CURRICULUM VITAE
PERSONAL Name Nationality Date of birth Private Address Phone Number (work) Mobile Phone E-‐mail Website Marital status EDUCATION 2009-‐2011 1999
Dr. Martijn Arns Dutch 4th December 1974, Apeldoorn
De Ravenberg 12 6573 DZ Beek-‐Ubbergen The Netherlands +31-‐24 7503505 +31-‐6 48177919
[email protected] www.brainclinics.com Married, 2 children
PhD at University of Utrecht, Department Experimental Psychology PhD at Radboud University Nijmegen and Organon Laboratories Ltd. – Scotland (not finished) Master Biological Psychology -‐ Radboud University Nijmegen VWO ‘Lyceum de Grundel’ -‐ Hengelo HAVO ‘Lyceum de Grundel’ -‐ Hengelo MLO ‘Twents M.B.O. College’ -‐ Hengelo MAVO 'Maris Stella' – Borne
1994-‐1998 1993-‐1994 1992-‐1993 1991-‐1992 1989-‐1991 CERTIFICATES 2011 PhD (Doctorate) 2009 BCIA EEG: BCN 2008 QEEG-‐Diplomate (QEEG-‐D) 2007 PSYCHOLOOG NIP 2000 ITIL Foundation 2000 Microsoft Certified Consultant (MCP) 1998 Doctoral Psychology (MSc) 1994 VWO (State exam) 1991 MAVO MEMBER OF ORGANISATIONS IPEG – International Pharmaco EEG society iSAD Fellow – International Society for Affective Disorders AAAS – American Association for the Advancement of Science ECNS – EEG and Clinical Neuroscience SAN – Society for applied Neurosciences NIP – Dutch Institute for Psychologists ISNR – International Society for Neurofeedback and Research
WORKING EXPERIENCE Jan. 2008-‐current Principal Investigator on the iSPOT-‐ADHD and iSPOT-‐Depression trials in the Netherlands (Phase-‐IV trial). Multisite study aiming to collect data from 2014 patients with Depression, 500 patients with ADHD including genetics, EEG, (neuro-‐)psychological measures and prescription to antidepressants and stimulant medication. Oct. ’10 – current Treasurer at the International Pharmaco-‐EEG Society (IPEG), Non-‐profit. Jan. ’07 – current Director and founder of Psychologenpraktijk Brainclinics. Oct. ’01 – current Director and founder of Research Institute Brainclinics Nov. ’09 -‐ Dec. ‘11 PhD at Utrecht University, Department of Experimental Psychology: ‘Personalized medicine in ADHD and depression: A quest for EEG treatment predictors’ Supervised by: Prof. L. Kenemans and Dr. W.H.I.M. Drinkenburg Nov. ’09 – Sept. ’11 Senior Editor for the Journal of Neurotherapy: Investigations in Neuromodulation, Neurofeedback and Applied Neuroscience (Scientific Journal), Non-‐profit. Sept. ’09 – Sept ’11 International Member at Large for the International Society for Neurofeedback and Research (ISNR), Non-‐profit. Sept. ’07 – Sept. ’09 Chairman: Applied Neuroscience Foundation (conference organizer: Applied Neuroscience for healthy brain function, Nijmegen, 2007), Non-‐profit. Oct. ’02 – July ‘07 Director and founder of Brainquiry B.V. Jan. ’00 – Oct. ’01 Product Manager Triple P, Business Unit Enterprise Management Jan. '99 – Jul. '99 PhD at Radboud University Nijmegen and Organon Laboratories Ltd, Newhouse, Scotland): 'Correlations between cognitive processes and pharmacoelectroencephalographic activity of the brain' (not finished) Supervised by Prof. A.M.L. Coenen, Prof. J.M.H. Vossen, Dr. W.H.I.M. Drinkenburg en Dr. J.S.A. Andrews. Febr. '98 – Jul. '98 Master thesis at Max-‐Planck Institute für Psychiatrie, München, Germany: 'Excitotoxic hippocampal lesions disrupt allocentric spatial learning in