QUALITY OF LIFE THROUGH QUALITY OF INFORMATION

QUALITY OF LIFE THROUGH QUALITY OF INFORMATION Studies in Health Technology and Informatics This book series was started in 1990 to promote research...
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QUALITY OF LIFE THROUGH QUALITY OF INFORMATION

Studies in Health Technology and Informatics This book series was started in 1990 to promote research conducted under the auspices of the EC programmes’ Advanced Informatics in Medicine (AIM) and Biomedical and Health Research (BHR) bioengineering branch. A driving aspect of international health informatics is that telecommunication technology, rehabilitative technology, intelligent home technology and many other components are moving together and form one integrated world of information and communication media. The series has been accepted by MEDLINE/PubMed, SciVerse Scopus, EMCare, Book Citation Index – Science and Thomson Reuters’ Conference Proceedings Citation Index. Series Editors: Dr. O. Bodenreider, Dr. J.P. Christensen, Prof. G. de Moor, Prof. A. Famili, Dr. U. Fors, Prof. A. Hasman, Prof. E.J.S. Hovenga, Prof. L. Hunter, Dr. I. Iakovidis, Dr. Z. Kolitsi, Mr. O. Le Dour, Dr. A. Lymberis, Prof. J. Mantas, Prof. M.A. Musen, Prof. P.F. Niederer, Prof. A. Pedotti, Prof. O. Rienhoff, Prof. F.H. Roger France, Dr. N. Rossing, Prof. N. Saranummi, Dr. E.R. Siegel, Prof. T. Solomonides and Dr. P. Wilson

Volume 180 Recently published in this series Vol. 179. M. García-Rojo, B. Blobel and A. Laurinavicius (Eds.), Perspectives on Digital Pathology – Results of the COST Action IC0604 EURO-TELEPATH Vol. 178. A.J. Maeder and F.J. Martin-Sanchez (Eds.), Health Informatics: Building a Healthcare Future Through Trusted Information – Selected Papers from the 20th Australian National Health Informatics Conference (HIC 2012) Vol. 177. B. Blobel, P. Pharow and F. Sousa (Eds.), pHealth 2012 – Proceedings of the 9th International Conference on Wearable Micro and Nano Technologies for Personalized Health Vol. 176. T. Kotwicki and T.B. Grivas (Eds.), Research into Spinal Deformities 8 Vol. 175. S. Gesing, T. Glatard, J. Krüger, S.D. Olabarriaga, T. Solomonides, J.C. Silverstein, J. Montagnat, A. Gaignard and D. Krefting (Eds.), HealthGrid Applications and Technologies Meet Science Gateways for Life Sciences Vol. 174. B. Blobel, R. Engelbrecht and M.A. Shifrin (Eds.), Large Scale Projects in eHealth – Partnership in Modernization – Proceedings of the EFMI Special Topic Conference, 18–20 April 2012, Moscow, Russia Vol. 173. J.D. Westwood, S.W. Westwood, L. Felländer-Tsai, R.S. Haluck, R.A. Robb, S. Senger and K.G. Vosburgh (Eds.), Medicine Meets Virtual Reality 19 – NextMed Vol. 172. Y. Quintana, A. Van Kirk Villalobos and D. May (Eds.), Advancing Cancer Education and Healthy Living in Our Communities – Putting Visions and Innovations into Action – Selected Papers from the Cure4Kids® Global Summit 2011

ISSN 0926-9630 (print) ISSN 1879-8365 (online)

Q Quality y of Liife through Qualit Q ty of In nformaation Proceed dings of MIE2012 M

Edited by y

Jo ohn Manttas Health Inforrmatics Labo oratory, Univversity of Ath hens, Greecee Chair of the Scieentific Programme Comm mittee

Stig Kjær K And dersen Departm ment of Healtth Science an nd Technolog gy, Aalborg University, D Denmark

Maria Crristina Mazzoleni M i Salvato ore Maugeri Foundation, F IRCCS, Pavvia, Italy

Beernd Blob bel eheallth Competen nce Center, University U Hospital H Regeensburg, Gerrmany

Silv vana Quaglini B Biomedical I Informatics L Laboratory, University of Pavia, Italyy

and

A Anne Moeen Institute off Health and Society, Uniiversity of Osslo, Norway

Amstterdam • Berrlin • Tokyo • Washington, DC

© 2012 European Federation for Medical Informatics and IOS Press. All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without prior written permission from the publisher. ISBN 978-1-61499-100-7 (print) ISBN 978-1-61499-101-4 (online) Library of Congress Control Number: 2012945494 Publisher IOS Press BV Nieuwe Hemweg 6B 1013 BG Amsterdam Netherlands fax: +31 20 687 0019 e-mail: [email protected] Distributor in the USA and Canada IOS Press, Inc. 4502 Rachael Manor Drive Fairfax, VA 22032 USA fax: +1 703 323 3668 e-mail: [email protected]

LEGAL NOTICE The publisher is not responsible for the use which might be made of the following information. PRINTED IN THE NETHERLANDS

Quality of Life through Quality of Information J. Mantas et al. (Eds.) IOS Press, 2012 © 2012 European Federation for Medical Informatics and IOS Press. All rights reserved.

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Preface The theme of MIE2012 is ‘Quality of Life through Quality of Information’. The importance of Information towards Quality of Health Care and Quality of Life is highlighted across the current proceedings. The 24th Medical Informatics in Europe Conference (MIE2012) has been organised by the European Federation for Medical Informatics (EFMI) with the collaboration of the Italian Medical Informatics Association (AIIM) and the Italian e-health Community, and takes place in the historical city of Pisa, Italy from 26th to 29th of August, 2012. EFMI is a federation of national medical informatics associations from 32 European countries, and its purpose is to develop and disseminate knowledge and expertise in the field of biomedical and health informatics. Besides the national associations, the working groups, which include experts in specialist fields ranging from electronic patient records, medical imaging, and evaluation to nursing and rehabilitation, are the main channel through which new knowledge and ideas are developed and disseminated. Because EFMI understands the role which application and implementation plays, a third pillar has been introduced to the federation, that of the Institutional Members, such as industries, academic institutions and organisations. The conference is being held in Pisa, a city well known not only for its famous leaning tower, but also as the birthplace of Galileo Galilei, who some consider to be the father of modern science. He was responsible for introducing the notion of experimental proof into scientific research. It is this approach which is, without any doubt, crucial to our research in medical informatics. We need evidence before we can apply our knowledge to health care; evidence-based medicine needs quality information in order to lead to quality of health, and thus to quality of life. The conference focuses on the role of e-health in pursuing benefits in terms of quality of life for patients, health-care personnel, citizens and society. The topic can be analysed from many points of view, and MIE2012 provides a unique platform for the fruitful exchange of ideas and experiences among the actors and stakeholders of ICT supported healthcare. Both methodologies and examples of applications form the basis for the discussion, and all of us will learn, not only from success stories in the field, but also from failures. The opinion and experiences of the designers and planners, as well as those of users, are of great importance when the target is the global improvement of quality of life, at both personal and public level. For this reason we encourage health professionals, policy makers and also patients and citizens’ associations to take an active part in the conference and share their knowledge. The present volume incorporates contributions related to the latest achievements in biomedical and health informatics in terms of major challenges such as interoperability, collaboration, coordination, and increasingly, patient oriented health care at the most appropriate level of care. The papers also provide new perspectives for the future of biomedical and health informatics, critical appraisals of strategies for user involvement, insights for design, deployment, and sustainable use of electronic health records, standards, social software, citizen centred e-health, and new challenges in rehabilitation

