INTERNATIONAL

SYMPOSIUM MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK GERMANY MAY 5TH – MAY 7TH, 2017

Content

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

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CONTENT Welcome............................................................................................................. 5 Scientific programme.......................................................................................... 6 Registration....................................................................................................... 11 Directions.......................................................................................................... 12 Transportation services...................................................................................... 13 Option 1: Basic bus shuttle service............................................................... 13 Option 2: Extended bus shuttle service........................................................ 13 Option 3: Extended bus shuttle service........................................................ 13 Hotel.................................................................................................................. 14 Social programme.............................................................................................. 15 Get-together – dinner at Hotel Schwanen, Köngen....................................... 15 Meet the chairmen and speakers at Burg Teck.............................................. 15 About Mayo Clinic............................................................................................. 16 Faculty............................................................................................................... 17 Sponsors ........................................................................................................... 34 Further information............................................................................................ 36 Registration form............................................................................................... 39

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VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 5TH – MAY 7TH, 2017

Preface of the District Council Text is coming ...

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VERTRAUEN HEISST JETZT MEDIUS.

NEUER NAME - VERTRAUTE STÄRKEN: DIE KREISKLINIKEN ESSLINGEN HEISSEN JETZT MEDIUS KLINIKEN

WELCOME The Vaskulitiszentrum Süd Tübingen-Kirchheim, Germany and Mayo Clinic, USA are pleased to announce a unique 2 1/2-day conference for clinicians, researchers and trainees with a common interest in the aetiology, diagnosis and management of multi-system disorders. The conference will be held on May 5th to 7th, 2017 in the conference center “Schlossberghalle” in Dettingen, a suburb of Kirchheim-Teck close to Stuttgart. We invite students, trainees, researchers, consultant physicians / surgeons /pathologists and other health professionals with an interest in multi-system diseases including vasculitis, interstitial lung diseases, collagen vascular diseases, and inflammatory ophthalmic and renal disease to attend. Emphasis will be on cross-discipline collaboration in advancing the field.

Welcome

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 5TH – MAY 7TH, 2017

COURSE DIRECTORS: Ulrich Specks Connor Group Foundation Professor of Medicine, Chair, Division of Pulmonary & Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA

Jörg Henes PD Dr. med., Section Chair Rheumatology, Medizinische Klinik II, Universitätsklinikum Tübingen, Tübingen, Germany

Bernhard Hellmich Prof. Dr. med., Chair, Klinik für Innere Medizin, Rheumatologie und Immunologie, Vaskulitiszentrum Süd, medius KLINIK KIRCHHEIM, Akademisches Lehrkrankenhaus Universität Tübingen, Kirchheim/Teck, Germany

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Scientific programme

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

SCIENTIFIC PROGRAMME Friday May 5th, AFTERNOON 15:00 Get together Schlossberghalle 15:30 Welcome and Introduction U. Specks, B. Hellmich NEWS IN NEPHROLOGY Current approaches to diagnosis of renal diseases Chairs: V. Torres, D. Alscher 15:45 Glomerulonephritis - pathology for the practicing clinician – S. Sethi 16:15 Polycystic kidney disease: from bench to bedside – V. Torres 16:45 Coffee break Glomerulonephritis: What is new? Chairs: F. C. Fervenza, N. Heyne 17:15 17:45 18:15 18:45

Membranous nephropathy - a recent paradigm shift – F. C. Fervenza Membranoproliferative glomerulonephritis - practical implications of recent discoveries – S. Sethi Biologic variables affecting renal outcomes in lupus nephritis – F.C. Fervenza Managing alveolar hemorrhage in pulmonary-renal syndromes – U. Specks

Optional: 19:20 Bus transfer to Hotel Schwanen, Köngen 19:45 Reception Hotel Schwanen, Köngen 20:15 Dinner Hotel Schwanen, Köngen

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Saturday May 6th, MORNING RHEUMATOLOGY & MORE Recent advances in rheumatology Chairs: S.R. Ytterberg, C. Fiehn 09:00 09:30 10:00 10:30

Diagnosis and management of polymyositis / dermatomyositis / anti- synthetase syndrome – S.R. Ytterberg Hot topics in the management of rheumatoid arthritis – E.L. Matteson What’s new in the management of scleroderma – S.R.Ytterberg Coffee break

Scientific programme

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 5TH – MAY 7TH, 2017

Novel approaches to treatment and diagnosis Chairs: N. Leung, R. Meyer 11:00 11:30 12:00 12:30 13:00

Guideline approach to diagnosis of PAH including screening in pati ents with Scleroderma – C.D. Burger Management of refractory autoimmune diseases: the role of antimyeloma therapies – N. Leung Autologous stem cell transplantation in scleroderma: what have we learnt so far? – J. Henes Ophthalmology of autoimmune disease – J. A. Garrity Lunch break

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Scientific programme

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

Saturday May 6th, AFTERNOON RESPIRATORY ROUND-UP Interstitial lung diseases Chairs: A. H. Limper, J. Hetzel 14:00 14:30 15:00 15:30

Interstitial lung disease (ILD): terminology, pattern recognition and their practical implications – A.H. Limper Connective tissue disorder associated ILD: RA, scleroderma, PM/DM – E.L. Matteson Management of IPF: trial results and daily practice – A.H. Limper Coffee break

Management of difficult to treat pulmonary – diseases and complications Chairs: U. Specks, M. Kohlhäufl 16:00 16:30 17:00 17:30

Update in PAH treatment: More is better – C.D. Burger Pneumocystis pneumonia - what everybody needs to know about it – A.H. Limper Asthma, Eosinophilia, and systemic disease: clues for differential diag nosis and treatment – B. Hellmich CPC format case discussions with faculty (local residents present local cases –“stump the chumps”)

Optional: 18:30 Bus transfer and walk to Burg Teck 19:30 Dinner at Burg Teck

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Sunday May 7th, MORNING VASCULITIS REVISITED Vasculitis I Chairs: E. Matteson, B. Hellmich 09:00 09:30 10:00 10:30

Update on diagnosis and management of large vessel vasculitis – E.L. Matteson ANCA diagnostics: state of the art – E. Csernok Treatment of ANCA-associated vasculitis in 2017 – U. Specks Coffee break

Scientific programme

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 5TH – MAY 7TH, 2017

Vasculitis II Chairs: U. Specks, J. Henes 11:00 11:30 12:00 13:00 13:15

Lessons from the RAVE trial – beyond the headlines – U. Specks What‘s new in treating patients with Behcet’s disease – T. Xenitidis CPC format case discussions with faculty (local residents present local cases –“stump the chumps”) Wrap-up Farewell lunch