mice: Effects of genetic background.' Supervised by Dr. T. Steckler and Prof. J.M.H. Vossen. Sept '97 -‐ Dec. '97 Extra curricular masters project at Westmead Hospital Sydney, Australia: 'Central and autonomic measures in normal controls, schizophrenic patients, Parkinson patients and ADHD patients.' Supervised by Dr. E. Gordon. Sept. '96 -‐ Aug. '97 Masters project at Radboud University Nijmegen: 'Altered information processing during slow wave sleep in rats.' Supervised by Prof. A.M.L. Coenen and Dr. W.H.I.M. Drinkenburg
ADVISORY FUNCTIONS AND AWARDS 2013 Local organizer Society for Applied Neuroscience (SAN) conference 2013 2012 Treasurer and co-‐organizer of IPEG 2012 conference in New York 2011 Awarded ISNR Presidential Award of Merit 2010 Awarded ISNR Joel F. Lubar Award 2010 FNAN Award for the year’s most significant publication on the field of Neurofeedback for ‘Efficacy of Neurofeedback treatment in ADHD: The effects on Inattention, Impulsivity and Hyperactivity: A meta-‐analysis’ 2009-‐2011 Advisor for the ISNR Research Foundation 2008 Awarded ISNR Fellow 2007-‐2010 Member of ISNR Conference Committee LANGUAGES Oral Written Dutch Fluent Good English Fluent Good German Reasonable Reasonable AUTHORSHIP ON PATENTS (no commercial interest) Arns & Spronk (2010) Method for assessing the susceptibility of a human individual suffering from a psychiatric or neurological disorder to neuromodulation treatment. WO/2010/139361 Arns, Slootweg & Kleinnijenhuis (2008) Apparatus for measuring one or more physiological functions of a body and a method using the same. US8077297 Arns & van Dorsten (2005) Een systeem en werkwijze voor het registreren van elektrische signalen die in een levend lichaam optreden: NL1024860.
SCIENTIFIC PUBLICATIONS (ALPHABETICAL ORDER; H-‐INDEX=14) 1. Alexander, D. M., Arns, M. W., Paul, R. H., Rowe, D. L., Cooper, N., Esser, A. H., et al. (2006). EEG markers for cognitive decline in elderly subjects with subjective memory complaints. Journal of Integrative Neuroscience, 5(1), 49-‐74. 2.
Arns, M. (2008). Personalized medicine: Nieuwe ontwikkelingen in de diagnostiek en behandeling van ADHD en depressie. De Psycholoog, (September).
3.
Arns, M. (2010a). Handboek neurofeedback bij ADHD. [Handbook Neurofeedback in ADHD] (1 ed.). SWP.
4.
Arns, M. (2010b). Historical archives: The beginning. Journal of Neurotherapy, 14(4), 291-‐ 292.
5.
Arns, M. (2012). EEG Based Personalized Medicine in ADHD: Individual alpha peak frequency as an endophenotype associated with non-‐response. Journal of Neurotherapy, 16, 123-‐241.
6.
Arns, M. (In Press) Personalised Medicine in ADHD and Depression: Use of Pharmaco-‐ EEG. In: Essentials and Applications of EEG in preclinical and clinical Pharmacology and Drug Development. Eds. Jobert, M & Drinkenburg, W.H.I.M
7.
Arns, M., Conners, K. & Kraemer, H. (2012). A decade of EEG Theta/Beta ratio research in ADHD: A meta-‐analysis. Journal of Attention Disorders. doi:10.1177/1087054712460087
8.
Arns, M. & de Ridder, D. (2011). Neurofeedback 2.0. Journal of Neurotherapy, 15(2), 91-‐ 93.
9.
Arns, M., de Ridder, S., Strehl, U., Breteler, M., & Coenen, A. (2009). Efficacy of neurofeedback treatment in ADHD: The effects on inattention, impulsivity and hyperactivity: A meta-‐analysis. Clinical EEG and Neuroscience, 40(3), 180-‐9.
