INJECTING INNOVATION INTO HEALTH CARE

Medical Devices Packaging Drug Delivery Systems

ARaymondlife applies its technological expertise to the development and manufacture of innovative solutions for the health care industry. As a partner of medical laboratories and other players in the medical diagnostics sector, ARaymondlife provides assistance throughout the entire product life cycle. As a solutions provider, we turn your ideas into customised innovations.

RayDyLyo RayDyLyo is a closure device for standard vials1 and an all-plastic capping solution. RayDyLyo provides an alternative to aluminium, eliminating the crimping step for liquid and freeze-dried forms. It provides an ergonomic advantage through ease of opening and reduced risk of glove damage.

1- Standards iso 8362-1 and 8536-1

THE EXPERT IN PLASTIC MANUFACTURING YOUR PARTNER IN HEALTH CARE PROJECTS

MEDICAL DEVICES ARaymondlife* conceives and manufactures medical devices, notably single-use devices and plastic accessories for disease diagnostics and prevention.

PACKAGING ARaymondlife designs and develops technical solutions as well as components for pharmaceutical packaging, which include both custom and industry standards.

DRUG DELIVERY SYSTEMS In partnership with a French veterinary laboratory, ARaymondlife has developed a drug delivery system for hormones administered through an impregnated matrix.

ENGINEERING

AND CUSTOM SOLUTIONS

PHARMACEUTICAL

ESTABLISHMENT

Through its in-house research division, ARaymondlife provides start-to-finish services for development projects, from initial concepts to production runs: understanding of customer needs, definition of technical specifications, design studies, prototyping, simulation methods and rheology. Our engineers are constantly creating new concepts from our continuous research into new materials and technologies to provide innovative and cost-effective technical solutions. As a GMP EU certified pharmaceutical manufacturer, ARaymondlife is equipped with automated industrial equipment for manufacturing in a controlled atmosphere, including: • Clean rooms • Workshops dedicated to drug manufacturing • Medicalised presses

THE EXPERT

IN PLASTIC INJECTION MOULDING ARaymondlife applies its expertise in thermoplastic, silicone injection and bi-injection (LSR); developed by the ARaymond Network for the pharmaceutical industry. • Expertise in polymers: medical grades, high mechanical and optical performances • Expertise in processes: mono or bi-material injection, overmoulding, automated complex assembly, ultrasound and laser welding • Customisation: marking and laser engraving, personalized colours • Additional services: washing, sterilisation, custom packaging

Polymers releasing an active substance ARaymondlife assists pharmaceutical laboratories in developing solid galenic forms such as impregnated matrices, throughout the entire life cycle of the medicine, from clinical trials to product launch, including polymer selection, pharmacokinetics research, matrix creation, and defining the mode of administration.

The ARaymond Network** With over 150 years of experience, ARaymond Network, the expert in plastic injection moulding, metal transformation and assembly, invents, manufactures and commercialises fastening solutions for the automobile industry. Since 2007, ARaymondlife has been applying this expertise to the health care industry.

22 production sites worldwide

5,000

Lyon

men and women make up the richness and diversity of the ARaymond Network

Genêve

Grenoble

1,000 25,000

products in production

ARaymondlife, a member of the ARaymond Network, is based in Grenoble, in the heart of the Rhône-Alpine region, in close proximity to leading pharmaceutical research and industrial centres, including world leaders in the fields of human vaccines, biotechnology, animal health, and in vitro diagnostics.

© Raygroup SASU * "ARaymondlife" is the business name of ARaymondlife SASU – RCS Grenoble 501 397 012 – Rue de la Louisiane - 38120 Saint Egrève – FRANCE, an independent company of the ARaymond Network, and the entity responsible for this Brochure. ** "ARaymond Network" refers to a network of independent companies authorised to use the same trademark. "Brochure" refers to the information and elements contained in this brochure, including, but not limited to, all text, numbers, illustrations, data sheets, product descriptions, etc. ARAYMOND™ is a registered trademark. This Brochure does not constitute an offer or contractual agreement of any kind. This Brochure does not constitute a technical data sheet. This Brochure is provided "as is" and for evaluation purposes only. ARaymondlife makes no guarantee or claim whatsoever as concerns this Brochure, its use, or its suitability to specific needs. ARAYMONDLIFE MAKES NO GUARANTEE, EXPLICIT OR IMPLICIT, INCLUDING, BUT NOT LIMITED TO, AS TO THE ACCURACY, RELIABILITY, NOVELTY, COMPLETENESS, MARKET VALUE OR SUITABILITY TO ANY USE WHATSOEVER, OF ANY OF THE INFORMATION CONTAINED HEREIN, OR AS TO THE FACT THAT THEIR USE DOES NOT VIOLATE THE RIGHTS OF ANY THIRD PARTY. ARaymondlife shall not be held liable for any indirect, consequential or special damages whatsoever which may arise from the use of this Brochure. All rights not expressly granted herein are reserved. Unless otherwise expressly stated herein, nothing in this Brochure may be interpreted as granting any license or right whatsoever to any copyright, patent, property right or brand. Any unauthorised use of this Brochure may be considered a violation of rights, which may lead ARaymondlife or any concerned third party to claim damages or reparations of loss suffered as a result of said use. For further information, please contact ARaymondlife.

