OVERWEIGHT and obesity increase the risk of death in

Journal of Gerontology: MEDICAL SCIENCES Cite journal as: J Gerontol A Biol Sci Med Sci doi:10.1093/gerona/glr147 © The Author 2011. Published by Oxf...
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Journal of Gerontology: MEDICAL SCIENCES Cite journal as: J Gerontol A Biol Sci Med Sci doi:10.1093/gerona/glr147

© The Author 2011. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: [email protected].

Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio as Predictors of Mortality in Nonagenarians: The Vitality 90+ Study Inna Lisko,1,2,3 Kristina Tiainen,1 Sari Stenholm,4 Tiina Luukkaala,1,2 Antti Hervonen,1 and Marja Jylhä1 1School

of Health Sciences, University of Tampere, Finland. Center of Pirkanmaa Hospital District, Tampere, Finland. 3Gerontology Research Centre, Department of Health Sciences, University of Jyväskylä, Finland. 4Department of Health, Functional Capacity and Welfare, National Institute for Health and Welfare, Turku, Finland. 2Science

Address correspondence to Inna Lisko, MSc, Department of Health Sciences (VIV), University of Jyväskylä, P.O. Box 35, Jyväskylä, FIN-40014, Finland. Email:[email protected]

Background.  The associations of body mass index (BMI) and abdominal obesity with mortality among very old people are poorly known. The purpose of this study was to investigate the association of BMI, waist circumference (WC), and waist-to-hip ratio with mortality in nonagenarians. Methods.  This study is part of a prospective population-based study, Vitality 90+, including both community-dwelling and institutionalized persons from Tampere, Finland. Altogether 192 women and 65 men aged 90 years were subjected to anthropometric measurements, a baseline interview, and a 4-year mortality follow-up. Cox proportional hazards models were used in the statistical analyses. Results.  In men, normal weight indicated a three times higher mortality risk (hazard ratio [HR] 3.09, 95% confidence interval [CI] 1.35–7.06) compared with overweight, and WC was inversely associated with mortality (HR 0.96, 95% CI 0.93–1.00) after adjustment for covariates. In women, the univariate waist-to-hip ratio (HR 1.43, 95% CI 1.06–1.92) and BMI-adjusted waist-to-hip ratio (HR 1.45, 95% CI 1.07–1.97) were positively associated with mortality. Also, overweight women whose WC was

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