Monthly Healthcare Review June 2016

Monthly Healthcare Review June 2016 IPOs The following table includes the medical devices, biotechnology, pharmaceuticals, and healthcare IPO pricings...
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Monthly Healthcare Review June 2016 IPOs The following table includes the medical devices, biotechnology, pharmaceuticals, and healthcare IPO pricings, filings and withdrawals announced over the previous month.

Company Name

Last Financing Date

HQ Location

Description

Last Financing Size (Millions)

Bioventus (BIOV)

30-Jun-2016

Clearside Biomedical (CLSD)

02-Jun-2016

Kadmon Corporation (KDMN)

10-Jun-2016

Mereo Biopharma (MPH)

09-Jun-2016

London, United Developer and researcher of medicines and pharmaceutical products that focus on Kingdom acquisition and rapid development of innovative medicines.

21.49

Denise ScotsKnight

Moleculin (MBRX)

02-Jun-2016

Houston, TX

9.24

Walter Klemp

NantHealth (NH)

02-Jun-2016

Culver City, CA Provider of cloud-based intelligent clinical operating systems that reduces the administrative 91.00 time and tasks associated with obtaining preauthorization.

Patrick Soon-Shiong

OrthoPediatrics (KIDS) 16-Jun-2016

Warsaw, IN

Mark Throdahl

Oventus

16-Jun-2016

Indooroopilly, Developer of an oral device to treat sleep-disordered breathing. The company offers an oral 8.79 Australia mouth guard that advances the lower jaw and has a separate airway which delivers air directly to the back of the throat, bypassing the tongue and soft palate.

Neil Anderson

Selecta Biosciences (SELB)

22-Jun-2016

Watertown, MA

Werner Cautreels

Compiled by: Terence Yen Source: Pitchbook

Durham, NC

Developer of ultrasound bone growth stimulators/bone healing systems, osteoarthritis pain 150.00 treatments/joint fluid therapies and hyaluronic acid injections. Alpharetta, GA The company provides a non-surgical application for dosing drugs to distinct eye tissues, 50.40 such as retina, trabecular meshwork and corneal stroma, through an ocular micro injection platform. New York, NY Developer of biopharmaceutical products and services for the treatment and management 140.00 of hepatitis C.

Lead Manager

The company offers a therapeutic approach to proliferative skin diseases, including psoriasis, atopic dermatitis, actinic keratosis, and several skin cancers.

The company's products are used to treat fractures, extension osteotomy/crouch gait, 75.00 slipped capital femoral epiphysis, rotational limb deformity, femoral ante version correction, tibial torsion correction, unicameral bone cyst and Blount's disease.

The company's proprietary technology platform of synthetic vaccine particles is a product engine for the durable and antigen-specific treatment of undesired immune responses, focused on three key applications- inhibition of immunogenicity for protein therapies, treatment of allergies and treatment of autoimmune diseases.

70.00

Anthony Bihl III Daniel White

Harlan Waksal

1

Monthly Healthcare Review June 2016 IPOs The following table includes the medical devices, biotechnology, pharmaceuticals, and healthcare IPO pricings, filings and withdrawals announced over the previous month.

Company Name

Last Financing Date

Sensus Healthcare

03-Jun-2016

Syros Pharmaceuticals (SYRS)

30-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

HQ Location

Description

Last Financing Size (Millions)

Boca Raton, FL The company engages in the design, manufacturing and marketing of proprietary low energy 11.00 x-ray radiation technology and superficial radiation therapy to treat non-melanoma skin cancer. Cambridge, MA Developer of medicines that control the expression of genes. The company has developed a 50.00 proprietary gene control platform that provides lens to identify crucial genes that become dysregulated in diseased cells.

Lead Manager

Joseph Sardano

Nancy Simonian

2

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Round

Description

Last Financing Size (Millions)

3DBiopsy

23-Jun-2016

Aurora, CO

Angel (individual)

AccuraGen

02-Jun-2016

Menlo Park, CA

Acera Surgical

01-Jun-2016

St. Louis, MO

Adhesys Medical

21-Jun-2016

Aachen, Germany

Adient Medical

21-Jun-2016

Pearland, TX

Early Stage VC The company provides a mutation detection system, with NSG based technology, using circulating DNA from blood samples for cancer molecular diagnosis. Angel Developer of implantable electrospun neurosurgical meshes and related (individual) tools and accessories. Accelerator/ Manufacturer of medicinal adhesives. The company develops and Incubator commercializes biodegradable surgical adhesives that can be used on the skin and inside the human body to close wounds. Accelerator/ The company develops absorbable medical devices that do not need to Incubator be removed after surgery and can vanish without intervention.

ADL Gruppe

01-Jun-2016

Advanced Osteotomy 07-Jun-2016 Tools

Munster, Germany PE Growth/ Expansion Allschwil, Later Stage VC Switzerland

The company provides products used in treatment of chronic wounds and ulcers. The company develops medical devices for osteotomy pursuing the vision of contact-free bone surgery using laser, robotics and navigation systems to re-invent bone surgery.

Advantagene

13-Jun-2016

Auburndale, MA

Angel (individual)

The company focuses on preventing the recurrence and progression of cancer through the use of therapeutics in oncology and immunotherapy.

Aegle Gear

06-Jun-2016

Chattanooga, TN

Angel (individual)

Provider of health care apparel.

0.75

Undisclosed

Affinity Biosensors

22-Jun-2016

Santa Barbara, CA

Angel (individual)

Developer of particle metrology systems. The company develops analytical instruments for use in research, manufacturing and life sciences based on the company’s Resonant Mass Measurement device.

5.26

Undisclosed

Compiled by: Terence Yen Source: Pitchbook

The company 3D imaging technology that enables medical practitioners 1.35 to diagnose and treat patients suspected of having prostate cancer.

Lead Investor(s)

Undisclosed

40.00

Decheng Capital, StartX, Junson Capital Undisclosed Undisclosed Undisclosed MedTech Innovator

Undisclosed MedTech Innovator

Undisclosed BE Beteiligungen Fonds 8.00 SHS Gesellschaft fur Beteiligungsmanage ment, Zurcher Kantonalbank 9.96 Undisclosed

3

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Round

Description

Last Financing Size (Millions)

Lead Investor(s)

AFFiRiS

23-Jun-2016

Vienna, Austria

Later Stage VC The company develops customized peptide-based vaccines targeting Alzheimer’s disease, Parkinson's disease, atherosclerosis, hypertension and other diseases with unmet medical needs.

11.31

AiVita Biomedical

06-Jun-2016

Irvine, CA

Early Stage VC The company helps to advance commercial and clinical stage programs utilizing curative and regenerative medicines.

2.01

AlBorj Laboratories

06-Jun-2016

Jeddah, Saudi Arabia

Alersense

24-Jun-2016

San Mateo, CA

Algaeon

07-Jun-2016

Indianapolis, IN

Allecra Therapeutics

15-Jun-2016

Delos Capital

13-Jun-2016

Early Stage VC Developer of novel antibiotics to combat Gram-negative bacterial infections. Early Stage VC The company is focused on developing novel protein‐based immunotherapies using its proprietary variant immunoglobulin domain (vIgD™) platform technology. It has also developed transmembrane immunomodulatory protein (TIP™) technology, based on vIgD™, for direct applications with engineered cellular therapies.

24.88

Alpine Immune Sciences

Weil am Rhein, Germany Seattle, WA

48.00

OrbiMed Advisors

Alzamend Neuro

22-Jun-2016

Salt Lake City, UT

Angel Developer of cell-based therapeutic vaccines as an immunotherapy to (individual) prevent or slow down Alzheimer's disease. Later Stage VC The company is involved in the development, commercialization and implementation of plasma technologies for the production and processing of nanomaterials.

Amastan Technologies 21-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

North Andover, MA

FCPB Affi, Santo Venture Capital, HMW Innovations

California Technology Ventures Undisclosed Investcorp, Jadwa PE Growth/ The company operates as a medical laboratory providing medical Expansion laboratory analysis for commercial and medical governmental hospitals, Investment, Swicorp clinics and pharmaceutical companies. Angel The company develops a device that delivers environmental readings on Undisclosed Undisclosed (individual) airborne contaminants and toxins, warning asthma and allergy sufferers as particles build. Early Stage VC The company produces astaxanthin, an antioxidant, and beta glucan, an 0.26 Undisclosed immunity-boosting supplement, for the human nutraceutical, functional foods and animal feed markets via a patented algae cultivation system.

Undisclosed Undisclosed 2.12

LaunchCapital

4

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Round

Description

Last Financing Size (Millions)

AnaBios

03-Jun-2016

San Diego, CA

Later Stage VC The company deploys assays and develops databases for the assessment 5.13 of ex-vivo human responses to drugs and the investigation of the molecular and functional basis of human physiology.

Analytics 4 Life

27-Jun-2016

Toronto, Canada

Angel (individual)

Ancera

28-Jun-2016

Branford, CT

Animated Dynamics

13-Jun-2016

Indianapolis, IN

Annexon Bioscience

23-Jun-2016

Antera Therapeutics

01-Jun-2016

South San Francisco, CA Allston, MA

Applied StemCell

06-Jun-2016

Milpitas, CA

Arkis Biosciences

24-Jun-2016

Knoxville, TN

Ashvattha Therapeutics Autonomic Technologies AVM Biotechnology

01-Jun-2016

Redwood City, CA Angel Developer of nano therapies for cerebral palsy. 0.04 (individual) Redwood City, CA Later Stage VC The company engages in the development and commercialization of 5.04 therapeutic devices for the treatment of severe headaches. Seattle, WA Later Stage VC Developer of stem cell technologies for regenerative medicine, oncology 2.74 and human biologics.

