Mandatory Disclosure B.Pharmacy S.No . I
NAME
OF
THE SARADA
INSTITUION
SCIENCES,
COLLEGE
OF
PHARMACEUTICAL
KONDAKAVURU,
NARASARAOPET
MANDAL, GUNTUR DISTRICT PH : 9985762858, 9949419430 Mobile:-9866568134 Fax : E_mail :
[email protected] II
NAME AND ADDRESS Prof. V.S.Venkateswara Rao M.Pharm., Ph.D., M.B.A. OF THE DIRECTOR
Mobile:- 9985762858 Fax
III
NAME
OF
THE ACHARYA NAGARJUNA UNIVERSITY
AFFILIATING UNIVERSITY IV
GOVERNANCE Members of the Board and Yerram Venkateswara reddy – President their brief Back Ground
MLA, Sattenapalli. M.J.M. Rama Linga Reddy – Vice President Director of Sarada Junior College, Narasaraopet K.Venkata rao - Secretary Marine Engineer G.Padmavathi – Joint Secretary Director of Sarada Junior College, Narasaraopet B. R. Suseel Kumar – Treasurer Social Servant & Principal of sarada junior college, Narsaraopet B. Sanga Mitra – Member
1
Lecturer in Bio-Chemistry Raghu Ramaiah College, Narasaroapet J.Ramesh babu-member Lecturer in Pharmacy S.Sada Siva rao – Member Social servant. K. Koti Reddy – Member Director – NVR Junior Collge & CARE Public School
Members
of
Academic Prof. P.Ellaiah
Advisory Body
- Retd. Principal of College of
Pharmaceutical Sciences, Andhra Univeristy . J. Ramesh Babu – Asst. professor in Nagarjuna Educational Society’s Institute of Pharmacy. Rama Krishna – General Manager, Safe Pharmaceuticals
Frequency of the Board Yearly twice Meetings
and
Academic
Advisory Body Organizational
chart
and
Principal
process HOD
Nature
and
Extent
HOD
HOD
HOD
Office Supdt
Lecturers
Lecturers
Lecturers
Lecturers
Office Staff
Lab Staff
Lab Staff
Lab Staff
Lab Staff
of Faculty tries to use new methodology. They Provocate
involvement of faculty and research ability in students.
Students try to publish
students in academic affairs papers. / improvements Mechanism / Norms & Through the Principal We take feed back of all procedure for democratic /. grievances of Staff and Students Good governance
2
Student
Feedback
on Through The Principal we get Student Feedback on
Institutional Governance / Institutional Governance / Faculty performance Faculty performance Grievance
redressal Principal , Secretary and a Student Leader will constitute
mechanism for faculty, staff a committee for the Grievance redressal mechanism for and students V
faculty, staff and students
PROGRAMMES Name
of
the
Program Degree Pharmacy Program
approved by the AICTE Name
of
the
Programs Nil
accredited by the AICTE For
each
Program
the
following details are to be given : Name
B. Pharmacy
Number of seats
60
Duration
4 Years
Cut off mark / rank for Eamcet rank-1,43,271 for the year 2007-2008 admission during the last three years Fee
27,500.00 Rs.
Placement Facilities
During the 4th Year Management will arrange for Placements.
Campus placement in last Not applicable three years with minimum salary, maximum salary and average salary
Name
and
duration
of Not applicable
3
program(s)
having
affiliation / collaboration with Foreign University (s) / Institution (s) and being run in the same campus along with status of their AICTE approval. If there is foreign collaboration, give the following details : Details of the Foreign / Not applicable Institution Name of the University / Not applicable Institution Address
Not applicable
Website
Not applicable
Is
the
Institution
/ Not applicable
University Accredited in its Home country Ranking of the Institution / Not applicable University in the Home Country Whether the degree offered Not applicable is equivalent to an Indian Degree? If yes, the name of the
agency
which
approved equivalence.
has If
no, implications for students in terms of pursuit of higher studies in India and abroad and job both within outside the country
4
Nature of Collaboration
Not applicable
Condition of Collaboration
Not applicable
Complete
details
of Not applicable
payment a student has to make to get full benefit of collaboration. For each collaborative / Not applicable affiliated Program give the following Program Focus
Not applicable
Number of sets
Not applicable
Admission Procedure
Not applicable
Fee
Not applicable
Placement Faculty
Not applicable
Placement Record for last Not applicable three years with minimum salary, maximum salary and average salary. Whether the Collaborative Not applicable Programs is approved by AICTE?>
If not where
their Domestic / Foreign Institution has applied to AICTE for approval as required under notification No. 37-3/Legal/2005 dated 16th May, 2005 VI
FACULTY
Branch wise list faculty
5
members Permanent Faculty
Prof. V.S.Venkateswara Rao, M.Pharm., Ph.D., M.B.A. K.Sarath babu, M.Pharm
K.Anil Kumar, M.Pharm B.Raju, M.Pharm. P.N.V.Gopal, M.Pharm P.V.Madhava Reddy, M.Pharm. P.Arun Kumar, M.Pharm. P.Ravi, M.Pharm. T.Ramanji Reddy, M.Pharm. G.Surendra, M.Pharm. P.Lingeswara Rao, M.Pharm. S.Kotaiah, B.Pharm, M.Tech A.Anka Rao, M.Pharm P.Praveen Kumar, M.Pharm N.Mallikarjuna Rao, M.Pharm N.Kotaiah, M.Pharm Visiting Faculty
Prof. P. Ellaiah & Mrs. S.V.N.Padma
Adjunct Faculty
N.Ramakrishna Reddy, Fredric, V.Vasantha Babu. M.Ramaligareddy,
Guest Faculty
Prof. P.satyanarayana
Permanent Faculty : Student
1 : 15
Ratio Number
of
faculty
14
employed and left during the last three years VII
PROFILE OF DIRECTOR / PRINCIPAL
WITH
QUALIFICATIONS, TOTAL EXPERIENCE, AGE AND DURATION
OF
6
EMPLOYMENT
AT
THE
INSTITUTE CONCERNED
Name
Dr. V.S.Venkateswara Rao Principal
Date of Birth
30- 04- 1966
Educational Qualification
M.Pharmacy , Ph.D in Pharm.Bio-Tech, M.B.A.
Work Experience - Teaching
12 years
- Research
5 years
- Industry
Nil
-others
Nil
Area of Specialization
Pharmaceutical Biotechnology
Subjects teaching at Under Physical Pharmacy, Graduate Level Research Guidance
Nil
No. of Papers published in 4 Research papers National Journals Ph.D. International Journals
Nil
Conferences
22 presentations in 6 conferences and symposia
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
4 papers
7
For each Faculty give a page covering Name
B.Raju Sr.Lecturer
Date of Birth
10- 06- 1981
Educational Qualification
M.Pharmacy in pharmaceutical sciences
Work Experience - Teaching
4 years
- Research - Industry
One month training in Graduation Level
-others Area of Specialization
Pharmaceutical Technology
Subjects teaching at Under Pharmaceutical Engineering, Cosmetic technology Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
7 papers in conferences and symposiums
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
8
Number of Books published Nil with details Name
P.N.V.Gopal Sr.Lecturer
Date of Birth
28- 12- 1979
Educational Qualification
M.Pharmacy in pharmaceutical sciences
Work Experience - Teaching
4 years
- Research
Nil
- Industry
One month training at Graduation Level
-Others
Nil
Area of Specialization
Pharmaceutical Biotechnology
Subjects teaching at Under Pharmaceutical Analysis, Biopharmaceutics Graduate Level Research Guidance Nil No. of Papers published in 3 National Journals No. of Papers published in 1 paper in Biophysical and Biochemical Research International Journals Communications of Elsveir group of journals 1 paper in Journal of stem cells Ph.D. Conferences
5 papers in conferences and symposiums
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
9
Number of Books published Nil with details Name
N.Mallikarjuna Rao Lecturer
Date of Birth
11-03-1983
Educational Qualification
M.Pharmacy
Work Experience
Nil
- Teaching
Nil
- Research
-
- Industry
Nil
-others Area of Specialization
Pharmaceutical Analysis
Subjects teaching at Under Anatomy and physiology Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
-
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
10
Number of Books published Nil with details Name
K.Sarath Babu Asst.Professor
Date of Birth
30- 01- 1969
Educational Qualification
M.Pharmacy
Work Experience - Teaching
3 year
- Research
1 year
- Industry
11 years
-others Area of Specialization
Hospital Pharmacy
Subjects teaching at Under Dispensing, Hospital and clinical Pharmacy Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
Nil
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
11
Research Publications
Nil
Number of Books published Nil with details Name K.Anil Kumar Asst.Professor
Date of Birth
01/01/1973
Educational Qualification
M.Pharmacy in Bio-Technology
Work Experience - Teaching
12
- Research
Nil
- Industry
Nil
-others
Nil
Area of Specialization
Pharm.Bio-tech
Subjects teaching at Under Pharmaceutical Microbiology and Pharmaceutical BioGraduate Level
Technology
Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
10 papers in conferences and symposiums
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
12
Number of Books published Nil with details
13
Name
P.V.Madhava Reddy Lecturer
Date of Birth
05/06/1978
Educational Qualification
M.Pharmacy in pharmacology
Work Experience - Teaching
2 year
- Research
Nil
- Industry
Nil
-others
Nil
Area of Specialization
Pharmacology
Subjects teaching at Under Pharmacology, Anatomy and Physiology Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
10 papers in conferences and symposiums
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
Number of Books published Nil with details
14
Name
P.Arun Kumar Lecturer
Date of Birth
20/01/1979
Educational Qualification
M.Pharmacy in Ind.Pharmacy
Work Experience - Teaching
2 year
- Research
Nil
- Industry
Nil
-others
Nil
Area of Specialization
Ind.Pharmacy
Subjects teaching at Under Ind.Pharmacy, Management Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
10 papers in conferences and symposiums
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
Number of Books published Nil with details
15
Name
P.Ravi Lecturer
Date of Birth
25/06/1982
Educational Qualification
M.Pharmacy in Pharmacognosy
Work Experience - Teaching
2 year
- Research
Nil
- Industry
Nil
-others
Nil
Area of Specialization
Pharmacognosy
Subjects teaching at Under Pharmacognosy ,Natural Products Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
10 papers in conferences and symposiums
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
Number of Books published Nil with details 16
Name
A.AnkaRao Lecturer
Date of Birth
10-07-1983
Educational Qualification
M.Pharmacy in Pharmaceutics
Work Experience
Nil
- Teaching
1 year
- Research
Nil
- Industry
Nil
-others
Nil
Area of Specialization
Pharmaceutics
Subjects teaching at Under PharmChemistry, Organic Chemistry Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
Nil
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
Number of Books published Nil with details
17
Name
P.Praveen Kumar Lecturer
Date of Birth
18-06-1982
Educational Qualification
M.Pharm in Ind Pharmacy
Work Experience - Teaching
Nil
- Research
Nil
- Industry
Nil
-others
Nil
Area of Specialization
Industrial Pharmacy
Subjects teaching at Under Bio-Chemistry,Pharmaceutics Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
Nil
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
Number of Books published Nil with details
18
Name
G.Surendra Lecturer
Date of Birth
12-06-1978
Educational Qualification
M.Pharm in Pharmaceutical Chemistry
Work Experience - Teaching
1 year
- Research
Nil
- Industry
Nil
-others
Nil
Area of Specialization
Pharmaceutical Chemistry
Subjects teaching at Under Medicinal Chemistry Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
Nil
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
Number of Books published Nil
19
with details Name
T.Ramani Reddy Lecturer
Date of Birth
03-03-1983
Educational Qualification
M.Pharm in Pharmaceutics
Work Experience - Teaching
1 Year
- Research
Nil
- Industry
Nil
-others
Nil
Area of Specialization
Pharmaceutics
Subjects teaching at Under Pharmaceutics, Forensic Pharmacy Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
Nil
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
Number of Books published Nil
20
with details Name
P.Lingeswara Rao Lecturer
Date of Birth
10-05-1979
Educational Qualification
M.Pharm in Pharmaceutical Analysis
Work Experience - Teaching
1 Year
- Research
Nil
- Industry
Nil
-others
Nil
Area of Specialization
Pharmaceutical Analysis
Subjects teaching at Under Pharmaceutical Analysis Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
Nil
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
21
Number of Books published Nil with details Name
N.Kotaiah Letcher
Date of Birth
10-05-1983
Educational Qualification
M.Pharm in Quality Assurance
Work Experience - Teaching
Nil
- Research
Nil
- Industry
Nil
-others
Nil
Area of Specialization
Quality Assurance
Subjects teaching at Under Organic chemistry ,pharmaceutics Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D.
