The 2016 Joint Conference

on Advances in Pediatric Cardiovascular Disease Management

Sept. 16 – 17, 2016 Disney’s Paradise Pier Hotel 1717 S. Disneyland Drive Anaheim, CA 92802

2016 Joint Conference on Advances in Pediatric Cardiovascular Disease Management The Heart Institute at Children’s Hospital Los Angeles and the Keck School of Medicine of the University of Southern California (USC) are pleased to announce the 2016 Joint Conference on Advances in Pediatric Cardiovascular Disease Management. The Conference is a joint effort between Children’s Hospital Los Angeles, the University of Michigan Congenital Heart Center and the Children’s Healthcare of Atlanta, and rotates between the institutions each year. This year’s conference will feature national and international speakers discussing challenging heart lesions and other important topics.

Conference Goals The conference will address a variety of knowledge gaps, with the overarching goal of improving the care of the patient with congenital heart disease. Examples of specific topics include new diagnostic and treatment options for patients with complex congenital heart lesions and therapeutic innovations.

Educational Objective Participants will leave knowing the most up-to-date methods of treatment and diagnosis for congenital heart patients and will be able to implement newly gained knowledge in their current practice.

Target Audience The conference is intended for pediatric cardiologists, pediatric cardiothoracic surgeons, nurses, perfusionists and other health care professionals who treat children with complex heart disease.

Accreditation and Designation Accreditation Statement Children’s Hospital Los Angeles is accredited by the Institute for Medical Quality/ California Medical Association (IMQ/CMA) to provide continuing medical education for physicians. Children’s Hospital Los Angeles takes responsibility for the content, quality and scientific integrity of this CME activity. Children’s Hospital Los Angeles designates this the 2016 Joint Conference on Advances in Pediatric Cardiovascular Disease Management for a maximum of 14.25 hours of AMA PRA Category 1 Credit. Physicians should only claim credit commensurate with the extent of their participation in the activity. This credit may also be applied to the CMA Certification in Continuing Medical Education.

Disclosure Statement Children’s Hospital Los Angeles maintains control over the content of this CME activity, and will disclose to the audience any faculty or planner relationship with a pharmaceutical or industrial concern that might pose a potential, apparent or real conflict of interest with regard to its contribution to the program.

Nurses Children’s Hospital Los Angeles is accredited as a provider of continuing education by the California Board of Registered Nursing, Provider Number CEP 183. This presentation is approved for a total of 16 CE contact hours.

Conference Schedule Thursday, Sept. 15, 2016 – Sea Breeze Foyer 5 – 7 p.m.

Registration

Friday, Sept. 16, 2016 – Pacific Ballroom 7 – 7:25 a.m.

Registration/Continental Breakfast

7:25 – 7:30 a.m.

Welcome

Winfield J. Wells, MD

Long-Term Outcomes After SV Palliation Moderators: Richard Jonas, MD, and Michael Silka, MD 7:30 – 7:55 a.m.

Impact of the Source of Pulmonary Blood Flow on



Longer-Term Cardiac Function Post-Norwood

Pierre Wong, MD

Children’s Hospital Los Angeles

7:55 – 8:20 a.m.

Functional Status of Long-Term Survivors of SV Palliation

Stephen Paridon, MD

Children’s Hospital of Philadelphia

8:20 – 8:45 a.m.

Transplant for Failed SV Palliation Patients



Kirk K. Kanter, MD



Children’s Healthcare of Atlanta

8:45 – 9 a.m.

Panel Discussion and Q&A

Conference Schedule (continued) Advances in 3-D Imaging and Modeling Moderators: Emile Bacha, MD, and Jon Detterich, MD 9 – 9:25 a.m.

CT and MRI Modeling of Complex Congenital Heart Defects



Stephen P. Sanders, MD

Boston Children’s Hospital 9:25 – 9:50 a.m.

3-D Printing of Congenital Heart Defects



Laura J. Oliveri, MD



Children’s National Medical Center

9:50 – 10 a.m.

Panel Discussion and Q&A

10 – 10:30 a.m.

Break

Invited Lecture I Introduction: Winfield J. Wells, MD 10:30 – 11:15 a.m.