07-Jun-2016 09-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

Lead Investor(s)

Undisclosed

Provider of a cardiac monitoring device. The company uses advanced Undisclosed Undisclosed signal processing techniques for the purposes of identifying and assessing diseases in the coronary artery. 8.90 Glass Capital Early Stage VC The company's platform is for the separation, concentration and manipulation of various pathogens, cells and intracellular matter from whole blood or other complex background matrices. Early Stage VC The company develops a bio dynamic imaging technology that helps in 1.70 Caravel Ventures phenotype drug response mapping in tumor tissue of chemotherapy and detection of diverse cellular motions inside living tissue. Early Stage VC Developer of novel disease-modifying drugs to treat neurodegenerative disorders. Seed Round Provider of therapies that prevent allergy development in children and adults. Later Stage VC The company provides stem cell reagents and drug screening tests for gene-editing and stem cell innovation for research institutions and pharmaceutical companies. Early Stage VC The company provides surgical tools and implantables for advancing the treatments of intracranial hypertension arising from traumatic brain injury, hemorrhagic stroke, hydrocephalus, and similar disorders.

44.00

19.00

New Enterprise Associates RA Capital Management HerMed Capital

3.40

Innova Memphis

2.02

Undisclosed Undisclosed Undisclosed

5

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Round

Description

Last Financing Size (Millions)

Lead Investor(s)

Awarepoint

15-Jun-2016

San Diego, CA

Later Stage VC Provider of workflow automation and tracking applications to the acute 1.50 care hospital marketplace. The company provides a real-time location system for management and compliance regarding hospital assets.

Undisclosed

Axcella Health

07-Jun-2016

Cambridge, MA

Undisclosed

BBS-Bioactive Bone Substitutes Bergen Medical Products BioBots

23-Jun-2016

Oulu, Finland

16-Jun-2016

Cedar Knolls, NJ

07-Jun-2016

Philadelphia, PA

Later Stage VC The company's platform leverages advanced biotechnology tools, typically applied to drug development, that are applied to food to discover pharmacologically active protein nutrients. Later Stage VC Developer of osteopromotive bone substitute implants based on bone protein extract. Early Stage VC A medical device company targeting surgeries in the orthopedics and trauma in emergency departments. Early Stage VC The company helps scientists in building regenerative medicines and prototype of artificial 3-D tissues using photocurable materials.

BioPhotas

23-Jun-2016

Tustin, CA

Blade Therapeutics

08-Jun-2016

Bullet Biotechnology

28-Jun-2016

Cardia

30-Jun-2016

Eagan, MN

Cascade Prodrug

03-Jun-2016

Eugene, OR

Compiled by: Terence Yen Source: Pitchbook

112.00

Undisclosed Finnvera Venture Capital 0.67 Undisclosed 1.50

Angel (individual)

The company develops and sells a light energy medical device to treat 0.41 various musculoskeletal and skin conditions, including acne, wrinkles and pain. San Francisco, CA Early Stage VC Operator of a drug development company that provides antifibrotic 25.60 treatment strategies that address a variety of congenital and acquired diseases of fibrosis. Redwood City, CA Early Stage VC The company is developing a therapy to fight cancer by training the 0.34 body to trigger an immune response towards a particular identifier on an individual patient’s cancer cells, thereby eliminating these cells as threats. Angel (individual)

The company develops, manufactures and markets transcatheter septal 0.75 occluders with the intent to help people with congenital cardiac defects lead happy and healthy lives. Later Stage VC The company develops drug candidates which are prodrug derivatives of 0.35 vinca alkaloid compositions with promising activity for treating hyperproliferative disorders.

DreamIt Ventures

Undisclosed

Deerfield Management Undisclosed

Undisclosed

Undisclosed

6

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

Catacore

24-Jun-2016

Cell Design Labs

16-Jun-2016

Centrillion Technologies

10-Jun-2016

Cerium Pharmaceuticals

27-Jun-2016

Certa Dose

08-Jun-2016

CircleLink Health

14-Jun-2016

Clarify Health Solutions

09-Jun-2016

CoDa Therapeutics

13-Jun-2016

Common Sensing

16-Jun-2016

Cor (Wellness)

21-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

HQ Location

Round

Description

West Richland, WA Angel Provider of non-surgical treatment for cataracts. (individual) San Francisco, CA Early Stage VC The company develops disruptive cell-based therapies for cancer and other diseases. It leverages the power of the body’s immune system to develop therapies with the capability to treat diseases. Palo Alto, CA Later Stage VC The company is a developer and provider of genomic and bioinformatics tools and services that analyze technology for personalized medicine, life sciences research and bioinformatics. Gaithersburg, MD Angel Operator of a biopharmaceutical company for developing and (individual) commercializing medicines, namely orphan drugs, for rare and ultra-rare diseases. Denver, CO Seed Round The company helps in reducing and eliminating the errors in pediatric medicine dosing and provides certainty during emergencies and other life-altering situations. Stamford, CT Early Stage VC The company's technology provides a communication system for healthcare practitioners to monitor patients and intervene to ensure the patients adhere to their prescribed care plans. San Francisco, CA Angel Provider of a collaborative healthcare platform that enables patients and (individual) their families to understand the different steps of treatment and recovery. San Diego, CA Later Stage VC Developer of wound care and tissue repair therapeutics based on gap junction modulation. Cambridge, MA Early Stage VC The company offers a hardware- and software-based medical device that records a person's insulin intake information and transmits the data to mobile phones or glucose meters. San Francisco, CA Accelerator/ The company's device helps users track and maintain their fitness by Incubator measuring and providing them with insights from key health indicators like cholesterol, blood pressure and blood glucose.

Last Financing Size (Millions)

Lead Investor(s)

0.03

Undisclosed

22.89

Kleiner Perkins Caufield and Byers

27.10

Undisclosed

2.27

Undisclosed

0.55

Undisclosed

0.99

DreamIt Ventures

3.00

Undisclosed

0.75

Undisclosed

1.65

Undisclosed

Undisclosed MedTech Innovator

7

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Cordata Healthcare Innovations

Last Financing Date

HQ Location

13-Jun-2016

Cincinnati, OH

CRISPR Therapeutics 24-Jun-2016

Cambridge, MA

CrossRoads Extremity 02-Jun-2016 Systems Curavac

Round

Description

Last Financing Size (Millions)

Lead Investor(s)

Early Stage VC The company specializes in providing data driven insights, mobile screening programs and direct patient engagement by enabling patients to connect to hospitals and healthcare organizations for cost effective treatments. Early Stage VC Developer of transformative gene-based medicines for patients with serious diseases.

2.09

Undisclosed

140.00

Memphis, TN

Early Stage VC The company designs, manufactures and markets orthopedic medical and surgical devices for surgeons to restore function and alleviate pain.

2.19

Vertex Pharmaceuticals, Bayer Group MB Ventures

21-Jun-2016

Wilmington, DE

Angel (individual)

Undisclosed Undisclosed

CureJoy

14-Jun-2016

Burlingame, CA

CVRx

14-Jun-2016

Minneapolis, MN

CyMedica Orthopedics

09-Jun-2016

Scottsdale, AZ

DailyRounds

17-Jun-2016

Sunnyvale, CA

Diagenode

20-Jun-2016

Liege, Belgium

Compiled by: Terence Yen Source: Pitchbook

Developer of therapeutic vaccines to treat autoimmune diseases, such as sclerosis, diabetes, rheumatoid arthritis and systemic lupus erythematosus. Early Stage VC Developer of a platform to seek reliable information on alternative and natural healthcare from the experts in the field. Later Stage VC The company provides a proprietary implantable technology designed to trigger the body’s natural blood-flow regulation system to treat hypertension and heart failure. Early Stage VC The company creates orthopedic products designed to stabilize joints while providing neuromuscular electrical stimulation to keep muscles from weakening due to lack of use as the joint heals. Seed Round Developer of a case-based, problem-solving mobile platform for medical practitioners that enables doctors to see, share, review and learn clinical cases. Later Stage VC Manufacturer of diagnostic assays. The company develops and sells epigenetic tools for life-science research market, as well as products designed to make diagnostic assays simpler and faster.

4.40

Accel Partners

46.51

Undisclosed

5.64

Undisclosed

1.20

Undisclosed

8.48

Societe Regionale d'Investissement de Wallonie, Epimede, Ostbelgieninvest, Capricorn Venture Partners

8

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

EarLens

15-Jun-2016

Menlo Park, CA

EarlySense

01-Jun-2016

Ramat Gan, Israel

Eccrine Systems

28-Jun-2016

Cincinnati, OH

Echo Labs

21-Jun-2016

Palo Alto, CA

Ecolight (Italy)

22-Jun-2016

Lecce, Italy

Element Diagnostics

13-Jun-2016

Eleusis Benefit Corporation Emerge Diagnostics

27-Jun-2016 23-Jun-2016

Entegrion

03-Jun-2016

ePatientFinder

09-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

Round

Description

Later Stage VC The company develops an open-canal hearing device for transmitting sound to the ear. Later Stage VC The company's technology provides continuous patient monitoring for heart rate, respiratory rate and motion to potentially allow the clinical team to manage early detection of patient deterioration.