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and social care informatics, where health professionals collaborate in teams with colleagues and with their patients. MIE2012 also introduces the ‘Village of the Future’; a vibrant agora where national, regional and European projects, as well as other initiatives, present, demonstrate, discuss and share ideas and innovations in the ‘eLounge’, creating new coalitions for the future. The village provides an opportunity to get involved in presentations, demonstrations, and living poster and collaborative sessions. The village is open to all ‘citizens’, with a focus on the younger generation, who can present new initiatives and results. In particular, presentations will be based on technologies such as the semantic web, social media and web 2.0/3.0, which contribute to new ways of delivering healthcare and facilitating a higher quality of life for citizens, patients and health professionals alike. The presentations form part of the electronic version of the proceedings, and are not included in the current volume. The Scientific Programme Committee of MIE2012 received 449 submissions. The selection process presented a major challenge for the SPC. Almost all submissions were reviewed by three reviewers. The reviews were accompanied by suggestions and advice for possible improvements to the contribution. In case of conflicting opinions, the SPC appointed additional reviewers. We are indebted to the 205 colleagues who volunteered their time and energy to be involved in this peer review processes, which necessitated 1,077 individual reviews. The reviewers are listed in the appendix as a token of our appreciation for their effort and dedication. The programme for MIE2012 consists of 206 oral presentations of full papers, 48 posters, 25 short communication oral presentations, 26 short communication posters, 11 workshops, 2 EFMI WG workshops, 6 tutorials, and 2 panels. It is encouraging that so many of the submissions are from young researchers, and we are pleased that MIE2012 provides an arena where they can begin to exchange their ideas and findings with their peers. Furthermore, MIE2012 hosts an application oriented track, the ‘Village of the Future’, where EFMI institutional members and corporate affiliates can discuss pressing issues and innovations headed for the market, and where the latter will also be demonstrated. Most of the topics presented at MIE2012 are interdisciplinary in nature and of interest to a variety of professionals: physicians, nurses, and allied health providers, health informaticians, engineers, academics and representatives from industry and consultancy in the various fields. This European conference commands an international audience, gathering participants from most parts of the world. This is reflected by the nationalities of the 1,016 contributing authors, originating from 43 countries in Europe, the Middle East, Asia and Africa, as well as South and North America. Conference proceedings consist of a printed version and an electronic version, and are considered to be an integral part of MIE2012. The printed version includes full papers accepted for presentation as well as posters, and all are indexed in Medline. The CD version of the proceedings includes the full papers, posters, short communications, workshops, tutorials, panels, and a synopsis of the ‘Village of the Future’. The CD is an EFMI publication, which will also be available online at www.EFMI.org after a period agreed with the publisher. We are grateful to the colleagues who served as members of the executive SPC, and to the affiliate, Dr. Dimitrios Zikos. We would also like to express our thanks to Drs. Jacob Hofdijk and Dr. Christian Lovis for coordinating the ‘Village of the Future’.

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Thanks also to Professor Jana Zvarova for chairing the subcommittee for workshop and panel selection. Finally, we take this opportunity to thank the members of the award committees for the Peter Reichertz Prize, awarded for the best paper by a young scientist; the Rolf Hansen Prize for the best paper on a clinical information system; and the poster prize for the best poster. John Mantas Stig Kjær Andersen Maria Cristina Mazzoleni Bernd Blobel Silvana Quaglini Anne Moen Pisa, 25/06/2012

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Reviewers for MIE2012 Abidi, Samina Abidi, Syed Sibte Raza Adams, Samantha Akbasoglu (Kaymakoglu), Beyza Alpay, Laurence Alsafadi, Yasser Anguita, Alberto Atreja, Ashish Auma, Kennedy Balbinot, Alexandre Bamidis, Panagiotis Barbosa, Sayonara Bellika, Johan Gustav Ben Said, Mohamed Bernad, Elena Beuscart, Regis Beuscart-Zephir, Marie-Catherine Borycki, Elizabeth Boye, Niels Bratan, Tanja Breil, Bernhard Bringay, Sandra Brochhausen, Mathias Brooks, Ian Bygholm, Ann Cabitza, Federico Ceusters, Werner Chae, Young Moon Cheshire, Paul Chronaki, Catherine Cimino, James Costa, Carlos Courteille, Olivier Cummings, Elizabeth Curk, Tomaz Daskalakis, Stylianos Day, Karen de Bruijn, Berry De Clercq, Etienne de Keizer, Nicolette de la Calle, Guillermo de la Harpe, Retha Deserno, né Lehmann, Thomas M.

Dexheimer, Judith Dias, Andre Donaldson, Paul Douali, Nassim Eccher, Claudio Effken, Judith Eisenstein, Eric Elberg, Pia Epping, Paul Fagan, Lawrence Feria, Rommel Fernandez-Breis, Jesualdo Tomas Fioriglio, Gianluigi Focsa, Mircea Forkert, Nils Daniel Fox, Scott Fritz, Fleur Frize, Monique Fuchsberger, Christian Gamberger, Dragan Garde, Sebastian Gardner, Reed Georg, Gersende Georgiou, Andrew Giacomini, Mauro Gibaud, bernard Grabar, Natalia Grain, Heather Grandison, Tyrone Hackl, Werner O. Hagglund, Maria Hains, Isla Hammond, Ed Hanmer, Lyn Hansen, David Hartvigsen, Gunnar Haskell, Robert Haux, Reinhold Heinzl, Harald Héja, Gergely Holzmüller-Laue, Silke Hristovski, Dimitar Hsueh, Pei-Yun Sabrina

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Huser, Vojtech Iancu, Miron Ingenerf, Josef Iriso, Santiago James, Andrew Jao, Chiang Jaspers, Monique Jones, Josette Juhola, Martti Kaiser, Katharina Karanikolas, Nikitas Karopka, Thomas Katt, Basel Kindler, Hauke Klein, Gunnar O. Knaup, Petra Koufi, Vassiliki Koutkias, Vassilis Kusnierczyk, Waclaw Lærum, Hallvard Laforest, Frederique Lahtela, Antti Landmark, Andreas D. Layzell, Brian Lim Choi Keung, Sarah Lippert, Søren Lopez, Diego Lovis, Christian Lungeanu, Diana Magrabi, Farah Majeed, Raphael W. Mayer, Miguel Angel McClay, James Mohd Yusof, Maryati Mohyuddin, Mohyuddin Montani, Stefania Mueller, Henning Müller, Marcel Müller, Thomas Murray, Peter Muteba Ayumba, Eustache Mykkänen, Juha Niggemann, Joerg Nøhr, Christian Oemig, Frank Oliveira, Jose Luis Onken, Michael Orel, Andrej Otero, Paula

Pape-Haugaard, Louise Parry, Dave Pearl, Adrian Peek, Niels Pelayo, Sylvia Peleg, Mor Petkovic, Milan Petrovecki, Mladen Portet, François Portinale, Luigi Protti, Denis Punys, Vytenis Purnat, Tina D. Razavi, Amir-Reza Richards, Janise Rindflesch, Thomas Roberts, Jean Roderer, Nancy Rognoni, Carla Röhrig, Rainer Romacker, Martin Rosenbeck, Kirstine Rossing, Niels Ruotsalainen, Pekka Saboor, Samrend Sacchi, Lucia Saliez, Etienne Santos, Raquel Sara, Antony Schabetsberger, Thomas Schmidt, Rainer Sedlmayr, Martin Seroussi, Brigitte Shahsavar, Nosrat Shaw, Nicola (Nikki) Showell, Chris Silveira, Denise Skrøvseth, Stein Olav Smalheiser, Neil Staemmler, Martin Stausberg, Jürgen Stenzhorn, Holger Stern, Milton Stoicu-Tivadar, Lacramioara Supek, Selma Talmon, Jan ten Teije, Annette Tirmizi, Suha Toyoda, Shuichi

