Introduction M+W Group

M+W Group Overview M+W Group

Financials 2014

 Leading global engineering and project company for high-tech production facilities, mission critical infrastructure and energy & environmental solutions

Asia/Pacific 30.1 %

 Technical expertise for facilities and processes  More than 8.000 employees  Headquarter in Stuttgart, Germany

EMEA

42.5 %

Americas

27.4 %

Sales 2.56 bn. €

 Set-up in four regions and 32 countries

Locations Asia/Pacific 26.0 %

EMEA 45.9 %

Order Intake 3.03 bn. € Americas 28.1 %

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M+W Group Overview Organisation

Global Business Units M+W Group

Americas

APAC

Europe/ CIS

MEA

In addition to the regional set-up M+W is operating across the four regions with its global business units:  Life Science

Life Science

 Advanced Technology Facilities

Advanced Technology Facilities Energy & Environment Technologies

 Energy & Environment Technologies  Chemicals

Chemicals

 High-tech Infrastructure

High-tech Infrastructure

Scope of Services Consulting

Design

Consulting Services, Evaluation, Programming

Facilities Services / Maintenance Operation 

Maintenance of Technical Building Systems

 Commissioning



Energy Management

 Hook-up



Infrastructure Services



Commercial Services

Feasibility Studies



Preliminary Design

 Project Management



Programming



 General Contracting



Manufacturing Technology

Detail, Basic and Final Design



Permits / Environmental Compliance



Value Engineering

Site Selection

Operation

Construction Management and Build





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Planning and Design

Construction

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Competences

Field of Experiences M+W Group

Pharmaceutical Industry

Biotechnology

Chemicals and Fine Chemicals

Medical Devices

Consumer and Beauty Care

Food

• Solid dosages • Parenterals • Injectables • Lyophyllisation technology • Ointments • High potent APIs • Clean utilities • Technical facility management

• Up-streamprocessing • Down-stream processing • Vaccines • Blood plasma • Advanced therapy • Disposable technology

• Fine chemicals • API synthesis • Refineries • Power

• Stents • Surgery devices • Implants • Tissue engineering

• Beauty care • Baby care • Personal paper • Household care

• Beverages • Nutrition • Chocolate • Culinary • Dairy • Cereals • Ice cream

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M+W Group at a Glance M+W Process Industries is an Integrated Engineering Contractor Industry Competences •

Pharmaceutical Industry

•

Biotechnology Industry

•

Chemical and Fine Chemical Industry

•

Medical Devices

•

Consumer and Beauty Care

•

Food Industry

Technical Facility Management

Our Services for Investment Projects •

Engineering services

•

General planning services (EPCMV)

•

General contractor for turnkey or EPC

•

Compliance and validation

Validation Construction Design Consulting

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M+W Project Set-Up – „Local“ and Worldwide“ “Global Cooperation and Center of Excellences” CUSTOMER Requirements – “Definition of a project or activity” Local Partner

M+W Group Pharma / Building

Architect Constr.

Biotech / API Building

Partner

Chemical/ API

Automation

Automation M+W PA

Freelancer

Internal Support

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Local Projects and Organization

Local Support © M+W Group

Competence Spectrum M+W Group PROCESS TECHNOLOGY

BUILDING SERVICE SYSTEMS

Process equipment, process infrastructure (clean utilities, CIP-/SIP-systems, chemical supply), piping technology, emission control, waste water treatment, waste handling

cleanroom technology, ventilation, utilities, fire protection installation, building automation, electrical and communication systems

CIVIL, “PROCESS” ARCHITECTURE Site development, Facility optimization, master planning, FDA – cGMP study, classifications Structural works (concrete, steel), civil construction, finishes, cladding

LOGISTICS

AUTOMATION AND PROCESS CONTROL Instrumentation, process automation, manufacturing execution system (MES), vertical integration

LAB-FACILITIES

Warehouse- and storagemanagement and -control, transportation systems

Equipment and furniture

M+W has in-house capabilities for all critical disciplines ! 8

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Services

Scope of Services

Consulting

 Feasibility studies  Conceptual design  Process simulation

Engineering

• General planning or

single discipline engineering - Process technology and optimizing  Site selection studies - Logistics - Process automation  Benchmarking - Building service  EU-GMP / FDA consulting systems, HVAC  Support authority - cleanroom inspections and technology demands - Civil & architecture • Relocation planning • Integration planning

Construction

• Interdisciplinary

• • • • •

construction and project management Site management Authority engineering Procurement Turnkey project execution as general contractor Design + build on open book or GmaxP-contracts

Qualification & Validation

Technical Facility Management

• DQ / IQ / OQ • Risk analysis acc.