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Universitätsklinikum

Kompetenz

Tübingen

mit Herz

www.uniklinikum-tuebingen.de

Ihre Karrierewege an Klinikum & Medizinischer Fakultät www.medizin.uni-tuebingen.de/Mitarbeiter/Karriere

REGISTRATION SYMPOSIUM MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE 2017 - „MAYO CLINIC DAYS 2017“ Number: Date: Location:

Registration

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 5TH – MAY 7TH, 2017

A171-41012 Friday, May 5th, 2017, 3pm to Sunday, May 7th, 2017, 2pm Schlossberghalle, Dettingen/Teck, Germany

Costs: Advance Registration EUR 149 (until March 1st, 2017) Late Registration EUR 190 (from March 1st, 2017) What is included in the conference fee? „„ Admission to all scientific sessions „„ Admission to the industry exhibition „„ Your own abstract booklet with key slides from all presentations „„ Catering with lunch, snacks and drinks Additional services (for details see the following pages) „„ Transportation services „„ Hotel reservation „„ Social programme Please register using the form at the end of this booklet or our congress-homepage (http://akademie.kk-es.de/autoimmune-conference-2017/).

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Directions

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

DIRECTIONS

Location Address Schlossberghalle: Teckstraße 35, 73265 Dettingen unter Teck Hotel Schwanen: Schwanenstraße 1, 73257 Köngen Burg Teck: Teckstraße 100, 73277 Owen Best Western Hotel: Europastraße 13, 72622 Nürtingen

Distance 0 km 15 km 6 km 18 km

How to get there by car: Coming from the A8 motorway, take exit 57 (Kirchheim Teck-Ost). Direction Dettingen unter Teck on the B465. Follow the signs to the Schossberghalle. There are ample parking spaces at the Schlossberghalle. Access by train and bus: (You can find your connection under www.efa-bw.de) The train station Kirchheim has connection to Stuttgart with the S1 line. At the central bus station there is a connection to the Schlossberghalle with the bus line 175 or regional bus line RBS 176. The stop is directly in front of the Schlossberghalle. By plane: There are three options for you. Use a taxi (distance: approx. 25 km), use the express bus connection line X10 (destination Kirchheim, duration 40 minutes) or use the S-Bahn train to Stuttgart (continue by train and bus, duration 1:40 hours).

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TRANSPORTATION SERVICES Transportation services are not included. But don´t worry - you can book our additional shuttle services between hotel, conference location and our social events easily. Please tick the appropriate box on the registration form, if you want to book one of the following services:

OPTION 1: BASIC BUS SHUTTLE SERVICE EUR 40 We offer you a bus shuttle service on all 3 conference days between the Best Western Hotel, Nürtingen and our conference location in Dettingen. Our bus will pick you up in the morning and bring you back at the end of the day.

Transportation services

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 5TH – MAY 7TH, 2017

OPTION 2: EXTENDED BUS SHUTTLE SERVICE EUR 10 If you want to join our social event on Friday evening at Hotel Schwanen in Köngen we will organize your transport from the conference location Dettingen to Köngen and then back to the Best Western Hotel in Nürtingen.

OPTION 3: EXTENDED BUS SHUTTLE SERVICE EUR 10 Also for the social event on Saturday evening on Burg Teck we offer you a shuttle service. We will bring you from our conference location in Dettingen to the parking lot where we start our walk up to Burg Teck. After the event we bring you back to Dettingen. If you need transportation back to the hotel we will gladly bring you there. There is also the possibility for people with physical limitations to book a „doorto-door“-shuttle. With this add on you won´t have to walk up to Burg Teck. This service is free but can only be used by a limited amount of people (included in the price for Option 3, just tick the box on the registration form for the „addon-service“).

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Hotel

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

HOTEL For accommodation we recommend the Best Western Hotel in Nürtingen. We reserved a special contingent of double and single rooms for all participants of the event. If you want to book one of these rooms please contact the hotel directly and use keyword and contingent number for booking (see below).

BEST WESTERN Hotel Am Schlossberg in Nürtingen Keyword: „Autoimmunity Kirchheim 2017“ Contingent number: 1164 [email protected] Fax: +49 7022 704-346 You`ll find the registration form for the hotel booking at the end of this booklet.

ADDRESS: BEST WESTERN Hotel Am Schlossberg in Nürtingen Europastraße 13 72622 Nürtingen

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SOCIAL PROGRAMME GET-TOGETHER – DINNER AT HOTEL SCHWANEN, KÖNGEN If you don´t want to sit alone in your room on Friday evening (May 5th), you´ll have the chance to join our get-together dinner at Hotel Schwanen. Have a nice meal and some good conversation with your colleagues.

Social programme

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 5TH – MAY 7TH, 2017

Price: EUR 50 (incl. four-course meal, excl. drinks) OPTIONAL Bus shuttle (Option 2): EUR 10 (Dettingen - Köngen - Best Western Nürtingen)

MEET THE CHAIRMEN AND SPEAKERS AT BURG TECK All day long we saw the impressive Burg Teck from our congress location. On Saturday evening we do some exercise to take a closer look at this medieval castle. After a short bus transfer we make our way up. While walking up an romantic path to Burg Teck (approx. 40 min) you´ll enjoy the marvelous landscape of the Swabian Alb and its surroundings. On the top (about 775 m above sea level) we´ll find the legendary Burg Teck. Archaeological finds prove its existence since the 11th century. In this historical atmosphere we enjoy a traditional swabian meal and music from the middle-age. Here you have the possibility to meet the speakers of the event and get connected with your colleagues.Then after a tasty and enjoyable evening we do our walk back - be prepared for some adventure. Price: EUR 60 (incl. meal, excl. drinks) OPTIONAL Extended bus shuttle service: EUR 10 (Dettingen - Teck - Dettingen - Best Western Nürtingen) Please note: Highly recommended are good shoes (e.g. sneakers). For people who aren´t able to walk this distance we arranged a special shuttle service. Please consider this option during the booking procedure (add on to Option 3).

