International Scientific Conference „New Frontiers in Biomedicine and Biotechnology“

organized by: Danube University Krems IMC University of Applied Sciences Krems on the occasion of the

- Opening of the Biotech-Laboratories/Campus Krems Nov 10-12, 2005

Under the patronage of: Dr. E. Pröll, Governor of Lower Austria Dir. F. Hölzl, Mayor of the City of Krems

Scientific program and organizing committee: Danube University Krems: D. Falkenhagen, M. Brandl, J. Hartmann, K. Hellevuo, T. Posnicek, V. Weber IMC University of Applied Sciences Krems: W. Schütt, B. Entler, H. Hundsberger, C. Kleber, R. Lucas, D. Mezricky, B. Ober

„New Frontiers in Biomedicine and Biotechnology“ Scientific Program: Nov 10, 2005 Campus Krems, Gebäude G (IMC FH Krems) 9:00

Welcome Prof. Dr. H. Kramer, Rector Danube University Krems Dkfm. Mag. H. Boyer, CEO IMC FH Krems Dir. F. Hölzl, Mayor City of Krems

3rd Life Science Meeting IMC University of Applied Sciences Krems „Modern Trends in Research, Application and Education“ 9:15

Novel Trends in Regenerative Medicine (Associated Research Topics at the IMC FH Krems)

Chairmen: Prof. (FH) Dr. W. Schütt, Programme Director Biotechnology, IMC University of Applied Sciences Krems Prof. Dr. habil. D. Falkenhagen, Head of Dept. Environmental and Medical Sciences, Danube University Krems “Dichotomal Role of TNF in Experimental Pulmonary Edema Readsorption” Prof. Dr. Rudolf Lucas, Professor at IMC FH Krems „Genomic biology and novel therapies for intracellular pathogens“ Prof. Dr. Trinad Chakraborty, Director, Institute of Medical Microbiology, Justus-LiebigUniversity, Giessen “Surfactant proteins in lung disease” Prof. Dr. Klaus Schäfer, Director Biotechnology, ALTANA-PHARMA AG, Konstanz “Development and clinical evaluation of novel cytokine-based cancer therapies” Prof. Ferdy Lejeune, Consultant DeBioPharm Lausanne, Professor Clinical Oncology, University Hospital of Lausanne

Program Part 1

International Scientific Conference

Program Part 1

“In vivo and in vitro liver injury models” Prof. Dr. Albrecht Wendel, Director, Inst. Biochem. Pharm., University of Konstanz “Protein-protein interaction – High throughput screening” Dr. Harald Hundsberger, Professor at IMC FH Krems

11:00

Coffee Break (15 min) Chairmen: Prof. Dr. Kong Deling, Nankai University, Tianjin, China Prof. Dr. Dalibor Stys, Czech Sci. Acad. Nove Hrady, CZ Dr. C. Kleber, Professor at IMC FH Krems

“Extracorporal Immunoadsorption – Basic mechanisms. Clinical applications. Strategies” Dr. Wolfgang Ramlow, Head of Dialysegem. Nord e.V., Rostock “Polymers for tissue engineering” Prof. Dr. Kong Deling, Head of Chinese Key Lab. Bioactive Materials, Nankai University, Tianjin, China “Collagen in tissue engineering: Regulation of fibril formation in vitro and in vivo” Prof. Dr. Holger Notbohm, Institut für Medizinische Molekularbiologie Universität Lübeck „Testing of bioactivity of algal molecules“ Prof. Dr. Dalibor Stys, Director Inst. Phys. Biol., Czech Sci. Acad. Nove Hrady, Czech Republic “Cellular therapy” Georg Steiner, Director, Cell Danube AG, Krems

12:30

Lunch Buffet

13:30

Current Industrial and Basic Research fields of the IMC FH Krems Partners for Student Practical Training Chairman: Prof. Dr. Günter von Sengbusch, former Director Großforschungszentrum GKSS der Helmholtz Gemeinschaft Deutscher Forschungszentren, Hamburg Dr. B. Ober, Professor at IMC FH Krems

“Development of recombinant biotherapeutics” Dr. Roman Necina, Head of Production, BOEHRINGER Ingelheim, Vienna “Targeting memory Th2 cells for the treatment of allergic asthma” Prof. Dr. Michelle Epstein, Department of Dermatology, Vienna “In vitro models of bone resorption-applications” Prof. Dr. Hofmann, Dept. Pharmacology & Toxicology, Medical University of Vienna, „Trends in research of pathogen safety“ Dr. Thomas Kreil, Director Global Pathogen Safety, BAXTER Bioscience AG, Vienna