• Maintenance /

to FMEA or HACCP • Computer system validation (CSV) • Cleaning validation • Support services for process validation

• • • •

customer services Requalification Recalibration cleanroom measurement Contract management for maintenance services

M+W Group offers complete solutions from the one source !

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Typical Project Master Schedule Kostenschätzung ± 20% Kostenschätzung ± 10%

Consulting

Feasibility Study

Engineering

Conceptual Design

Construction

Basic + Ext. Basic Design

Qualification & Validation

Technical Facility Management

Detail Engineering Procurement

Second Opinion Value Engineering

Construction

Qualification Decision „GO“

Final Investment Decision

Handover Support Validation

Maintenance Customer Services

Start of Production 11

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Tools and capabilities

Project Management • Scope, time, cost, and quality management • Risk management Project data

• Procurement management • Project management by modern operation tools • Project-flow model (PFM) • Web based collaboration tool with access for clients • Progress reporting Abläufe Basic Engineering

Disciplines

Auftraggeber

Freigegebene Konzeptstudie

F1

F2

Projektleitung

Projektterminplan Resourcenplan

Prozeßtechnik

Detaillierung Verfahrensbeschreibung

Detaillierung BFD

Detailliertes Verfahrensfließbild

Equipmentlisten

Wärmelasten

ELT-Verbrauch

Handling Logistik

Materiallisten Lagerlisten Wiegematrizen

Beschreibung Handling/ Logistik

Handlingschema (BFD)

Auslegung Lagerbereiche Equipmentlisten

Wärmelasten

ELT-Verbrauch

Detaillierung Utilities

Utilities PFD

Equipmentlisten

Wärmelasten

ELT-Verbrauch

Utilities

Enddokumentation

Vorgabe Kostenstruktur

stat. Lasten

Abgleich Auslegung

P&ID 10%

Endgültige Bilanzen Medien/ELT

stat. Lasten

endgültige Materialbilanzen

stat. Lasten

P&ID 10%

Dimensionierung Equipment und RL

Datenblätter Ausrüstung

Dimensionierung Equipment und RL

Datenblätter Ausrüstung

Spezifikation Spezialausrüstung

Listen aus P&ID 50%

P&ID 50%

Trassenkoordinierung und Vorgaben

Detaillierte Aufstellungsplanung Prozeß/Hdl./Util.