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About Mayo Clinic

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

ABOUT MAYO CLINIC Mayo Clinic is a nonprofit medical practice and medical research group based in Rochester, Minnesota. It employs more than 4,500 physicians and scientists and 57,100 allied health staff. The practice specializes in treating difficult cases through tertiary care. Each year, more than 1.3 million patients from all 50 states and from more than 150 countries are seen at one of the Mayo Clinic facilities. Mayo Clinic offers highly specialized medical care, and a large portion of the patient population are referrals from smaller clinics and hospitals from across the upper Midwest and the United States as a whole. Mayo Clinic researchers contribute to the understanding of disease processes, best clinical practices, and translation of findings from the laboratory to the clinical practice. Nearly 600 doctoral level physicians and research scientists are employed, with an additional 3,400 other health personnel and students with appointments in research. In 2015, more than 2,700 research protocols were reviewed by the Mayo Clinic Institutional review board and 11,000 ongoing human research studies. These research initiatives led to more than 7,300 research publications and review articles in peer-review journals. It spends over $660 million a year on research. William Worrall Mayo settled his family in Rochester in 1864 and opened a medical practice that evolved under his sons into Mayo Clinic. Mayo Clinic is widely regarded as one of the United States‘ greatest hospitals and ranked No. 1 in the country] on the 2016–2017 U.S. News & World Report List of „Best Hospitals“ of the United States, maintaining a position near the top for more than 25 years. It has been on the list of „100 Best Companies to Work For“ published by Fortune magazine for thirteen consecutive years. It continued to achieve this ranking through 2015. In addition to their flagship hospital in Rochester, the Mayo Clinic has major campuses in Arizona and Florida. The Mayo Clinic Health System also operates affiliated facilities throughout Minnesota, Wisconsin, and Iowa.

Source: https://en.wikipedia.org/wiki/Mayo_Clinic

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FACULTY DOMINIK ALSCHER

Faculty

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

Professor of Medicine, Chair, Klinik für Nephrologie, Robert-Bosch-Krankenhaus, Stuttgart, Germany Dr. Mark Dominik Alscher is the executive chief physician of the Robert-Bosch-Hospitals, a group of hospitals in South Germany. Additionally he is chief of the department of Nephrology, General Internal Medicine and Emergencies. He has published over 180 scientific papers in the areas of peritoneal dialysis, acute kidney failure and medical knowledge systems. He is author of several chapter in textbooks of nephrology in Germany. Additionally he is the president of the German Society of Nephrology, president of the Southwest-Germany Society of Internal Medicine and member of working groups regarding quality assurance in dialysis, telemedicine, certification of hospitals and local member groups.

CHARLES D. BURGER Professor of Medicine, Division of Allergy and Pulmonary Medicine, Mayo Clinic College of Medicine, Jacksonville, FL, USA Dr. Burger is a graduate of the Wake Forest School of Medicine, completed his Internal Medicine Residency at Vanderbilt University and Pulmonary & Critical Care Medicine fellowship at the Mayo Clinic, Rochester Minnesota. He’s been on the faculty at the Mayo Clinic in Jacksonville Florida since 1991 and is currently Professor of Medicine at the Mayo Clinic School of Medicine and Science. He is Medical Director of the accredited Pulmonary Vascular Center and is past Chair of the Division of Pulmonary & Critical Care Medicine at the Mayo Clinic in Jacksonville Florida. His primary clinical and research interest has been pulmonary arterial hypertension (PAH), principally diagno-

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Faculty

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

sis, treatment and prognosis. Substantial contributions to the literature include the role of screening for associated conditions, pharmaceutical treatment trials, and understanding the appreciable burden of hospitalization in patients with PAH. More recently investigation of overall healthcare burden of PAH has been an area of additional inquiry.

ELENA CSERNOK Reference Laboratory for Vasculitis Autoimmune Serology, Klinik für Innere Medizin, Rheumatologie und Immunologie, medius KLINIK KIRCHHEIM, Akademisches Lehrkrankenhaus der Universität Tübingen, Germany Dr. Elena Csernok, former head of the Vasculitis Diagnostic and Research Unit at the Department of Rheumatology and Immunology, Klinikum Bad Bramstedt, University of Lübeck, is specialized in immunology and rheumatology with main activities in clinical immunology and translational medicine within the field of autoimmune diseases. She graduated from the University of Iasi and received her PhD from the University of Lübeck, Germany. Her work focuses on clinical immunology and vasculitis and began in the mid-eighties when she proceeded many projects investigating immunopathology of ANCA-associated vasculitides, especially granulomatosis with polyangiitis („Wegener`s granulomatosis“). After retirement from full-time work she is active in immunodiagnostic studies focused on rheumatic disorders, especially in the vasculitis field, and participates in development of effective and innovative methods for ANCA diagnostic.

FERNANDO C. FERVENZA

M.D., Ph.D. Professor of Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN, USA Fernando C. Fervenza, MD. D.Phil (Oxon – Jesus College). Is a Professor of Medicine at the Mayo Graduate

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School of Medicine, Rochester, MN, USA. He graduated in Medicine at the Pontificia Universidade Catolica do Rio Grande do Sul, Brasil. He underwent his clinical nephrology training at the Oxford Renal Unit from 1985 to 1991. Subsequent training included Post-doctoral Fellowship at Stanford University, USA (1993-1997). He is a Fellow of the American Society of Nephrology, Fellow of the American College of Physicians, past Member of the American Board of Internal Medicine, Nephrology section, Associate Editor of the Journal of the American of Nephrology and Up-To-Date Section Editor for Glomerular Disease. His area of interest is in pursuing patient-oriented research projects aiming to bring new bench research discoveries to the bedside treatment of patient with glomerular diseases.

Faculty

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

CHRISTOPH FIEHN Professor of Medicine, Chair, Klinik für Rheumatologie, ACURA Kliniken, Baden-Baden, Germany Christoph Fiehn, Prof. Dr. med, is Medical Director of the Department for Rheumatic Diseases Baden-Baden since 2004. He graduated at the University of Heidelberg in 1991. After serveral years of national and international experience in rheumatology he got his habilitation from the University of Heidelberg in 2004. Prof. Fiehn is scientifically well represented in his field, with many peer-reviewed publications respectively, and renowned in Germany as well as internationally. His scientific and clinical interests include gerontorheumatolgoy, the modern therapy of rheumatoid arthritis, clinical pharmacology of methotrexate and systemic lupus erythematosus. Christoph Fiehn is a member of several societies and expert working groups. In 2013, as a member of the working group “Rheumatological Specialist Assistance” Prof. Dr. Christoph Fiehn, received the Kußmaul Medal of the German Society of Rheumatology for special merits in Rheumatology.

