CH C
CH C
CH C
CH C
C
OCH2CH3
OCH2CH(CH3)2
OCH(CH3)2
OCH3
B0103
B1164
B1267
B2380
B2381
O C COOH
302
O
O
C
C OH
t Bu
CH3
S
t Bu
I
t Bu
I
t Bu
Bz
PF6
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
CF3SO3
Photopolymerization Initiators
B1225
B0481
B0139 B1275
C0014
Cl
C1150 CH3
O
N
N N
Et2N
N
O
C
NEt2
Me2N
CH3 CH3
O
C
Cl O
NMe2
C O
Cl
relative
C0292
C1485 C0136
D1801
D1621
D1640
O O Cl
Cl
S
D2375
O OCH2CH3
O
Cl
C
C
Cl
C CH OCH2CH3
O
D1702
D2963
D2248
D2238
O CCl3
O OCH3
CH2CH3
N
C C S
Cl3C
OCH3
I
OCH3
N CH CH
N
I
OCH3
D2253
D3358
E0063
PF6
AsF6
CH2CH3
F0021
F0362
O
O
P
I
CCl3
CH2CH3
C O
N O
CH3
CH3
CH
CH
N N
CF3SO3
O
O
CCl3
CH3
H0617
H0991
P0211
I0591 CH3
O OH
O OH
C
CH3
O NOH
C C CH3
CH3
O CH
F
F
F 4
CH3 CH3
B
S
M2140
M0792
B1231
M1209
O
N
CCl3
O
N
C
N
Cl3C
I F
F
CCl3 N
CH
C C CH3
CH3
M1245
I0678
N
Cl3C
N
CH CH
OCH3
M2028
CH
CH
N
COOCH3
CH3
N0528
O
N
N
OCH3
CCl3 N CH3
P1410
CCl3
P1377
B0486
O CH3 O O
N C
NO2
C
SCH3
CH3O C
CH3
O CH3
T0157
O
O
SO2
S
CH3
C CH
C OCH3
T1188
S
S
N
CH3
T1608
CH3
O
CH3
O
S CBr3
N C S C N CH3
CH3 CH3
CH3
SO2CBr3
CH3
N H
T2041
T2042 CH3
CH3
CH3
S
N C S S C N
S
S
BF4
S
PF6 CH3
CH3
CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
CH3 CF3SO3
303
Photopolymerization Initiators
Product No. Product Name A0061 A1028 B0050 B0221 B3633 B0079 B0222 B1019 B1015 B0942 B0869 B0083 B0103 B1164 B1267 B2380 B2381 B1225 B0139 B1275 B0481 C0014 C1150 C1485 C0136 C0292 D1801 D1621 D1640 D2375 D1702 D2963 D2248 D2238 D2253 D3358 E0063 F0021 F0362 H0617 H0991 P0211 I0591 I0678 M1245 M2140 M0792 B1231 M1209 M2028 N0528 P1410 P1377 B0486 T0157 T1188 T1608 T2041 T2042
Unit Size
Acetophenone p-Anisil Benzil Benzil Zone Refined (number of passes:22) 2-(1,3-Benzodioxol-5-yl)-4,6-bis(trichloromethyl)-1,3,5-triazine Benzoin Benzoin Zone Refined (number of passes:40) Benzoin Ethyl Ether Benzoin Isobutyl Ether Benzoin Isopropyl Ether Benzoin Methyl Ether Benzophenone 2-Benzoylbenzoic Acid 4-Benzoylbenzoic Acid 4-Benzoyl 4'-Methyldiphenyl Sulfide Bis(4-tert-butylphenyl)iodonium Hexafluorophosphate Bis(4-tert-butylphenyl)iodonium Trifluoromethanesulfonate 2,2'-Bis(2-chlorophenyl)-4,4',5,5'-tetraphenyl-1,2'-biimidazole 4,4'-Bis(diethylamino)benzophenone 4,4'-Bis(diethylamino)benzophenone 4,4'-Bis(dimethylamino)benzophenone (±)-Camphorquinone 2-Chlorobenzophenone 4-Chlorobenzophenone 4-Chlorobenzophenone 2-Chlorothioxanthone Dibenzosuberone 4,4'-Dichlorobenzophenone 2,2-Diethoxyacetophenone 2,4-Diethylthioxanthen-9-one 2,2-Dimethoxy-2-phenylacetophenone 2-(3,4-Dimethoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine Diphenyliodonium Hexafluoroarsenate Diphenyliodonium Hexafluorophosphate Diphenyliodonium Trifluoromethanesulfonate Diphenyl(2,4,6-trimethylbenzoyl)phosphine Oxide 2-Ethylanthraquinone 9-Fluorenone 2-[2-(Furan-2-yl)vinyl]-4,6-bis(trichloromethyl)-1,3,5-triazine 1-Hydroxycyclohexyl Phenyl Ketone 2-Hydroxy-2-methylpropiophenone 2-Isonitrosopropiophenone 4-Isopropyl-4'-methyldiphenyliodonium Tetrakis(pentafluorophenyl)borate 2-Isopropylthioxanthone 2-(4-Methoxyphenyl)-4,6-bis(trichloromethyl)-1,3,5-triazine 2-(4-Methoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine N-Methyl-9-acridone Methyl 2-Benzoylbenzoate 2-[2-(5-Methylfuran-2-yl)vinyl]-4,6-bis(trichloromethyl)-1,3,5-triazine 2-Methyl-4'-(methylthio)-2-morpholinopropiophenone Nifedipine 2-Phenyl-2-(p-toluenesulfonyloxy)acetophenone 2-Pyridyl Tribromomethyl Sulfone Tetramethylthiuram Disulfide Tetramethylthiuram Monosulfide Tribromomethyl Phenyl Sulfone Triphenylsulfonium Tetrafluoroborate Tri-p-tolylsulfonium Hexafluorophosphate Tri-p-tolylsulfonium Trifluoromethanesulfonate
25g
1g
500g 25g 25g 500g 1sample 5g 25g 500g 1sample 25g 500g 25g 500g 25g 500g 25g 500g 25g 500g 25g 500g 5g 25g 10g 1g 5g 1g 5g 25g 25g 500g 25g 500g 25g 500g 5g 25g 25g 500g 25g 500g 25g 5g 25g 25g 500g 25g 500g 25g 500g 25g 250g 25g 500g 5g 1g 5g 25g 1g 5g 25g 25g 500g 25g 500g 5g 25g 500g 25g 500g 25g 5g 25g 25g 5g 25g 5g 5g 25g 25g 500g 5g 25g 500g 10g 25g 1g 5g 25g 25g 500g 25g 500g 25g 1g 5g 1g 1g 5g
References 1) M. Kakuoka, 2) M. Kakuoka, 3) T. Yamaoka,
304
2001, 497. 1999, 592. 1989, , 144.
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Silane Coupling Agents
Silane Coupling Agents Silane coupling agents are organosilicone compounds having two functional groups with different reactivity. One of the two functional groups reacts with organic materials and the other reacts with inorganic materials. Their general structure is as follows: Y R Si
X
3
Where Y denotes a functional group that links with organic materials, e.g. vinyl, epoxy, amino group and so on. X is a functional group that undergoes hydrolysis by water or moisture to form silanol. This silanol links with inorganic materials. Representative examples of X include chlorine, alkoxy, and acetoxy group. Silane coupling agents are effective for the improved adhesion at the interface between the organic and inorganic materials and have been frequently utilized to enhance the strength and improve the performance of glass-fiber reinforced plastics. Recently, they have been used in the manufacture of inorganic-organic hybrid materials such as the laminating board for printed circuit boards, artificial marble, plastic magnets, and silica-immobilized bioactive compounds. In addition to the original purpose of improving the adhesiveness of an interface, different applications are being explored. Examples include synthesis of moisture crosslinkable polymers using the reactivity of hydrolytic functional group, to give antistatic and antibacterial properties from surface treatment using silane coupling agents. It is expected that silane coupling agents will be applied in many fields.
A1538
A0785
OCH2CH3
Cl CH2 CHCH2
Vinyl Group
D2318
D3386
CH
Si CH3
Cl
CH2 CHCH2
T0407
OCH3 CH2 CH
OCH2CH3
Si
CH3
OCH3
Si OCH2CH3
V0044
Si OCH3 OCH3
V0042
OCH2CH3 CH2 CH SiCl3
OCH3 CH2 CHCH2
OCH2CH3
Cl
OCH2CH3 CH2
Si
A1504
CH2 CH Si OCH2CH3 OCH2CH3
OCH3 CH2 CH Si
OCH3
OCH3
V0048
OCH2CH2OCH3 CH2 CH Si OCH2CH2OCH3 OCH2CH2OCH3
Product No. Product Name A1538 A0785 A1504 D2318 D3386 T0407
Allyltrichlorosilane Allyltriethoxysilane Allyltrimethoxysilane Diethoxymethylvinylsilane Dimethoxymethylvinylsilane Trichlorovinylsilane
Unit Size 5g 5ml 25g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 10ml 25ml 25ml 250g 500g
305
Silane Coupling Agents
Product No. Product Name
Unit Size
V0044 V0042 V0048
25ml 25ml 25ml
Triethoxyvinylsilane Vinyltrimethoxysilane Vinyltris(2-methoxyethoxy)silane
D2632
G0261
G0210
OCH2CH3 CH2O(CH2)3 Si
Epoxy Group
O
OCH3
CH3
OCH2CH3
CH2O(CH2)3
OCH3
O
OCH3
Si CH3
CH2O(CH2)3
A1923
A0774
OCH3 H2NCH2CH2NH(CH2)3 Si
Amino Group
OCH2CH3 CH3
T1255
OCH2CH3
OCH2CH3
OCH3
OCH3
OCH3
H2NCH2CH2CH2 Si OCH3
NH(CH2)3
Si OCH3 OCH3
OCH3
OCH2CH3
Product No. Product Name
Unit Size
A0876 A1923 A0774 D1980 A0439 T1255 P1458
25ml
3-(2-Aminoethylamino)propyldimethoxymethylsilane 3-(2-Aminoethylamino)propyltriethoxysilane 3-(2-Aminoethylamino)propyltrimethoxysilane 3-Aminopropyldiethoxymethylsilane 3-Aminopropyltriethoxysilane 3-Aminopropyltrimethoxysilane Trimethoxy[3-(phenylamino)propyl]silane
C1402
Others
ClCH2 Si
OCH2CH3
OCH2CH3
500ml 25g 500g 500ml 500g 500ml 250g
25g 25ml 25g 25ml 25g
C1168
OCH2CH3
306
H2NCH2CH2NH(CH2)3 Si OCH3
P1458
OCH2CH3 H2N(CH2)3 Si OCH2CH3
OCH3
OCH2CH3
CH3 H2NCH2CH2NH(CH2)3 Si OCH2CH3
OCH3
A0439
25ml 500g 500g
25g 25g
A0876
H2N(CH2)3 Si
OCH3
Unit Size
Diethoxy(3-glycidyloxypropyl)methylsilane 3-Glycidyloxypropyl(dimethoxy)methylsilane 3-Glycidyloxypropyltrimethoxysilane
D1980
Si
OCH3
O
Product No. Product Name D2632 G0261 G0210
500ml 500ml 500ml
C0844
OCH3 Cl(CH2)3 Si CH3
Cl Cl(CH2)3 Si Cl
OCH3
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Cl
Silane Coupling Agents
T1253
E0327
OCH2CH3 Cl(CH2)3 Si
OCH2CH3
M1323
O
OCH3 CH2CH2
OCH2CH3
T2705
Si OCH3
O
Si OCH3 OCH3
U0048
O H2N C NH(CH2)3
OCH3
OCH2CH3
O
OCH3 OCH3
OCH2CH3
T2720
O
OCH3
OCH3
H2N C NH(CH2)3
Si
OCH3
CH3
CF3(CF2)5CH2CH2 Si OCH2CH3
OCH2CH3
T1915
CH2 C C O(CH2)3 Si
OCH2CH3
OCH2CH3
CH2 C C O(CH2)3 Si CH3
OCH2CH3
OCH3 ClCH2CH2CH2 Si OCH3
OCH3
T1770
O
OCH2CH3
M0725
OCH3
CH2 CH C O(CH2)3
OCH2CH3 OCN(CH2)3 Si
HS(CH2)3 Si OCH3
OCH2CH3
T2676
Cl
C0840
OCH3
HS(CH2)3 Si OCH2CH3
OCH3
Cl CF3(CF2)5CH2CH2 Si Cl
Cl
A1597
Si (CH2)3SH
I0556
Cl
M0928
OCH2CH3
OCH3 CH3
OCH3
T2577
CF3(CF2)7CH2CH2 Si Cl
M1505
OCH3
CF3CH2CH2 Si OCH3
OCH3
OCH3
V0050
OCH2CH3 Si
OCH2CH3
CH
CH2 H N
OCH2CH3
. HCl N H
Si(OCH3)3
Product No. Product Name C1402 C1168 C0844 T1253 E0327 M1323 M1505 M0928 T2705 T2577 I0556 T2676 T1770 A1597 C0840 M0725 T1915 T2720 U0048 V0050
Unit Size
(Chloromethyl)triethoxysilane 3-Chloropropyldimethoxymethylsilane 3-Chloropropyltrichlorosilane 3-Chloropropyltriethoxysilane 2-(3,4-Epoxycyclohexyl)ethyltrimethoxysilane 3-Mercaptopropyl(dimethoxy)methylsilane (3-Mercaptopropyl)triethoxysilane (3-Mercaptopropyl)trimethoxysilane Trichloro(1H,1H,2H,2H-heptadecafluorodecyl)silane Trichloro(1H,1H,2H,2H-tridecafluoro-n-octyl)silane 3-(Triethoxysilyl)propyl Isocyanate 3-(Triethoxysilyl)propyl Methacrylate Triethoxy-1H,1H,2H,2H-tridecafluoro-n-octylsilane 3-(Trimethoxysilyl)propyl Acrylate (stabilized with MEHQ) 3-Trimethoxysilylpropyl Chloride 3-(Trimethoxysilyl)propyl Methacrylate (stabilized with BHT) 1-[3-(Trimethoxysilyl)propyl]urea Trimethoxy(3,3,3-trifluoropropyl)silane 3-Ureidopropyltriethoxysilane (40-50% in Methanol) N-[2-(N-Vinylbenzylamino)ethyl]-3-aminopropyltrimethoxysilane Hydrochloride
5g 25ml 25ml 25g 25ml 5g 25g 5g 25ml 25ml 25g 5g 25ml
25ml
(30-40% in Methanol)
B0393
C1259
Cl
Intermediates
10g 25g 25g 500ml 500ml 25ml 500g 100ml 25g 5g 100g 25g 25g 25g 500ml 500ml 250g 25g 500ml
CH3(CH2)3 Si Cl Cl
C0892
OCH2CH3 NCCH2CH2 Si
SiCl3
OCH2CH3
OCH2CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
307
Silane Coupling Agents
D1486
D1553
D0454
CH3
O
Cl CH3(CH2)9 Si Cl
CH3
O
C O Si O C CH3
D2319
CH3(CH2)11 Si Cl
OCH3
CH3(CH2)11 Si OCH2CH3
O0165
O0256
O0168
OCH3
OCH2CH3 CH3(CH2)17 Si OCH2CH3
CH3(CH2)17 Si OCH3
P0240
T1786
OCH3
Cl Cl
CH3(CH2)5 Si
P0736
OCH2CH3
Cl
CH3(CH2)7 Si OCH2CH3
OCH2CH3 CH3(CH2)4 Si OCH2CH3
OCH2CH3
Cl
T1322
OCH3
OCH3
Cl
O0171
CH3(CH2)7 Si Cl
OCH3
OCH2CH3
H0879
CH3CH2 Si
OCH2CH3
Cl
OCH3
E0188
OCH2CH3
Cl
Si CH3
Si
CH3
D1510
OCH3
OCH3
CH3O Si OCH3
CH3
D1509
D1731
CH3
CH3 CH3CH2O Si OCH2CH3
CH3
Cl
D1052
H0547
OCH2CH3
M0450
O
SiCl3
O
O C CH3
CH3 C O Si
CH3
O C CH3
Si
Cl
Cl
Cl NCCH2CH2
Cl
CH3(CH2)5 Si Cl
CH3
Cl
Cl
Si Cl Cl
O
O0079
P0371
T0924
Cl
CH3(CH2)2 Si Cl
Cl
P0857
OCH3
Si
Si
OCH3
OCH3
OCH3
Product No. Product Name
308
CH3CH2
Si OCH2CH3 OCH2CH3
OCH2CH3 CH3
Si OCH2CH3 OCH2CH3
T1801
OCH3 OCH3
B0393 C1259 C0892 D1486 D1553 D0454 D1052 D1731 D2319 D1509 D1510 E0188 H0879 O0165
Cl
Cl
M0660
CH3
CH3(CH2)13 Si Cl
M0451
OCH2CH3
Cl
Cl
CH3(CH2)17 Si Cl
E0189
Butyltrichlorosilane 2-Cyanoethyltriethoxysilane Cyclohexyltrichlorosilane Decyltrichlorosilane Diacetoxydimethylsilane Diethoxydimethylsilane Dimethoxydimethylsilane Dimethoxydiphenylsilane Dimethoxymethylphenylsilane Dodecyltrichlorosilane Dodecyltriethoxysilane Ethyltrichlorosilane Hexyltrimethoxysilane Octadecyltriethoxysilane
OCH3 CH3(CH2)2 Si OCH3 OCH3
Unit Size 25ml 5g
25ml 25g 25ml 25ml 10ml 25g 25ml
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
25g 250ml 25g 25ml 10g 500ml 500g 500ml 100ml 25ml 10ml 500g 500ml 25g
Silane Coupling Agents
Product No. Product Name O0256 O0168 O0171 P0736 P0240 T1786 T1322 H0547 M0450 O0079 P0371 T0924 E0189 M0451 M0660 P0857 T1801
Octadecyltrimethoxysilane n-Octyltrichlorosilane n-Octyltriethoxysilane Pentyltriethoxysilane Phenyltrichlorosilane Triacetoxymethylsilane Trichloro-2-cyanoethylsilane Trichlorohexylsilane Trichloro(methyl)silane Trichlorooctadecylsilane Trichloro(propyl)silane Trichlorotetradecylsilane Triethoxyethylsilane Triethoxymethylsilane Trimethoxy(methyl)silane Trimethoxyphenylsilane Trimethoxy(propyl)silane
Unit Size 25g 25ml 5ml 25g
25g 25g
25ml 25ml 25ml 25ml
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25ml 250g 500ml 25ml 500g 25g 25g 25ml 500g 500g 25g 10ml 25ml 500ml 500ml 500ml 500ml
309
Pressure & Heat Sensitive Recording Materials
Pressure & Heat Sensitive Recording Materials Fluoran compounds, which are a type of colorless dye (color former), develop color via a ring-opening reaction when interacted with acids (developer), as shown in the following scheme. Because this reaction is reversible, decoloration occurs in a reversible manner under basic conditions. CH3 CH3
CH3
CH3
N
N
O
CH3
CH3
CH3
N
N
O
CH3
HX O
COOH
X
Base
O
CH3 N CH3
CH3
N
CH3
[Violet]
[Non Color]
Pressure and heat sensitive recording systems utilize this color developing mechanism in which color formers, developers and sensitizers are intimately incorporated. In pressure sensitive recording, the coloration occurs as follows: Capsules containing color former are destroyed by pressure and the color former makes contact with the developer coated support material. In heat sensitive recording, both color former and developer, which are dispersed on the support material, are thermally melted, thus contacting each other to initiate the coloring reaction. Furthermore, a low melting point sensitizer is also added to achieve a high sensitivity. Recently, the technique has been applied to re-writable recording paper, which can be used for repeated writing and erasing. This technique has been applied to print on commuter passes or prepaid cards. By combining acid-generating methods with the coloring mechanism, new applications can be expected for these materials. Capsule containing color former and oil
Pressure Thermal head Support
Binding resin
Heat
Heat sensing layer Base paper Developer coated layer Developed color
Color former (colorless dye) Developer (solid acid including bisphenol A) Colored dye
B0207
B2628 O
CH3CH2
C
CH3CH2
N
C1946 O
N
CH2CH3 CH2CH3
CH3(CH2)3 CH3(CH2)3
O
N
N
Color Formers
CH3
C0741
D3204
CH3 CH3
NH
N
S
N
D3203
CH3 O
CH3
NO2
D3202
Cl O
D3205
CH3
N
N
O C O
CH3
CH3CH2 CH3CH2 CH3CH2 N
CH3CH2
O
N
CH3CH2
O
CH3CH2
CH3
N
N
O
CH3
CH3O
O
OCH3
CH2 N
O
CH2
O
O
O
310
O
N
CH3
O
O CH3 O
CH3
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
O
Pressure & Heat Sensitive Recording Materials
D3201 CH3CH2 CH3CH2
CH3 CH3
N
C
N
O
CH3
O
Product No. Product Name B0207 B2628 C1946 C0741 D3204 D3203 D3202 D3205 D3201
Unit Size
Benzoyl Leuco Methylene Blue 3',6'-Bis(diethylamino)-2-(4-nitrophenyl)spiro[isoindole-1,9'-xanthene]-3-one 2'-(2-Chloroanilino)-6'-(dibutylamino)fluoran Crystal Violet Lactone 2'-(Dibenzylamino)-6'-(diethylamino)fluoran 6'-(Diethylamino)-1',2'-benzofluoran 6'-(Diethylamino)-1',3'-dimethylfluoran 3',6'-Dimethoxyfluoran 3-(1,2-Dimethyl-3-indolyl)-3-[4-(diethylamino)-2-methylphenyl]phthalide
H0209
1g
25g 25g 500g 25g 25g 25g 25g 25g 25g
25g
B0813
B0464
O OH
C OCH2
HO
Developers
OH
HO OH
B2748
B2752 CH3 CH3CH2
HC
CH CH3
HO
C
CH3
B2749
HO
B2750
OH
CH2CH3 HO
CH3
B2753
HC
CH CH3
HO
C
CH3
C
B1567
B1568
CH3
HO
B1715
HO
OH
CH3
OH
CH3
CH3
CH3 CH3
OH HO
C
CH3
B2751
CH3
CH3
OH
OH
CH3 CH3
CH3
HO
OH
C
OH
CH3
CH3
HO
B1563
B0494
HO
D1356
CH3
CH3
C
C
CH3
CH3
B2664
CH3 OH
HO
C
HO
OH
CH3
B0495
OH
B0735
D2121
CH3
CH3
C
C
CH3
CH3
OH
B0819
OH O HO
S
OH HO
S
HO
OH
O
OH HO
CH2
OH
O
CH3 C CH3 CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
311
Pressure & Heat Sensitive Recording Materials
D3267
E0664
E0432
H1166 CH3
CH3 HO
OH HO
C
OH HO
HO
CH
CH3
N0026
CH3
OH OH
CH3
H0216
CH3
CH3
CH
OH
CH3(CH2)3 CH CH2CH3
CH2CH(CH3)2
M1410
CH
CH3
M1684
CH3
N0027
HO
CH3 CH2
OH
P0201
O C OCH3
OH
OH
OH OH
CH2 OH
OH
R0008
T0032
T0144
T2259
T1254 CH3
Br
OH
Br CH3
CH3 HO
OH
C Br
CH3 C CH2 C CH3
CH3
OH
HO
CH3 CH3
HO
OH
C
OH
CH2
OH
Br OH
T1428 OH
HO
CH3 C
C CH3
CH3
OH
Product No. Product Name H0209 B0813 B0464 B2748 B2752 B2749 B2750 B2751 B2753 B1567 B1568 B1715 B1563 B0494 B2664 D1356 B0495 B0735 D2121 B0819 D3267 E0664 E0432 H1166 M1684 M1410 H0216 N0026 N0027 P0201 R0008 T0032
312
Benzyl 4-Hydroxybenzoate 2,2'-Biphenol 4,4'-Biphenol 2,2-Bis(3-sec-butyl-4-hydroxyphenyl)propane 1,1-Bis(3-cyclohexyl-4-hydroxyphenyl)cyclohexane 2,2-Bis(3-cyclohexyl-4-hydroxyphenyl)propane 2,2-Bis(2-hydroxy-5-biphenylyl)propane 2,2-Bis(4-hydroxy-3-isopropylphenyl)propane 1,1-Bis(4-hydroxy-3-methylphenyl)cyclohexane 2,2-Bis(4-hydroxy-3-methylphenyl)propane 1,1-Bis(4-hydroxyphenyl)cyclohexane 9,9-Bis(4-hydroxyphenyl)fluorene α,α'-Bis(4-hydroxyphenyl)-1,4-diisopropylbenzene 2,2-Bis(4-hydroxyphenyl)propane 1,3-Bis[2-(4-hydroxyphenyl)-2-propyl]benzene Bis(4-hydroxyphenyl) Sulfide Bis(4-hydroxyphenyl) Sulfone 4-tert-Butylphenol Zone Refined (number of passes:19) 4,4'-Dihydroxydiphenyl Ether 4,4'-Dihydroxydiphenylmethane 4,4'-(1,3-Dimethylbutylidene)diphenol 4,4'-(2-Ethylhexylidene)diphenol 4,4'-Ethylidenebisphenol 4,4'-(2-Hydroxybenzylidene)bis(2,3,6-trimethylphenol) 4,4'-Methylenebis(2-methylphenol) 1,1'-Methylenedi-2-naphthol Methyl 4-Hydroxybenzoate 1-Naphthol 2-Naphthol 4-Phenylphenol Resorcinol Tetrabromobisphenol A
Unit Size 25g 25g 25g
500g 500g 500g 25g 25g 25g 5g 25g 25g 25g 500g 25g 500g 25g 500g 25g 500g 25g 500g 25g 250g 25g 500g 25g 500g 1sample 25g 500g 5g 25g 25g 500g 25g 25g 500g 25g 25g 25g 25g 500g 25g 500g 25g 250g 25g 500g 25g 500g 25g 500g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
OH
Pressure & Heat Sensitive Recording Materials
Product No. Product Name T0144 T2259 T1254 T1428
Unit Size
4-(1,1,3,3-Tetramethylbutyl)phenol 2,3,4-Trihydroxydiphenylmethane 1,1,1-Tris(4-hydroxyphenyl)ethane α,α,α'-Tris(4-hydroxyphenyl)-1-ethyl-4-isopropylbenzene
25g 25g
B1248
B1519
B1619
O
D0159
D0001
D1598
T0015
D2017 O
OCH2 CH
O CH2 S CH2
CH3 CH3
CH3 O
O
P0231
O
OCH3
D0866
F0016
O
O
S
C CH2 C
O C O
O
CH
O
D0910
OCH3
CH3
OCH2
C0043
OCH2
CH2
CH3(CH2)20 C OH
Sensitizers
500g 5g 500g 25g
OCH2CH2O
O
F0017
H0067
C0024
L0011
H0283 O O
O
O CH3(CH2)14 C NH2
OCH3 CH3(CH2)4
NH2
CH3(CH2)10
OH OH
M0476
O0238
O0107
O CH3(CH2)12
S0075
CH3(CH2)6
NH2
S0314
(CH2)7 C NH2
OH
O
O C O
CH3(CH2)14 C OH
T0018
NH2
CH3(CH2)16 C NH
Product No. Product Name B1248 B1519 B1619 D0159 D0001 D1598
CH3(CH2)7
H0797
O
O CH3(CH2)16
O
O OH
P0002
Behenic Acid 4-Benzylbiphenyl Benzyl 2-Naphthyl Ether 1,4-Dibenzyloxybenzene Dibenzyl Sulfoxide 2,6-Diisopropylnaphthalene
Unit Size 5g 5g 25g 5g 25g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 25g 500g 25g 250g 500g
313
Pressure & Heat Sensitive Recording Materials
Product No. Product Name T0015 D2017 C0043 D0910 P0231 D0866 F0016 F0017 H0067 C0024 L0011 H0283 M0476 O0238 O0107 P0002 H0797 S0075 S0314 T0018
314
Dimethyl Terephthalate 1,4-Diphenoxybenzene Diphenyl Carbonate 1,3-Diphenyl-1,3-propanedione Diphenyl Sulfone Ethylene Glycol Diphenyl Ether Fluoranthene Fluorene Hexadecanamide Hexanamide Lauric Acid Methyl 3-Hydroxy-2-naphthoate Myristic Acid n-Octanamide Oleamide Palmitic Acid Phenyl 1-Hydroxy-2-naphthoate Stearamide Stearanilide m-Terphenyl
Unit Size 25g 5g 25g 25g 25g 25g 25g 10g 25g 25g 25g 10g 25g 25g 25g 25g 25g 25g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
500g 25g 500g 500g 500g 5g 500g 500g 25g 25g 500g 500g 500g 25g 500g 500g 500g 500g 500g 500g
Ethylene Glycols & Monofunctional Ethylene Glycols
Ethylene Glycols & Monofunctional Ethylene Glycols Ethylene Glycols Product No. Product Name
Unit Size
E0105 D0495 T0428 T0099 P1154 H0934 H1045 O0295 N0698 D2900 D2901
25g 100g 25g 25g 5g
Ethylene Glycol Diethylene Glycol Triethylene Glycol Tetraethylene Glycol Pentaethylene Glycol Hexaethylene Glycol Heptaethylene Glycol Octaethylene Glycol Nonaethylene Glycol Decaethylene Glycol Dodecaethylene Glycol
500g 500g 500g 500g 25g 5g 1g 1g 1g 1g 1g
Monofunctional Ethylene Glycols Product No. Product Name M0111 E0047 E0514 E0110 B0698 E0301 E0354 H0343 E0264 E0518 E0326 A0301 D1756 D0298 A1059 A0743 P0115 E0504 C0169 C0251 E0302 E0303 B0426 H1048
Ethylene Glycol Monomethyl Ether (=2-Methoxyethanol) Ethylene Glycol Monoethyl Ether (=2-Ethoxyethanol) Ethylene Glycol Monopropyl Ether Ethylene Glycol Monoisopropyl Ether Ethylene Glycol Monobutyl Ether Ethylene Glycol Monoisobutyl Ether Ethylene Glycol Mono-tert-butyl Ether Ethylene Glycol Monohexyl Ether Ethylene Glycol Monododecyl Ether Ethylene Glycol Monovinyl Ether (stabilized with KOH) Ethylene Glycol Monoallyl Ether Ethylene Glycol Mono(2-aminoethyl) Ether [=2-(2-Aminoethoxy)ethanol] Ethylene Glycol Mono[2-(dimethylamino)ethyl] Ether [=2-[2-(Dimethylamino)ethoxy]ethanol] Ethylene Glycol Mono[2-(diethylamino)ethyl] Ether [=2-[2-(Diethylamino)ethoxy]ethanol] Ethylene Glycol Monoacetate (=2-Hydroxyethyl Acetate) Ethylene Glycol Monoacrylate (=2-Hydroxyethyl Acrylate) (stabilized with MEHQ) Ethylene Glycol Monophenyl Ether (=2-Phenoxyethanol) Ethylene Glycol Mono(4-bromophenyl) Ether Ethylene Glycol Mono-2-chloroethyl Ether Ethylene Glycol Mono(4-chlorophenyl) Ether Ethylene Glycol Mono-m-tolyl Ether Ethylene Glycol Mono-p-tolyl Ether Ethylene Glycol Monobenzyl Ether [=2-(Benzyloxy)ethanol] Ethylene Glycol Mono-4-(hydroxymethyl)-2-nitrophenyl Ether
E0113 M0537 E0048 B0699 D0501 D1233 D2623 D3408 T0709 E0167 T1373 T0915 T0768 C1416 T1996 T1372 T0769 T1796
Ethylene Glycol Monosalicylate Diethylene Glycol Monomethyl Ether Diethylene Glycol Monoethyl Ether Diethylene Glycol Monobutyl Ether Diethylene Glycol Monohexyl Ether Diethylene Glycol Monododecyl Ether Diethylene Glycol Monovinyl Ether (stabilized with KOH) Diethylene Glycol Monobenzyl Ether Triethylene Glycol Monomethyl Ether Triethylene Glycol Monoethyl Ether Triethylene Glycol Monoisopropyl Ether Triethylene Glycol Monobutyl Ether Triethylene Glycol Monododecyl Ether Triethylene Glycol Monochlorohydrin [=2-[2-(2-Chloroethoxy)ethoxy]ethanol] Triethylene Glycol Monobenzyl Ether Tetraethylene Glycol Monomethyl Ether Tetraethylene Glycol Monododecyl Ether Tetramethylene Glycol Monovinyl Ether (stabilized with KOH)
[=2-[4-(Hydroxymethyl)-2-nitrophenoxy]ethanol]
Unit Size 25ml 25ml 25ml 25ml 25ml 25ml 25ml 25ml 25ml 25ml 25ml 25ml 25g 25ml 25ml 25g 25ml 5ml 5g 25ml 100mg 25g 25ml 25g 25ml 25ml 25ml 25g 25ml 25ml 5g 25ml 25g 5g 5g 25ml
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500ml 500ml 500ml 500ml 500ml 500ml 500ml 500ml 5ml 500ml 500ml 500ml 500ml 500g 500ml 500ml 500g 25g 500ml 25g 25ml 25g 250ml 1g 500g 500ml 500g 500ml 500ml 5ml 500ml 500g 500ml 500ml 25g 500ml 5ml 100g 25g 25g 5ml 500ml
315
Ethylene Glycols & Monofunctional Ethylene Glycols
Product No. Product Name T1997 P1159 P0372 P1435 H0808 H0444 H1043 H1046 H0445 O0296 O0139 N0699 D2903 D2904 P0671 P1777 P0841 P1776 P0711 P0713 P0714 P0715 P0716 P0872 P0717 P0718 P0719 P0720 P0721 P0722 P0723 P0873 P1775 P0704 P0705 P0706 P0707 P0708 P0709 P0710
316
Tetraethylene Glycol Monobenzyl Ether Pentaethylene Glycol Monomethyl Ether Pentaethylene Glycol Monododecyl Ether Pentaethylene Glycol Monobenzyl Ether Hexaethylene Glycol Monomethyl Ether Hexaethylene Glycol Monododecyl Ether Hexaethylene Glycol Monobenzyl Ether Heptaethylene Glycol Monomethyl Ether Heptaethylene Glycol Monododecyl Ether Octaethylene Glycol Monomethyl Ether Octaethylene Glycol Monododecyl Ether Nonaethylene Glycol Monomethyl Ether Decaethylene Glycol Monomethyl Ether Dodecaethylene Glycol Monomethyl Ether Polyethylene Glycol Monododecyl Ether n≒25 Polyethylene Glycol Monododecyl Ether n≒25 [for Biochemical Research] Polyethylene Glycol Monocetyl Ether n≒23 Polyethylene Glycol Monocetyl Ether n≒23 [for Biochemical Research] Polyethylene Glycol Monooleyl Ether n≒2 Polyethylene Glycol Monooleyl Ether n≒7 Polyethylene Glycol Monooleyl Ether n≒10 Polyethylene Glycol Monooleyl Ether n≒20 Polyethylene Glycol Monooleyl Ether n≒50 Polyethylene Glycol Monolaurate n≒10 Polyethylene Glycol Monostearate n≒2 (palmitate and stearate mixture) Polyethylene Glycol Monostearate n≒4 (palmitate and stearate mixture) Polyethylene Glycol Monostearate n≒10 (palmitate and stearate mixture) Polyethylene Glycol Monostearate n≒25 (palmitate and stearate mixture) Polyethylene Glycol Monostearate n≒40 (palmitate and stearate mixture) Polyethylene Glycol Monostearate n≒45 (palmitate and stearate mixture) Polyethylene Glycol Monostearate n≒55 (palmitate and stearate mixture) Polyethylene Glycol Mono-4-octylphenyl Ether n≒10 Polyethylene Glycol Mono-4-octylphenyl Ether n≒10 [for Biochemical Research] Polyethylene Glycol Mono-4-nonylphenyl Ether n≒2 Polyethylene Glycol Mono-4-nonylphenyl Ether n≒5 Polyethylene Glycol Mono-4-nonylphenyl Ether n≒7.5 Polyethylene Glycol Mono-4-nonylphenyl Ether n≒10 Polyethylene Glycol Mono-4-nonylphenyl Ether n≒15 Polyethylene Glycol Mono-4-nonylphenyl Ether n≒18 Polyethylene Glycol Mono-4-nonylphenyl Ether n≒20
Unit Size 1g
1g
1g 5g
1g 1g 500mg
25g 5g 25g 5g 25g 25g 25g 25g 25g 25g 25g 25g 25g 25g 25g 25g 25g 25g 5g 25g 25g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
5g 5g 5g 5g 25g 5ml 1g 5g 5g 5g 5g 1g 100mg 100mg 500g 25g 500g 25g 500g 500g 500g 500g 500g 500g 500g 500g 500g 500g 500g 500g 500g 500g 25g 25g 500g 25g 500g 25g 25g 25g
Monoprotected Diaminoalkanes
Monoprotected Diaminoalkanes -Boc-diaminoalkanes CH3 CH3
O
C O C NH(CH2)nNH2 CH3
Product No. Product Name N-(tert-Butoxycarbonyl)-1,2-diaminoethane N-(tert-Butoxycarbonyl)-1,3-diaminopropane N-(tert-Butoxycarbonyl)-1,4-diaminobutane N-(tert-Butoxycarbonyl)-1,5-diaminopentane N-(tert-Butoxycarbonyl)-1,6-diaminohexane N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine
A1371 A1372 A1373 A1374 A1375 B3052
Unit Size 1g 1g
5g 1g 5g 1g 1g
25g 5g 25g 5g 5g 5g
-Cbz-diaminoalkanes O CH2O C NH(CH2)nNH2
Product No. Product Name N-Carbobenzoxy-1,2-diaminoethane Hydrochloride N-Carbobenzoxy-1,3-diaminopropane Hydrochloride N-Carbobenzoxy-1,4-diaminobutane Hydrochloride N-Carbobenzoxy-1,5-diaminopentane Hydrochloride N-Carbobenzoxy-1,6-diaminohexane Hydrochloride
C1511 C1512 C1519 C1520 C1521
Unit Size 1g
5g 1g 1g 1g 1g
25g 5g 5g 5g 5g
-( -Ns)-diaminoalkanes NO2 O S NH(CH2)nNH2 O
Product No. Product Name A2329 A1628 A1630 A1661 A1662
N-(2-Aminoethyl)-2-nitrobenzenesulfonamide Hydrochloride N-(3-Aminopropyl)-2-nitrobenzenesulfonamide N-(4-Aminobutyl)-2-nitrobenzenesulfonamide N-(5-Aminopentyl)-2-nitrobenzenesulfonamide Hydrochloride N-(6-Aminohexyl)-2-nitrobenzenesulfonamide Hydrochloride
Unit Size 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 1g 1g 1g 1g
317
3-Aminopyrrolidines
3-Aminopyrrolidines
A1108
A1113
A1112
O NH C CH3 N H
A1104
A1055
B1355
. 2HCl N H
N H
B1559
B1357
B1560
N CH2
M1096
N
CH2
CH2
NHCH2
CH3
N H
D1965
CH2CH3
CH3
N CH2CH3
N CH3
NHCH3 N
M1106
N H
CH3
T1247 O
NHCH3 N H
NH N H
C CF3
. HCl
Product No. Product Name
318
CH3
C O C CH3 CH3
D1859
N H
NHCH2CH3
A1108 A1113 A1112 A1104 A1055 B1355 B1354 B1357 B1559 B1560 B1558 B1356 B1358 M1096
NH N H
CH2
N CH2
E0431
O
NH C CF3 N
D1857
CH3
B1358 O
NHCH3
N C O C CH3
CH2
B1356
N
D1964
N
CH2
NHCH2CH3
N CH3
CH3
NH C O C CH3 CH3
N
N
B1558
O
NH2
NH C CH3
CH2
CH3
O N H
B1354
NH2
NH2
N H
N C CH3
N H
O
O
CH3
N C CH3 O
Racemic
CH3
CH2CH3
3-Acetamidopyrrolidine 3-(N-Acetyl-N-ethylamino)pyrrolidine 3-(N-Acetyl-N-methylamino)pyrrolidine 3-Aminopyrrolidine 3-Aminopyrrolidine Dihydrochloride 1-Benzyl-3-acetamidopyrrolidine 1-Benzyl-3-aminopyrrolidine 1-Benzyl-3-(tert-butoxycarbonylamino)pyrrolidine 1-Benzyl-3-(dimethylamino)pyrrolidine 1-Benzyl-3-(ethylamino)pyrrolidine 1-Benzyl-3-(methylamino)pyrrolidine 1-Benzyl-3-(trifluoroacetamido)pyrrolidine 3-(tert-Butoxycarbonylamino)pyrrolidine 3-(N-tert-Butoxycarbonyl-N-methylamino)pyrrolidine
Unit Size 5g 5g 5g 5g
5g 5g 5g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
25g 5g 25g 25g 25g 25g 25g 10g 5g 5g 25g 25g 25g 25g
3-Aminopyrrolidines
Product No. Product Name
Unit Size
N,N '-Dibenzyl-3-aminopyrrolidine 3-(Diethylamino)pyrrolidine 3-(Dimethylamino)pyrrolidine N,N '-Dimethyl-3-aminopyrrolidine 3-(Ethylamino)pyrrolidine 3-(Methylamino)pyrrolidine 3-(Trifluoroacetamido)pyrrolidine Hydrochloride
D1964 D1857 D1859 D1965 E0431 M1106 T1247
25g 25g 25g 10g 5g 25g 10g
5g 10g
5g
A1169
A1170
A2323 NH2
O
O
NH C CH3
NH C CH3
. HCl
N
Chiral
N H
A2324
A1167 NH2
A1168
. HCl
C OCH2
N H
O
A1053
NH2
A1054
NH2
NH2
N N H
N H
C OCH2
NH2
. 2HCl
N H
N H
. 2HCl
O
A1173
A1174
B1932
NH2
NH2
N
N
CH2
CH2
B1582
B1580
N CH2
A1171
NHCH3
O NH
N
CH2
CH2
B2921 NH2 N
B2920 O
CH3
C O C CH3
NH
D2193
E0433
CH3
CH3 N CH3
N
CH3
C O C CH3
N H
N CH3
NH2
CH3
C O C CH3 CH3
N H
N H
CH3
M1107
O
CH3
E0434 NHCH2CH3
N H
N H
M1108
T1369
NHCH3 N H
CH2
NHCH2CH3
CH3
C O C CH3 O
N
CH2
CH3
D2149
NHCH2CH3
N
A1172
NHCH3
N
NHCH2CH3
NH C O C CH3 CH3
B1583
B1581
CH3
O
NHCH3 N H
N H
N H
T1366 O
O
NH C CF3
NH C CF3
. HCl
N H
. HCl
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
319
3-Aminopyrrolidines
Product No. Product Name A1169 A1170 A2323 A2324 A1167 A1168 A1053 A1054 A1173 A1174 B1932 B1580 B1581 B1582 B1583 A1171 A1172 B2920 B2921 D2149 D2193 E0433 E0434 M1107 M1108 T1369 T1366
Unit Size
(3R)-(+)-3-Acetamidopyrrolidine (3S)-(-)-3-Acetamidopyrrolidine (R)-3-Amino-1-carbobenzoxypyrrolidine Hydrochloride (S)-3-Amino-1-carbobenzoxypyrrolidine Hydrochloride (3R)-(+)-3-Aminopyrrolidine (3S)-(-)-3-Aminopyrrolidine (3R)-(-)-3-Aminopyrrolidine Dihydrochloride (3S)-(+)-3-Aminopyrrolidine Dihydrochloride (3R)-(-)-1-Benzyl-3-aminopyrrolidine (3S)-(+)-1-Benzyl-3-aminopyrrolidine (3R)-(+)-1-Benzyl-3-(tert-butoxycarbonylamino)pyrrolidine (3R)-(-)-1-Benzyl-3-(ethylamino)pyrrolidine (3S)-(+)-1-Benzyl-3-(ethylamino)pyrrolidine (3R)-(-)-1-Benzyl-3-(methylamino)pyrrolidine (3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine (3R)-(+)-3-(tert-Butoxycarbonylamino)pyrrolidine (3S)-(-)-3-(tert-Butoxycarbonylamino)pyrrolidine (3R)-(+)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine (3S)-(-)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine (3R)-(+)-3-(Dimethylamino)pyrrolidine (3S)-(-)-3-(Dimethylamino)pyrrolidine (3R)-(+)-3-(Ethylamino)pyrrolidine (3S)-(-)-3-(Ethylamino)pyrrolidine (3R)-(+)-3-(Methylamino)pyrrolidine (3S)-(-)-3-(Methylamino)pyrrolidine (3R)-(+)-3-(Trifluoroacetamido)pyrrolidine Hydrochloride (3S)-(-)-3-(Trifluoroacetamido)pyrrolidine Hydrochloride
1g 1g 5g 5g 5g 5g 10g 10g
5g 5g 5g 5g 1g 1g 1g 1g
1g 1g 1g 1g
References 1) 2) 3) 4)
320
Tokyo Tokyo Tokyo Tokyo
Kasei Kasei Kasei Kasei
Kogyo Kogyo Kogyo Kogyo
Co., Co., Co., Co.,
Ltd., Ltd., Ltd., Ltd.,
Jpn. Kokai Tokkyo Koho 2 218664, 1990. Eur. Patent Appl., EP 218249, 1987. Jpn. Kokai Tokkyo Koho 63 41453, 1988. Jpn. Kokai Tokkyo Koho 63 41452, 1988.
