Injection: Epidural Steroid (Cervical)

Evidence Table: Injection: Epidural Steroid (Cervical) Injection: Epidural Steroid (Cervical) Evidence of effectiveness 1 experimental study (1 inclu...
Author: Allan Tyler
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Evidence Table: Injection: Epidural Steroid (Cervical)

Injection: Epidural Steroid (Cervical) Evidence of effectiveness 1 experimental study (1 included)

~

Evidence of safety and harm 6 additional studies

Generic legend: n/a - not applicable n/s - not stated n/r - not relevant ? - unsure or unclear

1

Evidence Table: Injection: Epidural Steroid (Cervical)

Experimental Study study authors and year

participants

study inclusion/ exclusion

exposure/ comparison

outcomes

results

validity / applicability

yes no n/a n/s

conclusions, comments, and quality scores

42 patients

Inclusion: Chronic refractory cervicobrachialgia, clinical or radiological signs of pathology in the C4-C7 region.

Exposure: 25 patients received cervical epidural Injection: Tuohy needle inserted via a midline approach into the C5/C6 or the C6-C7 interspace. Using the loss of resistance to air technique, 80mg (2ml) methylprednisolone sodium acetate and 5ml of lignocaine were injected. Procedure repeated at 2-week intervals according to individual response for a maximum number of three injections

Pain relief; Daily dose analgesics; Recovery of capacity to work; Range of movement; Sensory and motor deficits

“Very good” and “good” Pain relief at one week after last injection: 1 year: 76% of patients in cervical epidural group vs. 35.2% in intramuscular injection group (p=0.0377) 1 year: Cervical epidural group 68%, intramuscular injection 11.8% (p=0.0004)

Randomised Method described Similar at baseline Concealment Intention to treat Blinding appropriate Single blind Double blind Blind outcome assessment Compliance OK Follow-up OK Drop outs

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