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MabThera ist mehr. Die zielgerichtete B-Zell-Therapie bei ANCA-assoziierter Vaskulitis1.

von

nach

„ Signifikant besseres Ansprechen bei Patienten mit Rezidiv2 bzw. PR3-AAV Positivität3 „ Vorteil durch CYC-Einsparung unter MabThera®4: erhöhtes Tumorrisiko vermeiden, Fertilitätserhalt

1 Zugelassen in Kombination mit Glucocorticoiden zur Remissionsinduktion bei erwachsenen Patienten mit schwerer, aktiver Granulomatose mit Polyangiitis und Mikroskopischer Polyangiitis. 2 Stone JH, Merkel PA, Spiera R, et al. Rituximab versus cyclophosphamide for ANCA-associated vasculitis. N Engl J Med 2010;363:221–32. 3 S. Unizony et al. Ann Rheum Dis 2015;0:1–4; 4 F. Moosig et al. Dtsch Med Wochenschr 2014;139:2248-2253

Bezeichnung des Arzneimittels: MabThera® 100 mg/500 mg Konzentrat zur Herstellung einer Infusionslösung. Wirkstoff: Rituximab, ein gentechn. hergest. monoklon. chimärer Antikörper der Klasse IgG. Zusammensetzung: Eine Durchstechfl. MabThera enthält: 100 mg/10 ml bzw. 500 mg/50 ml Rituximab. Sonst. Bestandteile: Natriumcitrat, Polysorbat 80, Natriumchlorid, Salzsäure, Natriumhydroxid, Wasser für Injekt.zwecke. Anwendungsgebiete: MabThera in Komb. mit Methotrexat ist für die Behandl. erw. Pat. mit schwerer aktiver rheumatoider Arthritis angezeigt, die ungenügend auf andere krankheitsmodifizierende Antirheumatika (DMARDs) einschl. einer oder mehrerer Ther. mit Tumornekrosefaktor(TNF)-Hemmern angesprochen oder diese nicht vertragen haben. MabThera® in Komb. mit Methotrexat vermindert das Fortschreiten der radiologisch nachweisbaren Gelenkschädigung u. verbessert die körperliche Funktionsfähigkeit. MabThera in Komb. mit Glukokortikoiden wird angewendet zur Induktion einer Remission bei erw. Pat. mit schwerer, aktiver Granulomatose mit Polyangiitis (Wegenersche Granulomatose) (GPA) u. mikroskopischer Polyangiitis (MPA). Gegenanzeigen: Überempfindl. gg. den Wirkstoff, gg. Mausproteine od. einen der sonst. Bestandt. des AM. Aktive, schwere Infekt., stark geschwächtes Immunsystem, schwere Herzinsuff. (NYHA Klasse IV) od. schwere, unkontrollierte Herzerkrank. Nebenwirkungen: Infusionsbed. NW einschl. Schmerz. an der Infus.-stelle, allergische Reakt. (bei Indikation Autoimmunerkrank. auch bis zu 24 h nach der Infus.), die auch mit einer Verschlecht. bestehender Herzerkrank.verbunden sein können. Bakterielle od. virale Infekt. wie Sepsis, Pneumonie, Atemwegsinfekt., Herpes zoster, Hepatitis B, Harnwegsinfekt., Pilzinfekt. (verurs. z. B. durch Pneumocystis jirovecii), Hepatitis-B-Reaktivierung (einige mit tödlichem Ausgang). Sehr selten: PML, die tödlich verlief. Schwere Hautreakt. wie SJS od. TEN (einige mit tödlichem Ausgang). Indikation Autoimmunerkrank: Blutdruckveränd., erhöhter Blutdruck, Übelkeit, Hautreakt., Ausschlag, Erröten (mit Hitzegefühl), Hautausschlag einschl. Akne od. Flecken auf der Haut, Juckreiz, Urtikaria, Fieber, Rhinitis, Zittern, Tremor, beschl. Herzschlag, Änd. des Herzrhythmus, Müdigkeit, Kopfschmerzen, Sinusitis, Schmerzen im Bauch, Rücken, in Muskeln, Händen, Füßen u./od. Gelenken, Erbrechen, Verdauungsstör., Sodbrennen, Durchfall, Verstopfung, Reizg. u./od. Geschwüre im Mund od. Rachen, Atemprobleme, Tinea pedis, Hypercholesterinämie, Parästhesie, Ischialgie, Migräne, Benommenheit, Schwindel, Alopezie, Depression, Angstgefühl, Ödeme, Entz./Reizg. u./od. Engegefühl der Lunge u. Rachen, Husten, Kurzatmigkeit, Komplex von Krankheitserschein. einige Wo. nach Infus., die einer Allergie ähneln, Neutropenie, vermind. Immunglobulinspiegel, verstopfte Nase, Nasenbluten, Muskelverspannung, Muskelzuckungen od. -zittern, niedrige Anzahl weißer Blutzellen u./od. Blutplättchen, Insomnia, Schwellungen an Händen od. Knöcheln, Anstieg der Kaliummenge im Blut, Anämie. Indikation NHL/CLL: Sehr häufig: bakterielle od. virale Infekt., Entzündung der Bronchien (Bronchitis), geringe Anzahl an weißen Blutkörperchen (mit od. ohne Fieber) od. Blutplättchen, Übelkeit, Alopezie, Schüttelfrost, Kopfschmerzen, verminderte Immunabwehr. Häufig: Sepsis, Lungenentzündung, Herpes, Erkältungen, Infekt. der Bronchien, Pilzinfekt., Infekt. unbekannten Ursprungs, Sinusitis, Hepatitis B, Anämie, Panzytopenie, Überempfindl., hohe Blutzuckerwerte, Gewichtsverlust, Schwellungen im Gesicht u. am Körper, erhöhte LDH Werte, erniedrigte Serumkalziumwerte, Parästhesie, Unruhe, Einschlafschwierigkeiten, Vasodilatation, Schwindel, Angstgefühl, erhöhte Tränenbildung, Stör. der Tränensekretion u. -bildung, Konjunktivitis, Ohrgeräusche u. -schmerzen, Herzinfarkt, unregelm. od. erhöhte Herzfrequenz, Hypertonie, Hypotonie einschl. orthostatische, Bronchospasmus, Entzündung/Reizung der Lungen/Nasennebenhöhlen od. im Rachen, Atemnot, laufende Nase, Erbrechen, Durchfall, Abdominalschmerzen, Reizung u./od. Geschwürbildung in Rachen u. Mund, Schluckbeschwerden, Verstopfung, Verdauungsstör., Essstör., Nesselsucht, verstärktes Schwitzen, Nachtschweiß, Myalgie, Gelenk-, Muskel-, Rücken- u. Nackenschmerzen, allgemeines Unwohlsein od. Unbehagen od. Müdigkeit, Zittern, Anzeichen einer Grippe, Multiorganversagen. Gelegentlich: Gerinnungsstör., aplastische hämolytische Anämie, geschwollene/vergrößerte Lymphknoten, düstere Gemütslage, Depression, Nervosität, Stör. der Geschmacksempfindung, Angina pectoris, Asthma, Sauerstoffmangel, Vergrößerung des Bauchraums. Sehr selten: erhöhte IgM-Antikörperspiegel, Stör. der Blutchemie, verursacht durch den Abbau absterbender Krebszellen, periphere Neuropathie, Gesichtslähmung, Herzinsuff., Gefäßentzündungen auch mit Hautveränderungen, Atemversagen, Darmwandperforation, schwere, potenziell lebensbedrohliche Hauterkrank. mit Blasenbildung, Nierenversagen, schwerer Sehverlust. Nicht bekannt: verzögerte Verminderung der weißen Blutzellen, infusionsbedingte sofortige Abnahme der Blutplättchen (auch mit tödlichem Verlauf), Gehörverlust, Verlust anderer Sinne. Veränderungen von Laborwerten. Dosierung: Rheumatoide Arthritis: zwei i.v. Infus. zu je 1000 mg im Abstand von zwei Wo. Weitere Behandl.-zyklen sind möglich. Die Notwendigkeit weiterer Behandl.-zyklen sollte 24 Wo. nach dem vorherigen Zyklus beurteilt werden. Granulomatose mit Polyangiitis u. mikroskopische Polyangiitis: zur Induktion einer Remissionsther. beträgt die Dosierung 375 mg/m2 KOF 1x wöchentl. als i.v. Infus. über einen Zeitraum von vier Wo. (insgesamt 4 Infus.) in Komb. mit Glukokortikoiden. Prämedikation: Prämed. mit Analgetikum, Antihistaminikum, Glukokortikoiden gem. Fachinformation beachten. Verschreibungspflichtig. Hinweise der Fachinformation beachten. Pharmazeutischer Unternehmer: Roche Registration Limited, UK-Welwyn Garden City. Weitere Informationen auf Anfrage erhältlich. Vertreter in Deutschland: Roche Pharma AG, 79630 Grenzach-Wyhlen. Stand der Information: Mai 2016.

