Promote Positive Patient Outcomes.
Helping you Meet the National Standards and Guidelines Healthcare associated infections such as bloodstream or surgical site infections can result from organisms topical antiseptics is therefore a critical infection prevention measure that should be performed prior to invasive procedures that puncture the skin. Antiseptic solutions containing chlorhexidine gluconate have 1,2,3 been found superior to povidone iodine in preventing surgical site infections. Chlorhexidine has a broad spectrum of activity, particularly against gram-negative bacteria.
4
One of the
market. 5
Liquid Soap Povidone Iodine Aqueous Solution 10% Chlorhexidine Gluconate 4% Iso-propanol 70% Isopropyl Alcohol 70% and Chlorhexidine 0.5%
REDUCTION OF SKIN BACTERIA
6 %
log 10
0.0
0.0
90.01
.0
90.02
.0
99.93
.0 0 minutes
60 minutes
180 minutes
TIME AFTER DISINFECTION
National Standards and Guidelines in Perioperative Nursing The perioperative skin antimicrobial agent used should; t$Pntain broad spectrum properties t#FOPOJSSJUating and non-toxic t#FSBQJEBDUJOH
7,8,9
Surgical Skin Prep Reference Guide Activity and Considerations for Preoperative Skin Preparation Antiseptics Persistent/ residual activity
Antiseptic Agent
Use on eye or ear
Use on mucous membranes
None
No. Can cause corneal damage or nerve damage.
No
Excellent
No. Can cause corneal damage. Can cause deafness if in contact with inner ear.
Minimal
Yes. Moderate ocular irritant.
Excellent
No. Can cause corneal damage. Can cause deafness if in contact with inner ear.
Moderate
No. Can cause corneal damage or nerve damage.
Alcohol
Chlorhexidine Gluconate
Povidone-Iodine
Chlorhexidine Gluconate with Alcohol
Iodophor with Alcohol
Parachoroxylenol
Moderate
Surgical Specialty Cosmetic - Face Ophthalmology - Eye Ear Dental Cosmetic - No Face Neck - Thyroid Neck - Central Line Neurosurgical - Head (avoid contact with eyes, ears and mouth) Neurosurgical - Thoracic Spine (avoid contact with meninges) Orthopaedic - Shoulder Orthopaedic - Hip
Yes
Use with caution
Yes
No
No
Yes
2% CHG with 70% IPA
O O O O P P P P P P P
Please refer to product package for complete instructions for use.
Contraindications
5
Cautions Flammable. Does not penetrate organic material. Optimum concentration is 60% to 90%.
Known hypersensitivity to drug or any ingredient. Lumbar puncture and use on meninges.
Prolonged skin contact may cause irritation in sensitive individuals. Rare severe hypersensitivity reactions have been reported. Use with caution on mucous membranes.
Sensitivity to povidone-
Prolonged skin hypersensitivity may cause irritation. May cause iodism in susceptible individuals, avoid use in neonates. Inactivated by blood.
allergies are not a contraindication). Known hypersensitivity to drug or any ingredient. Lumbar puncture and use on meninges. Sensitivity to povidone-iodine. are not a contraindication.)
Known hypersensitivity to PCMX or any ingredient.
Surgical Specialty Orthopaedic - Knee Orthopaedic - Ankle Orthopaedic - Foot Orthopaedic - Scopes - Irrigation Orthopaedic - Hand - Upper Limb Urology/Gyne/Mucous Membranes C-Sections Open Wound Cardiac - Vascular Chest/Abdomen
P Recommended
Flammable
Flammable
presence of organic matter. The
The FDA continues to evaluate PCMX.
2% CHG with 70% IPA
P P P P P O P O P P O Not recommended
3M ™ SoluPrep
™
Antiseptic Solutions
For Hospital and Healthcare Professional Use Antiseptic for preparation of the patient’s skin prior to invasive procedure on dry skin sites only. Helps reduce bacteria
SoluPrep
™
Antiseptic Applicator
Single unit dose package. Active ingredients are pre-mixed. Eliminates risk of possible contamination associated with open bottles. Maximum treatment area 52cm x 52cm.