-
International Journals
Nil
Conferences
Nil
Projects Carried out
Nil
Patents
Nil
Technology Transfer
Nil
Research Publications
Nil
Number of Books published Nil
22
with details
Name
S.Kotaiah Lecturer
Date of Birth
15- 02- 1982
Educational Qualification
M.tech in Biotechnology, M.Pharm in Pharma cognosy
Work Experience
2 years
- Teaching
1 year
- Research
1 years
- Industry
One month training in Graduation Level
-others Area of Specialization
Biotechnology
Subjects teaching at Under Inorganic Chemistry Graduate Level Research Guidance
Nil
No. of Papers published in Nil National Journals
Nil
Ph.D. International Journals
Nil
Conferences
7 papers in Conferences and Symposiums
Projects Carried out
Nil
Patents
Nil
23
Technology Transfer
Nil
Research Publications
Nil
Number of Books published Nil with details VIII
FEE Details of fee, as approved
Rs.27,500.00
by State Fee Committee, for the Institution Time schedule for payment
During Admission
of fee for the entire program No. of Fee waivers granted
NIL
with amount and name of students. Number
of
scholarship
NIL
offered by the institute, duration and amount Criteria for fee waivers /
Income & Merit
scholarship Estimated cost of Boarding
-
and Lodging in Hostels IX
ADMISSION No. of Seats sanctioned
60 / 2008-09
with the year of approval Number
of
students Category
admitted
under
2006-07 12
01
13
categories each year in the SC & ST
05
17
17
last three years.
BC
11
12
20
OC TOTAL
32 60
21 51
07 57
Number
of
various Management quota
2007-08 2008-09
applications
received during last two
NO OF APPLICATIONS RECEIVED-13
24
years for admission under Management
Quota
ADMITTED-13
and
number admitted. X
ADMISSION PROCEDURE Mention the admission test
EAMCET
being followed, name and
Convener JNTU Campus, Masabtank, Hydrabad.
address of the Test Agency
www.eamcet.gov.in
and its URL (Website) Number of seats allotted to different
Test
candidates (AIEEE
48
Qualified separately
/
CET)
(State
conducted test/ University tests)
/
Association
conducted tests) Calendar
for
admission
against management seats : Last date for request for As fixed by the Convener of EAMCET of A.P. applications Last date for submission of As fixed by the Convener of EAMCET of A.P. application Dates for announcing final As fixed by the Convener of EAMCET of A.P. result Release of admission list As fixed by the Convener of EAMCET of A.P. (main list and waiting list should be announced on the same day) Date for acceptance by the As fixed by the Convener of EAMCET of A.P. candidate
(time
given
should in no case be less
25
than 15 years) Last date for closing of As fixed by the Convener of EAMCET of A.P. admission
26
Starting of the Academic As session
Directed
by
Acharya
Nagarjuna
University,
GUNTUR.
The waiting list should be On Expiry of main list date. activated only on the expiry of date of main list.
The policy of refund of the Complete Refund fee, in case of withdrawal, should be clearly notified. XI.
CRITERIA
AND
WEIGHTAGES
FOR
ADMISSION Describe each criteria with As fixed by the Convener of EAMCET its respective weightage i.e., Admission Test, marks in qualifying examination etc., Mention the minimum level As fixed by the Convener of EAMCET of acceptance, if any Mention the cut-off level of As fixed by the Convener of EAMCET percents & percentile scores of the candidates in the admission test for the last three years. Display marks scored in Will be displayed by the Convener of EAMCET Test etc. and in aggregate for all candidates who were admitted.
27
XII
APPLICATION FORM Downloadable form,
application Soon be kept on the Web.
with
online
submission possibilities XIII
LIST OF APPLICANTS List of candidates whose Singam Reddy Nagaiah-90.6% applications
have
received
along
percentile
/
score
each
for
been
Nalluri Yamini-78.0%
with
percentage of
Garlapati Hema-68.0%
the Jalasuthrapu Satish Kumar-62.1%
qualifying examination in
Arikatala Veerabhadra rao-71.0%
separate categories for open seats.
List of candidates
Ramesh Parikala-59.3%
who have applied along Akumalla Yalla reddy-59.6% with
percentage
percentile
and
score
Aravapalli n venkata lakshmi harika-51.8%
for
Management quota seats.
Kesari Narsi Reddy-56.5% Alla Manikanta Reddy-50.0% Kesari Srinivasa Reddy-63.5% Pullaladevi Venkateswarlu-62.6% Indela Nirosha-59.1%
XIV
RESULTS ADMISSION
OF UNDER
Admitted - 13 Vacant
- 02
MANGEMENT SEATS / VACANT SEATS Composition of selection Principal, Secretary & One Pharmacy Professional team for admission under Management Quota with the brief profile of members
28
(This information be made available
in
the
public
domain after the admission process is over) Score
of
candidates
the
individual Singam Reddy Nagaiah-90.6% admitted
Nalluri Yamini-78.0%
arranged in order of merit. Arikatala Veerabhadra rao-71.0% Garlapati Hema-68.0% Kesari Srinivasa Reddy-63.5% Pullaladevi Venkateswarlu-62.6% Jalasuthrapu Satish Kumar-62.1% Akumalla Yalla reddy-59.6% Ramesh Parikala-59.3% Indela Nirosha-59.1% Kesari Narsi Reddy-56.5% Aravapalli n venkata lakshmi harika-51.8% Alla Manikanta Reddy-50.0% List of candidates in order Singam Reddy Nagaiah-90.6% of merit to be operative
Nalluri Yamini-78.0%
from the last date of joining of the first list candidates.
Arikatala Veerabhadra rao-71.0% Garlapati Hema-68.0% Kesari Srinivasa Reddy-63.5% Pullaladevi Venkateswarlu-62.6% Jalasuthrapu Satish Kumar-62.1%
29
Akumalla Yalla reddy-59.6% Ramesh Parikala-59.3% Indela Nirosha-59.1% Kesari Narsi Reddy-56.5% Aravapalli n venkata lakshmi harika-51.8% Alla Manikanta Reddy-50.0%
List of the candidates who Singam Reddy Nagaiah-90.6% joined
within
the
date,
Nalluri Yamini-78.0%
vacancy position in each category before operation of waiting list.
Arikatala Veerabhadra rao-71.0% Garlapati Hema-68.0% Kesari Srinivasa Reddy-63.5% Pullaladevi Venkateswarlu-62.6% Jalasuthrapu Satish Kumar-62.1% Akumalla Yalla reddy-59.6% Ramesh Parikala-59.3% Indela Nirosha-59.1% Kesari Narsi Reddy-56.5% Aravapalli n venkata lakshmi harika-51.8% Alla Manikanta Reddy-50.0%
XV.
INFORMATION
ON
INFRASTRUCTURE AND OTHER
RESOURCES
AVAILABLE : Library
30
Number of Library books / Nearly 540 Titles & 29856Volumes. Titles / Journals available (program-wise) List of on-line National /
Advanced biotech Asian Journals of Pharmaceutics International Journals Indian drug review subscribed. Indian drugs Indian journal of hospital pharmacy Indian journal of natural products Indian journal of pharmacology Journal of pharmaceutical education Modern pharmaceuticals Pharma times Asian Journal Winning Today Medicine update Biology today Competition Refresher The Indian Pharmacist Chemistry Today Current Science Chemical weekly American Journal of pharmaceutical Education Pharmaceutical Processing Pharmaceutical Technology Screen Trend Drug Discovery E-Library facilities Management will try to provide LABORATORY For each Laboratory List of Major Equipment /
Pharm Chemistry –I & II
Facilities OVEN
1
CENTRIFUSE
1
HELMET
1
MECHANICAL STIRRORS
2
MAGNETIC STIRRORS
2
31
METING POINT APPARATUS
2
ELECTRIACAL WATER BATH
1
HEATING MANTLES
2
KIPS APPARATUS
1
DESICCATORS (BIG)
3
DESICCATORS (SMALL)
2
DEMINARALISER
1
INDICATOR BALANCE
11
CHEMICAL BALANCE
1
INCUBATOR
4
MICROPIPETTES
1
FRACTIONATING COLUMN
1
ELECTRONIC SINGLE PAN BALANCE 1 VACCUM PUMP
1
PH-METER
1
GLASS WARE AIR CONDENSOR
10
WATER CONDENSOR
10
SEPERATING FUNNELS
10
ROUND BOTTOM FLASKS
20
BOILING TUBES
50
BURETTE STANDS TRIPOD STANDS
7 20
32
TEST TUBES
200
DROPPER BOTTLES
17
FUNNELS
17
REAGENT BOTTLES (BIG)
48
REAGENT BOTTLES (SMALL)
24
HOLDERS
23
WATCH GLASSES
36
VOLUMETRIC FLASK
5
MEASURING CYLINDERS 250ml
05
MEASURING CYLINDERS 25ml
20
MEASURING CYLINDERS 10ml
15
PIPETTES
10ml(g)
15
PIPETTES
5 ml (g)
15
TEST TUBE STAND
40
BEAKES 250 ml
25
BREAKS 500ml
20
BREAKS 1 Lit.