JAMES A. GARRITY M.D. Professor of Ophthalmology, Department of Ophtalmology, Mayo Clinic College of Medicine, Rochester, MN, USA

Faculty

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

James A. Garrity received both a B.S. (Biochemistry) in 1976 and his M.D. in 1980 from the University of Minnesota (Minneapolis, Minnesota). After internship at Hennepin County Medical Center in Minneapolis, Garrity pursued residency training in ophthalmology at the Mayo Clinic and subspecialty training in neuro-ophthalmology and orbital surgery at University of Pittsburgh – Allegheny General Hospital (Pittsburgh, Pennsylvania). Garrity joined the Department of Ophthalmology at Mayo Clinic Rochester in 1986. He is the Whitney and Betty MacMillan Professor of Ophthalmology in the Mayo Medical School. In 1988 and 1995 Garrity received the Mayo Foundation Teacher of the Year Award for the Department of Ophthalmology, the Honor Award (1994) and Senior Honor Award (2006) from the American Academy of Ophthalmology. He was recognized as the Distinguished Mayo Clinic Clinician in 1999. He is the author or coauthor of more than 100 publications and is a scientific reviewer for several peer-review journals. His clinical practice and research interests involve Graves’ ophthalmopathy and orbital diseases.

BERNHARD HELLMICH Professor of Medicine, Chair, Klinik für Innere Medizin, Rheumatologie und Immunologie, medius KLINIK KIRCHHEIM, Akademisches Lehrkrankenhaus der Universität Tübingen, Germany Bernhard Hellmich, Dr. med., is Professor of Medicine at the University of Tübingen and Chair of the Department of Internal Medicine, Rheumatology and Immunology at the medius KLINIK KIRCHHEIM, Teaching Hospital of the University of Tübingen. He is Co-Director of the Vasculitis Center Tübingen-Kirchheim.

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Faculty

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

Prof. Hellmich received his MD degree at the University of Bochum, Germany. He completed his internal medicine residency at the Department of Medicine at the University Hospital Bergmannsheil in Bochum and his rheumatology training at the Rheumaklinik Bad Bramstedt and University of Lübeck. From 2002 - 2007 he was vice-chair of the department of rheumatology at the Rheumaklinik Bad Bramstedt and University of Lübeck. Prof. Hellmich’s clinical and research interests are in the field of vasculitis. He is clinical chair of the reference laboratory for ANCA-diagnostics at medius KLINIK KIRCHHEIM and is actively involved in multicenter clinical trials and cohort studies in different forms of vasculitis. Prof. Hellmich is lead author of the EULAR recommendations for conducting clinical trials and vasculitis and coauthor of the EULAR/ERA recommendations for management of small- and large vessel vasculitis and the 2017 German S-1 Guidelines for management of AAV.

JÖRG HENES Rheumatology Unit, Medizinische Klinik II, Universitätsklinikum Tübingen, Germany Joerg C. Henes M.D., P.h.D, is head of the division of rheumatology in the Department of Internal Medicine II at the University Hospital Tuebingen. He also is director of the Centre for Interdisciplinary Clinical Immunology, Rheumatology and Auto-inflammatory Diseases – INDIRA - at the University Hospital Tuebingen Dr. Henes received the M.D. and P.h.D degree from the Eberhard Karls University Tuebingen. His clinical and research interests are in the field of systemic sclerosis and vasculitis, especially in the treatment option with autologous stem cell transplantation and in fertility and pregnancy in patients with rheumatic diseases.

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JÜRGEN HETZEL Sektion Pneumologie, Medizinische Klinik II, Universitätsklinikum Tübingen, Germany Juergen Hetzel, M.D. is Associate Professor at the University Clinic of Tübingen. Dr. Hetzel received the M.D. degree from University of Ulm. He completed an internship and residency in internal medicine at University of Ulm. Additionally he qualified in Respiratory Medicine, Cardiology, Intensive Care Medicine and Sleep Medicine. Dr. Hetzel’s clinical and research interests are in the fields of interventional bronchoscopy, interstitial lung disease and lung cancer.

