First European Congress on Magnesium, Lisbon, October 6-8, 1983

Magnesium Deficiency Physiopathology and Treatment Implications

Editors M.J. Halpern, Lisbon /. Durlach, Paris

42 figures and 57 tables, 1985

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Contents

I. Biochemistry and Physiologic Functions Halpern, M.J. (Lisbon): Magnesium Physiopathology. I. Normal Physiology and Biochemistry Halpern, M.J. (Lisbon): Magnesium Physiopathology. II. Magnesium Deficiency and Depletion Classen, H.G.; Fischer, G.; Dobler, L.; Guigas, C ; Herold, B.; Hirneth, H.; Jacob, R.; Rieg, C.T. (Stuttgart): Modification of Acute Stress Reactions by the Actual Magnesium Status and Synthetic Calcium Antagonists Bara, M.; Guiet-Bara, A.; Durlach, J. (Paris): Comparative Study of the Effects of Magnesium and Taurine on Electrical Parameters of Natural and Artificial Membranes. Action on Electrical Constants of Epithelial Amniotic Cell Membranes Guiet-Bara, A.; Bara, M.; Durlach, J. (Paris): Magnesium: A Competitive Inhibitor of Lead. Study on the Isolated Human Amnion Durlach, J.; Rapin, J.R.; le Poncin-Lafitte, M.; Rayssiguier, Y.; Bara, M.; GuietBara, A. (Paris/Theix, Beaumont): 3H-Taurine Distribution in Various Organs of Magnesium-Deficient Adult Rats Steidl, L.; Kasparek, J.; Kubicek, R. (Olomouc): Seasons of the Year and the Tetanic Syndrome. Magnesium and Zinc Metabolism Vormann, J.; Gunther, T. (Berlin): Fetal and Maternal Magnesium Metabolism. Fetal Development, Effect of Mg Deficiency and Isoproterenol Gunther, T.; Vormann, J. (Berlin): Regulation of Intracellular Mg2+ by Mg2+ Efflux Pointillart, A. (Jouy-en-Josas): Magnesium Metabolism in the Growing Pig

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II. Measurement of Magnesium Levels Rousselet, F.; Cherruau, B.; Granier, M.H. (Paris): Methods for Measuring Magnesium in Biological Samples

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Contents Alda, J.O.; Soteras, F.; Escanero, J.F. (Zaragoza): Magnesium Bound to Human Serum Proteins Determined by Dialysis and Ultrafiltration Techniques. Effects of pH and Temperature

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III. Cardiovascular Disease Durlach, J.; Henrotte, J.G.; Lepage, V.; Elchidial, A.; Degos, L. (Paris): HLABw35 Antigen, Mitral Valve Prolapse and Blood Magnesium Level Durlach, J.; Lutfalla, G.; Poenaru, S.; Reba, A.; Henrotte, J.G.; Fabiani, F.; Vernejoul, F. de (Paris/Neuilly-sur-Seine): Latent Tetany and Mitral Valve Prolapse due to Chronic Primary Magnesium Deficit Jeresaty, R.M. (Hartford, Conn.): Prognosis of Idiopathic Mitral Valve Prolapse. Does Mitral Valve Prolapse Constitute a Risk Factor? Galland, L. (New Haven, Conn.): Magnesium Deficiency in Mitral Valve Prolapse Fernandes, J.S.; Pereira, T.; Alcazar, A.; Franca, A.; Andrade, R.; Pereira, J.N.; Pessoa, J.; Rodrigues, J.C.; Guerra, L.; Laires, M.J.; Halpern, M.J. (Lisbon): Idiopathic Mitral Valve Prolapse and the Neuromuscular Form of Primary Magnesium Deficit Rayssiguier, Y. (Theix, Ceyrat): New Data on Magnesium and Lipid Interrelationships in the Pathogenesis of Vascular Diseases Pereira, J.N.; Laires, M.J.; Franca, A.; Alcazar, A.; Andrade, R.; Rodrigues, J.C.; Jacinto, P.P.; Pereira, T.; Halpern, M.J.; Fernandes, J.S. (Lisbon): Hypomagnesemia and Coronary Ischemic Disease. Experience of a Coronary Follow-Up Service Maurat, J.P.; Stimmesse, B.; Mougin, D.; Becque, O.; Belon, J.P.; Magnin, P. (Besancon): Effects of Magnesium on Ventricular Action Potentials and Contractility in Low Extracellular Potassium Concentration and Digitoxin Intoxication Laires, M.J.; Lucilia de Mello, M.; Maia, O.; Ruas da Silva, J.; Pereira, T.; Halpern, M.J. (Lisbon/Coimbra): Hypomagnesemia in Chronic Alcoholism. Experience in a Recuperation Center Chappuis, P.; Jacqueson, A.; Ducimetiere, P.; Rousselet, F. (Paris): Magnesium, Copper and Zinc: Relationships with Ischemic Heart Disease Risk Factors .

