Hematopathology Symposium

REGISTRATION (Please Print): n Practicing Physicians n Honorary Physicians n UHS Nurses/Staff n Non-UHS Nurses/Staff n Residents/Students $80 $35 $3...
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REGISTRATION (Please Print): n Practicing Physicians n Honorary Physicians n UHS Nurses/Staff n Non-UHS Nurses/Staff n Residents/Students

$80 $35 $30 $40 $0

CREDIT DESIGNATION: SUNY Upstate Medical University designates this live activity for a maximum of 7.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

UHS in conjunction with Broome Oncology present

11th Annual Hematology/ Hematopathology Symposium

DISCLOSURE POLICY: To ensure balance, independence, objectivity, and scientific rigor in all certified CME activity SUNY Upstate Medical University requires that all planners, faculty and individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest that might be perceived as a real or apparent conflict of interest. Detailed disclosures will be made in writing prior to speaker presentations.

ADDRESS STATE

ZIP

E-MAIL DAY PHONE

n Will also attend May 20, Educational Dinner Pgm

PAYMENT OPTIONS: n Checks payable to: UHS CPE Department n Charge to my credit card: n Visa n Master Card n AmEx n Discover Account# Exp. Date: Signature: n UHS employees may pay: I have authorized the registrant to attend this Teaching Day as a UHS employee. I authorize UHS to bill my: Cost Center _________________ for $___________ Mgr. Signature ______________________ Mgr. Phone _____________________ Mail/Fax Registration Form To:

UHS Wilson Medical Center Department of Pathology, Attn: Tracie Bird 33–57 Harrison Street, Johnson City, NY 13790 Fax: (607) 763-5252 Enrollment is limited. Registration and payment is due by May 6, 2016. After that date, add $5 for late processing fee. Registrations may be verified by calling (607) 763-6285.

Saturday, May 21, 2016 8:00am – 5:00pm

AMERICANS WITH DISABILITIES ACT (ADA): In accordance with the Americans with Disabilities Act, SUNY Upstate Medical University seeks to make this conference accessible to all. If you have a disability which might require special accommodations, please contact Tracie Bird (607) 763-6285.

Beyond Morphology: Phenotypic & Genetic Predictors of Clinical Behavior in B-Cell Lymphoma

REFUNDS and VERIFICATION: A full refund of your registration fee is available with written cancellation on or before May 6, 2016. After May 6th there is a $10.00 processing fee. HOTEL Reservations: A block of rooms will be held at a special conference rate of $149.00 for a single or double room. Note: This rate is only good until April 28, 2016. A room can be reserved by calling Sheraton Syracuse University at (800) 395-2105. Be sure to reference the “H/H 2016 Symposium” to get the discounted rate. There is a $13.00 charge per day for hotel parking.

A Symposium

Keynote Speaker Ahmet Dogan, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, NY

DIRECTIONS to SHERATON SYRACUSE UNIVERSITY HOTEL: From Syracuse Hancock International Airport and points North: Take Interstate 81 South to Exit 18 (Adams Street). Bear left and go to the 2nd light. Turn left on East Adams. At the 4th light turn right on University Avenue. The hotel is 2 blocks on the left. From Albany, NY and points East: Take Interstate 90 to Exit 34A. Take 481 South to 690 West to the Teall Avenue Exit. Turn left onto Teall and go to the 2nd light. Turn right onto Erie Boulevard East and then left onto University Avenue. Go for 7 blocks and the hotel will be on the left. From Buffalo, NY and points West: Take Interstate 90 East to Exit 39. Take 690 East to 81 South and take Exit 18 (Adams Street). Follow the signs to Adams Street and then turn left onto Adams. At the 4th light, turn right onto University Avenue. The hotel will be on the left. From New York City: Take Route 17 to Binghamton. Take I-81 North to Syracuse and then take Exit 18 (Harrison/Adams Street). Turn right on East Adams Street. Go to the 4th traffic light and turn right onto University Avenue. Hotel is two blocks on the left. From points South: Take 81 North to Exit 18 (Harrison/Adams Street). Turn right onto East Adams Street. Go to the 4th traffic light and turn right onto University Avenue. Hotel is two blocks down on the left. UHS/LS/06/03/16/7C

Address Service requested

ORGANIZATION

Tracie Bird, Dept. of Pathology UHS Wilson Medical Center 33–57 Harrison Street Johnson City, New York 13790

NAME/TITLE

CITY

ACCREDITATION: This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of SUNY Upstate Medical University and United Health Services. SUNY Upstate Medical University is accredited by the ACCME to provide continuing medical education for physicians.