Faculty

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

NILS HEYNE Section Chair Nephrology, Medizinische Klinik IV, Universitätsklinikum Tübingen, Germany Nils Heyne, M.D., is Head of the Section of Nephrology and Hypertension at Tübingen University Hospital and Assistant Professor of Internal Medicine at the Eberhard-Karls-Universität Tübingen, Tübingen, Germany. He received his MD from the University of Tübingen in 1995. After training in experimental and clinical pharmacology, he worked as a resident in internal medicine before completing a fellowship in renal medicine. He was appointed Head of the Section of Nephrology and Hypertension in 2012 and serves as senior nephrologist at the Tübingen Collaborative Transplant Center. Nils Heyne is a member of several international societes and expert working groups. His scientific and clinical interests include nephroimmunology, transplantation and renal involvement in systemic disease with focus on aHUS, multiple myeloma and diabetes.

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Faculty

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

MARTIN KOHLHÄUFL Professor of Medicine, Chair, Klinik für Pneumologie, Klinik Schillerhöhe, Robert-Bosch-Krankenhaus, Gerlingen, Germany Prof. Dr. Martin Kohlhäufl Studied medicine at the University of Erlangen-Nuernberg and the University of Pennsylvania, Philadelphia, PA, USA. Prof. Dr. Martin J. Kohlhäufl received his MD degree from the University of Erlangen-Nuernberg in 1988. From 1987 to 1995 he was scientific Assistant at the University Hospital of the Johannes-Gutenberg-University. From 1987 to 1995 he was Intern at the Hospital Darmstadt, Teaching Hospital of the University of Frankfurt and from 1995 to 2002 he was Intern at the Clinic Munich-Gauting, Center for Pneumology and Thoracic Surgery as well as scientific assistant and medical officer (Head) of the Clinical Research Group ‚Aerosol Medicine‘ of the Institute for Inhalational Biology of the GSF-Research Center for Environment and Health Munich-Neuherberg with sponsorship by the Federal Ministry of Education, Sciences, Research, and Technology. Since 2006 he was executive senior Physician at the Asklepios Clinic, Munich-Gauting, Center for Pneumology and Thoracic Surgery. Since 2007 he is Chief Physician at the Hospital Schillerhoehe Center for Pneumology and Thoracic Surgery at the Robert-Bosch-Hospital, Stuttgart Academic Teaching Hospital of the University of Tuebingen. He is member of many scientific communities (i.e. European Society of Medical Oncology (ESMO), European Respiratory Society, International Society of Aerosols in Medicine) and reviewer for scientific journals (i.e. European Journal of Pharmaceutical Sciences, American Journal of Respiratory and Critical Care Medicine, Thorax).

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NELSON LEUNG M.D. Professor of Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN, USA

Faculty

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

Dr. Leung graduated from Creighton University School of Medicine. He completed his internship at the University of Iowa Hospitals and Clinic. From there, he went to the Mayo Clinic Rochester where he completed his residency in Internal Medicine. It is there that he completed his Nephrology fellowship training. He currently has a joint appointment in the Division of Nephrology and Hypertension, and the Division of Hematology. He has an academic rank of professor of Medicine. His main interest is in monoclonal gammopathy related kidney diseases. He has written extensively on renal amyloidosis, myeloma cast nephropathy and monoclonal immunoglobulin deposition disease. He introduced the concept of monoclonal gammopathy of renal significance and has made substantial contributions in the treatment of paraprotein related kidney diseases. He is the current president of the International Kidney and Monoclonal Gammopathy Research Group.

ANDREW H. LIMPER Professor of Medicine, Division of Pulmonary & Critical Care Medicine, MayoClinicCollege of Medicine, Rochester, MN, USA Dr. Andrew Limper attended the University of Illinois at Urbana-Champaign, graduating Cum Laude with highest distinction in organic chemistry and physiology in 1980. Dr. Limper subsequently attended the University of Illinois College of Medicine at Peoria, graduating first in his class with honorary induction into Alpha Omega Alpha academic fraternity. During his senior year of Medical School, Dr. Limper received the Spencer Williamson Award for Excellence in Internal Medicine. He subsequently completed both Internal Medicine and

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Janssen-Cilag GmbH

DE/HUG/4616/1059

Der Pen.

Pulmonary-Critical Care training at the Mayo Graduate School of Medicine in Rochester, Minnesota, receiving recognition as an Outstanding Achievement Awardee of the Graduate School of Medicine. Following a research fellowship at Washington University, Dr. Limper returned to join the staff of Mayo Clinic Rochester where he has achieved the rank of Professor of Medicine. He currently serves as Associate Chair of the Department of Medicine for Research and Director of the Pulmonary Diseases Research Unit, Professor of Medicine. Dr. Limper is a clinical expert in interstitial lung diseases, and drug-induced lung diseases, and pulmonary fungal infections. He has authored in excess of 210 manuscripts, and has mentored dozens of trainees and junior faculty. Dr. Limper’s research program focuses on identifying new agents for treatments of lung fibrosis, as well as improving treatments of lung infections in immunocompromised patients. He has served as a frequent consultant to the National Institutes of Health. He is an elected member of the American Society of Clinical Investigation, and is Past President of the American Association of Pulmonary and Critical Care Program Directors. He has received the Distinguished Alumnus Award from his University of Illinois College of Medicine in Peoria. Dr. Limper holds two patents related to his work in pulmonary infection, and continues to seek new means to diagnose and treat patients with lung fibrosis and lung infection.

Faculty

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

ERIC L. MATTESON M.D. Professor of Medicine, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN, USA Eric L. Matteson, M.D., M.P.H., is Professor of Medicine and Emeritus, Division of Rheumatology in the Department of Internal Medicine at Mayo Clinic. He has a joint appointment in the Division of Epidemiology in the Department of Health Sciences Research and is faculty in the Clinical & Translational Science program at the Mayo

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Faculty

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

Graduate School. Dr. Matteson received the M.D. degree from Friedrich-Alexander University at Erlangen-Nurnberg. He completed an internship and residency in internal medicine at Michigan State University and a fellowship at the University of Michigan and received the M.P.H. degree in Public Health in Epidemiology from the University of North Carolina, Chapel Hill. Dr. Matteson’s clinical and research interests are in the fields of vasculitis and inflammatory arthritis. Dr. Matteson is the current President of the Rheumatology Research Foundation of the American College of Rheumatology.