Leonardo, His Life and Times and the Reproductive System



Mr. Francis C. Wells, MA, MS, BSc



Papworth Hospital, Papworth Everard

Cambridge, UK

The California Congenital Heart Consortium Moderators: Brian Reemtsen, MD, and Anita Moon-Grady, MD 11:15 – 11:40 a.m.

Building a Consortium to Improve Congenital

Heart Disease Outcomes

Ram Kumar Subramanyan, MD, PhD



Children’s Hospital Los Angeles

11:40 a.m. – 12:05 p.m. Initial and Future Studies to be Conducted by the Consortium

Tara Karamlou, MD, MS



University of California, San Francisco

12:05 – 12:20 p.m.

Panel Discussion and Q&A

12:20 – 1 p.m.

Lunch

The Genetics of Congenital Heart Disease Moderators: Tara Karamlou, MD, and Jay Pruetz, MD 1 – 1:25 p.m.

Correlation of Genetic Anomalies With Clinical Outcomes in



Patients With Congenital Heart Disease

Richard Kim, MD

Children’s Hospital Los Angeles

1:25 – 1:50 p.m.

Application of Genetic Findings to the Management of

Congenital Heart Disease Bruce Gelb, MD

Mindich Child Health and Development Institute

1:50 – 2:05 p.m.

Panel Discussion and Q&A

Innovations in the Treatment of Congenital Heart Disease Moderators: Winfield Wells, MD, and John Wood, MD 2:05– 2:30 p.m.

Ambulatory Monitoring of Fontan Pressures Using an

Implantable Wireless Sensor

Martin L. Bocks, MD



University of Michigan Health System

Conference Schedule (continued) 2:30– 2:55 p.m.

MRI Guidelines: Cardiac Intervention

Kanishka Ratnayaka, MD Rady’s Children’s Hospital 2:55– 3:20 p.m.

Bioprinting



Roger R. Markwald, PhD



Medical University of South Carolina

3:20– 3:40 p.m.

Panel Discussion and Q&A

3:40 p.m.

Adjourn

Saturday, Sept. 17, 2016 – Pacific Ballroom 7 – 8 a.m.

Continental Breakfast

Management of Difficult Valve Problems in Congenital Heart Disease Moderators: Jonathan Chen, MD, and Pierre Wong, MD 8 – 8:25 a.m.

Hybrid Mitral Valve Replacement in Infants

Emile Bacha, MD

Morgan Stanley Children’s Hospital – New York-Presbyterian

8:25 – 8:50 a.m.

Non-Marfans Aortic Root Interventions



Vaughn A. Starnes, MD



Children’s Hospital Los Angeles

8:50 – 9:15 a.m.

Advances in Percutaneous Valve Therapy in Children With CHD

Frank Ing, MD

Children’s Hospital Los Angeles

9:15 – 9:30 a.m.

Panel Discussion and Q&A

Mechanical Support in Patients With Congenital Heart Disease Moderators: Kirk Kanter, MD, and Lara Nelson, MD 9:30 – 9:55 a.m.

ECMO: Current Practice and Outcomes



Cynthia S. Herrington, MD



Children’s Hospital Los Angeles

9:55 – 10:20 a.m.

Pediatric VADs



Jonathan M. Chen, MD

Seattle Children’s Hospital 10:20 – 10:45 a.m.

Mechanical Support for SV Patients



Richard A. Jonas, MD



Children’s National Health System

10:45 – 11 a.m.

Panel Discussion and Q&A

Invited Lecture II Introduction: Winfield J. Wells, MD 11 – 11:45 a.m.

The Heart of Leonardo: A Practical Assessment of His



Observations on Detailed Heart Structure and Function



Mr. Francis C. Wells, MA, MS, BSc



Papworth Hospital, Papworth Everard

Cambridge, UK

Conference Schedule (continued) Invited Lecture III Introduction: Frank Ing, MD 11:45 a.m. – 12:15 p.m. Fetal Cardiac Intervention: Past, Present, Future?

Anita J. Moon-Grady, MD, FACC, FASE



University of California, San Francisco

12:15 – 1 p.m.

Lunch

Management of Thrombotic Complications in Children Moderators: Ram Subramanyan, MD, and Sylvia del Castillo, MD 1 – 1:25 p.m.