Non-Profit Organization U.S. Postage PAID Binghamton, NY Permit No. 175

Hematology/Hematopathology Symposium

Friday, May 20, 2016 6:00pm – 10:00pm

Note: Register for the symposium online at uhs.net/HHSymposium

Educational Dinner Program Sponsored by Genoptix (Non-CME Activity)

Sheraton Syracuse University Hotel & Conference Center Syracuse, NY

Program Coordinators

Hematology/Hematopathology Symposium INTENDED AUDIENCE The faculty will speak to the educational needs of the hematologists, oncologists, pathologists, hematopathologists, pathology and internal medicine residents and fellows, medical students, students in biology-related studies, hematology and flow cytometry technologists, physician assistants, nurse practitioners, and nurses.

Faculty continued Elizabeth Ruckdeschel, MD, PhD Assistant Professor, Dept of Pathology, SUNY Upstate Medical University, Syracuse, NY Jagmohan Sidhu, MD Director & Chairman of Pathology, UHS Hospitals, Johnson City/Binghamton, NY

Agenda continued Ramona Vesna Untanu, MD Hematopathology Fellow, SUNY Upstate Medical University, Syracuse, NY Gang Yue, MD, PhD Hematopathologist, UHS Hospitals, Johnson City/Binghamton, NY

Agenda for FRIday EVENING (May 20, 2016) Non-CME Activity

Keynote Speaker

Location: Comstack A Conference Room

Ahmet Dogan, MD, PhD Chief of Hematopathology Memorial Sloan Kettering Cancer Center, New York, NY

6:00pm Reception 7:00pm Genomic Profiling of Non-Hodgkin Lymphoma: Examples and Comparison to Traditional Testing Technologies Bashar Dabbas, MD, Medical Director, Genoptix Medical Laboratory, Division of Novartis 8:00pm Dinner

Faculty John Astle, MD, PhD Hematopathology Fellow, Yale University, New Haven CT Katalin Banki, MD Associate Professor of Pathology, SUNY Upstate Medical University, Syracuse, NY Abaigail Bird Pre-Medical Student, Utica Collage, Utica, NY W. Richard Burack, MD, PhD Director of Hematopathology, University of Rochester, Rochester, NY George Deeb, MD Director of Flow Cytometry, Emory University Hospital, Atlanta, GA Andrew Evans, MD, PhD Assistant Professor, Dept. of Pathology, University of Rochester, Rochester, NY Robert Hutchison, MD Director of Clinical Pathology, SUNY Upstate Medical University Syracuse, NY Serazul Khan, MD Hematologist & Oncologist, UHS Oncology, Johnson City, NY

Shridevi Karikehalli, MD Director of Hematopathology, Centrex Clinical Laboratories, Utica, NY Hani Katerji, MD Pathology Resident, University of Rochester, Rochester, NY Mihai Merzianu, MD Associate Professor, Dept of Pathology Roswell Park Cancer Institute, Buffalo, NY Tipu Nazeer, MD Director of Surgical Pathology & Hematopathology, Albany Medical Center, Albany, NY Vishala Neppalli, MD Assistant Professor, Dept of Pathology, Roswell Park Cancer Institute, Buffalo, NY Narendra Panesar, MD Pathologist, UHS Hospitals Johnson City/Binghamton, NY Nisha Patel, MD Hematopathology Fellow, University of Rochester, Rochester NY Danielle Robinson, DO Medical Student, UHS Hospitals Johnson City/Binghamton, NY