RALF MEYER Chair, Medizinische Klinik II mit Schwerpunkt Hämatologie-Onkologie, St. Johannes Hospital, Dortmund, Germany Since May 2014, Priv. Doz. Ralf G. Meyer, MD chairs the Medical Department II at the St.-Johannes Hospital in Dortmund (Dpt. of Hematology, Oncology and Gastroenterology). He graduated at the Medical Department / Institute of the Philips-University Marburg and joined the University Medical Center Mainz as associate medical doctor in internal medicine. Dr. Meyer‘s clinical degrees in Internal Medicine as well as his qualification as specialist for Hematology and Oncology were certified at the Department of Internal Medicine III. During his tenure he joined the stem cell transplant unit which he later took over as chair. Dr. Meyer was member of cancer research groups in Immunology at the Department of Immunology in Marburg and the National Cancer Institute, Frederick, Maryland, USA. In Mainz, he further specialized in immune-response analyses and joined the “Tumor-Vaccination Center”. The research group he has established, focuses on immune-reconstitution following allogeneic

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stem cell transplantation and the role of antigen-presenting cells in graft-versus-host disease. In his current responsibility as chief medical officer of the Johannes hospital, Dortmund, Dr. Meyer mainly focusses on clinical and health service research in Hematology and Oncology. He recently founded the Center for stem-cell transplantation Dortmund, a cooperation of 3 local institutions to collaborate and excel medical care for leukaemia and lymphoma patients.

Faculty

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

SANJEEV SETHI M.D. Ph.D. Professor of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA Dr. Sanjeev Sethi graduated from Assam Medical College, India. He pursued graduate studies thereafter at Albany Medical College, NY, and received his Ph.D. in Experimental Pathology in 1995. Subsequently, Dr. Sethi completed his Clinical and Anatomic Pathology residency at Yale University School of Medicine (1995-1999). He then went on to complete his fellowship in Renal Pathology at Brigham and Women’s Hospital, Harvard University (1999-2001). He is currently a professor at the Mayo Clinic, Department of Laboratory Medicine and Pathology, Rochester. His primary interests and research are in fields of 1) Glomerulonephritis, with a focus on the approach to glomerulonephritis, the role of monoclonal gammopathy in glomerulonephritis, and the role alternative pathway of complement in glomerulonephritis, and 2) Application of proteomics in renal pathology. He has over 175 publications.

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Akademie Werbung

ULRICH SPECKS M.D. Professor of Medicine, Chair, Division of Pulmonary & Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA

Faculty

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

Dr. Specks is a graduate of the University of Bonn, Germany, Medical School, completed his Internal Medicine Residency and Pulmonary & Critical Care Medicine fellowship at the Mayo Clinic, followed by a post-doctoral fellowship in Biochemistry at the Max-Planck-Institute in Munich, Germany. He’s been on the faculty at the Mayo Clinic in Rochester, MN since 1992 and currently is Professor of Medicine at the Mayo Clinic College of Medicine and Chair of the Division of Pulmonary & Critical Care Medicine. He’s had a long-standing interest in ANCA-associated vasculitis. These diseases have been the focus of his clinical activities as well as widely published research. He’s made substantial contributions to the understanding of the pathogenesis of ANCA-associated vasculitis, the refinement of ANCA test methodologies, our understanding of optimal clinical applications of ANCA testing, as well as novel therapies for ANCA-associated vasculitis. He was the co-principal investigator of the „Rituximab for ANCA-associated Vascultitis (RAVE)“ tria

VINCENTE E. TORRES Professor of Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN, USA Vicente Torres received MD and Doctoral degrees from the University of Barcelona and moved to the Mayo Clinic in 1972 for training. He joined the faculty of the Mayo Clinic in 1979 and became Professor of Medicine in 1991 and Robert M. and Billie J. Pirnie Professor of Kidney Research in 2016. He has served as Chair of the Division of Nephrology; Director of the NIH funded Kidney Disease Research Training Grant, on the Sci-

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Faculty

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

entific Advisory Board of the PKD Foundation, and on several NIH study sections and committees. He directs the NIH funded Mayo Clinic Robert M. and Billie Kelley Pirnie Translational Polycystic Kidney Disease Center, has served as a principal investigator for the NIH funded CRISP imaging and the HALT-PKD clinical trials, and for Industry funded clinical trials of vasopressin V2 receptor antagonists. He received the 2007 Lillian Jean Kaplan Award for Advancement in the Understanding of PKD

THEODORUS XENITIDIS Rheumatology Unit, Medizinische Klinik II, Universitätsklinikum Tübingen, Germany Theodoros Xenitidis M.D., is the deputy head of the division of rheumatology in the Department of Internal Medicine II at the University Hospital Tuebingen. He was coordinating between 2011 and 2013 the Centre for Interdisciplinary Clinical Immunology, Rheumatology and Auto-inflammatory Diseases – INDIRA - at the University Hospital Tuebingen Dr. Xenitidis graduated at the Julius Maximilian University Wuerzburg and received 2012 the M.D. degree from the Eberhard Karls University Tuebingen. His clinical and research interests are about the Behcet’s Disease and arthropathies associated with Crohn’s Disease and Ulcerative Colitis.

STEVEN R. YTTERBERG Associate Professor of Medicine, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA Dr. Ytterberg is a graduate of Jefferson Medical College of Thomas Jefferson University in Philadelphia, PA. He completed Internal Medicine residency and was Chief Medical Resident at Thomas Jefferson University Hospital, followed by Rheumatology fellowship training at the

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University of Michigan. He was a member of the faculty of the University of Minnesota and the staff of the Minneapolis Veterans Affairs Medical Center before joining Mayo Clinic in Rochester, MN in 1998. He is currently an Associate Professor of Medicine at the Mayo Clinic College of Medicine. His clinical and research interests center on vasculitis and inflammatory myositis. He is a member of the steering committee of the Vasculitis Clinical Research Consortium. He has ongoing interests in medical education and has been a member of the Rheumatology Subspecialty Board of the American Board of Internal Medicine.

Faculty

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

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Sponsors

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

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SPONSORS The organizers wish to thank all sponsors for their generous support of this scientific meeting.

