Neglected Tropical Diseases A statistical update – latest data available
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A statistical update – latest data available
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Buruli ulcer Distribution of Buruli ulcer, worldwide, 2013
Distribution of Buruli ulcer, worldwide, 2013
Number of reported cases, 2013 > 1 000
No cases reported
500 999
Previously reported cases
100 499
Not applicable
< 100 The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Number of Buruli ulcer cases reported to WHO, by region, 2005–2013 6 000
5 000
Number of new cases detected
4 000
3 000
2 000
1 000
0 2005 2006 2007 2008 2009 2010 2011 2012 2013
Year
African Region South-East Asia Region
Region of the Americas Western Pacific Region
Eastern Mediterranean Region
2005 2006 2007 2008 2009 2010 2011 2012 2013
AFR
4 674
5 265
4 935
5 079
5 029
4 846
3 841
3 104
2 543
AMR 2 2 2 8 2 7 3 2 3 EMR 24 38 8 3 5 4 WPR 48 73 90 66 48 56 161 105 84
Global
4 748
5 378
5 035
5 156
5 084
4 913
4 005
3 211
2 630
AFR–African Region / AMR–Region of the Americas / EMR–Eastern Mediterranean Region / WPR–Western Pacific Region
1
neglected tropical diseases
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chagas disease
Distribution of Chagas disease cases, based on official estimates, worldwide, 2010–2013
Estimated number of T. cruzi infected cases < 900
No data available
900 89 999
Not applicable
90 000 899 999 > 900 000
Estimated prevalence of Chagas disease, by official source, 1960–2014 Millions
30
25
20
15
10
5
Latin American Initiatives
DCPP: Disease Control Priorities Project; NEC: non-endemic countries
NEC Initiative
WHO
WHO
WHO
PAHO/WHO
Schmunis
World Bank/DCPP
Year and source
Schmunis
Schmunis
WHO
PAHO
WHO
WHO
WHO
Waslh
PAHO
WHO
WHO
0 1960 1976 1981 1984 1985 1990 1991 1992 1992 1994 1999 1999 2000 2006 2006 2010 2013 2014 WHO
2
Estimated prevalence
A statistical update – latest data available
***
dengue Distribution of countries or areas at risk of dengue transmission, worldwide, 2013
Distribution of countries or areas at risk of dengue transmission, worldwide, 2013
January isotherm
July isotherm
Countries or areas at risk of dengue transmission Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
The contour lines of the January and July isotherms indicate areas at risk, defined by the geographical limits of the northern and southern hemispheres for year-round survival of Aedes aegypti, the principal mosquito vector of dengue viruses
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Millions
Number of dengue cases reported to WHO, by region, 1995–2013
Number of cases reported
3.5 3 2.5 2 1.5 1 0.5 0 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013
Year
Eastern Mediterranean Region Western Pacific Region
Region of the Americas
South-East Asia Region
10 °C
10 °C
3
4
neglected tropical diseases
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Number of dengue deaths reported to WHO, worldwide, 2000–2013 4 500 4 000
Number of deaths reported
3 500 3 000 2 500 2 000 1 500 1 000 500 0
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013
Year
A statistical update – latest data available
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Dracunculiasis (guinea-worm disease) Countries endemic for dracunculiasis, 1989 and 2013
1989
2013
Countries endemic for dracunculiasis
Not applicable
Number of dracunculiasis cases reported to WHO, by month, 2012–2014
140 120
Number of cases reported
100 80 60 40 20 0
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
Month 2012 a
2013
2014
Data for 2014 are provisional up to September.