10
PIPETTE STANDS
15
BURNERS
20
PHARMACEUTICS –1 HOT AIR OVEN
2
INCUBATOR
1
DISPENSING BALANCE
13
33
CHEMICAL BALANCE
2
TOP LOADING BALANCE
1
STAINLESS STEEL PERCOLATOS
25
TINCTURE PRESSERS
2
GRANULATING SIEVES
21 (5 DIFFERENT SIZE)
STANDARD SIEVES
12
(10,22,44,85,120,200 TEACH NO-2) STILL FOR WATER INJECTION
1
SINTERED GLASS FILTERS (3,4,5 EACH –10) 30 AUTO CLAVES (SMALL)
2
VERTICAL AUTO CLAVE (OR) LARGE
1
MECHANICAL STIRRERS
5
SUPPOSITORY MOULDS
30
(4, 6,12 HOLES EACH – 10) COMPOUND
MICROSCOPES
WITH
STAGE & OIL IMMERSION LENCES
MOVING 8
CLARITY TEST APPARATUS
1
MILLIPORE FILTER HOLDERS
1
MILLIPORE MEMBRANE (100 PAPERS)
1
AMPOULE FILLING & SEALING DEVICE 1 STAGE & EYE PIECE MICROMETERS
5
TABLET HARDNESS TERTERS
2
(MONSANTO & PFIZER TYPE)
34
DISSOLUTION RATE TEST APPARATUS
1
DISINTEGRATION TEST APPARATUS
1
FRIABILITY TEST EQUIPMENT
1
VERNIER CALLIPER
3
SCREW GUAGE
1
MAGNETIC STIRROR WITH HOT PLATE
3
THERMO STATIC WATER BATH
1
BRENZER BALANCE
1
CENTRIFUGE
1
OINTMEMT SPATULAS
30
MORTAR & PESTLES (PORCELIAN) BIG 10 MORTAR & PESTLES (PORCELIAN) SMALL 4 MORTAR & PESTLES GLASS (SMALL)
10
GLASS BEAKERS (1000 ml)
1
GLASS BEAKERS (500ml)
12
GLASS BEAKERS (100 ml)
2
FUNNELS (PLASTIC)
6
FUNNELS (GLASS) BIG
4
FUNNELS (GLASS) SMALL
4
MEASURING CYLINDERS (25ml)
4
MEASURING CYLINDERS (10ml)
4
MEASURING CYLINDERS (100ml) TRIPOD STANDS
4 6
35
DESICATORS
3
BURNERS
30
PHYSICAL PHARMACY & PHARMA BIOLOGY HOT AIR OVER
1
HAIR DRYER
1
CALORY METER
1
POLORI METER
1
CONDUCRO METER
1
ROTATIONAL VISCOMETER
1
PH METER
1
MOLECULAR
WEIGHT
DETERMINATION
APPARATY
1
THERMOSTATIC WATER BATH
1
CHEMICAL BALANCE
2
OSTWARD VISCOMETER
32
STALIGNO METER
1
DISCOLUTION RATE TEST APPARATY 1 STOP WATCHES
10
CENTRIFUGE (ELECTRICAL)
1
DESICATORS MICRO SCOPES WATER STILL
2 21 1
PERMANENT SLIDES FOR BIOLOGY
20
36
CHARTS
7
PAPET & GEL ELECTROPHOROSIS APPARATY BURET STANDS WITH CLAMPS
21
DISECTION MICROSCOPES
25
BURENTS
27
FUNNELS
20
MEASURING CYLINDERS (100ml)
17
MEASURING CYLINDERS (25 ml)
5
VOLUMETRIC FLASKS CONICAL FLASKS
40
(500 ML)
9
BEAKER 1 LIT.
4
BEAKERS 100ML
30
GAS CYLINDER
1
BUNSEN BURNERS
14
PHARM ANALYSIS & INORGANIC (CHEMISTRY) TBT AIR OVEN
1
IR MOISTIRE BALANCE
1
MELTING POINT APPARATUS
2
TLC KIT
1
U.V. DETECTION CABINET
1
PH METER
1
CALORIC METER
1
37
1
FLAME PHOTO METER
1
U.V. VISIBLE SPECTRO PHOTO METER 1 KARL FISHER TITRI METER
1
CHEMICAL BALANCES
5
POLORI METER
1
VORTEX MIXER
1
MICRO SCOPE
3
DISTILL WATER STILL
1
CENTRIFUGE ELECTRICAL
1
GLASS WARE BURNTS PIPETS 25ml
13 BULB
10
PIPETS 10ml
5
PIPETS 5ml
5
CONICAL FLASK 500 ml
10
CONICAL FLASK 250 ml
5
MEASURING CYLINDERS 1000ml 1 MEASURING CYLINDERS 250ml 5 MEASURING CYLINDERS 100ml 8 MEASURING CYLINDERS 10ml 5 VOLUMETRIC FLASKS
100 ml
7
VOLUMETRIC FLASKS
250ml
12
38
BEAKERS
250ml
12
DROPPER BOTTLES
13
REAGENT BOTTLES 250ml
83
REAGENT BOTTLES 150ml
2
PLASTIC FUNNELS
12
BURETTE STANDS
18
BUNSEN BURNERS
32
GAS CYLINDER
1
WATCH GLASSES
40
MICROBIOLOGY LAMINAR AIR FLOW UNIT (HORIJONTAL) MICROSCOPES WITH MOVING STAGE 10 COLONY COUNTER 01 ANTIBIOTIC ZONE READER 01 AND OIL IMMERSION LENSES AUTOCLAVES 02 INCUBATORS 02 HOT AIR OVENS 02 GAS CYLINDER 01 MECHANICAL STIRRER 03 CHEMICAL BALANCES 10
1
GLASS WARE PETRIPLATES BOILING TUBES TEST TUBES INNOCULATION NEEDLES PIPPETS 10ML PIPPETS 5ML PIPPETS 1ML COVET SLIPS CAVITY SLIDES GLASS SLIDES REAGENT BOTTLES CONICAL FLASKS 100ML CONICAL FLASKS 250ML REFRIGIRATOR
50 50 100 30 25 20 20 10 BOXES 5 BOXES 5 BOXES 20 50 50 1
39
BEAKERS 100ML BEAKERS 250ML MEASURING CYLINDERS MEASURING CYLINDERS MEASURING CYLINDERS MEASURING CYLINDERS WATCH GLASEES
20 20 10ML 10 50ML 10 100ML 10 1 LIT 02 50
BIOCHEMISTRY CETRIFUGES 01 MICROSCOPES WITH OIL IMMERSSION 10 U.V SPECTROPHOTO METER 01 GLASS SLIDES 05 BOXES TEST TUBES 50 CONICAL FLASKS 100ML 50 CONICAL FLASKS 25 50 BEAKERS 100ML 20 BEAKERS 250ML 20 MEASURING CYLINDERS 10ML 10 MEASURING CYLINDERS 50ML 10 MEASURING CYLINDERS 100ML 10 MEASURING CYLINDERS 1 LIT 02 BURETS 30 BURET STANDS 30 VOLUMETRIV FLASKS 10 BIOCHEMICAL REAGENTS FOR ANLYSIS OF NORMAL AND PATHOLOGICAL CONSTITUENTS OF URINE AND BLOOD AND FAECES (ADEQUATE)
ANOTOMY AND PHYSIOLOGY HEAMOGLOBINO METER HEAMOCYTOMETER ESR TUBES ESR STANDS ORGAN BATHS FROG BOARDS WRITING LIVERS AERATION TUBES SPIGNOMANOMETERS STETHO SCOPES FIRST AID EQIPMENTS DISSECTING BOX KYMOGRAPH PAPER CHARTS HUMAN SKELITON STOP WATCHES MISC. ITEMS
02 10 10 10 05 10 10 10 05 05 05 10
10
PHARMA ENGINEERING DRAWING BOARDS REQUIRED MODELS
20
40
COMPUTING
40 P4 Systems connected to IBM Server
FACILITIES Number and Configuration
40 - P4
of Systems Total number of systems
40
connected by LAN Total number of systems
NIL
connected to WAN Internet bandwidth
NIL
Major software packages Windows 98 SE, MS- office-2000 professional, windows available
xp professional, Tally 7.3, Page maker, Photoshop, dbase III.
Special purpose facilities EDUCATIONAL SOFTWARE ON CHEMISTRY IS available
AVAILABLE
Games and Sports Facilities
PLAYGROUND
PROVIDED
WITH
TENNIES
VOLLEYBALL & SHUTTLE COURT, Extra Curriculum Activities Soft
Skill
Development AVAILABLE
Facilities Number of Classrooms and FOUR CLASS ROOMS size of each
93.03 SQ.M
41
Number of laboratories and Department of Chemistry size of each
Lab – 1
93.00
Medicinal Chemistry – I Chemistry of Natural Products Lab – 2
77.00
Organic Chemistry – I & II Lab – 3 Inorganic Chemistry & Bio-Chemistry
77.00
Balance Room
29.00
Preparation Room
50.00
Total
326.00
Department of Pharmaceutics Lab – 1
77.00
Pharmaceutics II & cosmetics Lab - 2
77.00
Pharmaceutical Engineering – I & II Lab – 3
77.00
DHAP, Pharmaceutics – I Lab – 4
77.00
Physical Pharmacy – I & II Lab – 5
93.00
Bio-technology & Microbiology Asceptic Room
50.00
Machine Room
77.00
Total
528.00
42
Department of Analysis Lab – 1
77.00
Pharmaceutical Analysis – I Lab – 2 Pharmaceutical
77.00 Analysis
–
II
&
Biopharmaceutics Instrumentation Room
50.00
Total
204.00
Department of Pharmacognosy Lab – 1 Pharmacognosy – I & Biology
75.00
Lab – 2 Pharmacognosy – II & APH Total Department of Pharmacology
75.00
Lab – 1
75.00
150.00
Pharmacology – II 50.00 Animal House Lab-2
77.00
Aph and biology Total
202.00
Computer & English Language Lab
77.00
Number of Tutorial Rooms 3 and size of each Number
of
150SQ.M Computer ONE
Centres with capacity of each Central
WITH 40 COMPUTERS Examination ONE ROOM
43
Facility, Number of rooms AVAILABLE FOR 60 STUDENTS and capacity of each. Curricular and Syllabi for
I- B.PHARM
each of the programs as approved by the University.
T 1.1 A BIOLOGY Living and non-living and their main features, differences between plants and animals – plant and animal cell structures, cell inclusions and cell divisions – mitosis and meiosis. A brief study of the leading sub divisions of the plant kinds thallopytes, brophytes, gymnosperms and angiosperms with examples. Structure, physiology and life history of bacteria and yeast. General morphology of root, stem, leaf, flower and fruit – Different kinds of fissues – anatomical structure of a root stem and leaf. Very brief account of pillination, fertilization, fruit and seed formation. Fruit and seed dispersal. Taxonomy A systematic study of the following families : Announaceae, solanceae, liliaceae, Umbelliferae Plant Physicology: A brief study of (i) Transpiration (ii) Photosynthesis and (iii) Respiration. The Animal kingdom, outline classification with salient features and examples of each phylum. The structure life history and physiology of Amoeba paramecium, cockroach & Mosquito. Classification of Choroata, comparative anatomy of the vertebrate series of animals with special reference to cardiovascular and nervous system. Principles of the hgistology of animal fissues. Parasitology introduction to the more important protozoan and helmitnth parasites in man and domesticated animals. Outline of the life history of plasmodium, Trypanasoma and round worm.