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Tsiknakis, Manolis Tusch, Guenter van Engen-Verheul, Mariëtte Vimarlund, Vivian Vincent, Doug Wang, Dongwen Weltner, János Welzer, Tatjana Wilbacher, Ingrid

Witte, Herbert Wolf, Klaus-Hendrik Woolman, Paul Zai, Adrian Zary, Nabil Zayim, Neşe Zhang, Songmao Zikos, Dimitris

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Contents Preface John Mantas, Stig Kjær Andersen, Maria Cristina Mazzoleni, Bernd Blobel, Silvana Quaglini and Anne Moen Reviewers for MIE2012

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Keynotes Challenges of the e-Health Curricular Education in Bio-Medical Engineering and in Medicine Francesco Pinciroli, Stefano Bonacina, Sara Marceglia, Simona Ferrante and Luca Mazzola Personal Health Records Finn Kensing Enhancing Service Delivering, Improving Quality of Life, Preserving Independence Through Assistive Technology Roberta Annicchiarico The Future of Biomedical Informatics: A Perspective from Academia Edward H. Shortliffe Improving Quality of Life Through eHealth – The Patient Perspective Sabine Koch

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14 19 25

Methodologies for Information Quality Conceptual Modeling for Prospective Health Technology Assessment Marion Gantner-Bär, Anatoli Djanatliev, Hans-Ulrich Prokosch and Martin Sedlmayr Data Definition Ontology for Clinical Data Integration and Querying Ariane Assele Kama, Audi Primadhanty, Rémy Choquet, Douglas Teodoro, Frank Enders, Catherine Duclos and Marie-Christine Jaulent Migration Path for Structured Documentation Systems Including Standardized Medical Device Data Ann-Kristin Kock, Josef Ingenerf, Stoyan Halkaliev and Heinz Handels Quality Requirements for EHR Archetypes Dipak Kalra, Archana Tapuria, Tony Austin and Georges De Moor Using Archetypes for Defining CDA Templates David Moner, Alberto Moreno, José A. Maldonado, Montserrat Robles and Carlos Parra Using Enterprise Ontology for Improving Emergency Management in Hospitals David Galego Dias, Luís Velez Lapão and Miguel Mira da Silva A ClaML-Based Interface for the Import of Monohierarchical Classifications Sylvie Mn Ngouongo and Jürgen Stausberg

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58 63

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An Information Artifact Ontology Perspective on Data Collections and Associated Representational Artifacts Werner Ceusters Automatic Generation of MedDRA Terms Groupings Using an Ontology Gunnar Declerck, Cédric Bousquet and Marie-Christine Jaulent Formal Specification of an Ontology-Based Service for EHR Interoperability Carolina González, Bernd G.M.E. Blobel and Diego M. López Mapping SNOMED CT to ICD-10 Kathy Giannangelo and Jane Millar Rare Diseases Knowledge Management: The Contribution of Proximity Measurements in OntoOrpha and OMIM X. Aimé, J. Charlet, F. Furst, P. Kuntz, F. Trichet and F. Dhombres Design of an Original Interface That Facilitates the Use of Clinical Practice Guidelines of Infection by Physicians in Primary Care Rosy Tsopra, Jean-Baptiste Lamy, Alain Venot and Catherine Duclos Knowledge Representation for Fuzzy Inference Aided Medical Image Interpretation Norbert Gal and Vasile Stoicu-Tivadar MRI Image Artifact Ontology: A Proposed Method for Improved Recognition Jeremy Lasbleiz, John Morelli, Nicolas Schnel, Anita Burgun, Régis Duvauferrier and Hervé Saint Jalmes Ontology Driven Decision Support Systems for Medical Diagnosis Valéry Donfack Guefack, Valérie Bertaud Gounot, Régis Duvauferrier, Annabel Bourde, John Morelli and Jérémy Lasbleiz The Reproducibility of CLIF, a Method for Clinical Quality Indicator Formalisation Kathrin Dentler, Ronald Cornet, Annette ten Teije, Kristien Tytgat, Jean Klinkenbijl and Nicolette de Keizer Virtual Medical Record Implementation for Enhancing Clinical Decision Support Valentin-Sergiu Gomoi, Daniel Dragu and Vasile Stoicu-Tivadar An Application of Symbolic Dynamics for FHRV Assessment Mario Cesarelli, Maria Romano, Paolo Bifulco, Gianni Improta and Gianni D’Addio Automated Versus Interactive Spectral Analysis of Heart Rate Variability from 24-Hour Holter Recordings in Heart Failure Patients Roberto Maestri, Maria Teresa La Rovere and Gian Domenico Pinna Probabilistic Graphical Models for Effective Connectivity Extraction in the Brain Using fMRI Data Mohammad Ali Safari and Majid Mohammadbeigi Scale-Space Methods for Live Processing of Sensor Data Stein Olav Skrøvseth, André Dias, Lukas Gorzelniak, Fred Godtliebsen and Alexander Horsch Segmentation of Crohn, Lymphangiectasia, Xanthoma, Lymphoid Hyperplasia and Stenosis Diseases in WCE Omid Haji-Maghsoudi, A. Talebpour, H. Soltanian-Zadeh and N. Haji-Maghsoodi

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Generation of a Probabilistic Arterial Cerebrovascular Atlas Derived from 700 Time-of-Flight MRA Datasets Nils Daniel Forkert, Santiago Suniaga, Jens Fiehler, Heike Wersching, Stefan Knecht and Andre Kemmling Customization of Biomedical Terminologies Julien Homo, Laëtitia Dupuch, Allel Benbrahim, Natalia Grabar and Marie Dupuch IRMA Code II: Unique Annotation of Medical Images for Access and Retrieval Tim-Christian Piesch, Henning Müller, Christiane K. Kuhl and Thomas M. Deserno Method for Mapping the French CCAM Terminology to the UMLS Metathesaurus Cédric Bousquet, Julien Souvignet, Tayeb Merabti, Eric Sadou, Béatrice Trombert and Jean-Marie Rodrigues Semantic Relations of Binary Compounds Annotated with SNOMED CT Dimitrios Kokkinakis The Issue of Building Generative Terminologies for Automatic Medical Data Aggregation Ihssen Belhadj, Jêrome Nobecourt, Sylvie Despres and Christian Jacquelinet Towards a Bilingual Alzheimer’s Disease Terminology Acquisition Using a Parallel Corpus Khadim Drame, Gayo Diallo and Fleur Mougin An Ontological Approach to Manage and Harmonize Document Types Frank Oemig and Bernd Blobel Patient Support ICT Tool for Hypertension Monitoring Morten Algy Bonderup, Stine Veje Hangaard, Pernille Heyckendorff Lilholt, Mette Dencker Johansen and Ole K. Hejlesen RAVEL: Retrieval and Visualization in ELectronic Health Records Frantz Thiessard, Fleur Mougin, Gayo Diallo, Vianney Jouhet, Sébastien Cossin, Nicolas Garcelon, Boris Campillo, Wassim Jouini, Julien Grosjean, Philippe Massari, Nicolas Griffon, Marie Dupuch, Fayssal Tayalati, Edwige Dugas, Antonio Balvet, Natalia Grabar, Suzanne Pereira, Bruno Frandji, Stefan Darmoni and Marc Cuggia Standard Based Multiclient Medical Data Visualization Georgy Kopanitsa An Advanced Search Engine for Patent Analytics in Medicinal Chemistry Emilie Pasche, Julien Gobeill, Douglas Teodoro, Arnaud Gaudinat, Dina Vishnyakova, Christian Lovis and Patrick Ruch Classification and Prioritization of Biomedical Literature for the Comparative Toxicogenomics Database Dina Vishnyakova, Emilie Pasche, Julien Gobeill, Arnaud Gaudinat, Christian Lovis and Patrick Ruch CliniQA: Highly Reliable Clinical Question Answering System Yuan Ni, Huijia Zhu, Peng Cai, Lei Zhang, Zhaoming Qui and Feng Cao Development and Representation of Health Indicators with Thematic Maps Simona Dalle Carbonare, Carlo Cerra and Riccardo Bellazzi

