Mental Health and Allied Services Formulary

Mental Health and Allied Services Formulary Medicine Class Medicine Formulation Related NICE Technology Appraisal (TA) ANXIOLYTICS & HYPNOTICS Bet...
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Mental Health and Allied Services Formulary Medicine Class

Medicine

Formulation

Related NICE Technology Appraisal (TA)

ANXIOLYTICS & HYPNOTICS Beta-blockers Alpha-Blockers Z Medicines

Chloral and Derivatives Clomethiazole Antihistamines

Melatonin Benzodiazepines

Propranolol Prazosin

 tablet 10 mg, 40mg  tablet 500microgram, 1mg, 2mg, 5mg

*Zopiclone (first line) *Zolpidem tartrate (second line)



tablet 3.75 mg, 7.5 mg



tablet 5 mg, 10 mg

*Zaleplon (second line) Chloral hydrate Chloral betaine Clomethiazole base Clomethizole edisilate Promethazine hydrochloride



Capsule 5mg, 10 mg



Circadin® Restricted use KidMel ® Restricted use



Diazepam

   

Chlordiazepoxide



mixture 500 mg/ 5 mL tablet 707 mg capsule 192 mg syrup 250 mg/ 5 mL tablet 10 mg, 25 mg elixir 5 mg/ 5 mL injection 25mg/ml Tablets, m/r, melatonin 2 mg Melatonin 1mg/ml oral solution, alcohol free tablet 2 mg, 5 mg, 10 mg liquid 2 mg/ 5 mL, 5 mg/ 5 mL rectal tubes (=rectal solution) 5mg, 10mg injection emulsion 5 mg/ mL (Diazemuls®) capsule 5mg, 10mg

Lorazepam

 

Oxazepam Clonazepam (unlicensed use)

      

*TA077 Insomnia – newer hypnotic drugs. Zaleplon, zolpidem and zopiclone for the shortterm management of insomnia http://guidance.nice.org.uk/TA77

tablet 1 mg injection 4 mg/ mL  tablet 10 mg, 15 mg  

Nitrazepam

tablet 500 micrograms, 2 mg liquid 500 microgram/ 5mL; 2 mg/ 5mL (ULM)  tablet 5 mg

Loprazolam



tablet 1 mg

Lormetazepam



tablet 500 micrograms, 1 mg

Mental Health and Allied Services Formulary External Trustnet Created: March 2013 Updated Feb 2015 [Version 01.10.0] © Copyright 2015 CNWL NHS Foundation Trust Not to be used for commercial purposes

Medicine Class

Buspirone

Medicine

Formulation

Temazepam



tablet 10 mg, 20 mg

Midazolam



oromucosal solution, 5 mg/ mL

Diazepam Buspirone hydrochloride



rectal tubes (=rectal solution) 2.5 mg, 5 mg, 10 mg



tablet 5 mg, 10 mg

                

tablet 25 mg, 50 mg, 100 mg oral solution 25 mg/ 5mL, 100mg/ 5mL The injection should NOT be used. tablet 3 mg capsule 500 micrograms tablet 500 micrograms, 1.5 mg, 5 mg, 10mg liquid 1mg/ mL, 2mg/ mL injection 5mg/ mL tablet 200 mg, 400 mg oral solution 200mg/ 5mL tablet 1 mg, 5 mg solution 5 mg/ 5 mL tablet 2 mg, 10 mg, 25mg tablet 4mg tablet 25mg, 50mg oral solution 25 mg/ 5 mL injection 50mg/ 1mL, 100 mg/ 2mL

    

tablet 50 mg, 100 mg, 200mg, 400mg liquid 100 mg/mL tablet 5 mg, 10 mg, 15 mg orodispersible tablets 10 mg, 15 mg injection 7.5 mg/mL (1.3ml (9.75 mg) vial)

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ANTIPSYCHOTIC MEDICINES Typical - antipsychotics

Chlorpromazine hydrochloride

Flupentixol dihydrochloride Haloperidol

Sulpiride Trifluoperazine hydrochloride Zuclopenthixol dihydrochloride Pimozide Promazine hydrochloride