44
PRACTICALS :1. Care anduse of the Microscope 2. Technical description of plants belonging to the Angiosperms families prescribed in the syllabus and referring them to their respective families. 3. Microscopic study of different tissues and the primary anatomical structure of a root, stem and leaf. 4. Microscopic and macroscopic examination and identification of the types prescribed in the syllabus 5. Preparation of herbarium sheets. 6. Experiments in Zoology based on Theory. T. 1.1 B MATHEMATICS ALGEBRA :- Arithmetic Progression – Geometric Progression – Permutations and combinations – Binomical theorem – Partial fractions Matrices – Determinats – Applications of determinates to solve simultaneous equations (Cramer’s rule) TRIGONOMETRY :- Trigonometric ratios and the relations between them. Sin (A+B), Cos (A+B) Tan (A+B) formulae only. Trigonometric ratios of multiple angles- Heights and distances (simple problems thereon) CO-ORDINATE GEOMETRY :- Distance between two points-Area of a triangle Co-ordinates of a point dividing a given segment in a given ratio – locus equations to a straight line in different form – Angle between straing lines – point of intersection. Differential Calculus : Continuity and limit : Differentiation, derivability and derivative, R.H. derivatives and L.H. derivatives, Differentiation General theorems of derivation. Derivatives of trigonometric functions (excluding inverse trigonometric and hyperbolic functions) Logarithmic differentiation. Partial differentiation maxima and
45
minima (elementary) Integral Calculus : Integration as inverse process of differentiation definaite integrate integration by substitution, integration by parts integration of algebraic function of ex Evaluation of area in simple cases. Differential equations : Formation of a differential equation, order and degree, derivation of a differential equation. Introduction to Laplace transforms and their use. T1.2 PHARMACEUTICAL (INOGANIC)
CHEMISTRY-1
A review of electronic structure of atom and periodic classification and group properties of elements An outline of methods of preparation and test for purity (including limits test) of the following classes of inorganic compounds included in the pharmacopoeia of India. The discussion of assays shall be excluded. 1. Acids and Bases, Buffers and Pharmaceutical aids, antioxidants, water. 2. Gastro – Intestinal agents , acidifying agents, antacids, protectives and adsorbents. Saline cathartcs. 3. Major intra and extra cellular electrolytes. Major physiologicalions Eletrolytes used for replacement therapy. Physiological acid – base balance. Electrolytes used in acid base therapy. Electrolytic combination therapy. 4. Essential and trace elements. Transition elements and their compounds. Iron and Haematinics. Mineral supplements. 5. Inorganic pharmaceuticals used for systemic effects. Drugs used primarily for cationic components. Drugs used primarily for anionic components. 6. Topical agents : Oxygen therapy. Antimicrobiasl and Astringents.
46
7. Gases and vapours. Oxygen therapy. Anaesthetic gases. Respiratory stimulants. 8. Dental products. dentifrices.
Anticarries
agents
and
9. Complexation and chelation. 10. Radio pharmaceuticals. Nuclear decomposition. Biological application of radio active drugs. Radio-opaques. 11. Miscellaneous inorganic pharmaceutical agents. Sclerosing agents Cathartics and enemas. Eperctorants and emetics. Poisons and antidotes. Sedative. P1.2 PRACTICALS : 1.
Systematic qualitative analysis of inorganic compounds containing up to 4 radicals.
2.
Preparation compounds.
of
inorganic
pharmaceutical
3. Limit tests and tests for impurities 4. Assay of inorganic pharmaceuticals. T1.3 PHARMACEUTICAL (ORGANIC-I)
CHEMISTRY
The subject of Organic Chemistry will be treated in its modern perspective keeping for the sake of convenience of the usual classification of Organic compounds but laying emphasis on the following aspects: Structure and properties: Energy of activation, Transition state; Free-radical substitution; cycloalkanes; Nucleophilic aliphatic substitution, carbocations; Elimination; Electrophilic and Freeradical addition; Conjugation and Resonance; Nucleophilic addition and Nucleophilic acyl substitution. Chemistry of aliphatic compounds, including preparation and reactions of alk-enes, alkynes, alkylhalides, alcohols, ethers, aldehydes, ke-tones, carboxylic acids and esters.
47
-II
P1.3 1.
PRACTICALS: Organic Chemistry Laboratory Techniques. (a)
Filtration Techniques.
(b) Determination of Boiling point & Melting point (c)
Crystallization Techniques.
2. Experiments in simple qualitative analysis including prepara tion of derivatives. (Monofunctional and water insoluble com pounds should be given.) 3.
Preparation of simple organic illustrating different techniques.
compounds
T 1.4 PHYSICAL PHARMACY -1 Intermolecular forces and States of matter; Binding forces between molecules, the states of matter, the Gaseous state, the liquid state, solids and the Crystalline state, Phase equilibria and the phase rule. Thermodynamics: The first law of thermodynamics, Thermo-chemistry. The second law of thermodynamics. The third law of thermodynamics Free energy functions and applications. Some physical properties of Drug Molecules : Dielectric con-stant Induced polarization, Dipole moment, Refractive Index and Molar Refraction, Optical Rotation, Optical Rotatory Dispersion. Solutions : Concentration expressions, solutions of nonelec-trolytes, ideal and real solutions, colligative properties, molecular weight determinations. Solutions of Electrolytes : Properties of solutions of electrolytes, The Arrhenius theory of electrolytic dissociation, The modern theory of strong electrolytes and other coefficients for expressing colligative properties. Ionic equilibria : Modern theories of acids, bases and salts, Sorensen's P H scale, Species concentration as a function of PH, Calculation of PH. Graphical solution of
48
PH problems, acidity constants. Buffers and Buffered Isotonic Systems; The Buffer Equation, Buffer capacity, Buffers in pharmaceutical and Biological systems, Buffered isotonic solutions, methods of adjusting tonic-ity and PH. lectromotive Force and Oxidation - Reduction systems: Electrochemical cells, Electrometric determination of PH and re-dox. Viscosity : Viscosity, Poisseulli's formula for liquids. Experimental determination of viscosity, Ostwald viscometer. Comparison of viscosities. P1.4 Practicals : T 1.5 PHARMACEUTICS -1 1.
History of Pharmacy : Pharmacy Profession, Pharmacy as a career, Evolution of Pharmacy Pharmacopoeia of India and other countries, B.P., B.P.C., U.S.P. Metrology : Systems of Weights and Measures Metric and Imperial systems - Percentage calculations and adjustment of products Interconversions - Use of alligation method in calculations - Isotonic solutions and proof spirits Weighing -Selection and care of Weights and balances.
2.
Packaging and Labelling of Pharmaceuticals : Desirable features of a container - Types of containers - Study of glass and plastics as materials for containers and rubber as a material for closures their merits and demerits - Labelling requirements. 3. Introduction to Dosage Forms - Classification Types with examples, Definitions and essential characteristics of different dosage forms - Formulation and its purpose formulation Additives : Solvents, Vehicles for Liquids Antioxidants, Preservatives, Colouring agents, Sweetening and flavouring agents in Liquid dosage forms. 4.
Liquid oral dosage forms : Definitions, general formulation, methods of preparation, uses of official and other products in common usage of the following :
49
Solutions, Aromatic Waters, Spirits, Syrups, Elixirs, Dry Syrups, Mixtures. 5.
Monophasic Liquids for external and other uses : Definitions, general formulation, methods of preparation, uses of official and other products in common usage of the following: Lotions, Liniments, throat paints, gargles, mouthwashes, glycerins, collodions, Ear drops, Nasal drops and Sprays, Douches.
6. Biphasic liquid dosage Forms : Suspensions Definitions, Types, Ideal requirements, Formulation additives, Typical examples for oral and external use, Methods of preparation. 7. Galenicals : Study of extraction processes - Maceration Percolation and their modifications, continuous hot extraction - Their applications. Principles and methods of preparations of dry, soft and liquid extracts and tinctures of IP and BP (Latest editions). 8. Suppositories and Pessaries : Ideal requirements, different bases, Preparation methods - Typical examples, calculations involving displacement value - Packaging and supply. P1.5 PRACTICALS : Preparation of atleast 50 Pharmaceutical products. T 1.6 PHARMACEUTICAL ANALYSIS -1 1.
2.
Balances - different types and weighing. Types of analysis, obtaining sample, measurement of sample and types of pi pettes. Computation of Analytical Results : Significant num bers, sources of errors and their rectification, statistical treat ment of the data and rejection of data. Ionic equations of solutions; stoichiometric and Analytical prob lems: Determination of Normality, percentage purity, Molarity,
50
3.
4.
5.
Molality and their interconversions. Principles of volumetric and Gravimetric Analysis : Standardisation; use of primary and secondary standards. Acid base concept, common ion effect and solubility product, PH and Buffers. General Principles and theory of acidimetry, alkalimetry, Oxi dation - reduction methods, precipitation methods. An account of the indicators used in these titrajtions. Diazotisation titrations. Gravimetric methods /: Typical methods involving precipita tion, coagulation, incineration oj^digestion procedures.
6.