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Efficient Medical Information Retrieval in Encrypted Electronic Health Records Cédric Pruski and François Wisniewski The Use of Linked Registries to Assess Long-Term Mortality of ICU Patients Sylvia Brinkman, Evert de Jonge, Ameen Abu-Hanna, Dylan W. de Lange and Nicolette F. de Keizer Grouping the Pharmacovigilance Terms with a Hybrid Approach Marie Dupuch, Laëtitia Dupuch, Amandine Perinet, Thierry Hamon and Natalia Grabar Information Extraction from SMS Text Related to a Reminder Service for Outpatients Stefania Rubrichi, Stéphanie Eku Ndam, Andrea Battistotti and Silvana Quaglini Inventory of Tools for Dutch Clinical Language Processing Ronald Cornet, Armand van Eldik and Nicolette de Keizer Linguistic Analysis of Large-Scale Medical Incident Reports for Patient Safety Katsuhide Fujita, Masanori Akiyama, Keunsik Park, Etsuko (Nakagami) Yamaguchi and Hiroyuki Furukawa Measuring Lexical Similarity Methods for Textual Mapping in Nursing Diagnoses in Spanish and SNOMED-CT Jorge Cruanes, M. Teresa Romá-Ferri and Elena Lloret A “Meta”-Perspective on “Bit Rot” of Biomedical Research Data Frank Dickmann, Romanus Grütz and Otto Rienhoff A Semantic Approach for Digital Long-Term Preservation of Electronic Health Documents Stephan Kiefer, Michael Schäfer and Jochen Rauch Automated Realtime Data Import for the i2b2 Clinical Data Warehouse: Introducing the HL7 ETL Cell Raphael W. Majeed and Rainer Röhrig Coupling K-Nearest Neighbors with Logistic Regression in Case-Based Reasoning Boris Campillo-Gimenez, Sahar Bayat and Marc Cuggia Flexible Solution for Interoperable Cloud Healthcare Systems Mihaela Marcella Vida, Oana Sorina Lupşe, Lăcrămioara Stoicu-Tivadar and Elena Bernad TEDIS, Pervasive Developmental Disorder’ Patients Information System, Preliminary Results Mohamed Ben Said, Laurence Robel, Marie Pellegrin-Touati, Berangere Rousselot-Pailly, Bernard Golse, Jean Philippe Jais and Paul Landais Characteristics of Patients at Risk for Adverse Drug Events: Designing for Patient Safety and Decision Support Elizabeth Borycki, Jeff Barnett, Susan Walisser, Paule Bellwood, Melissa Clarke and David Greig Clinical Diagnosis Support System Based on Case Based Fuzzy Cognitive Maps and Semantic Web Nassim Douali, Jos De Roo and Marie-Christine Jaulent

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Comparing Drools and Ontology Reasoning Approaches for Telecardiology Decision Support Pascal Van Hille, Julie Jacques, Julien Taillard, Arnaud Rosier, David Delerue, Anita Burgun and Olivier Dameron Decision Support in Trauma Management: Predicting Potential Cases of Ventilator Associated Pneumonia Adrian Pearl and David Bar-Or Knowledge-Based Tacrolimus Therapy for Kidney Transplant Patients Walter Seeling, Max Plischke and Christian Schuh Proposal of Diagnostic Process Model for Computer Based Diagnosis Yasushi Matsumura, Toshihiro Takeda, Shiro Manabe, Hirokazu Saito, Kei Teramoto, Shigeki Kuwata and Naoki Mihara

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Quality Through Evaluation Challenges in Evaluating Telehealth Through RCT-The Problem of Randomization Urvashi Sharma, Julie Reed, Cathal Doyle and Derek Bell eHealth Indicators: Results of an Expert Workshop Hannele Hyppönen, Elske Ammenwerth, Christian Nohr, Arild Faxvaag and Åke Walldius eHealth Interoperability Evaluation Using a Maturity Model Wded Guédria, Hanan Bouzid, Guido Bosh, Yannick Naudet and David Chen Exploring a Methodology for eHealth Indicator Development Hannele Hyppönen, Elske Ammenwerth and Nicolet de Keizer Population-Based Clinical Decision Support: A Clinical and Economic Evaluation Eric L. Eisenstein, Kevin J. Anstrom, Rex Edwards, Janese M. Willis, Jessica Simo and David F. Lobach Quality Assurance and Effectiveness of the Medication Process Through Tablet Computers? Amanda Buus, Louise Nyvang, Sisse Heiden and Louise Pape-Haugaard A Framework for User Involvement and Context in the Design and Development of Safe e-Health Systems Andre Kushniruk and Paul Turner Analysis of Metrics for the Usability Evaluation of EHR Management Systems Georgy Kopanitsa, Zhanna Tsvetkova and Hasan Veseli Low-Cost Rapid Usability Testing for Health Information Systems: Is It Worth the Effort? Tristin B. Baylis, Andre W. Kushniruk and Elizabeth M. Borycki Patient Safety-Oriented Usability Testing: A Pilot Study Romaric Marcilly, Stephanie Bernonville, Costanza Riccioli and Marie-Catherine Beuscart-Zephir The Role of Simulation in Clinical Information Systems Development Sanne Jensen, Karen Marie Lyng and Christian Nøhr Using Video Observation to Gain Insight into Complex Clinical Work Practices Anna Marie Balling Hostgaard and Pernille Bertelsen

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ICU Nurses’ Evaluations of Integrated Information Displays on User Satisfaction and Perceived Mental Workload Sven H. Koch, Dwayne Westenskow, Charlene Weir, Jim Agutter, Maral Haar, Matthias Görges, David Liu and Nancy Staggers Proactive Authenticated Notifications for Health Practitioners: Two Way Human Computer Interaction Through Phone Raphael W. Majeed, Mark R. Stöhr and Rainer Röhrig Small Cause – Big Effect: Improvement in Interface Design Results in Improved Data Quality – A Multicenter Crossover Study Janko Ahlbrandt, Michael Henrich, Bernd A. Hartmann, Bettina B. Bundschuh, Julia Schwarz, Joachim Klasen and Rainer Röhrig The Use and Usability of EPR Systems in Oncology Thomas Poulter and Peter A. Bath Usability Evaluation of a Guideline Implementation System for Cardiac Rehabilitation: Think Aloud Study Mariëtte van Engen-Verheul, Linda Peute, Ellen Kilsdonk, Niels Peek and Monique Jaspers

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Quality of Care Delivery Process A Semantic Wiki for Editing and Sharing Decision Guidelines in Oncology Thomas Meilender, Jean Lieber, Fabien Palomares, Gilles Herengt and Nicolas Jay An Engine for Compliance Checking of Clinical Guidelines Jing Mei, Haifeng Liu, Guotong Xie and Geetika T. Lakshmanan Application of the Logical Elements Rule Method for Formalization of Clinical Rules: Case Study of ACOVE-NLI Stephanie Medlock, Saeid Eslami, Dedan Opondo, Marjan Askari, Sophia de Rooij and Ameen Abu-Hanna Clinical Guideline Representation in a CDS: A Human Information Processing Method Ellen Kilsdonk, Rinke Riezebos, Leontien Kremer, Linda Peute and Monique Jaspers Computerized Clinical Guidelines: Current Status & Principles for Future Research Haridimos Kondylakis and Manolis Tsiknakis Ontology-Based Computerization of Acute Coronary Syndrome Clinical Guideline for Decision Support in the Emergency Department Mostafa Omaish, Samina Abidi and Syed Sibte Raza Abidi A Semiotic View on Paper and Mobile Care Data Quality Retha De La Harpe Challenges and Issues of Geolocation in Clinical Environment David-Zacharie Issom, Claire Hagry, Laetitia Wodia Mendo, Henry Seng, Frederic Ehrler and Christian Lovis Empower the Patients with a Dialogue-Based Web Application Charlotte D. Bjørnes, Elizabeth Cummings and Christian Nøhr From Clinical Requirement to Personalized Wellness Decision Support: A Data-Driven Framework for Computer-Supported Guideline Refinement Pei-Yun Hsueh, Ci-Wei Lan, Vincent Deng and Xinxin Zhu