Last Financing Size (Millions)

Lead Investor(s)

53.59

Vertex Healthcare

25.00

Bank Hapoalim

Early Stage VC Developer of sweat sensor technologies. The company is developing 4.56 Undisclosed small disposable electronic patches that use sensors to measure different chemicals present in sweat. Accelerator/ The company's patent-pending wearable technology allows for Undisclosed MedTech Innovator Incubator noninvasive monitoring and analysis of blood composition. It also tracks key physiological indicators of energy, fitness, nutrition, hydration and sleep, without the need for traditional blood testing.

Early Stage VC Developer of a medical device for diagnosis of osteoporosis. The company provides a echo-graphic system to measure the bone strength at spine and femur level. Charlottesville, VA Angel Developer of a cancer diagnostic system. (individual) New York, NY Angel Developer of restricted small molecule drugs to address critical unmet (individual) needs. Carlsbad, CA Angel The company has developed an FDA-registered, class-II diagnostic (individual) device called an Electrodiagnostic Functional Assessment (EFA) that can age and evaluate muscle activity, distinguish between acute versus chronic injury and objectively quantify effort. Durham, NJ Later Stage VC The company develops pharmaceutical agents that address unmet needs in military healthcare involving wound management, tissue repair and hemorrhage control. Austin, TX Angel The company's software uses analytics technology for identifying (individual) patients that are ideal candidates for preventative procedures and clinical trial opportunities.

4.52

Panakes Partners, Invitalia Ventures

0.38

Undisclosed

0.98

Undisclosed

1.85

Undisclosed

3.33

Undisclosed

8.20

Undisclosed

9

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

Ermes Medical Company Evidation Health

17-Jun-2016

F2G

20-Jun-2016

Factory-CRO

01-Jun-2016

FlowMetric

29-Jun-2016

Flowonix Medical

HQ Location

Round

Description

Last Financing Size (Millions)

Angel Developer of metal chelator and antioxidants. 3.59 (individual) San Mateo, CA Early Stage VC The company helps its partners quantify and optimize health outcomes 11.60 through advanced analytics of medical, behavioral and contextual data at the patient-consumer level. Manchester, United Later Stage VC Developer of drugs to treat life threatening fungal disease. 60.00 Kingdom Bilthoven, PE Growth/ Provider of contract research services to the healthcare sector. The Undisclosed Netherlands Expansion company specializes in the management of clinical studies for medical devices, biologicals and device drug combinations. Doylestown, PA Angel The company offers flow cytometry techniques that combine proprietary 0.93 (individual) assays with advanced analytics to support all stages of drug development including pre-clinical, non-clinical and clinical development.

Undisclosed

01-Jun-2016

Mount Olive, NJ

15.50

Clarus Ventures

Fog Pharmaceuticals

07-Jun-2016

Boston, MA

7.43

Undisclosed

Forest Devices

06-Jun-2016

Pittsburgh, PA

0.16

Undisclosed

37.75

Syncona Partners, University College London (UCL)

5.55

Andreessen Horowitz

2.82

Undisclosed

02-Jun-2016

Dublin, Ireland

Lead Investor(s)

Later Stage VC Developer of implantable devices to deliver therapeutic drugs into the spine for management of chronic pain. Angel The company develops medicines that use cell-penetrating miniproteins (individual) to access validated intracellular disease drivers and for honing of therapeutically beneficial tissues. Angel Developer of a medical device to detect ischemic and hemorrhagic (individual) stroke before the patient is taken to the hospital. Early Stage VC The company is focused on the development and commercialization of gene therapies for bleeding and other debilitating disorders based on a next-generation AAV (Adeno-associated virus) gene therapy platform.

Freeline Therapeutics 20-Jun-2016

London, United Kingdom

Freenome

07-Jun-2016

Philadelphia, PA

Seed Round

Fresenius Medical Care Youngstown

16-Jun-2016

Waltham, MA

Angel (individual)

Compiled by: Terence Yen Source: Pitchbook

The company develops proprietary algorithms and methods and offers technology services to enable and empower diagnosis of clinical conditions. Provider of healthcare services for renal and kidney patients. The company specializes in providing kidney dialysis services and manufacturing renal care products.

B Capital Group

Sectoral Asset Management Kester Capital

Undisclosed

10

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Round

Description

Fruit Street Health

01-Jun-2016

Richmond, CA

Garwood Medical Devices

02-Jun-2016

Buffalo, NY

Genetesis

13-Jun-2016

Mason, OH

Angel (individual)

GEROPHARM

17-Jun-2016

Ginkgo Bioworks

08-Jun-2016

St. Petersburg, Russia Boston, MA

PE Growth/ Developer of pharmaceutical drugs, ingredients and other related Expansion products. Later Stage VC Provider of biological engineering services. The company provides biology technologies to design, build and test new organisms across a range of industries from fuels to pharmaceutical production.

Guardion Health Sciences

07-Jun-2016

San Diego, CA

Angel (individual)

Guoke Hengtai Medical Technology HealthPrize Technologies

21-Jun-2016

Beijing, China

24-Jun-2016

Norwalk, CT

Later Stage VC The company's customizable platform combines incentives, behavioral economics and education to track medication compliance and rewards consumers for following their prescriptions.

HemoGenyx

29-Jun-2016

Buffalo, NY

Seed Round

Hexislab

06-Jun-2016

Newcastle upon Tyne, United Kingdom

Compiled by: Terence Yen Source: Pitchbook

Last Financing Size (Millions)

Early Stage VC The company's software allows healthcare providers to monitor lifestyle 5.40 and behavioral health by connecting with patients using telemedicine and wearable mobile technologies. Angel The company develops medical devices to treat implant infections, 2.05 (individual) stimulate bone growth and aid wound healing using electro stimulation. Developer of a cardiac current density mapping technology. The company's technology reconstructs the areas of high and low electrical conductivity in the heart by using the body’s weak magnetic fields.

The company manufactures nutritional supplements that help restore and replenish the macular protective pigment to address age-related macular degeneration. Early Stage VC Distributer of medical devices.

0.35

Lead Investor(s)

Undisclosed

Undisclosed

Undisclosed

Undisclosed Russian Direct Investment Fund 100.00 Baillie Gifford, Viking Global Investors, Allen & Company 0.08 Undisclosed

1.53 2.85

The company leverages AHE cells which generate cancer-free blood 1.00 stem cells to treat blood cancer and also increase the efficacy of bone marrow transplants and eliminate the need for donors. Early Stage VC The company provides skin-care research and development consultancy 0.17 services using computer modeling to identify natural active compounds for skin care and nutrition.

CASH Capital, Legend Capital Mansa Capital, Robert Dahl, Trygve Mikkelsen Undisclosed

Northstar Ventures

11

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Hi.Q

06-Jun-2016

Hinge Health

20-Jun-2016

HistoWiz

07-Jun-2016

Brooklyn, NY

Hospital IQ

17-Jun-2016

Newton, MA

IFM Therapeutics

22-Jun-2016

Cambridge, MA

Iggbo

21-Jun-2016

Richmond, VA

ImagenTechnologies

21-Jun-2016

New York, NY

IMCS Group

02-Jun-2016

West Palm Beach, FL

Compiled by: Terence Yen Source: Pitchbook

Round

Description

Mountain View, CA Early Stage VC Developer of a health knowledge measurement application. The company's application functions like a game with players completing quizzes and competing against others for mastery of nutrition, exercise and medical conditions. San Francisco, CA Angel Provider of healthcare facilities for musculoskeletal disorders. The (individual) company offers healthcare facilities with the help of sensor technology for musculoskeletal disorders and offers a digital health program.

Last Financing Size (Millions)

Lead Investor(s)

4.00

Undisclosed

1.33

Undisclosed

Accelerator/ Incubator

The company provides histopathology services that include processing, 0.34 cutting, staining mouse tissue samples and digitizing the results for cancer researchers in academia and pharma. Early Stage VC The company offers an online platform that enables doctors to schedule 6.25 their surgeries, collaborate with patients and optimize resource utilization in hospitals. It provides automated reporting, modeling and prediction tools for hospitals or hospital networks. Early Stage VC Developer of small molecule drugs for the treatment of life threatening 27.00 diseases. The company discovers and develops small molecules that modulate novel targets in the innate immune system for treating cancer, autoimmunity and inflammatory disorders.

Early Stage VC The company connects independent laboratories, physicians and 13.00 phlebotomists via a mobile application and manages every aspect of diagnostic testing including the initial requisition to packing and shipping of samples. Angel Developer of a medical imaging technology. The company uses 5.00 (individual) computer vision and machine learning to offer medical imaging which is free of diagnostic errors. Angel The company provides bio-psychophysical and bio-psychosocial 1.00 (individual) assessments to assist patients, employers, workers’ compensation and disability organizations with services for chronic pain and disability claims.

Y Combinator

Undisclosed

Atlas Venture, Abingworth Management

Heritage Groupon

Undisclosed

Undisclosed

12

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

Immutrix Therapeutics

28-Jun-2016

ImStar Therapeutics

12-Jun-2016

InFlectis BioScience

01-Jun-2016

Intensity Therapeutics 28-Jun-2016

Intensix

09-Jun-2016

HQ Location

Rapid City, SD

Round

Description

The company develops medical products which seek to remove inflammatory mediators and toxins from patient's blood in order to alter the therapeutic outcomes of treatments. Vancouver, Canada Seed Round The company researches, discovers, develops and commercializes therapeutics for the treatment of amyotrophic lateral sclerosis. It may also benefit other neurodegenerative conditions such as Alzheimer's, Parkinson's disease and dementia. Nantes, France Early Stage VC Developer of small molecule drugs. The company develops small molecule drugs for the treatment of misfolding protein disorders such as neurodegenerative and age-related diseases. Westport, CT Early Stage VC Provider of chemotherapy treatments for cancer patients. The company has developed chemotherapy drugs that can be used for the primary tumor and major visible metastases. Netanya, Israel

Angel (individual)

Undisclosed

1.39

Accel-Rx, Business Development Bank of Canada

6.79

CM-CIC Capital Innovation, Remiges Ventures FastForward Innovations, Batterson Venture Capital, Vcapital 8200 EISP

10.00

The company's platform delivers predictive clinical analytics that provide 0.01 hospital management and medical personnel with the information they require to manage the intensive critical care floor. Later Stage VC The company develops synthetic polymers for cancer treatment. It is 20.00 developing multi-modal oncology compounds that combine tissue, cellular and molecular targeting with tumor-specific release mechanisms.