SoluPrep
™
Antiseptic Sponges
Single unit dose packages containing 2 or 4 sponges. Sponges impregnated with antiseptic solution. Eliminates risk of possible contamination associated with opened bottles of antiseptic solution. Convenient dispenser pack system. Maximum treatment area for one sponge is 40cm x 40cm.
SoluPrep
™
Antiseptic Solution
Single unit dose. Maximum treatment area for 100mL covers 88cm x 87cm.
Application Technique
10
The following diagram demonstrates the method of application that was used in the testing of SoluPrep ™ products. 11 Allow the product to completely air dry before draping the patient (3 minutes for dry skin). This provides time for optimal 7,8,12
Please refer to product package for complete instructions for use.
15 Seconds 15 Seconds
Apply the antiseptic in a back-and-forth motion in several directions with gentle friction. This action promotes binding of
Product Code
Each/ Box
Box/ Case
25
2
100.25
SoluPrep™ Antiseptic Sponge Large 2% w/v chlorhexidine gluconate and 70% v/v isopropyl alcohol tray containing 4 sponges and 97mL tinted solution ARTG No 226782
30
2
100.27
SoluPrep™ Antiseptic Sponge Small 2% w/v chlorhexidine gluconate and 70% v/v isopropyl alcohol tray containing 2 sponges and 50mL tinted solution ARTG No 226782
30
2
103.26
SoluPrep™ Antiseptic Solution 2% w/v chlorhexidine gluconate and 70% v/v isopropyl alcohol contains 225mL tinted solution ARTG No 226785
48
1
100.24
Product Description
2% w/v chlorhexidine gluconate and 70% v/v isopropyl alcohol contains 35mL of tinted solution ARTG No 226780
For clinical and sales information, contact your 3M Account Representative or 3M Customer Service on: Australia 1300 363 878 or New Zealand 0800 80 81 82
References 1. Darousiche RO, Wall MJ, Jr., Itani KM, Otterson MF, Webb AL, Carrick MM et al. ‘Chlorhexidine-alcohol versus povidone-iodine for surgical site antisepsis.’ New England Journal of Medicine 2010; 362(1):18-26. 2. Lee,I., Agarwal, R., Lee, B., Fishman. N., Umscheid, C., ‘Systematic Review and Cost Analysis Comparing Use of Chlorhexidine with Use of Iodine for Preoperative Skin Antisepsis to Prevent Surgical Site Infection.’ Infection Control and Hospital Epidemiology, 2010; 31(12):1219-1229. 3. Noorani, I., Rabey, N., Walsh, S.R., Davies, R.J., ‘Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in cleancontaminated surgery.’ British Journal of Surgery 2010; 97:1614-1620. 4. Denton. G. W., ‘Chlorhexidine’. In Seymour S. Block (Ed.) Disinfection, Sterilisation, and Preservation. 4th Ed., Lea & Febiger, Williams & Wilkins, Media PA, 1991:279. 5. Larson. E, APIC guidelines for infection control practice: guideline for use of topical antimicrobial agents. Am J Infect Control . 1988; 16(6):253-65. 6. Hospital Epidemiology and Infection Control, 2e, edited by C, Glen Mayhall. Lippincott Williams & Wilkins, Philadelphia, 1999. 7. A.C.O.R.N Standards for Perioperative Nursing. ‘Standard: Skin Preparation of the Patient. 2.1. 2014-2015:237. 8. Standards, Guidelines and Position Statements for Perioperative Registered Nursing Practice A.O.R.N. 2009 9. Lim, K. S., and P. C. A. Kam. ‘Chlorhexidine--pharmacology and clinical applications.’ Anaesthesia and Intensive Care. 2008; (36.4):502-512. 10. Tanner J., “Methods of skin antisepsis for preventing SSIs.” Nursing Times; 108:37, 20-22. 11. 12. Tanner. J., Swarbrook, S., and Stuart, J. “Surgical hand antisepsis to reduce surgical site infection”. Cochrane Database of Systematic Reviews , 2008, Issue 1. Art. No.: CD004288. DOI: 10.1002/14651858.CD004288.pub2
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SIV1024-02/2016
