Jack Bragg, DO FACOI Associate Professor of Medicine
School of Medicine University of Missouri-Columbia
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New Treatments for Irritable Bowl Syndrome, Constipation and Diarrhea
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Irritable Bowel Syndrome (IBS)
IBS is an FBD in which recurrent abdominal pain is associated with defecation or a change in bowel habits. Disordered bowel habits are typically present as are symptoms of bloating and distention.
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Learning Objectives
After participating in this educational activity the participant should be able to: Diagnose IBS and differentiate from other bowel disorders using established clinical guidelines Summarize the efficacy and safety of pharmacologic and non-pharmacologic treatment options for IBS Implement patient-specific methods for managing IBS symptoms and improving function and quality of life
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Drug List Generic
Trade Name
Generic
Trade Name
Alosetron
Lotronex
Imipramine
Tofranil, Tofranil‐PM
Amitriptyline
Elavil, Endep, Vanatrip
Ispaghula
Fybogel, Ispagel
Cholestyramine
Cholestyramine Light, Prevalite, Questran, Questran Light
Linaclotide
Linzess
Citalopram
CeleXA
Loperamide
Imodium, Imodium A‐D, Kaopectate II, Maalox Anti‐Diarrheal Caplets, Pepto Diarrhea Control
Desipramine
Norpramin
Lubiprostone
Amitiza
Dicyclomine
Bentyl
Mesalamine/Mesalazine
Apriso, Asacol, Lialda, Pentasa
Diphenoxylate‐atropine
Lomotil
PEG 3350+E
Colyte, GaviLyte‐C, Golytely GlycoLax, MiraLax
Doxepin
Adapin, Silenor, Sinequan
Paroxetine
Paxil, Paxil CR, Pexeva
Elobixibat
Elobixibat
Plecanatide
Plecanatide
Eluxadoline
Eluxadoline
Prucalopride
Resolor
Fluoxetine
Prozac, Sarafem
Psyllium
Konsyl, Metamucil, Reguloid
Hyoscyamine
Anaspaz, Cystospaz, Donnamar, Levsin
Rifaximin
Xifaxan
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Expediting IBS Diagnosis in Primary Care 7
Prevalence and Impact of IBS Worldwide prevalence: 7% to10%
1.5 times more prevalent in women More commonly diagnosed in patients