3D-Studie kritischer Bereiche

Stahlbau Konzept

Auslegung HVAC

Utilities ELT-Lasten

Aufstellungsplan Trassenplan

PLT

Detaillierung PLT-Konzept

Abschätzung ELT-Verbrauch

PLT-Trassenbedarf

IT

Detaillierung IT-Konzept

Abschätzung ELT-Verbrauch

IT-Trasssenbedarf

ELT

Detaillierung ELT-Konzept

Verbrauch ELT-Gebäude

HVAC/RRT

Detaillierung HVAC-Konzept

Bau/ Architektur

Sicherheitskonzept

Vorgaben ST Layout

Prozeß Rohrtrassenbedarf

Integrierter Aufstellungsplan

Angebot auswerten

Anfrage Ausrüstung

GMP-Pläne

Rohrklassenübersicht

vorläufiges Mengengerüst RL/Armaturen

Systembeschreibung

Vorläufiges Mengengerüst

Anfrage kritischer Komponenten

stat. Lasten

Pattern Spec Meßstellen

Systembeschreibung PLS

Vorläufiges Mengengerüst Instrumentierung

Systembeschreibung IT

Anfrage IT-System

Auslegung ELT

Aufstellungsplanung Trassenbedarf

Vorplanung Bau Brandabschnitte Fluchtwege

Entwurfsplanung Vorstatik

Review Sicherheitstechnik

Mechanical Design Data

Listen aus P&ID

Anfrage RL/Armaturen

Stahlbau Spezifikation

Anfrage Instrumentierung/PLS

Aufstellungspläne Schalträume

Handling Logistik

Anfrage Stahlbau

Rohrtrassen Prozess/Utilities

endgültig integrierter Aufstellungsplan

endgültiges Mengengerüst RL/ Armaturen

endgültiges Mengengerüst Instrumentierung / PLS

Layout Serverräume Aufstellungsplan Komponenten

Endgültige Auslegung ELT

Auswertung Angebote RL/ Armaturen/Stahlbau

Plant Design

Auswertung Angebote

HVAC/RRT

Auswertung Angebote

PLT

IT

Auswertung Angebote

ELT

ELT-Raum Layout

Korrektur Entwurfsplanung

Bau/ Architektur

Baumassen

Sic herheitstechnik

Bieterliste

Definition Einkaufsbedingungen

Montage

Faktorenabschätzung

Liste kritischer Parameter

Design Review

GO/GF Beschreibung

Baugenehmigungsunterlagen

Beschaffung

Risikoanalyse

Utilities

Ausrüstung

Behördenengineering

Compliance

Prozeßtechnik

Abgleich BFD, PFD, P&ID, Vefahrensbeschreibung

Überprüfung Auslegung

endgültiges Layout Technikzentrale

Endgültige Verbraucherliste ELT

stat. Lasten

Massenschätzung Stahlbau

Auftraggeber

Projektleitung

Gesamttermin / Kostenplan

Abgleich BFD, PFD, P&ID, Vefahrensbeschreibung

Angebot auswerten

stat. Lasten

Detailliertes Konzept Bau

Angebot auswerten

Angebot auswerten

Spezifikation Spezialausrüstung

Spezifikation Ausrüstung

Plant Design

P&ID 100%

Spezifikation Spezialausrüstung

Ausrüstung

Sic herheitstechnik

P&ID 50%

GMP-Review Layout

Anfrage Montage

Auswertung Angebote

Behördenengineering

Auswertung Angebote

Beschaffung

Anfrage Expending

Montage

GMP-Review Ausrüstungs Specs

Compliance

Version 1.0

Go Architektur Go HVAC

Project-Time

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Simulation Services •

Visualization of batch data and bottlenecks

•

Illustration of batch interaction

•

Analysis and optimization of capacity, utilization and interaction of different equipment and systems

•

Fill level analysis: •

Supply and storage vessels

•

Process equipment

•

Optimization of resources (personnel, plant, peripheries)

•

Concurrency analysis of each utility

•

Detailed utility evaluation

Gantt chart

Total Quantity

Weekly Consumption

•

Assured planning basis for supply and disposal systems by simulated production and coordination of utilities

•

Experimental studies for new building, rebuilding, and extension building

•

Summary of complex process dynamics

Time (h) time [h]

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Engineering of Equipment 

Use of aspentech as in-house tool



Calculation of main parameter of equipment as base for equipment specification



Specification and datasheets

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Advanced Plant Design using 2D / 3D CAD-Systems Piping PDS/PDMS

Process Equipment

Building Services VENTURIS/ ACAD

PDS/PDMS

Laserscanning

Architectural / Civil Steel Works PDS/PDMS/ ADT/ACAD/…

Input

Input

Input

MTO PDS-2D/ Smart Plant P&ID/ Comos PT

Input

Input

„Intelligent“ P+I-Diagrams/Lists

Check

Check

Collisionschecks Collision Check

PIPING Stress Calculations

Check

PDS/PDMS/ ACAD/MS

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Output

Output

Equipment Arrangement

Output

Check Output

Caesar II/ Rohr 2

Design Review

Isometrics

Simulation

Material Management

PDS/PDMS/DXF/ DGN

INOSIM – batch plant simulation – eM-plant

PDS/PDMS/SQL/ ASCII/XLS

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Stress Calculations • Simplified calculation acc. to AD 2000 Merkblatt HP100R Germany • Alternatively stress-calculations for pipes according to • ASME B 31.3 chemical plants • ASME B 31.1 power stations • ASME NC 3600 nuclear power plants

• EN 13480-3 Europe • FDBR Germany • KTA 3201.2, KTA 3211.2 nuclear power plants • Further applications • High pressures / high temperatures • Connections to rotating equipment • Two phase fluid flows or condensates • Special materials or double pipes

• Type of program: ROHR 2 or CAESAR II

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•

3D-Laserscanning is the ideal tool to grasp the asbuilt-state of an installation in an efficient manner, without manual survey on site

•

In post-treatment a 3D-CAD-model can be generated from these data, pipe-classes and equipment parameters may be added

•

In a minimum the scan data may be used as “background” for the design of new systems, ensuring a clash free design

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3D model after Post-Processing

Laser-Scan-Result

Situation on site

Revamp-Projects: Laser Scanning

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Skid Design and Construction

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Amount of control levels

Integrated Automation Solutions ERP i.e. SAP R/3®

Enterprise Business Systems

MES / MIS Manufacturing Execution / Information System PCS Process Control System or SCADA-System