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
5g 5g 5g 5g 25g 25g 25g 25g 25g 25g 5g 5g 5g 25g 25g 25g 25g 5g 5g 5g 5g 1g 1g 5g 5g 25g 25g
-Substituted Maleimides, Succinimides & Phthalimides
-Substituted Maleimides, Succinimides & Phthalimides
A0825
B1149 O
N
B1805 O
O
N
-Substituted Maleimides
N
N H
O
N
O
CH2
O
NH2
B1971
B1109
E0482
B1787
O O CH3
H3C O
N
CH2
O CH2CH3
O
N
N
H3CH2C O
O
CH2
N
N
N
O
CH2CH2
N
N
(CH2)6 N
O
O
O
M1962
A5591
N
O
O
P0976 O
O
N
O
CH2Br
N
O
O
O
O
N
O
N
P0900
O
O
N
N
O
O
O N
N
NO2
P1214
S0399
O
O
S0428
O
S0427
O
O
O
O
N
N O C CH2CH2CH2
N
N O C
O
O
O
O N O C
N
O
S0398 O
O
CH3
O
P0778
O
O
N
O
N
O
M0807
O
O O
N
CH2CH2 C OH
N0638
O
Cl
O CH3
CH2CH3
N
Cl
M0881
O O
O
O
O
E0136
O
O
O
O
C1044
B1973
O
O
N
N O C CH2CH2
N
O
O
O
O
O
O
O O
(CH2)5
T1987 O
N
Cl
O Cl
Cl
Product No. Product Name A0825 B1149 B1805 B1971 B1109 E0482
N-(4-Aminophenyl)maleimide N-[4-(2-Benzimidazolyl)phenyl]maleimide N-Benzylmaleimide Bis(3-ethyl-5-methyl-4-maleimidophenyl)methane 4,4'-Bismaleimidodiphenylmethane 1,2-Bis(maleimido)ethane
Unit Size 100mg 50mg 100mg 5g 25g 25g 500g 25g 500g 100mg
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
321
-Substituted Maleimides, Succinimides & Phthalimides
Product No. Product Name B1787 B1973 C1044 E0136 M1962 M0881 M0807 A5591 N0638 P0976 P0778 P0900 P1214 S0398 S0399 S0428 S0427 T1987
Unit Size
1,6-Bismaleimidohexane N-Bromomethyl-2,3-dichloromaleimide N-Cyclohexylmaleimide N-Ethylmaleimide 3-Maleimidopropionic Acid 6,7-Methylenedioxy-4-methyl-3-maleimidocoumarin [for HPLC Labeling] N-Methylmaleimide NAM [=N-(9-Acridinyl)maleimide] [for HPLC Labeling] N-(4-Nitrophenyl)maleimide N,N '-1,3-Phenylenedimaleimide N,N '-1,4-Phenylenedimaleimide N-Phenylmaleimide N-(1-Pyrenyl)maleimide N-Succinimidyl 3-Maleimidobenzoate [Cross-linking Reagent] N-Succinimidyl 4-Maleimidobutyrate [Cross-linking Reagent] N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent] N-Succinimidyl 3-Maleimidopropionate [Cross-linking Reagent] N-(2,4,6-Trichlorophenyl)maleimide
A1819
100mg 5g 25g 25g 1g 100mg 500g 100mg 5g 500g 5g 500g 250mg 1g 1g 1g 1g 25g
1g 1g
5g 200mg 25g 50mg 25g 1g 25g 100mg 100mg 100mg 100mg
B0656
B2205
O
O
-Substituted Succinimides
B3433
CH3S
O
N Boc
O
Boc
C2334
O
CH3
O O
HN
N N H
O
Cbz
CH2O C O N
CH2O C O N
O
O
O
O
O O
O
N
N O C O N
O
Cl
O
F0239
O
H0623 B0249 O O
O
N
CH2O C O N
O
CH2CH3
O
P1359
O
O
O
N
S0431
S0814
O
OH
O
2
I0074
CH2O C O N
D1662
O
O
O
O
Cbz
O
O
N O C (CH2)6 C O N
N O C CH2CH2S
O CH3 HN
O
E0175
N
O
N
O
Cl
O Boc
O
C0291
O
D3895
CH3 O
Boc
O
D2473
O
HN
O
O
O HN
O N
C1131 O
O
O
C1124
O O
Br
N
N
C2353 O
C1298 CH3 O
O
Br
O N
. HCl
B3435
O O
HN
O
NH2
B3414 O
N
S0491 O
O
O
O O
N I
O
N
O
O
HN
O
O
CH3 C SCH2 C O N
CH2 CH
C O N
NH
H
H S
O
(CH2)4
O O C O N
O O
322
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
-Substituted Maleimides, Succinimides & Phthalimides
S0503
S0808
D2255 O
O
C
NH(CH2)5 C O N N N
O
O CH3
CH3
S0428 O N
N O C CH2CH2
N
O
O
O
T1513 CH3
O CH3
O CH3
O O C O N CH3 O
NO2
O
N O C
N
N O C CH2CH2CH2
N
O
O
O
O
O
O O2N
O
CH2
S0808 D2255 S0398 S0399 S0428 S0427 S0812 A5522 S0819 S0599 T1513 T2224 T2591
O
C O N
CH3
N
S
SCH2CH2 C O N
O
O
O
T2591
O N O C
O
O
CH2 C C O N
O
CCl3CHO C O N
S0819
O
N(CH3)2 N(CH3)2
O
BF4
(CH3)3SiCH2CH2O C O N
O
Product No. Product Name A1819 B0656 B2205 B3433 B3414 B3435 C2353 C1124 C2334 C1298 C1131 C0291 D1662 D2473 D3895 E0175 F0239 H0623 B0249 I0074 P1359 S0431 S0814 S0491 S0503
O O
A5522
T2224 O
Cl
(CH2)5 NH
O
O O
S0599
O
N O C
S0812
O
O
O
O O
NO2
S0427
(CH2)5
O
O2N
O
O
OCH2
SO2N(CH3)2
N O C
S0399
O CH2CH2 C O N
O
O
O
S0398
O
O
N-Aminosuccinimide Hydrochloride N-Bromosuccinimide N-(tert-Butoxycarbonyl)-O-benzyl-L-serine N-Succinimidyl Ester N-(tert-Butoxycarbonyl)-L-methionine N-Succinimidyl Ester N-(tert-Butoxycarbonyl)-D-proline Succinimidyl Ester Nα-(tert-Butoxycarbonyl)-L-tryptophan N-Succinimidyl Ester N-Carbobenzoxy-L-leucine N-Succinimidyl Ester N-Carbobenzoxyoxysuccinimide N-Carbobenzoxy-L-valine Succinimidyl Ester Carbonic Acid 2-Bromobenzyl Succinimidyl Ester N-(2-Chlorobenzyloxycarbonyloxy)succinimide N-Chlorosuccinimide Di(N-succinimidyl) Carbonate Di(N-succinimidyl) 3,3'-Dithiodipropionate [Cross-linking Reagent] Di(N-succinimidyl) Suberate N-Ethylsuccinimide N-[(9H-Fluoren-9-ylmethoxy)carbonyloxy]succinimide N-Hydroxysuccinimide N-Hydroxysuccinimide [Coupling Reagent for Peptide] N-Iodosuccinimide N-Phenylsuccinimide N-Succinimidyl S-Acetylthioglycolate [Cross-linking Reagent] N-Succinimidyl Acrylate N-Succinimidyl D-Biotinate Succinimidyl 6-[[7-(N,N-Dimethylaminosulfonyl)-2,1,3-benzoxadiazol4-yl]amino]hexanoate Succinimidyl 4-[3,5-Dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyrate N-Succinimidyl 6-(2,4-Dinitroanilino)hexanoate N-Succinimidyl 3-Maleimidobenzoate [Cross-linking Reagent] N-Succinimidyl 4-Maleimidobutyrate [Cross-linking Reagent] N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent] N-Succinimidyl 3-Maleimidopropionate [Cross-linking Reagent] N-Succinimidyl Methacrylate N-Succinimidyl 4-Nitrophenylacetate [for HPLC Labeling] N-Succinimidyl 3-(2-Pyridyldithio)propionate Succinimidyl (2R)-6-(Tetrahydro-2H-pyran-2-yloxy)-2,5,7,8-tetramethylchroman2-carboxylate N-(1,2,2,2-Tetrachloroethoxycarbonyloxy)succinimide N,N,N ',N '-Tetramethyl-O-(N-succinimidyl)uronium Tetrafluoroborate N-[2-(Trimethylsilyl)ethoxycarbonyloxy]succinimide
O
Unit Size 25g
1g 100g 1g 1g
25g
25g 5g 1g 1g 5g 25g 5g
25g 5g 1g
100mg 100mg 100mg 100mg 5g
1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 500g 5g 5g 5g 5g 5g 250g 5g 10g 10g 500g 25g 5g 5g 25g 25g 500g 25g 100g 25g 5g 5g 100mg 100mg 100mg 1g 1g 1g 1g 1g 25g 1g 100mg 50mg 10g 5g 5g
323
-Substituted Maleimides, Succinimides & Phthalimides
A0108
A1447 O
A1561 O
O
O
H2N
N C CH3
-Substituted Phthalimides
N OCH2CH O
O
A0843
B1997 O
B1394
N NH2
O
O
B1697
O
N CH2Br
N CH2CH2Br
O
B2707
O
O
N (CH2)3CH2Br
O
B3443
P1192
O
N CH2
O
O
B0597
O
N CH3
CH2
B1328
O
O
B1881 O
O
Br N CH3
N
Br
N Br
O
O
B0736
A5503
(CH2)3CH3
CH3 O
C0802
N CH2Cl
O
AcO AcO
N CH2
G0327
OAc BnO O O O N O
N CH2
O O O N O
N CH2OH O
O
H0933
O
I0738
O
O
O O
N
N OH O
Ph
O O
N
O
N OH
OCH3
Ph
O O
O N O
OCH3
OH
O
M1609
O O O
N CH
N
O
M1598 OBn O
AcO BnO
(CH2)8OH
O
M1834
OH
O O O
N
O
OCH3
M1479 OH O
HO BnO
Ph
O O
CH3 CH3
O
M1610
O O BnO
OCH3
O
N CH2CH2OH
O2N
324
O O
O O
H0395
O
O OAc
H0648
O
H0834
OAc Ph O
AcO
O
O
O
H1036
OCH2CH3
O
N CH2
OBn
N C OCH2CH3
H0245
O OCH3
AcO
O
G0328
OBn O O
P
OCH2CH3
O
O
G0311 O
O
N S
O
Cl
O
C0683
O
N Cl
N
N CH2Cl O
P1193
O
O
O2N O
C1452
G0299
O
CH3
N O C O C CH3
O
C1958
O O
N
O
A5504
O
N CH2CH2CH CH2
O
O
C1573 O
N CH2CH2CH2Br
N
O
OCH3
O O HO
O O O
N
OCH3
O
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
-Substituted Maleimides, Succinimides & Phthalimides
M1615
M1480 OBn O
HO BnO
O N
O
OCH3
M1310
O N
O
O
M1649
O
OAc O
AcO AcO
M0299
OCH3
O
N CH3
O
N0574
O0365
P1235
O
O
O
P1254
O
SCH3 N
O
N CH3
O
OAc O
AcO AcO
O2N
O
P0403 O
O
O2N
N
N
N
O
O
N S
O
P1229
P1180 O
N CH2CH
N CH2
OCH2CH3
O
C CH3
P0620
P0963
CH3 O N CH
C OCH2CH3
C OH
N
O
P1227
P0338
O
T2047
N CH2
O
O
OH
O N
C OH
N
O
O
T2054
T2055
F
O
N CH3
R
R
O O H
R
. 2 CH3
O
Rh Rh O O O H R
R
O
Cl
O Cl Cl
O
H
. 2 CH3
O
Cl
C OCH2CH3
O O O
R
H
O
. 2 CH3
R'
H R
R
O
R=
Cl
R
C OCH2CH3
Cl
. 2 CH3
O
O
Cl
C OCH2CH3
O O O
R
R
O
O
Rh
H R
R'=
N
R=
CH2
O H R'
O
. CH3
C OCH2CH3
T1526 R H
H OO
Rh Rh
N
O H
O Cl
H R' OO
O
H
R
O
R
T2661 H
H OO
Rh Rh
N
R=
O
R
O
R
C OCH2CH3
Rh O O O
N
R=
O
R H
H OO
O
O
T2660
R O
O
R
Rh
H
O
T2659 H
OO
Rh O O O
N
R=
H
O
O
O
Rh
H
O
T2658
R
OO
Rh O O O
R
F
H
H
O
R' H
R
H
O
T1551
R
O
F
OAc N
O
CH2CH2 C OH O
O
T2421 F
OAc O
AcO AcO
N CH C OH
O
O O
O
O
O
O
O
O O
O
O
O
O
C OCH2CH3
N CH
O
P1789
O
O OCH2CH3
O
P0695
O
O
N H
O
O
P1203
NK
N
O
R
O
O F
R=
F O
. 2 CH3
O
F
C OCH2CH3
H OO
Rh Rh
N
O H
F
O O O
R H
R
O
O R R=
O
F F F
. 2 CH3
O
O
F
CBr
N
N
O H
Cl Cl O
3
C OCH2CH3
V0065 O N CH
CH2
O
Product No. Product Name A0108 A1447 A1561 A0843 B1997 B1394
N-Acetylphthalimide N-Allyloxyphthalimide 4-Amino-N-methylphthalimide N-Aminophthalimide N-Benzylphthalimide N-(4-Bromobutyl)phthalimide
Unit Size 5g 5g 5g 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 25g 25g 25g 25g 25g
325
-Substituted Maleimides, Succinimides & Phthalimides
Product No. Product Name B0597 P1192 B3443 B2707 B1697 B1328 B1881 B0736 C1573 A5503 A5504 C1958 C0802 C1452 P1193 C0683 G0311 G0299 G0327 G0328 H0245 H0648 H1036 H0834 H0395 H0933 I0738 M1834 M1598 M1609 M1610 M1479 M1615 M1480 M1310 M0299 M1649 N0574 O0365 P1254 P1235 P0403 P1229 P1203 P1180 P0695 P1789 P0620 P0963 P1227 P0338 T2047 T2421 T2054 T2055 T1551 T2658 T2659 T2660 T2661 T1526 V0065
326
N-(2-Bromoethyl)phthalimide N-(Bromomethyl)phthalimide 4-Bromo-N-methylphthalimide N-(4-Bromophenyl)phthalimide N-Bromophthalimide N-(3-Bromopropyl)phthalimide N-(3-Buten-1-yl)phthalimide N-Butylphthalimide Carbonic Acid tert-Butyl Phthalimido Ester N-Chloromethyl-4-nitrophthalimide [for HPLC Labeling] N-Chloromethylphthalimide [for HPLC Labeling] N-(4-Chlorophenyl)phthalimide N-Chlorophthalimide N-(Cyclohexylthio)phthalimide Diethyl (Phthalimidomethyl)phosphonate N-Ethoxycarbonylphthalimide [for Peptide Synthesis] Gal[2346Ac]β(1-3)GlcNPhth[46Bzd]-β-MP GlcNPhth[346Ac]β(1-3)Gal[246Bn]-β-MP (R)-N-Glycidylphthalimide (S)-N-Glycidylphthalimide N-(2-Hydroxyethyl)phthalimide N-Hydroxymethylphthalimide N-Hydroxy-4-nitrophthalimide N-(8-Hydroxyoctyl)phthalimide N-Hydroxyphthalimide (S)-(+)-2-Hydroxy-4-phthalimidobutyric Acid N-Isopropylphthalimide 4-Methoxyphenyl 4-O-Acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 4-Methoxyphenyl 3-O-Allyl-4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranoside 4-Methoxyphenyl 3-O-Benzyl-4,6-O-benzylidene-2-deoxy-2-phthalimidoβ-D-glucopyranoside 4-Methoxyphenyl 3-O-Benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 4-Methoxyphenyl 4,6-O-Benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranoside 4-Methoxyphenyl 3,6-Di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 4-Methoxyphenyl 3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside N-Methyl-4-nitrophthalimide N-Methylphthalimide Methyl 3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 4-Nitro-N-phenylphthalimide N-(4-Oxocyclohexyl)phthalimide N-(Phenylthio)phthalimide Phthalimide DBU Salt Phthalimide Potassium Salt 2-Phthalimidoacetaldehyde Diethyl Acetal Phthalimidoacetone Phthalimidomalonic Acid Diethyl Ester Phthaloyl-DL-alanine N-Phthaloyl-DL-glutamic Anhydride N-Phthaloyl-L-glutamic Anhydride N-Phthaloylglycine N-Phthaloyl-L-phenylalanine Phthalyl-DL-glutamic Acid 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranose 3,4,5,6-Tetrafluoro-N-methylphthalimide Tetrakis[N-phthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-phthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-phthaloyl-(S)-phenylalaninato]dirhodium Ethyl Acetate Adduct Tetrakis[N-tetrachlorophthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrachlorophthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrafluorophthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrafluorophthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct 4,4',4''-Tris(4,5-dichlorophthalimido)trityl Bromide [Protecting Reagent for Primary Alcohol] N-Vinylphthalimide
Unit Size 25g 5g 5g 5g 5g 25g
500g 25g 25g 25g 25g 500g 5g 25g 5g 1g 5g 5g 5g 25g 500g 25g 500g 5g 25g 25g 500g 1g 5g Price on request 5g 25g 5g 25g 25g 500g 25g 250g 5g 1g 25g 500g 5g 25g 1g 5g 1g 5g 1g Price on request 5g 1g 5g 5g 25g 25g 1g 5g 25g 5g 25g 5g 25g 25g 25g 500g 25g 25g 5g 10g 25g 5g 25g 1g 5g 25g 500g 5g 5g 25g 5g 25g 5g 25g 100mg 100mg 100mg 50mg 100mg 50mg 100mg 1g 5g 25g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
1,4-Disubstituted Cyclohexanes
1,4-Disubstituted Cyclohexanes
A1278
4-Substituted Cyclohexanecarboxylic Acids A1656
B3248
A1448
4-Amino Substituted B3249
O
O
C OH
C OH
NH2
NH2
B3250
C2036
O
O
O
O
O
C OH
C OH
C OH
C OH
C OH
O HN C OC(CH3)3
NH2
HN C OC(CH3)3 O
O
M1985
HN C OC(CH3)3
NH C OCH2
O
M1986 O
O
C OCH3
C OCH3
. HCl
. HCl NH2
NH2
Product No. Product Name A1278 A1448 A1656 B3248 B3249 B3250 C2036 M1985 M1986
E0838
4-Hydroxy Substituted
Unit Size
4-Aminocyclohexanecarboxylic Acid (cis- and trans- mixture) cis-4-Aminocyclohexanecarboxylic Acid trans-4-Aminocyclohexanecarboxylic Acid 4-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid (cis- and trans- mixture) cis-4-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid trans-4-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid trans-4-(Carbobenzoxyamino)cyclohexanecarboxylic Acid Methyl cis-4-Aminocyclohexanecarboxylate Hydrochloride Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride
H0960
H0980
5g 5g 5g 5g
1g
5g 1g
O
O
O
C OCH2CH3
C OH
C OH
C OH
OH
OH
OH
OH
Ethyl trans-4-Hydroxycyclohexanecarboxylate 4-Hydroxycyclohexanecarboxylic Acid (cis- and trans- mixture) cis-4-Hydroxycyclohexanecarboxylic Acid trans-4-Hydroxycyclohexanecarboxylic Acid
25g 25g 25g 25g 5g 5g 25g 5g 5g
H1175
O
Product No. Product Name E0838 H0960 H0980 H1175
1g 1g
Unit Size 25g 5g 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 250g 25g 25g
327
1,4-Disubstituted Cyclohexanes
B2986
B1136
4-Alkyl Substituted
B1285
B2631
O
O
O
O
C OH
C OH
C OH
C OH
CH3 C CH3
(CH2)3CH3
(CH2)3CH3
B3037
I0664
M1621
CH3 C CH3
CH3
M1783
CH3
P0944
O
O
O
O
O
C OH
C OH
C OH
C OH
C OH
CH3
CH3
CH3 C CH3
CH3
CH3
P1656
CH3
P0943
T2417
T2423
(CH2)4CH3
T2424
O
O
O
O
O
C OH
C OH
C OH
C OH
C OH
CH2CH2CH3
CH2CH2CH3
CF3
CF3
CF3
Product No. Product Name B2986 B1136 B1285 B2631 B3037 I0664 M1621 M1783 P0944 P1656 P0943 T2417 T2423 T2424
Unit Size
4-Butylcyclohexanecarboxylic Acid (cis- and trans- mixture) trans-4-Butylcyclohexanecarboxylic Acid 4-tert-Butylcyclohexanecarboxylic Acid (cis- and trans- mixture) cis-4-tert-Butylcyclohexanecarboxylic Acid trans-4-tert-Butylcyclohexanecarboxylic Acid trans-4-Isopropylcyclohexanecarboxylic Acid 4-Methylcyclohexanecarboxylic Acid (cis- and trans- mixture) trans-4-Methylcyclohexanecarboxylic Acid trans-4-Pentylcyclohexanecarboxylic Acid 4-Propylcyclohexanecarboxylic Acid (cis- and trans- mixture) trans-4-Propylcyclohexanecarboxylic Acid 4-(Trifluoromethyl)cyclohexanecarboxylic Acid (cis- and trans- mixture) cis-4-(Trifluoromethyl)cyclohexanecarboxylic Acid trans-4-(Trifluoromethyl)cyclohexanecarboxylic Acid A2121
A0236
5g 5g 5g 5g
25g 25g 25g 25g 5g 25g 25g 25g 25g 25g 25g 5g 5g 5g
5g 5g 5g 5g 5g 1g 1g
B3251
B3253
O
O
O
O
C OH
C OH
C OH
C OH
CH2NH2
CH2NH2
Miscellaneous CH2NH C OC(CH3)3
C0788
C0789
C0475
CH2NH C OC(CH3)3
O
D3768
O
D3639
O
O
O
O
O
C OH
C OH
C OH
C OCH2CH CH2
C OCH2CH3
C OH
C OH
C OH
C OCH2CH CH2
C OCH2CH3
O
O
O
O
O
C1154
H1015
H1242
H1243
M1988
O
O
O
O
O
C OCH3
C OH
C OH
C OH
C OCH3
CH2OH
CH2OH
CH2OH
CH2NH2
. HCl
C OCH3 O
328
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
1,4-Disubstituted Cyclohexanes
Product No. Product Name A2121 A0236 B3251 B3253 C0788 C0789 C0475 D3768 D3639 C1154 H1015 H1242 H1243 M1988
Unit Size
4-(Aminomethyl)cyclohexanecarboxylic Acid (cis- and trans- mixture) trans-4-(Aminomethyl)cyclohexanecarboxylic Acid 4-(tert-Butoxycarbonylaminomethyl)cyclohexanecarboxylic Acid (cis- and trans- mixture) trans-4-(tert-Butoxycarbonylaminomethyl)cyclohexanecarboxylic Acid 1,4-Cyclohexanedicarboxylic Acid (cis- and trans- mixture) cis-1,4-Cyclohexanedicarboxylic Acid trans-1,4-Cyclohexanedicarboxylic Acid Diallyl 1,4-Cyclohexanedicarboxylate (cis- and trans- mixture) Diethyl trans-1,4-Cyclohexanedicarboxylate Dimethyl 1,4-Cyclohexanedicarboxylate (cis- and trans- mixture) 4-(Hydroxymethyl)cyclohexanecarboxylic Acid (cis- and trans- mixture) cis-4-(Hydroxymethyl)cyclohexanecarboxylic Acid trans-4-(Hydroxymethyl)cyclohexanecarboxylic Acid Methyl trans-4-(Aminomethyl)cyclohexanecarboxylate Hydrochloride
A1278
4-Substituted Cyclohexylamines
A1656
M1985
4-Carboxy Substituted
5g 25g 25g 25g 25g 5g 25g 5g 5g 1g
A1448 O
O
C OH
C OH
NH2
NH2
M1986
O
O
O
C OH
C OCH3
C OCH3
NH2
NH2
. HCl
. HCl NH2
Product No. Product Name A1278 A1448 A1656 M1985 M1986
5g 25g 5g 25g 500g 100g 500g 250g 25g 500g 25g 25g 5g 5g
5g
Unit Size
4-Aminocyclohexanecarboxylic Acid (cis- and trans- mixture) cis-4-Aminocyclohexanecarboxylic Acid trans-4-Aminocyclohexanecarboxylic Acid Methyl cis-4-Aminocyclohexanecarboxylate Hydrochloride Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride
1g 1g
5g 5g 5g 1g
25g 25g 25g 5g 5g
A1160 OH
4-Hydroxy Substituted
NH2
Product No. Product Name A1160
Unit Size
trans-4-Aminocyclohexanol
B1084
M1117 NH2
4-Alkyl Substituted
25g
M1780 NH2
500g
M0957 NH2
NH2
. HCl CH3 C CH3 CH3
CH3
CH3
CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
329
1,4-Disubstituted Cyclohexanes
Product No. Product Name
Unit Size
B1084 M1117 M1780 M0957
25ml
4-tert-Butylcyclohexylamine (cis- and trans- mixture) 4-Methylcyclohexylamine (cis- and trans- mixture) trans-4-Methylcyclohexylamine 4-Methylcyclohexylamine Hydrochloride
A2288
C0814
5g
C1798
250ml 25ml 25g 25g
C1426
CH2CH2OH
NH2
NH2
NH2
NH2
NH2
NH2
NH2
Miscellaneous
Product No. Product Name A2288 C0814 C1798 C1426
Unit Size
4-Aminocyclohexaneethanol (cis- and trans- mixture) 1,4-Cyclohexanediamine (cis- and trans- mixture) cis-1,4-Cyclohexanediamine trans-1,4-Cyclohexanediamine
1g 5ml 5g 5g
E0838
4-Substituted Cyclohexanols
H0980
4-Carboxy Substituted
H0960 O
O
C OCH2CH3
C OH
OH
OH
H1175 O
O
C OH
C OH
OH
OH
Product No. Product Name E0838 H0960 H0980 H1175
Unit Size
Ethyl trans-4-Hydroxycyclohexanecarboxylate 4-Hydroxycyclohexanecarboxylic Acid (cis- and trans- mixture) cis-4-Hydroxycyclohexanecarboxylic Acid trans-4-Hydroxycyclohexanecarboxylic Acid
A1617
A1162 OH
4-Amino Substituted
NH
C CH3 O
330
25g 5g 5g
A1160 OH
NH
C CH3 O
4-Acetamidocyclohexanol (cis- and trans- mixture) trans-4-Acetamidocyclohexanol trans-4-Aminocyclohexanol trans-4-(tert-Butoxycarbonylamino)cyclohexanol
5g 250g 25g 25g
B3564 OH
Product No. Product Name A1617 A1162 A1160 B3564
5g 25ml 25g 25g
NH2
OH
NH C OC(CH3)3 O
Unit Size 25g 1g
25g 25g 500g 5g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
1,4-Disubstituted Cyclohexanes
A1926
A2315
4-Alkyl Substituted B1270
OH
OH
CH2(CH2)3CH3
CH2(CH2)3CH3
(CH2)3CH3
B1271
E0366 OH
CH3 C CH3
CH3
CH3
I0782
M0196
CH3
P1882
E0768
OH
CH3 C CH3 CH3
I0780
OH
OH
CH2CH3
CH2CH3
M0353
OH
CH3
B0383
OH
OH
CH3 C CH3
B1930
M0354
OH
CH3
CH3
P1874
OH
OH
OH
OH
CH3
CH3
CH3
CH2CH2CH3
T2706 OH
OH
CH2CH2CH3
CF3
Product No. Product Name A1926 A2315 B1930 B0383 B1270 B1271 E0366 E0768 I0780 I0782 M0196 M0353 M0354 P1874 P1882 T2706
Unit Size
4-Amylcyclohexanol (cis- and trans- mixture) trans-4-Amylcyclohexanol 4-Butylcyclohexanol (cis- and trans- mixture) 4-tert-Butylcyclohexanol (cis- and trans- mixture) cis-4-tert-Butylcyclohexanol trans-4-tert-Butylcyclohexanol 4-Ethylcyclohexanol (cis- and trans- mixture) trans-4-Ethylcyclohexanol 4-Isopropylcyclohexanol (cis- and trans- mixture) trans-4-Isopropylcyclohexanol 4-Methylcyclohexanol (cis- and trans- mixture) cis-4-Methylcyclohexanol trans-4-Methylcyclohexanol 4-Propylcyclohexanol (cis- and trans- mixture) trans-4-Propylcyclohexanol 4-(Trifluoromethyl)cyclohexanol (cis- and trans- mixture)
A2266
C0482
5g 5g 25g 1g 1g
25ml
1g
C2319
25g 1g 25g 500g 5g 5g 25ml 5g 5g 1g 500ml 5ml 5ml 5g 1g 5g
C2320
OH
OH
OH
OH
CH2CH2NH2
OH
OH
OH
Miscellaneous
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
331
1,4-Disubstituted Cyclohexanes
H1253
H1257
H1258
OH
OH
OH
CH2CH2OH
CH2OH
CH2OH
Product No. Product Name A2266 C0482 C2319 C2320 H1253 H1257 H1258
Unit Size
4-(2-Aminoethyl)cyclohexanol (cis- and trans- mixture) 1,4-Cyclohexanediol (cis- and trans- mixture) cis-1,4-Cyclohexanediol trans-1,4-Cyclohexanediol 4-(2-Hydroxyethyl)cyclohexanol (cis- and trans- mixture) 4-(Hydroxymethyl)cyclohexanol (cis- and trans- mixture) trans-4-(Hydroxymethyl)cyclohexanol
B1083
25g
1g 100g 1g 1g 5g 1g
C0479
5g 500g 200mg 5g 5g 25g 5g
C2234
CH2NH2
CH2OH
CH2OH
CH2NH2
CH2OH
CH2OH
Others
C1133
C1135 O
CH2O C CH
O CH2O C CH
D0271
CH2CH3 (CH2)3CH3
CH2CH3 (CH2)3CH3
C1136 O
CH2O C CH2CH
O CH2O C CH2CH
E0424
CH3 CH3
D0700
CH2O C
CH3
O
CH3
CH2O C
(CH2)10CH3
(CH2)10CH3
I0284
CH3
CH2CH3
CH3
CH3
332
CH3
CH3
CH3
CH3
I0285
M1412 CH3
CH3
CH3
CH3
Product No. Product Name B1083 C0479 C2234 C1133 C1135 C1136 D0700 D1715 D0271 E0424 I0284 I0285 M1412
D1715
O
1,4-Bis(aminomethyl)cyclohexane (cis- and trans- mixture) 1,4-Cyclohexanedimethanol (cis- and trans- mixture) trans-1,4-Cyclohexanedimethanol 1,4-Cyclohexanedimethanol Bis(2-ethylhexanoate) 1,4-Cyclohexanedimethanol Diisovalerate 1,4-Cyclohexanedimethanol Dilaurate 1,4-Dimethylcyclohexane (cis- and trans- mixture) cis-1,4-Dimethylcyclohexane trans-1,4-Dimethylcyclohexane 1-Ethyl-4-methylcyclohexane (cis- and trans- mixture) cis-1-Isopropyl-4-methylcyclohexane trans-1-Isopropyl-4-methylcyclohexane 4-Methyl-1-cyclohexanemethanol (cis- and trans- mixture)
CH3
CH3
CH3
CH2OH
Unit Size 25g 5g
25ml 5ml 5ml
5g
25g 500g 25g 25g 1g 1g 500ml 25ml 25ml 1ml 5ml 1ml 25g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Monofunctional & α, ω-Bifunctional Alkanes
Monofunctional & α, ω-Bifunctional Alkanes Monofunctional Alkanes / H-(CH2)n-X x
n 1
―OH
―COOH
―NH2
―Br
―Cl
M0097
A2035
M0137
B1618
――
2
――
P0500
E0055
B0588
C0164
3
P0491
B0754
P0520
B0638
C0266
4
B0228
V0003
B0707
B0560
C0142
5
P0055
H0105
A0445
B0628
C0237
6
H0130
H0030
H0134
B0600
C0184
7
H0033
O0027
H0045
B0598
C0182
8
O0212
N0288
O0045
B0626
C0236
9
N0292
D0017
N0297
B0933
C0233
10
D0031
U0004
D0033
B0583
C0600
11
U0005
L0011
A0761
B0934
C0599
12
D0978
T0412
D0980
B0587
C0163
13
T0803
M0476
A0762
B0935
C2213
14
T0084
P0035
T0090
B0233
C0622
15
P0036
P0002
A0763
B0936
―― C0183
16
H0071
H0019
H0074
B0599
17
H0018
S0163
A0764
B0937
――
18
O0006
N0283
O0014
B0625
C0235
19
N0284
E0006
A0765
――
――
20
E0004
H0010
――
B0391
C0774
―NH2
―Br
―Cl
α,ω-Bifunctional Alkanes / X-(CH2)n-X x
―OH
―COOH
1
――
M0028
――
D0192
D0529
2
E0105
S0100
E0077
D0180
D0310
3
P0486
G0069
D0114
D0202
D0399
4
B0680
A0161
D0239
D0176
D0349
n
5
P0050
P0435
D0108
D0198
D0390
6
H0099
O0023
D0095
D0185
D0372
7
H0028
A1318
D0094
D2119
D1030
8
O0024
S0022
D0107
D1064
D1012
9
N0287
N0333
D0106
D1746
――
10
D0014
D0013
D0085
D0179
D0247
11
――
T0021
D2075
D2487
――
12
D0969
T0704
D0091
D1346
――
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
333
ω-Functional Alkanols, Carboxylic Acids, Amines & Halides
ω-Functional Alkanols, Carboxylic Acids, Amines & Halides X−(CH2)n−OH Product No. Product Name C0270 C0144 C0815 C0801 B0590 B0641 B1885 B1848 B1822 B1852 B1729 B1785 B1730 B1477 B1731 I0391
Unit Size
3-Chloro-1-propanol 4-Chloro-1-butanol (contains varying amounts of Tetrahydrofuran) 5-Chloro-1-pentanol 6-Chloro-1-hexanol 2-Bromoethanol 3-Bromo-1-propanol 4-Bromo-1-butanol (contains varying amounts of Tetrahydrofuran) 5-Bromo-1-pentanol 6-Bromo-1-hexanol 7-Bromo-1-heptanol 8-Bromo-1-octanol 9-Bromo-1-nonanol 10-Bromo-1-decanol 11-Bromo-1-undecanol 12-Bromo-1-dodecanol 2-Iodoethanol (stabilized with Copper chip)
25g 25g 5ml 25g 25g 25g 5g 5g 5g 1g 5g 5g 5g 5g 5g
500g 500g 25ml 500g 500g 250g 25g 25g 25g 5g 25g 25g 25g 25g 25g 25g
CH2=CH(CH2)n−OH Product No. Product Name A0218 B0236 P1243 H0653 H0949 O0280 N0650 D1892 U0047
Allyl Alcohol 3-Buten-1-ol 4-Penten-1-ol 5-Hexen-1-ol 6-Hepten-1-ol 7-Octen-1-ol 8-Nonen-1-ol 9-Decen-1-ol 10-Undecen-1-ol
Unit Size 10ml 10ml
25ml 25ml 25ml 25ml 5g 5ml 5g 25ml 25ml
500ml 500ml 250ml 250ml 25g 25ml 25g 500ml 500ml
H2N−(CH2)n−OH Product No. Product Name A0297 A0298 A0438 A0407 A1013 A0875 A1027 A1522 A1523 A1524
334
2-Aminoethanol 2-Aminoethanol Hydrochloride 3-Amino-1-propanol 3-Amino-1-propanol Hydrochloride 4-Amino-1-butanol 5-Amino-1-pentanol 6-Amino-1-hexanol 8-Amino-1-octanol 10-Amino-1-decanol 12-Amino-1-dodecanol
Unit Size 25g 25g 25g 5g 25g 5g 1g 1g 1g
500g 500g 500g 25g 25g 250g 25g 5g 5g 5g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
ω-Functional Alkanols, Carboxylic Acids, Amines & Halides
X−(CH2)n−COOH Product No. Product Name C2123 C0276 C0651 C0309 C1507 B0531 B0645 B1279 B1169 B1290 B3671 B1675 B2323 B2264 B0389 I0071
Unit Size
Chloroacetic Acid 3-Chloropropionic Acid 4-Chlorobutyric Acid 5-Chlorovaleric Acid 6-Chlorohexanoic Acid Bromoacetic Acid 3-Bromopropionic Acid 4-Bromobutyric Acid 5-Bromovaleric Acid 6-Bromohexanoic Acid 7-Bromoheptanoic Acid 8-Bromooctanoic Acid 9-Bromononanoic Acid 10-Bromodecanoic Acid 11-Bromoundecanoic Acid 3-Iodopropionic Acid
25g 25g 25g 5g 25g 25g 10g 25g 10g 1g 5g 25g 5g
500g 500g 500g 25g 25g 500g 500g 25g 25g 250g 5g 25g 5g 25g 500g 25g
CH2=CH(CH2)n−COOH Product No. Product Name A0141 B0694 P0645 H0875 D1932 U0007 T1211
Unit Size
Acrylic Acid (stabilized with MEHQ) 3-Butenoic Acid 4-Pentenoic Acid 5-Hexenoic Acid 9-Decenoic Acid 10-Undecenoic Acid 22-Tricosenoic Acid
25g 25g 5g 5ml 25g 100mg
500g 250g 25ml 25g 25ml 500g 1g
H2N−(CH2)n−COOH Product No. Product Name G0099 G0103 A0180 A0282 A0663 A0436 A0312 A0311 A0932
Glycine Glycine Hydrochloride β-Alanine 4-Aminobutyric Acid 5-Aminovaleric Acid 5-Aminovaleric Acid Hydrochloride 6-Aminohexanoic Acid 7-Aminoheptanoic Acid 12-Aminolauric Acid
Unit Size 25g 25g 25g 25g 5g
1g
25g 5g 25g
500g 500g 500g 500g 25g 1g 500g 25g 500g
HO−(CH2)n−COOH Product No. Product Name
Unit Size
G0110 G0196 H0297
Glycolic Acid (ca. 70% in Water, ca. 12mol/L) Glycolic Acid 3-Hydroxypropionic Acid (contains varying amounts of 3,3'-Oxydipropionic Acid)
25g 25g
500g 500g
(ca. 30% in Water, ca. 3.6mol/L)
H0676 H0675
15-Hydroxypentadecanoic Acid 16-Hydroxyhexadecanoic Acid
10g 1g 1g
25g 5g 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
335
ω-Functional Alkanols, Carboxylic Acids, Amines & Halides
X−(CH2)n−NH2 Product No. Product Name C0851 C1062 B0591 B1263
Unit Size
2-Chloroethylamine Hydrochloride 3-Chloropropylamine Hydrochloride 2-Bromoethylamine Hydrobromide 3-Bromopropylamine Hydrobromide
25g 25g 25g 25g
500g 500g 500g 500g
CH2=CH(CH2)n−NH2 Product No. Product Name
Unit Size
A0219 A0226
25ml 25g
Allylamine Allylamine Hydrochloride
500ml 500g
X−(CH2)n−Cl Product No. Product Name B0573 B0572 B0575 B1345 B1476 B1998 B3537 C1179 C1190 C1037
Unit Size
Bromochloromethane 1-Bromo-2-chloroethane 1-Bromo-3-chloropropane 1-Bromo-4-chlorobutane 1-Bromo-5-chloropentane 1-Bromo-6-chlorohexane 1-Bromo-7-chloroheptane Chloroiodomethane (stabilized with Copper chip) 1-Chloro-2-iodoethane (stabilized with Copper chip) 1-Chloro-3-iodopropane (stabilized with Copper chip)
25g 25g 25g 25g 25g 25g 1g
500g 500g 500g 500g 25g 500g 5g 100g 5g 25g
CH2=CH(CH2)n−X Product No. Product Name C0274 V0032 B0643 B0920 B1474 B2106 B2849 B3576 B2816 I0070
336
Allyl Chloride Vinyl Bromide (stabilized with MEHQ) Allyl Bromide 4-Bromo-1-butene 5-Bromo-1-pentene 6-Bromo-1-hexene 10-Bromo-1-decene 11-Bromo-1-undecene 18-Bromo-1-octadecene Allyl Iodide (stabilized with Copper chip)
Unit Size 25ml
10g
25g 25g 5g 5g 1g 1g
500ml 100g 500g 250g 25g 25g 5g 5g 5g 25g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Quaternary Ammonium Compounds
Quaternary Ammonium Compounds R1 R2 N R4 R
X
3
X=F, Cl, Br, I, OH, etc.