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IV. Renal Absorption and Elimination Stanbury, S.W. (Manchester): Magnesium Metabolism in Hypoparathyroidism. A Role for Calcium in Regulating the Renal Tubular Reabsorption of Magnesium Rapado Errazti, A.; Defillo Guerrero, G.; Herrera Pombo, J.L. (Madrid): Specific Disorder of Magnesium Renal Tubular Transport in Diabetes mellitus. Its Physiological and Clinical Relevance

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Contents Melico-Silvestre, A.; Campos, M.; Guimaraes, H.; Isaac, J.; Cabral, P.; Aguiar, A.J.; Lopes, R.; Marques, A. (Coimbra): Magnesium and Dysrhythmias: Analysis by the Holter Method Campos, M.; Melico-Silvestre, A.; Cabral, P.; Marques, A. (Coimbra): Magnesium and Renal Chronic Insufficiency (Hemodialysis) Schroll, A.; Brehm, A.; Struck, E.; Mendler, N.; Richter, J.; Sebening, F. (Miinchen): Magnesium Substitution under Extreme Excretion during Extracorporeal Circulation Mountokalakis, T.; Tzouvelekis, E.; Mayopoulou-Symvoulidou, D. (Athens): Effects of Gentamycin on Renal Magnesium Excretion Mountokalakis, T.; Virvidakis, C ; Loukas, A.; Mayopoulou-Symvoulidou, D. (Athens): Changes in Renal Magnesium Excretion following Exercise in Trained Athletes Montanari, A.; Graziani, G.; Borghi, L.; Cantaluppi, A.; Simoni, I.; Elia, G.F.; Casati, S.; Novarini, A. (Parma/Milano): High Muscle Magnesium in Uremic Patients Undergoing Long-Term Dialysis Treatment

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V. Influence on Bone and Selected Bone Diseases Munzenberg, K.J.; Anders, G.; Ruhr, J.; Gebhardt, M.; Helbig, J. (Bonn-Venusberg): Crystallography of Bone Mineral under the Influence of Magnesium and Fluorine Keck, E.; West, T.B.; Schartl, A.; Peerenboom, H.; Delling, G.; Kruskemper, H.L. (Dusseldorf/Hamburg): Influence of Calcium-Regulating Hormones and Prostaglandins on Magnesium Metabolism of Human Trabecular Bone. Kiihr, J.; Munzenberg, K.J.; Anders, G.; Helbig, J. (Bonn-Venusberg): Scanning Electron Microscopy of Bone Treated with Magnesium Anders, G.; Kiihr, J.; Munzenberg, K.J.; Helbig, J. (Bonn-Venusberg): Indications and Contraindications of High Magnesium Doses in Orthopaedics . . . Soldatovic, D.; Nedeljkovic, M.; Matovic, V.; Antonijevic, N. (Belgrade): Influence of Tetracycline on the Movement of Magnesium Deposited in Bones and Teeth under the Conditions of Fluorosis Taylor, W.H. (Liverpool): Lowered Serum Magnesium Concentrations in Paget's Disease of Bone

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VI. Neurologic and Muscular Dysfunctions Poenaru, S.; Rouhani, S.; Durlach, J.; Aymard, N.; Belkahla, F.; Rayssiguier, Y. (Paris/Theix, Beaumont): Brain Tissue Monoamines in Magnesium-Deficient Rats Poenaru, S.; Rouhani, S.; Durlach, J.; Aymard, N.; Belkahla, F.; Rayssiguier, Y. (Paris/Theix, Beaumont): Correlations between Cerebral Monoamine Metabolism and Vigilance States in Experimental Magnesium Deficiency

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Contents Barthelemy, C ; Martineau, J.; Garreau, B.; Bruneau, N.; Jouve, J.; Muh, J.P.; Lelord, G. (Tours): Electrophysiological and Biochemical Effect of Oral Magnesium and Combined Magnesium + Vitamin B6 Administration in Autistic Children Popoviciu, L.; Fagarasan, M.; Nicolaescu, I.; Farkas, E.; Oprisor, I. (TirguMures): Clinical-Electroencephalographical and Polygraphical Research in Spasmophilic Hypomagnesian Syndromes Wayoff, M. (Nancy): Magnesium Deficiency and Spasmophilia in the ENT Field

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VII. Role in Various Nutritional States Vanroelen, W.; Van Rooy, P.; Van Gaal, L.; Snijders, D.; De Leeuw, I. (Antwerp): Magnesium Status during Dietary Treatment of Obesity Traba, M.L.; De la Piedra, C ; Marin, A.; Babe, M.; Rapado, A. (Madrid): Effect of Magnesium on the Synthesis and Distribution of Vitamin D Metabolites in Serum, Bone, Intestine and Kidney Velloso da Costa, A. (Brasilia): Studies of Magnesium and Calcium Excretion in a Normal Population Sample in Brazil Leszek, G.; Campo, O. del (Jacksonville, Fla.): Role of Magnesium in the Dietotherapy of Degenerative Diseases. Importance of Magnesium Supplementation of Diets of Elderly Patients Subject Index

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