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Interoperability Design of Personal Health Information Import Service Mika Tuomainen and Juha Mykkänen Using a Patient-Centered Approach for Health and Social Care Integration Mikaela Poulymenopoulou, Despoina Papakonstantinou, Flora Malamateniou and George Vassilacopoulos Accuracy of Clinical Data Entry when Using a Computerized Decision Support System: A Case Study with OncoDoc2 Brigitte Séroussi, Brigitte Blaszka-Jaulerry, Laurent Zelek, Jean-Pierre Lefranc, Rosa Conforti, Jean-Philippe Spano, Alexandra Rousseau and Jacques Bouaud Elicitating Patient Patterns of Physician Non-Compliance with Breast Cancer Guidelines Using Formal Concept Analysis Jacques Bouaud, Nizar Messai, Cédric Laouénan, France Mentré and Brigitte Séroussi Evidence Based Electronic System to Ensure Quality of Care in Trauma Patients Vasiliki Mpletsa, Ioannis Kaklamanos, Konstantinos Birbas and John Mantas OpenEHR-Based Representation of Guideline Compliance Data Through the Example of Stroke Clinical Practice Guidelines Nadim Anani, Rong Chen, Tiago Prazeres Moreira and Sabine Koch Towards Collaborative Chronic Care Using a Clinical Guideline-Based Decision Support System Haifeng Liu, Jing Mei and Guotong Xie A Standardized Middleware as the Core of a Telemonitoring European Project Fabio Vergari, Roberta Gazzarata, Francesco Morandi, Viola Parodi, Simone Naso, Alessandra Arezza, Tulio Salmon Cinotti and Mauro Giacomini Dicoogle Mobile: A Medical Imaging Platform for Android Carlos Viana-Ferreira, Daniel Ferreira, Frederico Valente, Eriksson Monteiro, Carlos Costa and José Luís Oliveira Does Telecare Reduce the Number of Treatment Days? Yuji Akematsu and Masatsugu Tsuji Establishing End-to-End Security in a Nationwide Network for Telecooperation Martin Staemmler, Michael Walz, Gerald Weisser, Uwe Engelmann, Robert Weininger, Antonio Ernstberger and Johannes Sturm

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Quality Through and for Research A Loosely Coupled Framework for Terminology Controlled Distributed EHR Search for Patient Cohort Identification in Clinical Research Lei Zhao, Sarah N. Lim Choi Keung, Adel Taweel, Edward Tyler, Ire Ogunsina, James Rossiter, Brendan C. Delaney, Kevin A. Peterson, F.D. Richard Hobbs and Theodoros N. Arvanitis Key-Linked On-Line Databases for Clinical Research Thomas H. Müller Standardised Representation of Healthcare Information in Secondary Care Research: A Central England Case Study Sarah N. Lim Choi Keung, Ire Ogunsina, James Rossiter, Gavin Langford, Edward Tyler and Theodoros N. Arvanitis

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The Electronic Healthcare Record for Clinical Research (EHR4CR) Information Model and Terminology David Ouagne, Sajjad Hussain, Eric Sadou, Marie-Christine Jaulent and Christel Daniel A DICOM Architecture for Clinicians and Researchers Michael Onken Ophiucus: RDF-Based Visualization Tool for Health Simulation Models Andrew Sutcliffe, Anya Okhmatovskaia, Arash Shaban-Nejad and David Buckeridge Validation and Discovery of Genotype-Phenotype Associations in Chronic Diseases Using Linked Data Jyotishman Pathak, Richard Kiefer, Robert Freimuth and Christopher Chute A Web-Based Tool for Patients Cohorts and Clinical Trials Management P. Fraccaro and Mauro Giacomini Designing and Implementing a Biobanking IT Framework for Multiple Research Scenarios Hans-Ulrich Prokosch, Sebastian Mate, Jan Christoph, Andreas Beck, Felix Köpcke, Stefanie Stephan, Matthias W. Beckmann, Tilman Rau, Arndt Hartmann, Bernd Wullich, Bernhard Breil, Kai-Uwe Eckardt, Stephanie Titze, Jens K. Habermann, Josef Ingenerf, Michael Hackmann, Markus Ries, Thomas Bürkle and Thomas Ganslandt Interoperability in Clinical Research: From Metadata Registries to Semantically Annotated CDISC ODM Philipp Bruland, Bernhard Breil, Fleur Fritz and Martin Dugas Requirements for Semantic Biobanks André Q. Andrade, Markus Kreuzthaler, Janna Hastings, Maria Krestyaninova and Stefan Schulz A Semantic Model for Multimodal Data Mining in Healthcare Information Systems Dimitris Iakovidis and Christos Smailis Assessing the Clinical Uses of Fuzzy Detection Results in the Automated Detection of CVC-Related Infections: A Preliminary Report Jeroen S. de Bruin, Alexander Blacky and Klaus-Peter Adlassnig Assessing the Feasibility of Data Mining Techniques for Early Liver Cancer Detection Mu-Hsing Kuo, Chang-Mao Hung, Jeff Barnett and Fabiola Pinheiro Automatic Extracting of Patient-Related Attributes: Disease, Age, Gender and Race Huijia Zhu, Yuan Ni, Peng Cai, Zhaoming Qiu and Feng Cao Estimating Rheumatoid Arthritis Activity with Infrared Image Analysis Monique Frize and Abiola Ogungbemile Fine-Grained Clinical Outcome Extraction and Polarity Classification Peng Cai, Yuan Ni, Huijia Zhu and Feng Cao Evicase: An Evidence-Based Case Structuring Approach for Personalized Healthcare Boaz Carmeli, Paolo Casali, Anna Goldbraich, Abigail Goldsteen, Carmel Kent, Lisa Licitra, Paolo Locatelli, Nicola Restifo, Ruty Rinott, Elena Sini, Michele Torresani and Zeev Waks

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Reusable Data in Public Health Databases – Problems Encountered in Danish Children’s Database Anna Marie Høstgaard and Louise Pape-Haugaard Secondary Use of Clinical Data in Healthcare Providers – An Overview on Research, Regulatory and Ethical Requirements Matthias Wiesenauer, Christian Johner and Rainer Röhrig Standardizing Intensive Care Device Data to Enable Secondary Usages Josef Ingenerf, Ann-Kristin Kock, Marcel Poelker, Konrad Seidl, Georg Zeplin, Stefan Mersmann and Heinz Handels Why Is Clinical Information Not Reused? Gert Galster

