Jack Bragg, DO FACOI. Associate Professor of Medicine School of Medicine University of Missouri-Columbia

Jack Bragg, DO FACOI Associate Professor of Medicine School of Medicine University of Missouri-Columbia 1 • • 2 New Treatments for Irritable B...
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Jack Bragg, DO FACOI Associate Professor of Medicine

School of Medicine University of Missouri-Columbia

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New Treatments for Irritable Bowl Syndrome, Constipation and Diarrhea

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Irritable Bowel Syndrome (IBS)

IBS is an FBD in which recurrent abdominal pain is associated with defecation or a change in bowel habits. Disordered bowel habits are typically present as are symptoms of bloating and distention.

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Learning Objectives

After participating in this educational activity the participant should be able to:  Diagnose IBS and differentiate from other bowel disorders using established clinical guidelines  Summarize the efficacy and safety of pharmacologic and non-pharmacologic treatment options for IBS  Implement patient-specific methods for managing IBS symptoms and improving function and quality of life

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Drug List Generic

Trade Name

Generic

Trade Name

Alosetron

Lotronex

Imipramine

Tofranil, Tofranil‐PM

Amitriptyline

Elavil, Endep, Vanatrip

Ispaghula

Fybogel, Ispagel

Cholestyramine

Cholestyramine Light, Prevalite, Questran, Questran Light

Linaclotide

Linzess

Citalopram

CeleXA

Loperamide

Imodium, Imodium A‐D, Kaopectate II, Maalox Anti‐Diarrheal Caplets, Pepto Diarrhea Control

Desipramine

Norpramin

Lubiprostone

Amitiza

Dicyclomine

Bentyl

Mesalamine/Mesalazine

Apriso, Asacol, Lialda, Pentasa

Diphenoxylate‐atropine

Lomotil

PEG 3350+E

Colyte, GaviLyte‐C, Golytely GlycoLax, MiraLax

Doxepin

Adapin, Silenor, Sinequan

Paroxetine

Paxil, Paxil CR, Pexeva

Elobixibat

Elobixibat

Plecanatide

Plecanatide

Eluxadoline

Eluxadoline

Prucalopride

Resolor

Fluoxetine

Prozac, Sarafem

Psyllium

Konsyl, Metamucil, Reguloid

Hyoscyamine

Anaspaz, Cystospaz, Donnamar, Levsin

Rifaximin

Xifaxan

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Expediting IBS Diagnosis in Primary Care 7

Prevalence and Impact of IBS  Worldwide prevalence: 7% to10%

 1.5 times more prevalent in women  More commonly diagnosed in patients

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