Complexometric Titrationr rTheory, types and application in pharmaceutical analysis. Masking and damasking and its application. 7. Non-aqueous Titrations Theory, types and application in phar maceutical analysis. 8. Determination of Moisture content and Alcohol content, Theory and methods involved. 9. Polarimetry : Theory, Instrumentation and applications. Refractometry, Theory, instrumentation (Abbes, Pulfrisch and Immersion) and applications. 10. Principles of gas analysis. P1.6 PRACTICALS: Experiments based on theory. T1.7COMPUTER APPLICATIONS STATISTICALMETHODS
AND
Introduction to computers development, computer types, characteristics, anatomy - input and out put devices and other components - computer codes and arithmetic, flow
51
chart, algorithm, languages Basic Language : Basic Programme structure, constants, variables, expressions, let, rem, stop and end statements, input / output statements, control statements, subscripted variables, functions and subprogrammes, additional statements, simple programme writing related to statistics. Introduction to DOS environment DOS usage. Fundamentals of Basic language : Basic programmes, structure, loading and Unloading, Basic interpreter, Basic alphabet, constants, variables, operators, Expressions, hirarchy of operations. Branching and looping : IF -THEN, ELSE-GO TO, ON GO TO, GO SUB, ON GO SUB, WHILE-WEND, FOR TO NEXT. Arrays: Subscribed variable, single and multiple dimensions Graphs and sound : LINE, CIRCLE, DRAW, PSET,POINT, PAINT, PUT, GET, SOUND, PLAY etc., File handling: Data files, random data files, file creation, reading random files. Introduction to dBASE III PLUS, getting started, viewing and editing data, modifying structure and file utilities, managing data base, printing reports and labels, memory variables and funtions and command files. Programmeing with dBASE III PLUS, mathematical commands and other functions multiple data base files, designing custom screens, error conditions and program debugging aids, advanced features of the dBASE IIIPLUS, applications generator, pay-roll problem, development of inventory-control package, protection and networking. Application of Computers in Pharmacy. 2. Introduction to statistics, chance variations, collection, classification, graphical and pictorial representation
52
of data, Measures of central tendency anddispersion, precision and Accuracy - Measures of error. Probability, Normal and binomial distributions, sampling distributions - standard error and Fiducial limits, t - test and chi -square test of significance Principle involved and applications. Correlation coefficient and Regression analysis Method of least squares. P1.7 PRACTICALS: Computer usage Simple program writing related to statistics. Statistical Methods : Solving problems based on theory. SYLLABUS FOR LANGUAGE LABORATORY 1
Functional and advanced grammar
2
Verbal and non-verbal skills
3
Accent modulation / pronunciation
4
Vocabulary enhancement
5
Specking / writing tasks
6
Presentation skills
7
Extempore / elocution
8
Personality development
9
Communication skills
10
Group discussions
11
Interview skills
12
Practice tests for IELTS and TOEFL
13
Reflection of perfection
14
Key to success
53
T 1.8. ENVIRONMENTAL STUDIES Module 1 : Introduction -
Definition, scope and importance Measuring and defining environment development : indicators
Module 2 : Ecosystems -
Introduction, types, characteristic features, structure and functions of Ecosystems Forest Grassland Desert Aquatic (lakes, rivers, and estuaries) Module 3 : Environment and Natural Resources Management Land resources -
Land as a resource Common property resources Land degradation Soil erosion and desertification Effects of modern agriculture, fertilizer – pesticide problems,
Forest resources -
Use and over- exploitation Mining and dams – their effects on forest and tribal people
Water resources -
Use and over – utilization of surface and ground water Floods, droughts Water logging and salinity Dams – benefits and costs Conflicts over water
54
Energy resources -
Energy needs Renewable and non- renewable energy sources Use of alternate energy sources Impact of energy use on environment
Module 4 : Bio – diversity and its conservation -
-
-
Value of bio-diversity – consumptive and productive use, social, ethical, aesthetic and option values Bio-geographical classification of India – India as a mega diversity habitat Threats to biodiversity – Hot spots, habitat loss, poaching of wildlife, loss of species, seeds, etc. Conservation of bio-diversity – In – situ and Ex-situ conservation
Module 5: Environmental pollution – Local and Global Issues – Causes, effects and control measures of -
Air pollution Indoor air pollution Water pollution Soil pollution Marine pollution Noise pollution Solid waste management, composting, vermiculture Urban and industrial wastes, recycling and re- use Nature of thermal pollution and nuclear hazards Global warming Acid Rain Ozone depletion
Module 6 : Environmental problems in India -
Drinking water, Sanitation and public
55
-
-
-
health Effects of activities on the quality of environment Urbanization Transportation Industrialization Green revolution Water scarcity and Ground Water depletion Controversies on major dams, – resettlement and rehabilitation of people: Problems and concerns Rain water harvesting, could seeding and watershed management
Module 7 : Economy and Environment -
The economy and environment interaction Economics of development, preservation and conservation Sustainability; theory and practice Limits to Growth Equitable use of resources for sustainable lifestyles Environmental Impact Assessment
Module 8 : Social Issues and the Environment -
Population growth and environment Environmental education Environmental movements Environmental Vs Development
Module 9 : Institutions and Governance -
Regulation by Government Monitoring and Enforcement Environmental regulation Environmental Acts
of
Water (Prevention and Control of pollution) act Air (Prevention and Control of pollution ) act Envt.Protection act
56
Will life Protection act Forest Conservation act Coastal Zone Regulations -
Institutions and policies relating to India Environmental Governance
Module 10 : International Conventions -
Stockholm Conference 1972 Earth Summit 1992 World Commission for Environmental Development (WCED)
Module 11 : Case Studies -
Chipko movement Narmada Bachao Andolan Silent Valley project Madhura Refinery and Taj Mahal Industrialization of Pattancheru Nuclear reactor at Nagarjuna Sagar Tehri Dam Relegaon Sidhi (Anna Hazare) Kolleru lake – aquaculture Florosis in Andhra Pradesh
Module 12 : Field work -
-
Visit to a local area to document and mapping environmental assets – river/forest/ grass land / hill mountain Study of local environment – common plants, insects, birds Study of simple ecosystems – pond, river, hill, slopes etc. Visits to Industries , Water treatment Plants, affluent treatment plants
II B-Pharm T 2.1 PHARMACEUTICAL CHEMISTRY-III (Organic-II) This will be in continuation of the Organic – I Course. Following the Usual style, emphasis will be placed on the
57
followingStereo Chemistry, Optical and geometric isomerism, specification of R and S Configuration. Aromaticity, Electrophilic aromatic substitution, Arenes and their derivatives; Elements of Spectroscopy and structure; Carbanions, Nucleophilic aromatic substitution; Preparation and reactions of amines and phenols; conjugate addition; polynuclear aromatic compounds-Naphthalene, Anthracene, Phenanthrene Heterocyclic compounds: systems of numbering and naming of heterocyclics commonly encountered in therapeutic agents.structure, synthesis and reaction of pyrrole, furan, thiophene , pyridine,quinoline and isoquinoline.Acquiantance ( nomenclature,numbering geometrical structure and uses) with following heterocyclic ring systems with suitable examples of medicinally important compounds – Acridine,Benzopyran,imidazole,Benzimidazole:Oxazole, IsoOxazole,thiazole,Pyridazine,Pyramidine and Phenothiazine Name Reactions: Beckmann, Fries, Schmidt rearrangements, Clemmensen reduction,Oppenauvier Oxidation,Mannich reaction,Philips reaction. Reagents used in Organic synthesis: N- Bromo sucinimide, Lead tetra acetate and lithium aluminium hydroxide T.2.2 PHARMACEUTICAL CHEMISTRY- IV ( MEDICINAL) The following topics shall be treated covering synthetic procedures of official drugs from IP/BP, uses , mode of action, structure activity relationship wherever applicable. a) Local anti disinfectants.
infective
agents,
antiseptics
and
b) Chemotherapy: sulphonamides, antibacterial agents, anti malarials, anti amoebic agents, anti trypsonomal agents, anthelmenthics, anti fungal agents, urinary
58
antiseptic, antiviral agents, antineoplastic agents and other antibiotics. c) Local anesthetics, GI drugs and diagnostic agents.
P.2.1PHARMACEUTICAL CHEMISTRY-III & IV PRACTICAL 1. Preparation of some pharmaceutically important organic compounds involving two steps 2. Qualitative analysis- binary mixtures 3. Identification tests of organic pharmaceutical substances and drugs. 4. Synthesis of few selected drugs included in the theory.
T 2.3 PHYSICAL PHARMACY –II Study of the applications of Physico-chemical Principles to Pharmacy with special reference to the following: Solubility and Distribution Phenomena, solvent, Solute interaction, Solubility of gases in liquids,Liquids in liquids,solids in liquids,distribution of solutes in immisible solvents. Introduction to phenomena of Diffusion: Ficks First Law and Second Law Complexation: Types of complexex,methods analysis,compolexation and drug action
of
Kinetics: rates and Orders of a reactions, determination of order or reaction. Influence of Temperature and other factors on reaction. Decomposition of medicinal agents. Methods and Principles of Stabilization -–Accelerated stability studies. Interfacial Phenomena: Liquid interfaces, measurement of surface and interfacial tensions, adsorption at liquid interfaces. Surface active agents, systems of HydrophileLipophile classification. Adsorption at solid interfaces. Electrical properties of interfaces Colloids and Macromolecular Systems: Types of
59
Colloidal systems, Properties of Colloidal systems, Solubilization Micromeritics: ParticleSize and size distribution, methods of determining particle size, Particle shapes and Surface area. Methods of determining surface area. Derived Properties of Powder. Rheology: Newtonian and Non-Newtonian systems. Thixotropy measurment and applications in formulations. Determination of its viscosity and its applications. Coarse dispersions: Suspensions, Emulsions and Semisolids: Suspensions,Interfacial properties and Suspended particles. settling in suspensions; Emulsions – theories of emulsification, physical stability of emulsions, preservation of emulsions, rheological properties of emulsions, suspensions and semisolids
T 2.4 PHARMACEUTICAL ENGINEERING-I 1. Introduction: fundamental concept of material and energy balances, units and dimensions: simple inter conversions of units used in engineering calculations, dimensional analysis. Definitions of stoichometry, unit operation, unit process and chemical technology, laboratory scale,pilot scale and industrial scale operations. 2. Flow of fluids: concepts of fluid statics and dynamics, construction of simple, differential and inclined manometers, Reynolds number, bernoulis theorem and definition of head friction losses, enlargement losses contraction losses, study of orifice meter, venturimeter, pilot tube an rotameter, simple problems on bernoulis theorem, friction losses and flow meters. 3. Transportation of solids: construction details , advantages and disadvantages of belt conveyors, screw conveyors and pneumatic conveyors, bucket elevators 4. Transportation of fluids: pipe standards, joint fittings, cooks, globe valve, check valve, regulating valve, pumps, piston pump, plunger pump, diaphragm
60
pump, rotary pump, single stage suction, centrifuge pump, self priming pump, performance of reciprocating and centrifugal pumps. 5. Materials of pharmaceutical plant construction: importance of materials in construction, the merits and demerits of different commonly used materials in plant construction such as iron, steel, copper, tin, alluminium, glass, rubber and plastic. Concept of corrosion, scale formation factors in forming corrosion. Methods of reducing corrosion 6. Humidity and air conditioning: definitions of humididty , relative humidity, percentage humidity , humid heat , humid volume, dew point, humidity chart, wet bulb theory, factors influencing the wet temperature, adiabatic saturartion temperature. Theoru of Air conditioning and description of equipment. Refrigeration – principle and description of equipment. 7. Mixing: solid-solid mixing- mechanism of mixers- Vtype, paddle and rotocube mixers- selection of mixermixing of viscous masses, kneading machines and ointment mills- liquid- liquid equipment, impellerstheir charecterstics. 8. Size reduction and separation: importance of size reduction, theories of size reduction, cutter mill, ball mill fluid energy mill hammer mill, colloid mill,selection of machinery. Principles of size seperation, particle size distribution- representation of screens, screening equipment, trammels, shaking and vibrating screens, gyratory screens, cyclone, air and hydralic seperator, bag filter, Cottrell precipitator, scrubber, sedimentation theory.
T 2.4 PHARMACEUTICALENGINEERING DRAWING
(PRACTICALS) A. Construction of scales, construction of curves, orthographic projections, drawing of simple machine parts such as joints, valves fittings. B. Sketching and drawing of equipement like V-type mixer, single effect evaporator, spray dryer, vaccum crystalliser, etc.