Fluoride Chloride Bromide
Iodide Hydroxide Others
Fluorides Product No. Product Name T1339 T1338 T1125
Tetrabutylammonium Fluoride (70-75% in Water) Tetrabutylammonium Fluoride (1mol/L in Tetrahydrofuran) Tetrabutylammonium Fluoride (1mol/L in Tetrahydrofuran) [for Catalyst of acylation, silylation
T1037
Tetrabutylammonium Fluoride Hydrate [for Catalyst of acylation, silylation and cleavage of
T0838 T2027 T2026
Tetraethylammonium Fluoride Hydrate Tetraethylammonium Fluoride Tetrahydrofluoride Tetraethylammonium Fluoride Trihydrofluoride
and cleavage of Silyl Ether] silyl ether]
Unit Size 25ml
25g 100ml
500g 500ml
25ml
100ml
25g 5g
250g 25g 10g 10g
Chlorides Product No. Product Name
Unit Size
A0084 A1493 B0414 B0044 B0107 B0237 B1683 B1689 B0416 B1297 A0208 A5160
25g 25ml 25g 25g
B1684 B1685 B1384 B0444 B0447 B3358 C0596 C0050 C0172 C1180 C0329 D1306 D2003 D1630 D1016 I0453
Acetylcholine Chloride (3-Acrylamidopropyl)trimethylammonium Chloride (74-76% in Water) (stabilized with MEHQ) Benzalkonium Chloride (50% in Water) Benzethonium Chloride Benzoylcholine Chloride Benzylcetyldimethylammonium Chloride Hydrate N-Benzylcinchonidinium Chloride [Chiral Phase-Transfer Catalyst] N-Benzylcinchoninium Chloride [Chiral Phase-Transfer Catalyst] Benzyldimethylphenylammonium Chloride Benzyldimethylstearylammonium Chloride Hydrate Benzyldimethyltetradecylammonium Chloride Hydrate Benzyldimethyltetradecylammonium Chloride Hydrate [Ion association reagent for extraction
25g
25g 25g
photometric analysis and sensitizer in photometric determination of metals] N-Benzylquinidinium Chloride [Chiral Phase-Transfer Catalyst] N-Benzylquininium Chloride [Chiral Phase-Transfer Catalyst]
Benzyltributylammonium Chloride Benzyltriethylammonium Chloride Benzyltrimethylammonium Chloride 1-Butyl-1-methylpyrrolidinium Chloride Carbamylcholine Chloride DL-Carnitine Hydrochloride Chlorocholine Chloride (3-Chloro-2-hydroxypropyl)trimethylammonium Chloride (ca. 50% in Water) Choline Chloride Decyltrimethylammonium Chloride Diallyldimethylammonium Chloride (60% in Water) Dimethyldistearylammonium Chloride Dodecyltrimethylammonium Chloride Dodecyltrimethylammonium Chloride [Reagent for Ion-Pair Chromatography]
25g 25g 25g 5g 10g 25g 25g 25ml 25g 25ml 25g 25g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500g 500ml 500g 500g 25g 500g 10g 5g 25g 500g 500g 5g 5g 5g 500g 500g 500g 25g 25g 500g 500g 500ml 500g 25g 500ml 500g 500g 500g
337
Quaternary Ammonium Compounds
Product No. Product Name B0457 H0082 H0090 D0973 M0073 M0918 M0681 M1293 T1365 O0178 P0241 P0274 P0834 S0358 S0149 T1433 T0055 I0366 T0095 T0136 T2106 M0852 T1307 P0244 S0087 T0926 T2246 T0826
Girard's Reagent T Hexadecyltrimethylammonium Chloride Hexamethonium Chloride Dihydrate Lauroylcholine Chloride Methacholine Chloride Methacroylcholine Chloride (ca. 80% in Water) (stabilized with MEHQ) (2-Methoxyethoxymethyl)triethylammonium Chloride β-Methylcholine Chloride Methyltri-n-octylammonium Chloride n-Octyltrimethylammonium Chloride Phenyltriethylammonium Chloride Phosphocholine Chloride Calcium Salt Tetrahydrate Phosphocholine Chloride Sodium Salt Hydrate [for Cholinesterase Substrate] Stachydrine Hydrochloride Succinylcholine Chloride Dihydrate Tetraamylammonium Chloride Tetrabutylammonium Chloride Tetrabutylammonium Chloride [Reagent for Ion-Pair Chromatography] Tetraethylammonium Chloride Tetramethylammonium Chloride Tetrapropylammonium Chloride Triethylmethylammonium Chloride Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride Trimethylphenylammonium Chloride Trimethylstearylammonium Chloride Trimethyltetradecylammonium Chloride Trimethyl[3-(triethoxysilyl)propyl]ammonium Chloride Trioctylmethylammonium Chloride (R=C6-C10) [Phase-transfer Catalyst]
Unit Size 25g 25g 25g 25g 25g
25g
1g 5g 5g 5g 5g 25g 25g 25g 100mg 25g 25g 25g 5g 25g
500g 500g 500g 1g 500g 500g 5g 25g 500g 25g 25g 25g 5g 10mg 25g 25g 25g 25g 500g 500g 25g 500g 1g 500g 500g 500g 25g 500g
Bromides Product No. Product Name A0083 B0106 B1217 B0443 B2980 B0577 B2754 B3424 C0328 D1314 D3269 D1467 D2363 D1974 D2355 D1975 D2754 D2354 D1468 D0721 F0286 F0166 H0081 H0481 H0989 H0534 H0448 M0072 N0358 O0163 P0243 S0231 T1432 T0054
338
Acetylcholine Bromide Benzoylcholine Bromide Benzyltributylammonium Bromide Benzyltriethylammonium Bromide Benzyltrimethylammonium Bromide Bromocholine Bromide 1,1'-(Butane-1,4-diyl)bis[4-aza-1-azoniabicyclo[2.2.2]octane] Dibromide 1-Butyl-1-methylpiperidinium Bromide Choline Bromide Decamethonium Bromide 1,1'-(Decane-1,10-diyl)bis[4-aza-1-azoniabicyclo[2.2.2]octane] Dibromide Decyltrimethylammonium Bromide Didecyldimethylammonium Bromide Dilauryldimethylammonium Bromide Dimethyldimyristylammonium Bromide Dimethyldioctadecylammonium Bromide Dimethyldioctylammonium Bromide Dimethyldipalmitylammonium Bromide Dodecyltrimethylammonium Bromide Ethylhexadecyldimethylammonium Bromide (Ferrocenylmethyl)dodecyldimethylammonium Bromide (Ferrocenylmethyl)trimethylammonium Bromide Hexadecyltrimethylammonium Bromide Hexamethonium Bromide Hexyldimethyloctylammonium Bromide Hexyltrimethylammonium Bromide Homatropine Methyl Bromide Methacholine Bromide Neostigmine Bromide n-Octyltrimethylammonium Bromide Phenyltrimethylammonium Bromide Scopolamine Methyl Bromide Tetraamylammonium Bromide Tetrabutylammonium Bromide
Unit Size 25g 25g 25g 25g
5g 25g 5g 25g 25g 25g 25g 5g 25g 25g 25g 1g 25g 25g 5g 25g 5g 5g 25g 25g 5g 25g
25g 500g 500g 500g 250g 25g 1g 25g 500g 25g 1g 500g 5g 500g 500g 250g 25g 500g 500g 500g 5g 5g 500g 500g 25g 500g 25g 25g 25g 500g 500g 1g 25g 500g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Quaternary Ammonium Compounds
Product No. Product Name I0365 T1142 T0906 T0094 T1602 T1599 T0135 T1603 T0694 T1036 S0364 T0494 V0063
Unit Size
Tetrabutylammonium Bromide [Reagent for Ion-Pair Chromatography] Tetra(decyl)ammonium Bromide Tetradecyltrimethylammonium Bromide Tetraethylammonium Bromide Tetraheptylammonium Bromide Tetrahexylammonium Bromide Tetramethylammonium Bromide Tetra-n-octylammonium Bromide Tetrapropylammonium Bromide 3-(Trifluoromethyl)phenyltrimethylammonium Bromide Trimethylstearylammonium Bromide Trimethylvinylammonium Bromide Valethamate Bromide
25g 25g 25g 5g 25g 10g 25g
1g
500g 25g 500g 500g 25g 25g 500g 25g 500g 25g 25g 10g 25g
Iodides Product No. Product Name A0085 A0116 B0108 B0307 B0446 B0772 B0775 D1315 D1343 E0190 E0191 F0167 H0407 M0598 C0037 P0242 T1011 T0057 T0097 T1396 T1010 T0139 T1155 T0172 T1014 P0246 T2625
Acetylcholine Iodide Acetylthiocholine Iodide Benzoylcholine Iodide Benzoylthiocholine Iodide Benzyltriethylammonium Iodide Butyrylcholine Iodide Butyrylthiocholine Iodide Decamethonium Iodide 1,1-Dimethyl-4-phenylpiperazinium Iodide Ethyltrimethylammonium Iodide Ethyltripropylammonium Iodide (Ferrocenylmethyl)trimethylammonium Iodide (2-Hydroxyethyl)triethylammonium Iodide β-Methylcholine Iodide O-β-Naphthyloxycarbonylcholine Iodide [for Determination of Serum Cholinesterase] Phenyltriethylammonium Iodide Tetraamylammonium Iodide Tetrabutylammonium Iodide Tetraethylammonium Iodide Tetraheptylammonium Iodide Tetrahexylammonium Iodide Tetramethylammonium Iodide Tetra-n-octylammonium Iodide Tetrapropylammonium Iodide 3-(Trifluoromethyl)phenyltrimethylammonium Iodide Trimethylphenylammonium Iodide Trimethyl[2-[(trimethylsilyl)methyl]benzyl]ammonium Iodide
Unit Size 1g 1g
5g 1g 5g 5g 1g
5g 25g 25g
25g
5g 100g 25g 25g
25g 25g 25g 25g 25g 25g 25g 25g 5g 25g 25g 5g 10g 25g 100mg 25g 25g 500g 500g 25g 25g 500g 5g 500g 25g 500g 5g
Hydroxides Product No. Product Name B0445 B0448 B1071 B0378 B1070 B0428 C0326 H0083 H0974 S0070 T0056 T1948 T0717 T0041 T1685 T0955
Benzyltriethylammonium Hydroxide (10% in Water) Benzyltrimethylammonium Hydroxide (40% in Methanol) Benzyltrimethylammonium Hydroxide (40% in Water) Benzyltrimethylammonium Hydroxide (40% in Water) Benzyltrimethylammonium Hydroxide (10% in Water) Benzyltrimethylammonium Hydroxide (10% in Water) Choline (48-50% in Water) Hexadecyltrimethylammonium Hydroxide (25% in Methanol) Hexadecyltrimethylammonium Hydroxide (10% in Water) Sphingomyelin from Bovine Brain Tetrabutylammonium Hydroxide (10% in Isopropyl Alcohol) Tetrabutylammonium Hydroxide (37% in Methanol) Tetrabutylammonium Hydroxide (10% in Methanol) Tetrabutylammonium Hydroxide (10% in Methanol) [for non-aqueous titration] Tetrabutylammonium Hydroxide (40% in Water) Tetrabutylammonium Hydroxide (10% in Water)
Unit Size 25ml 500ml 500ml 25ml 25ml 500ml 25ml 25g 500g 25ml 500ml 25ml 500ml Price on request 25g 25ml 500ml 25ml 500ml 25ml 500ml 25g 500g 25ml 500ml 25ml 25ml
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
339
Quaternary Ammonium Compounds
Product No. Product Name T0216 I0364 T2589 T0096 I0363 T1134 T0676 T1201 T1460 T0138 T1404 T1565 T1020 T0171 T0964 T0961
Tetrabutylammonium Hydroxide (10% in Water) Tetrabutylammonium Hydroxide (10% in Water) [Reagent for Ion-Pair Chromatography] Tetraethylammonium Hydroxide (35% in Water) Tetraethylammonium Hydroxide (10% in Water) Tetraethylammonium Hydroxide (10% in Water) [Reagent for Ion-Pair Chromatography] Tetrahexylammonium Hydroxide (10% in Methanol) Tetramethylammonium Hydroxide (10% in Methanol) Tetramethylammonium Hydroxide (10% in Methanol) [for Photoresist Research] Tetramethylammonium Hydroxide (ca. 25% in Water) Tetramethylammonium Hydroxide (10% in Water) Tetramethylammonium Hydroxide Pentahydrate Tetrapropylammonium Hydroxide (ca. 40% in Water) Tetrapropylammonium Hydroxide (20-25% in Water) Tetrapropylammonium Hydroxide (10% in Water) Tetrapropylammonium Hydroxide (10% in Water) 3-(Trifluoromethyl)phenyltrimethylammonium Hydroxide (5% in Methanol)
Unit Size 25ml 25ml
25ml
25g
25ml 25ml 100g 25ml 25ml 25ml
[for Transesterification of Glyceride]
P0878 P0245 T2192
Trimethylphenylammonium Hydroxide (20-25% in Methanol) Trimethylphenylammonium Hydroxide (20-25% in Methanol) [for On-Column Methylation] Tris(2-hydroxyethyl)methylammonium Hydroxide (45-50% in Water)
25ml
25g 25ml 500ml 500ml 25ml 5g 500ml 25ml 500ml 500ml 500g 25g 500ml 500ml 500ml 25ml 500ml 25ml 25g
(stabilized with MEHQ)
Others Product No. Product Name A0998 A2274 B3128 B1604 B1543 T1382 B0455 B0458 B1123 B1466 B2851 C0049 C1578 C0553 C0793
Acetylcholine Perchlorate Amyltriethylammonium Bis(trifluoromethanesulfonyl)imide Benzyltriethylammonium Borohydride Benzyltrimethylammonium Dichloroiodate Benzyltrimethylammonium Tetrachloroiodate [Chlorinating Reagent] Benzyltrimethylammonium Tribromide [Brominating Reagent] Betaine Anhydrous Betaine Hydrochloride Bis(tetrabutylammonium) Dichromate [Oxidizing Reagent] Bis(tetrabutylammonium) Tetracyanodiphenoquinodimethanide 1-Butyl-1-methylpyrrolidinium Bis(trifluoromethanesulfonyl)imide L-Carnitine 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate Choline Bitartrate 1-Cyclohexyl-3-(2-morpholinoethyl)carbodiimide Metho-p-toluenesulfonate
C1966 D2124 D2332 F0358 H1283
Cyclohexyltrimethylammonium Bis(trifluoromethanesulfonyl)imide Denatonium Benzoate Dodecyldimethyl(3-sulfopropyl)ammonium Hydroxide Inner Salt N-Fluoro-N '-(chloromethyl)triethylenediamine Bis(tetrafluoroborate) Hexadecyldimethyl(3-sulfopropyl)ammonium Hydroxide Inner Salt [for Biochemical
H0733 H0735 H0734 M2005 M1279 M2098 M1660 M1457 N0447 O0261 P0517 S0230 T2694 T0920 T1295 T0917 T1270 T1261 T1189 T1269
Hexadecyltrimethylammonium Hexafluorophosphate Hexadecyltrimethylammonium Perchlorate Hexadecyltrimethylammonium Tetrafluoroborate 2-(Methacryloyloxy)ethyl 2-(Trimethylammonio)ethyl Phosphate (Methoxycarbonylsulfamoyl)triethylammonium Hydroxide Inner Salt 1-Methyl-1-propylpyrrolidinium Bis(trifluoromethanesulfonyl)imide Methyltri-n-octylammonium Bis(trifluoromethanesulfonyl)imide Methyltri-n-octylammonium Hydrogen Sulfate Neostigmine Methyl Sulfate Octadecyldimethyl(3-sulfopropyl)ammonium Hydroxide Inner Salt Propionylcholine p-Toluenesulfonate Scopolamine Methyl Nitrate Tetrabutylammonium Acetate Tetrabutylammonium Azide Tetrabutylammonium Bifluoride Tetrabutylammonium Borohydride [Reducing Reagent] Tetrabutylammonium Bromodiiodide Tetrabutylammonium Dibromoaurate Tetrabutylammonium Dibromochloride Tetrabutylammonium Dibromoiodide
Unit Size 5g 5g 5g 25g 25g
5g 5g 1g 25g 5g
[for Peptide Synthesis]
5g 25g 5g
Research]
340
1g
5g 1g 1g 1g 1g 5g 5g 1g 5g 25g 1g 1g 25g 5g 5g 5g
1g
10g 5g 25g 25g 5g 25g 500g 500g 10g 100mg 25g 25g 5g 500g 25g 5g 25g 250g 25g 25g 25g 5g 5g 5g 25g 25g 5g 5g 25g 250g 25g 5g 500g 25g 25g 25g 1g 1g 25g 10g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Quaternary Ammonium Compounds
Product No. Product Name T1273 T1186 T1909 T1592 T1635 T1357 T1279 T0835 I0368 T2669 T0836 T1803 I0367 T1276 T0914 T2648 T1480 T1278 T1284 T1568 T1271 T2653
Tetrabutylammonium Dichloroaurate Tetrabutylammonium Dichlorobromide Tetrabutylammonium Difluorotriphenylsilicate Tetrabutylammonium Difluorotriphenylstannate Tetrabutylammonium Dihydrogen Trifluoride Tetrabutylammonium Diiodoaurate Tetrabutylammonium Hexafluorophosphate Tetrabutylammonium Hydrogen Sulfate Tetrabutylammonium Hydrogen Sulfate [Reagent for Ion-Pair Chromatography] Tetrabutylammonium p-Nitrophenoxide Tetrabutylammonium Perchlorate Tetrabutylammonium Perrhenate Tetrabutylammonium Phosphate (0.5mol/L in Water) [Reagent for Ion-Pair Chromatography] Tetrabutylammonium Salicylate Tetrabutylammonium Tetrafluoroborate Tetrabutylammonium Tetrafluoroborate Tetrabutylammonium Tetraphenylborate Tetrabutylammonium Thiocyanate Tetrabutylammonium Tribromide Tetrabutylammonium Trifluoromethanesulfonate Tetrabutylammonium Triiodide Tetradecyldimethyl(3-sulfopropyl)ammonium Hydroxide Inner Salt [for Biochemical
T0837 T0839 T0983 T0937 T1745 T1048 T1397 T0852 T1296 T0840 T0841 T1240 T0842 T0843 T1553 T1559 T2198 P0928
Tetraethylammonium Borohydride Tetraethylammonium Perchlorate Tetraethylammonium Tetrafluoroborate Tetraethylammonium p-Toluenesulfonate Tetraethylammonium Trifluoromethanesulfonate Tetramethylammonium Acetate Tetramethylammonium Acetate (ca. 15% in Water) Tetramethylammonium Borohydride [Reducing Reagent] Tetramethylammonium Hexafluorophosphate Tetramethylammonium Hydrogen Sulfate Tetramethylammonium Perchlorate Tetramethylammonium Sulfate Tetramethylammonium Tetrafluoroborate Tetramethylammonium p-Toluenesulfonate Tetramethylammonium Triacetoxyborohydride Tetrapropylammonium Perruthenate Triethylmethylammonium Tetrafluoroborate Trimethylphenylammonium Tribromide
Research]
Unit Size 5g 1g 5g 100mg 25g 25g 25g 5g 25g 1g 10ml 25g 1g 25g 25g 10g 1g 5g 5g
25g 5g
5g
5g 25g 5g 1g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
100mg 25g 25g 5g 25g 1g 250g 500g 100g 25g 500g 5g 100ml 25g 500g 25g 5g 250g 500g 25g 25g 25g 25g 25g 25g 500g 25g 25g 25g 25g 25g 25g 25g 25g 500g 25g 25g 5g 25g 500g
341
Imidazolium Compounds
Imidazolium Compounds
D3611
B3159
B2473
B2474
B3028
(CH3)2CH
CH3
N
N N (CH3)2CH
CH(CH3)2
B2475
Cl
N
N
(CH2)3CH3
N
(CF3SO2)2N
N
CH3
B2708
CH3
N I
D3621
CH3
N
(CH2)3CH3
D3711
(CH2)3CH3
B3542
CH3 BF4
CH3
N CF3SO3
CF3BF3
N
N
(CH2)3CH3
(CH2)3CH3
D3882
PF6
N
(CH2)3CH3
N
(CH2)3CH3
Cl
N
CH3
N
B2337 N
FeCl4
N
N (CH2)3CH3
Br
B2195
CH3
CH3
N
(CH2)3CH3
B2672
N
B2320
CH3
N
(CH2)3CH3
(CH2)3CH3
Lipase
CH3(CH2)15O(CH2CH2O)nSO3
B2194
N
CH3
N CH3 (CH2)3CH3
CH3
(CH2)3CH3
(CH2)3CH3
CH3
N
BF4
N PF6
N
CH3
B2193
CH3
CH3
N Cl
CH3
B2477
N
CH3
N (CF3SO2)2N
CH(CH3)2
D3850
D3623
CH3 N
N
N
C CH3
N
N
CH3
N BF4
N Cl
N
BF4
N
N
BF4
CH3 C CH3
CH
CH3
D3446
D3341 CH3
D3240
CH3
CH3 CH3 BF4
CH3
E0753
CH3
N
N
CH3
N
CH3
N CH3
D3903
CH
CH3
Cl
Cl
N CH3
CH3 CH3O
N
CH3O
N
O P O
CH2CH2CH3
CH3
N
I CH3
N
CH3
CH3
(CF3SO2)2N N
CH3
CH2CH3
CH3
E0599
E0543
N
CH3
N
(CF3SO2)2N
N
N Br
N
CH2CH3
PF6
Cl
N
CH2CH3
HSO4
(NC)2N
N
N
CH2CH3
N I
CH3 CH3CH2OSO3
N
E0683
CH3
N
N
CH2CH3
E0755
CH3
N
CH3
CH2CH3
E0556
CH3
N
N
CH2CH3
E0754
E0650
CH3
N
CH2CH3
E0493
E0680
CH3
N
CH2CH3
342
E0490
CH3
N CH2CH3
CH3SO3
N N
CH3 CH3(OCH2CH2)2OSO3
CH2CH3
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Imidazolium Compounds
E0706
E0496
N
E0651
CH3
N
FeCl4
N
N
N
Br
N
CH2CH3
M2063
N
N Cl
(CH2)7CH3
CF3SO3
CH2CH3
M1904
N
PF6
N
N
CH3
N
BF4
Br
(CH2)7CH3
CH3
N
PF6
(CH2)7CH3
N N
CH3 I
CH2CH2CH3
Unit Size
1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride 1-Butyl-2,3-dimethylimidazolium Bis(trifluoromethanesulfonyl)imide (This product is only available for selling domestically in Japan)
B2473 B2474 B3028
CH3
N
(CH2)5CH3
Product No. Product Name D3611 B3159
CF3BF3
N
CH2CH3
CH3
(CH2)5CH3
CH3
M1440
CH3
N
N
Cl
N
M2062
CH3
N
H1099
CH3
(CH2)5CH3
CH3
N
H1098
CH3
(CH2)5CH3
N
N
H1097
N
CH3
BF4
CH2CH3
H1227
E0836
SO3
CH3
N
CH2CH3
E0494
B2475 B2477
1-Butyl-2,3-dimethylimidazolium Chloride 1-Butyl-2,3-dimethylimidazolium Hexafluorophosphate 1-Butyl-2,3-dimethylimidazolium Polyethylene Glycol Hexadecyl Ether Sulfate coated Lipase (This product is only available for selling domestically in Japan) 1-Butyl-2,3-dimethylimidazolium Tetrafluoroborate 1-Butyl-3-methylimidazolium Bis(trifluoromethanesulfonyl)imide (This product is only
B2193 B2194 B2320 B2708 B2672 B2195 B2337 B3542 D3621 D3711 D3882
1-Butyl-3-methylimidazolium Bromide 1-Butyl-3-methylimidazolium Chloride 1-Butyl-3-methylimidazolium Hexafluorophosphate 1-Butyl-3-methylimidazolium Iodide 1-Butyl-3-methylimidazolium Tetrachloroferrate 1-Butyl-3-methylimidazolium Tetrafluoroborate 1-Butyl-3-methylimidazolium Trifluoromethanesulfonate 1-Butyl-3-methylimidazolium Trifluoro(trifluoromethyl)borate 1,3-Di(1-adamantyl)imidazolium Tetrafluoroborate 1,3-Di-tert-butylimidazolium Tetrafluoroborate 1,3-Dicyclohexylimidazolium Chloride (This product is only available for selling domestically
D3850 D3623 D3446 D3341 D3240 D3903 E0753
1,3-Dicyclohexylimidazolium Tetrafluoroborate 1,3-Diisopropylimidazolium Tetrafluoroborate 1,3-Dimesitylimidazolium Chloride 1,3-Dimethylimidazolium Chloride 1,3-Dimethylimidazolium Dimethyl Phosphate 1,2-Dimethyl-3-propylimidazolium Iodide 1-Ethyl-2,3-dimethylimidazolium Bis(trifluoromethanesulfonyl)imide (This product is
E0599
1-Ethyl-3-methylimidazolium Bis(trifluoromethanesulfonyl)imide (This product is only
5g
only available for selling domestically in Japan) available for selling domestically in Japan)
E0706
1-Ethyl-3-methylimidazolium Tetrachloroferrate
available for selling domestically in Japan)
25g 25g 25g
5g
1g 25g
25g 5g 5g 5g 5g 5g
1g 1g
in Japan)
1-Ethyl-3-methylimidazolium Bromide 1-Ethyl-3-methylimidazolium Chloride [for Molten Salt] 1-Ethyl-3-methylimidazolium Dicyanamide 1-Ethyl-3-methylimidazolium Ethyl Sulfate 1-Ethyl-3-methylimidazolium Hexafluorophosphate [for Molten Salt] 1-Ethyl-3-methylimidazolium Hydrogen Sulfate 1-Ethyl-3-methylimidazolium Iodide 1-Ethyl-3-methylimidazolium Methanesulfonate 1-Ethyl-3-methylimidazolium 2-(2-Methoxyethoxy)ethyl Sulfate (This product is only
5g
5g 5g 5g
5g
available for selling domestically in Japan)
E0543 E0490 E0680 E0650 E0493 E0754 E0556 E0755 E0683
500mg
5g
25g 5g 100g 25g 25g 25g 25g 25g 5g 1g 5g
1g 5g 5g 5g
5g 5g 1g 5g 25g 25g 25g
5g
25g
5g 5g 25g 1g 5g 5g 5g 5g 5g
25g 25g 250g 5g 25g 25g 25g 25g 25g
5g
25g 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
343
Imidazolium Compounds
Product No. Product Name
344
Unit Size
E0496 E0651
1-Ethyl-3-methylimidazolium Tetrafluoroborate [for Molten Salt] 1-Ethyl-3-methylimidazolium p-Toluenesulfonate (This product is only available for selling
5g
25g
domestically in Japan)
E0494 E0836 H1227 H1097 H1098 H1099 M1904 M2062 M2063 M1440
1-Ethyl-3-methylimidazolium Trifluoromethanesulfonate 1-Ethyl-3-methylimidazolium Trifluoro(trifluoromethyl)borate 1-Hexyl-3-methylimidazolium Bromide 1-Hexyl-3-methylimidazolium Chloride 1-Hexyl-3-methylimidazolium Hexafluorophosphate 1-Hexyl-3-methylimidazolium Tetrafluoroborate 1-Methyl-3-n-octylimidazolium Bromide 1-Methyl-3-n-octylimidazolium Chloride 1-Methyl-3-n-octylimidazolium Hexafluorophosphate 1-Methyl-3-propylimidazolium Iodide
5g 5g
25g 25g 5g 25g 25g 25g 25g 25g 25g 25g 25g
5g 5g 5g 5g 5g 5g 5g 5g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Pyridinium Compounds
Pyridinium Compounds
A0828
A0629
B3361
B2280
B2279
H2C
CH2
N
Cl
N
I
N
O
N
CH2
C CH3
NH2
N
CH2
N
N
OCH2
CH3
2Br
2PF6
CF3SO3 N
B1518
H2C
B2358
B1036
N
B1171
N
N
B0653 Br
NO2 O2N
N
N
NO2
CH3
N Br N
2Cl
CH3 PF6
N
CH3 CH3
B3104 CH3
Br
B2701 CH3
B1329
PF6
Cl N
(CH2)3CH3
(CH2)3CH3
CH3
Cl
N
N
Cl N H
B3426 CH3
Br
(CH2)3CH3
Br N H
B3425 CH3
B1743
BF4
Br
CH2CH3
B2700
N
Br
CH3 CH3
O2N
N
(CH2)3CH3
B2196
B3232
(CH2)3CH3
C1631 O C NH2
Br Cl
N
N
PF6
N
BF4
N
(CH2)3CH3
(CH2)3CH3
(CH2)3CH3
Cl
(CH2)3CH3
N (CH2)15CH3
A0829
M0375
C0822
C0825
C0805
O Cl N CH2
Cl
O
N
C NH2
C0903
Cl
N +
CH2CN
N
Cl
F0342
CH2 N
D3812
N CH2
4PF6
+ N
BF4
CN
D2137 N +
CH3
N
(CH2)15CH3
N
CH3
. H2O
CH3
Cl + N
N
Cl
Cl
CH3
C1749
N
C2348
Cl N
C0848
N H
A5161
I
CH3
Cl
Cl
N H
C0281 SO3
Cl
CH2Cl
N H
CH3
C0906
N
CH2Cl
CH2Cl
C NH2
Cl 2Cl
. xH2O
N F
Cl
CF3SO3
N
N
F
F 2BF4
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
345
Pyridinium Compounds
D1593
D2025
D1850
D1787
D2915
N(CH3)2 N(CH3)2 CH3(CH2)6 N
Cl
N (CH2)6CH3
HO
2Br
N H
CH3
Cl
OH
N
CH3
CH2
C CH3
Br3
N
CH3
N H
Cl
CH3
D2527
D0713 D3685
D1771
D1854
CH2CH2SO3
CH3 N
N CH3
CH3(CH2)7 N
N
CH3
C N CH3
N H
E0682
N
N
(CH2)7CH3
N
2Br
CH3
2Cl
CH3
O CH3
D0995
D2165
SO3
2Cl
. xH2O
N C
E0362
E0756
E0681
O C OCH3
CH2OH Cl
N
(CH2)11CH3
CH3CH2OSO3
N
I
(CF3SO2)2N
N
N
CH2CH3
CH3
CH3
CH3CH2OSO3
N
CH2CH3
CH2CH3
CH2CH3
E0171
E0544
F0344
F0225
F0334 SO3
Br
N
F0343
Cl
N
CH2CH3
Cl
N
CH2CH3
Cl
BF4
N
F
F0327
F0346
BF4
G0030
BF4 CH3
F
F
H0967
N
CF3SO3 CH3
CH3
N
H0078
O
A5400 O C Cl
. xH2O
Br
Cl
Cl
. xH2O
N (CH2)15CH3
Me N
. H2O
N
Cl
(CH2)15CH3
M0819
M1397
A5401
CH NOH Cl
N
CH3
CH2 N
Cl
N N
O0192 CH
CHCH CH
Br
Br
N
P1407
(CH2)17CH3
P1405
N
N
Br
N
(CH2)17CH3
P0797
CH
NEt2
CH3
P1054
NEt2
I
O0193 CH
O2N
N N
N
(CH2)15CH3
N
CH2 C NHNH2
CH3
I0144
CH3
N
Cl
N
F
F
H0162
F
CH3
CH3
CF3SO3
N
B2F7
N
N
F0328 CH3
N
F
CH3
P0199
N
O
N
C NH N
Br
(CH2)9C C C C(CH2)11CH3
N
O
Br 2PF6
CH2 C N
346
2Br
N H N
N
Cl
N
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Pyridinium Compounds
P0422
P0619
O
P1666
P1637
Br
O
Cl
C OH
N H
P1393
N H
P0825
C Cl
Cl
Cl
N
CH2CH2CH3
P0930
Cl N H
N H
P0931
P1088
P0941 SO3
2
Br3 N H
P0999
Cr2O7
ClCrO3
N H
N H
P0942
FCrO3
N H
2
P1627
N H
P1339
P0560 O
SO3
O C N
. (HF)x
CF3SO3 N H
N H
N
N
P0561
P1076
P0639
OH
. 2HCl N
CH3
S0391
O
OH O
Cl N H
HOCH2
Br
P0565
CH2OH HOCH2
CH2NH2
CH3 CH3
CH3
CH3
NO2
N
CH3
CH2
CH2
. HCl
C OH
C OH
N
Cl
Cl
N H
. HCl . xH2O
N (CH2)3SO3
N
A5014
T2602 CH3 N
CH3 N
NH N N HN
N
4
T1122 O
CH3
SO3
4
SO3
CH3
O
CF3CO2
N CH3 CH3
N CH3
T1429 CH3
N
N
C CF3
CH3
. HCl
CH3
N H
CH3 CH3
O
Product No. Product Name
Unit Size
A0828 A0629 B3361