Agenda for SYMPOSIUM (May 21, 2016) 7:30am Registration Cheryl Connoly, Lindsey Bird and Tracie Bird 8:00am Welcome & Introductions James Hayes, MD 8:10am Pre-test 8:20am Keynote Lecture: Beyond Morphology: Phenotypic and Genetic Predictors of Clinical Behavior in B-Cell Lymphoma Ahmet Dogan, MD, PhD 9:20am Case Study: Indolent B-Cell Lymphoma with Aggressive Features W. Richard Burack, MD, PhD 9:32am Case Study: Large B-Cell Lymphoma with Unexpected Indolent Behavior Andrew Evans, MD, PhD 9:44am Case Study: Gray Zone Lymphoma with Features in Between Classic Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Mihai Merzianu,MD 9:56am Case Study: De Novo Large B-Cell Lymphoma with Morphologic Features Suggesting More Aggressive Behavior Vishala Neppalli, MD 10:08am Coffee Break 10:23am Case Study: Diffuse Large B-Cell Lymphoma with Triple Hit Tipu Nazeer, MD 10:35am Case Study: Intravascular Large B-Cell Lymphoma with a Complex Karyotype Katalin Banki, MD

10:47am DOUGLAS NELSON LECTURE: Epigenetic Predictors of Clinical Behavior in B-Cell Lymphoma Robert Hutchison, MD 11:30am SPECIAL LECTURE: Flow Cytometric Predictors of Clinical Behavior in B-Cell Lymphoma George Deeb, MD 12:10pm De Novo Large B-Cell Lymphoma with Molecular Features Suggesting More Aggressive Behavior Elizabeth Ruckdeschel, MD, PhD 12:22pm Lunch Break 1:20pm Case Study: Burkitt Lymphoma with Atypical Features Nisha Patel, MD 1:32pm Case Study: Indolent B-Cell Lymphoma with Aggressive Features Hani Katerji, MD 1:44pm Case Study: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Accelerated Type Gang Yue, MD, PhD 1:56am NEXT-GENERATION PATHOLOGY LECTURE: Improving Quality and Structure of Big Data in Pathology John Astle, MD, PhD 2:30pm Case Study: Intrafollicularly Transformed Follicular Lymphoma Showing Blastoid, Not Large Cell, Transformation Narendra Panesar, MD 2:42pm Case Study: Diffuse Large B-Cell Lymphoma Co-Expressing MYC & BCL2 and Showing MYC & BCL6 Translocations Ramona Vesna Untanu, MD 2:54pm Coffee Break 3:10pm Case Study: CD5-Positive Diffuse Large B-Cell Lymphoma Showing Extensive Sinusoido-Angiotropism Danielle Robinson, DO 3:22pm Case Study: CD5-Positive Intravascular Large B-Cell Lymphoma Abaigail Bird 3:32pm Case Study: CD15-Positive Intravascular Large B-Cell Lymphoma Shridevi Karikehalli, MD 3:44pm Case Study: ALK-Positive Diffuse Large B-Cell Lymphoma Showing Angiotropism Jagmohan Sidhu, MD 3:56pm HEMATO-ONCOLOGY LECTURE: Current and Emerging Therapies for B-Cell Lymphomas with Expected and Unexpected Clinical Behavior Serazul Khan, MD 4:46pm Post-Test / Take-Home Messages / Adjournment Jagmohan Sidhu, MD and Serazul Khan, MD **For a CME Certificate all completed evaluations and pre/post tests must be turned in at the registration desk.

Ronald Harris, DO Jagmohan Sidhu, MD James Hayes, MD Tracie Bird Cheryl Connolly Program objectives Recognize morphologic and immunophenotypic features that predict unexpected behavior of B-cell lymphomas. Recognize genetic and epigenetic features that predict unexpected behavior of B-cell lymphomas. Describe current and emerging therapies for B-cell lymphomas based on their predicted clinical behavior. acknowledgements UHS/UHS Medical Group and Broome Oncology are grateful to the pharmaceutical and laboratory technology industries for their generous unrestricted educational support of this continuing education program. A full list of contributors will be included in the meeting syllabus. mission UHS is a comprehensive regional health system whose mission is to improve the health of those we serve through our commitment to excellence in all that we do. vision UHS, the region’s leading integrated healthcare system, will demonstrate exceptional value in the delivery of coordinated, patient-centered care.

Program Coordinators

Hematology/Hematopathology Symposium INTENDED AUDIENCE The faculty will speak to the educational needs of the hematologists, oncologists, pathologists, hematopathologists, pathology and internal medicine residents and fellows, medical students, students in biology-related studies, hematology and flow cytometry technologists, physician assistants, nurse practitioners, and nurses.