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
2012 2 5 55 82 125 128 71 32 22 14 4 2
2013 1 2 4 29 33 23 17 12 13 5 7 2
2014 1 1 4 5 5 11 25 22 26
5
6
neglected tropical diseases
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Status of global certification of dracunculiasis eradication, 2013
Countries currently endemic for dracunculiasis
Not applicable
Countries in the precertification stage Previously endemic countries certified free of dracunculiasis Other countries and territories certified free of dracunculiasis Countries and territories not known to have dracunculiasis but yet to be certified
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A statistical update – latest data available
Echinococcosis Distribution of Echinococcus granulosus and cystic echinococcosis, worldwide, 2012
Distribution of Echinococcus granulosus and cystic echinococcosis, worldwide,2012
Highly endemic areas
Rare/sporadic
Present
Probably absent
Suspected
Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
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neglected tropical diseases
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Endemic treponematoses Distribution of yaws, worldwide, 2013 Distribution of yaws, worldwide, 2008-2013
Number of reported cases of yaws, 2008-2013, latest year available ≥ 10 000 Previously endemic (current status unknown)
1 000–9 999
No previous history of yaws
< 1 000
Not applicable Transmission interrupted The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Number of yaws cases reported to WHO, 2008–2013 Thousands
8
90 80 70
Number of cases reported
60 50 40 30 20 10 0 2008 2009 2010 2011 2012 2013
Year
Number of cases reported
Global
2008 2009 2010 2011 2012 2013 56 223
69 467
80 226
51 101
49 375
58 915
***
Foodborne trematodiases Distribution of clonorchiasis, worldwide, latest year available
Distribution of clonorchiasis, worldwide, latest year available
Countries with reported cases of Clonorchis sinensis infection No data available Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Distribution of opisthorchiasis, worldwide, latest year available
Distribution of opisthorchiasis, worldwide, latest year available
Countries with reported cases of Opisthorchis viverrini infection Countries with reported cases of Opisthorchis felineus infection Countries with reported cases of Opisthorchis viverrini and Opisthorchis felineus infections No data available Not applicable The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
A statistical update – latest data available
9
10
neglected tropical diseases
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Distribution of fascioliasis, worldwide, latest year available
Distribution of fascioliasis, worldwide, latest year available
Countries with reported cases of Fasciola spp. infection No data available Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Distribution of paragonimiasis, worldwide, latest year available
Distribution of paragonimiasis, worldwide, latest year available
Countries with reported cases of Paragonimus spp. infection No data available Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
A statistical update – latest data available
***
Human African trypanosomiasis (sleeping sickness) Distribution of human African trypanosomiasis (T.b. gambiense), worldwide, 2013
Distribution of human African trypanosomiasis (T.b.gambiense), worldwide, 2013
Number of reported cases, 2013 > 1 000
Endemic countries (no data available)
100 1 000
Non T.b.gambiense endemic countries
< 100
Not applicable
0 cases reported The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Distribution of human African trypanosomiasis (T.b. rhodesiense), worldwide, 2013
Distribution of human African trypanosomiasis (T.b.rhodesiense), worldwide, 2013
Number of reported cases, 2013 < 100
Endemic countries (no data available)
0 cases reported
Non T.b.rhodesiense endemic countries Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
11
neglected tropical diseases
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Number of human African trypanosomiasis cases reported to WHO, 1990–2013 Thousands
12
40 35 30
Number of cases reported
25 20 15 10 5 0 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012
Year
T.b. gambiense
12 756 10 987 14 088 16 607 23 266 23 671 28 736 36 585 37 385 27 862 25 865 26 117 1933 1219 1147 831 711 935 591 592 606 619 709 755 T.b. gambiense
T.b. rhodesiense
1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001
T.b. rhodesiense