1-Acetonylpyridinium Chloride 1-Aminopyridinium Iodide 2-Benzyloxy-1-methylpyridinium Trifluoromethanesulfonate
5g 5g
25g 25g
(This product is only available for selling domestically in Japan)
1g
5g
B2280
1,1'-[Biphenyl-4,4'-diylbis(methylene)]bis(4,4'-bipyridinium) Bis(hexafluorophosphate) 1,1'-[Biphenyl-4,4'-diylbis(methylene)]bis(4,4'-bipyridinium) Dibromide 1,1'-Bis(2,4-dinitrophenyl)-4,4'-bipyridinium Dichloride Bis(2,4,6-trimethylpyridine)bromonium Hexafluorophosphate 2-Bromo-1-ethylpyridinium Tetrafluoroborate 4-Bromopyridine Hydrobromide 4-Bromopyridine Hydrochloride 1-Butyl-3-methylpyridinium Bromide 1-Butyl-4-methylpyridinium Bromide 1-Butyl-3-methylpyridinium Chloride 1-Butyl-4-methylpyridinium Chloride 1-Butyl-4-methylpyridinium Hexafluorophosphate 1-Butylpyridinium Bromide 1-Butylpyridinium Chloride 1-Butylpyridinium Hexafluorophosphate 1-Butylpyridinium Tetrafluoroborate 4-Carbamoyl-1-hexadecylpyridinium Chloride 1-(Carbamoylmethyl)pyridinium Chloride 3-Carbamyl-1-methylpyridinium Chloride
B2279 B1518 B2358 B1036 B1171 B0653 B3104 B2700 B3425 B3426 B2701 B1743 B1329 B2196 B3232 C1631 A0829 M0375
100mg 500mg 100mg 1g 5g 25g 1g 5g 5g 25g 5g 25g 5g 25g 5g 25g 5g 25g 1g 5g 5g 25g 5g 25g 5g 25g 10g 25g 5g 25g 5g 25g 5g 5g 25g 5g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
347
Pyridinium Compounds
Product No. Product Name C0822 C0825 C0805 C0903 C0906 C0281 A5161
Unit Size
2-(Chloromethyl)pyridine Hydrochloride 3-(Chloromethyl)pyridine Hydrochloride 4-(Chloromethyl)pyridine Hydrochloride 2-Chloro-1-methylpyridinium Iodide 2-Chloro-1-methylpyridinium p-Toluenesulfonate 4-Chloropyridine Hydrochloride CPC Monohydrate (=Cetylpyridinium Chloride Monohydrate) [Ion association reagent for
25g 25g 25g 25g 25g
extraction photometric analysis and sensitizer in photometric determination of metals]
C2348 C0848 C1749 D2137 F0342 D3812 D1593 D2025 D1850 D1787 D2915
1-Cyano-4-(dimethylamino)pyridinium Tetrafluoroborate 1-(Cyanomethyl)pyridinium Chloride Cyclobis(paraquat-1,4-phenylene) Tetrakis(hexafluorophosphate) 1,1'-Dibenzyl-4,4'-bipyridinium Dichloride Hydrate 2,6-Dichloro-1-fluoropyridinium Trifluoromethanesulfonate [Fluorinating Reagent] 1,1'-Difluoro-2,2'-bipyridinium Bis(tetrafluoroborate) 1,1'-Diheptyl-4,4'-bipyridinium Dibromide [for Electrochromic Material] 2,6-Dihydroxypyridine Hydrochloride 4-Dimethylamino-1-neopentylpyridinium Chloride 4-Dimethylaminopyridinium Bromide Perbromide 4-(Dimethylamino)-1-(triphenylmethyl)pyridinium Chloride
D0713 D3685 D2527 D1771 D1854 D2165 D0995 E0682 E0362 E0756
1,1'-Dimethyl-4,4'-bipyridinium Dichloride Hydrate 1,1'-Dimethyl-4,4'-bipyridinium Dichloride 1-(Dimethylcarbamoyl)-4-(2-sulfoethyl)pyridinium Hydroxide Inner Salt 2,6-Dimethylpyridinium p-Toluenesulfonate 1,1'-Di-n-octyl-4,4'-bipyridinium Dibromide 1,1'-Diphenyl-4,4'-bipyridinium Dichloride 1-Dodecylpyridinium Chloride 1-Ethyl-3-(hydroxymethyl)pyridinium Ethyl Sulfate 1-Ethyl-4-(methoxycarbonyl)pyridinium Iodide 1-Ethyl-3-methylpyridinium Bis(trifluoromethanesulfonyl)imide (This product is only
1g
5g 5g
5g 5g
(contains 5% Dichloromethane at maximum)
1g 1g
25g 1g
1-Ethyl-3-methylpyridinium Ethyl Sulfate 1-Ethylpyridinium Bromide 1-Ethylpyridinium Chloride 1-Fluoro-2,6-dichloropyridinium Tetrafluoroborate [Fluorinating Reagent] 2-Fluoro-1-methylpyridinium p-Toluenesulfonate [Fluorinating Reagent] 1-Fluoropyridinium Pyridine Heptafluorodiborate [Fluorinating Reagent] 1-Fluoropyridinium Tetrafluoroborate [Fluorinating Reagent] 1-Fluoropyridinium Trifluoromethanesulfonate [Fluorinating Reagent] 1-Fluoro-2,4,6-trimethylpyridinium Tetrafluoroborate [Fluorinating Reagent] 1-Fluoro-2,4,6-trimethylpyridinium Trifluoromethanesulfonate [Fluorinating Reagent] Girard's Reagent P 1-Hexadecyl-4-methylpyridinium Chloride Hydrate Hexadecylpyridinium Bromide Hydrate Hexadecylpyridinium Chloride Monohydrate Isonicotinoyl Chloride Hydrochloride MDEPAP [=1-Methyl-4-(4-diethylaminophenylazo)pyridinium Iodide]
M0819 M1397 A5401
1-Methylpyridinium-2-aldoxime Chloride 1-Methylpyridinium Chloride NDEPAP [=1-(4-Nitrobenzyl)-4-(4-diethylaminophenylazo)pyridinium Bromide]
5g
1g 25g 25g
5g 5g 5g 5g 5g 5g
[Extraction-spectrophotometric reagent for anionic surfactants]
O0193 O0192 P1054 P0797 P1407 P1405 P0199 P0422 P0619 P1393 P1666 P1637 P0825 P0930 P0931 P1088 P0941
348
1-Octadecyl-4-(4-phenyl-1,3-butadienyl)pyridinium Bromide N-Octadecyl-4-stilbazole Bromide 1-(10,12-Pentacosadiynyl)pyridinium Bromide 1-Phenacylpyridinium Bromide 1,1'-[1,4-Phenylenebis(methylene)]bis(4,4'-bipyridinium) Bis(hexafluorophosphate) 1,1'-[1,4-Phenylenebis(methylene)]bis(4,4'-bipyridinium) Dibromide N-Phenylnicotinamide Hydrochloride Picolinic Acid Hydrochloride Picolinoyl Chloride Hydrochloride 1-Propylpyridinium Chloride Pyridine Hydrobromide Pyridine Hydrochloride Pyridinium Bromide Perbromide Pyridinium Chlorochromate Pyridinium Dichromate Pyridinium Fluorochromate Pyridinium 3-Nitrobenzenesulfonate
100mg
5g 100mg 100mg
5g
25g
5g 10g 5g 25g 25g 5g 1g 500g 5g 5g
25g 25g 25g
5g
[Extraction-spectrophotometric reagent for anionic surfactants]
5g 100mg 5g 100mg 25g 25g 1g 5g 25g 1g 25g
5g 25g 25g 25g 25g 25g 5g 25g 25g 5g 25g 25g 5g 500g 500g 250g
available for selling domestically in Japan)
E0681 E0171 E0544 F0344 F0225 F0334 F0343 F0327 F0346 F0328 G0030 H0967 H0162 H0078 I0144 A5400
250g 100g 250g 500g 25g 250g
25g 25g 25g 100g 25g 5g
1g 1g 1g 100mg 25g 1g 1g 10g 25g 25g 5g 250g 500g 500g 500g 500g 5g 25g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Pyridinium Compounds
Product No. Product Name P0999 P0942 P1627 P1339 P0560 P0561 P1076 P0639 P0565 S0391 A5014
Pyridinium Poly(hydrogenfluoride) [Fluorinating Reagent] Pyridinium p-Toluenesulfonate Pyridinium Trifluoromethanesulfonate Pyridostigmine Bromide Pyridoxamine Dihydrochloride Monohydrate Pyridoxine Hydrochloride 2-Pyridylacetic Acid Hydrochloride 3-Pyridylacetic Acid Hydrochloride 1-(4-Pyridyl)pyridinium Chloride Hydrochloride Hydrate 1-(3-Sulfopropyl)pyridinium Hydroxide Inner Salt TMPyP [=α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate] [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]
T2602 T1429 T1122
Unit Size 25g 25g 5g 5g 1g 25g 5g 10g 25g 100mg
1-(Trifluoroacetyl)-4-(dimethylamino)pyridinium Trifluoroacetate Trigonelline Hydrochloride 2,4,6-Trimethylpyridinium p-Toluenesulfonate
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
100g 500g 25g 25g 5g 500g 25g 25g 25g 250g 1g 5g 5g 25g
349
Phosphonium Compounds
Phosphonium Compounds
A1305
A1007
A1012
A0862
B1774 N
O P CH2
N
N P CH2CH CH2
P CH2CH CH2
C CH3
B1651
P
(CH2)4CH3
Cl
Br
Cl
B2025
B0824
O
PF6 N P N N
Br
B1206
B1208
N N
N
P CH2
PF6
P CH2CH2CH2Br
Br
Br
Cl
Br
B2286
P CH2Br
P CH2
OP[N(CH3)2]3
B0970
C1061
C1635
C1759 Cl O
O P CH2CH CHCH2
P
P
P
(CH2)3CH3
P
(CH2)4 C OH
(CH2)3 C OH
CH2
P
Br
Br
Br
2Cl
Cl
C1581
C1009
P CH2
C1286
Cl
P CH2Cl
Cl
C1739
P CH2CH
C1378
P
CH
CH2CN
P
Cl
Br
Br
Cl
D3330
D2907
D1654
D1655
D2056
Cl C(CH3)3 CH3
P CH2
B
P H
Cl
P CH2CH2N
C(CH3)3
Cl
D2164
O
O Br
Br
E0382
E0549
O
O P CH2
CH3
E0407
P CH2CH2
P CH2CH2
Br
E0421
O
O
CH3
Br
O
P CH2
Br
F0331
H0545
P CH2CH3
P CH2 C OCH2CH3
OCH2CH3
P+ CH2CH3 I -
Br
Br
H0540
H1240
I0552 HO
O P CH2
C H Cl
350
P
(CH2)6CH3 Br
P
(CH2)5CH3 Br
P CH2
P CH(CH3)2 I
Br
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Phosphonium Compounds
M1326
M0828
M1151
O P CH2
C OCH3
CH3
P CH2OCH3
Br
M0779
M0253
I
N P
P CH3
P CH3
Br
I
Cl
N0700
N0701
O0195
P1182
T2005 (CH2)3CH3
(CH3)2N P CH2
P
Cl
N(CH3)2
CH3(CH2)3 P O
(CH3)2N P O P N(CH3)2
CH2
NO2
(CH3)2N
Br
P CH2
N(CH3)2
(CH2)3CH3
(CH2)3CH3
C
N
2BF4
Br
N
T1416
T1124
S
S
S
S
S
S
S
S
S
T1649
(CH2)3CH3
Ni
S
CH3(CH2)3 P
T2006
(CH2)3CH3
Cl
CH3(CH2)3 P
(CH2)3CH3
(CH2)3CH3
(C4H9)4P
T2008
T2571
(CH2)3CH3
(CH2)3CH3
(CH2)3CH3 Br
CH3(CH2)3 P
T2007
(CH2)3CH3
(CH2)3CH3 PF6
CH3(CH2)3 P
(CH2)3CH3 OH
(CH2)3CH3
(CH2)3CH3
T1379
N
T1746
T1747
(CH2)3CH3 (CH2)3CH3 CH3(CH2)3 P
CH3(CH2)3 P
(CH2)3CH3 BF4
(CH2)3CH3
CH2CH3
(CH2)3CH3
CH2CH3
CH3CH2 P CH2CH3 Br
(CH2)3CH3
CH2CH3
CH3CH2 P CH2CH3 PF6
CH2CH3
CH3CH2 P CH2CH3 BF4 CH2CH3
CH2CH3
B(C6H5)4
T0607
T1089
CH2OH
T1650
CH2OH
HOCH2 P CH2OH
Cl
CH2OH
T1450
T1375
(CH2)7CH3
HOCH2 P CH2OH
CH2OH
T1069
SO42
CH3(CH2)7 P
(CH2)7CH3
Br
P
Br
P
Cl
(CH2)7CH3
2
T1329
T2603
C1442
T2718
CH3
(CH2)3CH3
P
P
I
B
CH3
B
P
CH3
CH3(CH2)3 P CH2CN Cl
O O
(CH2)3CH3
(CH2)3CH3 CH2 P
Br
(CH2)3CH3
(CH2)3CH3
CH3
D2912
H1047
T2564
T2680 (CH2)3CH3
(CH2)3CH3 (CH2)3CH3 CH3(CH2)3 P
(CH2)3CH3
(CH2)11CH3 Br
CH3(CH2)3 P
(CH2)3CH3
(CH2)15CH3 Br
CH3OCH2CH2 P
(CH2)3CH3
CH3
(CH2)3CH3
(CH2)3CH3
T2584
(CH2)7CH3
(CH2)3CH3
Br
(CH3)3C P H C(CH3)3
(CH2)3CH3
(CH2)3CH3 CH3(CH2)3 P
I
CH3
(CH2)3CH3
(CF3SO2)2N
T2585
T1458
C(CH3)3
C(CH3)3
(CH2)3CH3 CH3(CH2)3 P
T2258
P
(CH2)3CH3
(CF3SO2)2N
O0297
M1455
BF4
(CH3)3C P H C(CH3)3 (C6H5)4B
CH3
P H
BF4
P CH2OCH2CH2 Si CH3 CH3 Cl
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
351
Phosphonium Compounds
T1510
T1498
P1438
CH3 P CH2CH2 Si CH3
P1200
T1506
CH3 P CH2C C Si CH3
P
CH2C
CH Br
P CH2CH2CH3 Br
P
(CH2)13CH3
Br
CH3
CH3 Br
I
T1644
P CH CH2 Br
Product No. Product Name A1305 A1007 A1012 A0862 B1774
Acetonyltriphenylphosphonium Chloride Allyltriphenylphosphonium Bromide Allyltriphenylphosphonium Chloride Amyltriphenylphosphonium Bromide 1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate
B1651
1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate
B2025 B0824 B1206 B1208 B2286 B0970 C1061 C1635 C1759 C1581 C1009 C1286 C1739 C1378 D3330 D2907 D1654 D1655 D2056 D2164 E0421 E0407 E0382 E0549 F0331 H0545 H0540 H1240 I0552 M1326 M0828 M1151 M0779 M0253 N0700 N0701 O0195
Benzyltriphenylphosphonium Bromide Benzyltriphenylphosphonium Chloride (Bromomethyl)triphenylphosphonium Bromide 3-Bromopropyltriphenylphosphonium Bromide trans-2-Butene-1,4-bis(triphenylphosphonium Chloride) Butyltriphenylphosphonium Bromide 4-(Carboxybutyl)triphenylphosphonium Bromide (3-Carboxypropyl)triphenylphosphonium Bromide (2-Chlorobenzyl)triphenylphosphonium Chloride (4-Chlorobenzyl)triphenylphosphonium Chloride (Chloromethyl)triphenylphosphonium Chloride Cinnamyltriphenylphosphonium Bromide (Cyanomethyl)triphenylphosphonium Chloride Cyclopropyltriphenylphosphonium Bromide Di-tert-butylmethylphosphonium Tetraphenylborate (2,4-Dichlorobenzyl)triphenylphosphonium Chloride 2-Dimethylaminoethyltriphenylphosphonium Bromide 2-(1,3-Dioxan-2-yl)ethyltriphenylphosphonium Bromide 2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium Bromide (1,3-Dioxolan-2-yl)methyltriphenylphosphonium Bromide 4-Ethoxybenzyltriphenylphosphonium Bromide Ethoxycarbonylmethyl(triphenyl)phosphonium Bromide Ethyltriphenylphosphonium Bromide Ethyltriphenylphosphonium Iodide (Formylmethyl)triphenylphosphonium Chloride Heptyltriphenylphosphonium Bromide Hexyltriphenylphosphonium Bromide (2-Hydroxybenzyl)triphenylphosphonium Bromide Isopropyltriphenylphosphonium Iodide Methoxycarbonylmethyl(triphenyl)phosphonium Bromide (Methoxymethyl)triphenylphosphonium Chloride (N-Methyl-N-phenylamino)triphenylphosphonium Iodide Methyltriphenylphosphonium Bromide Methyltriphenylphosphonium Iodide (1-Naphthylmethyl)triphenylphosphonium Chloride (4-Nitrobenzyl)triphenylphosphonium Bromide μ-Oxo-bis[tris(dimethylamino)phosphonium] Bis(tetrafluoroborate) (=Bates' Reagent)
P1182 T2005 T1416 T1124 T1649
Phenacyltriphenylphosphonium Bromide Tetrabutylphosphonium Benzotriazolate Tetrabutylphosphonium Bis(1,3-dithiole-2-thione-4,5-dithiolato)nickel(III) Complex Tetrabutylphosphonium Bromide Tetrabutylphosphonium Chloride (80% in Water)
[Coupling Reagent for Peptide] [Coupling Reagent for Peptide]
Unit Size 25g 25g 25g 25g 5g
25g
5g 25g 25g 5g
25g 250g 500g 25g 25g 25g 25g 250g 25g 25g 25g 25g 25g 25g 5g 1g 25g 25g 25g 25g 25g 25g 250g 500g 250g 25g 500g 500g 25g 25g 25g 500g 10g 500g 500g 25g 25g
5g 10g 25g
5g 5g
5g 5g 5g 5g 5g 25g 25g 25g 25g 25g 5g 5g 25g 25g 25g 5g
[for Peptide Synthesis]
352
25g 25g
1g 25g 25g 1g 500g 250g
Chemicals itemized in this TCI Reagent Guide are for testing or research purpose only. Therefore, please note those chemicals are not guaranteed in the user's favor relating to various problems under the Patent Law that might occur through their use.
Phosphonium Compounds
Product No. Product Name T2007 T2571 T2006 T2008 T1379 T1746 T1747 T0607 T1089 T1650 T1069 T1375 T1450 T1329 T2603 C1442 T2718 D2912 H1047 T2564 T2680 M1455 O0297 T2584 T2258 T2585 T1458 T1510 T1498 P1438 P1200 T1506 T1644
Tetrabutylphosphonium Hexafluorophosphate Tetrabutylphosphonium Hydroxide (40% in Water) Tetrabutylphosphonium Tetrafluoroborate Tetrabutylphosphonium Tetraphenylborate Tetraethylphosphonium Bromide Tetraethylphosphonium Hexafluorophosphate Tetraethylphosphonium Tetrafluoroborate Tetrakis(hydroxymethyl)phosphonium Chloride (ca. 80% in Water) Tetrakis(hydroxymethyl)phosphonium Sulfate (ca. 70-80% in Water) Tetra-n-octylphosphonium Bromide Tetraphenylphosphonium Bromide Tetraphenylphosphonium Chloride Tetraphenylphosphonium Iodide Tetraphenylphosphonium Tetraphenylborate Tetraphenylphosphonium Tetra-p-tolylborate Tributyl(cyanomethyl)phosphonium Chloride Tributyl(1,3-dioxolan-2-ylmethyl)phosphonium Bromide Tributyldodecylphosphonium Bromide Tributylhexadecylphosphonium Bromide Tributyl(2-methoxyethyl)phosphonium Bis(trifluoromethanesulfonyl)imide Tributylmethylphosphonium Bis(trifluoromethanesulfonyl)imide Tributylmethylphosphonium Iodide Tributyl-n-octylphosphonium Bromide Tri-tert-butylphosphonium Tetrafluoroborate Tri-tert-butylphosphonium Tetraphenylborate Tricyclohexylphosphonium Tetrafluoroborate 2-(Trimethylsilyl)ethoxymethyltriphenylphosphonium Chloride (2-Trimethylsilylethyl)triphenylphosphonium Iodide (3-Trimethylsilyl-2-propynyl)triphenylphosphonium Bromide Triphenylpropargylphosphonium Bromide Triphenylpropylphosphonium Bromide Triphenyl(tetradecyl)phosphonium Bromide Triphenylvinylphosphonium Bromide
Unit Size 25g
5g 5g 25ml 25g 25g 5g 10g 5g 10g
1g 1g 5g 1g 5g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 250g 25g 25g 25g 5g 25g 500ml 500g 25g 500g 25g 25g 25g 25g 25g 5g 25g 25g 5g 5g 25g 25g 5g 1g 5g 25g 5g 5g 25g 500g 25g 5g
353
Iodonium, Sulfonium & Oxonium Compounds
Iodonium, Sulfonium & Oxonium Compounds
B2380
t
B2381
Bu
t
I
D2503
CH3 I
CH3
N
I
PF6
I
D2373
AsF6
D2357
D2243
I
E0467
NO3
I0591 CH3
BF4
CH3
P1080
CH
I F
P1659
CH3
F
ClO4
O CF3(CF2)5
I
CF3
O S CF3
CF3
CF3SO3
P1081 O CF
I
OSO2CF3
CF3(CF2)7
I
O S CF3
O
O
B
F F
P1082
I
I
I
PF6
F 4
P1620
P1239 Si(CH3)3
O I
D2253
I
I
I
Cl
I
D2238
CF3CF2CF2
I
Br
CH3
HC C
BF4
N
D2248
. H2O
C O CH3
I
CF3SO3
D2356 O
N
t Bu
I
PF6
D2372
CH3 CH3
t Bu
N
Iodonium Compounds
B2359
Bu
B2539
O S CF3 O
CH3 CH3
I
Si C C
I
BF4
CH3 CF3SO3
Product No. Product Name B2380 B2381 B2539 B2359 D2372 D2503 D2356 D2248 D2238 D2373 D2357 D2243 D2253 E0467
354
Bis(4-tert-butylphenyl)iodonium Hexafluorophosphate Bis(4-tert-butylphenyl)iodonium Trifluoromethanesulfonate Bis(pyridine)iodonium Tetrafluoroborate Bis(2,4,6-trimethylpyridine)iodonium Hexafluorophosphate Diphenyliodonium Bromide Diphenyliodonium-2-carboxylate Monohydrate Diphenyliodonium Chloride Diphenyliodonium Hexafluoroarsenate Diphenyliodonium Hexafluorophosphate Diphenyliodonium Iodide Diphenyliodonium Nitrate Diphenyliodonium Perchlorate Diphenyliodonium Trifluoromethanesulfonate Ethynyl(phenyl)iodonium Tetrafluoroborate [Ethynylating Reagent]
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 1g 1g 1g 5g 5g 1g
5g 5g 1g
5g 5g 1g 5g 5g 25g 25g 1g 25g 5g 25g 1g 5g 1g
Iodonium, Sulfonium & Oxonium Compounds
Product No. Product Name I0591 P1080 P1659 P1081 P1082 P1620 P1239
Unit Size
4-Isopropyl-4'-methyldiphenyliodonium Tetrakis(pentafluorophenyl)borate (Perfluorohexyl)phenyliodonium Trifluoromethanesulfonate (Perfluoroisopropyl)phenyliodonium Trifluoromethanesulfonate (Perfluoro-n-octyl)phenyliodonium Trifluoromethanesulfonate (Perfluoropropyl)phenyliodonium Trifluoromethanesulfonate Phenyl[2-(trimethylsilyl)phenyl]iodonium Trifluoromethanesulfonate Trimethylsilylethynyl(phenyl)iodonium Tetrafluoroborate
B1151
B3311
S
Sulfonium Compounds
C1240
CH3
C1390
S
CH3
S
(CH2)3Cl
BF4
S
BF4
CH3
O
H1022
M0644 S
CH3
CH3
Br
S
Br CH3
O
D2231
S
O
SCH3
BF4
CH3
C CH2S
T1564
CH3
BF4
T2314
CH3 CH3
CH3
O
BF4
S
S
CH3
Cl
D2685
CH3 HO
D1945
CH3 HO
25g 5g 500mg 1g 1g 1g 1g
C1241
Br BF4
S
C1380
5g 1g
S
HO
CH3
CH2CH3
(CH2)3CH3
Cl CH3(CH2)3
S
I (CH2)3CH3
CH3CH2
S
(CF3SO2)2N CH2CH3
NH2
CH3OSO3 OH
T1771
T1576
CH3
CH3
Br
T1609
CH3
S
CH3
T1833
OH
T1608
CH3
S
CH3
I CH3
T2041
S CH3
I
CH3
CH3
S
BF4
S
PF6 CH3
CH3
CH3
Product No. Product Name B1151 B3311 C1241 C1240 C1380 C1390
CH3
T2042
Br S
O
S CH3 Br CH3
CH3
S
T1065
O
CH3
CH3
CH3 S
T1056
1,3-Benzodithiolylium Tetrafluoroborate [Hydroxyl-Protecting Agent] Bromodimethylsulfonium Bromide (2-Carboxyethyl)dimethylsulfonium Bromide (2-Carboxyethyl)dimethylsulfonium Chloride (3-Chloropropyl)diphenylsulfonium Tetrafluoroborate Cyclopropyldiphenylsulfonium Tetrafluoroborate
CH3 CF3SO3
Unit Size 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 25g 5g 5g 1g 1g
355
Iodonium, Sulfonium & Oxonium Compounds
Product No. Product Name D1945 D2231 D2685 H1022 M0644 T1564 T2314 T1771 T1576 T1056 T1833 T1065 T1609 T1608 T2041 T2042
Unit Size
Dimethyl(methylthio)sulfonium Tetrafluoroborate Dimethylphenacylsulfonium Tetrafluoroborate Diphenyl(methyl)sulfonium Tetrafluoroborate 4-Hydroxyphenyldimethylsulfonium Methyl Sulfate DL-Methionine Methylsulfonium Chloride Tributylsulfonium Iodide Triethylsulfonium Bis(trifluoromethanesulfonyl)imide Trimethylsulfonium Bromide Trimethylsulfonium Hydroxide (0.2mol/L in Methanol) [Methylating Reagent] Trimethylsulfonium Iodide Trimethylsulfoxonium Bromide Trimethylsulfoxonium Iodide Triphenylsulfonium Bromide Triphenylsulfonium Tetrafluoroborate Tri-p-tolylsulfonium Hexafluorophosphate Tri-p-tolylsulfonium Trifluoromethanesulfonate
D2420
1g 1g 1g 5g 25g
25g 5ml 25g
100mg
25g 1g 1g 1g
T1606
5g 5g 5g 25g 500g 1g 5g 100g 25ml 500g 25g 500g 5g 5g 1g 5g
T1507
CH3
CH2CH3
Oxonium Compounds
H3C H 3C C H3C
CH3 O
C CH3
CF3SO3
CH3CH2
O
CH2CH3
CH3 BF4
CH3
O
CH3
BF4
CH3
T2375 CH3 BF4 CH3
O
CH3
Product No. Product Name D2420 T1606 T1507 T2375
356
2,6-Di-tert-butyl-4-methylpyrylium Trifluoromethanesulfonate Triethyloxonium Tetrafluoroborate (15% in Dichloromethane, ca. 1mol/L) [Ethylating Reagent] Trimethyloxonium Tetrafluoroborate 2,4,6-Trimethylpyrylium Tetrafluoroborate
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 5g 5g
5g 100ml 25g 25g
Classes of Boron Compounds
Classes of Boron Compounds
I0658
M1714 CH3
CH3
O
CH3
O
B OCH
Boric Acid Esters
CH3 CH3
CH3
O
CH3
O
CH3(CH2)3O
B2096
O(CH2)9CH3
B
B
O(CH2)3CH3
B2094
CH3(CH2)9O
B0521
B0520
B1178
OCH2CH3 B CH3CH2O OCH2CH3
O N O B O
O(CH2)9CH3
HgOH
CH3
T1291
O(CH2)3CH3
HgOB(OH)2 B OCH3
CH3
B0518
P0769 CH3
T1581
O(CH2)15CH3 CH3(CH2)15O
B
O(CH2)15CH3
B0523
B0522 B0226 OCH3
CH3(CH2)5O
O(CH2)5CH3
OCH(CH3)2
B
B
O(CH2)5CH3
(CH3)2CHO
O OCH(CH3)2 CH3O
B2095
B0524
O(CH2)7CH3 B CH3(CH2)7O O(CH2)7CH3
T2543
(CH3)3SiO
B
O
B
CH3O
B
OCH3
CH3(CH2)17O
3
CH3CH2CH2O
OCH2CH2CH3
B0519
OSi(CH3)3
O(CH2)13CH3
B
B
O(CH2)13CH3
OCH(CF3)2 B O
Cl 3
D0281
(CF3)2CHO
B
CH3
O B OCH2CH2NH2
B O
Product No. Product Name 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Phenylmercuric Borate (mixed Phenylmercury Hydroxide) Tributyl Borate Tridecyl Borate Triethanolamine Borate Triethyl Borate Trihexadecyl Borate Trihexyl Borate Triisopropyl Borate 2,4,6-Trimethoxyboroxin Trimethyl Borate Trimethyl Borate (63-65% in Methanol) Trioctadecyl Borate
OCH(CF3)2
D2943
B O S CF3 O
3
I0658 M1714 P0769 B0518 B2096 T1291 B0520 B1178 B2094 B0521 T1581 B0522 B0226 B0523
O(CH2)17CH3
B1645
OCH2CH2CH3 B
B
OCH3
B1644
O
CH3(CH2)13O
O(CH2)17CH3
OCH3
O
B0134
B2097
OSi(CH3)3
B
B
Unit Size 5g 5g 25ml 25g 25ml
25ml 25g 25ml 25ml
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 25g 25g 500ml 5g 500g 500ml 25g 25g 500ml 100g 500ml 500ml 25g
357
Classes of Boron Compounds
Product No. Product Name B2095 B0524 B0134 B1644 B1645 T2543 B2097 B0519 D0281 D2943
Unit Size
Tri-n-octyl Borate Triphenyl Borate Tripropyl Borate Tris(4-chlorophenyl) Borate Tris(hexafluoroisopropyl) Borate Tris(trimethylsilyl) Borate Tritetradecyl Borate Tri-o-tolyl Borate 2-Aminoethyl Diphenylborinate Dicyclohexyl(trifluoromethanesulfonyloxy)borane
25g 500g 500ml 5g 5g 25g 25g 25ml 25g 5g
25g 25ml 1g
5ml 10g 1g
A1942
A1907
A1281 B(OH)2 B(OH)2
B(OH)2
. H2O
O
Boronic Acids
C CH3
NH2
C CH3 O
A1774
A1843
B2978
B2893
B3056 B(OH)2
B(OH)2
B(OH)2
. 1/2H2SO4
O
NH2
B2145
B2489
S
B(OH)2
B2294
B(OH)2
B2490
OCH2
B3022 B(OH)2
B(OH)2 CH2O
CF3 B(OH)2
B(OH)2
(HO)2B
B(OH)2
CF3
B1886
B2860
B2889
B(OH)2
B1858
Br
B(OH)2
CF3
B3307
B(OH)2
B(OH)2
B(OH)2 Br
CF3
B2890
Br
B2862
B0529
B2589
Br
B2251 B(OH)2
B(OH)2 (HO)2B N
Br
Br
S
B(OH)2
CH3
B(OH)2 CH3 C CH3
(CH2)3CH3
C2385
C2028
C1353
C1760 B(OH)2
B(OH)2
O2N
B(OH)2
O
O
C OH
C OH
C2386 B(OH)2
B(OH)2 Cl
C OH O
358
CH3
Cl F
Availability, price or specification of the listed products are subject to change without prior notice.
OCH3
Classes of Boron Compounds
C2292
C1705
C1613
B(OH)2
C2288 B(OH)2
B(OH)2
B(OH)2
OCH3
C1473
(HO)2B
Cl
Cl
N
Cl
C2066
C2416
C2031
C1778
C2188 B(OH)2
B(OH)2
B(OH)2
Cl
Cl
B(OH)2
CN Cl
S
B(OH)2 CN
D3434
D2494
D3044
D3357
B(OH)2
B(OH)2
Cl
Cl
D3523
D3436
F
D3861
F
N
D3522
B(OH)2
OCH3 CH3O
OCH3
D3516
D3514 B(OH)2
B(OH)2
B(OH)2
CH3
CH3
OCH3 OCH3 OCH3
D3517
B(OH)2
OCH3
OCH3
D3513
B(OH)2
F
B(OH)2
OCH3
D3512
CH3O
D3521 B(OH)2
F
F
F
D3853
B(OH)2
B(OH)2
F
F
D4006
F
B(OH)2
F
F
B(OH)2
D3087
B(OH)2
B(OH)2
Cl
D3081
Cl Cl
F Cl
Cl
Cl
D3391
B(OH)2
B(OH)2
B(OH)2
Cl
Cl
D2909
D3783
B(OH)2
Cl
Cl
CN
D3633
CH3O
CH3
OCH3
D3396
D3537
CH3
D3823 B(OH)2
B(OH)2 CH3
B(OH)2
B(OH)2 CH3
CH3
CH3
E0723
E0724 B(OH)2
S
CH3
E0725 B(OH)2
N
CH3
E0818 B(OH)2
S
S
B(OH)2
E0720 B(OH)2
B(OH)2
CH2CH3
OCH2CH3 OCH2CH3
OCH2CH3
CH2CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
359
Classes of Boron Compounds
F0280
F0664
F0683
F0712
F0666
B(OH)2 B(OH)2 Fe
B(OH)2
B(OH)2
F
B(OH)2
CH3
Fe B(OH)2
F CH3
F0697
F0407
CH3
F0404
B(OH)2
F0361
F0548 B(OH)2
B(OH)2
B(OH)2
F
F
O H C
CH3
F
F
F0611
B1873
F0446
H C
O
F0549
B(OH)2
O
B(OH)2
H C CHO
F0394
F0438
H0913
H1244
H1280
CH2OH
H1185
I0597 B(OH)2 CH3
OH
O
B(OH)2 CH3
OH
I0620
CH2OH
H1228 B(OH)2
B(OH)2 B
B(OH)2
B(OH)2
O
H1184
OH
M1905
M1906
OH
M1907
M1261 B(OH)2
B(OH)2 B(OH)2
B(OH)2
B(OH)2 OCH3
C OCH3 O
O CH
CH3
C OCH3
C OCH3
CH3
M1322
O
M1252
M1553
M2035
M1127 B(OH)2
B(OH)2
B(OH)2
(HO)2B
O
CH3B(OH)2
CH3
OCH3
M1314 B(OH)2
NO2
O
OCH3
M1313
B(OH)2
H1204 B(OH)2
CH3
B(OH)2
S
CHO
B(OH)2 O
B(OH)2
B(OH)2
CHO
O
S
F
F0445 B(OH)2
S
M1126 B(OH)2
M1972
M1850
B(OH)2
B(OH)2
CH3
SO2CH3
CH3 CH3 CH3
360
Availability, price or specification of the listed products are subject to change without prior notice.