Faculty continued Elizabeth Ruckdeschel, MD, PhD Assistant Professor, Dept of Pathology, SUNY Upstate Medical University, Syracuse, NY Jagmohan Sidhu, MD Director & Chairman of Pathology, UHS Hospitals, Johnson City/Binghamton, NY

Agenda continued Ramona Vesna Untanu, MD Hematopathology Fellow, SUNY Upstate Medical University, Syracuse, NY Gang Yue, MD, PhD Hematopathologist, UHS Hospitals, Johnson City/Binghamton, NY

Agenda for FRIday EVENING (May 20, 2016) Non-CME Activity

Keynote Speaker

Location: Comstack A Conference Room

Ahmet Dogan, MD, PhD Chief of Hematopathology Memorial Sloan Kettering Cancer Center, New York, NY

6:00pm Reception 7:00pm Genomic Profiling of Non-Hodgkin Lymphoma: Examples and Comparison to Traditional Testing Technologies Bashar Dabbas, MD, Medical Director, Genoptix Medical Laboratory, Division of Novartis 8:00pm Dinner

Faculty John Astle, MD, PhD Hematopathology Fellow, Yale University, New Haven CT Katalin Banki, MD Associate Professor of Pathology, SUNY Upstate Medical University, Syracuse, NY Abaigail Bird Pre-Medical Student, Utica Collage, Utica, NY W. Richard Burack, MD, PhD Director of Hematopathology, University of Rochester, Rochester, NY George Deeb, MD Director of Flow Cytometry, Emory University Hospital, Atlanta, GA Andrew Evans, MD, PhD Assistant Professor, Dept. of Pathology, University of Rochester, Rochester, NY Robert Hutchison, MD Director of Clinical Pathology, SUNY Upstate Medical University Syracuse, NY Serazul Khan, MD Hematologist & Oncologist, UHS Oncology, Johnson City, NY

Shridevi Karikehalli, MD Director of Hematopathology, Centrex Clinical Laboratories, Utica, NY Hani Katerji, MD Pathology Resident, University of Rochester, Rochester, NY Mihai Merzianu, MD Associate Professor, Dept of Pathology Roswell Park Cancer Institute, Buffalo, NY Tipu Nazeer, MD Director of Surgical Pathology & Hematopathology, Albany Medical Center, Albany, NY Vishala Neppalli, MD Assistant Professor, Dept of Pathology, Roswell Park Cancer Institute, Buffalo, NY Narendra Panesar, MD Pathologist, UHS Hospitals Johnson City/Binghamton, NY Nisha Patel, MD Hematopathology Fellow, University of Rochester, Rochester NY Danielle Robinson, DO Medical Student, UHS Hospitals Johnson City/Binghamton, NY

Agenda for SYMPOSIUM (May 21, 2016) 7:30am Registration Cheryl Connoly, Lindsey Bird and Tracie Bird 8:00am Welcome & Introductions James Hayes, MD 8:10am Pre-test 8:20am Keynote Lecture: Beyond Morphology: Phenotypic and Genetic Predictors of Clinical Behavior in B-Cell Lymphoma Ahmet Dogan, MD, PhD 9:20am Case Study: Indolent B-Cell Lymphoma with Aggressive Features W. Richard Burack, MD, PhD 9:32am Case Study: Large B-Cell Lymphoma with Unexpected Indolent Behavior Andrew Evans, MD, PhD 9:44am Case Study: Gray Zone Lymphoma with Features in Between Classic Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Mihai Merzianu,MD 9:56am Case Study: De Novo Large B-Cell Lymphoma with Morphologic Features Suggesting More Aggressive Behavior Vishala Neppalli, MD 10:08am Coffee Break 10:23am Case Study: Diffuse Large B-Cell Lymphoma with Triple Hit Tipu Nazeer, MD 10:35am Case Study: Intravascular Large B-Cell Lymphoma with a Complex Karyotype Katalin Banki, MD