10. Arns, M., Drinkenburg, W. H. I. M., & Kenemans, J. L. (2012). The effects of QEEG-‐informed neurofeedback in ADHD: An open label pilot study. Applied Psychophysiology and Biofeedback, 37; 171-‐180 11. Arns, M., Drinkenburg, W. H. I. M., Fitzgerald, P. B., & Kenemans, J. L. (2012). Neurophysiological predictors of treatment outcome to rTMS in depression. Brain Stimulation. doi: 10.1016/j.brs.2011.12.003 12. Arns, M., Heinrich, H. & Strehl, U. (submitted) Evaluation of neurofeedback in ADHD: The long and winding road. Biological Psychology 13. Arns, M. & Kenemans, J.L. (2012). Neurofeedback in ADHD and insomnia: Vigilance stabilization through sleep spindles and circadian networks. Neuroscience and Biobehavioral Reviews. doi: 10.1016/j.neubiorev.2012.10.006 14. Arns, M., Gunkelman, J., Breteler, M., & Spronk, D. (2008). EEG phenotypes predict treatment outcome to stimulants in children with ADHD. Journal of Integrative Neuroscience, 7(3), 421-‐38. 15. Arns, M., Gunkelman, J., Olbrich, S., Sander, C., & Hegerl, U. (2010). EEG vigilance and phenotypes in neuropsychiatry: Implications for intervention. In: Neuromodulation and neurofeedback: Techniques and applications (R. Coben & J. Evans, Eds.). Elsevier.
16. Arns, M., & Lyle, R. L. (2011). Neurofeedback and QEEG: The space-‐race. Journal of Neurotherapy, (15), 4. 17. Arns, M., Peters, S., Breteler, R., & Verhoeven, L. (2007). Different brain activation patterns in dyslexic children: Evidence from EEG power and coherence patterns for the double-‐deficit theory of dyslexia. Journal of Integrative Neuroscience, 6(1), 175-‐90. 18. Arns, M., Sauvage, M., & Steckler, T. (1999). Excitotoxic hippocampal lesions disrupt allocentric spatial learning in mice: Effects of strain and task demands. Behavioural Brain Research, 106(1-‐2), 151-‐64. 19. Arns, M., Spronk, D., & Fitzgerald, P. B. (2010). Potential differential effects of 9 Hz rTMS and 10 Hz rTMS in the treatment of depression. Brain Stimulation, (3), 124-‐126. 20. Arns, M., Van Luijtelaar, G., Sumich, A., Hamilton, R., & Gordon, E. (2007). Electroencephalographic, personality, and executive function measures associated with frequent mobile phone use. The International Journal of Neuroscience, 117(9), 1341-‐60. 21. Arns, M. W., Kleinnijenhuis, M., Fallahpour, K., & Breteler, M. H. M. (2008). Golf performance enhancement by means of ‘real-‐life neurofeedback’training based on personalized event-‐locked EEG profiles. Journal of Neurotherapy, 11(4), 11-‐18. 22. Breteler, M. H., Arns, M., Peters, S., Giepmans, I., & Verhoeven, L. (2010a). Erratum to: Improvements in spelling after QEEG-‐based neurofeedback in dyslexia: A randomized controlled treatment study. Applied Psychophysiology and Biofeedback, 35(2), 187. 23. Breteler, M. H., Arns, M., Peters, S., Giepmans, I., & Verhoeven, L. (2010b). Improvements in spelling after QEEG-‐based neurofeedback in dyslexia: A randomized controlled treatment study. Applied Psychophysiology and Biofeedback, 35(1), 5-‐11. 24. Breteler, Van Heeswijk, Arns, & Verdellen (2008). Psychologische interventies bij het syndroom van gilles de la tourette. Tijdschrift Voor Neuropsychiatrie & Gedragsneurologie, (Juli/Augustus). 