609

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Supporting Decisions Archetype Based Search in an IHE XDS Environment Christoph Rinner, Michael Kohler, Gudrun Hübner-Bloder, Samrend Saboor, Elske Ammenwerth and Georg Duftschmid Concepts for a Personal Health Record Cândido Santos, Tiago Pedrosa, Carlos Costa and José Luis Oliveira Enhancing the Many-to-Many Relations Across IHE Document Sharing Communities Luís S. Ribeiro, Carlos Costa and José Luís Oliveira Standardized EHR Interoperability – Preliminary Results of a German Pilot Project Using the Archetype Methodology Hasan Veseli, Georgy Kopanitsa and Hans Demski The FBE Development Project: Toward Flexible Electronic Standards-Based Biopsycho-Social Individual Records Lucilla Frattura, Andrea Simoncello, Giovanni Bassi, Andrea Soranzio, Stefano Terreni and Fulvio Sbroiavacca An EMR Based Cancer Diary – Utilisation and Initial Usability Evaluation of a New Cancer Data Visualization Tool Markus Ries, Henriette Golcher, Hans-Ulrich Prokosch, Matthias W. Beckmann and Thomas Bürkle Automatic Detection of Inconsistencies Between Free Text and Coded Data in Sarcoma Discharge Letters Ruty Rinott, Michele Torresani, Rossella Bertulli, Abigail Goldsteen, Paolo Casali, Boaz Carmeli and Noam Slonim Fragmentation of Diabetes Treatment in Austria – An Indicator for the Need for Shared Electronic Health Record Systems Georg Duftschmid, Wolfgang Dorda, Gottfried Endel, Karl Fröschl, Walter Gall, Wilfried Grossmann and Milan Hronsky Health Data Collecting and Sharing: Case Studies of Czech e-Health Applications Jana Zvárová, Lenka Lhotská, Libor Seidl and Karel Zvára Ontology-Based Reusable Clinical Document Template Production System Sejin Nam, Sungin Lee, James G. Boram Kim and Hong-Gee Kim The Distributed Use of Electronic Emergency-Department Whiteboards Morten Hertzum

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672 677 683

xxii

A Data-Driven Living Review for Pharmacogenomic Decision Support in Cancer Treatment Gökhan Karakülah, Aslı Suner, Klaus-Peter Adlassnig and Matthias Samwald Electronic Medication Ordering with Integrated Drug Database and Clinical Decision Support System Andreja Čufar, Anže Droljc and Andrej Orel Isolation of Patients with Vancomycin Resistant Enterococci (VRE): Efficacy of an Electronic Alert System Damian Borbolla, Vanina Taliercio, Bibiana Schachner, Ana Maria Gomez Saldano, Estela Salazar, Daniel Luna and Fernan Gonzalez Bernaldo De Quiros Knowledge-Analytics Synergy in Clinical Decision Support Noam Slonim, Boaz Carmeli, Abigail Goldsteen, Oliver Keller, Carmel Kent and Ruty Rinott

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Quality of Data and Patients’ Safety Indicators of Data Quality: Revision of a Guideline for Networked Medical Research Jürgen Stausberg, Ron Pritzkuleit, Carsten O. Schmidt, Thomas Schrader and Michael Nonnemacher Relevance of Drug-Drug Interaction in the ICU – Perceptions of Intensivists and Pharmacists Marjan Askari, Saied Eslami, Mathijs Louws, Dave Dongelmans, Peter Wierenga, Rob Kuiper and Ameen Abu-Hanna Organizing Data Quality Assessment of Shifting Biomedical Data Carlos Sáez, Juan Martínez-Miranda, Montserrat Robles and Juan Miguel García-Gómez Quality Assessment of Automatically Extracted Data from GPs’ EPR Etienne De Clercq, Sarah Moreels, Viviane Van Casteren, Nathalie Bossuyt, Geert Goderis and Stefaan Bartholomeeusen Safety of a Web-Based Insulin Titration System for Patients with Type 2 Diabetes Mellitus – Pilot Study A.C.R. Simon, F. Holleman, W.T. Gude, J.B.L. Hoekstra and N. Peek The Role of Electronic Checklists – Case Study on MRI-Safety Andreas Landmark, May-Britt Selnes, Elisabeth Larsen, Astrid Svensli, Linda Solum and Berit Brattheim EHR and Data Protection Issues in Italy Maria Gabriella Virone Ontology Based Log Content Extraction Engine for a Posteriori Security Control Hanieh Azkia, Nora Cuppens-Boulahia, Frédéric Cuppens and Gouenou Coatrieux Recognition and Privacy Preservation of Paper-Based Health Records Stefan Fenz, Johannes Heurix and Thomas Neubauer Towards Human-Centric Visual Access Control for Clinical Data Management Sascha Fahl, Marian Harbach and Matthew Smith

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Watermarking as a Traceability Standard Gouenou Coatrieux, Catherine Quantin and François-André Allaert A Statistics-Based Approach of Contextualization for Adverse Drug Events Detection and Prevention Emmanuel Chazard, Stéphanie Bernonville, Grégoire Ficheur and Régis Beuscart Identifying Types and Causes of Errors in Mortality Data in a Clinical Registry Using Multiple Information Systems Antonie Koetsier, Niels Peek and Nicolette de Keizer Implementation of Computerized Physician Order Entry (CPOE) with Clinical Decision Support (CDS) Features in Riyadh Hospitals to Improve Quality of Information Mariam S. Almutairi, Rana M. Alseghayyir, Anwar A. Al-Alshikh, Hayat M. Arafah and Mowafa S. Househ Information-Based Sequential Selection of Clinical Tests in Risk Assessment Naama Parush, Tal El-Hay, Michal Ozery-Flato, Ligita Ryliskyte, Zydrune Visockiene and Aleksandras Laucevicius Using EHR Data for Monitoring and Promoting Patient Safety: Reviewing the Evidence on Trigger Tools Persephone Doupi

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Added Value of Web-Based Services Architectural Approach for Quality and Safety Aware HealthCare Social Networks Diego M. López, Bernd Blobel and Carolina González Human Rights Monitoring in Virtual Community Christo El Morr Impact of the Social Networking Applications for Health Information Management for Patients and Physicians Tony Sahama, Jian Liang and Renato Iannella Mobile Social Networking Health (MSNet-Health): Beyond the mHealth Frontier Mowafa Househ On the Support of Flexible Patient Privacy Policies in Social-Medical Discovery Haggai Roitman, Sivan Yogev, Yevgenia Tsimerman and Yardena Peres Technical Requirements of a Social Networking Platform for Senior Citizens Hans Demski, Claudia Hildebrand, José López Bolós, Winfried Tiedge, Stefanie Wengel, Daire Ó. Broin and Ross Palmer A Real-Time Disease Surveillance Architecture Using Social Networks Mustafa Sofean and Matthew Smith Experiences in the Creation of an Electromyography Database to Help Hand Amputated Persons Manfredo Atzori, Arjan Gijsberts, Simone Heynen, Anne-Gabrielle Mittaz Hager, Claudio Castellimi, Barbara Caputo and Henning Müller Exploring the Community Structure of a Diabetes Forum André Dias, Taridzo Chomutare and Taxiarchis Botsis

793 798

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Leveraging Social Media for Preventive Care – A Gamification System and Insights Raymund J. Lin and Xinxin Zhu Online Health Information Search: What Struggles and Empowers the Users? Results of an Online Survey Natalia Pletneva, Alejandro Vargas, Konstantina Kalogianni and Célia Boyer Finding Online Health-Related Information: Usability Issues of Health Portals Nergis A. Gurel Koybasi and Kursat Cagiltay How Medical Doctors and Students Should Use Social Media: A Review of the Main Guidelines for Proposing Practical Recommendations Miguel Angel Mayer, Angela Leis, Alex Mayer and Alejandro Rodriguez-Gonzalez Tracking Changes in Search Behaviour at a Health Web Site Ann-Marie Eklund Trustworthiness and Relevance in Web-Based Clinical Question Answering Sarah Cruchet, Célia Boyer and Lonneke van der Plas