2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 23 836 19 963 17 130 15 644 11 382 10 473 10 388 9 685 6 978 6 637 7 106 6 228 617 536 552 710 453 305 259 190 156 113 110 86
A statistical update – latest data available
***
Leishmaniases Distribution of visceral leishmaniasis, worldwide, 2012
Status of endemicity of visceral leishmaniasis, worldwide, 2012
Number of new cases reported, 2012 > 1 000 100 1 000
No data available
< 100
Not applicable
0 No autochthonous cases reported
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Distribution of cutaneous leishmaniasis, worldwide, 2012
Status of endemicity of cutaneous leishmaniasis, worldwide, 2012
Number of new cases reported, 2012 > 5 000 1 000 4 999
No data available
< 1 000
Not applicable
0 No autochthonous cases reported
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
13
neglected tropical diseases
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Number of cases reported
Thousands
Number of cutaneous leishmaniasis cases reported to WHO, by region, 2003–2012 250
200
150
100
50
0 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
Year
African Region European Region
Region of the Americas Western Pacific Region
Eastern Mediterranean Region South-East Asia Region
2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
22 292 17 404 31 159 15 304 7 052 8 513 10 666 10 173 14 159 9 057 AMR 65 909 63 397 71 866 65 581 62 653 55 558 60 326 61 311 56 794 50 060 EMR 77 017 98 729 97 344 93 910 94 425 99 466 124 143 121 403 139 363 131 865 EUR 3 758 5 305 2 967 2 717 2 658 2 421 2 271 3 150 10 3 SEAR 232 248 386 405 540 572 513 148 0 0 WPR 0 0 0 0 0 1 3 0 0 0 Total 169 208 185 083 203 722 177 917 167 328 166 531 197 922 196 185 210 326 190 985 AFR
AFR–African Region / AMR–Region of the Americas / EMR–Eastern Mediterranean Region / EUR–European Region / SEAR–South-East Asia Region / WPR–Western Pacific Region
Number of visceral leishmaniasis cases reported to WHO, by region, 2003–2012 Thousands
14
Number of cases reported
70 60 50 40 30 20 10 0 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
Year
African Region European Region
Region of the Americas Western Pacific Region
Eastern Mediterranean Region South-East Asia Region
2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
8 610 6 032 6 623 3 965 2 652 2 584 3 231 11 270 14 458 8 126 AMR 3 166 3 783 3 753 3 825 3 780 4 003 3 878 3 952 4 005 3 214 EMR 10 230 6 289 6 165 3 729 4 100 5 339 7 265 9 107 7 029 4 924 EUR 776 868 864 771 890 669 363 556 340 131 SEAR 26 556 31 987 41 158 50 091 50 900 39 813 29 333 32 898 37 260 23 048 WPR 0 351 335 294 382 529 539 402 293 218 Total 49 338 49 310 58 898 62 675 62 704 52 937 44 609 58 185 63 385 39 661 AFR
AFR–African Region / AMR–Region of the Americas / EMR–Eastern Mediterranean Region / EUR–European Region / SEAR–South-East Asia Region / WPR–Western Pacific Region
A statistical update – latest data available
***
Thousands
Top six high-burden countries for visceral leishmaniasis, 2003–2012
Number of cases reported
70 60 50 40 30 20 10 0 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
Year Top six high-burden countries (HBC) Bangladesh India Nepal
2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
Bangladesh
6 113
5 920
6 892
9 379
4 932
4 840
4 293
3 800
3 376
1 902
Brazil
2 971
3 580
3 597
3 651
3 604
3 852
3 693
3 716
3 840
3 118
Ethiopia
NA
1 403
2 585
2 375
1 579
1 356
1 083
1 936
2 032
2 500
India
18 214
24 479
32 803
39 173
44 533
33 598
24 213
28 382
33 155
20 571
South Sudan
7 722
3 777
3 141
1 117
758
582
1 907
9 166
11 862
5 012
Sudan
704
2 619
3 713
1 827
2 788
3 310
4 880
6 957
5 226
3 165
Top 6 HBC
42 324
41 778
52 731
57 522
58 194
47 538
40 069
53 957
59 491
36 268
15
16
neglected tropical diseases
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LePROSY New case-detection rates for leprosy, data reported to WHO as of January 2014
Leprosy new case detection rates, data reported to WHO as of January 2014
New case detection rates (per 100 000 population) > 10
Not reported
1.0 10.0
Not applicable
2
Not reported
1.0 2.0
Not applicable
20%) Hypo-endemic (prevalence < 20%) Endemic countries (former OCP countries) Non-endemic countries Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Millions
Number of people treated and global coverage of preventive chemotherapy for onchocerciasis, by WHO region, 2008–2012 90
120
80 100
80
60 50
60 40 40
30 20
20 10 0 2008 2009 2010 2011 2012
0
Year
African Region Global coverage
Region of the Americas
Eastern Mediterranean Region
Global coverage (%)
