Professor and Director Heart Disease Prevention Program Division of Cardiology. President, American Society for Preventive Cardiology
Diabetes and Cardiometabolic Syndrome: Epidemiology and Management for Prevention of CVD Nathan D. Wong, PhD, FACC, FAHA N h D W PhD FACC FAHA Profess...
Diabetes and Cardiometabolic Syndrome: Epidemiology and Management for Prevention of CVD Nathan D. Wong, PhD, FACC, FAHA N h D W PhD FACC FAHA Professor and Director H Heart Disease Prevention Program Di P i P Division of Cardiology U i University of California, Irvine i f C lif i I i President, American Society for Preventive C di l Cardiology
Presentation Objectives • Review the epidemiology implicating metabolic syndrome and diabetes in cardiovascular risk • Discuss the clinical trial evidence for the y management, g g glycemic, y role of lifestyle lipid, and blood pressure control. • Address the ABCs of lifestyle y and clinical management of metabolic syndrome and diabetes aimed to reduce cardiovascular di disease risk. i k
Obesity Trends* Among U.S. Adults: BRFSS 2008 BRFSS ‐
No Data
30% %
Abdominal Adiposity Is Associated With Increased Risk of Diabetes With Increased Risk of Diabetes Relative Risk of Diiabetes
25
P value for trend =25 Al-Nozha et al. (Saudi Med J 2004): 26.2% males, 21.5% females (p75% of all hospitalizations for diabetic complications li ti
• 50% of patients with type 2 diabetes have preexisting CAD. (This number may be less now that more younger people are diagnosed with diabetes ) diabetes.)
• 1/3 of patients presenting with myocardial infarction have undiagnosed diabetes mellitus Lewis GF. Can J Cardiol. 1995;11(suppl C):24C-28C Norhammar A, et.al. Lancet 2002;359;2140-2144
Risk of Cardiovascular Events in Patients with Diabetes: Diabetes: Framingham Diabetes: Framingham Study Framingham Study Study _________________________________________________________________
Cardiovascular Event
Age-adjusted Age adjusted Biennial Rate Per 1000 Men Women