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North Carolina Ag Biotech: Economic Growth Report January 2015 Compiled by Karin Shank, Library and Information Services Amber Niebauer, Agricultural Biotechnology Initiative ncbiotech.org/agbiotech

Contents Economic Growth Report: Executive Summary ....................................................................................... 1 North Carolina Ag Biotech: Economic Growth Report ........................................................................... 2 Ag Biotech in North Carolina .......................................................................................................................................... 2 Ag Biotech Companies and Employees ................................................................................................................. 2 Prospective Growth in Ag Biotech........................................................................................................................... 4 NCBiotech Support for Ag Biotech ............................................................................................................................... 4 Agricultural Bioscience Company and Entrepreneurial Profile System .................................................. 4 Ag-focused Biotech Awards Bring High Returns to North Carolina .......................................................... 5 Overview of Ag Industry in North Carolina .............................................................................................................. 5 Agriculture/Agribusiness Value-Added Analysis ............................................................................................. 5 Diversity of Agricultural Production ...................................................................................................................... 6 Agricultural Feedstock & Chemicals Sector Analysis ...................................................................................... 7 Ag-related Degrees Awarded..................................................................................................................................... 8 Federal Ag-related Grant Funding for North Carolina .................................................................................... 9 Plant-related Patents Granted in North Carolina ........................................................................................... 10

Appendix 1: Ag Biotech Companies/Sites Founded or Relocated to NC since 2010 ................ 11 Appendix 2: Full Prospective Growth Report ......................................................................................... 12 Prospective Ag Biotech Investments ................................................................................................................... 12 Prospective Ag Biotech Job Announcements ................................................................................................... 13

Appendix 3: North Carolina Agriculture and Agribusiness Income ............................................... 14 Economic Analysis 2009-2014 (data from 2007-2012) ............................................................................. 14

Appendix 4: Battelle Analysis ....................................................................................................................... 15 Battelle's Agricultural Feedstock & Chemicals Sector Analysis’ NAICS Codes .................................. 15 Leading States Bioscience-Related Patents by Class Group, 2009-2013 ............................................. 15

Appendix 5: Patent Classification ................................................................................................................ 16 Plant-related Patent Classification Codes ......................................................................................................... 16

Appendix 6: Schedule for Updates ............................................................................................................... 17 Quarterly Updates ....................................................................................................................................................... 17 Annual Updates ............................................................................................................................................................ 17

Economic Growth Report: Executive Summary The AgBiotech Initiative at NCBiotech was formed in January 2010 to stimulate the growth of agricultural biotechnology in North Carolina to create new opportunities that generate jobs, strengthen the economy and produce the technologies and products that help meet the global demand for food, fuel, medicine and sustainable materials. North Carolina is the global hub of ag biotech with tremendous assets driving the development of new innovations in ag biotech, combining the state’s two largest industries – agriculture and biotechnology. Ag biotech applies the tools of biotech to crops, livestock, forestry and marine life to produce more food, fuels, fiber and goods.

Ag Biotech in North Carolina There are more than 80 ag biotech companies of all sizes in North Carolina, some with multiple sites in the state, spanning from the mountains (West) to the coast (East/Southeast). These companies are involved in diverse sectors from plant and animal health and productivity to environmental remediation, industrial compounds and human medicines. Many of these companies are experiencing major ag biotech innovation and industry expansions in North Carolina. Five of the six world leaders in ag biotech have operations in North Carolina - BASF Plant Science, Bayer CropScience, DuPont Pioneer, Monsanto and Syngenta. Three have their global or North American headquarters located here - BASF Plant Science, Bayer CropScience, and Syngenta. Novozymes, a leading global industrial and agricultural enzymes company, also has their North American headquarters in the state. More than 8200 North Carolina citizens are employed by ag biotech companies across the state. Additionally, North Carolina is home to more than 934 ag-related support organizations.