ARAYMONDLIFE SASU Rue de la Louisiane - 38120 Saint-Egrève FRANCE Tél. + 33 4 56 52 53 36 Email : [email protected]

NF EN ISO 13485

ISO 15378

ISO 9001

www.raydylyo.com www.araymond-life.com

2014/04 Photo: Franck Ardito, ARaymond Network Library

active patents

YOUR PARTNER IN MEDICAL DEVICE PROJECTS

ARaymondlife* is a pharmaceutical establishment with expertise in plastic injection molding. ARaymondlife* leans on its technological expertise for the development and the production of solutions dedicated to the market of medical devices.

CUSTOM-MADE SUPPORT ))) Multidisciplinary team stemming from Healthcare Industry ))) Integrated R&D department

Creativity Proximity Reactivity

))) Production batch size from small to large series ))) Project management and support throughout your project

))) PRODUCT DESIGN PROCESS Serial production

Dedicated production workshops

5

Development of user requirement specifications

Project analysis and formalization

4

1

3 2 Design and 3D-modeling

Prototype

Pre-serial phase validation

Brainstorming solutions

OUR EXPERTISE IN MEDICAL DEVICE DESIGN IS APPLIED TO THE FOLLOWING SPECIALTIES: ))) In vitro diagnostics ))) Dental ))) Medical imaging ))) Orthopedics ))) Animal health

Industrialization Mold and tool optimization

YOUR PARTNER IN MEDICAL DEVICE PROJECTS

ARAYMONDLIFE, INJECTING INNOVATION INTO HEALTHCARE Plastic injection molding

Single and dual plastic injection molding, silicone LSR, duplicate molding

Raw materials

Medical grade raw materials, alimentary grades, thermoplastics and silicone

Levels of precision

Micro-fluidics, optical quality, waterproof

Customization

Colors, engraving, labeling

Assembly

Mechanical assembly, ultrasound & laser welding

Packaging

Unitary packaging, multiple and customized packaging

Cleanliness

ISO 7 clean rooms, washing and sterilization

APPLICATION OF OUR KNOW-HOW* BI-MATERIAL INJECTION

TRANSPARENT RAW MATERIAL HIGH OPTICAL PROPERTIES

INSERTION OF REAGENTS

ERGONOMIC DESIGN

ERGONOMIC DESIGN

TECHNICAL ASSEMBLY

* Example of single use medical device

© Raygroup SASU * «ARaymondlife» is the business name of ARaymondlife SASU – RCS Grenoble 501 397 012 – Rue de la Louisiane - 38120 Saint Egrève – FRANCE, an independent company of the ARaymond Network, and the entity responsible for this Brochure. ARaymond™ is used as a trademark. «Product sheet» refers to the information and elements contained in this Product sheet, including, but not limited to, all text, numbers, illustrations, data sheets, product descriptions, etc. ARAYMOND™ is a registered trademark. This Product sheet does not constitute an offer or contractual agreement of any kind. This Product sheet does not constitute a technical data sheet. This Product sheet is provided «as is» and for evaluation purposes only. ARaymondlife makes no guarantee or claim whatsoever as concerns this Brochure, its use, or its suitability to specific needs. ARaymondlife makes no guarantee, explicit or implicit, including, but not limited to, as to the accuracy, reliability, novelty, completeness, market value or suitability to any use whatsoever, of any of the information contained herein, or as to the fact that their use does not violate the rights of any third party. ARaymondlife shall not be held liable for any indirect, consequential or special damages whatsoever which may arise from the use of this Product sheet. All rights not expressly granted herein are reserved. Unless otherwise expressly stated herein, nothing in this Product sheet may be interpreted as granting any license or right whatsoever to any copyright, patent, property right or brand. Any unauthorized use of this Product sheet may be considered a violation of rights, which may lead ARaymondlife or any concerned third party to claim damages or reparations of loss suffered as a result of said use. For further information, please contact ARaymondlife. LI2014-1002-EN_DM (10/2014)

ARAYMONDLIFE SASU Rue de la Louisiane 38120 Saint-Egrève - FRANCE Tel. + 33 4 56 52 53 36 Email : [email protected]

NF EN ISO 13485

ISO 15378

ISO 9001

www.araymond-life.com