Tampa, FL

InTouch Health

15-Jun-2016

Santa Barbara, CA

Later Stage VC Provider of virtual clinical care services.

Invenios

22-Jun-2016

Santa Barbara, CA

Invisalert Solutions

22-Jun-2016

Warminster, PA

Angel (individual) Angel (individual)

IsoPlexis

29-Jun-2016

Branford, CT

Lead Investor(s)

2.93

Accelerator/ Incubator

Intezyne Technologies 20-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

Last Financing Size (Millions)

Undisclosed

15.00

Undisclosed

The company specializes in designing, developing and manufacturing 10.00 microfluidics, MEMS, and 3D microstructures. The company offers a platform technology that uses mobile software 1.00 tools to solve problems in acute healthcare, corrections, drug delivery and long-term care. Early Stage VC The company's single cell multiplexing immunoassay and software suite 5.75 provides in-depth biological characterization of immune and cancer cell subsets among heterogeneous populations.

Undisclosed Undisclosed

Connecticut Innovations

13

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Jiff

07-Jun-2016

Kickstart (Neurorehabilitation Device) KiDi SMS

09-Jun-2016

Kit Check

20-Jun-2016

Liquid Genomics

27-Jun-2016

LivOnyx

27-Jun-2016

Madorra

21-Jun-2016

Maven

03-Jun-2016

MaveriX Oncology

02-Jun-2016

Palo Alto, CA

Medella Health

03-Jun-2016

Waterloo, Canada

Medical Simulation

14-Jun-2016

Centennial, CO

03-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

Round

Description

Mountain View, CA Later Stage VC The company offers JiffPad, a tool that enables users to capture voice, teaching materials, gestures, patients' questions and replies. Seattle, WA Later Stage VC The company offers Kickstart Walking System, a neurorehabilitation system to retrain walking following stroke, incomplete spinal cord injury and related neurological conditions. Oakville, Canada Accelerator/ Provider of an online diabetes self-management system for kids. The Incubator company offers an interactive, online gaming platform for selfmanagement of blood glucose for children with Type 1 diabetes. Washington, DC Later Stage VC Provider of a platform for tracking hospital pharmacy kits and medications. Torrance, CA Angel Operator of a blood-based biomarker company. The company is (individual) focused on monitoring cancer patients for chemotherapy response using non-invasive, blood-based molecular testing methods. Allston, MA Angel Provider of a hand disinfection system to reduce healthcare associated (individual) infections. Mountain View, CA Accelerator/ The company develops a non-hormonal, medical device treatment for Incubator vaginal dryness and atrophy caused by cancer treatment. New York, NY Seed Round The company provides a healthcare application for booking appointments through a network of nurse practitioners, gynecologists, mental health specialists, physical therapists and nutritionists. Angel (individual) Seed Round

Developer of drugs for cancer therapeutics.

Last Financing Size (Millions)

Lead Investor(s)

41.15

Rosemark Capital

0.10

Undisclosed

Undisclosed The Forge

15.00

Baxter Ventures

0.08

Undisclosed

0.49

Undisclosed

Undisclosed MedTech Innovator Undisclosed Undisclosed

1.00

Undisclosed

The company develops smart contact lenses that continuously and non- 1.40 invasively monitor glucose levels and transmit that information to a mobile phone. Later Stage VC Provider of simulation training, education and consulting services to 1.23 hospital personnel, medical product manufacturers and medical societies.

Hedgewood

Undisclosed

14

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Medi-Tate

29-Jun-2016

Or Akiva, Israel

MedWand Solutions

06-Jun-2016

Las Vegas, NV

Round

Description

Last Financing Size (Millions)

Later Stage VC The company provides new methods for treating diseases of the urethra 4.00 Xenia Venture and prostate, with a focus on reducing associated symptoms and Capital improving patients' quality of life. Seed Round The company develops a device that serves as a portable physical health Undisclosed Foxlink Group examiner which is done through a secure internet connection.

Mersana Therapeutics 24-Jun-2016

Cambridge, MA

Later Stage VC Developer of biodegradable and bio inert material for drug protection. The company's products conjugate for the treatment of multiple tumor types and various preclinical oncology compounds.

33.10

Metabolomic Diagnostics

16-Jun-2016

Cork, Ireland

2.00

Metamason

01-Jan-2016

Los Angeles, CA

Metritrack

23-Jun-2016

Hillside, IL

Milo Biotechnology

02-Jun-2016

Cleveland, OH

Mips

16-Jun-2016

Seattle, WA

Early Stage VC The company provides an early pregnancy test to identify a woman's risk of developing pre-eclampsia later in her pregnancy through the use of metabolomic profiling. Angel Developer of a 3D based respiratory device. The company provides a (individual) continuous positive airway pressure (CPAP) mask for breathing to overcome sleep apnea. Angel Developer of a hand-held ultrasound device which helps in the diagnosis (individual) of breast cancer. Early Stage VC Developer of gene therapies for muscular dystrophy. The company's therapy is based on a protein called follistatin that stimulates muscle growth and prevents muscle scarring after injury. Angel The company specializes in collecting adult cells, processing and growing (individual) the cells, cryopreserving them to prevent aging and also converting a small percentage of them into induced pluripotent stem cells.

Mirabilis Medica

01-Jun-2016

Bothell, WA

Mironid

20-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

Lead Investor(s)

Wellington Management Company

SOSV, Enterprise Equity, Enterprise Ireland Undisclosed Tsing Capital, 3P Equity Partners 0.10

Undisclosed

0.40

Undisclosed

0.09

Undisclosed

Later Stage VC The company is in clinical development of a non-invasive therapeutic 5.15 ultrasound platform with an initial application to the treatment of uterine fibroids. Newhouse, United Early Stage VC Developer of therapeutics for the treatment of kidney diseases, chronic 6.24 Kingdom inflammatory diseases and cancer.

Undisclosed

Epidarex Capital

15

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Morphic Therapeutic 30-Jun-2016

Waltham, MA

Myocardial Solutions

01-Jun-2016

Morrisville, NC

Myspiroo

29-Jun-2016

NaturalCycles

22-Jun-2016

Neolight

15-Jun-2016

NeuroVision Imaging 29-Jun-2016

Neusoft Medical Systems

27-Jun-2016

NeuSpera Medical

13-Jun-2016

Newronika

14-Jun-2016

NeXtGen Biologics

13-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

Round

Description

Early Stage VC Developer of oral integrin therapies for patients with immunological, fibrotic, neoplastic and vascular diseases.

Later Stage VC Developer of magnetic resonance image analysis software. The company provides healthcare software analysis tools focused on supporting the cardiovascular field. Warsaw, Poland Seed Round The company has developed a spirometer device that helps to control asthma and reduce the number of exacerbations. Stockholm, Sweden Early Stage VC The company's application allows women to see which days of the month they are fertile. The platform also includes tools for analyzing ovulation test results. Scottsdale, AZ Angel Developer of phototherapy beds to cure jaundice in pre-term and full(individual) term babies. Sacramento, CA Later Stage VC The company develops digital imaging, diagnostic tests, and biomarkers for early detection and monitoring of amyloid pathology related to Alzheimer’s Disease and eye care. Shenyang, China PE Growth/ The company provides digital medical imaging equipment including CT, Expansion MRI, X-ray, Ultrasound, PET (Positron Emission Tomography), Linear Accelerator, IVD (In Vitro Diagnostic Products) and other e-hospital software. Santa Clara, CA Angel The company develops implantable neuromodulation devices using mid(individual) field powering techniques to improve the lives of patients suffering from chronic illness. Milan, Italy Early Stage VC The company has developed a patented technology to stimulate Deep Brain Stimulation (DBS) to treat patients affected by Parkinson’s disease, record brain activity and modulate neurostimolation. Gainesville, FL

Angel (individual)

Last Financing Size (Millions)

51.50

4.02

1.10 6.09

Lead Investor(s)

SR One, Pfizer Venture Investments Undisclosed

Joint Polish Investment Fund Bonnier Growth Media

0.78

Undisclosed

10.00

Wildcat Capital Management

Undisclosed China Everbright

8.88

Undisclosed

1.92

Innogest

Manufacturer of ECM biomaterial products. The company provides Undisclosed Undisclosed optimized clinical benefits and focuses on neurosurgery and orthopedics.

16

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Nortis

29-Jun-2016

Seattle, WA

NovellusDx

22-Jun-2016

Jerusalem, Israel

Nuviant Medical

16-Jun-2016

Dallas, TX

Omicia

08-Jun-2016

Operative Experience 27-Jun-2016

OptiScan Biomedical 07-Jun-2016 Otolith Sound

21-Jun-2016

Owlstone Medical

28-Jun-2016

PeptiMed

10-Jun-2016

PhysioWave

24-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

Round

Description

Last Financing Size (Millions)

Lead Investor(s)

Angel (individual)

The company develops a technology that allows in-vitro creation of Undisclosed Undisclosed human tissues and organs in disposable chip-like devices helping accelerate research and advance scientific exploration. Early Stage VC The company offers a technology that helps in comprehensive, 12.50 InterCure automated, functional gene profiling of individual patient cancer tumors to aid oncologists in selecting the right therapy for each patient.