NCBiotech Support for Ag Biotech Agricultural Bioscience Company and Entrepreneurial Profile System (AgBIOCEPS) is a database representing a sampling of our state’s entrepreneurial ag biotech companies that have unique technologies in North Carolina. AgBIOCEPS is a tool to bring these companies to the attention of a potential funder, partner, or capital acquirer. The aggregated value of investment opportunities presented is approximately $40 million. NCBiotech has awarded 335 ag biotech grants and 41 ag biotech loans totaling $19,387,177 and $2,801,653, respectively. Every $1 invested in ag-related grants yields $64 in additional funding, and every $1 invested in ag-related loans yields $293 in additional funding.

Overview of Ag Industry in North Carolina North Carolina's agricultural industry, including food, fiber and forestry, contributes $78 billion annually to the State's economy, accounts for 17% of the State's income, and employs over 16% of the work force. North Carolina is one of the most diversified agriculture states in the nation. The state's 50,000 farms grow over 80 different commodities, utilizing 8.5 million of the state's 31 million acres to furnish consumers a dependable and affordable supply of food and fiber. North Carolina’s agricultural industry provides over $11.7 billion in annual cash receipts to the state. North Carolina is ranked by Battelle among the 12 largest states with a “sizable” share of total U.S. employment in agricultural biotechnology. Employment concentration relative to the overall U.S. (location quotient = 1.20) places North Carolina among those considered “specialized” in agriculture. North Carolina awards a rapidly-growing number of agriculture and natural science degrees across the state, more than three times the growth of overall degrees awarded in the state. Additionally, North Carolina receives ag-related federal funding, ranked 7th in FY2012 and has seen an increase in the number of ag biotech-related patents granted.

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

North Carolina Ag Biotech: Economic Growth Report Ag Biotech in North Carolina The AgBiotech Initiative at NCBiotech was formed in January 2010 to stimulate the growth of agricultural biotechnology in North Carolina to create new opportunities that generate jobs, strengthen the economy and produce the technologies and products that help meet the global demand for food, fuel, medicine and sustainable materials. North Carolina is the global hub of ag biotech with tremendous assets driving the development of new innovations in ag biotech, combining the state’s two largest industries – agriculture and biotechnology. Ag biotech applies the tools of biotech to crops, livestock, forestry and marine life to produce more food, fuels, fiber and goods. Ag biotech uses a broad range of scientific techniques including hybridization, genetic modification, marker-assisted breeding, and micropropagation to create products with lower costs and less environmental impact.

Ag Biotech Companies and Employees There are more than 80 ag biotech companies of all sizes in North Carolina, some with multiple sites in the state, working within a number of agricultural sectors (and some in multiple sectors) including1:    

Animal Health and Nutrition (18) Biofuels and Biomass Conversion (13) Crop and Plant Protection (18) Environmental Biotechnology (5)

   

Aquaculture and Marine Sciences (3) Crop and Plant Biotechnology (17) Crop Yield and Health (12) Food Processing and Production (4)

Five of the six world leaders in ag biotech have operations in North Carolina - BASF Plant Science, Bayer CropScience, DuPont Pioneer, Monsanto and Syngenta. Three have their global or North American headquarters located here - BASF Plant Science, Bayer CropScience, and Syngenta. Novozymes, a leading global industrial and agricultural enzymes company, also has their North American headquarters in the state.

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Does not include companies that are pure biotech with no ag focus. 2

North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

North Carolina’s 80+ ag biotech companies span from the mountains (West) to the coast (East/Southeast) with the majority calling the Triangle area home. More than 8200 North Carolina citizens are employed by ag biotech companies across the state.2

Ag Biotech Company Sites in NC, by Region 6, (7%)

8 (9%) 5 (6%)

East Greater Charlotte Piedmont Triad Southeast

13 (14%)

Triangle 55 (61%)

3 (3%)

West

Of the current ag biotech companies/sites in North Carolina, 15 of them (17%) have been founded or relocated to the state since 2010.3 You can find the full list of ag biotech companies and company sites in the online NCBiotech Company Directory: http://ow.ly/rRj9H. Additionally, North Carolina is home to more than 934 ag-related support organizations (not a comprehensive inventory).