AbbVie Deutschland GmbH & Co. KG

Celgene GmbH

Actelion Pharmaceuticals Deutschland GmbH

GlaxoSmithKline GmbH & Co. KG

Biogen GmbH

Hexal AG

Boehringer Ingelheim Pharma GmbH & Co. KG

Janssen-Cilag GmbH

Lilly Deutschland GmbH

ORGENTEC Diagnostika GmbH

medac

Pfizer Pharma GmbH

Mundipharma Deutschland GmbH & Co. KG

Roche Pharma AG

MSD Sharp & Dohme GmbH

SWEDISH ORPHAN BIOVITRUM GmbH

Novartis Pharma GmbH

UCB Pharma GmbH

Sponsors

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

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Further information

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

FURTHER INFORMATION Do you have any questions? We are at your disposal: „„ You can access our website at: http://akademie.kk-es.de/autoimmune-conference-2017/ Here you can find the most up-to-date information so that your successful participation will not be a thing of the past. „„ Organization by: Akademie der medius KLINIKEN Charlottenstrasse 47 73230 Kirchheim unter Teck Phone: +49(0) 7021 88 44 800 Fax: +49(0) 7021 88 44 809 E-Mail: [email protected] Internet: http://akademie.medius-kliniken.de

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BEST WESTERN Hotel Am Schlossberg · Europastraße 13 · 72622 Nürtingen

Registration from BEST WESTERN Hotel Am Schlossberg in Nürtingen Please fill in completely and send to [email protected] / [email protected] or via Fax to +49 (0) 7022 704-346 Event 05.05.2017 – 07.05.2017 Kreiskliniken Esslingen gGmbH „Autoimmunity Kirchheim 2017“ Contingent number: 1164 Participant Name and Surname: Company: Adress company: Telephone number: Faxnumber: Emailadress: Room reservation: Arrival: Departure: Comment:

_______

Costs: Service accommodation 05.05. – 07.05.2017 double room incl. breakfast accommodation 05.05. – 07.05.2017 single room incl. breakfast

Rate per room EUR 105,00

needed

EUR 90,00

Invoice adress: Company name

____________________________________

Contact person

____________________________________

Adress

____________________________________

Zip code / place of residence

____________________________________

Please note that the bill must be paid directly in the hotel by check in or check out. We do not send the invoices to companies. We will use your given company address for your invoice.

Hotel Am Schlossberg GmbH & Co. KG · Tel. (07022) 7040 · Fax (07022) 704343 · [email protected] · www.hotel-am-schlossberg.de Stuttgarter Volksbank · BLZ 600 901 00 · Kto. 389 875 007 ·IBAN DE05 6009 0100 0389 8750 07 · SWIFT/BIC VOBADESS Sitz der Gesellschaft: Nürtingen · Amtsgericht Stuttgart A221669 · USt.-IdNr. DE146 261 516 · St.Nr. 74072/01846 Persönlich haftende Gesellschafterin: Hotel Am Schlossberg Verwaltungs-GmbH Nürtingen · Amtsgericht Stuttgart · HRB 221746 Vertreten durch GF Prof. Dr.-Ing. Rainer Stiefelhagen

BEST WESTERN Hotel Am Schlossberg · Europastraße 13 · 72622 Nürtingen

Booking guarantee:

This reservation is guaranteed by specifying the following credit card details:

Credit card number

____________________________________

Validity

____________________________________

Credit card holder

____________________________________

______________

reservation number

Reconfirmation Hotel

Confirmation Booker

____________________________ Name / Date Signature / Stamp

_________________________ Name / Date Signature / Stamp

BEST WESTERN Hotel Am Schlossberg GmbH & Co. KG Europastraße 13 72622 Nürtingen

Telephone: +49 (0) 7022 704-0 Telefax: +49 (0) 7022 704-346 [email protected] www.hotel-am-schlossberg.de Persönlich haftende Gesellschafterin: Hotel Am Schlossberg Verwaltungs-GmbH Nürtingen Amtsgericht Stuttgart HRB 221746

Hotel Am Schlossberg GmbH & Co. KG · Tel. (07022) 7040 · Fax (07022) 704343 · [email protected] · www.hotel-am-schlossberg.de Stuttgarter Volksbank · BLZ 600 901 00 · Kto. 389 875 007 ·IBAN DE05 6009 0100 0389 8750 07 · SWIFT/BIC VOBADESS Sitz der Gesellschaft: Nürtingen · Amtsgericht Stuttgart A221669 · USt.-IdNr. DE146 261 516 · St.Nr. 74072/01846 Persönlich haftende Gesellschafterin: Hotel Am Schlossberg Verwaltungs-GmbH Nürtingen · Amtsgericht Stuttgart · HRB 221746 Vertreten durch GF Prof. Dr.-Ing. Rainer Stiefelhagen

MULTIDISCIPLINARY APPROACH TO SYSTEMIC AUTOIMMUNE DISEASE

I would like to register for the following event: REGISTRATION FORM A171-41012 Symposium Multidisciplinary Approach to Systemic Autoimmune Disease 2017 – „Mayo Clinic Days 2017“ Date: Location: Costs: booklet included)

From Friday, May 5th, 2017, 3 pm to Sunday, May 7th, 2017, 2 pm Schlossberghalle, Dettingen, Germany  Advance Registration (until March 01st, 2017) EUR 149  Late Registration (from March 1st, 2017) EUR 190  Employee medius KLINIKEN EUR 145

EUR

Optional:

 Opt.1: Bus shuttle service (Best Western, Nürtingen - Dettingen)

EUR 40

EUR

Social program:  Get-together – dinner at Hotel Schwanen, Köngen, friday

EUR 50

EUR

EUR 10

EUR

EUR 60

EUR

EUR 10

EUR

(catering + abstract

Registration form

R E G E S T R AT I O N F O R M

Download as PDF: http://akademie.kk-es.de/autoimmune-conference-2017/

VASKULITISZENTRUM-SÜD KIRCHHEIM/TECK, GERMANY MAY 55TH – MAY – MAY 7, 2017 7TH, 2017

Included: a multi-course meal at Hotel Schwanen, Köngen. Excluded: drinks.

 Opt. 2: Extended bus shuttle service to the hotel (Dettingen - Köngen - Nürtingen)

 Meet the chairmen and speakers at Burg Teck, saturday Included: a traditional swabian meal at Burg Teck. Excluded: drinks.

 Opt. 3: Extended bus shuttle service to the parking lot and if necessary to the hotel (Dettingen - Teck - Dettingen - Nürtingen)

 Add on for people with physical limitations - „door to door“ shuttle service in order to participate in the evening event. (This service can only be used by a limited amount of people!) Total

EUR

Last name First name(s) Occupation | Function Employer Invoice to

 private

 business

Adress Town | Postcode Country Phone E-mail The terms and conditions visible in the Internet apply

Date

Signature

ORGANIZER Akademie medius KLINIKEN Charlottenstr. 47 | D-73230 Kirchheim unter Teck

[email protected] Fax +49 (0) 7021 88 44809

HOTEL (please book directly via the hotel) BEST WESTERN Hotel Am Schlossberg in Nürtingen Keyword: „Autoimmunity Kirchheim 2017“ Contingent number: 1164

More information: http://akademie.kk-es.de/autoimmune-conference-2017/ or directly to: [email protected] Fax to +49 (0) 7022 704-346

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