25. Cerquera Soacha, A., Arns, M. Bolivar, E.B., Salamanca, R.M.G. & Freund, J.A. (2012) Nonlinear Dynamics Measures Applied to EEG Recordings of Patients with Attention Deficit/Hyperactivity Disorder: Quantifying the Effects of a Neurofeedback Treatment. 34th Annual International IEEE EMBS Conference 26. Clark, C. R., Paul, R. H., Williams, L. M., Arns, M., Fallahpour, K., Handmer, C., et al. (2006). Standardized assessment of cognitive functioning during development and aging using an automated touchscreen battery. Archives of Clinical Neuropsychology, 21(5), 449-‐67. 27. Coben, R., Arns, M., & Kouijzer, E. J. (2010). Enduring effects of neurofeedback in children. In: Neuromodulation and neurofeedback: Techniques and applications (R. Coben & J. Evans, Eds.). Elsevier. 28. Cortoos, A., De Valck, E., Arns, M., Breteler, M. H., & Cluydts, R. (2010). An exploratory study on the effects of tele-‐neurofeedback and tele-‐biofeedback on objective and subjective sleep in patients with primary insomnia. Applied Psychophysiology and Biofeedback, 35(2), 125-‐34. 29. Gunstad, J., Paul, R. H., Brickman, A. M., Cohen, R. A., Arns, M., Roe, D., et al. (2006). Patterns of cognitive performance in middle-‐aged and older adults: A cluster analytic
examination. Journal of Geriatric Psychiatry and Neurology, 19(2), 59-‐64. 30. Jongsma, M. L. A., Postma, S., Souren, P., Arns, M., Gordon, E., Vissers, K., . . . van Goor, H. (2011). Neurodegenerative properties of chronic pain: Cognitive decline in patients with chronic pancreatitis. Plos One, 6(8), e23363. doi:doi:10.1371/journal.pone.0023363 31. Kemp, A. H., Griffiths, K., Felmingham, K. L., Shankman, S. A., Drinkenburg, W. H. I. M., Arns, M., et al. (2010). Disorder specificity despite comorbidity: Resting EEG alpha asymmetry in major depressive disorder and post-‐traumatic stress disorder. Biological Psychology, 85(2), 350-‐354. 32. Kleinnijenhuis, M., Arns, M. W., Spronk, D. B., Breteler, M. H. M., & Duysens, J. E. J. (2008). Comparison of discrete-‐trial based SMR and SCP training and the interrelationship between SCP and SMR networks: Implications for brain-‐computer interfaces and neurofeedback. Journal of Neurotherapy, 11(4), 19-‐35. 33. Lansbergen, M., Arns, M., van Dongen-‐Boomsma, M., Spronk, D., & Buitelaar, J. K. (2011). The increase in theta/beta ratio on resting state EEG in boys with attention-‐ deficit/hyperactivity disorder is mediated by slow alpha peak frequency. Progress in Neuro-‐Psychopharmacology & Biological Psychiatry, 35, 47-‐52. 34. Liddell, B. J., Paul, R. H., Arns, M., Gordon, N., Kukla, M., Rowe, D., et al. (2007). Rates of decline distinguish Alzheimer's disease and mild cognitive impairment relative to normal aging: Integrating cognition and brain function. Journal of Integrative Neuroscience, 6(1), 141-‐74. 35. Sander, C., Arns, M., Olbrich, S., & Hegerl, U. (2010). EEG-‐Vigilance and response to stimulants in paediatric patients with attention deficit/hyperactivity disorder. Clinical Neurophysiology, 121, 1511-‐1518. 36. Sherlin, L., Arns, M., Lubar, J., Heinrich, H., Kerson, C., Strehl, U., & Sterman, M. B. (2011). Neurofeedback and basic learning theory: Implications for research and practice. Journal of Neurotherapy, 15(4), 292-‐304. 37. Sherlin, L., Arns, M., Lubar, J., & Sokhadze, E. (2010a). A reply to Lofthouse, Arnold, and Hurt (2010). Journal of Neurotherapy, 14(4), 307-‐311. 