61
C. Flow sheets for the manufacture of the following with special consideration to the different unit operations involved. Aspirin, pencillin, methyl salicylate, stearic acid, gelatin, etc. T 2.5 PHARMACEUTICAL MICROBIOLOGY A. Study
of
morphology,classification
bacteria,yeasts,actinomycetes,protozoa,fungi
of and
viruses B. Preparation of media for bacteria, fungal and actinomycetes cultures C. Theory of staining,Gram,acidfast,flagella,sporestaining methods D. Different methods for isolation,purification and preservation of microbial cultures. E. Study of bacterial growth: effect of UV light, ultrasonic waves, temperature, PH, osmotic pressure, salt concentration and metal ions. An outline of theories of antimicrobial action of drugs and chemicals. F. Study of sterilization by moist heat and dry heat, Construction and operation of autoclvae, sterilization by filtration, sterilization by radiations and sterilization by gases. G. Dynamics of disinfection merits and demerits of different disinfectants,commonly used disinfectants their mechanism of action ,Evaluation of bacteriostatics and bacteriocides H. Introduction to microbiology of water, airand milkand methods of quantitative evaluation of microbial contamination. I. Principles of immunology,methods of transmission of disease carriers, vectors and reserviors and general methods of immunization against diseases J. The study of etiology, diagnosis, source of infection,
62
mode of transmission, immunization methods, prevalence and control of the following diseases: Bacillary dysentry,Diphtheria,Tuberculosis,Leprosy,cholera,sy philis,.Gonorrhoea,tetanus food Poisoing, rabies, polio, detrameophytes, malaria and amoebiasis, AIDS and hepatitis K. Fundamentals of serology: Neutralization,.Precipitation,Opsonization,agglutinati on and Complement fixation tests,ELISA. L. Mutation, Mutagens, Bacterial transformation and transduction
Conjugation,
P 2.5 PRACTICALS 1. Introduction to mictroscope,demonstration of motility 2. Staining – simple staining, gram, acidfast and negative staining techniques 3. Preparation of media,sterilization-moist and dry heat 4. Enumeration of bacteria –total & viable counts. Isolation of Pure cultures, observation of colony characteristics 5. Bacterial Growth, Efeect of temperature,heavy metals 6. Biochemical reactions – Carbohydrate fermentations,starch hydrolysis,gelatin liquefaction,liquefaction,methyl red and VogesProskauer tests and Hydrogen sulphide production 7. Morphology of yeasts and molds 8. Microbiological analysis of water 9. Determination of Rideal Walker Co-efficient P 2.2 PRACTICALS: Experiments based on the theory T.2.6 ANATOMY AND PHYSIOLOGY 1. Introduction to the anatomical terms in
63
relation to parts of the body, systems and organs. Elementary knowledge of the human skeleton. 2. Tissues of the body: properties and functions of epithelial, connective, muscular, nervous and osseous (bone) tissues. 3. General principles of memberane permeability, diffusion, transport membrane potentials, action potentials. 4. Nervous systems: neuron; synapses, ganglion, plexus, physiology of nerve impulse, neurotransmission, and reflex arc. Central nervous system(parts and functions) and autonomic nervous system. 5. cardiovascular system and blood: heart , blood vessels, cardiac cycle circulation, blood pressure and its regulation and blood.( composition and function) 6. Respiratory system: gross anatomy of respiratory passages, physiology of respiration, nervous control of respiration. 7. Digestive system: gross anatomy of elementary canal, movement of elementary canal, gastric secretions and the enzymes involved in digestion 8. Endocrine system: physiological considerations of thyroid , pancreas, pituatory, supra renal and gonads. 9. Urino genital system: general disposition of organs of excretion, physiological consideration of urine formation, output , factors controlling it. 10. Physiology of special senses, hearing, vision, smell, taste, structure and function of skin. PRACTICALS: Histology,hematology(RBC,WBC) physiological experiments on muscle nerve preparation, demonstration of measurement of blood pressure and respiratory function. Study of bones, organs. Other experiments based on theory
T.2.7 APPLIED BIOCHEMISTRY AND CLINICAL PATHOLOGY
64
1. Definition, classification, some properties and reactions of carbohydrates, lipids and proteins. diseases related to their metabolism. 2. Carbohydrate metabolism: glycolysis, glycogenolysis, gluconeogenisis, krebs cylce, direct oxidative pathway.(HMP) 3. Metabolism of proteins and amino acids: essential amino acids and nonessential amino acids, general metabolic reacations of amino acids like deamination, transamination, decarboxylation, urea cylce; metabolism of the following amino acids, glycine, phenylalanine, tyrosine, cystein, methionine, trytophan, valine and lysine 4. Metabolism of lipids essential fattyacids ,oxidation of fatty acids, ketogenisis, biosyntheis of fatty acids and cholesterol. 5. Enzymes: classification, structure, mechanism of enzyme action, properties,factors of influencing enzyme action, activators and deactivators of enzymes, competitive and non competitive inhibition with respec to drug action, coenzymes. 6. Biochemistry of important body fluids: the biochemical role of minerals, water, vitamins and harmones. A brief outline of energy and phosphate metabolism and detoxification mechanisms. 7. The principles involved and the method used in the qualitative and quantitative analysis of blood for the following constituents: glucose, urea, cholesterol, bile salts, bile pigments, creatinine, calcium, phosphates, SGPT and SGOPT. 8. The principle involved and the method used in the qualitative and quantitative analysis of urine for the following constituents: : glucose, ketone bodies, bile salts, bile pigments and albumin. 9. Introduction to pathology of blood and urine: a. lymphocytes and platelets, their role in health and disease.(b). erythrocytes , abnormal cells, their significanvce (c) abnormal constitutents of urine and their significance of disease. 2.6 PRACTICALS: experiments based on theory. 1. Qualitative reactions for carbohydrates 2. Colour rections of proteins and amino acids 3. Estimation of blood cholesterol, glucose, urea
65
creatinine. 4. Liver function tests- SGPT and SGOPT 5. Qualitative analysis of sugar, ketone bodies, bile salts, bile pigments, albumin, creatinine in clinincal urine samples. 6. Quantitative estimation of glucose and uric acid in urine. T 2.8 FORENSIC PHARMACY A. Evaluation of Pharmaceutical and drug legislation in India- Code of pharmaceutical ethics. B. Legislation to regulate the Profession of Pharmacy .The Pharmacy Act-1948 C. Legislation to regulate the import, manufacture, distribution and sale of Drugs and Cosmetics- THE Drugs and Cosmetics Act- 1940 and Drugs and Cosmetics rule-1945,as corrected up to date D. Legislation to Control the Advertisements, excise duties and price of DrugsI. The Drugs and Magic remeids(objectionable advertisement Act) II. The Medicanal and Toilet preparations(Excise Duties Act & Rules of 1956) III. Drugs(Price Control ) Order,1970,as corrected uptodate E. Legislations to control the operations regulating to dangerous drugs, poisons and opium I. Poisons Act & Rules II. The Narcotic Drugs and Psychotropic Substances Act,1985 F. Other legisations relating to pharmaceutical Industry& profession I. The Indian patents & Design Act,1970 with reference to the Drugs & pharmaceuticals only. II. Medical Termination of Pregnancy Act III. Shops & Establishments Act B.PHARMACY III / IV MEDICINAL CHEMISTRY – II
66
1
Quantitative structure activity relationship (QSAR) studies, Basic concepts of computer aided drug design, Different drug design approaches, Basic concepts of combinatorial synthesis A study of the following classes of drugs including introduction, classification, structures, general method of synthesis (if any), mechanism of action and Structure activity relation ship (SAR). Synthesis of compounds specified against each class is to be studied.
2
Drugs acting on Central nervous System: General Anaesthetics : Halothane, ketamine, Methohexital Hypnotic and Sedatives – Phenobarbital, Amylobarbitol, Pentobarbital, Cyclobarbitone calcium., Thiopental, Hexobarbital. Chlordiazepoxide, Diazepam, Alprazolam. Anti – psychotics – Promothazine, Prochlorperazline, Fluphenazine. Chlorpromazine, Haloperidol, Clozapine, Oxypentine. Anti – depressants- Amitryptaline, Doxepine, Iproniazid, Isocarboxizide, Trazodone, Fluoxetin Anti – Anxietyagents: Amitrypataline, Doxepine, Iproniazid, Isocarboxizide, Trazodone, Fluoxetin Anti – Anxietyagents: Nitrazepam, Lorazepam, Prazepam Anti –epileptics – Phenytoin, Valproic acid, Carbamazepine, Ethosuximide
3
Drugs affecting Adrenergic mechanism : Adrenergic receptors, biosynthesis of catecholamines, Chemical classification along with structures, S.A.R. of Adrenergic drugs, Adrenergic agonists, Adrenergic blockers. Synthesis of phenylephrine, ephedrine,
67
naphazoline, terbutaline, dopamine, amphetamine, phenoxybenzamine, propranolol, metaprolol, atenolol, tolazoline. 4
Drugs affecting cholinergic mechanism: Introduction, SAR, cholinergic receptors, study of cholinergic agonists, indirectly acting cholinergic agonists, cholinergic blocking gents, neuromuscular blocking agents. Synthesis of methacholine, Carbachol, Neostigmine, paralidoxime, Propantheline, Dicyclamine, tropicamide, atropine, bipyridine.
5
Cardiovascular Agents: Antianginal agents, Calcium channel blockers, Antiarrhythmic drugs, antihypertensive agents, antihyperlipidemic agents and anticoagulants. Synthesis of methyldopa, amlodipine, clonidine, hydralazine, verapamil, clofibrate, dicoumorol, warfarin
6
Hypoglycaemics: General account on pancreatic malfunctions. Chemical classification, S.A.R. of hypoglycemics, Insulin preparations, a brief account on statins Antidiabetics – Phenformin, Glipizide, Chlopropamide, Ciglitazole, including a brief account on PPAR inhibitors, Meglitinide analogues, α- glucosidase inhibitors – Acarbose, Miglitol. A brief account on thyroid and antithyroid drugs.
7
Opoid Analgesics : Classification along with structures, Mechanism of action, S.A.R. of opioid analgesics, Mixed agonists and mixed antagonists, Central and peripheral acting anti tussive agents. Structure and uses of morphine, codeine, diacetylmorphine, nalorphine, levalophan, noscapine, dextromethorphan.
8
NSAIDS (Non – steroidal anti – inflammatory agents): Introduction and types of pain and inflammation, - Aspirin, Paracetamol, Ibuprofen, mefenamic acid, Diclofenac, Piroxicam. A brief account on Cox – 2 inhibitors.
9
DIURETICS: Introduction, chemical
68
classification along with structures, mechanism of action, S.A.R., metabolism and synthesis of acetazolamide, benzthiazide, fuosemide, ethacrynic acid chlorthiazide, HydroChlorthiazide (I.P.) Amiloride. 10
Antihistaminic agents: Introduction, Histamine receptors, Biosynthesis of histamine, Study of H 1 and H2 antagonists. Chemical classification along with structures, mechanism of action, S.A.R. of antihistamines. Synthesis and metabolism of diphenhydramine, pyrilamine, Mepyramine (I.P.) Cyclizine pheninramine, promethazine, antazoline, Astimizole, Cetrizine, cimetidine
T 3.1 PHARMACEUTICAL CHEMISTRY – V (MEDICINAL – II)
Study of the following Physicochemical properties in relation to biological activity of drugs, hydrogen bonding, pH , Pka, solubility, partition coefficient, chelation, steriochemical aspects of the following classes of drugs. Adrenerigics, Cholinergics and Anticholinesterases, General Anaesthetics, Analgesics and Antipyretics, Antiussives, Steroidal and Non- Steroidal Anticonvulsant, Analeptics, Antipsychotics, Antidepressants, Antianxiety agents, Hallucinogenic agents, Muscle relaxants, Anti-Parkinsonism agents, Antispasmodics and anti-Ulcer agents. The following classes of drugs are also covered: H2 Antagonists and H1 Antagonists, Chelating agents, Hallucinogenic agents, diuretics, Antihy-pertensive agents, Coagulants and Anticoagulants, Hypoglycemic agents and Plasma Expanders. P.3.1 PRACTICALS: 1
Synthesis of few selected drugs included in the
69
theory 2
Identification tests for drugs as prescribed in I.P.
3
Assay of selected synthetic drugs.
T 3.2 PHARMACEUTICS – II (Dosage form Technology) 1
Formulation: Physical chemical and therapeutic factors involved in the formulation of dosage forms. Introduction to preformulation studies. Formulation additives in solid, semi-solid and parenteral dosage forms. A study of the principles, formulation, manufacturing process and equipment and quality control of the following dosage forms
2.