Angel The company develops implantable therapies for the relief of chronic Undisclosed (individual) conditions. Oakland, CA Later Stage VC The company focuses on the interpretation of genome sequences for 23.00 clinical applications by powering informatics approaches that power nextgen sequencing applications for clinical testing, translational research and drug development. North East, MD Angel Developer of a simulation-based surgery training system. The company 1.00 (individual) develops a system for surgery and EMS training which includes life-like patient models and surgical simulators. Hayward, CA Later Stage VC Provider of instruments and sensors for automated measurement of 29.47 blood glucose levels. Washington, DC Angel The company develops a wearable headset that allows users to ignore 0.03 (individual) undesired sensory information from their vestibular system, thereby helping them to get rid of motion sickness. Cambridge, United Angel Owner and operator of a medical diagnostics company. The company 7.26 Kingdom (individual) offers clinical trial services and also offers a lonestar gas analyzer, ultrafaims and related products. Madison, WI Early Stage VC The company engages in research and development of nano-particle 0.50 delivery systems and therapeutic drugs that help in permanent remission of cancer. Santa Clara, CA Angel Developer of medical devices. 6.64 (individual)

Undisclosed UPMC Enterprises, Roche Venture Fund, LDV Partners Undisclosed

Undisclosed Undisclosed

Medtekwiz Advisory

Undisclosed

Undisclosed

17

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Round

Pillars4Life

15-Jun-2016

Los Angeles, CA

Angel (individual)

PNP Therapeutics

15-Jun-2016

Birmingham, AL

Later Stage VC

Preceptis Medical

24-Jun-2016

Plymouth, MN

Early Stage VC

PreDxion Bio

21-Jun-2016

Ann Arbor, MI

Accelerator/ Incubator

Premia Spine

08-Jun-2016

Herzeila, Israel

Later Stage VC

Presbyopia Therapies 29-Jun-2016

Coronado, CA

Angel (individual)

Prescriber's Choice

28-Jun-2016

Pompano Beach, FL

Angel (individual)

Primex Pharmaceuticals

23-Jun-2016

Helsinki, Finland

Later Stage VC

Procured Health

14-Jun-2016

Chicago, IL

Early Stage VC

ReActive Robotics

02-Jun-2016

Gilching, Germany Early Stage VC

Compiled by: Terence Yen Source: Pitchbook

Description

The company offers a social platform where cancer patients are offered resiliency curriculum and distance learning technology to help them overcome their social and emotional challenges. The company engages in research and development of proprietary products and technology for cancer treatment. Manufacturer and developer of medical devices and surgical tools. The company's products allow children's ear tube procedures to be performed without the use of general anesthesia. The company develops a diagnostic device that enables doctors to measure certain proteins like cytokines in the blood of critically-ill patients. The company offers a mechanical device that is housed between two titanium plates, which allows axial rotation, lateral bending, extension and flexion during spinal surgery. Developer of a vision enhancing eye drop. The company develops an eye drop combining miotic agent aceclidine and cyclopegic tropicamide to temporarily correct presbyopia for up to six hours. The company offers a Web-based platform to assist physicians with their patients by improving patient education, compliance, and ultimately enhanced outcomes. The company specializes in the production and supply of medicines and healthcare products in the fields of cardiology, anesthesia, oncology and intensive care. The company provides a platform designed to enable hospital administrators to automate and analyze product evaluation processes and procurements. The company provides rehabilitation robots that automate gait rehabilitation at a very early stage, 48 hours post-stroke in the ICU.

Last Financing Size (Millions)

Lead Investor(s)

0.30

Undisclosed

0.34

Undisclosed

0.09

Undisclosed

Undisclosed MedTech Innovator

15.00

Undisclosed

3.40

Undisclosed

0.71

Undisclosed

Undisclosed Finnvera Venture Capital 10.00

Heritage Group

Undisclosed Lead MTIP MedTech Innovation Partners

18

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Round

Description

Last Financing Size (Millions)

Lead Investor(s)

Recor Medical

08-Jun-2016

Palo Alto, CA

Later Stage VC Developer of an investigational device that provides a transcatheter 10.00 treatment for mitral valve insufficiency (regurgitation). The company has also devised a therapeutic ultrasound system for performing renal denervation in patients with resistant hypertension.

Undisclosed

Recovery Force

23-Jun-2016

Fishers, IN

Undisclosed

Reflexion Health

22-Jun-2016

San Diego, CA

Angel The company develops wearable technology suits for athletes and sports 0.50 (individual) persons that help them to improve their performance. Early Stage VC Developer of a prescription software for physical therapy. The company 18.00 offers a rehabilitation medicine tool built on Microsoft's Kinect for Windows to track patient adherence for the prescribed rehab plan.

Relevium Labs

17-Jun-2016

Oxford, OH

Angel (individual)

Remedy

17-Jun-2016

San Francisco, CA

Accelerator/ Incubator

RetraceHealth

07-Jun-2016

Minneapolis, MN

Rgenix

15-Jun-2016

New York, NY

Early Stage VC Provider of an online platform that connects patients to medical 6.53 providers. The company's services include preventive care, pediatric care and diagnostic testing. Early Stage VC Developer of cancer therapies that specifically target cancer metastasis. 33.00

Rodo Medical

21-Jun-2016

San Jose, CA

Root Lines Technology

03-Jun-2016

Amiens, France

Compiled by: Terence Yen Source: Pitchbook

Developer of a medical device for female urinary incontinence. The 0.40 company provides a non-narcotic, non-surgical device for treating and maintaining urinary control. 0.25 The company offers an online software that intercepts medical bills, resolves any errors, and overcharges directly with the providers. It also provides advice related to any medical ailment from specialists and helps its users to pay the correct balance online.

Later Stage VC The company provides a retention device, the RODO Abutment 0.57 System, that makes restorations on dental implants. It improves treatment outcomes by eliminating cement related complications and hassles associated with screw retention. PE Growth/ The company develops a pathogens-free plant root-based expression 2.26 Expansion system to secrete complex recombinant proteins useful for the treatment of rare diseases such as lysosomal diseases.

West Health Investments

Undisclosed

Financial Services Innovation

Lemhi Ventures

Novo, Sofinnova Partners Undisclosed

Picardie Investissement

19

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

RTM Diagnostika

20-Jun-2016

Moskva, Russia

RubiconMD

01-Jun-2016

New York, NY

Ryboquin

02-Jun-2016

Selkirk, United Kingdom

Sensoria

17-Jun-2016

Redmond, WA

SI-BONE

17-Jun-2016

San Jose, CA

Sipai Wangluo

03-Jun-2016

Beijing, China

Smart Med Reminder 07-Jun-2016

Sofie Biosciences

13-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

Round

Description

Last Financing Size (Millions)

Lead Investor(s)

Early Stage VC The company develops and manufactures devices for the diagnosis of 0.24 breast cancer. Early Stage VC The company provides specialty e-consults for clinicians through its web- 4.00 based and mobile platform that redesigns the referral process by bringing appropriate specialty expertise into the primary care setting.

Moscow Seed Fund, Biofond Waterline Ventures

Early Stage VC The company develops and commercializes oncology therapies, including ECP-102, a tumor apoptosis enhancer drug designed to optimize chemotherapy. Angel The company develops textile sensory devices, electronic (individual) instrumentation systems and software that targets fitness and health scenarios. Its products include sport bras, socks and T-shirts that deliver users' health data to mobile devices. Later Stage VC The company develops minimally invasive surgical devices for fracture fixation of long bones and large bone fragments of the pelvis for conditions including sacroiliac joint disruptions and degenerative sacroiliitis. Early Stage VC Provider of an oncology-focused big data platform. The company's platform aggregates oncology data from different hospitals to provide insight to doctors on various treatments.

0.01

TRI Cap, Braveheart, Strathtay Ventures Kickstarter

20.00

Arboretum Ventures

14.52

Undisclosed Eight Roads, FPrime Capital Partners, Ping An Ventures 1.50 Undisclosed

West Lafayette, IN Later Stage VC The company offers a monitoring system in the form of a medicine bottle cap, which tracks and reminds users to take medicines on time. The system stores the monitoring data wirelessly to a private online database. Culver City, CA Later Stage VC The company focuses on the development of positon emission 3.70 tomography (PET) imaging probes combined with imaging systems and chemistry platforms to help scientists and physicians investigate the biology of disease.

Undisclosed

20

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Solera (Health Network)

17-Jun-2016

Phoenix, AZ

Spinal Balance

03-Jun-2016

Toledo, OH

Spirometrix

30-Jun-2016

Pleasanton, CA

Spring Rain Software

23-Jun-2016

Beijing, China

Stage I Diagnostics

08-Jun-2016

Little Rock, AR

Stemina

06-Jun-2016

Storm Therapeutics

28-Jun-2016

Strata Oncology

02-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

Round

Description

Early Stage VC The company provides a proprietary SaaS platform that supports an integrated national network of community organization and digital providers of chronic disease prevention programs. Angel Developer of orthopaedic medical devices. The company develops (individual) spinal implants for the treatment of degenerative disease and deformity of the spine. Later Stage VC The company focuses on research, development and commercialization of breath analysis devices for application in disease diagnosis and management. Later Stage VC The company enables users to refer potential diseases by looking up symptoms or asking professional doctors free of charge through their online platform and healthcare application.