10:47am DOUGLAS NELSON LECTURE: Epigenetic Predictors of Clinical Behavior in B-Cell Lymphoma Robert Hutchison, MD 11:30am SPECIAL LECTURE: Flow Cytometric Predictors of Clinical Behavior in B-Cell Lymphoma George Deeb, MD 12:10pm De Novo Large B-Cell Lymphoma with Molecular Features Suggesting More Aggressive Behavior Elizabeth Ruckdeschel, MD, PhD 12:22pm Lunch Break 1:20pm Case Study: Burkitt Lymphoma with Atypical Features Nisha Patel, MD 1:32pm Case Study: Indolent B-Cell Lymphoma with Aggressive Features Hani Katerji, MD 1:44pm Case Study: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Accelerated Type Gang Yue, MD, PhD 1:56am NEXT-GENERATION PATHOLOGY LECTURE: Improving Quality and Structure of Big Data in Pathology John Astle, MD, PhD 2:30pm Case Study: Intrafollicularly Transformed Follicular Lymphoma Showing Blastoid, Not Large Cell, Transformation Narendra Panesar, MD 2:42pm Case Study: Diffuse Large B-Cell Lymphoma Co-Expressing MYC & BCL2 and Showing MYC & BCL6 Translocations Ramona Vesna Untanu, MD 2:54pm Coffee Break 3:10pm Case Study: CD5-Positive Diffuse Large B-Cell Lymphoma Showing Extensive Sinusoido-Angiotropism Danielle Robinson, DO 3:22pm Case Study: CD5-Positive Intravascular Large B-Cell Lymphoma Abaigail Bird 3:32pm Case Study: CD15-Positive Intravascular Large B-Cell Lymphoma Shridevi Karikehalli, MD 3:44pm Case Study: ALK-Positive Diffuse Large B-Cell Lymphoma Showing Angiotropism Jagmohan Sidhu, MD 3:56pm HEMATO-ONCOLOGY LECTURE: Current and Emerging Therapies for B-Cell Lymphomas with Expected and Unexpected Clinical Behavior Serazul Khan, MD 4:46pm Post-Test / Take-Home Messages / Adjournment Jagmohan Sidhu, MD and Serazul Khan, MD **For a CME Certificate all completed evaluations and pre/post tests must be turned in at the registration desk.

Ronald Harris, DO Jagmohan Sidhu, MD James Hayes, MD Tracie Bird Cheryl Connolly Program objectives Recognize morphologic and immunophenotypic features that predict unexpected behavior of B-cell lymphomas. Recognize genetic and epigenetic features that predict unexpected behavior of B-cell lymphomas. Describe current and emerging therapies for B-cell lymphomas based on their predicted clinical behavior. acknowledgements UHS/UHS Medical Group and Broome Oncology are grateful to the pharmaceutical and laboratory technology industries for their generous unrestricted educational support of this continuing education program. A full list of contributors will be included in the meeting syllabus. mission UHS is a comprehensive regional health system whose mission is to improve the health of those we serve through our commitment to excellence in all that we do. vision UHS, the region’s leading integrated healthcare system, will demonstrate exceptional value in the delivery of coordinated, patient-centered care.

Program Coordinators

Hematology/Hematopathology Symposium INTENDED AUDIENCE The faculty will speak to the educational needs of the hematologists, oncologists, pathologists, hematopathologists, pathology and internal medicine residents and fellows, medical students, students in biology-related studies, hematology and flow cytometry technologists, physician assistants, nurse practitioners, and nurses.

Faculty continued Elizabeth Ruckdeschel, MD, PhD Assistant Professor, Dept of Pathology, SUNY Upstate Medical University, Syracuse, NY Jagmohan Sidhu, MD Director & Chairman of Pathology, UHS Hospitals, Johnson City/Binghamton, NY

Agenda continued Ramona Vesna Untanu, MD Hematopathology Fellow, SUNY Upstate Medical University, Syracuse, NY Gang Yue, MD, PhD Hematopathologist, UHS Hospitals, Johnson City/Binghamton, NY

Agenda for FRIday EVENING (May 20, 2016) Non-CME Activity

Keynote Speaker

Location: Comstack A Conference Room

Ahmet Dogan, MD, PhD Chief of Hematopathology Memorial Sloan Kettering Cancer Center, New York, NY

6:00pm Reception 7:00pm Genomic Profiling of Non-Hodgkin Lymphoma: Examples and Comparison to Traditional Testing Technologies Bashar Dabbas, MD, Medical Director, Genoptix Medical Laboratory, Division of Novartis 8:00pm Dinner