Atypical antipsychotics

Zuclopenthixol acetate (Clopixol Acuphase) Amisulpride *Aripiprazole

*Schizophrenia - aripiprazole (TA213) in people aged 15 to 17 years. http://guidance.nice.org.uk/TA213 *Bipolar I disorder – aripiprazole (TA292) in adolescents aged 13 years and older http://guidance.nice.org.uk/TA292

Mental Health and Allied Services Formulary External Trustnet Created: March 2013 Updated Feb 2015 [Version 01.10.0] © Copyright 2015 CNWL NHS Foundation Trust Not to be used for commercial purposes

Medicine Class

Medicine

Formulation

Risperidone



    

tablet 500 micrograms, 1 mg, 2 mg, 3 mg, 4 mg, 6 mg orodispersible tablet 500 micrograms, 1 mg, 2 mg, 3 mg, 4 mg liquid 1mg/ mL tablet 2.5 mg, 5 mg, 7.5mg, 10 mg, 15 mg, 20 mg orodispersible tablet 5 mg, 10 mg, 15 mg, 20 mg injection (Zyprexa®) 5 mg/ mL (10 mg vial) tablet 25 mg, 100 mg, 150 mg, 200 mg, 300 mg XL tablets 50 mg, 200 mg, 300 mg, 400 mg tablet 25 mg, 100 mg injection 20mg/ mL, 40mg/ 2mL injection (Depixol conc) 50mg/ 0.5 mL, 100mg/ mL injection (Depixol Low Volume) 200mg/ mL injection 12.5 mg/ 0.5mL, 25 mg/ 1mL injection (Modecate conc) 50 mg/ 0.5mL, 100 mg/ 1mL injection 50 mg/ mL, 100 mg/ mL injection 50 mg/ 1mL, 100 mg/ 2mL injection 200 mg/ mL injection (Clopixol conc) 500 mg/ mL injection 50 mg, 75 mg, 100 mg, 150 mg



Injection 400mg



tablet (Priadel ) 200 mg, 400 mg



Olanzapine

Quetiapine

Depot Antipsychotics – typical

Clozapine Flupentixol decanoate

Fluphenazine decanoate

Haloperidol decanoate Pipotiazine palmitate Zuclopenthixol decanoate Depot Antipsychotics atypicals

Paliperidone palmitate depot Aripiprazole long acting injection

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           

ANTIMANIC MEDICINES Antipsychotics

Benzodiazepines

Lithium

Haloperidol, aripiprazole, olanzapine, quetiapine risperidone Diazepam, chlordiazepoxide, lorazepam, oxazepam, clonazepam Lithium carbonate



Mental Health and Allied Services Formulary External Trustnet Created: March 2013 Updated Feb 2015 [Version 01.10.0] © Copyright 2015 CNWL NHS Foundation Trust Not to be used for commercial purposes

Medicine Class

Medicine

Formulation

Lithium citrate



Valproic acid

Sodium valproate (first line)

Carbamazepine

*Semisodium valproate (second line) Carbamazepine

Lamotrigine

Lamotrigine

Related NICE Technology Appraisal (TA) 

     

liquid (Li-liquid ) 509 mg/5 mL  liquid (Priadel ) 520 mg/5 mL tablet crushable 100 mg tablet e/c 200 mg, 500 mg tablet MR 200 mg, 300 mg, 500 mg liquid 200 mg/ 5 mL tablet e/c 250 mg, 500 mg

    

tablets 100 mg, 200 mg, 400 mg tablet MR 200 mg, 400 mg liquid 100 mg/ 5mL tablets 25 mg, 50 mg, 100 mg, 200 mg dispersible tablets 5 mg, 25 mg, 100 mg

   

tablet 10 mg, 25 mg, 50 mg liquid 25 mg/ mL capsule 25 mg tablet 75 mg

             

capsule 10 mg, 25 mg, 50 mg tablet 10 mg, 25 mg tablet 70 mg liquid 70 mg/ 5mL tablet 10 mg, 25 mg tablet 10 mg, 25 mg capsules 50 mg tablet 10 mg, 20 mg, 30 mg capsule 50 mg, 100 mg tablet 150 mg liquid 50 mg/ mL tablet 15 mg tablet 150 mg, 300 mg tablet 10 mg, 20 mg, 40 mg