Ag Biotech Employees in NC, by Region 410 (5%)

210 (3%)

129 (2%) East

1,147 (14%)

51 (1%)

Greater Charlotte Piedmont Triad Southeast Triangle

5,999 (75%)

West

Note: the figures below show the data split out by company site, therefore the employee totals add up to less than the total employed in North Carolina as a whole. This happens because some of the larger companies count employees acting as telecommuters or doing sales out of their home, working in NC but not at a specific site. 3 Company names, websites, cities, and founding dates can be found in Appendix 1. 2

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

The total number of ag biotech employees in the state has increased from 7400 to 8275 since January 2010 (11.8% growth).

Ag Biotech Employees in NC (since AgBiotech Initiative began 2010) 8400

8275

8200

8058

8000 7751

7800 7600

7403

7400

7470

7200 7000 2010

2011

2012

2013

2014

Prospective Growth in Ag Biotech4 Since 2010, there has been major ag biotech innovation and industry expansions in North Carolina:  Eleven ag biotech companies have announced more than $621 million in prospective investments.  Fifteen ag biotech companies have announced approximately 1475 prospective jobs.  A number of these companies including BASF, Bayer CropScience, and Syngenta have had multiple prospective investment and jobs announcements.

NCBiotech Support for Ag Biotech Agricultural Bioscience Company and Entrepreneurial Profile System AgBIOCEPS is a database representing a sampling of our state’s entrepreneurial ag biotech companies that have unique technologies in North Carolina. Companies profiled are seeking various funding, technology partners or licensing opportunities to grow their technologies and companies. AgBIOCEPS is a tool to bring these companies to the attention of a potential funder, partner, or capital acquirer. The aggregated value of investment opportunities presented is approximately $40 million. To view the companies profiled in the AgBIOCEPS portfolio: www.ncbiotech.org/agbioceps.

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Details about prospective investments and jobs to be created can be found in Appendix 2. 4

North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Ag-focused Biotech Awards Bring High Returns to North Carolina NCBiotech has awarded 335 ag biotech grants and 41 ag biotech loans totaling $19,387,177 and $2,801,653, respectively. For every dollar that the Center provides to award recipients, additional funding is leveraged5.

Overview of Ag Industry in North Carolina6 North Carolina's agricultural industry, including food, fiber and forestry, contributes nearly $78 billion annually to the State's economy, accounts for 17% of the State's income, and employs 640,000 of the state’s four million employees, or about 16% of the workforce.

Agriculture/Agribusiness Value-Added Analysis Dr. Michael L. Walden, Ph.D. is an agricultural and resource economics professor at NC State University and annually publishes an economic analysis of the impact of agriculture and agribusiness on the state. The most recent analysis from Dr. Walden shows that agriculture and agribusiness contributed nearly $78 billion to North Carolina’s economy in 2012, an increase of ten percent since 2007.

NC Agriculture and Agribusiness Income "income" in billion $

80 $77

78 76

$74.3

74 72 70

$77.9

$71.6 $69.6

$70.1

68 66 64 2007

2008

2009

2010

2011

2012

NCBiotech grants awarded and additional funding yielded (based on current research grants) through June 30, 2013. NCBiotech loans awarded and additional funding yielded through June 30, 2014. 6 Walden, Michael. “Agriculture and Agribusiness: North Carolina’s Number One Industry.” NC State University College of Agriculture and Life Sciences, May 2014. http://ag-econ.ncsu.edu/sites/agecon.ncsu.edu/files/faculty/walden/agribusiness-2014.pdf. Details can be found in Appendix 3. 5

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Diversity of Agricultural Production7 North Carolina is one of the most diversified agriculture states in the nation. The state's 50,000 farms grow over 80 different commodities, utilizing 8.5 million of the state's 31 million acres to furnish consumers a dependable and affordable supply of food and fiber. North Carolina produces more tobacco and sweet potatoes than any other state and ranks second in Christmas tree cash receipts, and the production of hogs and turkeys. The state ranks sixth nationally in farm profits with a net farm income of over $4.3 billion. Net income per farm in the state is over $86,000.8 North Carolina’s agricultural industry provides over $11.7 billion in annual cash receipts to the state, from a wide variety of crops.