Faculty John Astle, MD, PhD Hematopathology Fellow, Yale University, New Haven CT Katalin Banki, MD Associate Professor of Pathology, SUNY Upstate Medical University, Syracuse, NY Abaigail Bird Pre-Medical Student, Utica Collage, Utica, NY W. Richard Burack, MD, PhD Director of Hematopathology, University of Rochester, Rochester, NY George Deeb, MD Director of Flow Cytometry, Emory University Hospital, Atlanta, GA Andrew Evans, MD, PhD Assistant Professor, Dept. of Pathology, University of Rochester, Rochester, NY Robert Hutchison, MD Director of Clinical Pathology, SUNY Upstate Medical University Syracuse, NY Serazul Khan, MD Hematologist & Oncologist, UHS Oncology, Johnson City, NY

Shridevi Karikehalli, MD Director of Hematopathology, Centrex Clinical Laboratories, Utica, NY Hani Katerji, MD Pathology Resident, University of Rochester, Rochester, NY Mihai Merzianu, MD Associate Professor, Dept of Pathology Roswell Park Cancer Institute, Buffalo, NY Tipu Nazeer, MD Director of Surgical Pathology & Hematopathology, Albany Medical Center, Albany, NY Vishala Neppalli, MD Assistant Professor, Dept of Pathology, Roswell Park Cancer Institute, Buffalo, NY Narendra Panesar, MD Pathologist, UHS Hospitals Johnson City/Binghamton, NY Nisha Patel, MD Hematopathology Fellow, University of Rochester, Rochester NY Danielle Robinson, DO Medical Student, UHS Hospitals Johnson City/Binghamton, NY

Agenda for SYMPOSIUM (May 21, 2016) 7:30am Registration Cheryl Connoly, Lindsey Bird and Tracie Bird 8:00am Welcome & Introductions James Hayes, MD 8:10am Pre-test 8:20am Keynote Lecture: Beyond Morphology: Phenotypic and Genetic Predictors of Clinical Behavior in B-Cell Lymphoma Ahmet Dogan, MD, PhD 9:20am Case Study: Indolent B-Cell Lymphoma with Aggressive Features W. Richard Burack, MD, PhD 9:32am Case Study: Large B-Cell Lymphoma with Unexpected Indolent Behavior Andrew Evans, MD, PhD 9:44am Case Study: Gray Zone Lymphoma with Features in Between Classic Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma Mihai Merzianu,MD 9:56am Case Study: De Novo Large B-Cell Lymphoma with Morphologic Features Suggesting More Aggressive Behavior Vishala Neppalli, MD 10:08am Coffee Break 10:23am Case Study: Diffuse Large B-Cell Lymphoma with Triple Hit Tipu Nazeer, MD 10:35am Case Study: Intravascular Large B-Cell Lymphoma with a Complex Karyotype Katalin Banki, MD

10:47am DOUGLAS NELSON LECTURE: Epigenetic Predictors of Clinical Behavior in B-Cell Lymphoma Robert Hutchison, MD 11:30am SPECIAL LECTURE: Flow Cytometric Predictors of Clinical Behavior in B-Cell Lymphoma George Deeb, MD 12:10pm De Novo Large B-Cell Lymphoma with Molecular Features Suggesting More Aggressive Behavior Elizabeth Ruckdeschel, MD, PhD 12:22pm Lunch Break 1:20pm Case Study: Burkitt Lymphoma with Atypical Features Nisha Patel, MD 1:32pm Case Study: Indolent B-Cell Lymphoma with Aggressive Features Hani Katerji, MD 1:44pm Case Study: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Accelerated Type Gang Yue, MD, PhD 1:56am NEXT-GENERATION PATHOLOGY LECTURE: Improving Quality and Structure of Big Data in Pathology John Astle, MD, PhD 2:30pm Case Study: Intrafollicularly Transformed Follicular Lymphoma Showing Blastoid, Not Large Cell, Transformation Narendra Panesar, MD 2:42pm Case Study: Diffuse Large B-Cell Lymphoma Co-Expressing MYC & BCL2 and Showing MYC & BCL6 Translocations Ramona Vesna Untanu, MD 2:54pm Coffee Break 3:10pm Case Study: CD5-Positive Diffuse Large B-Cell Lymphoma Showing Extensive Sinusoido-Angiotropism Danielle Robinson, DO 3:22pm Case Study: CD5-Positive Intravascular Large B-Cell Lymphoma Abaigail Bird 3:32pm Case Study: CD15-Positive Intravascular Large B-Cell Lymphoma Shridevi Karikehalli, MD 3:44pm Case Study: ALK-Positive Diffuse Large B-Cell Lymphoma Showing Angiotropism Jagmohan Sidhu, MD 3:56pm HEMATO-ONCOLOGY LECTURE: Current and Emerging Therapies for B-Cell Lymphomas with Expected and Unexpected Clinical Behavior Serazul Khan, MD 4:46pm Post-Test / Take-Home Messages / Adjournment Jagmohan Sidhu, MD and Serazul Khan, MD **For a CME Certificate all completed evaluations and pre/post tests must be turned in at the registration desk.