S
B(OH)2
Classes of Boron Compounds
M1570
M1793
M1458
N0630 B(OH)2
B(OH)2
B(OH)2
N0649 B(OH)2
B(OH)2
SCH3 SCH3
N0798
N0811
SCH3
N0563
N0812
P1093
B(OH)2
B(OH)2
B(OH)2
B(OH)2 NO2
NO2
B0857
P1358
B(OH)2
NO2
P1625
P1673
P1594
B(OH)2
B(OH)2
B(OH)2
B(OH)2 (HO)2B
B(OH)2 N
P1759
Q0080
(HO)2B
S0831
T2412
B(OH)2
N N
T2621 B(OH)2
B(OH)2
S S
N
T1772
T1975
T2413
T2362
B(OH)2
OCF3
T1793
T1788
T2654
B(OH)2
B(OH)2
CH3
B(OH)2 CH
CH
F
CF3
T2664
CH3
F
CF3
T1960
OCF3
T2574
B(OH)2
B(OH)2
B(OH)2
OCF3
S
T1800
CF3
T2640
D3435
CH3
CH3
T2430 F
B(OH)2
Cl
F
CH3 O B
Si(CH3)3
CH3
B O
O B
O B
Cl
B O
O B
Cl
T1814
T1887
T1929
B
O
Cl
F
O B
B O
O B
F F
V0075 B(OH)2
F
CH2 CH B
F
F F
O
Cl
T2498
F
F
CH3 CH3
CH3
CH
F
Cl
B(OH)2
B(OH)2
T1773 B(OH)2
B(OH)2
B(OH)2 S
N
O B
O
B O
O B
O B
F
B
B O
O
O B
F F
F
O B
B
CH CH2
O
CH CH2
F F
B
N
CH CH2
F
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
361
Classes of Boron Compounds
Product No. Product Name A1942 A1907 A1281 A1774 A1843 B2978 B2893 B3056 B2145 B2489 B2294 B2490 B3022 B1886 B2860 B2889 B2890 B1858 B3307 B2862 B0529 B2589 B2251 C2385 C2028 C1353 C1760 C2386 C2292 C1705 C1613 C1473 C2288 C2066 C2416 C2031 C1778 C2188 D3434 D2494 D3044 D3357 D3783 D2909 D3523 D3391 D3436 D3087 D3081 D4006 D3853 D3521 D3522 D3861 D3512 D3513 D3516 D3514 D3517 D3633 D3396 D3537 D3823 E0723 E0724 E0725 E0818 E0720
362
3-Acetylphenylboronic Acid (contains varying amounts of Anhydride) 4-Acetylphenylboronic Acid (contains varying amounts of Anhydride) 3-Aminophenylboronic Acid Monohydrate (contains varying amounts of Anhydride) 3-Aminophenylboronic Acid Hemisulfate 2-Anthraceneboronic Acid (contains varying amounts of Anhydride) Benzofuran-2-boronic Acid (contains varying amounts of Anhydride) Benzo[b]thiophene-2-ylboronic Acid (contains varying amounts of Anhydride) 3-Benzyloxyphenylboronic Acid (contains varying amounts of Anhydride) 4-Benzyloxyphenylboronic Acid (contains varying amounts of Anhydride) 3-Biphenylboronic Acid (contains varying amounts of Anhydride) 4-Biphenylboronic Acid (contains varying amounts of Anhydride) 4,4'-Biphenyldiboronic Acid 2,4-Bis(trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride) 3,5-Bis(trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride) 4'-Bromo-4-biphenylboronic Acid (contains varying amounts of Anhydride) 2-Bromophenylboronic Acid (contains varying amounts of Anhydride) 3-Bromophenylboronic Acid (contains varying amounts of Anhydride) 4-Bromophenylboronic Acid (contains varying amounts of Anhydride) 2-Bromopyridine-5-boronic Acid (contains varying amounts of Anhydride) 5-Bromo-2-thiopheneboronic Acid (contains varying amounts of Anhydride) Butylboronic Acid (contains varying amounts of Anhydride) [for Esterification] 4-Butylphenylboronic Acid (contains varying amounts of Anhydride) 4-tert-Butylphenylboronic Acid (contains varying amounts of Anhydride) 3-Carboxy-5-nitrophenylboronic Acid (contains varying amounts of Anhydride) 3-Carboxyphenylboronic Acid (contains varying amounts of Anhydride) 4-Carboxyphenylboronic Acid (contains varying amounts of Anhydride) 3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) 2-Chloro-4-methoxyphenylboronic Acid (contains varying amounts of Anhydride) 5-Chloro-2-methoxyphenylboronic Acid (contains varying amounts of Anhydride) 2-Chlorophenylboronic Acid (contains varying amounts of Anhydride) 3-Chlorophenylboronic Acid (contains varying amounts of Anhydride) 4-Chlorophenylboronic Acid (contains varying amounts of Anhydride) 2-Chloropyridine-5-boronic Acid (contains varying amounts of Anhydride) 5-Chloro-2-thiopheneboronic Acid (contains varying amounts of Anhydride) 2-Cyanophenylboronic Acid (contains varying amounts of Anhydride) 3-Cyanophenylboronic Acid (contains varying amounts of Anhydride) 4-Cyanophenylboronic Acid (contains varying amounts of Anhydride) Cyclohexylboronic Acid (contains varying amounts of Anhydride) 2,3-Dichlorophenylboronic Acid (contains varying amounts of Anhydride) 2,4-Dichlorophenylboronic Acid (contains varying amounts of Anhydride) 2,5-Dichlorophenylboronic Acid (contains varying amounts of Anhydride) 2,6-Dichlorophenylboronic Acid (contains varying amounts of Anhydride) 3,4-Dichlorophenylboronic Acid (contains varying amounts of Anhydride) 3,5-Dichlorophenylboronic Acid (contains varying amounts of Anhydride) 2,3-Difluorophenylboronic Acid (contains varying amounts of Anhydride) 2,4-Difluorophenylboronic Acid (contains varying amounts of Anhydride) 2,5-Difluorophenylboronic Acid (contains varying amounts of Anhydride) 2,6-Difluorophenylboronic Acid (contains varying amounts of Anhydride) 3,5-Difluorophenylboronic Acid (contains varying amounts of Anhydride) 2,6-Difluoro-3-pyridineboronic Acid (contains varying amounts of Anhydride) 2,3-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) 2,4-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) 2,5-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) 2,6-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) 3,4-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) 3,5-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride) 2,3-Dimethylphenylboronic Acid (contains varying amounts of Anhydride) 2,4-Dimethylphenylboronic Acid (contains varying amounts of Anhydride) 2,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride) 2,6-Dimethylphenylboronic Acid (contains varying amounts of Anhydride) 3,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride) 4-(Diphenylamino)phenylboronic Acid (contains varying amounts of Anhydride) Dithieno[3,2-b:2',3'-d]thiophene-2-boronic Acid (contains varying amounts of Anhydride) 2-Ethoxyphenylboronic Acid (contains varying amounts of Anhydride) 3-Ethoxyphenylboronic Acid (contains varying amounts of Anhydride) 4-Ethoxyphenylboronic Acid (contains varying amounts of Anhydride) 2-Ethylphenylboronic Acid (contains varying amounts of Anhydride) 4-Ethylphenylboronic Acid (contains varying amounts of Anhydride)
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 5g 1g 1g 5g 1g 5g 250mg 1g
5g 1g 5g 5g 1g 1g
1g 1g
1g
1g
1g
5g 5g 1g 1g 5g 1g 5g 1g 1g 1g 1g 1g 5g 1g 5g 5g 1g 1g 1g 5g 5g 1g 5g 5g
5g 5g 5g 5g 1g 5g 1g
1g
1g
1g 1g 5g 5g 5g 1g 5g 1g 5g 200mg 1g 1g
5g
25g 5g 25g 25g 1g 1g 25g 5g 5g 25g 25g 1g 5g 5g 1g 5g 25g 25g 5g 5g 25g 5g 25g 5g 5g 5g 5g 5g 25g 5g 25g 25g 5g 5g 5g 25g 25g 5g 25g 25g 5g 5g 25g 5g 25g 25g 25g 5g 25g 5g 5g 5g 5g 25g 25g 25g 5g 5g 25g 5g 25g 1g 1g 5g 5g 5g 5g 25g
Classes of Boron Compounds
Product No. Product Name F0280
Ferroceneboronic Acid (contains varying amounts of Anhydride)
F0664 F0683 F0712 F0666 F0697 F0407 F0404 F0361 F0548 F0611 B1873 F0445 F0446 F0549 F0394 F0438 H0913 H1244 H1204 H1280 H1184 H1185 H1228 I0597 I0620 M1905 M1906 M1907 M1261 M1322 M1252 M1553 M2035 M1127 M1313 M1314 M1126 M1972 M1850 M1570 M1793 M1458 N0630 N0649 N0798 N0811 N0563 N0812 P1093 B0857 P1358 P1625 P1673 P1594 P1759 Q0080 S0831 T2412 T2621 T1772 T1975 T2413 T2362 T1773 T1800 T1793 T1788
1,1'-Ferrocenediboronic Acid (contains varying amounts of Anhydride) 2-Fluoro-4-methylphenylboronic Acid (contains varying amounts of Anhydride) 3-Fluoro-4-methylphenylboronic Acid (contains varying amounts of Anhydride) 4-Fluoro-2-methylphenylboronic Acid (contains varying amounts of Anhydride) 4-Fluoro-3-methylphenylboronic Acid (contains varying amounts of Anhydride) 2-Fluorophenylboronic Acid (contains varying amounts of Anhydride) 3-Fluorophenylboronic Acid (contains varying amounts of Anhydride) 4-Fluorophenylboronic Acid (contains varying amounts of Anhydride) 5'-Formyl-2,2'-bithiophene-5-boronic Acid (contains varying amounts of Anhydride) 5-Formyl-2-furanboronic Acid (contains varying amounts of Anhydride) 2-Formylphenylboronic Acid (contains varying amounts of Anhydride) 3-Formylphenylboronic Acid (contains varying amounts of Anhydride) 4-Formylphenylboronic Acid (contains varying amounts of Anhydride) 5-Formyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride) 2-Furylboronic Acid (contains varying amounts of Anhydride) 3-Furylboronic Acid (contains varying amounts of Anhydride) Hexylboronic Acid (contains varying amounts of Anhydride) 3-(Hydroxymethyl)phenylboronic Acid (contains varying amounts of Anhydride) 4-(Hydroxymethyl)phenylboronic Acid (contains varying amounts of Anhydride) 2-(Hydroxymethyl)phenylboronic Acid Cyclic Monoester 2-Hydroxyphenylboronic Acid (contains varying amounts of Anhydride) 3-Hydroxyphenylboronic Acid (contains varying amounts of Anhydride) 4-Hydroxyphenylboronic Acid (contains varying amounts of Anhydride) Isobutylboronic Acid (contains varying amounts of Anhydride) 4-Isopropylphenylboronic Acid (contains varying amounts of Anhydride) 2-(Methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride) 3-(Methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride) 4-(Methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride) 2-Methoxyphenylboronic Acid (contains varying amounts of Anhydride) 3-Methoxyphenylboronic Acid (contains varying amounts of Anhydride) 4-Methoxyphenylboronic Acid (contains varying amounts of Anhydride) Methylboronic Acid (contains varying amounts of Anhydride) 3,4-(Methylenedioxy)phenylboronic Acid (contains varying amounts of Anhydride) 4-Methyl-3-nitrophenylboronic Acid (contains varying amounts of Anhydride) 2-Methylphenylboronic Acid (contains varying amounts of Anhydride) 3-Methylphenylboronic Acid (contains varying amounts of Anhydride) 4-Methylphenylboronic Acid (contains varying amounts of Anhydride) 4-(Methylsulfonyl)phenylboronic Acid (contains varying amounts of Anhydride) 5-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride) 2-(Methylthio)phenylboronic Acid (contains varying amounts of Anhydride) 3-(Methylthio)phenylboronic Acid (contains varying amounts of Anhydride) 4-(Methylthio)phenylboronic Acid (contains varying amounts of Anhydride) 1-Naphthaleneboronic Acid (contains varying amounts of Anhydride) 2-Naphthaleneboronic Acid (contains varying amounts of Anhydride) 4-(1-Naphthyl)phenylboronic Acid (contains varying amounts of Anhydride) 2-Nitrophenylboronic Acid (contains varying amounts of Anhydride) 3-Nitrophenylboronic Acid (contains varying amounts of Anhydride) 4-Nitrophenylboronic Acid (contains varying amounts of Anhydride) 9-Phenanthreneboronic Acid (contains varying amounts of Anhydride) Phenylboronic Acid (contains varying amounts of Anhydride) 1,4-Phenylenediboronic Acid (contains varying amounts of Anhydride) 1-Pyreneboronic Acid (contains varying amounts of Anhydride) 3-Pyridylboronic Acid (contains varying amounts of Anhydride) 4-Pyridylboronic Acid (contains varying amounts of Anhydride) 5-Pyrimidylboronic Acid (contains varying amounts of Anhydride) Quinoline-3-boronic Acid (contains varying amounts of Anhydride) 9,9'-Spirobi[9H-fluorene]-2-boronic Acid 2-p-Terphenylboronic Acid (contains varying amounts of Anhydride) Thieno[3,2-b]thiophene-2-boronic Acid (contains varying amounts of Anhydride) 2-Thiopheneboronic Acid (contains varying amounts of Anhydride) 3-Thiopheneboronic Acid (contains varying amounts of Anhydride) 2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) 3-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) 4-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) 2-(Trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride) 3-(Trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride) 4-(Trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride)
Unit Size 100mg
[Cyclic boronating reagent for GC/MS]
1g
1g
1g 1g
1g
1g 1g
5g 1g 1g 1g
1g
1g
1g 1g 1g 5g 5g 5g 5g 1g 1g 5g 1g 1g 1g 1g 1g 1g 1g 1g 1g 1g 1g 5g 1g 1g 5g 5g 1g 5g 1g 5g 1g 5g 5g 1g 1g 1g 1g 5g 5g 1g 1g 5g 100mg 25g 5g 5g 5g 1g 100mg 1g 1g
5g 1g 1g 5g 5g 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
1g 1g 5g 5g 5g 25g 25g 25g 25g 1g 5g 5g 25g 5g 5g 5g 5g 5g 5g 5g 5g 5g 5g 5g 25g 5g 5g 5g 25g 25g 5g 25g 5g 25g 5g 5g 25g 25g 5g 5g 5g 5g 5g 25g 25g 5g 5g 25g 1g 1g 250g 25g 25g 25g 5g 1g 5g 5g 1g 1g 25g 5g 5g 5g 25g 25g 5g 5g
363
Classes of Boron Compounds
Product No. Product Name T2574 T2654 T1960 T2664 T2640 D3435 T2430 T1814 T1887 T1929 T2498 V0075
Unit Size
2,3,4-Trifluorophenylboronic Acid (contains varying amounts of Anhydride) 2,4,6-Triisopropylphenylboronic Acid (contains varying amounts of Anhydride) 2,4,6-Trimethylphenylboronic Acid 4-(Trimethylsilyl)phenylboronic Acid (contains varying amounts of Anhydride) 2,4,6-Triphenylboroxin 2,4,6-Tris(3,4-dichlorophenyl)boroxin 2,4,6-Tris(3,4-difluorophenyl)boroxin 2,4,6-Tris(4-fluorophenyl)boroxin 2,4,6-Tris(m-terphenyl-5'-yl)boroxin 2,4,6-Tris(3,4,5-trifluorophenyl)boroxin 2,4,6-Trivinylboroxin - Pyridine Complex 4-Vinylphenylboronic Acid (contains varying amounts of Anhydride)
A2086
A2157
CH3 CH3
O
CH3
CH3
O
B3151
O
O
CH3
O B O
CH3
B
CH3
O
O B O
CH3 CH3 CH3 O O B
CH3 CH3
N O
CH3
CH3
B3501
B3199 O B O
Fe
O B O
CH3
CH3 CH3
CH3
S
CH3
O
O(CH2)3CH3
CH3
O
O
CH3
CH3
O CH3(CH2)7
CH3
CH3
Cl
O
CH3
S
O
S
Br
O
CH3
B
CH3
CH3
O
D3649
N
CH2CH3 CH2CH3
OCH(CH3)2
OCH(CH3)2 BrCH2 B
CH2 CHCH2 B
OCH(CH3)2
OCH(CH3)2
CH3
F0531
D2853 CH3
CH3 CH3
O
CH3
O
B
CH3
N
CH3
CH3
O
CH3
O
CH3
CH3 N
CH3
O
O
CH3
O
CH3
CH3
CH3 OH
B
B
CH3
CH3
H1298
E0667
H1294
CH3
CH3
H1280
O CH3CH2O C O CH3 B CH3 O
I0653
CH3(CH2)5 F
364
CH3 CH3
C2004
B
D3772
B
CH3
O B O
CH3
(CH2)7CH3 O
CH3
CH3 CH3
B
D3832 CH3
CH3
O B
CH3
D3533
CH3
CH3
CH3 O B
D3738
O(CH2)3CH3
CH3
O
CH3
CH3
O
CH3
Br
CH3
CH2 CH B
B
O
S
O
CH3
B
CH3
O
D3601
O
CH3
CH3
O
CH3
CH3
CH3
B
O
CH3
D3596
CH3
CH3 O
O
B
O
B CH2
CH3 CH3 CH3
B CH2Br
CH3 CH3
C2276
B
CH3 CH3
O
O
B3582
B3200
CH3
CH3 CH3
CH3
CH3
CH3 CH3
N S
B2828
CH3 CH3
O
CH3
B3363 CH3
CH3 B CH2CH CH2
CH3
B3573
CH3 CH3
CH3
O
CH3
B3019
B3448
CH3 B CH C CH2
Boronic Acids Esters
5g 5g 5g 5g 25g 25g 25g 10g 100mg 1g 5g 1g 5g 1g 5g 1g 1g 1g 5g 5g 5g
CH3 CH3
CH3
CH3
O
B O
S
CH3
O
CH3
O
(CH2)5CH3 B
CH3
S
B
CH3
O
CH3
O
O
OH
CH3
Availability, price or specification of the listed products are subject to change without prior notice.
I B
CH3
Classes of Boron Compounds
M2071
N0824
P1855
CH3
CH3 CH3
O
CH3
O
CH3 B CH2
CH3
O
CH3 CH3
O
I0739
CH3
O
B
CH3 S
S
CH3
O
CH3
O
O
B
N H
T1954
T2345
CH3 CH3
O
CH3
O
B CH3
O
CH3
O
CH3
O
B
OH CH3
CH3
CH3
O
CH3
OH
CH3
O
CH3
O
B
CH3
CH3
T2428
CH3
O
CH3
CH3
O
CH3
O
CH3
O
CH3
2-Allenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (stabilized with Phenothiazine) 2-Benzyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(4-Biphenylyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 4,4'-Bis(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)biphenyl 4,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,1,3-benzothiadiazole 5,5'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2'-bithiophene 2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-di-n-octylfluorene 1,1'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ferrocene 2-(Bromomethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(2-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 5-Bromo-5'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2'-bithiophene 2-(2-Chlorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane 2-Cyclopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Dibutyl Vinylboronate (stabilized with Phenothiazine) N,N-Diethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline Diisopropyl Allylboronate Diisopropyl (Bromomethyl)boronate 2-(3,5-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane N,N-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole 2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Ethyl 2-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoate 2-(2-Fluorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane 3-Hexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene 4-Hexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene 2-(Hydroxymethyl)phenylboronic Acid Cyclic Monoester 2-(2-Iodophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(4-Methoxybenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 2-Phenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 4'-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acetanilide 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2'-bithiophene 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CF3 B
B CH CH2
N
Product No. Product Name A2086 A2157 B3448 B3019 B3151 B3573 B3363 B3582 B3501 B3199 B2828 B3200 C2004 C2276 D3596 D3601 D3738 D3649 D3533 D3832 D3772 D2853 E0667 F0531 H1298 H1294 H1280 I0653 M2071 N0824 P1855 T1950 T1951 T2518 I0590 I0739 T1952 T1953 T1954 T2345
NH2
B
CH3 B
N
O
HO
O
CH3 O
CH3
T1953
T2297
CH3
O
C CH3
B
T2349
CH3
CH3
CH3
CH3
N
CH3
NH
CH3
CH3
B
CH3
O
T1952 CH3
CH3
O
CH3
O
CH3
CH3
CH3
CH3
O B
O
CH3
I0590
CH3
CH3
B
CH3
T2518
T1951
CH3
O
NH2
B CH3
CH3
NO2
O
OCH3
CH3
T1950
CH3
Unit Size 1g 1g 1g
1g 1g 1g
1g 1g 1g 1g 1g 1g 1g
1g 1g
5g 1g 1g 1g 1g 1g 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 5g 5g 5g 1g 1g 5g 1g 5g 5g 5g 1g 1g 5g 5g 1g 5g 5g 5g 5g 5g 5g 1g 1g 5g 5g 5g 1g 5g 1g 25g 1g 5g 5g 1g 5g 5g 5g 5g 5g
365
Classes of Boron Compounds
Product No. Product Name T2349 T2297 T2428
Unit Size
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 4,4,5,5-Tetramethyl-2-vinyl-1,3,2-dioxaborolane (stabilized with Phenothiazine) 2-[2-(Trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
B2906
B2254
O
O B
Diboron Esters
CH3
CH3 O
CH3
O
CH3
CH3 CH3
CH3
O
M0898
B1827 CH3 CH3
.
CH3 C NH2
CH3
. BH3
CH3
B Cl BH3 CH3
O
D3890
2
D1842 CH3 CH3
B(CH2CH3)2 BH3
CH3
CH2CH3
B
CH3
F CH3 CH3
N
CH3NHCH3
. BH3
2
D1843
T1180
T1984
CH2CH3
. BH3
CH3CH2 N
T1789
T1181
CH2CH3
. BH3 CH3CH2
CH2CH3
B
T1757
CH3 CH3 N
CH2CH3
. BH3
CH3
T2313 F
BH3
F
F
B F
366
CH3
C CH3
CH3
N
P
5g 25g 25g
C1614
.
N
CH2CH3
CH3
. 2BH3
. BH3
D2661
B Cl
1g 5g 5g
CH3
CH3 C S(CH2)2S
CH3
CH3SCH3
CH3 CH3
CH3
D2581
CH3
O
O
B1264
T2346
. BH3
O
C2023 C1615
BH3 P CH3 C(CH3)3
B1569 H N
CH3
CH3
1g 1g
BH3 (CH3)3C P CH3
Boranes
N
CH3
Unit Size
B2089
. BH3
O
CH3
Bis(hexylene Glycolato)diboron Bis(neopentyl Glycolato)diboron Bis(pinacolato)diboron
B3018
CH3
O B B
Product No. Product Name B2906 B2254 B1964
CH3
B B
O
CH3
O
CH3
B
O
5g 25g 5g
B1964
CH3
CH3
1g 5g
1g
F
3
Availability, price or specification of the listed products are subject to change without prior notice.
P 3
B 3
Classes of Boron Compounds
Product No. Product Name
Unit Size
B2089 B1827 B1264 B3018 M0898 B1569 T2346
(S,S)-1,2-Bis[(tert-butyl)methylphosphino]ethane Bis(borane) 1,2-Bis(tert-butylthio)ethane Borane Borane - tert-Butylamine Complex Borane - 2-Methylpyridine Complex Borane - Morpholine Complex Borane - Pyridine Complex Borane - Tetrahydrofuran Complex (8.5% in Tetrahydrofuran, ca. 0.9mol/L)
100mg 1g 25g 5g 25g 5g 25g 25ml 250ml
C1614 C2023 C1615 D2581 D2661 D3890 D1842 D1843 T1180 T1984 T1181 T1757 T1789 T2313
(+)-B-Chlorodiisopinocampheylborane (58% in Hexane, ca. 1.6mol/L) (-)-B-Chlorodiisopinocampheylborane (60% in Heptane, ca. 1.7mol/L) (-)-B-Chlorodiisopinocampheylborane (60% in Hexane, ca. 1.7mol/L) N,N-Diethylaniline Borane Diethyl(3-pyridyl)borane Dimesitylfluoroborane Dimethylamine Borane Dimethyl Sulfide Borane Triethylamine Borane Triethylborane (ca. 1mol/L in Tetrahydrofuran) Trimethylamine Borane Triphenylborane - Triphenylphosphine Complex Triphenylphosphine Borane Tris(pentafluorophenyl)borane
100ml
(stabilized with Sodium Borohydride)
B1139
25g 1g 25g
5g 1g
L0186
L0164
P 3
Borohydrides
Cu
500ml 100ml 100ml 100ml 100g 1g 5g 500g 25ml 25g 100ml 25g 25g 25g 5g
CH(CH3)CH2CH3
. BH4
LiBH4
Li
H B CH(CH3)CH2CH3 CH(CH3)CH2CH3
P 3
P1439
P1681
P1380
P1441
P1440 CH3
H
N
N
N B N
K
H 3C
CH3
KBH4
CH3CH2CH
H
3
H3C N
N N
BH
B
N
N B
K H3C N
N
N H K
N
CH3
N H K
N
N
H3C
S0480
S0396
S0394
S0810
OCH(CF3)2
OAc NaBH4
Na
NaBH3CN
AcO B H
H B OCH(CF3)2 OCH(CF3)2
OAc
T0837
T0852
CH2CH3
CH3 N CH3
CH2CH3
CH3
CH3
BH4
Bu
N Bu
BH4
Bu
OAc
CH3 N CH3 AcO B H CH3
OAc
Product No. Product Name B1139 L0186 L0164 P1439 P1681 P1380
Bu Na
T1553
CH3
CH3CH2 N CH2CH3 BH4
T0917
Bis(triphenylphosphine)copper Tetrahydroborate Lithium Borohydride (ca. 3mol/L in Tetrahydrofuran) Lithium Tri-sec-butylborohydride (21% in Tetrahydrofuran, ca. 1.0mol/L) Potassium Bis(1-pyrazolyl)borohydride Potassium Borohydride Potassium Tri-sec-butylborohydride (ca. 1.0mol/L in Tetrahydrofuran)
Unit Size
1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
5g 100ml 100ml 5g 100g 100ml
367
Classes of Boron Compounds
Product No. Product Name
Unit Size
P1441 P1440 S0480 S0396 S0394 S0810 T0917 T0837 T0852 T1553
5g 1g 100g 25g 25g
Potassium Tris(3,5-dimethylpyrazol-1-yl)borohydride Potassium Tris(1-pyrazolyl)borohydride Sodium Borohydride Sodium Cyanoborohydride [Reducing Agent] Sodium Triacetoxyborohydride Sodium Tris(1,1,1,3,3,3-hexafluoroisopropoxy)borohydride Tetrabutylammonium Borohydride [Reducing Reagent] Tetraethylammonium Borohydride Tetramethylammonium Borohydride [Reducing Reagent] Tetramethylammonium Triacetoxyborohydride
D3330
5g 5g 5g 5g
I0591 CH3 CH3
CH3
I F
B
P H
L0158
CH
C(CH3)3
Tetraphenylborates
C(CH3)3
A5131
A5130
F
F
Li
B
B
F
F
4
. nEt2O
F 4
T1480
T1329
F
Cl
Cl
F
CH3
F
F F
A5132
25g 5g 500g 250g 100g 5g 25g 25g 25g 25g
B
Cl
F
K
B
F
Na
B
Na
[CH3(CH2)3]4N
B
B
P
F
. xH2O
Cl
T2603
T2258 CH3
C(CH3)3 (CH3)3C P H
P CH3
B
CH3
C(CH3)3 (C6H5)4B
CH3
Product No. Product Name
Unit Size
D3330 I0591 L0158 A5132 A5131
Di-tert-butylmethylphosphonium Tetraphenylborate 4-Isopropyl-4'-methyldiphenyliodonium Tetrakis(pentafluorophenyl)borate Lithium Tetrakis(pentafluorophenyl)borate - Ethyl Ether Complex Potassium Tetrakis(4-chlorophenyl)borate [Anion for the neutral carrier type ion electrode] Sodium Tetrakis(4-fluorophenyl)borate Hydrate [Precipitation reagent for Cs and titrimetric reagent
A5130 T1480 T1329 T2603 T2258
Sodium Tetraphenylborate [Precipitation reagent for K] Tetrabutylammonium Tetraphenylborate Tetraphenylphosphonium Tetraphenylborate Tetraphenylphosphonium Tetra-p-tolylborate Tri-tert-butylphosphonium Tetraphenylborate
1g 25g 5g 5g
5g 1g 1g 1g 1g 1g
for nonionic surfactants]
5g 10g 5g 25g 25g 1g
5g
A2065
A1861
B1151
O NH C CH3
Tetrafluoroborates
CH3
CH3 CH3
N O
368
CH3
N N
N
N
O C
S
BF4 N(CH3)2 N(CH3)2
BF4
Availability, price or specification of the listed products are subject to change without prior notice.
S
BF4
Classes of Boron Compounds
B1658
B2090
B2091
B3114
B1036 N N
N BF4
N
N
N(CH3)2
O C
BF4
Rh
(CH3)3C P
N(CH3)2
CH3
N
C1380
CH3
C2410
S
BF4 O
(CH2)3CH3
(CH2)3CH3
C2421
C1375
CH2CH3
N BF4
N
CH3
(CH2)3Cl
N
BF4
Cl
N
C
D3620
D3621 N
H
D3475
N
S
N
N
BF4
N BF4
CH2CN
D3476
D3711
D3622
CH3
O CH2 N CH2 CH2Ph CH3
CH3
2
2
2BF4
CH3 CH2Ph CH2 N CH2 O
CH3
O CH2 N CH2 CH2Ph CH3
CH3 2BF4
N
2
C CH3
2
N
CH3
N
N
BF4
CH3 C CH3
D2231
CH3 CH3
S
D2685
SCH3
CH3
C CH2S
CH3
BF4
CH3
BF4
N
BF4
CH
E0496
S
N
CH3
CH3
CH
CH3 CH3 BF4
CH3 CH3
E0467 CH3
N
O
BF4
CH
CH3
CH3
CH
CH3
D1945
BF4
D3623
CH3 CH3 CH2Ph CH2 N CH2 O
BF4
Cl
C1390
BF4
Cu(BF4)2
BF4
Br
Br
C0905 N
BF4
N
CH2CH3
Rh
C(CH3)3
B2195
N
BF4
2
P
CH3
B2475
BF4
CH3
HC C
I
BF4
BF4
N CH2CH3
F0358
F0344
F0334
F0343
F0346 CH3
N
F 2BF4
N
Cl
CH2Cl
N
Cl
BF4
F
H0734
H1099
N BF4
N
CH3
B2F7
BF4
BF4
N
CH3
F
F
L0133
CH3 CH3(CH2)15 N CH3
N
N
N0137
N0634 N N
CH3 BF4
LiBF4
O N
BF4 O
(CH2)5CH3
S0446
(CH3)2N
T2006
T0914 T2648
(CH3)2N
N(CH3)2 2BF4
(CH2)3CH3
AgBF4
CH3(CH2)3 N
(CH2)3CH3 BF4
(CH2)3CH3
CH3 N CH3
O C BF4
N CH3 CH3
T0983
N(CH3)2
(CH3)2N P O P N(CH3)2
CH3
F
NO2
O0195
N
(CH2)3CH3 CH3(CH2)3 P
(CH2)3CH3 BF4
(CH2)3CH3
CH2CH3 CH3CH2 N CH2CH3 BF4 CH2CH3
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
369
Classes of Boron Compounds
T1747
T2666
T0842
T2224
T2584
O
CH3
CH2CH3 CH3CH2 P CH2CH3 BF4
(CH3CN)4Cu
BF4
CH3 N CH3
CH2CH3
BF4
N O C
CH3
N(CH3)2 N(CH3)2
C(CH3)3 BF4
(CH3)3C P H
BF4
C(CH3)3
O
T2585
T2198
T1606
BF4
P1239
CH2CH3
CH3CH2 N CH3 BF4 CH2CH3
T1173
T2375 CH3
CH2CH3 P H
T1507
CH3CH2
O
CH2CH3
CH3 BF4
CH3
O
Si C C
BF4
BF4 CH3
T1608
T2507
O
CH3
T1282
CH3 CH3
CH3
CH3
I
BF4 C
CH3
BF4
S
BF4
S
S
S
S
.