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Learn from Experiences and Critical Thinking A Culture and Power Perspective on the Management of Health Information Technology in Hospitals Lone Stub Petersen and Pernille Bertelsen Economic Impact of a Nationwide Interoperable e-Health System Using the PENG Evaluation Tool L. Parv, J. Saluse, A. Aaviksoo, M. Tiik, R. Sepper and P. Ross How Should We Define eHealth, and Does the Definition Matter? Chris Showell and Christian Nøhr Medical Device Software: A New Challenge Daniela Luzi and Fabrizio Pecoraro The Intellectual Property Management for Data Sharing in a German Liver Cancer Research Network Shan He, Matthias Ganzinger and Petra Knaup The Nature of Unintended Benefits in Health Information Systems Craig E. Kuziemsky, Elizabeth Borycki, Christian Nøhr and Elizabeth Cummings Envisioning Electronic Health Record Systems as Change Management: The Experience of an English Hospital Joining the National Programme for Information Technology Amirhossein Takian Method for Modeling Social Care Processes for National Information Exchange Aki Miettinen, Juha Mykkänen and Maarit Laaksonen On the Attitudes of GPs Toward Novel Features of Their Next EPRs Federico Cabitza Proposal of an Architecture for the National Integration of Electronic Health Records: A Semi-Centralized Approach Asma Al Jarullah and Samir El-Masri

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Uniforming Information Management in Finnish Social Welfare Maarit Laaksonen, Jarmo Kärki and Erja Ailio

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Quality Through Education Assessment in Health Care Education – Modelling and Implementation of a Computer Supported Scoring Process Jayne Alfredsson, Patrick Plichart and Nabil Zary eHealth Education of Professionals in the Baltic Sea Area Ann Bygholm, Julia Günther, Pernille Bertelsen and Christian Nøhr Is It Worth Investing in Online Continuous Education for Healthcare Staff? M. Cristina Mazzoleni, Chiara Maugeri, Carla Rognoni, Alessio Cantoni and Marcello Imbriani Nursing Informatics Competences Still Challenging Nurse Educators Elina Rajalahti and Kaija Saranto Teaching Medicine with a Terminology/Ontology Portal Julien Grosjean, Tayeb Merabti, Nicolas Griffon, Badisse Dahamna and Stéfan J. Darmoni Criteria to Assess the Quality of Virtual Patients Inga Hege, Nabil Zary and Andrzej A. Kononowicz New Approaches to Linking Clinical Guidelines to Virtual Patients Andrzej A. Kononowicz, Inga Hege, Paweł Krawczyk and Nabil Zary Recommendation of Standardized Health Learning Contents Using Archetypes and Semantic Web Technologies María del Carmen Legaz-García, Catalina Martínez-Costa, Marcos Menárguez-Tortosa and Jesualdo Tomás Fernández-Breis SIScaR-GPU: Fast Simulation and Visualization of Intraoperative Scattered Radiation to Support Radiation Protection Training Markus Wagner, Klaus Dresing, Wolfram Ludwig, Christoph Alexander Ahrens and Oliver J. Bott Towards a mLearning Training Solution to the Adoption of a CPOE System Despoina Pakonstantinou, Mikaela Poulymenopoulou, Flora Malamateniou and George Vassilacopoulos Virtual Patient Simulation: A Comparison of Two Approaches for Capacity Building in Sub-Saharan Africa Georges Bediang, Marc-André Raetzo and Antoine Geissbuhler

929 934 939

944 949

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Quality Through Support An Integration of Emergency Department Information and Ambulance Systems Nada Al-Harbi, Samir El-Masri and Basema Saddik Analyzing Primary Care Data to Characterize Inappropriate Emergency Room Use Justin St-Maurice and M.H. Kuo COCPIT: A Tool for Integrated Care Pathway Variance Analysis John Ainsworth and Iain Buchan

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Flexible Medical Image Management Using Service-Oriented Architecture Oded Shaham, Alex Melament, Yuval Barak-Corren, Igor Kostirev, Noam Shmueli and Yardena Peres Measuring Health Care Process Quality with Software Quality Measures Özkan Yildiz and Onur Demirörs Bringing Research to the Point of Care: Hypergenes Project Study Edward Vitkin, Hani Neuvirth-Telem, Boaz Carmeli, Amnon Shabo and Ariel Farkash Do Worklists Work? A Quantitative Approach to the Assessment of an Electronic Patient Record Function Petter Hurlen Log Analysis to Understand Medical Professionals’ Image Searching Behaviour Theodora Tsikrika, Henning Müller and Charles E. Kahn Jr. Ontology-Supported Clinical Profiling for the Evaluation of Obesity and Related Comorbidities Paolo L. Scala, Davide Di Pasquale, Daniele Tresoldi, Claudio L. Lafortuna, Giovanna Rizzo and Marco Padula Texture Analysis Software: Integration with a Radiological Workstation Régis Duvauferrier, Joan Bezy, Valérie Bertaud, Grégoire Toussaint, John Morelli and Jeremy Lasbleiz A Smartphone Application for Preventing Exercise-Induced Glycemic Imbalances in Type 1 Diabetic Patients Omar Vuattolo, Maria Pia Francescato, Vincenzo Della Mea and Agostino Accardo An Android-Enabled Mobile Framework for Ensuring Quality of Life Through Patient-Centric Care Vassiliki Koufi, Flora Malamateniou and George Vassilacopoulos Model Driven Mobile Care for Patients with Type 1 Diabetes Stein Olav Skrøvseth, Eirik Årsand, Fred Godtliebsen and Ragnar M. Joakimsen Personalized Adherence Activity Recognition via Model-Driven Sensor Data Assessment Mark Hsiao, Pei-Yun Hsueh and Sreeram Ramakrishnan Achieving IT-Supported Standardized Nursing Documentation Through Participatory Design Stine Loft Rasmussen, Karen Marie Lyng and Sanne Jensen Consistency of Nurses’ Daily Predictions of Survival in the Intensive Care Lilian Minne, Dave A. Dongelmans, E. de Jonge and Ameen Abuhanna Development of Pain Flowsheet Based on Electronic Nursing Record System JungMin Lee, YoungAh Kim, Hyunsoon Jung and Malsoon Song Electronic Nursing Documentation in a Paediatrics Hospital: Impact on Quality of Care by Using OpenEHR, IHE and HL7 Majda Oštir, Marinka Purkart, Anita Štih, Biljana Prinčič and Andrej Orel ICNP Catalogues for Supporting Nursing Content in Electronic Health Records Amy Coenen, Tae Youn Kim, Claudia C. Bartz, Kay Jansen and Nicholas Hardiker

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INCA – Individual Nomad Clinical Assistant – Supporting Nurses with Mobile Devices Frederic Ehrler, Magali Walesa, Evelyne Sarrey, Rolf Wipfli and Christian Lovis