 

liquid (Cipramil oral drops) 40 mg/ mL tablet 5 mg, 10 mg, 20 mg

ANTIDEPRESSANT MEDICINES Tricyclics antidepressants

Amitriptyline hydrochloride Dosulepin (dothiepin) hydrochloride “Less suitable for prescribing”1 Clomipramine hydrochloride Imipramine hydrochloride Lofepramine Nortriptyline Trimipramine

Related Antidepressants

Mianserin hydrochloride Trazodone hydrochloride

MAOIs Reversible MAOIs SSRIs

Phenelzine Moclobemide Citalopram hydrobromide Citalopram hydrochloride Escitalopram - restricted use



Mental Health and Allied Services Formulary External Trustnet Created: March 2013 Updated Feb 2015 [Version 01.10.0] © Copyright 2015 CNWL NHS Foundation Trust Not to be used for commercial purposes

Medicine Class

Medicine

Formulation

Fluoxetine

         

capsule 20 mg liquid 20 mg/ 5 mL dispersible tablet 20mg tablet 50 mg, 100 mg tablet 10 mg, 20 mg, 30 mg liquid 10 mg/ mL tablet 50 mg, 100 mg tablet 15mg, 30 mg, 45 mg orodispersible tablet 15 mg, 30 mg, 45 mg tablet 4 mg

Venlafaxine

 

tablet 37.5 mg, 75 mg capsule XL 75 mg, 150 mg

Pregabalin



Capsules, 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, 300 mg

Fluvoxamine Paroxetine

Presynaptic 2adrenoceptor blocker Selective noradrenaline reuptake inhibitor Serotonin and noradrenaline re-uptake inhibitor Antiepileptic

Sertraline Mirtazapine Reboxetine

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CNS STIMULATANTS AND MEDICINES USED FOR ADHD CNS Stimulants

*Dexamfetamine sulphate *Methylphenidate hydrochloride



tablet 5 mg



Lisdexamfetamine mesilate



tablet 5 mg, 10 mg (immediate release preparations)  Concerta XL tablets [22/78], 18 mg, 27 mg, 36 mg Equasym XL capsules [30/70], 10 mg, 20 mg, 30 mg Medikinet XL capsules [50/50], 5 mg, 10 mg, 20 mg, 30 mg, 40 mg capsule 30mg, 50mg, 70mg

*Atomoxetine



capsule 10 mg, 18 mg, 25 mg, 40 mg, 60 mg

  

Non-CNS Stimulants

*Attention deficit hyperactivity disorder (ADHD) methylphenidate, atomoxetine and dexamfetamine (review) (TA98). http://guidance.nice.org.uk/TA98

DOPAMINERGIC DRUGS USED IN PARKINSON'S DISEASE

Mental Health and Allied Services Formulary External Trustnet Created: March 2013 Updated Feb 2015 [Version 01.10.0] © Copyright 2015 CNWL NHS Foundation Trust Not to be used for commercial purposes

Medicine Class

Medicine

Formulation

Dopamine Agonists Amantadine

Bromocriptine Cabergoline Amantadine

-

Related NICE Technology Appraisal (TA)

tablet 1mg, 2.5mg, 5mg tablet 500microgram, 1mg, 2mg  Capsules 100mg

ANTIMUSCARINIC MEDICINES Hyoscine hydrobromide (Scopolamine Hydrobromide) Benzatropine

Chewable tablet (Kwells) 300 micrograms Scopoderm TTS patch 1 mg/ 72 hours injection 1 mg/ mL

Orphenadrine

tablet 50 mg liquid 50 mg/ 5mL tablet 5 mg liquid 2.5 mg/ 5 mL injection 5 mg/ 1mL tablet 2 mg, 5 mg liquid 5 mg/5 mL

Procyclidine

Trihexyphenidyl (benzhexol hydrochloride)

MEDICINES USED FOR DEPENDENCE Alcohol Dependence

Medicines for Opioid Dependence

Acamprosate Disulfiram Chlordiazepoxide Oxazepam, diazepam and lorazepam Naltrexone Nalmefene – restricted use Baclofen Methadone