National rankings show that North Carolina is highly competitive in the following production areas; #1 – tobacco and sweet potatoes #2 – hogs, trout, turkeys, all poultry/egg, and Christmas trees #3 – cucumbers (for both processing and fresh market) #4 – broilers, upland cotton, fresh market tomatoes and fresh market strawberries #5 – catfish, peanuts, bell peppers, squash and greenhouse/nursery crops North Carolina farm income ranks 8th in overall livestock, dairy and poultry, and 19th in overall crops. North Carolina ranks 10th in the nation in total farm income. “2013 Agricultural Statistics Book.” North Carolina Department of Agriculture and Consumer Services, January 2014. http://www.ncagr.gov/stats/2013AgStat/index.htm Original source of data includes the USDA Economic Research Service. 8 “Farm Income and Wealth Statistics: Net farm income by State rank, 2012.” USDA Economic Research Service. Updated as of 11 February 2014. Accessed online 8 April 2014. http://www.ers.usda.gov/data-products/farm-income-andwealth-statistics/ranking-net-value-and-farm-income.aspx#.U0RW-PnER5U [income per farm calculated] 7

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Agricultural Feedstock & Chemicals Sector Analysis Every two years, Battelle and BIO publish a comparison of states based on various sectors of biotechnology.9 Here are the most recent results for North Carolina’s “Agricultural Feedstock & Chemicals” sector:

North Carolina is ranked among the 12 largest states with what Battelle defines as a “sizable” share of total U.S. employment in this sector. Employment concentration relative to the overall U.S. (location quotient = 1.48) places North Carolina among those considered “specialized” in agriculture. NOTE: location quotient increased from 1.20 in 2010 to 1.48 in 2012.

Battelle/BIO State Bioscience Jobs, Investments and Innovation 2014 (based on 2012 statistics), p.15. http://www.bio.org/sites/default/files/Battelle-BIO-2014-Industry.pdf. Agricultural Feedstock & Chemicals Sector Analysis’ NAICS Codes can be found in Appendix 4. 9

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Ag-related Degrees Awarded North Carolina has experienced significant growth in the number of students earning bachelor’s, master’s and doctoral degrees in agriculture and natural sciences.10

Over the past six years (since 2008), there has been a 52% percent increase in agriculture and natural sciences degrees – more than twice the growth of overall degrees awarded in the state.

Growth in Degrees Awarded 60% 50%

52%

40% 30%

34%

36%

20%

21%

10% 0% Agriculture & Natural Resources

All Life Science

Science & Engineering

All Disciplines

2013-2014 Statistical Abstract of Higher Education, published by UNC General Administration, August 2014. http://www.northcarolina.edu/apps/stat_abstract/index.php 10

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Federal Ag-related Grant Funding for North Carolina Federal dollars coming into the state from the National Science Foundation (NSF) and United States Department of Agriculture (USDA), the major federal funders of ag-related projects, totaled nearly $180 million in FY 2012. North Carolina ranks seventh, among the states in NIH funding, with just over $1 billion in funding in FY 2012. Agency NSF USDA ALL Federal Grants

Dollars (FY 2012) $ 159,964,000 $ 18,725,959 15.7 billion

State Ranking 12 13 7

For the past few years, federal funding from NSF and USDA has shown a gradual increase. USDA funding to the state has experienced some ups and downs over past years, but appears to be increasing as a general trend.

NSF and USDA Funding to NC $200,000,000 $180,000,000 $160,000,000 $140,000,000 $120,000,000 $100,000,000 $80,000,000 $60,000,000 $40,000,000 $20,000,000 $-

USDA Funding to NC $35,000,000 $30,000,000 $25,000,000

USDA NSF

$20,000,000 $15,000,000 $10,000,000 $5,000,000 $-

2010

2011

2012

2006 2007 2008 2009 2010 2011 2012

The high USDA funding shown above for 2011 is likely due to a $25 million grant awarded to North Carolina State University for the study of food-borne illnesses. The grant was awarded through the National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) competitive grants program to PI LeeAnn Jaykus and an established a consortium with other universities, providing a portion of the funding to other states.11

11

http://www.nifa.usda.gov/newsroom/news/2011news/08031_norovirus.html 9

North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Plant-related Patents Granted in North Carolina12 The number of plant-related patents granted per year in the state has nearly doubled since 2006 - from 52 to 98 patents.