1079

Posters A System-Theoretical, Architecture-Based Approach to Ontology Management Bernd Blobel, Mathias Brochhausen, Carolina González, Diego M. Lopez and Frank Oemig Characteristics of Health Interventions: A Systematic Analysis of the Austrian Procedure Catalogue Sabrina B. Neururer and Karl-Peter Pfeiffer Describing the Sublanguage of Wound Care in an Adult ICU Riitta Danielsson-Ojala, Heljä Lundgren-Laine and Sanna Salanterä Developing a Patient Education Method – The e-Knowledge Test with Feedback Mervi Siekkinen and Helena Leino-Kilpi Representing Clinical Communication Knowledge Through Database Management System Integration Saif Khairat, Catherine Craven and Yang Gong Semantic Enrichment of Medical Forms – Semi-Autding of ODM-Elements via Web Services Bernhard Breil, Andreas Watermann, Peter Haas, Philipp Dziuballe and Martin Dugas Conducting Requirements Analyses for Research Using Routinely Collected Health Data: A Model Driven Approach Simon de Lusignan, Josephine Cashman, Norman Poh, Georgios Michalakidis, Aaron Mason, Terry Desombre and Paul Krause Classification of Ischaemic Episodes with ST/HR Diagrams Jana Faganeli Pucer, Janez Demšar and Matjaž Kukar Collaborative Development of Knowledge-Based Support Systems: A Case Study Helena Lindgren, Patrik J. Winnberg and Chunli Yan Integration of Data Analysis Methods in Syndromic Surveillance Systems Dimitrios Zikos and Marianna Diomidous Statistical Disclosure Limitation of Health Data Based on Pk-Anonymity Eizen Kimura, Koji Chida, Dai Ikarashi, Koki Hamada and Ken Ishihara Ultradian Rhythms During Day and Night in Normal and COPD Subjects Agostino Accardo, Monica Cusenza, Alberto De Felice, Elisa Fornasa and Giovanni D’Addio A Literature Overview and Comparison of Driving Impairing Condition Assessment Approaches by Health Enabling Technologies Nina Reichwaldt, Susanne Maslak, Klaus-Hendrik Wolf and Reinhold Haux CARDIO-i2b2: Integrating Arrhythmogenic Disease Data in i2b2 Daniele Segagni, Valentina Tibollo, Arianna Dagliati, Carlo Napolitano, Silvia G. Priori and Riccardo Bellazzi

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Impact of Computerized Order Sets on Practitioner Performance Leila Ahmadian and Reza Khajouei IT as an Enabler of Sustainable Use of Data from Innovative Technical Components for Assisted Living Petra Knaup and Lothar Schöpe IT Behind a Platform for Translational Cancer Research – Concept and Objectives Michael Steffens, Gabriele Husmann, Mithat Koca, Martin Lablans, Martina Komor, Sylke Zeissig, Katharina Emrich, Christian Brandts, Hubert Serve, Maria Blettner and Frank Ückert Psychological Evaluation of 24-Hour Home Nursing Care: Application of an Analytic Hierarchy Process to Improve Quality of Life Takeo Shibata, Yoko Shimizu and Hiroko Wada A Clinical Research Analytics Toolkit for Cohort Study Yiqin Yu, Yu Zhu, Xingzhi Sun, Ying Tao, Shuo Zhang, Linhao Xu and Yue Pan An Encapsulated R Application for the Guided Analysis of Genomic Data Matthias Ganzinger, Miriam Kesselmeier, Jasmin Fabian and Petra Knaup First Experiences in Implementing a Software-Based Support for Patient Recruitment at Heidelberg University Hospital Björn Schreiweis, Günter Grüber and Björn Bergh Medical Students and e-Health Mira Hercigonja-Szekeres, Vesna Ilakovac and Krešimir Šolić Multiple Disciplines Synergy Tools for Ph.D. Students of Biomedical Informatics at Charles University in Prague Jana Zvarova, Stepan Svacina, Tatjana Dostalova, Michaela Seydlova and Karel Zvara Translational Meta-Analysis Tool for Temporal Gene Expression Profiles Guenter Tusch and Olvi Tole Pluripotent Stem Cells in Mice Rainer Schmidt, Lena Scheubert, Mitja Lustrek, Dirk Repsilber and Georg Fuellen Introducing a Composite Index of Information Quality for Medical Web Sites Federico Cabitza Concise Healthcare-Associated Infection Reporting and Benchmarking with Minimal Staff Resources Walter Koller, Jeroen de Bruin, Alexander Blacky, Harald Mandl and Klaus-Peter Adlassnig Developing an eLearning Tool Formalizing in YAWL the Guidelines Used in a Transfusion Medicine Service Paola Russo, Miriam Piazza, Giorgio Leonardi, Layla Roncoroni, Carlo Russo, Salvatore Spadaro and Silvana Quaglini e-Learning for Neurological Bladder Management Carla Rognoni, Gabriella Fizzotti, Caterina Pistarini and M. Cristina Mazzoleni Patient Empowerment in the Process of Sickness Certificates Gunnar O. Klein and Kjell Andersson

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Patient Satisfaction in a Context-Aware Hospital Guidance System Eunhye Kim, Sooyoung Yoo, Hwang Hee, Hyunchul Park, Gunhee Kim and Sungdo Ha A Special Query Tool in the Hospital Information System to Recognize Patients and to Increase Patient Numbers for Clinical Trials Mithat Koca, Gabriele Husmann, Jürgen Jesgarz, Martin Overath, Christian Brandts and Hubert Serve Design of a Computerized Provider Order Entry System for Ordering of Chemotherapy SunHee Lee, KiHyuk Lee, Eun-Young Cho, Hee Hwang, KiDong Kim, Young-Jae Cho, JungEun Kim, Jae Hyuk Lee, Rong Min Baek and YoungSik Jeon Development and Evaluation of an Expert System for the Diagnosis of Child Autism Pashalina Lialiou, Dimitrios Zikos and John Mantas ICF Machine: A Web-Based System for Collection of ICF Data Vincenzo Della Mea and Valerio Fioresi ‘Onco Alerts’ to Support Acute Oncology Services Thomas Poulter and Peter A. Bath Promoting Generic Medication Prescribing by Order Interface Redesign: Small Change, Large Impact Sameer Malhotra, Jessica S. Ancker, J. Travis Gossey, Curtis L. Cole, Rainu Kaushal and Adam D. Cheriff Study of Iranian Breast Cancer Registration via Established Online System During 2011 Mohammad Zare, Abolfazl Rezaee, Sholeh Zakiani and Amir Zare Clinical Decision Support for Monitoring Drug-Drug-Interactions and Potassium-Increasing Drug Combinations: Need for Specific Alerts Emmanuel Eschmann, Patrick E. Beeler, Vladimir Kaplan, Markus Schneemann, Gregor Zünd and Jürg Blaser Decision Support System Based Semantic Web for Personalized Patient Care Nassim Douali, Jos De Roo and Marie-Christine Jaulent Development of an Electronic Nursing Records System Based on Information Models and Clinical Practice Guidelines Hyeoun-Ae Park, Yul Ha Min, Eunjoo Jeon, Younglan Kim and Hyun-Young Km Formative Usability Evaluation of a Web-Based Insulin Self-Titration System: Preliminary Results Wouter T. Gude, Airin C.R. Simon, Linda W.P. Peute, Frits Holleman, Joost B.L. Hoekstra, Niels Peek and Monique W.M. Jaspers MInD: Moving in the Dark A. Pepino, G. Sicignano, M. Rovani and G. D’Addio An Example of a Multi-Professional Process-Oriented Structured Documentation Bound to SNOMED CT Carina Zetterberg, Karin Ahlzén, Erika Ericsson and Bengt Kron Clinicians’ Experiences with Videoconferencing in Psychiatry Rolf Wynn, Svein Bergvik, Gunn Pettersen and Sturla Fossum

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Development and Management of Public Health Education System Against Emerging Infectious Diseases Myungja Koh, Parvati Dev, Eun-Jung Lee, Byung-Ki Koo, Kyung-Oak Lee, Kukhwa Ha, Heesun Yang, Gilwon Kang and Youngsung Lee Pharmaceutical Validation of Medication Orders Using an OWL Ontology and Business Rules Amina Chniti, Abdelali Boussadi, Patrice Degoulet, Patrick Albert and Jean Charlet A Way to Motivate Danish GPs to Implement a New National Service Alice Kristensen and Bente Wengler Trend Analysis and Future Development of Taiwan Electronic Medical Records Wan-Chi Ke, Yi-Chung Hsieh, Yen-Chen Chen, En-Te Lin and Hung-Wen Chiu Subject Index Author Index

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