Advances in the Management and Monitoring of

Anticoagulation in Children Guy Young, MD

Children’s Hospital Los Angeles

1:25 – 1:50 p.m.

Changing the Paradigm in Management of Venous Obstruction

Frank Ing, MD

Children’s Hospital Los Angeles

1:50 – 2 p.m.

Panel Discussion and Q&A

Innovations in the Treatment of Congenital Heart Disease Moderators: Richard Ohye, MD, and Jon Detterich, MD 2 – 2:25 p.m.

Femoral Vein Homografts as Conduits

Richard Jonas, MD

Children’s National Health System

2:25 – 2:50 p.m.

Computer Modeling for Congenital Heart Disease



Kirk K. Kanter, MD



Children’s Healthcare of Atlanta

2:50 – 3:20 p.m.

What Parents Want to Know About Congenital Heart Programs



Amy Baskin, Director of Programs



Pediatric Congenital Heart Association

Jennifer Page

Mother of CHD Patient



Heart Ambassador for Children’s Hospital Los Angeles

3:20 – 4 p.m.

Panel Discussion and Q&A

4 p.m. Adjourn

The Joint Conference on Advances in Pediatric Cardiovascular Disease Management Faculty Emile F. Bacha, MD Calvin F. Barber Professor of Surgery Chief, Division of Cardiac, Thoracic and Vascular Surgery Director, Congenital Pediatric Cardiac Surgery Morgan Stanley Childen’s Hospital – New York-Presbyterian Martin L. Bocks, MD Assistant Professor of Pediatric and Internal Medicine Pediatric Interventional Cardiology Adult Congenital Cardiology University of Michigan Health System Jonathan M. Chen, MD Chief, Congenital Cardiac Surgery Co-Director, Heart Center Seattle Children’s Hospital Professor, Samuel and Althea Stroum Chair in Pediatric Cardiovascular Surgery University of Washington School of Medicine Bruce Gelb, MD Gogel Family Professor and Director, Mindich Child Health Development Institute Professor of Pediatrics and Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai Anita J. Moon-Grady, MD, FACC, FASE Professor of Clinical Pediatrics Director, Fetal Cardiovascular Program University of California, San Francisco Richard A. Jonas, MD Chief, Cardiac Surgery Co-Director, Children’s National Heart Institute Cohen Funger Professor of Surgery Children’s National Health System Kirk K. Kanter, MD Pediatric Cardiac Surgery Professor of Surgery Emory University School of Medicine Children’s Healthcare of Atlanta Tara Karamlou, MD, MS Assistant Professor of Surgery UCSF Benioff Children’s Hospital University of California, San Francisco

Roger R. Markwald, PhD Director, Cardiovascular Developmental Biology Center Distinguished University Professor Medical University of South Carolina Richard G. Ohye, MD Head, Section of Pediatric Cardiovascular Surgery Department of Cardiac Surgery University of Michigan Health System Laura J. Oliveri, MD Assistant Professor of Pediatrics George Washington University, School of Medicine Division of Cardiology Children’s National Health System Stephen M. Paridon, MD Medical Director Cardiovascular Physiology Laboratory Children’s Hospital of Philadelphia Professor of Pediatrics Pearlman’s School of Medicine University of Pennsylvania Kanishka Ratnayaka, MD Interventional Pediatric Cardiology Interventional Cardiac MRI Associate Professor of Pediatrics Rady’s Children’s Hospital Brian L. Reemtsen, MD Assistant Professor, Surgery Chief, Congenital Heart Surgery Mattel’s Children’s Hospital Ronald Reagan – UCLA Medical Center Stephen P. Sanders, MD Professor of Pediatrics (Cardiology), Part-time Harvard Medical School Director, Cardiac Registry Departments of Cardiology, Pathology, and Cardiac Surgery Boston Children’s Hospital Mr. Francis C. Wells, MA, MS, BSc (Horns), FRCS (Eng.), MB, BS Consultant Cardiothoracic Surgeon Papworth Hospital, Papworth Everard Cambridge, UK