38. Sherlin, L., Arns, M., Lubar, J. F., & Sokhadze, E. (2010b). A position paper on neurofeedback for the treatment of ADHD. Journal of Neurotherapy, 14(2), 66-‐78. 39. Spronk, D. & Arns, M. (2009). rTMS bij depressie. Tijdschrift Voor Neuropsychiatrie & Gedragsneurologie, (Juli-‐Augustus). 40. Spronk, D., Arns, M., & Fitzgerald, P. B. (2010). Repetitive transcranial magnetic stimulation in depression: Protocols, mechanisms and new developments. In: Neuromodulation and neurofeedback: Techniques and applications (R. Coben & J. Evans, Eds.). Elsevier. 41. Spronk, D., Arns, M., Barnett, K. J., Cooper, N. J., & Gordon, E. (2011). An investigation of EEG, genetic and cognitive markers of treatment response to antidepressant medication in patients with major depressive disorder: A pilot study. Journal of Affective Disorders, 128, 41-‐48. 42. Spronk, D., Arns, M., Bootsma, A., van Ruth, R., & Fitzgerald, P. B. (2008). Long-‐Term
effects of left frontal rTMS on EEG and ERP’s in patients with depression. Clinical EEG and Neuroscience, 39(3), 118-‐24. 43. Spronk, D., Kleinnijenhuis, M., Luijtelaar, G., & Arns, M. (2010). Discrete-‐Trial SCP and GSR training and the interrelationship between central and peripheral arousal. Journal of Neurotherapy, 14(3), 217-‐228. 44. Spronk, D., Veth C.P.M., Arns, M., Schofield, P.R., Dobson-‐Stone, C., Ramaekers, J.G., Franke, B., de Bruijn, E.R.A. & Verkes, R.J. (2012). DBH-‐1021C>T and COMT Val108/158Met genotype are not associated with the P300 ERP in an auditory oddball task. Clinical Neurophysiology: doi: http://dx.doi.org/10.1016/j.clinph.2012.11.008 45. The Collaborative Neurofeedback Group (Arnold,L.E., Arns, M., Conners, K., DeBeus, R., Hirshberg, L., Kerson, C., Kraemer, H., Lofthouse, N., Lubar, J., McBurnett, K. & Monastra, V.) (Under revision) A proposed multi-‐site double-‐blind randomized clinical trial of neurofeedback for ADHD: Need, rationale and strategy. Journal of Attention Disorders. 46. Thomassen, F. & Arns, M. (2010). Are the effects of rTMS in Parkinson’s disease clinically relevant? Journal of Neurotherapy, 14(2), 96-‐101. 47. van den Bunt, M., Arns, M., Verbraak, M., Keijsers, G., & van Luijtelaar, G. (2010). Biomarkers bij burn-‐outpatiënten. Neuropraxis, 14, 165-‐173. 48. van Luijtelaar, G., Verbraak, M., van den Bunt, M., Keijsers, G., & Arns, M. (2010). EEG findings in burnout patients. The Journal of Neuropsychiatry and Clinical Neurosciences, 22(2), 208-‐17. 49. Williams, L. M., Gatt, J. M., Hatch, A., Palmer, D. M., Nagy, M., Rennie, C., Cooper, N.J., Morris, C., Grieve, S., Dobson-‐Stone, C., Schofield, P., Clark, C.R., Gordon, E., Arns, M. & Paul, R. (2008). The integrate model of emotion, thinking and self regulation: An application to the "paradox of aging". Journal of Integrative Neuroscience, 7(3), 367-‐404. 50. Winkelmolen, D., Kruiver, V. & Arns, M. (2012) Neurofeedback treatment in a client with ADHD and ODD. Biofeedback. 51. Zoon, H.F.A., Veth, C.P.M., Arns, M. Drinkenburg, W.H.I.M., Talloen, W., Peeters, P.J. & Kenemans, J.L. (In Press) EEG Alpha Power as an intermediate measure between BDNF Val66Met and Depression severity in patients with Major Depressive Disorder. Journal of Clinical Neurophysiology.