Mine Yaman Aydin Girgin 1

Vl't. UiI . Ocr&:. (ZOOI). 17. " : 111 -89 PRENATAL VE POSTNATAL OONEMOE TAV~AN MioE FUNOUSU OZERiNOE I~IK MiKROSKOBiK iNCELEMELER' Mine Yaman 1@ A...
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Vl't. UiI . Ocr&:. (ZOOI). 17. " : 111 -89

PRENATAL VE POSTNATAL OONEMOE TAV~AN MioE FUNOUSU OZERiNOE I~IK MiKROSKOBiK iNCELEMELER'

Mine Yaman 1@

Aydin Girgin 1

Light Microscopic ln vestigations on the Fundic MUCOS'l of Rabbit Stomach at Prenatal and Postnatal Periods Ozel: Bu ~I~da 20 adel d~ ve 4 adet er1les were taken from fundus of stomach and processed for light mICroscopic in· vestlgatlonS. At the 19 th day of prenatal period ml'cosal epithelial layer surrounding the central lumen displayed stratified structure and surface of mucosa itself displayed a rough course. Also, althe 21st day of prenalal period, mucosal surface was irregular and the epithelium consisted of 2·3 cell layers. AI the 23 rd day of fetal period the mucosal epithelium was stratified and developing primary glands were first observed al this period. AI lhe 27 th day of the letal penod, epithelium had sImple columnar structure. At the 29 th day of fetal period, the mucosal surface was covered with a thin mucus layer whICh was strongly posilive for ak:ian blue. On the 1 st day of postnatal period, fundic mucosa conlinued its development and by the 20 day It has gained its mature structure. Key Words: FundIC region. rabbit stomach, histologic developmenl Giri~

Midenin embriyonal ve postnatal donemdeki geIi~iml, slcan ve fare olmak uzere pek yok hayvan ile insanlarda calt$t lml~ttr (Alan,1989; A~r ve ark.,1994: Deren, 1971: Furihata ve ark., 1973: Kataoka ve ark., 1990: Menard ve Arsenault, 1990). Ancak tav~n mlde fundusunun geli$imi uzerinde yapllml$ olan az saylda call$maya rastlanml$lIr (Bemadac ve ark.• 1991: Hay.vard, 1967). Insanda embriyonal d6nemin 4. haftastnda 6n baglrsagtn, septum transversum duzeyinde kraniale dognJ mekik biyiminde geni$lemesi ile mide taslagt of~ur (Kayah ve ark., 1992: Noden ve Lahunta, 1985; Ozer ve ark.,1996; Petorak, 1986; Sadler, 1993). Bu mKle laslagl yok kallt yada yalanct yok kalll epltel ile kaplanlf (De Lemos, 1977; Petorak, 1986). Ferbhzasyondan 6 -9 hafta sonra mide yukur1uklan (foveola gastrikalar) ~killenmeye ba$lar ve 11 -17. haltalardan .llbaren de yOzey epiteli lek kallt prizmatik bir yapl gOsterir. Bu evrede yOzey epltel hOcreleri yaGcJl~

ti$kinlerin yuzey hOcrelenne benzer ve PAS poZltl! reaksiyon veren nOtr glikozaminoglikanlan iyerirler (Deren. 1971). Dert ayltk fetOste rrude bezlen ktsa gOvdeli, 5-6. aylarda ise dallanmt$ oIarak g6zlenir (De Lemos, 1977). DoQumu takiben midenin lundus bez· Jerinin pariyetal, mOkoz boyun ve yOzey muk6z hlicreleri ile az saytdaki prensipal hOcreleri, eri$klnlerdekine benzer bir yap. sergiler (Deren, 1971). Slyaniar uzerinde yaptlan ara$tlrrnalarda (A~r ve ark., 1995: Yeomans ve Trier, 1976), fundus mukozastntn fetal donemin 14. gOnunden IliOOren lark· IIla~maya OO$tayarak yok kath bir epitel. blaslemik doku ve tunika seroza katmantannl itrerdigi bildirilml$tlf. Gebeligin ilk olarak 16. gunOnde primitif foveola gastrikalar g6zlenir (A~rve ark .• 1995). BaZI ara$tlfmalarda (A~r ve ark., 1994; A~r ve ark .. 1995) ise stcanlarda fetal d6nemin 17. gOnOnde epitel laOOkastn tn yok katll 01dugu kaydedilmi~tir. Tav~nlarda gebeligin l 8. gununde gastrik epitel yer yer yok kalil, ball bOlOmlerde (se ya· lanet yok kaUt bir yaptdadlr (Hayward, 1967). Bazt ara~-

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