Buprenorphine (Subutex®) Buprenorphine/ naloxone (Suboxone®) Lofexidine

  

tablet 333 mg tablet 200 mg capsule 5mg, 10mg  See section 4.1.2         

Tablet 50 mg Tablet 18mg tablets 10mg oral solution 1 mg/ mL sugar-free oral solution DTF 1mg/ mL oral solution 10 mg/ mL – restricted use injection 10 mg/ mL, 50 mg/ mL – restricted use tablet 5mg – off label tablet sublingual 400 micrograms, 2 mg, 8 mg

Nalmefene for reducing alcohol consumption in people with alcohol dependence - guidance (TA325) https://www.nice.org.uk/guidance/ta325

*Drug misuse - methadone and buprenorphine (TA114) http://guidance.nice.org.uk/TA114



tablet sublingual 2 mg/ 500 micrograms, 8 mg/ 2 mg  tablet 200 micrograms

Mental Health and Allied Services Formulary External Trustnet Created: March 2013 Updated Feb 2015 [Version 01.10.0] © Copyright 2015 CNWL NHS Foundation Trust Not to be used for commercial purposes

Medicine Class

Medicines for Cigarette Smoking Cessation

Medicine

Formulation

Related NICE Technology Appraisal (TA)

Naltrexone



tablet 50 mg

Drug misuse - naltrexone (TA115) http://guidance.nice.org.uk/TA115

Diamorphine injection Bupropion (Zyban®)



injection 10 mg, 30 mg tablet 150 mg

Varenicline (Champix®) Nicotine: gum, lozenges, inhalator, oral film and patches

    



   

Tablet 500 micrograms, 1 mg Nicorette® invisipatches (10 mg, 15 mg, 25 mg) Nicotinell® Patches (‘10’, ‘20’, ‘30’) Nicorette® Gum various flavours (2 mg, 4 mg); Nicotinell® Chewing gum various flavours (2 mg, 4 mg); Nicorette® Inhalator (15 mg per cartridge); Nicotinell® lozenge mint flavour (1 mg, 2 mg); Nicorette® lozenge mint flavour (2 mg); NiQuitin® Strips mint flavour (2.5mg)

         

tablet 5 mg, 10 mg tablet orodispersible 5 mg, 10 mg tablet 8 mg, 12 mg capsules MR 8 mg, 16 mg, 24 mg solution 4 mg/ mL capsules 1.5 mg, 3 mg, 4.5 mg, 6 mg solution 2 mg/mL patch 4.6 mg/ 24 hours, 9.5 mg/ 24 hours Tablets, 10 mg, 20 mg Solution 5 mg/ actuation (10mg/ mL)



oromucosal solution, 5 mg/ mL rectal tubes (=rectal solution) 2.5 mg, 5 mg, 10 mg

Smoking cessation - varenicline (TA123) http://guidance.nice.org.uk/TA123

MEDICINES USED IN DEMENTIA Acetylcholinesterase inhibiting Medicines

*Donepezil hydrochloride *Galantamine

*Rivastigmine

Glutamate receptor antagonist

*Memantine

*Alzheimer's disease - donepezil, galantamine, rivastigmine and memantine (TA217). http://guidance.nice.org.uk/TA217

MEDICINES USED IN STATUS EPILEPTICUS Benzodiazepines

Midazolam Diazepam



MEDICINES USED FOR ERECTILE DYSFUNCTION

Mental Health and Allied Services Formulary External Trustnet Created: March 2013 Updated Feb 2015 [Version 01.10.0] © Copyright 2015 CNWL NHS Foundation Trust Not to be used for commercial purposes

Medicine Class

Medicine

Formulation

Phosphodiesterase type-5 inhibitors

Sildenafil citrate Tadalafil Vardenafil

tablet (Viagra®) 25 mg, 50 mg, 100 mg tablet (Cialis®) 10 mg, 20 mg tablet (Levitra®) 5 mg, 10 mg, 20 mg

Related NICE Technology Appraisal (TA)

Mental Health and Allied Services Formulary External Trustnet Created: March 2013 Updated Feb 2015 [Version 01.10.0] © Copyright 2015 CNWL NHS Foundation Trust Not to be used for commercial purposes