Liquid orals – Manufacture and quality control of solutions, emulsions and suspensions.
3.
Semi-solids: Ointments, creams, pastes, jellies – Definitions Ideal requirements, Types of bases, selection of base, Typical examples
4.
Solids: Powders – Types, Typical examples – Compressed tablets Types – Formulation additives, Formulation, manufacture and quality control of tablets – Examples (I.P.) Processing problems.
5.
Capsules: Hard and soft: Formulation, manufacture and their quality control.
6.
Tablet coating: Purpose – Sugar, film and enteric coating methods
7.
Parenterals: Definitions, Types, Formulation aspects, production facilities, lay out, manufacturing and quality control, Typical examples from I.P.
8.
Ophthalmic preparations: Eye ointments, Eye drops, requirements Formulation, manufacture
70
and quality control – I.P and other important products. 9.
Pharmaceutical Aerosols: Definitions, classification – formulation, propellants, pressurized packagings, applications
10.
Radiopharmaceuticals: Therapeutic diagnostic uses Production of pharmaceuticals – Care in handling
11.
Introduction to process validation in dosage form manufacture
and radio
P 3.2 PRACTICALS: Formulation and manufacture of various types of dosage froms included in theory (at least 30) T 3.3 PHARMACEUTICAL ENGINEEERING – II 1.
Flow of Heat: Concept of heat flow: Conduction through single wall, layers in series and cylinders. Natural and forced convection, temperature gradient in forced convection, concept of surface coefficient, dimensional analysis to compute surface coefficient, boiling liquids, condensing varpours, temperature drop in parallel and counter – current heat exchangers, radiation,stefan – boltzmann law. Construction, operation and application of heat exchangers, interchangers, and finned tubes.
2.
Evaporation : Theory of evaporation, heat and material balance; evaporator types : Steam jacketed kettle, horizontal, vertical tube evaporator, forced circulation evaporators, falling film and climbing film evaporators and agitated film evaporation. Capacity of multiple effect evaporators.
3.
Drying: Theory of drying, drying curves, shrinkage of materials, construction, operation and application of different dryers, atmospheric and vaccum compartment dryer, rotary dryer,
71
agitator dryer, spray dryer, freeze dryer, fluidized bed dryer. 4.
Distillation: theory of distillation of binary miscible, immiscible mixutures. Theory of rectification, azeotropic distillation, steam distillation, simple distillation, extractive and fractional distillation, and molecular distillation design of equipment for different distillation methods.
5.
Crystallization : Mier’s theory, its limitations crystal growth, nucleation, caking of crystals, material and energy balances in crystallization, construction, operation and application of batch crystallizers, agitated tank crystallizers, Swansonwalker crystallizer, krystal crystallizer and vaccum crystallizers.
6.
Filtration: Theory of filtration, filter media construction and operation of filter press, metafilter, disc filter,rotary filter. Centrifuges – Theory, equipment and applications.
7.
Extraction: Theory of extraction, flow diagram of oil – seed extraction equipment. Prodbielniak extractor, counter current extraction, leaching of solids and equipment.
P 3.3 PRACTICALS Practicals based on Pharmaceutical Engineering Theory I and II.
T 3.4 PHARMACEUTICAL BIOTECHNOLOGY 1.
Fermentation Products: 1) Screening methods for bioactive metabolites 2) Introduction to fermenter, and its accessories. 3) Manufacture of the following: Study of media, conditions. Extraction and purification of
72
i) ii) iii) iv) v) vi)
Antibiotics – Penicillin streptomycin Acids – Citric and Lactic acid. Solvents – alcohol Enzymes – Fungal diastase Vitamins – Vitamin B 12 Miscellaneous – Dextran Lactobacillus
and
and
2.
Test for sterility : Sterility testing, media, sampling, neutralization of various antimicrobial substances in dosage forms.
3.
Animal products : Insulin extraction, purification, pancreatic, pepsin, heparin and liver preparations. Blood products and plasma substitutes of I.P.
4.
Immunological products : manufacture of vaccines, sera, antitoxins and diagnostic agents official in I.P.
5.
Principles of microbiological assay of Vitamin B12 , Penicillin, streptomycin and tetracyclines, Radio Immunoassay – Principles, estimation of insulin in blood serum.
6.
Microbial conversion of steroids.
7.
Surgical dressings, ligatures and sutures and their standards: sterilization and tests for sterility.
8.
An introduction to Recombinant DNA Technology: Brief knowledge about the making of Human Insulin, Interferons. Monoclonal antibodies, synthetic vaccines and enzyme streptokinase.
P. 3.4 PRACTICALS: Practicals based on theory.
T 3.5 PHARAMACOGNOSY – I 1.
Definitions, history, scope and development of pharmacognosy. Sources of natural drugs,
73
organized and unorganized drugs. Different methods of classification of crude drugs. 2.
Cultivation, collection, processing and storage of crude drugs. Factors influencing cultivation of medicinal plants. Types of soils and fertilizers of common use. Pest management and natural pest control agents. Plant hormones and their application. Polyploidy, mutation and hybridization with reference to medicinal plants.
3.
Quality control of crude drugs : Adulteration of crude drugs and their detection by organoleptic, microscopic, physical, chemical and biological methods of evaluation.
4.
Systematic pharmacognostic study (microscopical characters, varieties, adulterants, substitutents, principle constituents and uses) of the following: i)
ii)
iii) iv)
Carbohydrates and derived products: Agar, Guar gum, Gum acacia, Honey, Isabgol, Pectin, Starch, Sterculia and Tragacanth. Lipids: Bees wax, Castor oil, Cocoa butter, Cod – liver oil, Hydnocarpus oil, Kokum butter, lard linseed Oil, Rice bran oil, shark liver oil, and wool fat. Proteins and enzymes: Gelatin, Papain, Yeast. Tannins : Arjuna, Black Catechu, Gambier Catechu
5.
Study of fibers used in Pharmacy such as Asbestos. Cotton, Glass – wool, Nylon, Polyester, Silk and Wool.
6.
An introduction to biogenesis of primary and secondary metabolites of pharmaceutical importance.
7.
Resin & Combinations : Asafetida, Balsam of Peru, Balsam of Tolu, Benzoin, Cannabis, Capsicum, Ginger, Guggul, Jalap, Myrrh, Ipodophyllum, Storax, Turmeric.
74
P 3.5 PRACTICALS : Practicals based on theory.
T 3.6 DISPENSING, HOSPITAL AND CLINICAL PHARMACY 1.
Principles of dispensing: The form of prescription – handling dispensing, pricing and refilling of prescriptions – General dispensing procedure – posolgy – calculation of doses.
2.
Principles involved and procedures adopted in the dispensing of the following (typical examples ) classes of preparations. i) Mixtures ii) Emulsions iii) Powders lotions and liniments v) ointments
iv)
3.
Incompatibility : Physical, chemical and therapeutic incompatibilities – Methods of over coming and handling of incompatible prescriptions.
4.
Hospital pharmacy – Organization, personnel location space and equipment - The Pharmacy and Therapeutics committee, Hospital Formulary, Investigational use of drugs – Developing the budget, purchasing and inventory control
5.
The pharmacy procedural manual, Drug distribution, Dispensing out-patients, in –patients and ambulatory patients – Dispensing of ancillary and controlled substances, procurement and distributions of alcohol.
6.
Manufacturing of bulk and sterile supplies, quality control in Hospital pharmacy. Drug charges in Hospitals, Drug Information Centre – Professional practices.
7.
Introduction and scope of clinical pharmacy practice – Modern dispensing aspects – Patient counseling and advice – Medication history
75
8.
Drug interactions – Mechanisms – A systematic study of drug interactions with suitable examples. Drug - food interactons, Adverse drug reactions – Drug induced diseases.
9.
Clinical Pharmacy aspects of I) Peptic ulcer, ii) Angina Pectoris iii) hypertension iv) Asthma v) Tuberculosis vi) diabetes vii) Acute renal failure viii) AIDS ix) Hepatitis x) Rheumatoid arthritis
P 3.6 PRACTICALS: 1. 2. 3. 4.
Dispensing of prescriptions based on categories covered in theory (at least 30) Preparation of transfusion fluids Sterile Supplies Exercises on the preparation of Hospital Formulary and Drug Information Centre.
T 3.7 PHARMACOLOGY – I 1
General Pharmacy and Pharmacodynamics : Factors Influencing the effect of drugs. The does – effect relationship. Introduction to L D 50, therapeutic index. General Mechanism of drug action, SAR, drug receptors, drug toxicity and drug allergy.
2
Pharmacology of autonomic nervous system : Parasympathomimetics. Parasympatholytics, sympathomimetics, sympatholytics, neuromuscular blocking agents and ganglionic blockers.
3
Pharmacology of central nervous system: Synaptic transmission in the CNS; General anesthetics, hypno-sedatives, analgesics antipyretics, anti-inflammatory agents, antiepileptics, antiparkinsonism drugs, psychopharmacological agents, CNS stimulants, hallucinogens and drugs used in gout.
4
Drugs acting on gastro – intestinal system :
76
Purgatives antidiarrhoeal drugs, Treatment of peptic ulcer, emetics and ant- emetics. 5
Local anaesthetic and Diuretics.
B.PHARMACY IV / IV T 4.1 PHARMACEUTICAL CHEMISTRY –VI (NATURAL PRODUCTS) 1
Carbohydrates : General aspects of mono, DI and polysaecharides. A knowledge of structure including stereochemistry of glucose, sucrose and lactose. Preparation and properties of methyl glycosides. A knowledge of the sources chemistry and uses of cardiac glycosides and Anthraquinone glycosides with special reference to those official in I.P.
2
Proteins: An elementary knowledge of the classification and general characteristics of proteins, amino acids and their relationship to proteins. Polypeptide and protein hormones oxytocin. Purines, uric acid, xanthine bases and nucleic acids.
3
The extraction, general composition, properties and analysis of fixed oils, fats and waxes of the Indian Pharmacopoeia.
4
Terpenes : Occurrence, General methods of isolation and classification of terpenes, monoterpenes of pharmaceutical interest. Preparation, general composition, properties, analysis of essential oils, chemistry and biological significance of Flavanoids.
5
Alkaloids: Classification, general methods of extraction and determination of chemical structure. Quantitative determination of functional groups. Determination of the structures of ephedrine, nicotine and papaverine.
6
Steroids and Hormones : Nomenclature skeleton structures of ergo sterol, cholesterol, bile acids
77
and cortisone, preparation and structures of sex hormones, interrelationship of estradiol estrone and estroil. Synthesis of progesterone, irradiation of ergosterol and preparation and properties of calciferol, Thyroid hormones. 7
Vitamins : Classification, determination of structures of thiamine, riboflavin and ascorbic acid, skeleton structures, of vitamins official in I.P. A Study of their properties, stability, and uses.
8
A general study of antibiotics, isolation or synthesis, chemistry, stability and uses of penicillins, chloramphenicol and streptomycin. General aspects of antibiotics included in I.P.
9
Lipids: Bees wax Castor oil, Cocoa butter, Codliver oil, Hydnocarpus oil, kokum butter, Lard, Linseed oil, Rice bran oil, Shark liver oil and wool fat.