Last Financing Size (Millions)

4.00

Sandbox Industries, SJF Ventures

0.50

Undisclosed

17.40

Shanghai Fosun Pharmaceutical

183.00

China International Capital Corporation

The company develops products to provide a panel of markers to 0.10 diagnose early stage disease as well as offer opportunities for therapeutic intervention in cancer patients. Madison, WI Later Stage VC The company works on collaborative research projects and joint 1.00 development agreements with strategic partners to develop drugs, identify targets and discover molecular biomarkers for the diagnosis of diseases and customized treatment. Cambridge, United Early Stage VC Developer of small molecule drugs that target RNA-modifying enzymes 17.42 Kingdom for cancer treatment.

Ann Arbor, MI

Angel (individual)

Early Stage VC Owner and operator of a healthcare and precision medicine company.

Lead Investor(s)

12.00

Undisclosed

Undisclosed

Cambridge Innovation Capital, Imperial Innovations, Pfizer Venture Investments Arboretum Ventures, Baird Capital

21

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Suneva Medical

14-Jun-2016

San Diego, CA

SymbioCellTech

30-Jun-2016

Salt Lake City, UT

Tawada Healthcare

30-Jun-2016

Jakarta, Indonesia

Taxis Pharmaceuticals 15-Jun-2016

TeraPore Technologies

30-Jun-2016

Tevosol

29-Jun-2016

The Medical Memory 10-Jun-2016

Monmouth Junction, NJ

Description

PE Growth/ Expansion

The company is in the business of development, manufacturing and 25.00 commercialization of injectable aesthetic products for the dermatology and plastic surgery markets. Later Stage VC Developer of cell-based therapies for diabetes and other disorders. The 1.91 company offers an adult stem cell-based therapy for the cure of insulindependent Type I diabetes Mellitus. PE Growth/ Distributor of equipment such as x-ray machines, ultrasound machines, Undisclosed Expansion laboratory equipment, orthopaedic instruments and laparoscopy towers.

Developer and marketer of antibiotic and antiviral drugs. The company's drugs help to treat bacterial and viral infections and reduce the threat of antimicrobial resistance. South San Angel The company specializes in the manufacturing of filters for protein Francisco, CA (individual) separations and membrane separations for purification of biological fluids. Edmonton, Canada Angel The company offers organ transplant services in Edmonton that (individual) maintain critical organs such as hearts and lungs viable for transplant donors. Phoenix, AZ Later Stage VC The company offers a recording system to record patient-doctor interaction that can be uploaded to the cloud and shared with others.

Theraworx

06-Jun-2016

Asheville, NC

Thetis Pharmaceuticals

27-Jun-2016

Southport, CT

Third Pole

06-Jun-2016

San Francisco, CA

Compiled by: Terence Yen Source: Pitchbook

Round

Last Financing Size (Millions)

Angel (individual)

Lead Investor(s)

Essex Woodland

Undisclosed

Navis Capital Partners

3.03

Undisclosed

1.76

Undisclosed

2.00

Undisclosed

0.65

Undisclosed

Later Stage VC Provider of therapeutic skin care products. The company manufactures 10.09 products that include specialty care packs for peri-care prior to foley catheter insertion and on-going foley maintenance. Early Stage VC The company is focused on Type 2 diabetes and is working to advance 3.33 its TP101, which is a new molecular entity that chemically combines metformin with the principal component from omega-3 polyunsaturated fatty acids. Angel Developer of a medical inhalation device offering nitric oxide needed for 5.69 (individual) new born with respiratory failure.

Undisclosed

Connecticut Innovations

Undisclosed

22

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Round

Description

Last Financing Size (Millions)

Lead Investor(s)

Tonic

14-Jun-2016

Menlo Park, CA

Early Stage VC The company provides software for clinicians and researchers to create, 6.41 edit and manage surveys and questionnaires for patient screening, academic research studies, clinical trials and risk assessments.

Undisclosed

TowerView Health

22-Jun-2016

Philadelphia, PA

DreamIt Ventures

Traverse Biosciences

06-Jun-2016

Stony Brook, NY

TwinStrand Biosciences

24-Jun-2016

Bellevue, WA

Early Stage VC The company develops software and hardware that reminds patients and 0.70 their clinicians about medication schedules, and warns them when a patient is falling off track. Seed Round Developer of drug candidates to treat inflammatory diseases and related 0.50 conditions affecting humans and animals. Angel Developer of a DNA sequencing system. The company specializes in 1.94 (individual) deigning and developing a duplex sequencing system that eliminates false mutations by separately sequencing the two DNA strands.

Tyromotion

23-Jun-2016

Graz, Austria

PE Growth/ Expansion

UVision

07-Jun-2016

Durham, NC

Vactech

23-Jun-2016

Tampere, Finland

Angel (individual) Later Stage VC The company develops vaccines for microbes for underlying human diseases. Its therapy include Type 1 diabetes, asthma and allergies.

Valify

06-Jun-2016

Frisco, TX

VantagePoint Laboratory

24-Jun-2016

San Diego, CA

Compiled by: Terence Yen Source: Pitchbook

Excell Partners Undisclosed

The company specializes in the production and distribution of robotUndisclosed SHS Gesellschaft assisted and computer-assisted therapy units for the rehabilitation sector. fur Beteiligungsmanage ment Developer of a hysteroscopy office-based system. 0.11 Undisclosed Undisclosed Finnvera Venture Capital

Early Stage VC The company allows healthcare organizations to identify, benchmark and 2.08 track savings in purchased services, mitigate financial risk and manage the overall cost of operations. PE Growth/ The company provides esoteric testing services, such as molecular 7.88 Expansion testing, solid tumor testing, technical and professional component testing, cytogenic, FISH testing and hematopathology testing services.

Frist Cressey Ventures, Step 5 Capital Undisclosed

23

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Round

Description

Vedanta Biosciences

06-Jun-2016

Cambridge, MA

Later Stage VC The company develops a novel class of therapies that modulate pathways of interaction between the human microbiome and the host immune system.

Venus Medtech

01-Jun-2016

Hangzhou, China

PE Growth/ Expansion

Verax Biomedical

27-Jun-2016

Marlborough, MA

Vidac Pharma

29-Jun-2016

Jerusalem, Israel

Vii Network

02-Jun-2016

Washington, DC

Vios Medical

09-Jun-2016

Woodbury, MN

VirTech Bio

22-Jun-2016

Beverly, MA

VisCardia

07-Jun-2016

Beaverton, OR

Vitaeris

07-Jun-2016

Vancouver, Canada Seed Round

Compiled by: Terence Yen Source: Pitchbook

Last Financing Size (Millions)

50.00

Lead Investor(s)

Rock Springs Capital, Invesco Asset Management, Seventure

The company engages in research, development and industrialization of 40.00 cardiovascular medical devices, which includes artificial aortic valves, percutaneous devices, conveyor systems and other heart treatment related devices. Later Stage VC The company provides the Platelet PGD Test, a rapid test for the 12.61 detection of bacterial contamination in platelets. Its products have applications for use in blood banks as well as entities engaged in blood transfusions and transplants. Early Stage VC The company develops anti-cancer medicines for oncologic and 9.00 dermatologic diseases. Angel Developer of an interactive web platform. The company offers Platform- 4.95 (individual) as-a-Service (PaaS) infrastructure focused on healthcare applications at the health system level. Angel The company's platform offers a wireless monitoring system to patients, 3.98 (individual) clinicians and hospitals for providing access to healthcare through new care models. Angel The company uses a technology platform that combines machine 0.50 (individual) perfusion with hemoglobin-based oxygen carriers for organ and tissue preservation, ex-vivo organ management and biomarker discovery.

The Goldman Sachs Group

Angel (individual)

0.40

Undisclosed

7.00

HBM Healthcare Investments, Noel Hall, Kevin Chow

The company develops an implantable electronic, sensor and electrode system for delivering chronic electrical stimulation for treating thoracic pressure augmentation. Developer of a monoclonal antibody for the treatment of chronic diseases.

Clark Enterprise

Israel Biotech Fund Undisclosed

Gary Yang

Undisclosed

24

Monthly Healthcare Review June 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Company Name

Last Financing Date

HQ Location

Vomaris Wound Care 09-Jun-2016

Tempe, AZ

V-Sense Medical Devices

21-Jun-2016

San Francisco, CA

Yourdost

27-Jun-2016

Bangalore, India

ZappyLab

29-Jun-2016

Berkeley, CA

ZY Therapeutics

14-Jun-2016

Cary, NC

Zygood

24-Jun-2016

Dayton, MD

Compiled by: Terence Yen Source: Pitchbook

Round

Angel (individual) Accelerator/ Incubator

Description

Developer of an antimicrobial wound dressing technology.

The company uses radar technology to develop a contact-less medical device to monitor and measure heart rate, respiratory rate and other vital signs. Early Stage VC Developer of a medical counseling application. The company's software offers psychological support that allows users to seek support from psychologists and other trained physicians. Angel The company develops applications such as PubChase, an app which (individual) recommends recently-published articles based on the authors and journals the user reads, and Protocols, a checklist utility designed specifically for experimental laboratory work. Angel The company specializes in pharmacotherapeutics and novel delivery (individual) models for developing therapeutics and drugs to improve the lives of patients suffering from rare and orphan diseases. Angel Developer and marketer of medical devices to cure pain. The company's (individual) device offers a drug-free palliative care for bad backs, nerve pain from chemotherapy and arthritic joint pain.