Plant-related Patents Granted in NC 120

Year Granted

Plant Patents

2006

52

100

2007

66

80

2008

61

2009

84

60

2010

98

40

2011

94

2012

87

2013

98

20 0 2006

2007

2008

2009

2010

2011

2012

2013

Note: Unfortunately, in the patent classification schema, animal and human health products and services (drugs, devices, and procedures) are not distinguished from each other. Therefore, the only specific agrelated patent statistics that can be extracted are the plant-related ones. Further explanation can be found in Appendix 4. The patent search is conducted by assignee state or inventor state: North Carolina. An “assignee” is the individual or entity to which ownership of the patent was assigned at the time of patent issue. When a company or university is involved in filing the patent, they are usually listed as “assignee”, while any individuals are listed as “inventor”. In the Battelle/BIO report, 13 states were ranked by classes of bioscience-related patents. North Carolina is in the top 10 states for what they call “Agricultural Bioscience” patents. The patent classification codes used by Battelle in this analysis include 71 (Chemistry: fertilizers); 504 (Plant protecting and regulating compositions); and PLT (Plants).

In-house analysis, data gathered from U.S. Patent and Trademark Office, see Appendix 5 for patent classification codes and search strategies used. http://patft.uspto.gov/netahtml/PTO/search-adv.htm 13 Battelle/BIO State Bioscience Jobs, Investments and Innovation 2014, p.49. http://www.bio.org/sites/default/files/Battelle-BIO-2014-Industry.pdf 12

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Appendix 1: Ag Biotech Companies/Sites Founded or Relocated to NC since 2010 Company Name

City

AgBiome Inc. Benson Hill Biosystems Inc. BioDeptronix BotaniPharm LLC EntoGenex Biotechnology LLC FMC Corp. (acquired RTI's Center for Medicago USA Inc. Nova Synthetix Inc. Ovation Biotech Inc. Plant Health Care Inc. Precision PlantSciences Inc. Triad BioGreen Technologies Inc. TyraTech Inc. Verdesian Life Sciences LLC Zoion Pharma Inc.

Ag and Environmental Biosolutions)

Primary Employment Activity* Range

Research Triangle Park Research Triangle Park Chapel Hill Candler Chapel Hill Research Triangle Park

Year Founded/ Relocated 2013 2012 2012 2011 2011 2013

R&D R&D R&D R&D R&D R&D

1-20 1-20 1-20 1-20 1-20 1-20

Research Triangle Park Chapel Hill Raleigh Raleigh Durham Greensboro Morrisville Cary Raleigh

2010 2012 2010 2013 2012 2011 2011 2013 2011

R&D R&D P&M R&D R&D P&M R&D R&D R&D

51-100 1-20 1-20 1-20 21-50 1-20 1-20 1-20 1-20

* R&D = Research and Development, CR&T = Contract Research & Testing, P&M = Production and Manufacturing

Pending ag biotech companies and/or sites to be added to the table above in the April report as company and employee information is reported.    

Biological Applied Research Edison Agrosciences Inc. Global Future Solutions (GFS) Agri Corp. Novozymes BioAg

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Appendix 2: Full Prospective Growth Report Prospective Ag Biotech Investments Full Name / Company / Person Alexandria Center for Ag, Science and Technology – RTP (formerly Alexandria Ag-

Prospective Investment Announcement $20,000,000

Date (approximate)

Project

3/18/2014

Convergence Campus (at RTP Expansion - Plant Biotechnology and Crop Protection Research Greenhouse 5 Land Purchase Bee Care Center North American HQ Renovation Greenhouse 1 Production Center R&D Facility

The Hamner Institutes)

Tech Center)

BASF Corp.