BF4
Bi
(BF4)2
3
CH3
T1121
BF4
Product No. Product Name A2065 A1861 B1151 B1658
4-Acetamido-2,2,6,6-tetramethyl-1-oxopiperidinium Tetrafluoroborate O-(7-Azabenzotriazol-1-yl)-N,N,N ',N '-tetramethyluronium Tetrafluoroborate 1,3-Benzodithiolylium Tetrafluoroborate [Hydroxyl-Protecting Agent] O-(Benzotriazol-1-yl)-N,N,N ',N '-tetramethyluronium Tetrafluoroborate
B2090
(S,S)-1,2-Bis[(tert-butyl)methylphosphino]ethane[η-(2,5-norbornadiene)]rhodium(I) Tetrafluoroborate Bis[η-(2,5-norbornadiene)]rhodium(I) Tetrafluoroborate 4-Bromobenzenediazonium Tetrafluoroborate 2-Bromo-1-ethylpyridinium Tetrafluoroborate 1-Butyl-2,3-dimethylimidazolium Tetrafluoroborate 1-Butyl-3-methylimidazolium Tetrafluoroborate 2-Chloro-3-ethylbenzoxazolium Tetrafluoroborate (3-Chloropropyl)diphenylsulfonium Tetrafluoroborate 1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium Tetrafluoroborate Copper(II) Tetrafluoroborate (ca. 45% in Water) 1-(Cyanomethyl)piperidinium Tetrafluoroborate Cyclopropyldiphenylsulfonium Tetrafluoroborate 1,3-Di(1-adamantyl)imidazolinium Tetrafluoroborate 1,3-Di(1-adamantyl)imidazolium Tetrafluoroborate 6,10-Dibenzyl-N,N '-dimethyl-N,N,N ',N '-tetrakis(4-methylbenzyl)-1,4-dioxaspiro[4.5]decane(2R,3R)-diylbis(methylammonium) Tetrafluoroborate [=(R,R)-TaDiAS-2nd] 6,10-Dibenzyl-N,N '-dimethyl-N,N,N ',N '-tetrakis(4-methylbenzyl)-1,4-dioxaspiro[4.5]decane(2S,3S)-diylbis(methylammonium) Tetrafluoroborate [=(S,S)-TaDiAS-2nd] 1,3-Di-tert-butylimidazolium Tetrafluoroborate 1,3-Diisopropylimidazolinium Tetrafluoroborate 1,3-Diisopropylimidazolium Tetrafluoroborate Dimethyl(methylthio)sulfonium Tetrafluoroborate Dimethylphenacylsulfonium Tetrafluoroborate Diphenyl(methyl)sulfonium Tetrafluoroborate 1-Ethyl-3-methylimidazolium Tetrafluoroborate [for Molten Salt] Ethynyl(phenyl)iodonium Tetrafluoroborate [Ethynylating Reagent]
[Coupling Reagent for Peptide]
B2091 B3114 B1036 B2475 B2195 C0905 C1380 C1375 C2410 C2421 C1390 D3620 D3621 D3475 D3476 D3711 D3622 D3623 D1945 D2231 D2685 E0496 E0467
370
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 1g
5g 5g 5g
5g
25g
100mg 5g 5g 5g 5g
50mg 1g 5g 25g 25g 25g 25g 1g 5g 500g 5g 1g 500mg 1g
200mg
1g
200mg
1g 5g 5g 1g 5g 5g 5g 25g 1g
1g 1g 1g 1g 5g
Classes of Boron Compounds
Product No. Product Name
Unit Size
F0358 F0344 F0334 F0343 F0346 H0734 H1099 L0133 N0137 N0634
N-Fluoro-N '-(chloromethyl)triethylenediamine Bis(tetrafluoroborate) 1-Fluoro-2,6-dichloropyridinium Tetrafluoroborate [Fluorinating Reagent] 1-Fluoropyridinium Pyridine Heptafluorodiborate [Fluorinating Reagent] 1-Fluoropyridinium Tetrafluoroborate [Fluorinating Reagent] 1-Fluoro-2,4,6-trimethylpyridinium Tetrafluoroborate [Fluorinating Reagent] Hexadecyltrimethylammonium Tetrafluoroborate 1-Hexyl-3-methylimidazolium Tetrafluoroborate Lithium Tetrafluoroborate 4-Nitrobenzenediazonium Tetrafluoroborate 2-(5-Norbornene-2,3-dicarboximido)-1,1,3,3-tetramethyluronium Tetrafluoroborate
O0195
μ-Oxo-bis[tris(dimethylamino)phosphonium] Bis(tetrafluoroborate) (=Bates' Reagent)
S0446 T0914 T2648 T2006 T0983 T1747 T2666 T0842 T2224 T2584 T2585 T2198 T1606 T1507 T2375 P1239 T1173 T1608 T2507 T1282 T1121
Silver Tetrafluoroborate Tetrabutylammonium Tetrafluoroborate Tetrabutylammonium Tetrafluoroborate Tetrabutylphosphonium Tetrafluoroborate Tetraethylammonium Tetrafluoroborate Tetraethylphosphonium Tetrafluoroborate Tetrakis(acetonitrile)copper(I) Tetrafluoroborate Tetramethylammonium Tetrafluoroborate N,N,N ',N '-Tetramethyl-O-(N-succinimidyl)uronium Tetrafluoroborate Tri-tert-butylphosphonium Tetrafluoroborate Tricyclohexylphosphonium Tetrafluoroborate Triethylmethylammonium Tetrafluoroborate Triethyloxonium Tetrafluoroborate (15% in Dichloromethane, ca. 1mol/L) [Ethylating Reagent] Trimethyloxonium Tetrafluoroborate 2,4,6-Trimethylpyrylium Tetrafluoroborate Trimethylsilylethynyl(phenyl)iodonium Tetrafluoroborate Triphenylmethylium Tetrafluoroborate Triphenylsulfonium Tetrafluoroborate Triphenyl-2,6-xylylbismuthonium Tetrafluoroborate Tris(tetrathiafulvalene) Bis(tetrafluoroborate) Complex Tropylium Tetrafluoroborate
5g 5g
25g 25g 5g 25g 5g 5g 25g 25g 25g
5g 1g 5g
5g
[Coupling Reagent for Peptide]
25g 1g 25g 500g 25g 25g 25g 25g 5g 500g 5g 5g 5g 25g 100ml 25g 25g 1g 25g 5g 1g 1g 5g
[for Peptide Synthesis]
P1480
P1807
5g 25g
5g 1g 25g 1g 1g 1g
5g 5g 5g 1g 100mg
P1814 BF3
CH2 CHCH2BF3
Trifluoroborates
K
K
BrCH2BF3 K CN
P1815
P1846 BF3
P1812
K
P1808 BF3
O
K
BF3
C H BF3
P1810 K OCH3
ICH2BF3 K
K
CN
P1580
P1820 BF3
K
OCH3
P1819 BF3
OCH3
K
P1582 BF3
K
NO2
P1717 BF3
K
BF3 N
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
K
371
Classes of Boron Compounds
P1684
P1828
P1818 BF3
K
BF3
P1583
P1692 BF3
K
K
CH3 S
BF3
CF3BF3 K
K
N
CH3
P1479
CH2 CHBF3
K
Product No. Product Name P1480 P1807 P1814 P1815 P1846 P1812 P1808 P1810 P1580 P1820 P1819 P1582 P1717 P1684 P1828 P1818 P1583 P1692 P1479
Unit Size
Potassium Allyltrifluoroborate Potassium (Bromomethyl)trifluoroborate Potassium (3-Cyanophenyl)trifluoroborate Potassium (4-Cyanophenyl)trifluoroborate Potassium Cyclopropyltrifluoroborate Potassium (2-Formylphenyl)trifluoroborate Potassium (Iodomethyl)trifluoroborate Potassium (2-Methoxyphenyl)trifluoroborate Potassium (3-Methoxyphenyl)trifluoroborate Potassium (4-Methoxyphenyl)trifluoroborate Potassium (3-Nitrophenyl)trifluoroborate Potassium Phenyltrifluoroborate Potassium 3-Pyridyltrifluoroborate Potassium 4-Pyridyltrifluoroborate Potassium 2-Thienyltrifluoroborate Potassium o-Tolyltrifluoroborate Potassium p-Tolyltrifluoroborate Potassium Trifluoro(trifluoromethyl)borate Potassium Vinyltrifluoroborate
1g 1g 1g
1g 1g 1g 1g 1g 5g 1g 1g 1g 1g 1g 5g 1g
1g
1g
B2132
C1669
D2130
O
Others
O
B
5g 5g 5g 5g 1g 1g 5g 5g 5g 5g 5g 25g 5g 5g 5g 5g 5g 25g 5g
O Br
O
B
Cl
N
O B CH3
D2131
S0558
T1085
OH B OH N
O
OH
B
. NaOH Na
B
CH3
Product No. Product Name B0516 B0517 B2132 C1669 D2130 D2131
372
Boraxcarmine powder Boraxcarmine Solution acc. to Grenacher B-Bromocatecholborane B-Chlorocatecholborane (R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine (S)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 100ml 5g 1g 1g
5g 500ml 5g 25g 5g 5g
Classes of Boron Compounds
Product No. Product Name S0558 T1085
Sodium (Trihydroxy)phenylborate Triphenyl Boron-Sodium Hydroxyde Adduct (7-9% in Water)
Unit Size 25g
5g 500g
Boron Trihalides Product No. Product Name B3556 X0032 X0033 X0034 B2074 B0527 X0035 B0894 X0036 X0037 E0399 P1096
Boron Trichloride (ca. 9% in Dichloromethane, ca. 1.0mol/L) Boron Trichloride - 2-Chloroethanol Reagent (5-10%) [for Esterification] Boron Trichloride - Methanol Reagent (5-10%) [for Esterification] Boron Trifluoride - Butanol Reagent (10-20%) [for Esterification] Boron Trifluoride - Butyl Ether Complex (BF3 ca. 30%) Boron Trifluoride - Ethyl Ether Complex Boron Trifluoride - Isopropyl Alcohol Reagent (10-20%) [for Esterification] Boron Trifluoride - Methanol Complex Boron Trifluoride - Methanol Reagent (10-20%) [for Esterification] Boron Trifluoride - Propanol Reagent (10-20%) [for Esterification] Ethylamine Trifluoroborane Piperidinium Trifluoroborate
Unit Size 100ml 1ml×10 1ml×10 1ml×10 25ml 500ml 25ml 500ml 1ml×10 100ml 500ml 1ml×10 1ml×10 25g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
373
Metallocenes
Metallocenes
A0775
A1601
A0766 CH3
O
NH2
C CH3
Ferrocenes
B0886
B2711
B2710
O
C(CH3)3 C(CH3)3
Fe
Fe
P
B3374
Fe P
C(CH3)3
B2226 Ph P Ph NiCl2 P Ph
Fe
Ph
B0885
Fe
PPh2
PPh2
Fe
Fe
PPh2
CH(CH3)2
Ph P Ph PdCl2. CH2Cl2 P Ph
Fe
B3476 CH3 CH3
O B O Fe
O B O
Ph
B2063
CH3 CH3
Br Fe
CH3 CH3 CH3 CH3
F0312
F0313
CH3
O
(CH2)3CH3
NH C OC(CH3)3
C CH3
Fe
Fe
B0913
B0915
D2829 O
C CH3
C
C CH3
C O
D2951 O (CH2)3CH3
C CH2CH2CH3 Fe
Fe Br
C CH2CH2CH3
(CH2)3CH3
O
D2537
D2538
D2535
CH3 CH2N
Fe
Br Fe
O
Fe
D1272
Fe
D1271
CH3
Fe
O
Fe
D2536
CH3
CH3
CH3
CH3 N(CH3)2 PPh2
CH3
Fe
(CH3)2N Ph2P
Fe
D1273
N(CH3)2 PPh2 Fe
D2528
D2529 CH3
Fe
E0394
CH3 N
Fe CH3
Fe
D3822
CH3 Fe
N(CH3)2
(CH3)2N Ph2P
Ph2P
PPh2
374
Ph2P
CH(CH3)2 CH(CH3)2
B3501
Ph
B2227
B2027
CH(CH3)2
B2064
Ph P Ph CoCl2 P Ph
Fe
P
CH3
Fe
B3196
C(CH3)3
P
C
C CH2CH3
Fe
Fe
Fe
N(CH3)2
CH
CH3 CH2CH3
CH3
Fe PPh2 O
Availability, price or specification of the listed products are subject to change without prior notice.
Fe
Metallocenes
D0444
F0406
F0280
F0165
F0664
O CH2 Fe
O B(OH)2
C OH
B0914
F0320 O
C OH
C
Fe
Fe
Fe
F0286
O
B(OH)2
F0166
O
F0167 CH3
CH3
CH2CH2 C OH
CH2 N
CH2
(CH2)11CH3
CH3
Fe
Fe
B(OH)2
C OH
Fe
Fe
Br
CH3
Fe
CH3
N CH3
C OH
Br
CH2 N CH3 CH3
Fe
I
O
H0941
H0463
H0464
O
OH
C NHNH2
CHCH3
Fe
T2546 O S
Fe
Fe
B3501 B3476 B2227 B0885 B2063 F0312 F0313 B0913 B0915 D2829 D1272 D2951 D1271 D2537 D2538 D2535 D2536 D1273 D2528 D2529 D3822
CH
O
CH3 O
CH3
C O N Fe
O
Fe
O
V0064 O
CH3
S Fe
CH
CH3
CH2
Fe
Product No. Product Name A0775 A1601 A0766 B0886 B2711 B2710 B3196 B2027 B3374 B2226 B2064
S0820 N
CH2OH
Fe
T2545
I0749
Acetylferrocene Aminoferrocene tert-Amylferrocene Benzoylferrocene 1,1'-Bis(di-tert-butylphosphino)ferrocene 1,1'-Bis(diisopropylphosphino)ferrocene (R,R '')-2,2''-Bis(diphenylphosphino)-1,1''-biferrocene 1,1'-Bis(diphenylphosphino)ferrocene [1,1'-Bis(diphenylphosphino)ferrocene]cobalt(II) Dichloride [1,1'-Bis(diphenylphosphino)ferrocene]nickel(II) Dichloride [1,1'-Bis(diphenylphosphino)ferrocene]palladium(II) Dichloride Dichloromethane Adduct 1,1'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ferrocene Bromoferrocene N-(tert-Butoxycarbonyl)aminoferrocene Butylferrocene tert-Butylferrocene Cyclohexenylferrocene Cyclopentenylferrocene 1,1'-Diacetylferrocene 1,1'-Dibenzoylferrocene 1,1'-Dibromoferrocene 1,1'-Dibutylferrocene 1,1'-Dibutyrylferrocene N,N-Dimethylaminomethylferrocene (R)-N,N-Dimethyl-1-[(S)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine (S)-N,N-Dimethyl-1-[(R)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine (R)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine (S)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine 1,1'-Dimethylferrocene (R)-(+)-N,N-Dimethyl-1-ferrocenylethylamine (S)-(-)-N,N-Dimethyl-1-ferrocenylethylamine (S)-1-(Diphenylphosphino)-2-[(S)-4-isopropyloxazolin-2-yl]ferrocene
Unit Size 10g 100mg 5g 100mg 100mg 100mg 1g 5g 1g 1g 1g
5g 1g 1g 10g 1g
5g 1g 1g 5g 5g
5g 200mg 200mg 200mg
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 1g 1g 25g 1g 1g 500mg 25g 5g 5g 25g 5g 5g 1g 25g 5g 25g 25g 5g 25g 5g 5g 25g 25g 100mg 100mg 100mg 100mg 25g 1g 1g 1g
375
Metallocenes
Product No. Product Name
Unit Size
E0394 D0444 F0406 F0280
Ethylferrocene Ferrocene Ferroceneacetic Acid Ferroceneboronic Acid (contains varying amounts of Anhydride) [Cyclic boronating reagent
F0165 F0664 B0914 F0320 F0286 F0166 F0167 H0941 H0463 H0464 I0749 S0820 T2545 T2546 V0064
Ferrocenecarboxylic Acid 1,1'-Ferrocenediboronic Acid (contains varying amounts of Anhydride) 1,1'-Ferrocenedicarboxylic Acid 3-Ferrocenoylpropionic Acid (Ferrocenylmethyl)dodecyldimethylammonium Bromide (Ferrocenylmethyl)trimethylammonium Bromide (Ferrocenylmethyl)trimethylammonium Iodide (Hydrazinocarbonyl)ferrocene [for HPLC Labeling] 1-Hydroxyethylferrocene Hydroxymethylferrocene (S)-(4-Isopropyloxazolin-2-yl)ferrocene N-Succinimidyl Ferrocenecarboxylate (R)-(p-Toluenesulfinyl)ferrocene (S)-(p-Toluenesulfinyl)ferrocene Vinylferrocene
100mg 5g
for GC/MS]
B1951
5g 500g 5g
25g 1g 1g
1g 25g 1g 5g 25g 5g 5g 5g 1g 5g 5g 5g 1g 5g 5g 1g
1g
1g
1g 1g 1g 200mg 1g 1g
C1589
D3307 CH3 CH3 CH3
Fe
Others
Co
PF6
PF6
CH3 CH3
Cl CH3 CH3
Zr Cl CH3 CH3 CH3
D3321
D3956
D3286
H0914
(CH2)3CH3 Cl
Zr
CH2CH2CH3 CH3
Cl
Ti
Cl
CH3
Hf
C1411
Ru
Ni
V Cl
Hf
Cl
CH3
CF3SO3
T1658
Ti
Z0009
Cl
Cl CH2CH2CH3
R0078
V0090
CH3
Cl
(CH2)3CH3
D1574
I0645
Cl
Al
CH3 CH3
Z0010
Zr SO3CF3
.
C
Zr
Cl Cl
T0616
O
O
F3C S O Ti
O S CF3
O
Cl
Ti
Cl
O
Z0007
H
Zr
Cl
Cl
Zr
Cl
O
Product No. Product Name B1951 C1589 D3307 D3321 D3956 D3286
376
η-Benzene(η-cyclopentadienyl)iron(II) Hexafluorophosphate Bis(cyclopentadienyl)cobalt(III) Hexafluorophosphate Decamethylzirconocene Dichloride 1,1'-Dibutylzirconocene Dichloride Dimethyltitanocene (5% in Toluene) 1,1'-Dipropylhafnocene Dichloride
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 1g
1g
5g 1g 1g 5g 100g 1g
Metallocenes
Product No. Product Name H0914 I0645 D1574 R0078 C1411 T1658 T0616 V0090 Z0009 Z0010 Z0007
Unit Size
Hafnocene Dichloride 1,1'-Isopropylidenezirconocene Dichloride Nickelocene Ruthenocene Tebbe Reagent (ca. 0.5mol/L in Toluene) Titanocene Bis(trifluoromethanesulfonate) Titanocene Dichloride Vanadinocene Dichloride Zirconocene Bis(trifluoromethanesulfonate) Tetrahydrofuran Adduct Zirconocene Chloride Hydride Zirconocene Dichloride
C2201
I0646
Cl
5g 1g
100mg 5g 1g 5g 5g
1g
C1994
Ph3P Ru PPh3
Half Metallocenes
1g
25g 100mg 5g 1g 25ml 1g 25g 1g 5g 25g 25g
C1995
Cl
Ti Cl
Cl
Cl
Zr
Cl
Cl
P1651 CH3 CH3 Cl
Ti
Cl
Cl
CH3 CH3 Ti CH3 Cl3
Product No. Product Name C2201 C1994 C1995 I0646 P1651
Cyclopentadienylbis(triphenylphosphine)ruthenium(II) Chloride Cyclopentadienyltitanium(IV) Trichloride Cyclopentadienylzirconium(IV) Trichloride (Indenyl)titanium(IV) Trichloride (Pentamethylcyclopentadienyl)titanium(IV) Trichloride
Unit Size 1g 1g 1g
5g 5g 5g 1g 1g
References 1) Basic trends in the practical use of ferrocene and its derivatives 1974, A. N. Nesmeyanov, N. S. Kochetkova, , 710. 2) Ferrocene polymers - a new raw material 1976, N. Tanaka, , 61. 3) Biologically active derivatives of ferrocene 1988, S. Kaluz, S. Toma, , 529. 4) Industrial uses of dicyclopentadienylmetal complexes 1975, H. Arai, , 88.
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
377
Classes of Metal Compounds
Classes of Metal Compounds Typical Metal Compounds Li, Na, K, Rb, Be, Mg, Ca, Ba, Al, In, Tl, Sn, Pb Transition Metal Compounds Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Y, Zr, Mo, Ru, Rh, Pd, Ag, Cd, La, Ce, Pr, Nd, Sm, Eu, Tm, Yb, Hf, W, Re, Os, Ir, Pt, Au, Hg Semimetal Compounds B (see. p.357), Si (see. p.162), Ge, As, Se, Sb, Te, Bi
Typical Metal Compounds Li (Lithium) Product No. Product Name B0396 B2651 H0842 L0060 L0061 L0191 A1478 L0170 L0203 B2542 L0186 L0210 L0224 L0204 L0222 L0171 F0171 L0146 H1057 H0915 L0225 H0580 L0144 P0659 S0237 L0133 L0158 L0159 L0164 T1548 M1655 L0080 P1429 P1049 S0384
Butyllithium (ca. 15% in Hexane, ca. 1.6mol/L) tert-Butyllithium (ca. 16% in Pentane, ca. 1.6mol/L) Hexyllithium (30% in Hexane, ca. 2.3mol/L) Lithioncarmine (powder) Lithioncarmine Solution acc. to Orth Lithium Acetate Lithium Acetoacetate Lithium Aluminum Hydride (10% in Tetrahydrofuran, ca. 2.5mol/L) Lithium Aluminum Hydride (Powder) Lithium Bis(trifluoromethanesulfonyl)imide Lithium Borohydride (ca. 3mol/L in Tetrahydrofuran) Lithium Bromide [for General Organic Chemistry] Lithium Carbonate [for General Organic Chemistry] Lithium Chloride Anhydrous Lithium Chloride (2.3% in Tetrahydrofuran, ca. 0.5mol/L) Lithium Diisopropylamide (25% in Tetrahydrofuran/Ethylbenzene/Heptane, ca. 2mol/L) Lithium Formate Monohydrate Lithium Hexafluorophosphate Lithium 1,1,2,2,3,3-Hexafluoropropane-1,3-disulfonimide Lithium Hexamethyldisilazide (29% in Tetrahydrofuran, ca. 1.6mol/L) Lithium Hydroxide Anhydrous [for General Organic Chemistry] Lithium DL-2-Hydroxybutyrate Lithium L-Lactate Lithium Pyruvate Monohydrate [Guaranteed for Standard to GOT, GPT] Lithium Stearate Lithium Tetrafluoroborate Lithium Tetrakis(pentafluorophenyl)borate - Ethyl Ether Complex Lithium Tri-tert-butoxyaluminum Hydride (20% in Tetrahydrofuran, ca. 0.7mol/L) Lithium Tri-sec-butylborohydride (21% in Tetrahydrofuran, ca. 1.0mol/L) Lithium Trifluoromethanesulfonate Methyllithium (ca. 3% in Ethyl Ether, ca. 1mol/L) (2,4-Pentanedionato)lithium Phenyllithium (ca. 16% in Butyl Ether, ca. 1.6mol/L) Phthalocyanine Dilithium Salicylic Acid Lithium Salt
Unit Size 100ml
25g 1g 25g 25g 25g 25g 25g
25g 1g 100ml 25g 5g
25g 1g
25g
25g
500ml 100ml 100ml 1g 500ml 500g 5g 100ml 100g 250g 100ml 500g 500g 300g 100ml 100ml 500g 25g 5g 500ml 500g 25g 25g 25g 500g 25g 5g 100ml 100ml 25g 100ml 500g 100ml 1g 500g
Na (Sodium) (excluding simple sodium salts) Product No. Product Name C0075 C0076 C1374 D1331 D0923 D1930
378
Chloramine B Chloramine T Trihydrate o-Chloramine T 5,5-Diphenylhydantoin Sodium Salt Dipicrylamine Sodium Salt (contains 10% Water) Disodium Dimercaptomaleonitrile
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 25g 25g 25g 1g
500g 500g 25g 500g 1g 5g
Classes of Metal Compounds
Product No. Product Name
Unit Size
M0632 M0096 S0489 S0480 S0396 D1003 D2479 D0716 S0548 S0547 E0195 S0392 H0894 S0481 M0057 S0485 S0486 P0973 S0540 A5131
2-Mercaptopyridine N-Oxide Sodium Salt (40% in Water, ca. 3.3mol/L) Methyl Mercaptan Sodium Salt (ca. 15% in Water) Sodium Azide Sodium Borohydride Sodium Cyanoborohydride [Reducing Agent] Sodium Dichloroisocyanurate Sodium Diformylamide Sodium Dimethyldithiocarbamate Dihydrate Sodium Ethoxide (ca. 20% in Ethanol) Sodium Ethoxide Sodium Ethylxanthate Sodium Hexafluorophosphate Sodium Hexamethyldisilazide (contains 2-Methyl-2-butene) (38% in Tetrahydrofuran, ca. 1.9mol/L) Sodium Hydride (60%, dispersion in Paraffin Liquid) Sodium 2-Mercaptobenzothiazole Sodium Methoxide Sodium Methoxide (ca. 5mol/L in Methanol) Sodium Phthalocyanine Sodium Tetrachloropalladate(II) Sodium Tetrakis(4-fluorophenyl)borate Hydrate [Precipitation reagent for Cs and titrimetric reagent
A5130 T0193 S0394 B0131
Sodium Tetraphenylborate [Precipitation reagent for K] Sodium 2-Thiobarbiturate Sodium Triacetoxyborohydride o-Sulfobenzimide Sodium Salt Dihydrate
25g 25g 100g 25g 25g 25g
25g 100ml 25g 100g 1g 1g 1g 25g 25g 25g
for nonionic surfactants]
500g 500g 100g 500g 250g 500g 25g 500g 500ml 100g 500g 25g 500ml 100g 500g 500g 500ml 5g 1g 5g 10g 500g 100g 500g
K (Potassium) (excluding simple potassium salts) Product No. Product Name A1490 B1124 C0714 I0223 I0019 I0220 N0428 P0097 P0179 P0403 P1480 P1681 P1807 P1008 B0747 P1613 E0194 G0160 H0817 H1058 H0893 H0652 P0309 I0023 P1808 I0177 N0006 O0056 O0164 P0534 R0058 S0057 S0164 A5132 P1380 P1692 P0475 P1479 P0988 P0989
Acesulfame K Bismuthiol II Hydrate Carbazole Potassium Salt Indigodisulfonic Acid Dipotassium Salt Indigotetrasulfonic Acid Tetrapotassium Salt Hydrate Indigotrisulfonic Acid Potassium Salt 4-Nitrocatechol Sulfate Dipotassium Salt [Substrate for Sulfatase] Phenolphthalein Disulfate Potassium Salt Hydrate N-Phenylglycine Potassium Salt Phthalimide Potassium Salt Potassium Allyltrifluoroborate Potassium Borohydride Potassium (Bromomethyl)trifluoroborate Potassium tert-Butoxide Potassium Butylxanthate Potassium Cyanide Potassium Ethylxanthate Potassium Guaiacolsulfonate Hemihydrate Potassium Hexafluoroarsenate Potassium 1,1,2,2,3,3-Hexafluoropropane-1,3-disulfonimide Potassium Hexamethyldisilazide (11% in Toluene, ca. 0.5mol/L) Potassium Hyaluronate from Cockscomb Potassium Hydrogen Phthalate Potassium 3-Indoleacetate Potassium (Iodomethyl)trifluoroborate Potassium Isopropylxanthate Potassium 1-Naphthaleneacetate Potassium Oleate Potassium Oxonate Potassium Propylxanthate Potassium Rhodizonate Potassium Sorbate Potassium Sulfamate Potassium Tetrakis(4-chlorophenyl)borate [Anion for the neutral carrier type ion electrode] Potassium Tri-sec-butylborohydride (ca. 1.0mol/L in Tetrahydrofuran) Potassium Trifluoro(trifluoromethyl)borate Potassium Trihydrogen Dioxalate Dihydrate [for Determination of pH] Potassium Vinyltrifluoroborate Pyridoxylidene-L-glutamic Acid Dipotassium Salt Pyridoxylidene-L-isoleucine Potassium Salt
Unit Size 25g 5g
1g 1g 25g 25g 1g
25g
1g 100g 25g 25g 25g 1g 100ml 25g 1g 1g
25g 5g
25g 1g 1g
5g 25g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500g 25g 25g 1g 1g 5g 1g 5g 500g 500g 5g 100g 5g 500g 500g 25g 500g 500g 10g 5g 500ml 1g 500g 25g 5g 25g 25g 500g 25g 25g 1g 500g 100g 5g 100ml 25g 500g 5g 1g 1g
379
Classes of Metal Compounds
Product No. Product Name S0156 A5107
Sinigrin Hydrate TBPE (=Tetrabromophenolphthalein Ethyl Ester Potassium Salt) [Sensitive spectrophotometric
T1083 T0036 F0027
Terephthalic Acid Monomethyl Ester Potassium Salt Tetrabromofluorescein Potassium Salt Uranine K
Unit Size 100mg
reagent for amines, quaternary ammonium salts and other cations]
25g
1g 500g 25g 25g
Rb (Rubidium) Product No. Product Name F0172
Unit Size
Formic Acid Rubidium Salt
5g
Be (Beryllium) Product No. Product Name B0454
Unit Size
Bis(2,4-pentanedionato)beryllium(II)
5g
Mg (Magnesium) Product No. Product Name A0963 A1554 A0484 A5353 B1883 B1933 M0001 T0749 B1884 B0726 B1147 B1148 C0780 C1504 C1505 D3551 E0287 E0396 E0094 E0134 E0497 E0135 E0778 H0822 H0821 I0517 I0518 I0542 I0543 I0654
Allylmagnesium Bromide (ca. 13% in Ethyl Ether, ca. 0.7mol/L) Allylmagnesium Chloride (ca. 9% in Tetrahydrofuran, ca. 0.8mol/L) 8-Anilino-1-naphthalenesulfonic Acid Magnesium(II) Salt Hydrate ANS-Mg (=Magnesium 8-Anilino-1-naphthalenesulfonate) [Hydrophobic fluorescent probe] Benzylmagnesium Bromide (ca. 12% in Tetrahydrofuran, ca. 0.6mol/L) Benzylmagnesium Chloride (ca. 16% in Tetrahydrofuran, ca. 1mol/L) Bis(2,4-pentanedionato)magnesium(II) Bis(trifluoro-2,4-pentanedionato)magnesium(II) sec-Butylmagnesium Bromide (16% in Tetrahydrofuran, ca. 1mol/L) Butylmagnesium Chloride (23% in Tetrahydrofuran, ca. 2mol/L) tert-Butylmagnesium Chloride (26% in Ethyl Ether, ca. 2mol/L) tert-Butylmagnesium Chloride (23% in Tetrahydrofuran, ca. 2mol/L) Chlorophyll (Total Chlorophyll: ca. 0.5%) Cyclohexylmagnesium Bromide (ca. 17% in Tetrahydrofuran, ca. 1mol/L) Cyclopentylmagnesium Bromide (18% in Tetrahydrofuran, ca. 1mol/L) (2,5-Dimethylphenyl)magnesium Bromide (20% in Tetrahydrofuran, ca. 1mol/L) 1,2-Ethanedisulfonic Acid Magnesium Salt 2-Ethylbutyric Acid Magnesium Salt Ethylenediaminetetraacetic Acid Disodium Magnesium Salt Hydrate Ethylmagnesium Bromide (39% in Ethyl Ether, ca. 3mol/L) Ethylmagnesium Bromide (13% in Tetrahydrofuran, ca. 1mol/L) Ethylmagnesium Chloride (18% in Tetrahydrofuran, ca. 2mol/L) Ethylmagnesium Chloride (ca. 1.0mol/L in Tetrahydrofuran) activated with Zinc Chloride (ca. 10mol%) Heptylmagnesium Bromide (21% in Tetrahydrofuran, ca. 1mol/L) Hexylmagnesium Bromide (20% in Tetrahydrofuran, ca. 1mol/L) Isobutylmagnesium Bromide (17% in Tetrahydrofuran, ca. 1mol/L) Isopropylmagnesium Bromide (15% in Tetrahydrofuran, ca. 1mol/L) Isopropylmagnesium Chloride (13% in Ethyl Ether, ca. 1mol/L) Isopropylmagnesium Chloride (ca. 11% in Tetrahydrofuran, ca. 1mol/L) Isopropylmagnesium Chloride - Lithium Chloride (15% in Tetrahydrofuran, ca. 1mol/L)
G0276 H0556 M0938 P1018 T1304 M0785 M0362 M0364 M0927 O0240 P1251 P1177 P0108 P0190 P1381 P0191 P0880 T1698
Magnesium(II) Gluconate Hydrate Magnesium(II) Hexafluoroacetylacetonate Hydrate Magnesium 4-Nitrobenzyl Malonate Hydrate Magnesium(II) Phthalocyanine Magnesium Trifluoromethanesulfonate Methylmagnesium Bromide (35% in Ethyl Ether, ca. 3mol/L) Methylmagnesium Bromide (12% in Tetrahydrofuran, ca. 1mol/L) Methylmagnesium Iodide (33% in Ethyl Ether, ca. 2mol/L) Monoperoxyphthalic Acid Magnesium Salt Hexahydrate n-Octylmagnesium Bromide (ca. 22% in Tetrahydrofuran, ca. 1mol/L) Pentadecylmagnesium Bromide (17% in Tetrahydrofuran, ca. 0.5mol/L) Pentylmagnesium Bromide (18% in Tetrahydrofuran, ca. 1mol/L) Phenoxyacetic Acid Magnesium Salt Phenylmagnesium Bromide (32% in Tetrahydrofuran, ca. 2mol/L) Phenylmagnesium Chloride (27% in Tetrahydrofuran, ca. 2mol/L) Phenylmagnesium Iodide (42% in Ethyl Ether, ca. 2mol/L) Propylmagnesium Bromide (ca. 27% in Tetrahydrofuran, ca. 2mol/L) o-Tolylmagnesium Bromide (19% in Tetrahydrofuran, ca. 1mol/L)
Unit Size 100ml 100g 25g 1g 100g 250g 25g 5g 100g 250g 250g 250g 25g 100g 100g 100g 5g 25g 25g 250g 250g 250g 250g 250g 250g 250g 250g 250g 250g
(This product is only available for selling domestically in Japan.)
380
Availability, price or specification of the listed products are subject to change without prior notice.