70
Number of people treated
19
neglected tropical diseases
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Rabies Distribution of risk to humans of contracting rabies, worldwide, 2013
Distribution of risk levels for humans contacting rabies, worldwide, 2013
High risk Moderate risk Low risk No risk No data available Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Number of human rabies cases compared with animal rabies cases in KwaZulu-Natal (South Africa), 2007–2014 500
7
450 6 400 5
350 300
4
250 3
200 150
2
100 1
50
0 2007 2008 2009 2010 2011 2012 2013 2014
Year
Human rabies
Animal rabies
0
Number of animal rabies cases
20
Number of human deaths reported
***
Number of humans potentially exposed to rabies and presenting for postexposure prophylaxis, 2010–2013 100
Percentage of intradermal administration use versus intramuscular
80
60
40
20
0 January January January January 2010 2011 2012 2013
Year
Human rabies
A statistical update – latest data available
21
neglected tropical diseases
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Schistosomiasis Distribution of schistosomiasis, worldwide, 2012
Distribution of schistosomiasis, worldwide, 2012
High (prevalence > 50%) Moderate (prevalence 10% 49%) Low (prevalence < 10%)
Countries requiring evaluation of schistosomiasis status in order to verify if interruption of transmission has been achieved Non-endemic countries Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Number of people treated and global coverage with preventive chemotherapy for schistosomiasis, by WHO region, 2008–2012 45
16
40
14
35
12
30
10
25 8 20 6
15
4
10 5
2
0 2008 2009 2010 2011 2012
0
Year
African Region South-East Asia Region Global coverage
Region of the Americas Western Pacific Region
Eastern Mediterranean Region European
Global coverage (%)
Millions
22
Number of people treated
A statistical update – latest data available
***
Soil-transmitted helminthiases Distribution of soil-transmitted helminthiases and proportion of children (aged 1–14 years) in eeach endemic country
Proportion of children (1-14 years age) inworldwide, the country requiring preventive chemotherapy for theof diseases, 2012requiring preventive chemotherapy (PC) for soil-transmitted helminthiases, worldwide, 2012
> 2/3
No data available
1/3 2/3
Not required
< 1/3
Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
140
40
120
35 30
100
25 80 20 60 15 40
10
20
5
0 2008 2009 2010 2011 2012
0
Year
African Region South-East Asia Region Global coverage
Region of the Americas Western Pacific Region
Eastern Mediterranean Region European Region
Global coverage (%)
Millions
Number of preschool-aged children treated and global coverage of preventive chemotherapy for soil-transmitted helminthiases, by WHO region, 2008–2012
Number of people treated
23
neglected tropical diseases
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Number of school-aged children treated and global coverage of preventive chemotherapy for soil-transmitted helminthiases, by WHO region, 2008–2012 Millions
40
300
35
250
30 200
25 20
150
15
100
10 50
5
0 2008 2009 2010 2011 2012
0
Year
African Region South-East Asia Region Global coverage
Region of the Americas Western Pacific Region
Eastern Mediterranean Region European
Global coverage (%)
24
Number of people treated
***
Taeniasis and (neuro)cysticercosis Countries and areas at risk of cysticercosis, 2012
Countries and areas at risk of cysticercosis, 2012
Endemic (full life-cycle) Suspected endemic Imported cases (possible human cysticercosis transmission) No data available Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
A statistical update – latest data available
25
neglected tropical diseases
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Trachoma Distribution of trachoma, worldwide, 2012
Distribution of trachoma, worldwide, 2012
Countries or areas endemic for blinding trachoma Countries or areas under surveillance Not applicable
The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved
Data Source: World Health Organization Map Production: Control of Neglected Tropical Diseases (NTD) World Health Organization
Number of people treated and global coverage of azithromycin for trachoma, by WHO region, 2008–2012 25
60
50
20
40 15 30 10 20 5
10
0 2008 2009 2010 2011 2012
0
Year
African Region South-East Asia Region Global coverage
Region of the Americas Western Pacific Region
Eastern Mediterranean Region
Global ocverage (%)
Millions
26
Number of people treated
***
A statistical update – latest data available
27