$33,000,000

2/15/2012

Bayer CropScience LP Bayer CropScience LP Bayer CropScience LP Bayer CropScience LP

$20,000,000 $2,200,000 $33,000,000 $6,200,000

3/2/2011 12/20/2012 5/30/2013 10/17/2013

Bayer CropScience LP Carolina Cellulosic Biofuels LLC DuPont Pioneer - Kinston Research Center Greer Laboratories Inc. Medicago USA Inc. Novozymes Piedmont Pharmaceuticals LLC Syngenta Biotechnology Inc. Syngenta Biotechnology Inc. Tyton NC Biofuels LLC

$29,600,000 $200,000,000 $2,300,000

6/30/2014 12/2/2013 5/17/2011

$30,000,000 $7,500,000 $36,000,000 $279,000 $71,000,000 $94,000,000 $36,000,000

9/24/2013 8/10/2010 4/24/2014 9/17/2012 5/20/2011 7/30/2013 6/3/2014

TOTAL PROSPECTIVE INVESTMENT ANNOUNCEMENTS

$621,079,000

12

HQ Expansion RTP Facility Bio Ag R&D Facility HQ Expansion Advanced Crop Lab Lab and Offices Ethanol Production Plant and R&D Lab

North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Prospective Ag Biotech Job Announcements Full Name / Company / Person

Date Project (approximate)

Advanced Animal Diagnostics Inc. BASF Corp.

Prospective Jobs Announcement 5 123

BASF Corp.

30

1/11/2013

Bayer CropScience LP Bayer CropScience LP Bayer CropScience LP

25 100 100

3/1/2011 5/30/2013 10/18/2013

Carolina Cellulosic Biofuels LLC Chemtex

65 300

12/2/2013 7/9/2013

DuPont Pioneer - Kinston Research Center Greer Laboratories Inc. Medicago USA Inc. Novozymes Piedmont Pharmaceuticals LLC Plant Health Care Inc. FMC Corp. (acquired RTI's Center for Ag and

10

5/17/2011

125 85 100 14 9 10

9/24/2013 8/10/2010 4/24/14 9/17/2012 7/9/2013 12/16/2011

Syngenta Biotechnology Inc. Syngenta Biotechnology Inc. Syngenta Biotechnology Inc. TyraTech Inc. Tyton NC Biofuels LLC

15 25 150 105 79

5/20/2011 7/27/2012 7/30/2013 3/1/2011 6/3/2014

TOTAL PROSPECTIVE JOB ANNOUNCEMENTS

1475

Environmental Biosolutions)

13

2/1/2012 1/17/2012

Launch of first product Plant science HQ move to RTP Pest control business move to RTP Greenhouse Bee Care Center North American HQ Renovation Production Center Ethanol Refinery Sampson County R&D facility HQ expansion RTP facility Bio Ag R&D Facility HQ expansion Center for Agriculture and Environmental Biosolutions (CAEB) Advanced Crop Lab Expansion New lab and offices Relocation to NC Ethanol Production Plant and R&D Lab

North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Appendix 3: North Carolina Agriculture and Agribusiness Income Economic Analysis 2009-2014 (data from 2007-2012) ("income" in billions $) Agriculture/Food Industries Farming Manufacturing Wholesaling Retailing Total Fiber Industries Manufacturing Wholesaling Retailing Total Forestry Farming Manufacturing Wholesaling Retailing Total

2007

2008

2009

2010

2011

2012

13.5 22.3 6 15.6 57.4

14.4 23.5 6.7 16.9 61.5

13.6 20.2 6.3 18.4 58.5

14.1 22.9 6.9 18.3 62.2

14.9 25.8 7.6 19.1 67.4

16.1 27.5 5.8 16.8 66.2

2.6 0.8 2.8 6.2

2.6 0.8 2.9 6.3

2.1 0.8 2.6 5.5

1.9 0.9 1.1 3.9

1.9 0.9 1.2 4

2.1 0.9 1.6 4.6

0.8 5.7 6.5

0.8 5.7 6.5

0.6 5 5.6

0.9 4.6 5.5

0.8 4.8 5.6

0.2 3.9 2.3 0.7 7.1

Grand Total

70.1

74.3

69.6

71.6

2007 13.5 0.8 14.3

2008 14.4 0.8 15.2

2009 13.6 0.6 14.2

2010 14.1 0.9 15

77 2011 source 2011 14.9 0.8 15.7

77.9 2012 source 2012 16.1 0.2 16.3

Farming alone

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Appendix 4: Battelle Analysis Battelle's Agricultural Feedstock & Chemicals Sector Analysis’ NAICS Codes 311221 311222 311223 325193 325221