Children’s Hospital Los Angeles Faculty Sylvia del Castillo, MD Medical Director, Cardiothoracic Intensive Care Unit Children’s Hospital Los Angeles Assistant Professor of Pediatrics Keck School of Medicine of USC Jon Dettrich, MD Attending Physician, Division of Cardiology Children's Hospital Los Angeles Assistant Professor of Pediatrics Keck School of Medicine of USC Cynthia S. Herrington, MD Program Director, Congenital Cardiac Surgery Fellowship Surgical Director, Heart Transplant Program Children’s Hospital Los Angeles Associate Professor of Surgery Keck School of Medicine of USC Frank Ing, MD Chief, Division of Cardiology Director, Cardiac Catheterization Lab Children’s Hospital Los Angeles Professor of Clinical Pediatrics Keck School of Medicine of USC Richard W. Kim, MD Attending Physician, Division of Cardiothoracic Surgery Children’s Hospital Los Angeles Assistant Professor of Surgery Keck School of Medicine of USC Lara P. Nelson, MD Attending Physician, Department of Anesthesiology Critical Care Medicine Children’s Hospital Los Angeles Assistant Professor of Clinical Pediatrics Keck School of Medicine of USC Jay D. Pruetz, MD Director of Fetal Cardiology Division of Cardiology Children’s Hospital Los Angeles Assistant Professor of Pediatric Cardiology Keck School of Medicine of USC Michael J. Silka, MD Division of Cardiology Children’s Hospital Los Angeles Professor of Clinical Pediatrics Keck School of Medicine of USC

Vaughn A. Starnes, MD Head, Division of Cardiothoracic Surgery Co-Director, Heart Institute Children's Hospital Los Angeles H. Russell Smith Foundation Chair Distinguished Professor and Chairman Department of Surgery Keck School of Medicine of USC Ram Kumar Subramanyan, MD, PhD Attending Physician, Division of Cardiothoracic Surgery Children’s Hospital Los Angeles Assistant Professor of Surgery Keck School of Medicine of USC Winfield J. Wells, MD Attending Physician, Division of Cardiothoracic Surgery Children’s Hospital Los Angeles Associate Professor of Surgery Keck School of Medicine of USC Pierre Wong, MD Director, Echocardiography Children’s Hospital Los Angeles Associate Professor Keck School of Medicine of USC John C. Wood, MD, PhD Director, Cardiovascular MRI Children’s Hospital Los Angeles Associate Professor of Pediatric Cardiology Keck School of Medicine of USC Guy Young, MD Director, Hemostasis and Thrombosis Center Children’s Hospital Los Angeles Professor of Pediatrics (Clinical Scholar) Keck School of Medicine of USC

Other Conference Speakers: Amy Basken Director of Programs Pediatric Congenital Heart Association Jennifer Page Mother of CHD patient Heart Ambassador for Children’s Hospital Los Angeles

Registration Information The 2016 Joint Conference on Advances in Pediatric Cardiovascular Disease Management will take place in the beautiful Pacific Ballroom at the Disney’s Paradise Pier Hotel in Anaheim, California.

Disney’s Paradise Pier Hotel



1717 S. Disneyland Drive



Anaheim, CA 92802

714-999-0990 Online: CHLA.org/HeartConference On-site: On-site registration will take place at the Sea Breeze Foyer, located outside of the Pacific Ballroom on Thursday, Sept. 15, from 5 - 7 p.m., and Friday, Sept. 16, at 7 a.m. Physician registration fee: $400 Nurses and perfusionists registration fee: $200 For additional information, please contact Martha Gomez at [email protected] or 323-361-4941.

Hotel Information A block of rooms has been reserved with a special $229 rate until Aug. 25, 2016. Applicable taxes are not included. Rooms are based on availability. To make your reservations: • Call 714-520-5005 • Identify yourself as attending the “Children’s Hospital Los Angeles September Meeting” • Special Link: https://resweb.passkey.com/go/GPCI16A Please note: Reservation deadline is Aug. 25, 2016. Reservations made after this date will be accepted only if space is available.

The Happiest Place on Earth! To purchase specially priced Disneyland Resort Theme Park tickets, please visit: http://disneytickets.disney.go.com/store/GPCI16A These special ticket prices are not available once you arrive at the resort. The ticket store closes at 9 p.m. PST on Sept. 14, 2016. Don't delay! Prices are subject to change without notice.

Future Meetings: Fall 2017 Children’s Healthcare of Atlanta Fall 2018 University of Michigan Congenital Heart Center

CHLA.org