P 4.1 PRACTICALS 1
Reactions of carbohydrates, glycosides, alkaloids (including xanthine alkaloids ) and sterols with a view to detect and identify the compounds.
2
Analysis of fixed oils, waxes and soaps of I.P. according to pharmacopoeial methods.
3
Analysis of essential oils, resins and balsams of I.P,
4
Analysis of formulations containing some of the above groups of drugs
T 4.2 PHARAMACEUTICS – III (Biopharmaceutics, Pharmacokinetics and New Drug Delivery Systems) Biopharmaceutics: Introduction, Definitions, Fate of drug after administration, Blood level curves, Routes of drug
78
administration, Drug absorption and disposition. Significance in product, formulation and development. Drug absorption – Structure of biological membrane, Drug transport mechanisms, factors and kinetics involved – Physico – chemical and biological factors involved in Drugs absorption – Formulations and dosage form considerations in drug absorption. Drug Dissolution: Mechanisms, Factors and Kinetics of dissolution. Dissolution rate – Significant and evaluation official methods. Bioavailability: Concept and definitions, Factors involved – Assessment and significance. Drug Distribution: Drug metabolism, Path ways of drug metabolism; Excretion – Excretion through urine, bile, farces, lungs and skin – Mechanism of Renal exvretion – Renal clearance. Pharmacokinetics: Introduction – Compartment models – Study of the methods of Estimation, significant of the following parameters: biological half –life, Apparent volume of distribution, renal clearance, total body clearance, Absorption rate, AUC – Mathematical expressions describing the variation in blood concentrations following I.V and oral routes. Introduction to dosage regimens. New Drug Delivery Systems : 1)
Sustained release dosage
79
forms: Principles and concepts Involved , dosage calculations, methods adopted in release controlling – Design, manufacture and evaluation of various types of sustained release products, implants. 2) Microencapsultaion : Purpose and applications – Techniques of Microencapsulation. 3) Introduction to Novel drug delivery systems concept of controlled drug delivery, oral and Transdermal delivery systems – Liposomes. Concepts on niosomes and resealed erythrocytes P 4.2 PRACTICALS : Experiments based on theory. Analysis of literature data toevaluate various Pharmacokinetic parameters. T 4.3 COSMETIC TECHNOLOGY INTRODUCTION : Definition of cosmetics – Classification of cosmetics An approach to the formulation, manufacture and evaluation of the following cosmetics: 1
Preparations for the face : Vanishing creams, cleansing creams cold creams.
2 Preparation for hands : lotions, liquid creams, nail
Hand creams and
lacquers and nail polish removers. 3 Body Cosmetics :Deodorants and antiper perspirants talcum and dusting powders, and bleaching preparations. 4 Preparations for the hair:Shampoos, hair creams, hair tonics, hair dyes andhair bleaches and depilatories
80
(hair removers). 5
Dental preparations : Tooth powders and pastes.
6 Shaving preparations: Pre- shave and after shave lotions, shaving creams and soaps. 7 Baby specialties :Baby powder, baby oils and lotions. 10
General aspects of cosmeticPreparations:Coloring agents in cosmetics preservatives and antioxidants and other additives in cosmetics.
P 4.3 PRACTICALS Preparation of various cosmetics studied in theory. T. 4.4 PHARAMCOGNOSY – II Systematic pharmacognostic categories of crude drugs.
studies
of
following
1
Glycosides: Aloes, Ammi, Brahmi, Buckwheat Cantharides, Cascara, Chirata, Digitalis, Dioscorea, Gentian, Ginseg, Kalmegh, liquorice, Psoralea, Quassia, Senna, Rhubarb Squill, Strophantus, Wild Cherry bark.
2
Alkaloids: Aconite, Belladonna, Cinchona. Colchicum, Datura, Duboisia, Ephedra, Ergot, Hyoscyamus, Ipecac, Kurchi, Lobelia, NuxVomica, Opium, Rauwolfia, Solanum Khasianum, Vasaka, Vinca, Withania.
3
Volatile oils : Bitter orangepeel, caraway, Cardamom, Cassia, Cinnamon, Citronella, Civet, Clove, Coriander, Dill, Eucalyptus, Fennel, Gaultheria, Lemonpeel, Musk, Nutmeg, Palmarosa, Peppermint, Saffron, Sandal Wood, Tulsi, Vetiver.
4
Historical development of Plant tissue culture; types of cultures, a study of calcus culture and cell suspension, culture, nutritional requirements, growth and their maintenance – Applications of
81
plant tissue culture in production of Pharmaceutically important secondary metabolities. 5
A study of the following Ayurvedic drugs, (Botanical source, chemical constituents. Pharmacological actions and uses) 1
Amla ( Phyllanthus embilica) 2. Bheda (Terminalia belerica) 3. Kantkari (Solanum xanthocarpum) 4 Malkangni (celactrus Panicula ) 5 Tylophera (Tylophora indica) 6 Satavar (Asparequa recomosus) 7. Bhilawa (Semicarpua Anacardium) 8 Kalijiri (Vernoniia anthelmintica ) 9 Kaner (Nerium indicum) 10 Punamava (Bocrhaevic diffuca) 11 Sankhapushpi
P 4.4 PRACTICALS : Practicals based on theory.
T 4.5 PHARMACOLOGY – II 1
Pharmacology of cardiovascular system: Cardiac glycosides, antihyper tensive drugs, coronary dilators, antihyper lipidamic drugs, antiarrhythmic drugs. Drugs acting on the blood and blood forming agents. Coagulants, Anticoagulants, haematinics – iron, Vitamin B 12, and folic acid
2
Respiratory system: Bronchodilators, antitussives and expectorants.
3
Autocoids: Histamine – Antihistaminics, Serotonin – Antagonists, Prostaglandins.
4
Chemotherapy: General principles – Sulphonamides, antibiotics antiprotozoal drugs, antimalarials, antiamoebic, antifungal and antiviral drugs, chemotherapy of tuberculosis, Leprosy and cancer.
5
Pharmacology of endocrine system: Thyroid – Anti-thyroid drugs, insulin and oral hypoglycemics, glucagon, adrenocortical steroids, Pituitary hormones, Sex hormones and oral
82
contraceptives 6
Bioassays: General principles of bioassays, Estimation of errors in bioassays. Study of the official biological assay methods of Adrenaline, Posterior pituitary hormones, insulin, Gonadotrophic hormones, Test for pyrogens.
7
Principles of Toxicology: Poisons, general treatment of poisoning, systemic antidotes, Treatment of insecticide poisoning heavy metal poisoning, Narcotic drug, barbiturate and organophosphorous poisoning, drug dependence, drug abuse, Addictive drugs and their treatment.
P 4.5 PRACTICALS: Pharmacology I and II .
Practicals
based
on
T 4.6 PHARAMACEUTICAL ANALYSIS –II General treatment of the theory, Instrumentation and applications of the following analytical methods. i) ii) iii) iv) v) vi) vii) viii) ix)
x)
Colorimetry, nephelometry and turbidimetry. Spectrophotometry – Visible, ultra – violet and infra- red Fluorimetry Flame photometry Potentiometry and PH meter. Conductometry and high frequency titrations. Polarography and amperometry. Differential Thermal Analysis. Separation techniques and other general methods used in pharmaceutical analysis as given below: a) Chromatography, introduction, paper, thin layer and column. b) Gas chromatography c) Ion –exchange chromatography and electrophoresis. d) HPLC & HPTLC e) Counter current distribution. Basic principles of Radio immune Assay
83
xi)
and it s application in Pharm. Analysis. Principles of NMR, ESR, Mass spectroscopy and X-ray diffraction analysis.
P 4.6 PRACTICALS : 1.
2.
3. 4.
T
4.7
Quantitative determinations of official drugs and pharmaceuticals by different methods methods given in theory, Chromatographic experiments by different methods to know the homogeneity of substances and separation of drugs. To determine the alcohol, and moisture in the pharmaceutical preparations and crude drugs. Dosage form Analysis and testing of market samples.
INDUSTRIAL
MANAGEMENT
AND
PHARAMACEUTICAL MARKETING 1
Elements of Organization and Management – Functions of Management.
2
Plant location and lay-out of an industry – various factors affecting locational aspect, layout of building and equipment product lay-out v/s process layout, Drug store location and selection of premises, drug store management
3
Production planning and control – Scientific purchasing , quality control, problems of productivity, stores organisation , location of store, receiving, inspection of materials, issue from the store, control of store and stocks, Store Accounting and Records.
4
Personnel Management – Selection, appointment, training, transfer, promotion, demotion policies, remuneration job evaluation, human relations.
5
Sales organization – market, definition – different approaches to the study of marketing, institutional approach. Market Planning – Product Planning
84
method of marketing, wholesale retailers, functional approach, cost and efficiency in marketing commodity approach. 6
Distribution policies – Pharmaceutical Product Marketing Sales promotion policies – detailing to Physician, professional persons, sampling, window and interior display, product advertising, sales promotion, publicity.
7
Elementary industrial Accountancy: Elements of double entry book – keeping, Books of accounts – journal and ledger, cash book Balance sheet, Profit and Loss Account. Principles of Costing and Estimating.
8
Regulatory Affairs: a) Schedule M. of Drugs and cosmetics act B) Drug Development stages – NDA and ANDA filing C) ICH guideline.
Academic Calendar of the Commencement of classes 09-10-2006 First sessional examinations 15-12-06 to 23-12-2006 University. Pongal vacation 10-01-07 to 17-01-2007 Second sessional examinations 05-03-07 to 13-03-07 Summer vacation 01-05-07 to 31-05-07 Third sessional examinations 11-06-2007 to 19-06-2007 Closing of the class work 28-06-2007 Preparation holidays 29-06-2007 to10-07-2007 Commencement of annual 16-07-2007 exams(theory)
85
Academic Time Table.
86
Teaching Load of each Faculty
Internal Evaluation
HOURS
L1 (FT) L2(FT) L3(FT) L4(FT)
6 12 12 12
L5(FT)
18
L6(FT)
18
L7(FT)
17
L8(FT)
18
L9(FT)
18
L10(FT)
18
L11(FT)
17
L12(FT)
17
L13(FT)
17
L14(FT)
18
L15(FT)
18
L16(FT)
18
L17(PT)
2
L18(PT)
5
L19(PT)
5
Continuous 3 Mid sessional examinations conducted by the college system
and for theory subjects and one practical examination at the
place Student’s
LECTURER
end of the year. assessment
of Through feed back from the students in students and staff
Faculty, System in place.
meetings.
For each Post Graduate program give the following details i. Title of the program ii. Curricula and Syllabi iii. Faculty Profile.
S.No.
Name
Designation
Subject
Teaching
87
Brief Profile of each faculty
-NA-
Laboratory
-NA-
exclusive
facilities to
the
PG
Program Special Purpose
-NA-
Software, all design tools in
-NA-
case Academic
calendar
and
-NA-
frame work Research focus
-NA-
List of typical research projects Industry Linkage
-NA-
Publication (if any) out of
-NA-
research in last three years out of masters projects Placement status
-NA-
Admission procedure
-NA-
Fee Structure
`
Hostel Facilities Contact Coordinator
-NA-
address of
-NA-
the
of
-NA-
PG
Program
Name
-NA-
Address
-NA-
Telephone
-NA-
E-Mail
-NA-
NOTE:
88