25g
5g
25g
100ml 500g 1g 25g 1g 25g 250g 250g 100g 500g 250g 250g 250g 25g 250g 250g 250g 250g 100g
Classes of Metal Compounds
Product No. Product Name T1699 T1700 T1451 V0053
Unit Size
m-Tolylmagnesium Bromide (19% in Tetrahydrofuran, ca. 1mol/L) p-Tolylmagnesium Bromide (19% in Tetrahydrofuran, ca. 1mol/L) Trimethylsilylmethylmagnesium Chloride (20% in Ethyl Ether, ca. 1mol/L) Vinylmagnesium Bromide (14% in Tetrahydrofuran, ca. 1mol/L)
100g 100g 100ml 100g
Ca (Calcium) Product No. Product Name A0422 C0930 A0738 G0037 G0232 G0095 H0651 L0043 O0076 M0549 K0021 K0022 K0023 P1237 P0012 C2003 P0503 S0054 S0236 T0002 T0004 T0902 T1799 C0849 D1869 E0088 F0372 G0200 H0917 L0006 L0075 M0548 P0274 P0410
Unit Size
4-Aminosalicylic Acid Calcium Salt Heptahydrate Bis(2,4-pentanedionato)calcium(II) Calcium Alginate Calcium Gluconate Monohydrate Calcium DL-Glycerate Hydrate Calcium Glycerophosphate Hydrate Calcium 2-Hydroxy-4-(methylthio)butyrate Calcium Levulinate Dihydrate Calcium Mesoxalate Trihydrate Calcium Methanesulfonate Calcium 3-Methyl-2-oxobutyrate Hydrate Calcium 3-Methyl-2-oxovalerate Hydrate Calcium 4-Methyl-2-oxovalerate Hydrate Calcium DL-Pantothenate Calcium D-Pantothenate Calcium Phthalate Hydrate Calcium Propionate Calcium Sorbate Calcium Stearate Calcium DL-Tartrate Tetrahydrate Calcium meso-Tartrate Trihydrate Calcium Thioglycolate Trihydrate Calcium L-Threonate 4-Chlorobenzoyl-L-tryptophan Calcium Salt Diethylenetriaminepentaacetic Acid Calcium Trisodium Salt Hydrate Ethylenediaminetetraacetic Acid Calcium Disodium Salt Hydrate Fenoprofen Calcium Salt Dihydrate Glycolic Acid Calcium Salt 3-Hydroxy-3-methylbutyric Acid Calcium Salt Monohydrate Lactobionic Acid Calcium Salt Lithol Rubin BCA Methacrylic Acid Calcium Salt Hydrate Phosphocholine Chloride Calcium Salt Tetrahydrate Phytin
25g 25g 25g 25g 25g
25g 5g 5g 25g 5g 25g 25g 1g 25g
25g
25g 25g
500g 250g 500g 500g 10g 500g 25g 25g 5g 500g 5g 25g 25g 25g 500g 25g 500g 25g 500g 25g 25g 500g 25g 25g 25g 500g 25g 25g 25g 25g 25g 500g 25g 500g
Ba (Barium) Product No. Product Name A0760 C0078 C0978 D0876 E0085 S0235 F0063 G0052 I0039 L0074 M0046 P0257 P0258 R0026
Barium Acrylate Monomer Barium Chloranilate Trihydrate Barium 2-Cyanoethylphosphate Hydrate [Phosphorylating Agent] Barium Diphenylamine-4-sulfonate Barium Disodium Ethylenediaminetetraacetate Hydrate Barium Stearate Fructose-1-phosphate Barium Salt Trihydrate D-Glucose-6-phosphate Barium Salt Inosine 5'-Monophosphate Barium Salt Hydrate Lake Red CBA Mannose-6-phosphate Barium Salt Hydrate 6-Phosphogluconate Barium Salt Hydrate 3-Phospho-D-glyceric Acid Barium Salt Dihydrate Ribose-5-phosphate Barium Salt Hydrate
Unit Size
1g
5g 5g 25g 100mg
100mg
25g 25g 25g 25g 25g 500g 100mg 1g 100mg 25g 100mg 100mg 1g 1g
Al (Aluminum) Product No. Product Name A0244 A0804 A1831 A0245
Aluminum sec-Butoxide Aluminum tert-Butoxide Aluminum(III) Chloride Aluminum Ethoxide
Unit Size 25g 5g 25g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
500g 25g 100g 250g
381
Classes of Metal Compounds
Product No. Product Name
Unit Size
A1200 A0246 B1895 D1340 D2971 D2972 E0648 L0170 L0203 L0159 M1211 M0468 M0469 C1167 S0467 C1411 T1086 T0783 T0925 T1330 T0784 T0782 T1575 A0241 T1527 T2238 A1267
25g 100g 25g
Aluminum Glycinate Aluminum Isopropoxide Bis(2-ethylhexanoato)hydroxyaluminum Diethylaluminum Chloride (ca. 15% in Hexane, ca. 0.87mol/L) Diisobutylaluminum Hydride (19% in Hexane, ca. 1.0mol/L) Diisobutylaluminum Hydride (17% in Toluene, ca. 1.0mol/L) Ethylaluminum Dichloride (17% in Hexane, ca. 1mol/L) Lithium Aluminum Hydride (10% in Tetrahydrofuran, ca. 2.5mol/L) Lithium Aluminum Hydride (Powder) Lithium Tri-tert-butoxyaluminum Hydride (20% in Tetrahydrofuran, ca. 0.7mol/L) Methylaluminum Bis(2,6-di-tert-butyl-4-methylphenoxide) (0.4mol/L in Toluene) Mucicarmine Mucicarmine Solution acc. to Mayer Phthalocyanine Chloroaluminum Sodium Bis(2-methoxyethoxy)aluminum Dihydride (70% in Toluene, ca. 3.6mol/L) Tebbe Reagent (ca. 0.5mol/L in Toluene) Triethylaluminum (15% in Benzene, ca. 1.1mol/L) Triethylaluminum (15% in Hexane, ca. 1.0mol/L) Triethylaluminum (15% in Toluene, ca. 1.1mol/L) Triisobutylaluminum (15% in Heptane, ca. 0.53mol/L) Triisobutylaluminum (15% in Hexane, ca. 0.50mol/L) Trimethylaluminum (15% in Hexane, ca. 1.4mol/L) Trimethylaluminum (15% in Toluene, ca. 1.8mol/L) Tris(2,4-pentanedionato)aluminum(III) Tris(8-quinolinolato)aluminum Tris(8-quinolinolato)aluminum (purified by sublimation) Tris(trifluoro-2,4-pentanedionato)aluminum(III)
100ml 100ml
25g
25g
25g 25g 5g
500g 500g 250g 100ml 500ml 500ml 100ml 100ml 100g 100ml 50ml 25g 500ml 1g 500g 25ml 100ml 100ml 100ml 100ml 100ml 100ml 100ml 500g 250g 5g 25g
In (Indium) Product No. Product Name I0778 I0020
Indium(III) Chloride Anhydrous [for General Organic Chemistry] Tris(2,4-pentanedionato)indium(III)
Unit Size 5g
25g 10g
Tl (Thallium) Product No. Product Name C0954 T1351
Unit Size
Cyclopentadienyl Thallium Thallium(III) Trifluoroacetate
5g 10g
Sn (Tin) Product No. Product Name A2170 A1222 A1491 T0650 B1974 B1975 B0907 B1832 D2466 D0302 D0223 D0303 D0304 B0355 D0305 D1338 D1373 D2358 M1494 M0744 P1282 P0997 T2009 T1592 T0058 T0919
382
Allenyltributyltin Allyltributyltin Allyltriphenyltin Bis(2,4-pentanedionato)tin(IV) Dichloride Bis(tributylstannyl)acetylene trans-1,2-Bis(tributylstannyl)ethylene Bis(tributylstannyl) Sulfide Bis(tributyltin) Dibutyltin Bis(trifluoromethanesulfonate) Dibutyltin Diacetate Dibutyltin Dichloride Dibutyltin Dilaurate Dibutyltin Maleate (so called) [for PVC stabilizer] Dibutyltin Maleate Polymer n=2-3 Dibutyltin Oxide Dimethyltin Dichloride Di-n-octyltin Oxide Diphenyltin Sulfide [Activator for O-Glycoside Synthesis] Methyl Tributylstannyl Sulfide Monobutyltin Oxide Phenyltin Trichloride Phthalocyanine Tin(IV) Dichloride Tetraallyltin Tetrabutylammonium Difluorotriphenylstannate Tetrabutyltin Tetramethyltin Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 1g 5g 5g 1g 1g 1g 5g 25g 25g 25g 25g 25g 25g 25g 25g 1g 25g 25g 5g 1g 1g 25g 5g
5g 25g 25g 25g 5g 5g 5g 25g 5g 500g 500g 500g 500g 500g 500g 500g 500g 5g 100g 500g 25g 1g 5g 5g 500g 25g
Classes of Metal Compounds
Product No. Product Name T0165 T2053 P1024 T1194 T1750 T1797 T1736 T1798 T0677 T0363 T0678 T1473 T1865 T1866 T1794 T1742 T1928 T0958 T1572 T0447 T0922
Tetraphenyltin Tin(IV) Chloride (ca. 1.0mol/L in Dichloromethane) Tin(II) Phthalocyanine Tin(II) Trifluoromethanesulfonate Tributylethynyltin Tributyl(2-furyl)tin Tributyl(2-pyridyl)tin Tributyl(2-thienyl)tin Tributyltin Acetate Tributyltin Chloride Tributyltin Fluoride Tributyltin Hydride (stabilized with BHT) [Reducing Reagent] Tributyl(trimethylsilylethynyl)tin Tributyl(trimethylsilylmethyl)tin Tributylvinyltin Trimethyl(2-pyridyl)tin Trimethyl(4-pyridyl)tin Trimethyltin Chloride Tri-n-octyltin Hydride [Reducing Reagent] Triphenyltin Chloride Triphenyltin Hydroxide
Unit Size 25g
1g
1g
1g 5g 1g 5g 5g 25g 25g 5g
1g
5g 1g 1g 5g
500g 100ml 5g 25g 5g 5g 25g 25g 25g 500g 25g 250g 25g 5g 25g 5g 5g 25g 10g 5g 5g
Pb (Lead) Product No. Product Name E0093 L0021 N0339 P0766 T0164
Ethylenediaminetetraacetic Acid Disodium Lead Salt Hydrate Lead Tetraacetate (contains Acetic Acid) Naphthenic Acid Lead Salt Phthalocyanine Lead Tetraphenyl Lead
Unit Size 25g 25g 25g 1g
500g 500g 500g 25g 5g
Transition Metal Compounds Sc (Scandium) Product No. Product Name S0534 T1663
Scandium(III) Acetate Hydrate Scandium(III) Trifluoromethanesulfonate
Unit Size 1g 1g
5g 5g
Ti (Titanium) Product No. Product Name B1588 B3395 T0249 B0855 C1994 D2257 D3956 I0646 A5020
[1,2-Benzenediolato(2-)-O,O ']oxotitanium Bis(2,4-pentanedionato)bis(2-propanolato)titanium(IV) (75% in Isopropyl Alcohol) Bis(2,4-pentanedionato)titanium(IV) Oxide Bis[tris(acetylacetonate)titanium(IV)] Hexachlorotitanate(IV) Cyclopentadienyltitanium(IV) Trichloride Dichlorotitanium Diisopropoxide Dimethyltitanocene (5% in Toluene) (Indenyl)titanium(IV) Trichloride Oxo[5,10,15,20-tetra(4-pyridyl)porphyrinato]titanium(IV) [Determination of Glucose in Serum and
P1651 C1411 B0742 B0743 T0967 T0978 T0133 T2230 T2610 T0666 T2052 T1658 T0616
(Pentamethylcyclopentadienyl)titanium(IV) Trichloride Tebbe Reagent (ca. 0.5mol/L in Toluene) Tetrabutyl Orthotitanate Tetrabutyl Orthotitanate Tetramer Tetraethyl Orthotitanate Tetraisobutyl Orthotitanate (contains Isopropoxide) Tetraisopropyl Orthotitanate Tetrakis(dimethylamino)titanium(IV) Tetrakis(2,4-pentanedionato)titanium(IV) (ca. 63% in Isopropyl Alcohol) Tetraoctadecyl Orthotitanate Titanium(IV) Chloride (14% in Dichloromethane, ca. 1.0mol/L) Titanocene Bis(trifluoromethanesulfonate) Titanocene Dichloride
Unit Size 25g 25g 1g 5g
Urine]
25g 25g 25ml 25g 1g 25g 25g 100mg 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
1g 500g 500g 25g 5g 25g 100g 1g 100mg 1g 25ml 500g 500g 500ml 25ml 500g 5g 500g 500g 100ml 1g 25g
383
Classes of Metal Compounds
V (Vanadium) Product No. Product Name V0016 T2548 V0090
Unit Size
Bis(2,4-pentanedionato)vanadium(IV) Oxide Triisopropoxyvanadium(V) Oxide Vanadinocene Dichloride
5g
25g 25g 1g
Cr (Chromium) Product No. Product Name B1123 P1347 P0930 P0931 P1088 Q0058 R0004 C0336 T0932
Bis(tetrabutylammonium) Dichromate [Oxidizing Reagent] Chromium(III) Pyridine-2-carboxylate Pyridinium Chlorochromate Pyridinium Dichromate Pyridinium Fluorochromate Quinolinium Dichromate Reinecke Salt Monohydrate Tris(2,4-pentanedionato)chromium(III) Tris(trifluoro-2,4-pentanedionato)chromium(III)
Unit Size 25g
100g 25g
25g
10g 25g 500g 500g 5g 10g 25g 500g 1g
Mn (Manganese) Product No. Product Name H0557 B2409 M0042 T0685 E0095 A0701 N0340 P1742 M0043
Unit Size
Bis(hexafluoroacetylacetonato)manganese(II) Hydrate (1S,2S)-N,N '-Bis[(R)-2-hydroxy-2'-phenyl-1,1'-binaphthyl-3-ylmethylene]1,2-diphenylethylenediaminato Manganese(III) Acetate Bis(2,4-pentanedionato)manganese(II) Dihydrate Bis(trifluoro-2,4-pentanedionato)manganese(II) Ethylenediaminetetraacetic Acid Disodium Manganese Salt Manganese(II) Anthranilate Manganese Naphthenate (Mn ca. 6%) Potassium Permanganate [for General Organic Chemistry] Tris(2,4-pentanedionato)manganese(III)
1g
5g
100mg 500g 5g 25g 5g 25g 500g 300g 25g 500g 25g
Fe (Iron) Product No. Product Name A1138 A0775 N0306 A1601 A0766 B1951 B0886 B2711 B3160 B3196 B2027 B3374 B2226 B2064 D2571 B3501 B3476 B2227 B0885 B2063 B2672 F0312 C1592 F0313 B0913 B0915 D2829 D1272 D0489 D1271 D2537 D2538
384
(R)-(-)-Acetylcarbonyl(η5-2,4-cyclopentadien-1-yl)(triphenylphosphine)iron Acetylferrocene Acid Green 1 Aminoferrocene tert-Amylferrocene η-Benzene(η-cyclopentadienyl)iron(II) Hexafluorophosphate Benzoylferrocene 1,1'-Bis(di-tert-butylphosphino)ferrocene [1,1'-Bis(di-tert-butylphosphino)ferrocene]palladium(II) Dichloride (R,R '')-2,2''-Bis(diphenylphosphino)-1,1''-biferrocene 1,1'-Bis(diphenylphosphino)ferrocene [1,1'-Bis(diphenylphosphino)ferrocene]cobalt(II) Dichloride [1,1'-Bis(diphenylphosphino)ferrocene]nickel(II) Dichloride [1,1'-Bis(diphenylphosphino)ferrocene]palladium(II) Dichloride Dichloromethane Adduct N,N '-Bis(salicylidene)ethylenediamine Iron(II) 1,1'-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ferrocene Bromoferrocene N-(tert-Butoxycarbonyl)aminoferrocene Butylferrocene tert-Butylferrocene 1-Butyl-3-methylimidazolium Tetrachloroferrate Cyclohexenylferrocene Cyclopentadienyliron Dicarbonyl Dimer Cyclopentenylferrocene 1,1'-Diacetylferrocene 1,1'-Dibenzoylferrocene 1,1'-Dibromoferrocene 1,1'-Dibutylferrocene Diethyldithiocarbamic Acid Ferric Salt N,N-Dimethylaminomethylferrocene (R)-N,N-Dimethyl-1-[(S)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine (S)-N,N-Dimethyl-1-[(R)-1',2-bis(diphenylphosphino)ferrocenyl]ethylamine
Availability, price or specification of the listed products are subject to change without prior notice.
Unit Size 10g 25g 100mg 1g 5g 100mg 1g 100mg 1g 5g 1g 1g 1g
5g 5g 1g 1g 10g 1g 5g
5g 1g 1g 5g
100mg 25g 500g 1g 1g 5g 25g 1g 5g 500mg 25g 5g 5g 25g 25g 5g 5g 1g 25g 5g 25g 25g 5g 25g 5g 25g 5g 5g 25g 25g 100mg 100mg
Classes of Metal Compounds
Product No. Product Name D2535 D2536 D1273 D2528 D2529 E0092 E0394 E0706 D1267 D0444 F0406 F0280
(R)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine (S)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine 1,1'-Dimethylferrocene (R)-(+)-N,N-Dimethyl-1-ferrocenylethylamine (S)-(-)-N,N-Dimethyl-1-ferrocenylethylamine Ethylenediaminetetraacetic Acid Monosodium Ferric Salt Hydrate Ethylferrocene 1-Ethyl-3-methylimidazolium Tetrachloroferrate Ferric Dimethyldithiocarbamate Ferrocene Ferroceneacetic Acid Ferroceneboronic Acid (contains varying amounts of Anhydride) [Cyclic boronating reagent
F0165 F0664 B0914 F0320 F0286 F0166 F0167 F0005 G0038 H0008 H0941 H0463 H0464 I0765 F0006 P0774 S0256 S0050 S0820 T2545 T2546 T1686 H0555 I0079 T0750 V0064
Ferrocenecarboxylic Acid 1,1'-Ferrocenediboronic Acid (contains varying amounts of Anhydride) 1,1'-Ferrocenedicarboxylic Acid 3-Ferrocenoylpropionic Acid (Ferrocenylmethyl)dodecyldimethylammonium Bromide (Ferrocenylmethyl)trimethylammonium Bromide (Ferrocenylmethyl)trimethylammonium Iodide Ferroin Solution acc. to JIS K8001 Gluconic Acid Iron(II) Salt Hydrate Hemin (Hydrazinocarbonyl)ferrocene [for HPLC Labeling] 1-Hydroxyethylferrocene Hydroxymethylferrocene Iron(II) Acetate Iron(II) Ethylenediammonium Sulfate Tetrahydrate Iron(II) Phthalocyanine Iron(III) Stearate Sodium Pentacyanoammineferroate(II) Hydrate N-Succinimidyl Ferrocenecarboxylate (R)-(p-Toluenesulfinyl)ferrocene (S)-(p-Toluenesulfinyl)ferrocene Tris(dibenzoylmethanato) Iron Tris(hexafluoroacetylacetonato)iron(III) Tris(2,4-pentanedionato)iron(III) Tris(trifluoro-2,4-pentanedionato)iron(III) Vinylferrocene
Unit Size 5g 200mg 200mg 25g
25g 25g 1g
for GC/MS]
1g
100mg 5g 1g
1g 25g 25g 1g 1g 1g 5g
25g 200mg 1g 1g 5g 25g
100mg 100mg 25g 1g 1g 500g 5g 5g 500g 500g 5g 1g 25g 1g 5g 25g 5g 5g 5g 500g 500g 25g 1g 5g 5g 25g 25g 25g 500g 25g 1g 5g 5g 25g 1g 500g 5g 1g
Co (Cobalt) Product No. Product Name B2314 B2315 C1589 B3374 H0553 B1844 B1845 C0373 B2681 T0746 C2388 N0338 P0887 S0393 D3213 E0089 H0051 S0318 T1861 C0374 C0449
(1R,2R)-N,N '-Bis(2-acetyl-3-oxo-2-butenylidene)-1,2-dimesitylethylenediaminato Cobalt(II) (1S,2S)-N,N '-Bis(2-acetyl-3-oxo-2-butenylidene)-1,2-dimesitylethylenediaminato Cobalt(II) Bis(cyclopentadienyl)cobalt(III) Hexafluorophosphate [1,1'-Bis(diphenylphosphino)ferrocene]cobalt(II) Dichloride Bis(hexafluoroacetylacetonato)cobalt(II) Hydrate (1R,2R)-N,N '-Bis[3-oxo-2-(2,4,6-trimethylbenzoyl)butylidene]1,2-diphenylethylenediaminato Cobalt(II) (1S,2S)-N,N '-Bis[3-oxo-2-(2,4,6-trimethylbenzoyl)butylidene]1,2-diphenylethylenediaminato Cobalt(II) Bis(2,4-pentanedionato)cobalt(II) Dihydrate Bis(2,4-pentanedionato)cobalt(II) Bis(trifluoro-2,4-pentanedionato)cobalt(II) Hydrate Cobalt(II) Chloride Hexahydrate [for General Organic Chemistry] Cobalt Naphthenate Cobalt(II) Phthalocyanine Cobalt(II) Stearate Dicobalt Octacarbonyl (stabilized with 1-5% Hexane) Ethylenediaminetetraacetic Acid Disodium Cobalt Salt Hydrate Hexaamminecobalt(III) Chloride Salcomine [=N,N '-Bis(salicylidene)ethylenediiminocobalt(II)] [5,10,15,20-Tetrakis(4-methoxyphenyl)porphyrinato]cobalt(II) Tris(2,4-pentanedionato)cobalt(III) Vitamin B12
Unit Size 100mg 100mg 1g 1g 5g 5g 100mg
25g
25g 25g
25g
25g 100g 1g 25g 100mg
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
100mg 500g 25g 5g 250g 500g 25g 500g 5g 25g 500g 500g 5g 500g 1g
385
Classes of Metal Compounds
Ni (Nickel) Product No. Product Name B3235 B2225 B2226 B1313 B1350 H0558 N0096 B1371 B3534 B1571 B3354 E0097 B0034 N0850 D1781 D2879 D1574 T0276 A0430 N0861 P1737 P1738 S0487 T1272 T1415 T1416
[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]triphenylphosphine Nickel(II) Dichloride [1,2-Bis(diphenylphosphino)ethane]nickel(II) Dichloride [1,1'-Bis(diphenylphosphino)ferrocene]nickel(II) Dichloride [1,3-Bis(diphenylphosphino)propane]nickel(II) Dichloride Bis(dithiobenzil)nickel(II) Bis(hexafluoroacetylacetonato)nickel(II) Hydrate Bis(2,4-pentanedionato)nickel(II) Hydrate Bis(tetrabutylammonium) Bis(maleonitriledithiolato)nickel(II) Complex Bis(tricyclohexylphosphine)nickel(II) Dichloride Bis(triphenylphosphine)nickel(II) Dichloride Bromo[(2,6-pyridinediyl)bis(3-methyl-1-imidazolyl-2-ylidene)]nickel Bromide Ethylenediaminetetraacetic Acid Disodium Nickel(II) Salt Hydrate Nickel(II) Benzenesulfonate Hexahydrate Nickel(II) Chloride Anhydrous [for General Organic Chemistry] Nickel(II) Dibutyldithiocarbamate Nickel Diethyldithiocarbamate Nickelocene Nickel(II) p-Toluenesulfonate Hexahydrate Nickel p-Toluidine-2-sulfonate Nickel(II) Trifluoromethanesulfonate [N-[α-[2-(Piperidinoacetamido)phenyl]benzylidene]glycinato]nickel [N-[1-[2-(2-Pyridylcarboxamido)phenyl]ethylidene]glycinato]nickel Skeletal Nickel Catalyst slurry in Water [Active catalyst for Hydrogenation] Tetrabutylammonium Bis(1,3-dithiole-2-thione-4,5-dithiolato)nickel(III) Complex Tetrabutylammonium Bis(maleonitriledithiolato)nickel(III) Complex Tetrabutylphosphonium Bis(1,3-dithiole-2-thione-4,5-dithiolato)nickel(III) Complex
Unit Size 1g
200mg 5g 1g 5g 1g 1g 25g
10g
25g 25g 25g 1g
1g 100mg 100mg
1g 25g 5g 25g 25g 5g 500g 1g 1g 100g 1g 25g 25g 500g 500g 500g 5g 25g 25g 5g 1g 1g 50g 100mg 1g 1g
Cu (Copper) Product No. Product Name B3351 H0554 C0384 B1513 B1677 T0752 B1139 C2304 C2422 A1540 C2346 B0491 C1952 D0487 D1022 E0090 G0275 P1005 P1006 C2410 T1292 T1442 C1159 D3891 D2542 C1118 H1194
[1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene](1,3-diphenyl-1,3-propanedionato)copper(I) Bis(hexafluoroacetylacetonato)copper(II) Hydrate Bis(2,4-pentanedionato)copper(II) Bis(1,3-propanediamine) Copper(II) Dichloride Bis(8-quinolinolato)copper(II) Bis(trifluoro-2,4-pentanedionato)copper(II) Bis(triphenylphosphine)copper Tetrahydroborate Chloro[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]copper(I) Chloro(1,3-dimesitylimidazol-2-ylidene)copper(I) Copper(I) Acetate Copper(II) Acetate Monohydrate Copper(II) Bis(2-hydroxyethyl)dithiocarbamate Copper(I) Cyanide Copper Diethyldithiocarbamate Copper(II) Dimethyldithiocarbamate Copper(II) Disodium Ethylenediaminetetraacetate Tetrahydrate Copper(II) Gluconate Copper(II) Phthalocyanine (α-form) Copper(II) Phthalocyanine (β-form) Copper(II) Tetrafluoroborate (ca. 45% in Water) Copper(II) Trifluoromethanesulfonate Copper(I) Trifluoromethanesulfonate Benzene Complex Copper(I) Trifluoromethanethiolate Dichloro(1,10-phenanthroline)copper(II) Di-μ-hydroxo-bis[(N,N,N ',N '-tetramethylethylenediamine)copper(II)] Chloride Direct Blue 86 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-Hexadecafluorophthalocyanine Copper(II)
L0093 P0676 P0655 P1628 P0660 C2409 S0271
Lionol Blue GS Monobutyl Phthalate Copper(II) Salt Pigment Blue 15 Pigment Blue 15 (purified by sublimation) Pigment Green 7 pre-ELM-11 Sodium Copper Chlorophyllin
(purified by sublimation)
386
Unit Size 200mg 1g 25g 1g
200mg 200mg 5g 25g 25g
25g 25g 25g 25g 5g 1g 1g 1g 5g 100mg
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
1g 5g 250g 10g 25g 5g 5g 1g 1g 25g 500g 25g 300g 25g 25g 500g 500g 250g 500g 500g 25g 5g 5g 5g 25g 25g 1g 25g 25g 25g 1g 25g 5g 25g
Classes of Metal Compounds
Product No. Product Name T1256 T2665 T2666
Unit Size
4,4',4'',4'''-Tetra-tert-butylphthalocyanine Copper Tetrakis(acetonitrile)copper(I) Hexafluorophosphate Tetrakis(acetonitrile)copper(I) Tetrafluoroborate
100mg 5g 1g 5g
Zn (Zinc) Product No. Product Name F0093 A0132 B2077 B2078 B0492 Z0002 B1678 B1221
Azoic Diazo Component 48 Basic Orange 14 Bis[2-(2-benzothiazolyl)phenolato]zinc(II) Bis[2-(2-benzoxazolyl)phenolato]zinc(II) Bis(2-hydroxyethyl)dithiocarbamic Acid Zinc(II) Salt Bis(2,4-pentanedionato)zinc(II) Bis(8-quinolinolato)zinc(II) Hydrate Bis(tetrabutylammonium) Bis(1,3-dithiole-2-thione-4,5-dithiolato)zinc Complex
D0138 D0140 D0142 D3214 D3902 E0098 E0778
4-Diazo-N-benzyl-N-ethylaniline Chloride Zinc Chloride 4-Diazo-N,N-dimethylaniline Chloride Zinc Chloride Hydrate 4-Diazo-N-ethyl-N-(2-hydroxyethyl)aniline Chloride Zinc Chloride Diethylzinc (ca. 17% in Hexane, ca. 1mol/L) Diethylzinc (ca. 15% in Toluene, ca. 1mol/L) Ethylenediaminetetraacetic Acid Disodium Zinc Salt Hydrate Ethylmagnesium Chloride (ca. 1.0mol/L in Tetrahydrofuran) activated with Zinc Chloride
F0092 G0215 M0633 P1364
Fast Black K Salt Glycine Zinc Salt Monohydrate [for Protein Research] 2-Mercaptopyridine N-Oxide Zinc Salt Pentamethylene Bis[4-(10,15,20-triphenylporphin-5-yl)benzoate]dizinc(II)
T0279 Z0015 Z0013 Z0014 Z0011 D0157 D0227 D0492 D0717 E0163 G0277 N0341 P0767 T1294
(Toluene-3,4-dithiolato)zinc(II) Zinc (Powder) [for General Organic Chemistry] Zinc Bromide Zinc Chloride Zinc Chloride (16% in Ethyl Ether, ca. 1.0mol/L) Zinc(II) Dibenzyldithiocarbamate Zinc(II) Dibutyldithiocarbamate Zinc Diethyldithiocarbamate Zinc Dimethyldithiocarbamate Zinc N-Ethyl-N-phenyldithiocarbamate Zinc(II) Gluconate Hydrate Zinc Naphthenate Zinc Phthalocyanine Zinc(II) Trifluoromethanesulfonate
Unit Size 1g
25g 5g 5g
[Organic Electronic Material]
25g
25g 25g 500g 25g 100ml 100ml 500g
5g 25g
250g 25g 25g 500g
25g
(ca. 10mol%)
[Reagent for application of the exciton chirality method]
1g
25g 25g 5g 5g 25g 500g 25g
10mg 100mg 1g 5g 300g 25g 300g 25g 300g 100ml 25g 25g 500g 25g 500g 25g 500g 25g 500g 25g 500g 25g 500g 10g 25g 25g
Y (Yttrium) Product No. Product Name T1921
Unit Size
Yttrium(III) Trifluoromethanesulfonate
5g
25g
Zr (Zirconium) Product No. Product Name C1995 D3307 D3321 I0645 Z0006 T0747 Z0016 Z0017 Z0009 Z0010 Z0007
Cyclopentadienylzirconium(IV) Trichloride Decamethylzirconocene Dichloride 1,1'-Dibutylzirconocene Dichloride 1,1'-Isopropylidenezirconocene Dichloride Tetrakis(2,4-pentanedionato)zirconium(IV) Tetrakis(trifluoro-2,4-pentanedionato)zirconium(IV) Zirconium(IV) Butoxide (ca. 80% in 1-Butanol) Zirconium(IV) Propoxide (ca. 70% in 1-Propanol) Zirconocene Bis(trifluoromethanesulfonate) Tetrahydrofuran Adduct Zirconocene Chloride Hydride Zirconocene Dichloride
Unit Size 1g 1g 25g
1g
25g 25g 1g 5g 5g
5g 1g 5g 100mg 500g 1g 500g 100g 5g 25g 25g
Mo (Molybdenum) Product No. Product Name M0464 P1484
Unit Size
Bis(2,4-pentanedionato)molybdenum(VI) Dioxide Phosphomolybdic Acid Ethanol Solution [for TLC Stain]
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 500ml
387
Classes of Metal Compounds
Product No. Product Name P1910 T2358
Unit Size
Phosphomolybdic Acid Hydrate Tris(N-tert-butyl-3,5-dimethylanilino)molybdenum(III)
100mg 100mg
Ru (Ruthenium) Product No. Product Name B1902 B3067 B3068 C2251 C1944 C2201 D2751 H1010 P1688 P1427 P1698 R0076 R0074 R0086 R0078 T1559 T2181 T1655 T2183 D1997
Unit Size
Benzeneruthenium(II) Chloride Dimer [(R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II) Dichloride [(S)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II) Dichloride Carbonyl(dihydrido)tris(triphenylphosphine)ruthenium(II) Chloronitrosyl[N,N '-bis(3,5-di-tert-butylsalicylidene)-1,1,2,2-tetramethylethylenediaminato]ruthenium(IV) Cyclopentadienylbis(triphenylphosphine)ruthenium(II) Chloride Dichloro(p-cymene)ruthenium(II) Dimer (Hexamethylbenzene)ruthenium(II) Dichloride Dimer (3-Phenyl-1H-inden-1-ylidene)bis(tricyclohexylphosphine)ruthenium(IV) Dichloride
1g
5g 250mg 250mg 250mg 1g
Tetrahydrofuran Adduct
100mg
1g 100mg
200mg 5g 1g
1g 25g 5g 1g 1g 5g 1g 5g 5g 5g
1g 1g
Polyethylene Glycol-bound Ruthenium Carbene Complex Poly[[N-isopropylacrylamide-co-[N-[3-(dodecyldimethylammonio)propyl]acrylamide]co-(1,3,5-triacryloylhexahydro-1,3,5-triazine)]perruthenate] Ruthenium 5% on Carbon (wetted with ca. 50% Water) Ruthenium(III) Chloride Ruthenium(II) Nitrosyl Chloride Monohydrate Ruthenocene Tetrapropylammonium Perruthenate Triruthenium Dodecacarbonyl Tris(2,2'-bipyridyl)ruthenium(II) Chloride Hexahydrate Tris(2,4-pentanedionato)ruthenium(III) Tris(triphenylphosphine)ruthenium(II) Dichloride
1g 100mg 1g 1g 1g
100mg 5g 5g 1g
Rh (Rhodium) Product No. Product Name B2090 B2091 B1692 C1383 C2253 B1045 N0453 P1788 R0075 R0069 T2054 T2055 T1551 T2658 T2659 T2660 T2661 T1544 T0931
Unit Size
(S,S)-1,2-Bis[(tert-butyl)methylphosphino]ethane[η-(2,5-norbornadiene)]rhodium(I) Tetrafluoroborate Bis[η-(2,5-norbornadiene)]rhodium(I) Tetrafluoroborate Carbonylbis(triphenylphosphine)rhodium(I) Chloride Carbonyltris(triphenylphosphine)rhodium(I) Hydride Chlorobis(cyclooctene)rhodium(I) Dimer Chloro(1,5-cyclooctadiene)rhodium(I) Dimer Norbornadiene Rhodium(I) Chloride Dimer (Pentamethylcyclopentadienyl)rhodium(III) Dichloride Dimer Rhodium 5% on Carbon (wetted with ca. 55% Water) Rhodium(II) Acetate Dimer Tetrakis[N-phthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-phthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-phthaloyl-(S)-phenylalaninato]dirhodium Ethyl Acetate Adduct Tetrakis[N-tetrachlorophthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrachlorophthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrafluorophthaloyl-(R)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis[N-tetrafluorophthaloyl-(S)-tert-leucinato]dirhodium Bis(ethyl Acetate) Adduct Tetrakis(triphenylacetato)dirhodium(II) Dichloromethane Adduct Tris(triphenylphosphine)rhodium(I) Chloride
100mg 1g 100mg 100mg
100mg
1g
50mg 1g 1g 5g 500mg 1g 100mg 200mg 1g 1g 100mg 100mg 100mg 50mg 100mg 50mg 100mg 100mg 5g
Pd (Palladium) Product No. Product Name A1479 B2029 B1676 B1668 B3224 B1374 B3160 B2031 B2016 B2064
388
Allylpalladium(II) Chloride Dimer Benzylbis(triphenylphosphine)palladium(II) Chloride Bis(acetonitrile)palladium(II) Dichloride Bis(benzonitrile)palladium(II) Dichloride Bis[1,2-bis(diphenylphosphino)ethane]palladium(0) Bis(dibenzylideneacetone)palladium(0) [1,1'-Bis(di-tert-butylphosphino)ferrocene]palladium(II) Dichloride [1,4-Bis(diphenylphosphino)butane]palladium(II) Dichloride [1,2-Bis(diphenylphosphino)ethane]palladium(II) Dichloride [1,1'-Bis(diphenylphosphino)ferrocene]palladium(II) Dichloride Dichloromethane Adduct
Unit Size
1g
500mg 100mg 1g 1g 1g 1g 1g 1g 1g
1g 1g 5g 5g 5g 5g 5g 5g 5g
5g
25g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
Classes of Metal Compounds
Product No. Product Name B2192 B2244 B2161 B2018 B3292 B1437 B3161 B2055 B2042 B1667 B2026 B3553 C2387 C2372 C2406
C2407 C2347 D3704 D3806 D3847 D3807 D2604 D3706 N0842 P1702 P1703 P1491 P1785 P1490 P1701 A1424 P1430
[1,3-Bis(diphenylphosphino)propane]palladium(II) Dichloride Bis(ethylenediamine)palladium(II) Dichloride Bis(methyldiphenylphosphine)palladium(II) Dichloride Bis(2,4-pentanedionato)palladium(II) 1,2-Bis(phenylsulfinyl)ethane Palladium(II) Diacetate Bis(tetrabutylammonium) Bis(1,3-dithiole-2-thione-4,5-dithiolato)palladium(II) Bis(tri-tert-butylphosphine)palladium(0) Bis(tricyclohexylphosphine)palladium(II) Dichloride Bis(triphenylphosphine)palladium(II) Diacetate Bis(triphenylphosphine)palladium(II) Dichloride Bis(tri-o-tolylphosphine)palladium(II) Dichloride Bromo[[1,3-bis[(4S,5S)-1-benzoyl-4,5-diphenyl-2-imidazolin2-yl]benzene]palladium(II)] Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](acetanilide)palladium(II)] (This product is unavailable for selling domestically in U.S.) Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](N,N-dimethylbenzylamine)palladium(II)] (This product is unavailable for selling domestically in U.S.) Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](N,N-dimethyl3,5-dimethoxybenzylamine)palladium(II)] (This product is unavailable for selling domestically in U.S.) Chloro[[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](4'-methoxyacetanilide)palladium(II)] (This product is unavailable for selling domestically in U.S.) Chloro[(1,3-dimesitylimidazol-2-ylidene)(N,N-dimethylbenzylamine)palladium(II)] [Di-tert-butyl(chloro)phosphine]palladium(II) Dichloride Dimer Di-μ-chlorobis[5-chloro-2-[(4-chlorophenyl)(hydroxyimino)methyl]phenyl]palladium(II) Dimer Di-μ-chlorobis[2-[(dimethylamino)methyl]phenyl-C,N]dipalladium(II) Di-μ-chlorobis[5-hydroxy-2-[1-(hydroxyimino)ethyl]phenyl]palladium(II) Dimer Dichloro(1,5-cyclooctadiene)palladium(II) Dihydrogen Di-μ-chlorotetrakis(di-tert-butylphosphinito)dipalladate 2,5-Norbornadiene Palladium(II) Dichloride Palladium 5% on Barium Sulfate Palladium 5% on Calcium Carbonate (poisoned with Lead) Palladium 10% on Carbon (wetted with ca. 55% Water) Palladium 10% on Carbon (wetted with ca. 55% Water) [Useful catalyst for coupling reaction, etc.] Palladium 5% on Carbon (wetted with ca. 55% Water) Palladium 5% on Barium Carbonate Palladium(II) Acetate Palladium Catalyst Set (includes useful 7 Palladium catalysts)
Unit Size 1g 1g 1g 200mg 100mg 250mg 1g 1g 1g 5g
100mg
200mg
200mg
1g
200mg
1g
200mg
1g
200mg 1g
1g 5g 100mg
250mg
1g 1g 1g 5g 100mg 1g 25g 25g 25g 25g 25g 10g 5g
250mg 1g
5g 5g 5g 5g 5g 1g
Palladium(II) Acetate Allylpalladium(II) Chloride Dimer Bis(benzonitrile)palladium(II) Dichloride Bis(dibenzylideneacetone)palladium(0) [1,1'-Bis(diphenylphosphino)ferrocene]palladium(II) Dichloride Dichloromethane Adduct Bis(triphenylphosphine)palladium(II) Dichloride Tetrakis(triphenylphosphine)palladium(0)
P1489 P1528 P1786 P1870 P1425
Palladium(II) Chloride Palladium Hydroxide 20% on Carbon (wetted with ca. 50% Water) Palladium on SH Silica Gel (0.1mmol/g) Palladium(II) Trifluoroacetate Poly[N-isopropylacrylamide-co-4-(diphenylphosphino)styrene] Palladium(II) Dichloride
S0540 T1350 T2184
Sodium Tetrachloropalladate(II) Tetrakis(triphenylphosphine)palladium(0) Tris(dibenzylideneacetone)dipalladium(0)
5g 1g 5g 5g 1g 1g 1g 5g 5g 25g 1g
1g 10g 1g 100mg
(ratio, acrylamide:phosphine=20:2)
1g
5g 1g
1set 5g 50g 1g 5g 1g 1g 25g 5g
Ag (Silver) Product No. Product Name C2373 D1679 S0363 B0398 D0490 D1401 S0463 S0815 S0595 S0446 T1331
Chloro[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]silver Dithizone Silver Complex Phthalocyanine Silver Silver Behenate Silver N,N-Diethyldithiocarbamate [for As analysis] Silver Diethyldithiocarbamate - Brucine (Chloroform Solution) [for As Analysis] Silver Hexafluoroantimonate(V) Silver(II) Picolinate Silver Sulfadiazine Silver Tetrafluoroborate Silver Trifluoromethanesulfonate
Unit Size 200mg
5g 5g 5g 5g 5g 10g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
1g 1g 1g 25g 25g 250ml 25g 1g 25g 25g 25g
389
Classes of Metal Compounds
Cd (Cadmium) Product No. Product Name E0087
Unit Size
Ethylenediaminetetraacetic Acid Cadmium Disodium Salt Hydrate
25g
La (Lanthanum) Product No. Product Name C0079 T1293 L0148
Unit Size
Chloranilic Acid Lanthanum(III) Salt Decahydrate Lanthanum(III) Trifluoromethanesulfonate Tris(2,4-pentanedionato)lanthanum(III) Hydrate
5g 5g
25g 25g 25g
Ce (Cerium) Product No. Product Name C2058 T1918
Unit Size
Cerium(III) Chloride Anhydrous Cerium(III) Trifluoromethanesulfonate
5g
25g 5g
Pr (Praseodymium) Product No. Product Name T1511 T1264
Unit Size
Tris(6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedionato)praseodymium(III) [NMR Shift Reagent] Tris(2,2,6,6-tetramethyl-3,5-heptanedionato) Praseodymium(III) [NMR Shift Reagent]
1g 1g
Nd (Neodymium) Product No. Product Name T1919
Unit Size
Neodymium(III) Trifluoromethanesulfonate
5g
25g
Sm (Samarium) Product No. Product Name S0494 S0473 S0474
Unit Size
Samarium(II) Iodide (ca. 0.1mol/L in Tetrahydrofuran) Sodium [(R)-1,2-Diaminopropane-N,N,N ',N '-tetraacetato]samarate(III) Hydrate Sodium [(S)-1,2-Diaminopropane-N,N,N ',N '-tetraacetato]samarate(III)
25ml 100mg 100mg
Eu (Europium) Product No. Product Name A2083 E0707 P1766 T1735 T1265
Unit Size
ATBTA-Eu3+ Europium(III) Chloride Hexahydrate (1,10-Phenanthroline)tris[4,4,4-trifluoro-1-(2-thienyl)-1,3-butanedionato]europium(III) Tris(1,3-diphenyl-1,3-propanedionato)(1,10-phenanthroline)europium(III) Tris(2,2,6,6-tetramethyl-3,5-heptanedionato)europium(III) [NMR Shift Reagent]
100mg 5g 1g 1g 5g 1g 5g
Tm (Thulium) Product No. Product Name T1920
Unit Size
Thulium(III) Trifluoromethanesulfonate
5g
Yb (Ytterbium) Product No. Product Name T1610
Unit Size
Ytterbium(III) Trifluoromethanesulfonate Hydrate
5g
25g
Hf (Hafnium) Product No. Product Name D3286 T1708 H0914
1,1'-Dipropylhafnocene Dichloride Hafnium(IV) Trifluoromethanesulfonate Hafnocene Dichloride
Unit Size 1g
1g 5g
1g 5g 25g
W (Tungsten) Product No. Product Name P1697
390
Poly[[N-isopropylacrylamide-co-[N-[3-(dodecyldimethylammonio)propyl]acrylamide]]phosphotungstate]
Unit Size 200mg
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
1g
Classes of Metal Compounds
Re (Rhenium) Product No. Product Name T1803
Tetrabutylammonium Perrhenate
Unit Size 1g
5g
Os (Osmium) Product No. Product Name O0308
Unit Size
Osmium Tetroxide (4% in Water)
10ml
Ir (Iridium) Product No. Product Name C1807 I0616 P1763 T2557 T2685 T1946
Chloro(1,5-cyclooctadiene)iridium(I) Dimer Iridium(III) Chloride Hydrate (Pentamethylcyclopentadienyl)iridium(III) Dichloride Dimer Tris(2,4-pentanedionato)iridium(III) Tris[1-phenylisoquinoline-C 2,N]iridium(III) (purified by sublimation) Tris(2-phenylpyridinato)iridium(III) (purified by sublimation)
Unit Size 1g
1g 5g 1g 1g 100mg 200mg
Pt (Platinum) Product No. Product Name B3115 B1438 B3162 C2043 D3371 D3592 H1287 O0372 T2485
Bis(2,4-pentanedionato)platinum(II) Bis(tetrabutylammonium) Bis(1,3-dithiole-2-thione-4,5-dithiolato)platinum(II) Bis(tri-tert-butylphosphine)platinum(0) Carboplatin cis-Diammineplatinum(II) Dichloride Dichloro(1,5-cyclooctadiene)platinum(II) Hydrogen Hexachloroplatinate(IV) Hexahydrate Oxaliplatin Tetrakis(triphenylphosphine)platinum(0)
Unit Size 1g 100mg 250mg 100mg 1g 100mg 1g 200mg 1g 1g 100mg 1g
Au (Gold) Product No. Product Name C2405 D2134 T1261 T1273 T1357
Chloro[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]gold(I) Dioctadecyldimethylammonium Bis(1,3-dithiole-2-thione-4,5-dithiolato)aurate(III) Tetrabutylammonium Dibromoaurate Tetrabutylammonium Dichloroaurate Tetrabutylammonium Diiodoaurate
Unit Size 200mg
1g 100mg 1g 100mg 100mg 1g
Hg (Mercury) Product No. Product Name A0099 B0862 C0194 C0196 D0954 C0080 M0589 M0258 P0192 P0769 P0176 P0337 P0193 P0194 C0195 T0702 T0322
1-(4-Acetoxymercuriphenylazo)-2-naphthol 3,6(2,5)-Bis(acetatemercurimethyl)-1,4-dioxane 4-Chloromercuribenzoic Acid 1-(4-Chloromercuriphenylazo)-2-naphthol Di-p-tolylmercury Mercuric Chloranilate Methylmercuric Chloride Methylmercuric Iodide Phenylmercuric Acetate Phenylmercuric Borate (mixed Phenylmercury Hydroxide) Phenylmercuric Chloride Phenylmercuric Iodide Phenylmercuric Nitrate Phenylmercuric Oleate Sodium 4-Chloromercuribenzoate Thimerosal p-Tolylmercuric Chloride
Unit Size 1g 100mg
5g
1g
1g 5g 25g 1g 1g 5g 5g 25g 25g 25g 10g 25g 25g 25g 1g 10g 25g
Semimetal Compounds B（Boron) (see p.357) Si（Silicon) (for Organic Synthesis) (see p.162) This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
391
Classes of Metal Compounds
Ge (Germanium) Product No. Product Name B1367 D1824 P1003 T1156 T1157 T1158 T1159 T1160 T1161 T1162
Bis[2-carboxyethylgermanium(IV)] Sesquioxide Diphenyldichlorogermane Phenyltrichlorogermane Tetrabutylgermane Tetraethylgermane Tetramethylgermane Tetraphenylgermane Triethylchlorogermane Trimethylchlorogermane Triphenylchlorogermane
Unit Size 5g
1g
25g 1g 1g 1g 1g 5g 1g 1g 1g 1g
As (Arsenic) Product No. Product Name A0529 A0530 D0578 A5009
2-Aminophenylarsonic Acid 4-Aminophenylarsonic Acid Arsenazo I Hydrate Arsenazo III [Spectrophotometric reagent for U, Th, Zr and other metals, Indicator for the precipitation
C1072 D0659 D2248 H0287 H0201 M0327 N0133 P0140 B0021 H0817 A0531 T0162 H0240 T0508
Cacodylic Acid 4-(4-Dimethylaminophenylazo)phenylarsonic Acid Hydrochloride Diphenyliodonium Hexafluoroarsenate 4-Hydroxy-3-nitrophenylarsonic Acid 4-Hydroxyphenylarsonic Acid Methyltriphenylarsonium Iodide 2-Nitrophenylarsonic Acid Phenylarsine Oxide Phenylarsonic Acid Potassium Hexafluoroarsenate Sodium 4-Aminophenylarsonate Tetraphenylarsonium Chloride Hydrochloride Hydrate Thorin Hydrate [for Determination of Th, etc.] Triphenylarsine
titration of SO4 with Ba]
Unit Size 5g 25g 1g
25g 500g 25g
1g 5g 1g
5g 25g 25g 1g 25g 25g 5g 25g 5g 25g 10g 500g 1g 25g 5g
1g
25g 1g
Se (Selenium) Product No. Product Name B2134 B2105 B1375 D2717 D3944 D3290 D1289 D2186 M1900 P1322 P1091 S0462 S0442 S0829 T1819
Benzeneseleninic Acid Benzeneselenol Bis(4-methoxyphenyl) Selenoxide Dibenzyl Diselenide 4,7-Dibromo-2,1,3-benzoselenadiazole Dimethyl Diselenide Dimethylselenide Diphenyl Diselenide 5-Methoxy-2-methylbenzoselenazole Phenylselenenyl Bromide Phenylselenenyl Chloride DL-Selenomethionine L-Selenomethionine Selenophene Triphenylphosphine Selenide
Unit Size 5g 1g
1g 5g 1g 5g 5g 1g 1g
25g 5g 5g 5g 1g 5g 1g 25g 5g 25g 25g 1g 5g 5g 5g
Sb (Antimony) Product No. Product Name S0463 T1847 T0476 T1848 T1849 T1850
Silver Hexafluoroantimonate(V) Tetraphenylantimony Bromide Triphenylantimony Triphenylantimony Diacetate Triphenylantimony Dichloride Triphenylantimony Oxide
Unit Size 5g
1g
25g 1g 25g 1g 1g 5g
Te (Tellurium) Product No. Product Name D2718
392
Diphenyl Ditelluride
Unit Size 1g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
5g
Classes of Metal Compounds
Bi (Bismuth) Product No. Product Name B3546 E0086 T1835 T1836 T1837 T2657 T0511 T2507 T1956 T1838 T2038 T1957 T1970 T2261
Bismuth(III) Chloride Anhydrous [for General Organic Chemistry] Bismuth Sodium Ethylenediaminetetraacetate Triphenylbismuth Carbonate Triphenylbismuth Diacetate Triphenylbismuth Dichloride Triphenylbismuth Difluoride Triphenylbismuthine Triphenyl-2,6-xylylbismuthonium Tetrafluoroborate Tris(2-methoxyphenyl)bismuth Dichloride Tris(2-methoxyphenyl)bismuthine Tris(4-trifluoromethylphenyl)bismuth Dichloride Tri-o-tolylbismuth Dichloride Tri-o-tolylbismuthine Tri-p-tolylbismuthine
Unit Size 25g
1g 5g 100mg 1g 1g 1g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
250g 25g 1g 5g 5g 5g 25g 1g 5g 5g 1g 5g 5g 1g
393
Non-benzenoid Aromatic Compounds
Non-benzenoid Aromatic Compounds Azulene, which has a specific structure of ring-fused unsaturated seven-membered and five-membered rings, is a typical non-benzenoid aromatic compound. Whereas naphthalene or other hydrocarbon compounds are generally colorless, azulene, a structural isomer of naphthalene, is dark blue, and the name comes from the Spanish word azul, meaning "blue". Three practical manufacturing methods have been known so far as follows: The first method, which was developed by Ziegler and Hafner, is a reaction of ring-opened pyridinium salts or pyrylium salts with cyclopentadienides. The second one, which was developed by Nozoe and Seto is a reaction of tropone derivatives bearing halogen, methoxy, or tosyloxy groups at the 2 position and active methylene compounds, such as cyanoacetates and malonates, in the presence of base. The last method, which was developed by Yasunami and Takase ., is a reaction of oxaazulanones with enamines. Tropolone derivatives are also classified as non-benzenoid aromatic compounds. Hinokitiol, a typical tropolone compound, has been known to exhibit an antibacterial effect. Also colchicine, an alkaloid compound with a tropolone ring, shows strong antitumor effects. Thus, tropolone compounds have possibilities in the pharmaceutical field, especially for anticancer drugs.