Last Financing Size (Millions)

3.00

Lead Investor(s)

Undisclosed

Undisclosed MedTech Innovator

1.20

SAIF partners

0.03

Undisclosed

6.00

Undisclosed

0.06

Undisclosed

25

Monthly Healthcare Review June 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Premier

Target

Date

Description

Transaction Value (Millions)

Sharon Hill, PA

07-Jun-2016

Provider of an online healthcare portal for prescription refills, prior authorization 75.00 forms and related healthcare services.

New Castle, DE

23-Jun-2016

36.00

WellCare Health Plans Advicare Health

Greenville, SC

01-Jun-2016

The company specializes in organic synthesis and synthesis of milligrams to kilogram quantities while supporting the pharmaceutical, bio materials and catalysts industries. Provider of managed care services. The company offers health maintenance and health insurance coverage to primary care physicians, specialists and hospitals.

QLT

Aegerion Pharmaceuticals (AEGR) Afferent Pharmaceuticals

Cambridge, MA

15-Jun-2016

The company engages in the development and commercialization of innovative therapies for patients with debilitating rare diseases.

Undisclosed

San Mateo, CA

09-Jun-2016

The company develops small molecule compounds that target P2X3 receptors for 1,300.00 the treatment of chronic pain, respiratory, and urological conditions.

Grupo Ferrer

Alexza

Mountain View, CA 21-Jun-2016

Pfizer

Anacor Pharmaceuticals Ariad Pharmaceuticals (Luxembourg) Asifac Vetpharma Auditz

Palo Alto, CA

24-Jun-2016

Lausanne, Switzerland

01-Jun-2016

Developer of novel products for the acute treatment of central nervous system 55.00 conditions. A biopharmaceutical company that develops topical applications of compounds to 5,200.00 treat fungal, bacterial and inflammatory diseases. Manufacturer of drugs for the treatment of blood cancers. 140.00

Mumbai, India Tampa, FL

25-Jun-2016 15-Jun-2016

Austin, TX

02-Jun-2016

Kirkland, Canada

09-Jun-2016

Universal Display

Merck

Incyte

Nutraplus India TransUnion CRH Medical

Searchlight Pharma

Acro Pharmaceutical Services Adesis

HQ Location

Austin Gastroenterology Anesthesia Associates Besins Healthcare Canada

Compiled by: Terence Yen Source: Pitchbook

Undisclosed

Provider of medicated drugs and pharmaceutical products. Undisclosed Provider of healthcare technology services. The company uses technology to help Undisclosed healthcare providers identify and recover payments. Provider of anesthesia services. The company provides anesthesia services to two Undisclosed ambulatory surgical centers in Austin, Texas.

The company's products include Femarelle, a natural, non-hormonal, purified soy Undisclosed extract indicated for the relief of menopausal symptoms and to support bone health.

26

Monthly Healthcare Review June 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Target

HQ Location

Date

Description

Transaction Value (Millions)

Charles River Laboratories International Blood Systems

Blue Stream Laboratories

Woburn, MA

27-Jun-2016

The company offers biopharmaceutical protein characterization, analytical testing, Undisclosed clone screening and development of complex biologics and biosimilars.

Bonfils Blood Center

Denver, CO

16-Jun-2016

Undisclosed

Mindoula Health

Care At Hand

San Francisco, CA

13-Jun-2016

McKesson

Change Healthcare Nashville, TN

Guangdong Biolight Meditech Company

Changzhou, China

28-Jun-2016

Medsphere Systems

Changzhou Huaye Minimal Invasive Medical Devices Company ChartLogic

Operator of a nonprofit community blood bank. The company provides blood and bone marrow donations to its healthcare partners, including hospitals. It also provides laboratory and transfusion services. The company offers an electronic health record (EHR) and workflow support system for home-based care agencies. Its platform is designed to help family members in accessing medical information via an online portal. The company's products are designed to capture, organize, and authenticate patient data during the scheduling and registration process. The company is engaged in manufacturing and distributing cardiopulmonary bypass and related blood processing equipment.

Salt Lake City, UT

30-Jun-2016

Undisclosed

ContraVir Pharmaceuticals Inspec

Ciclofilin Pharmaceuticals Claro (Japan)

San Diego, CA

13-Jun-2016

Aomori, Japan

30-Jun-2016

The company offers an electronic medical record system that consists of patient history, document management, case management and practice management to improve patient care. Developer of treatment and medicine for hepatitis B and C viruses that include cyclophilin inhibitors drug. The company designs, develops and manufactures medical imaging systems.

Icon

ClinicalRM

Hinckley, OH

30-Jun-2016

Undisclosed

Zimmer Biomet

Compression Therapy Concepts Curaspan

Eatontown, NJ

08-Jun-2016

Owner and operator of a contract research organization. The company offers research and regulatory services and focuses on clinical research, product development for biologics, drugs and devices. Distributor of medical products for the prevention of deep vein thrombosis.

Newton, MA

01-Jun-2016

Navihealth

Compiled by: Terence Yen Source: Pitchbook

29-Jun-2016

Undisclosed

4,450.00 9.20

17.00 0.16

Undisclosed

Provider of patient-transition networks for hospitals, post-acute providers, payers Undisclosed and suppliers to optimize patient care.

27

Monthly Healthcare Review June 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Target

HQ Location

Aleris Helse

Curato Rontgen

Shiken

Dentas (Model Cup Tokushima, Japan 27-Jun-2016 Business) Dr. Oestreich + Cologne, Germany 13-Jun-2016 Partner

Ergomed

Ambu

Oslo, Norway

Date

13-Jun-2016

ETView Medical (ETVW) Fedialis Medica

Misgav, Israel

18-Jun-2016

Marly-le-Roi, France

03-Jun-2016

Gedeon Richter

Finox

30-Jun-2016

Mercal Capital

Folia Biotech

Kirchberg, Switzerland Quebec, Canada

BTG

Galil Medical

Arden Hills, MN

15-Jun-2016

Merry X-Ray Corporation HealthRight

Health Tech

Wilmington, NC

03-Jun-2016

HealthNEXT

Unionville, PA

30-Jun-2016

Medtronic

Heartware International (HTWR)

Framingham, MA

27-Jun-2016

Advanced Biological Laboratories

Compiled by: Terence Yen Source: Pitchbook

27-Jun-2016

Description

Transaction Value (Millions)

The company provides research and development services within pharmaceuticals Undisclosed and osteoporosis. It provides x-ray, magnetic resonance, mammography, computer tomography and ultrasound diagnostics services. Manufacturer of dental equipment.

0.08

Undisclosed The company manufacturers pharmaceutical products, diagnostic equipment, medical technology, cosmetics, food and non-food items and consumer products to clinics, insurance companies, professional organizations and official agencies. Manufacturer of medical imaging products such as VivaSight SL, DL, Direct and related medical accessories. The company offers a software for patient disease management that provide French healthcare professionals instant access to accurate demographics, medical history and latest laboratory results, in real-time. Operator of a biopharmaceutical company. The company develops fertility drugs and patient friendly delivery devices. Provider of biopharmaceutical services. The company's technology is a potent TLR7 agonist which can be used as an immunomodulating agent or as a vaccine platform. Developer of cryotherapy systems and disposable products to treat kidney, prostate and other types of cancer. Supplier of digital imaging products for the healthcare sector.

16.00 Undisclosed

194.34 Undisclosed

110.00 Undisclosed

Developer of workforce population health strategies. The company has developed Undisclosed a Six Sigma approach to population health that breaks each constituent component of the employee healthcare experience into a series of data points that can be tracked over time. Manufacturer of medical supplies and diagnostic equipment. The company 1,100.00 engages in manufacturing heart pumps, pacemakers, ventricular assist devices and artificial heart valves.

28

Monthly Healthcare Review June 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Target

HQ Location

Date

Fresenius, Smiths Group Teladoc

Hospira (Infusion Pump Business) HY Holdings

Lake Forest, IL

24-Jun-2016

Phoenix, AZ

30-Jun-2016

Oxford Immunotec Global Alphaeon

Imugen

Norwood, MA

23-Jun-2016

Integrity Digital Solutions

Temple, TX

02-Jun-2016

Sartorius

IntelliCyt

Albuquerque, NM

27-Jun-2016

American Diabetes Association

Intelligent Medical Decisions

Media, PA

10-Jun-2016

VWR International

JM Separations

Tilburg, Netherlands

02-Jun-2016

Telcon Co

Joongwon North Pharmaceuticals Co. Chungcheong, South Korea Keysource Medical Cincinnati, OH

Laboratoires ANIOS LDR Holding

Friedman Capital, Seal Rock Partners, Albert Paonessa III, Ms.Stephanie Ring Ecolab Zimmer Biomet

Compiled by: Terence Yen Source: Pitchbook

Description

Transaction Value (Millions)

Provider of computerized medical devices that deliver fluids, such as nutrients and 1,500.00 medications, into a patient's body in controlled amounts. Provider of healthcare consulting services. The company offers 24-hour access to 80.00 licensed physicians for webcam, telephone and e-mail consultations. Provider of clinical laboratory testing services. The company conducts research for tick-borne diseases such as testing of Lyme diseases. The company provides integrity electronic medical records systems that enables ophthalmology and optometrists to manage clinical workflow and patient engagement. The company develops high-throughput, high-content cell and bead-based screening used in phenotypic drug discovery, antibody discovery and in-vitro toxicity testing. Provider of healthcare improvement consultancy services. The company provides medical education, training, performance and quality improvement consultancy services to the healthcare industry. The company supplies single-use bag systems for media/buffer preparation, cell harvesting and for the clarification, concentration and chromatographic processes.