Wet corn milling Soybean processing Other oilseed processing All other basic organic chemical manufacturing Cellulosic organic fiber manufacturing

325311 325312 325314 325320

Nitrogenous fertilizer manufacturing Phosphatic fertilizer manufacturing Fertilizer (mixing only) manufacturing Pesticide and other agricultural chemical manufacturing

Leading States Bioscience-Related Patents by Class Group, 2009-2013 Note: A shaded circle signifies the state ranks in the top 5, and an open circle signifies the state ranks in the next 5 for that particular patent class.

http://www.bio.org/articles/battellebio-state-bioscience-jobs-investments-and-innovation-2014 (June 2014)

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Appendix 5: Patent Classification Plant-related Patent Classification Codes Class 047 Class 071 Class 435/410 Class 504 Class 800 Class PLT

Plant Husbandry Chemistry: fertilizers Plant cell culture Plant protecting and regulating compositions Multicellular living organisms and unmodified parts thereof and related processes Plants

Example of search query, for 2013: (ccl/047/$ or ccl/504/$ or ccl/800/$ or ccl/PLT/$ or ccl/71/$ or ccl/435/410) and (is/nc or as/nc) and isd/$/$/2013 In the patent classification schema, animal and human health products and services (drugs, devices, and procedures) are not distinguished from each other. Therefore, the only specific ag-related patent statistics that can be extracted are the plant-related ones. 



Keywords could be used for searching, but with patents this is not recommended – not only because of the large number of keywords and synonyms that would need to be determined, but also because of the nature of patent writing. Patents are often filed with intentionally unclear language in order to ‘hide’ the technological processes from competitors. Animal Husbandry (113) is a distinct classification code - “this class provides for methods or apparatus for the propagation, rearing, training, exercising, amusing, feeding, milking, grooming, housing, controlling, handling, or general care of a living animal unless provided for elsewhere.” This one category could be included, but would not be representative of all animal agriculture.

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

Appendix 6: Schedule for Updates Quarterly Updates The following updates are made every quarter and are include in each quarterly NC Ag Biotech Economic Growth Report:  Prospective Growth in Ag Biotech (including Appendix 2)

Annual Updates The following updates are made annually or biennially in the quarter indicated, prior to the release of the NC Ag Biotech Economic Growth Report.

First Quarter (January – March)     

Ag Biotech Companies and Employees Ag Biotech Companies Founded/Relocated to NC (including Appendix 1) Diversity of Agricultural Production Federal Ag-related Grant Funding - NSF Ag-related Patents Granted

Second Quarter (April – June)    

Agricultural Bioscience Company and Entrepreneurial Profile System Agricultural Feedstock & Chemicals Sector Analysis Agriculture/Agribusiness Value-Added Analysis Federal Ag-related Grant Funding - USDA

Third Quarter (July – September)  

Ag-focused Awards Bring High Returns to North Carolina Ag-related Degrees Awarded

Fourth Quarter (October - December)

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North Carolina Ag Biotech: Economic Growth Report | North Carolina Biotechnology Center

UNC-W/Jamie Moncreif

Steve McKeand/treeimprovement.org

Syngenta

istockphoto.com

NCBiotech is a private, non-profit corporation supported by the N.C. General Assembly. Its mission is to provide longterm economic and societal bene its to North Carolina by supporting biotechnology research, business, education and strategic policy statewide. The North Carolina AgBiotech Initiative stimulates the growth of agricultural biotechnology in the state of North Carolina to create new opportunities that generate jobs, strengthen the economy and produce the technologies and products that help meet the global demand for food, fuel, medicine and sustainable material. www.ncbiotech.org/agbiotech

15 T.W. Alexander Drive · P.O. Box 13547 · Research Triangle Park, NC 27709-3547 · ncbiotech.org Asheville · Charlotte · Greenville · Research Triangle Park · Wilmington · Winston-Salem

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