A0634
G0228 CH3
Azulenes
CH3
CH3 CH3
Product No. Product Name A0634 G0228
Unit Size
Azulene Guaiazulene
100mg
I0657 CH3 CH3
M1188
CH
Oxaazulanones
O
O
O
C OCH3
C OCH3
O
O
O
Product No. Product Name I0657 M1188
Unit Size
5-Isopropyl-3-(methoxycarbonyl)-2H-cyclohepta[b]furan-2-one 3-(Methoxycarbonyl)-2H-cyclohepta[b]furan-2-one
C0380
5g 1g
D1791
CH3O
H0142 O
O NH C CH3
HO
CH3O
Tropones & Tropolones
CH3O O OCH3
394
1g 10g
O CH3
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
CH3
Non-benzenoid Aromatic Compounds
P0542
T0606 OH
T1574 O
O
OH
O
HO
O
CH3
O S
OH
O
OH
Product No. Product Name C0380 D1791 H0142 P0542 T0606 T1574
Unit Size
Colchicine (contains 5% Ethyl Acetate at maximum) Dibenzosuberenone Hinokitiol Purpurogallin Tropolone Tropolone Tosylate
500mg 1g 1g
D2785
D2786
CHN
D2787
CH3 CH3 C
Pentafulvenes
CH3
C
CH3
Product No. Product Name D2785 D2786 D2787
Unit Size
6-(Dimethylamino)fulvene 6,6-Dimethylfulvene 6,6-Diphenylfulvene
1g
T1118
Tropylium Ions
1g 1g 5g
T1121
PF6
Product No. Product Name T1118 T1121
5g 5g
5g 25g 5g 1g 25g 25g
BF4
Unit Size
Tropylium Hexafluorophosphate Tropylium Tetrafluoroborate
1g 5g
References 1) 2) 3) 4)
1955, K. Ziegler, K. Hafner, , 301. 1956, T. Nozoe, S. Seto, S. Matsumura, T. Asano, , 339. 1971, 4275. P. W. Yang, M. Yasunami, K. Takase, 1992, Reviews: M. Yamato, , 81; K. Takase, M. Yasunami, 1981, , 1172; T. Asao, S. Ito,
1996,
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
, 2.
395
NMR Spectrometry
NMR Spectrometry Deuterated Compounds for NMR Product No. Product Name A0636 A0637 A0638 A2050 A2018 A2074 B0840 B3008 B0825 C0583 C2181 C0023 C1423 C2215 C2232 H0341 W0002 W0004 D3529 D3569 D3530 D0381 D3527 E0221 E0357 E0728 F0198 F0247 H0693 M0551 M1869 M1888 P0634 P0648 S0155 T2425 T0597
CH3COOD Acetic Acid-d1 98atom%D CD3COOD Acetic Acid-d4 99.5atom%D C3D6O Acetone-d6 99.9atom%D C3D6O Acetone-d6 99.9atom%D CD3CN Acetonitrile-d3 99.8atom%D CD3CN Acetonitrile-d3 99.8atom%D C6D6 Benzene-d6 99.6atom%D C6D6 Benzene-d6 99.6atom%D CH3(CH2)3OD Butanol-d1 97atom%D CDCl3 Chloroform-d 99.6atom%D (stabilized with Silver chip) CDCl3 Chloroform-d 99.96atom%D (stabilized with Silver chip) Chloroform-d 99.6atom%D (containing 1wt% TMS) (stabilized with Silver chip) CDCl3 Chloroform-d 99.6atom%D (containing 0.05wt% TMS) (stabilized with Silver chip) CDCl3 CDCl3 Chloroform-d 99.96atom%D CDCl3 Chloroform-d 99.8atom%D DBr Deuterium Bromide 98.0atom%D (45% in D2O) D2O Deuterium Oxide 99.8atom%D D2O Deuterium Oxide 99.9atom%D CD2Cl2 Dichloromethane-d2 99.9atom%D CD2Cl2 Dichloromethane-d2 99.9atom%D (CD3)2NCDO N,N-Dimethylformamide-d7 99.5atom%D CD3SOCD3 Dimethyl Sulfoxide-d6 99.9atom%D CD3SOCD3 Dimethyl Sulfoxide-d6 99.9atom%D CH3CH2OD Ethanol-d1 (contains 5% D2O) CD3CH2OH Ethanol-d3 99.5atom%D CD3CD2OD Ethanol-d6 99.5atom%D DCOOH Formic Acid C-d 99atom%D HCOOD Formic Acid O-d CF3COCF3・3D2O Hexafluoroacetone Deuterate CH3OD Methanol-d1 CD3OD Methanol-d4 99.8atom%D CD3OD Methanol-d4 99.8atom%D CH3(CH2)2OD 1-Propanol-d1 98atom%D C5D5N Pyridine-d5 99.5atom%D D2SO4 Sulfuric Acid-d2 C4D8O Tetrahydrofuran-d8 99.5atom%D CF3COOD Trifluoroacetic Acid-d
Unit Size 5g 25g 10ml 0.75ml×10 10g 0.75ml×10 25ml 0.75ml×10 5g 10g 100g 25g 25g 25g 0.75ml×10 0.75ml×10 5g 10ml 100ml 0.75ml×10 5g 0.75ml×5 0.75ml×5 25g 0.75ml×10 25ml 1ml 1ml 1g 5g 1g 5g 5g 10g 0.75ml×10 5g 1ml 10g 0.75ml×5 5g 5g
Standards for NMR Product No. Product Name C0023 C1423 H0638 H0091 T1638 T0154
Chloroform-d (containing 1wt% TMS) 99.6atom%D (stabilized with Silver chip) Chloroform-d (containing 0.05wt% TMS) 99.6atom%D (stabilized with Silver chip) Hexamethyldisilane Hexamethyldisiloxane Sodium 3-(Trimethylsilyl)-1-propanesulfonate Tetramethylsilane
Unit Size 10ml 25ml 1g 25ml
25g 25g 100ml 500ml 5g 500ml
Chemical Shift Standards for Multinuclear NMR
396
Product No. Product Name
Unit Size
B0527 D1289 H0085 N0209
25ml
Boron Trifluoride - Ethyl Ether Complex Dimethylselenide Hexafluorobenzene Nitromethane
25g 25g
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
500ml 1g 250g 500g
NMR Spectrometry
Product No. Product Name
Unit Size
T0919 T0488 Z0007
5g 25ml 5g
Tetramethyltin Trimethyl Phosphite Zirconocene Dichloride
25g 500ml 25g
Enantiomer Excess & Absolute Configuration Determination (see p.67)
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
397
Standards for Mass Spectrometry & Matrix Materials
Standards for Mass Spectrometry & Matrix Materials Standards for Mass Spectrometry Product No. Product Name
Unit Size
P0690 P0689 P1034 P1061 P0074 P0966 T0858 T0859 T0828 T0829
Perfluorokerosene (Low boiling) Perfluorokerosene (High boiling) Perfluorokerosene (Super-high boiling) Perfluorokerosene (Super-high boiling) (50% in PFK Low boiling) Perfluorotributylamine Poly(perfluoropropylene Oxide) 2,4,6-Tris(pentafluoroethyl)-1,3,5-triazine 2,4,6-Tris(heptafluoropropyl)-1,3,5-triazine 2,4,6-Tris(pentadecafluoroheptyl)-1,3,5-triazine 2,4,6-Tris(nonadecafluorononyl)-1,3,5-triazine
P1185
Polyethylene Glycol 600 Sulfate [for Negative Ion FABMS Standard]
[Mass Spectrum] Data : fr 1 Sample : PEG 600 Sulfate RT : 0.203 Mode : MF-FAB[Neg.] BP : M/Z = 97.0000 INT. = 1175.51 Scan# : 3
Negative FABMS spectrum of P1185 PEG 600 Sulfate
398
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
10g 1g 5g 5g 25g 10g 0.1ml 0.1ml 100mg 100mg 1g
Standards for Mass Spectrometry & Matrix Materials
FABMS & Liquid SIMS Matrix Materials Product No. Product Name S0376 S0436 S0437 S0373 S0375 S0378 S0380 S0374 S0377
Diethanolamine DTT / TG11 [Dithiothreitol + α-Thioglycerol] (1:1 mixture) DTT / TG12 [Dithiothreitol + α-Thioglycerol] (1:2 mixture) Glycerol Magic Bullet [mixture of Dithiothreitol and Dithioerythritol (3:1)] 3-Nitrobenzyl Alcohol 2-Nitrophenyl n-Octyl Ether α-Thioglycerol Triethanolamine
Unit Size 1g
1g 1g 1g 1g 1g
10g 1g 1g 10g 1g 10g 10g 10g 10g
MALDI-TOF-MS Matrix Materials Product No. Product Name A0859 B3635 C1768 C0353 E0386 D0569 H0586 H0787 I0025 N0082 D2932 T1888
3-Amino-4-hydroxybenzoic Acid trans-2-[3-(4-tert-Butylphenyl)-2-methyl-2-propenylidene]malononitrile α-CHCA trans-Cinnamic Acid Esculetin Gentisic Acid 4-Hydroxyazobenzene-2'-carboxylic Acid 3-Hydroxypicolinic Acid 3-Indoleacrylic Acid Nicotinic Acid Sinapinic Acid 2',4',6'-Trihydroxyacetophenone Monohydrate
Unit Size 5g 100mg 25g 25g 5g 5g 1g 25g 5g
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
25g 1g 1g 500g 1g 500g 25g 25g 5g 500g 5g 25g
399
TLC Stains
TLC Stains GC and HPLC are commonly used as methods for highly sensitive separation analysis. Novel detection methods and high resolution columns have been developed, thereby highly-sensitive and highly-selective separation analysis is now routinely performed. Furthermore, the substances that are being analyzed are of a wide variety, ranging from such things as trace biological constituents to trace environmental pollutants. GC and HPLC are playing important roles in the advancement of today’ s microanalytical technology. Thin-layer chromatography (TLC) is also an important analytical tool, being used to confirm the progress of reaction, and for evaluation of HPLC separation conditions. Furthermore, the Japanese Pharmacopoeia (JP) has established that the identification tests by TLC must be conducted for many of the natural medicines, such as Scutellaria Root, Phellodendron Bark and Rhubarb, etc. As mentioned, TLC is still an important method of simple separation analysis, which widely used in the many fields. The Rf-value is a very important piece of data that is provided by TLC. When TLC development conditions are same, the Rf-value is characteristic for a substance. Therefore, the Rf-values are often used for identification of substances. Additionally, selective detection of compounds is possible by choosing the appropriate TLC stains. For example, after development of the TLC plate, if one seeks to identify a compound containing an amino group, the TLC plate is treated with ninhydrin solution which stain only those compounds with an amino group. There are many types of TLC stains reported and used. To obtain accurate results, it is important to select the appropriate TLC stains. The below table indicates typical TLC stains and the corresponding functional groups. Each of them is prepared so that can be used straight away after the TLC development.
Prepared TLC Stains Product No. A1674
P1484
P1483
N0719 D2968 B2401
C1794
Product Name p-Anisaldehyde (Ethanol Solution) (contains Acetic Acid, H2SO4) Phosphomolybdic Acid (Ethanol Solution) (PMA)
Potassium Permanganate Solution (contains K2CO3, NaOH)
Treatment
Target Compounds
Heat
Versatile-type, effective with almost all functional groups, esp. nucleophilic ones such as phenols, sugars
500ml
Heat
Versatile-type, effective with almost all functional groups
500ml
Versatile-type, effective with oxidizable functional groups, multiple-bond, alcohols, amines, sulfides, mercaptans
500ml
−
Unit size
Ninhydrin (Ethanol Solution) (contains Acetic Acid)
Heat
Amines, amino acids, Boc protected amino groups after deprotection while on the TLC plate
500ml
2,4-Dinitrophenylhydrazine
Heat
Aldehydes, ketones
500ml
−
Compounds with acidic functional groups, carboxylic acids, sulfonic acids, etc.
500ml
Heat
Effective with almost all functional groups
500ml
Heat
Alcohols, phenols
500ml
(Ethanol Solution) (contains HCl)
Bromocresol Green (BCG) (Ethanol Solution) (contains NaOH)
Ceric Ammonium Molybdate Solution (CAM) (contains H2SO4)
V0080
Vanillin (Ethanol Solution) (contains H2SO4)
Related product Product No. Product Name N0094
400
Unit Size
Ninhydrin Spray (0.5% in 1-Butanol)
The chemical, physical and toxicological properties of some chemicals have not been thoroughly investigated. Please handle with care.
200ml
This TCI Reagent Guide is not an all inclusive guide of all the products available from us. Please refer to our catalog for further information or visit our web site.
401
Abbreviations Descriptors ompnprim sec tert αβγδεημ-
ortho meta para normal primary secondary tertiary alpha beta gamma delta epsilon eta mu
τωBNOPScis trans (Z )(E )threo erythro D-
tau(tele) omega boron position nitrogen position oxygen position phosphorus position sulfur position cis form trans form Z（zusammen）form E（entgegen）form threo form erythro form D form
LDL-
d - or (+)l - or (−)dl - or (±)(R )(S )meso syn anti asym s- or sym active leuco -
L form DL form dextro rotation levo rotation racemic mixture R（rectus）form S（sinister）form meso form syn form anti form asymmetric form symmetric form active form leuco form
Products / Ligands acac AIBN BINAP BINOL BSA CD CSA DABCO DAST DBU DCC DEAD DHP DMA DMAP DMF dmit DMSO DOXYL dppf DVB EDC EDTA Fc HMDS HMPA
Acetylacetone 2,2'-Azobis(isobutyronitrile) 2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl Binaphthol N ,O -Bis(trimethylsilyl)acetamide Cyclodextrin Camphorsulfonic Acid 1,4-Diazabicyclo[2.2.2]octane (Diethylamino)sulfur Trifluoride 1,8-Diazabicyclo[5.4.0]-7-undecene N ,N '-Dicyclohexylcarbodiimide Diethyl Azodicarboxylate 3,4-Dihydro-2H -pyran N ,N -Dimethylacetamide 4-Dimethylaminopyridine N ,N -Dimethylformamide 4,5-Dimercapto-1,3-dithiole-2-thione Dimethyl Sulfoxide 4,4-Dimethyloxazolidine-1-oxyl 1,1'-Bis(diphenylphosphinoferrocene) Divinylbenzene 3-(3-Dimethylaminopropyl)-1-ethylcarbodiimide Ethylenediaminetetraacetic Acid Ferrocene 1,1,1,3,3,3-Hexamethyldisilazane Hexamethylphosphoric Triamide
HMPT HOAt HOBt MCPBA MEK NBS NCS NIS NMO Pc PCC PDC PEG PG PPTS SDS TBAF TCNQ TEMPO TFA THF THP TMTSF TNBS TPD TTF
Hexamethylphosphorous Triamide 1-Hydroxy-7-azabenzotriazole 1-Hydroxybenzotriazole m -Chloroperoxybenzoic Acid Methyl Ethyl Ketone N -Bromosuccinimide N -Chlorosuccinimide N -Iodosuccinimide 4-Methylmorpholine N -Oxide Phthalocyanine Pyridinium Chlorochromate Pyridinium Dichromate Polyethylene Glycol Prostaglandin Pyridinium p -Toluenesulfonate Sodium Dodecyl Sulfate Tetrabutylammonium Fluoride 7,7,8,8-Tetracyanoquinodimethane 2,2,6,6,-Tetramethylpiperidine 1-Oxyl Trifluoroacetic Acid Tetrahydrofuran Tetrahydropyran Tetramethyltetraselenafluvalene 2,4,6-Trinitrobenzenesulfonic Acid N ,N '-Diphenyl-N ,N '-di(m -tolyl)benzidine Tetrathiafulvalene
AcetylAllyloxycarbonylBenzyltert-ButoxycarbonylBenzoylCarbobenzoxy- (=Benzyloxycarbonyl-) 2,4-Dinitrophenyl(9H-Fluoren-9-ylmethoxy)carbonyl(2-Methoxyethoxy)methyl2,4,6-Trimethylphenyl- (=Mesityl-) MethoxymethylMethanesulfonyl-
Nps Ns PMB SEM TBDMS TES Tf TIPS TMS Tr Ts Z
2-NitrophenylsulfenylNitrobenzenesulfonyl p-Methoxybenzyl 2-(Trimethylsilyl)ethoxymethyltert-Butyldimethylsilyl- (=TBS) TriethylsilylTrifluoromethanesulfonylTriisopropylsilylTrimethylsilylTriphenylmethyl- (=Trityl-) p-Toluenesulfonyl- (=Tosyl) =Cbz
3,5-Di-tert-butyl-4-hydroxytoluene Hydroquinone Hydroquinone Monomethyl Ether (=4-Methoxyphenol)
ONP TBC TBBP
o-Nitrophenol 4-tert-Butylcatechol 3,3',5,5'-Tetra-tert-butyl-4,4'- dihydroxybiphenyl
Protecting Groups / Functional Groups Ac Alloc Bn Boc Bz Cbz Dnp Fmoc MEM Mes MOM Ms
Stabilizers BHT HQ MEHQ
402
Pressure-Temperature Nomograph
●
How to calculate the bp under atmospheric pressure from bp under reduced pressure ①
Connect a degree on the line C and its corresponding bp on the line A under reduced pressure using a straight line. ② An intersection found by step ① on the line B serves as an approximate bp in atmospheric pressure. *This nomograph applies to nonassociated solvent. Since the bp obtained from this nomograph is an approximate value, it is not an exact bp. Reference：Science of Petroleum, Vol.II. p.1281 (1938).
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The physical properties of the typical organic solvents 1) Organic Solvents Methanol (MeOH) Ethanol (EtOH) Propanol (n -PrOH) Isopropyl Alcohol (i -PrOH) Butanol (BuOH) Isobutyl Alcohol (i -BuOH) sec -Butyl Alcohol (s -BuOH) tert -Butyl Alcohol (t -BuOH) Ethylene Glycol 1,2-Dimethoxyethane (Glyme) Diethyl Ether (Et2O) Diisopropyl Ether (i -Pr2O) Acetic Acid (AcOH) Ethyl Acetate (AcOEt) Acetic Anhydride (Ac2O) Tetrahydrofuran (THF) 1,4-Dioxane Acetone Ethyl Methyl Ketone Carbon Tetrachloride (CCl4) Chloroform (CHCl3) Dichloromethane (CH2Cl2) 1,2-Dichloroethane (ClCH2CH2Cl) Benzene (C6H6) Toluene o -Xylene Cyclohexane Pentane Hexane Heptane Acetonitrile (CH3CN) Nitromethane (CH3NO2) Dimethylformamide (DMF) Hexamethylphosphoric Triamide (HMPA) Triethylamine (Et3N) Pyridine (Py) Dimethyl Slufoxide (DMSO) Carbon Disulfide (CS2) a) It doesn't form azeotropic mixture
bp（°C）
mp（°C）
64.5 78.3 97.2 82.2 117.7 107.9 99.5 82.3 197.5 84.5 34.4 68.5 117.9 77.1 140.0 66.0 101.3 56.1 79.6 76.6 61.2 39.6 83.5 80.1 110.6 144.4 80.7 36.1 68.7 98.4 81.6 101.2 153 233 89.6 115.3 189.0 46.2
-97.7 -114.5 -126.2 -88.0 -88.6 -108 -114.7 25.6 -12.6 -69 -116 -85.5 16.7 -83.6 -73.1 -108.4 11.8 -94.7 -86.7 -22.8 -63.5 -94.9 -35.7 5.5 -95.0 -25.2 6.7 -129.7 -95.3 -90.6 -43.8 -28.6 -60.4 7.2 -114.7 -41.6 18.5 -111.6
d（20/4°C）
Compatibility with Water（°C） Miscibility with Waterb) （weight ％ of solvents）
0.791 0.789 0.804 0.785 0.810 0.802 0.807 0.781 1.114 0.869 0.714 0.724 1.050 0.901 1.083 0.889 1.034 0.790 0.805 1.594 1.489 1.326 1.252 0.879 0.867 0.880 0.779 0.626 0.659 0.684 0.782 1.138 0.949 1.027 0.728 0.983 1.100 1.263
ー a) 78.2(96.0) 87.7(71.7) 80.1(88.0) 92.7(57.5) 89.8(67) 87.0(73.2) 79.7(88.2) ー a) 77.4(89.9) 34.2(98.7) 62.2(95.5) ー a) 70.4(91.5)
○ ○ ○ ○ △ △ △ ○ ○ ○ × c) × ○ × c)
63.4(93.3) 87.8(82) ー a) 73.4(88.7) 66(95.9) 56.1(97.8) 38.1(98.5) 72(91.8) 69.3(91.2) 85(79.8) 93.5(50.1) 69.0(91) 34.6(98.6) 61.6(94.4)
○ ○ ○ △ × × × × × × × × × × × ○ × ○ ○ ○ ○ △ ×
76.7(84.2) 83.6(76.4) ー a)
93.6(58.7) ー a) 42.6(97.2)
b) ○：freely miscible △：partially miscible × ：practically immiscible (solubility : less than 1%)
c) highly soluble in water
Example of combination of recrystallization solvents The crystals are obtained from the solution of single or more than one solvent. In the two solvent system, solvent A and B should be miscible : when solubility is A > B, it is desirable that the boiling point is A < B and the density is A > B.
Freezing mixtures Freezing mixtures Ice Ethylene Glycol / CO2 Ice(100) / NH4Cl (25) Ice(100) / NaCl(33) Carbon Tetrachloride / N2 Carbon Tetrachloride / CO2 Ice(100) / EtOH (100) Acetonitrile / N2 Ice(100) / CaCl2 (150)
Temp. （°C） 0 -15 -15 -21 -23 -23 -30 -41 -49
2)
Freezing mixtures Chloroform / N2 Chloroform / CO2 Ethanol / CO2 Ether / CO2 Acetone / CO2 Methanol / N2 n-Pentane / N2 N2
Temp. （°C） -63 -63 -72 -77 -78 -98 -131 -180
References 1）"Yuki Kagaku Jikken no Tebiki 1", editors : T. Goto, T. Shiba, T. Matsuura, Kagaku Dojin 2）"Shinhan Kiso Yuki Kagaku Jikken", K. Hata, K. Watanabe, Maruzen
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⋹८᱂⫳⠽ᡔᴃᓔথ᳝䰤݀ৌ ⋹Ꮦफᓔऎ∈Ϟ࣫䏃߃⼹㢅ು ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖ZZZKRSHELRFRP 㽓࣫ഄऎ ⫬㙗䫊ජ⊍࣪Ꮉѻક᳝䰤݀ৌ ݄ᎲᏖ㽓ऎড়∈࣫䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖JV\LQFKHQJ#\DKRRFQ
݄Ꮂ᯳࣫⾥ᄺҾ఼䆒᳝䰤݀ৌ ⫬㙗ⳕ݄ᎲᏖ㽓ऎᑘ⌾㽓䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖O]E[#YLSVLQDFRP
ढϰഄऎ Ϟ⍋ᅝ䈅⾥ᄺҾ఼᳝䰤݀ৌ Ϟ⍋Ꮦ᭰ೳ䏃 ᓘ ো ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖VKDQSHO#DQSHOFRPFQ
Ϟ⍋㽓ᅱ⫳⠽⾥ᡔ᳝䰤݀ৌ Ϟ⍋Ꮦ⌺ϰᮄऎᓴ∳催⾥ᡔುऎ↩छ䏃 ᓘ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖VDOHV#F[ELRFRP
Ϟ⍋◮吓࣪Ꮉ⾥ᡔ᳝䰤݀ৌ Ϟ⍋Ꮦᕤ∛ऎᎱ䏃 ো োὐ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖LQIR#KDQKRQJJURXSFRP
Ϟ⍋⩲ܝᅲϮ᳝䰤݀ৌ Ϟ⍋Ꮦ⌺ϰᮄऎ㦆ᅝ㽓䏃 ᓘ ᷟ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖LQIR#HQHUJ\FKHPLFDOFRP
Ϟ⍋㣅㧆䖾࣪ᄺ⾥ᡔ᳝䰤݀ৌ Ϟ⍋Ꮦᴼ⌺ऎᅕ䏃 ো䚵∳䰙 $ ᑻ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖RIILFH#LQILQLW\FKHPFRP
Ϟ⍋乡∝࣪Ꮉ⾥ᡔ᳝䰤݀ৌ 䯉㸠ऎ㥬ᴅ䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖]KHQJ[LDRKXL#KRWPDLOFRP
Ϟ⍋᱂߃ྚ࣪ᄺ⾥ᡔ᳝䰤݀ৌ Ϟ⍋Ꮦᴼ⌺ऎӳ䏃 ᓘ ো ᐶ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖\F#SHUFKHPFRP
Ϟ⍋䖜⨲ᇨ࣪ᄺᡔᴃ᳝䰤݀ৌ Ϟ⍋Ꮦ䯉㸠ऎ∳ජ䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖6DOHV #PHU\HUFRP
411
ҧᏖϰℷ䞥៤࣪Ꮉ᳝䰤݀ৌ ҧᏖ䚥㽓䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖WFG]#FRP
फҀ吣࣪⦏Ҿ఼᳝䰤݀ৌ फҀᏖᑇफ䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖QMSFKE#FRP
ᵁᎲᐌ䴦࣪Ꮉ᳝䰤݀ৌ ᵁᎲᏖ㡂ቅ㽓䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖MLQOLXSLQ#FRP
फҀᇓᖋ䆩偠఼ᴤ᳝䰤݀ৌ फҀᏖ⥘℺ऎスि䏃 ো ᐶ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖QMVKRXGH#FRP
ढϰए㥃㙵ӑ᳝䰤݀ৌ఼ᴤ࣪ࠖߚ݀ৌ ᵁᎲᏖ⏙⋄㸫 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖VKHQPLKXD#FRP
㢣ᎲᎹϮುऎम㕢䖒䆩ࠖҾ఼᳝䰤݀ৌ 㢣ᎲᎹϮುऎ᯳㸫 ো⫳⠽㒇㉇ು $ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖[XMLDQ#ERPHLGDFRP
ᵁᎲᓎ∛࣪Ꮉ᳝䰤݀ৌ ⌭∳ⳕᵁᎲᏖḤᑤওḤ৯㸫䘧ᑓഎ䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖ #TTFRP
ᯚቅডᑨ䫒࣪Ꮉ఼ᴤ᳝䰤݀ৌ ᯚቅᏖᯚ࣫䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖I\OEI#FRP
⏽ᎲᏖ呓ජ䞥ቅ࣪ᄺ䆩ࠖҾ఼݀ৌ ⏽ᎲᏖ⠯ቅ࣫䏃 ো࣪ᎹᏖഎ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖Z]MLQVKDQ#TTFRP
᮴䫵Ёᘦᅲ偠Ҿ఼᳝䰤݀ৌ ᮴䫵Ꮦ䫵≾㽓䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖Z[]K\T#FRP
ᅕ⊶༹म⾥ᄺҾ఼᳝䰤݀ৌ ᅕ⊶Ꮦ∳ϰऎ∳ϰ࣫䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖/5#QE\TZFRP
ড়㙹䞥߯ᮄᴤ᳝᭭䰤݀ৌ ড়㙹Ꮦᅬҁ䏃 োᯎජॺ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖[VP #VRKXFRP
ᅕ⊶Ꮦ⍋Ჭᮄ␃఼࣪䌌ᯧ᳝䰤݀ৌ ᅕ⊶Ꮦṕ㸫 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖ #TTFRP
ড়㙹㕢Є࣪ᎹҾ఼᳝䰤݀ৌ ড়㙹Ꮦ▝⑾ϰ䏃݄ҁುଚ䫎 ᐶ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖ #FRP
फҀᰮ᱈࣪⦏Ҿ఼᳝䰤݀ৌ 哧ὐऎ啭ҧᏋ ো䮼䴶᠓ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖QMZDQTLQJ#FRP
फᯠ㓓ᘦ⾥ᡔ᳝䰤݀ৌ फᯠᏖ乎䏃 ো᱃⊇᯳ᅿ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖QFJH#FRP
फҀᒋ⒵ᵫ࣪ᎹᅲϮ᳝䰤݀ৌ फҀᏖЁቅ࣫䏃 ো啭৳ᑓഎ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖VDOHV#FKHPOLQFRPFQ
∳㽓ⳕϰᮍ࣪⦏䆒᳝䰤݀ৌ फᯠᏖफҀ㽓䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖QFGIKJ#FRP
412
⚳ৄҎ㒣䌌᳝䰤݀ৌ ⚳ৄᏖ㡱㔬ऎᓎ䆒䏃 ো䌌ὐ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖WDQJUHQMLQJPDR#FRP
䴦ቯ㝒啭ᖂ⊶⾥ᡔ᳝䰤݀ৌ 䴦ቯᏖ䖑ᅕ䏃 ো乤Ё䫊㸫佪ᑻ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖VDOHV#WOZEFRPFQ
䴦ቯ䨿ᒋᮃᖋ⫳⠽ଚ䌌᳝䰤݀ৌ 䴦ቯᏖಯᮍऎҎ⇥䏃 ো ऩ ܗᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖]KDQJ[XH\DQ #FRP
⌢फᳱᯁҾ఼䆒᳝䰤݀ৌ ⌢फᏖग़ජऎ㢅ು䏃 ো োὐ䰘ሲ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖GLQJ[T#VLQDFRP
Ёफഄऎ ℺∝⬇䆩࣪Ꮉ⾥ᡔ᳝䰤݀ৌ ℺ᯠऎϕᄫḹ䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖ZKVVKJBMNO#FRP
ᑓᎲᏖ䞥ढ࣪ᄺ䆩᳝ࠖ䰤݀ৌ ᑓᎲᏖ⍋⦴ऎ∳➩फ䏃 োড়߽থሩॺ ὐ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖VHUYLFH#MLQKXDGDFRP
⏅ഇᏖ࣪䆩⾥ᡔ᳝䰤݀ৌ ⏅ഇᏖफቅऎϔ⬆ϰᮍᮄഄ $ ᑻ োଚ䫎 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖+VVFLHQFH#KVVFLHQFHFRP 㽓फഄऎ 䞡ᑚ㽓फ࣪ᄺ䆩᳝ࠖ䰤݀ৌ 䞡ᑚ䕗എষ % 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖;QKV#\DKRRFQ
ᯚᯢס᥋⾥ᡔ᳝䰤݀ৌ ᯚᯢᏖᓎ䆒䏃㖹㸫 োᴹᮄජ ᐶ ᅸ 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖LQIR#ELRJHQQHWFQ
㓉䰇Ꮦ㤷ⲯ⾥ᡔ᳝䰤݀ৌ 㓉䰇ᏖЈು䏃㽓↉ ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖ #FRP
៤䛑Ꮦ㢠䪆࣪⦏᳝䰤݀ৌ ៤䛑Ꮦ啭㟳䏃 ো 䚂㓪˖ ⬉䆱˖ Ӵⳳ˖ 䚂ӊ˖ #TTFRP
413
Reagent Guide
Synthetic Organic Chemistry & Materials Chemistry Not for Sale First Edition : May 2011
Publisher
TOKYO CHEMICAL INDUSTRY CO., LTD. Global Business Department 4-10-2, Nihonbashi-Honcho, Chuo-Ku, Tokyo 103-0023, Japan
Editor
TOKYO CHEMICAL INDUSTRY CO., LTD. Technical Information Management Department
©2011 Tokyo Chemical Industry Co., Ltd. Reproduction forbidden without permission. Printed in Japan
T190110530
