Pediatric Surgery: The Newborn. Newborn Physiology. Newborn Physiology

Pediatric Surgery: The Newborn Barry Newman, M.D. and Lorretto Glynn, M.D. Newborn Physiology • Thermoregulation – Increase metabolic activity and he...
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Pediatric Surgery: The Newborn Barry Newman, M.D. and Lorretto Glynn, M.D.

Newborn Physiology • Thermoregulation – Increase metabolic activity and heat production (brown fat) – Heat produced at high cost energy and oxygen – Takes energy/oxygen away from vital organs

Newborn Physiology • • • • •

Smaller more premature then worse heat loss Incubators: “penalty box” Radian warmers Warming blankets “French fry lights”

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Newborn Physiology • Fluid and Electrolyte Management – Neonate’s TBW 80% weight at birth – Extracellular 40% birth weight – Adult TBW (60%) and ECCF volume (20%) reached by 1 year of age – DOL #1: prediuretic (UO 1ml/kg/hr) – DOL #2 and 3: diuretic (UO 7ml/kg/hr) – DOL #4 on: UO and natriuresis depend

Newborn Physiology • • • • •

DOL #1 – 3: 60-80 ml/kg/day DOL #4: 100 ml/kg/day Make changes PRN Replace GI losses (obstruction, NEC) Replace Evaporative losses (gastroschisis)

Newborn Physiology • Metabolism and Nutrition – – – – –

Increased requirements due to rapid growth and development Add illness, temperature regulation Fetus: glucose and easy way Neonate: glycogenolysis, gluconeogenesis, exogenous sources Provide 100-110 kcal/kg/day infants

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Newborn physiology • Respiratory – Growth: starts in utero and continues up to age 8 – Maturation: type II pneumocytes for surfactant production – Fetal circulation: ductus arteriosis and foramen ovale shut blood away from lungs

Newborn Physiology • Transition: closure of DA, FO when drop in pulmonary vascular resistance at birth • Support with mechanical ventilation: pressure vs.. volume cycles • Oscillating ventilator • Nitric oxide • Extracorporal Membrane Oxygenation

Newborn Physiology • PICTURE HERE

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Hernia and Hydorcele • • • •

Testes start intrabdominal and descent 20% patent processus vaginalis Hermla sac anteromedial to cord (retroperitoneal) Open processus can result in hemia (viscera) or communicating hydorcele (peritoneal fluid)

Hernia and Hydorcele • Fluid may get trapped in tunica but PV closed: non-communicating hydorcele • No operation necessary for non-communicating hydrocele • Repair recommended for communicating hydrocele and hernia

Hernia and Hydrocele • • • • • •

Most infant hernias indirect Incidence 0.8-4.4% Male; female + 6-8:1 Premature: up to 70% have hernia 60% incarcerate first 6 mos Inguinal incision, high litigation sac, excision of hydorcele

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Hernial and Hydrocele • • • •

Recurrence