32.23

14-Jun-2016

Manufacturer of pharmaceutical products.

Undisclosed

06-Jun-2016

Distributor of generic pharmaceuticals. The company through its sales force offers Undisclosed generic pharmaceuticals and information about the generic drug industry to independent and chain pharmacies.

Lille, France

29-Jun-2016

Manufacturer and marketer of hygiene products for hospitals and healthcare units. 876.55

Austin, TX

07-Jun-2016

Operator of a medical device company focused on designing and commercializing 1,000.00 novel and proprietary surgical technologies for the treatment of patients suffering from spine disorders.

Undisclosed

90.00

Undisclosed

Undisclosed

29

Monthly Healthcare Review June 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Target

HQ Location

Date

MediBeacon

Mannheim Pharma Mannheim, and Diagnostics Germany

08-Jun-2016

The Hearst

MedHOK

Tampa, FL

13-Jun-2016

Medina International Holdings

Medical Innovation Miami, FL Holdings

08-Jun-2016

Kimball Electronics

Medivative Technologies

Indianapolis, IN

07-Jun-2016

Merck Serano

Merck Serano (Pakistan)

Karachi, Pakistan

24-Jun-2016

Dentsply International MIS Implants Technologies

Shlomi, Israel

27-Jun-2016

Ross & Baruzzini

Northbrook, IL

24-Jun-2016

Bunzl

Mitchell Planning Associates Mohage

Berlin, Germany

29-Jun-2016

Luminex

Nanosphere

Northbrook, IL

30-Jun-2016

Probi USA

Nutraceutix

Redmond, WA

06-Jun-2016

Compiled by: Terence Yen Source: Pitchbook

Description

The company provides a device that enables users to calculate and track the animal's kidney function over time without requiring the animal to be restrained during monitoring. The company's software platform helps health plans to ensure compliance with federal and state requirements, and manage the health plan members' clinical requirements. Provider of virtual medical consultation to its customers.

Transaction Value (Millions)

Undisclosed

Undisclosed

4.20

Manufacturer and distributor of medical devices. The company specializes in sheet 8.30 metal, injection molding, machining, tooling, welding and offers medical capital equipment, combination products and surgical devices. The company engages in manufacturing of pharmaceutical products and Undisclosed specializes in treatment of cancer, neurodegenerative diseases, infertility, endocrine and metabolic disorders, cardiovascular diseases and other conditions. Manufacturer of dental implants and superstructures. The company offers abutments, orthodontic screws, drills, crest wideners and prosthetics, as well as accessories, such as surgical instruments and kits. The company offers a diverse portfolio of medical equipment planning, procurement, installation and relocation services. The company engages in the distribution of medical devices, tools and maintenance materials for the treatment of spinal cord injury, multiple sclerosis, herniated disc and spina bifida. The company engages in research and development of a diagnostic test platform that helps in disease detection, optimal patient treatment and improved healthcare economics. Manufacturer of probiotics and nutritional supplements. The company produces probiotic powders, probiotics and nutraceuticals in capsules and tablets.

375.00

Undisclosed Undisclosed

102.00

105.00

30

Monthly Healthcare Review June 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Target

HQ Location

Date

Description

Transaction Value (Millions)

Eizo Corporation

Panasonic Tokyo, Japan Healthcare (Endoscopic Video Monitor Business)

06-Jun-2016

Developer and manufacturer of 3D and 4K endoscopic video monitoring equipment used to examine a person's digestive tract.

AMN Healthcare Services

Peak Health Solutions

Franklin, TN

06-Jun-2016

Genesis Capital

Quinta-Analytica

10-Jun-2016

Mylan

Renaissance Acquisition (Generics Business)

Prague, Czech Republic Longueuil, Canada

Provider of health information management services. The company offers coding, Undisclosed auditing and education services for healthcare organization’s budget. It also provides medical record review systems. The company provides research and development and regulatory services for Undisclosed pharmaceutical, biotechnology and generic drug industries. Provider of pharmaceutical services. The company manufactures, develops and 1,000.00 markets branded and generic topical pharmaceutical products which are prescribed for dermatological conditions.

1077801 B.C.

Response Biomedical (RBM)

Vancouver, Canada 16-Jun-2016

The company's The RAMP Platform is a lateral flow immunoassay platform that Undisclosed provides diagnostic information in minutes and has applications in cardiovascular and infectious disease tests that provide lab quality results quickly.

Medtronic

Responsive Orthopedics

Minneapolis, MN

07-Jun-2016

Magic Software Enterprises

Roshtov Software Industries (RSTV)

Omer, Israel

20-Jun-2016

The company specializes in selling knee and hip devices to hospitals involved in Undisclosed government cost-cutting programs. It also focused on designing Total Knee Systems in the healthcare industry and offers logistical support to physician practices and hospitals. Developer of a medical information platform which facilitates patient charting, the 21.32 documentation process, lab orders, referrals and laboratory test orders.

Green Cross Services, Inc.

Royal Trade Corp.

Port Orchard, WA 08-Jun-2016

Terumo

Sequent Medical

Aliso Viejo, CA

Compiled by: Terence Yen Source: Pitchbook

15-Jun-2016

14-Jun-2016

Undisclosed

Maker of first-to-market cannabidiol (CBD) health products. The company makes Undisclosed first-to-market CBD products and formulations. They develop naturally grown and refined pure CBD Isolate (99.8% purity) formulations and medicinal grade products. The company develops Microbraid technology to create a web aneurysm 380.00 embolization system for the treatment of both ruptured and unruptured aneurysms.

31

Monthly Healthcare Review June 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Target

HQ Location

Date

Vectura Group

Skyepharma

London, United Kingdom

10-Jun-2016

Laboratorios Roemmers

Spefar

Montevideo, Uruguay

24-Jun-2016

AJ Biologics

Statens Serum Institute (Vaccine Production Business) Stemcentrx

Copenhagen, Denmark

03-Jun-2016

San Francisco, CA

01-Jun-2016

Accelovance

THERAMetrics Holding

Stans, Switzerland

16-Jun-2016

Evonik Industries

Transferra Nanosciences

Burnaby, Canada

28-Jun-2016

OPKO Health

Transition Toronto, Canada Therapeutics (TTH)

30-Jun-2016

Lonza Group

Triangle Research Labs

30-Jun-2016

Strides Shasun

Universal Kikuyu, Kenya Corporation(Kenya)

Brenntag

Warren Chem Specialities

AbbVie

Compiled by: Terence Yen Source: Pitchbook

Raleigh, NC

07-Jun-2016

Cape Town, South 29-Jun-2016 Africa

Description

Transaction Value (Millions)

A drug delivery company engaged in the research, development, manufacture and 679.50 sale of prescription pharmaceutical products. It also develops oral and inhalation products. The company is engaged in the manufacturing, marketing and sale of 38.04 pharmaceutical drugs such as antibiotics, antispasmodics, anti allergic products, muscle relaxants and nutritional supplements. Manufacturer of vaccines. The business offers the Inactivated Poliovirus Vaccine Undisclosed and the Bacillus Calmette–Guérin vaccine.

The company provides therapies to eliminate cancer stem cells, which initiate and perpetuate tumors. It is investigating a number of the largest and most lethal cancers through its proprietary platforms that identify cancer stem cells and discover novel targets. The company offers technology services to life science and pharmaceutical companies through the entire value chain of the drug discovery and development process. The company offers range chemistry manufacturing and development services to biotechnology companies using complex drug delivery systems using lipid nanoparticle science. Developer of therapeutics for disease indications. The company provides a product for the treatment of Alzheimer’s disease and for the treatment of diabetes. The company provides hepatocytes for multiple research applications. Its product supports vitro evaluation of metabolism, drug-drug interactions, drug transporter activity, toxicity of drug candidates and other applications. The company manufactures over 100 formulations of human medicines. It includes a variety of doses in the form of doses, capsules, ointments, creams and powder. Supplier of raw materials for the pharmaceutical, nutraceutical, food, beverage, wine and chemical industries.

10,800.00

Undisclosed

Undisclosed

60.00

Undisclosed

14.00

Undisclosed

32

Monthly Healthcare Review June 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Pilgrim Capital Partners, Brookside Mezzanine Partners New Harbor Capital

Target

HQ Location

Date

Description

Transaction Value (Millions)

Water-Jel Technologies

Carlstadt, NJ

28-Jun-2016

Manufacturer and distributor of burn-care and other first-aid products for the industrial, military and consumer markets.

Undisclosed

Wedgewood Pharmacy

Swedesboro, NJ

08-Jun-2016

The company prepares customized medications for people and their pets when the food and drug administration manufactured drugs cannot meet their needs.

Undisclosed

PetalMD

Workoptics

Mississauga, Canada 22-Jun-2016

Goldsearch

Zoono Group

Écart Invest

Zorg Invest

Auckland, New Zealand Utrecht, Netherlands

Compiled by: Terence Yen Source: Pitchbook

27-Jun-2016 01-Jun-2016

The company operates as a cloud-based workforce management platform which Undisclosed offers services for staff scheduling in healthcare. It also offers savings in preparing, publishing and managing employee work schedules. Manufacturer and distributor of pharmaceutical products. The company provides Undisclosed clinical research and development of antimicrobial medicines. The company provides a knowledge-based platform for displaying information Undisclosed technology services for satiating various needs in hospitals and other healthcare institutions.

33