“Mini-Bioreactors” Dr. Eric Gottwald, Project Leader Forschungszentrum Karlsruhe “Exploring signal transduction pathways as potential therapeutic targets in lymphoid leukaemia” Prof. Dr. Veronica Sexl, Dept. Pharmacology, Meduni Wien “Recombinant antibody technologies” Dr. Ralf Ostendorp, Head of Research, MorphoSys AG, Munich

16:10

16:45

Coffee Break

and meeting of Practical Training partners with students Moderation: Dr. B. Ober, Professor at IMC FH Krems and Practical Training Coordinator

Key Note Speech Chairman: Prof. Dr. R. Lucas, Professor at IMC FH Krems

“Mechanisms of compromised ion transport by pathogens and viruses” Prof. Dr. Sadis Matalon, Alice McNeal Professor of Anesthesiology, Professor of Physiology and Biophysics, Microbiology and Environmental Health Sciences, University of Alabama at Birmingham, US

17:15

Round Table Discussion:

(in German)

Introduction: Prof. (FH) Mag. H. Lichtenwagner, Dean IMC FH Krems Prof. (FH) Dr. W. Schütt, Programme Director Biotechnology, IMC FH Krems Prof. Dr. G. von Sengbusch, former Director GKSS, Hamburg

„Wird das FH Ausbildungskonzept den Anforderungen der Praxis gerecht?“ Moderation: Dr. U. Schlokat Head of Global Projectmanagment, Baxter Healthcare Cooperation, Westlake Village / Wien Prof. Dr. J. Vienken Vice President Bioscience Dept., Fresenius Medical Care, Bad Homburg Dr. B. Entler Professor at IMC FH Krems

Program Part 1

“Trends in blood plasma research” Dr. Volker Weimar, Head of Production, OCTAPHARMA AG, Vienna

Program Part 1

Teilnehmer: Prof. Dr. Michelle Epstein Dept. of Dermatology, Medical University Vienna Dr. Thomas Kreil Director Global Pathogen Safety, BAXTER Bioscience, Vienna Dr. Roman Necina Head of Production, BOEHRINGER Ingelheim, Vienna Dr. Eric Gottwald Project Leader Forschungszentrum Karlsruhe Prof. Dr. Veronica Sexl Dept. Pharmacology, Medical University Wien Mag. G. Kämpf Head of Pharma Economy, Sanofi-Aventis, Wien Dr. Katharine Cohen, EP attorney Head of Intelectual Properties and Licensing, InterCell AG, Vienna, Austria Dr. Ralf Ostendorp Head of Research, Morphosys Ag, Munich Dr. Volker Weimar Head of Production, OCTAPHARM, Vienna

19:30

Heurigenabend

Tagungsteilnehmer mit allen Biotechnologiestudenten der IMC FH Krems

Nov 11, 2005 9:00 - 12:00 Wissenschaftliches Programm der Donau Universität Krems (siehe Part 2) 12:30

Gemeinsame Veranstaltung der Mitarbeiter und Biotechnologie-Studierende der IMC FH Krems mit Gästen Dkfm. Mag. H. Boyer, Geschäftsführer IMC FH Krems Prof. (FH) Mag. H. Lichtenwagner, Rektor (FH) IMC FH Krems „Vernetzung von Naturwissenschaften, Medizin und Industire“ Prof. Dr. Günther von Sengbusch, em. Dekan Großforschungszentrum GKSS der Helmholz Gemeinschaft deutscher Forschungszentren, Hamburg „Im Banne der Königin der tropischen Pflanzen“ Prof. Dr. em. Ingolf Lamprecht, em. Dekan der Freien Universität Berlin

15:00

Fortsetzung des Wissenschaftlichen Programms der Donau Universität Krems (siehe Part 2)

Danube University Krems

„New Technologies in Medicine“ A joint Meeting of the Department of Mechanical Engineering, Stanford University and C. Doppler Laboratory for Specific Adsorption Technology in Medicine at the Danube University Krems Nov 11 - 12, 2005 Location: Campus Krems, Austria Nov. 11: Gebäude G, IMC FH Krems Nov. 12: Gebäude E, Österreichische Filmgalerie

Program Part 2

Scientific Symposium

Program Part 2

Scientific Program 8.30

Welcome Addresses:

Dir. Franz Hölzl, Mayor of the City of Krems Prof. Ada Pellert, Vice Rector of Danube University Krems Prof. Dr. F. B. Prinz, Chairman of Mechanical Engineering, Stanford University Prof. Dr. D. Falkenhagen, Head of Department of Environmental and Medical Science, Danube University Krems Prof. (FH) Dr. W. Schütt, Program Director Biotechnology, IMC University of Applied Sciences Krems

Nov 11, 2005 Campus Krems, Gebäude G (IMC FH Krems) 9.00 – 10.45

Regenerative Medicine/Tissue Engineering Chair: F. B. Prinz, D. Falkenhagen

09.00 A. Bader

New Technologies in Regenerative Medicine

09.20 G. Wick

Antiaging Medicine: Facts or Fiction

09.40 B. H. Walpoth Vascular Tissue Engineering 10.00 M. Nerlich

Tissue Engineering of Bone Defects

10.15 P. Angele

Tissue Engineering in Cartilage

10.30 S. Nehrer

Tissue Engineering in Orthopedic Surgery

10.45 – 11.00

Coffee Break

11.00 – 12.15

Regenerative Medicine/Organ Support Chair: M. Nerlich, V. Weber

11.00 K. Hellevuo, V. Weber Importance of interactive cell culture systems for sepsis diagnostics and therapy 11.20 S. Pokrovsky Therapeutic apheresis and adsorption technologies: contribution of Russia 11.35 G. Philips

Polymers for extracorporeal carbon devices

11.55 J. M. Braun

Tolerance induction in organ transplantation

12.15 – 15.00

Break - Special Birthday – Session – Prof. Schütt

12.15 H. Kramer

Official Opening of the laboratories of the Department for Clinical Medicine & Biotechnology

15.00 – 16.30

Nanotechnology Chair: G. Wick, T. M. S .Chang

15.00 M. Sàra

Principles of nanobiotechnologies

15.20 F. B. Prinz

Electron transport from ferredoxin to FNR or to nanoscale electrodes

16.05 A. Robitzki

Nanostructures on microarrays for a real time monitoring of living cells and tisssues

16.25 E. Piskin

Nanostructured Biomaterials

16.45 – 17.00

Coffee Break

17.00 – 18.00

Round Table Discussion Science in the conflict of Politics and Business

Moderation: Dietmar Zeiss, Chief Editor Pressetext Austria Participants: Dr. A. v. Gabain, Intercell Dr. E. Gatti, Fresenius Medical Care AG Prof. U. Gornik, ARC Seibersdorf Prof. F. B. Prinz, Stanford University Prof. G. Wick, Med. University Innsbruck MR Mag. Pasterk, Ministry of Education, Culture and Science, Vienna Representative of the Lower Austrian Government 19.00

Welcome Reception by the Mayor of Krems & Heurigen Event

Nov 12, 2005 Location: Cinema of „Österreichische Filmgalerie“ 08.30 - 10.15

Regenerative Medicine/Tissue Engineering & Scaffolds Chair: J. Kirkpatrick, R. L. Reis

08.30 R. L. Reis

Organizing the European Center of Excellence in Tissue Engineering Expertissues

08.45 J. Kirkpatrick Biocompatibility Testing in the Context of Tissue Engineering 09.05 R. L. Reis

New Strategies for Tissue Engineering of Bone

09.25 W. Ryu

Creation of micro-geometries in 3D biodegradable polymers for tissue scaffolds and drug delivery

09.45 S. Mikhalovsky Polymers as biomaterials/Extracorporeal carbon devices 10.00 T. Groth

Development of temporary carriers for tissue engineering of skin

10.15 – 10.30

Coffee Break

10.30 – 12.30

Regenerative Medicine/Cell Therapy Chair: J. Huber, G. Schmitz

10.30 J. Huber

Possibilities of Cell Therapy

10.50 G. Steinhoff

Stem Cells in therapy of heart infarction

11.10 W.H. Günzburg An Encapsulated Allogenic Cell Product for the treatment of pancreatic cancer

Program Part 2

15.40 T. M. S. Chang Blood Substitutes: from molecular biotechnology to nanobiotechnology

Program Part 2

11.30 – 11.45

Coffee Break

11.45 G. Schmitz

Mesenchymal stem cells in regenerative medicine

12.10 L. Germeroth Streptamers-reversible MHC Multimers for adoptive T-cell transfer Special Lecture 12.30 H. Kurz

EC-Regulations for Biologicals

12.50

Closing Remarks

13.00

Lunch & End of Meeting

List of Participants of the Round Table Discussion:

Dr. A. v. Gabain, CEO Intercell, Vienna, Austria Dr. E. Gatti, Management Board Fresenius Medical Care AG, Bad Homburg, Germany Prof. E. Gornik, CEO ARC Seibersdorf, Austria Prof. F. B. Prinz, Chairman of Department of Mechanics, Stanford University, USA Prof. G. Wick, Head of Inst. for Pathophysiology, Med. University Innsbruck, Austria MR Mag. Pasterk Ministry of Education, Science and Culture, Vienna, Austria Representative of the Lower Austrian Government

List of Chairmen and Speakers: Chairmen:

Prof. T. M. S. Chang, Head of Department of Physiology, Mc Gill University, Montreal, Canada Prof. D. Falkenhagen, Head of Department of Medical and Enviromental Sciences, Danube University Krems, Austria Prof. J. Huber, Head of Department for Gynaecological Endocrinology, AKH Vienna, Austria Prof. J. Kirkpatrick, Head of Inst. of Pathology, Johannes Gutenberg University Mainz, Germany Prof. S. Mikhalovsky, Head of Material Research Group, University of Brighton, UK Prof. Dr. F. B. Prinz, Chairman of Department of Mechanics, Stanford University, USA Prof. Dr. G. Schmitz, Director of Institute of Clinical Chemistry, University of Regensburg, Germany Prof. R. L. Reis, Head of European Competence Center of Regenerative Medicine, Univ. of Minho, Portugal Dr. Viktoria Weber, C. Doppler Lab for Spec. Adsorption Technology in Medicine, Danube University Krems

Speakers: PD Dr. P. Angele, Department of Emergency Surgery, University of Regensburg, Germany Prof. Dr. A. Bader, Head of Institute for Cellular Technology and Applied Stemcell Biology, University of Leipzig, Germany Dr. J. M. Braun, Department of Clinical Immunology, University Leipzig, Germany Prof. T. M. S. Chang, Head of Department of Physiology, Mc Gill University, Montreal, Canada Dr. L. Germeroth, CEO IBA GmbH, Göttingen, Germany Prof. T. Groth, Prof. for Tissue Engineering, University Halle, Germany Prof. W. H. Günzburg, Head of Institute of Virology, University of Veternary Medicine, Vienna, Austria Dr. Kaisa Hellevuo, C. Doppler Lab for Spec. Adsorption Technology in Medicine, Danube University Krems Prof. J. Huber, Head of Department for Gynaecological Endocrinology, AKH Vienna, Austria Prof. J. Kirkpatrick, Head of Inst. of Pathology, Johannes Gutenberg University Mainz, Germany Prof. S. Mikhalovsky, University of Brighton, School of Pharmacy and Biomolecular Sciences, UK Prof. M. Nerlich, Dean of Medical Faculty & Head of Dept. of Emergency Surgery, Regensburg, Germany Prof. S. Nehrer, Medical University of Vienna, Orthopaedic Department & Center for Tissue Engineering, Danube University Krems, Austria Prof. G. Phillips, University of Brighton, School of Pharmacy and Biomolecular Sciences, UK Prof. E. Piskin, Head of Inst. Of Bioengineering, Hacettepe University Ankara, Turkey Dr. S. Pokrovsky, Institute of Experimental Cardiology, Moscow, Russia Prof. F. B. Prinz, Chairman of the Department of Mechanical Engineering, Stanford University, USA Prof. R. L. Reis, Head of European Competence Center of Regenerative Medicine, Univ. of Minho, Portugal Prof. Andrea Robitzki, Head of Division of Molecularbiolog.-Biochem. Processing Tech., Univ. Leipzig, Germany Dr. W. Ryu, Department of Mechanical Engineering, Stanford University, USA Prof. Margit Sàra, Centre of Ultrastructure Research, Univ. of Natural Resources & Applied Life Sc., Vienna, Austria Prof. G. Schmitz, Chairman of Clinical Chemistry, University of Regensburg, Germany Prof. G. Steinhoff, Head of Department for Cardiosurgery, University Rostock, Germany Dr. B. H. Walpoth, Director of Cardiovascular Research, University Hospital Geneve, Swizerland Dr. Viktoria Weber, C. Doppler Lab for Spec. Adsorption Technology in Medicine, Danube University Krems, Austria Prof. G. Wick, Head of Inst. for Pathophysiology, Med. University Innsbruck, Austria

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How to find the Campus Krems

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