SPS, Fieldbus, Remote I/O, MCC, MVI Actors, Sensors

Site Operation Systems

Plant Operation Systems

Field level (peripheral)

Inside control level 20

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Qualification and Validation Retro- and prospective Risk analysis

• Process equipment • Utilities • HVAC systems and cleanrooms

Engineering DQ, IQ, OQ

Planning Document preparation Execution

• Computerized systems: • PLC, PCS, MES, ERP

VMP

PQ

CV, PV

Production

• Manufacturing processes • Cleaning processes • Laboratory equipment • Analytical methods

VMP - Validation Master Plan

OQ - Operational Qualification

CV - Cleaning Validation

PCS - Process control system

DQ - Design Qualification system

PQ - Performance Qualification

PLC - Programmable logic controller

MES – Management execution

IQ - Installation Qualification

PV - Process Validation

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ERP – Enterprise resource

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Integrated Approach Qualification (Plants According to GMP-Regulation) Phase I

Basic Engineering

Detail Engineering

URS review

FAT/SAT/IQ/OQ

DQ execution

GMP review

Inquiries to suppliers

FAT

VMP 1. version

Proposal evaluation

Risk impact Impact analysis Analyses DQ prep.

VMP Approval

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Construction / Implementation

Phase II

Definitions

Auditing suppliers

Construction Phase

Start up Phase

Validation

IQ Execution SAT

OQ Execution SAT

PQ / PV

Calibration

Approval of SOPs RV

Draft SOPs Review of suppliers Doc.

Test Phase

Draft OQ protocols

Operator training

Draft of IQ protocols

Riskanalysis

Purchase Decision

Approval of DQ Protocols

Approval of IQ Protocols

Approval of OQ Protocols

Handover to Client

© M+W Group

Environment and Energy

Environment • CO2 Footprints (analyses, balances, optimizing, solutions) • Green building (preparation of the certificate) • Water- and wastewater management • Waste management

Energy • Power plants • Alternative energy production solutions (solar / biomass) • Energy optimization (balances, block-type thermal power station) • Heat recovery

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Four Good Reasons For M+W Group Opportunities

Experience with modular solutions

• Access to global vendor markets • Global procurement possibilities through M+W Group platforms and networks • Use of M+W Group / M+W Process Industries platform in various regions and markets of the world (China, India, East-Europe...)

• Modelling of process groups subject to prefabrication • Design, assembling and testing of all process groups by a specialized and qualified vendor. • Fast start-up and commissioning at customers

M+W Process Industries creates additional values …

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Competitiveness

Best technical solution …

• Many of our customers work in a low margin market with high competition  cost awareness is integrated in our planning • Low-cost solutions with strict ensuring of quality requirements

• Integrated project approach • Analysis of complete process flow • Competence through numerous projects • Multitude of clients from different industries • Neutral and client-orientated solutions © M+W Group

General Environmental, Health and Safety Strategy Our EHS vision

Our EHS mission

To maintain our position as „Best-In-Class“ EHS performer benchmarked against top tier competitors

We are committed to an injury free workplace where everybody goes home safe and adverse impact to the environment is unacceptable

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Principles driving our mission

How we will fulfill our mission

Robust systems and a leadership safety culture Each person leads and serves by example Promote the sharing of skills and information (transparency) All personnel must positively challenge unsafe conditions and behavior

By continuously standardizing, improving, and effectively implementing world-class EHS performance systems that eliminate, reduce and control risk to people and the environment

© M+W Group

Our Core Values Our success is derived from creating value for all our stakeholders - our customers, employees, suppliers and shareholders. We will continuously improve our service and foster the teamwork of our Group. People and Environment

Credibility

• We are committed to an injury free

• We keep our promises and meet our commitments. • The courage to remain truthful ensures fairness in all our relationships.

workplace where everybody goes home safe. • Respect for people means to care for them and to protect the environment in which we live and work. Customer Orientation • We commit ourselves to a long-term

Cultural Diversity • We cultivate our global spirit through

partnership focused on creating value for our customer. • Customer satisfaction is achieved through the high quality of our people and their work.

mutual respect and the sharing of experiences. • Cultural diversity is a strength that creates a richness within our Group.

Trust • We build relationships with

Pride in our Employees • We create a future together by nurturing

customers’ employees and suppliers on a foundation of trust and respect. • Leadership must ensure a good balance between the level of empowerment and controls.

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an entrepreneurial spirit through rewarding courage and creativity.

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