Ronald Harris, DO Jagmohan Sidhu, MD James Hayes, MD Tracie Bird Cheryl Connolly Program objectives Recognize morphologic and immunophenotypic features that predict unexpected behavior of B-cell lymphomas. Recognize genetic and epigenetic features that predict unexpected behavior of B-cell lymphomas. Describe current and emerging therapies for B-cell lymphomas based on their predicted clinical behavior. acknowledgements UHS/UHS Medical Group and Broome Oncology are grateful to the pharmaceutical and laboratory technology industries for their generous unrestricted educational support of this continuing education program. A full list of contributors will be included in the meeting syllabus. mission UHS is a comprehensive regional health system whose mission is to improve the health of those we serve through our commitment to excellence in all that we do. vision UHS, the region’s leading integrated healthcare system, will demonstrate exceptional value in the delivery of coordinated, patient-centered care.

REGISTRATION (Please Print): n Practicing Physicians n Honorary Physicians n UHS Nurses/Staff n Non-UHS Nurses/Staff n Residents/Students

$80 $35 $30 $40 $0

CREDIT DESIGNATION: SUNY Upstate Medical University designates this live activity for a maximum of 7.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

UHS in conjunction with Broome Oncology present

11th Annual Hematology/ Hematopathology Symposium

DISCLOSURE POLICY: To ensure balance, independence, objectivity, and scientific rigor in all certified CME activity SUNY Upstate Medical University requires that all planners, faculty and individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest that might be perceived as a real or apparent conflict of interest. Detailed disclosures will be made in writing prior to speaker presentations.

ADDRESS STATE

ZIP

E-MAIL DAY PHONE

n Will also attend May 20, Educational Dinner Pgm

PAYMENT OPTIONS: n Checks payable to: UHS CPE Department n Charge to my credit card: n Visa n Master Card n AmEx n Discover Account# Exp. Date: Signature: n UHS employees may pay: I have authorized the registrant to attend this Teaching Day as a UHS employee. I authorize UHS to bill my: Cost Center _________________ for $___________ Mgr. Signature ______________________ Mgr. Phone _____________________ Mail/Fax Registration Form To:

UHS Wilson Medical Center Department of Pathology, Attn: Tracie Bird 33–57 Harrison Street, Johnson City, NY 13790 Fax: (607) 763-5252 Enrollment is limited. Registration and payment is due by May 6, 2016. After that date, add $5 for late processing fee. Registrations may be verified by calling (607) 763-6285.

Saturday, May 21, 2016 8:00am – 5:00pm

AMERICANS WITH DISABILITIES ACT (ADA): In accordance with the Americans with Disabilities Act, SUNY Upstate Medical University seeks to make this conference accessible to all. If you have a disability which might require special accommodations, please contact Tracie Bird (607) 763-6285.

Beyond Morphology: Phenotypic & Genetic Predictors of Clinical Behavior in B-Cell Lymphoma

REFUNDS and VERIFICATION: A full refund of your registration fee is available with written cancellation on or before May 6, 2016. After May 6th there is a $10.00 processing fee. HOTEL Reservations: A block of rooms will be held at a special conference rate of $149.00 for a single or double room. Note: This rate is only good until April 28, 2016. A room can be reserved by calling Sheraton Syracuse University at (800) 395-2105. Be sure to reference the “H/H 2016 Symposium” to get the discounted rate. There is a $13.00 charge per day for hotel parking.

A Symposium

Keynote Speaker Ahmet Dogan, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, NY

DIRECTIONS to SHERATON SYRACUSE UNIVERSITY HOTEL: From Syracuse Hancock International Airport and points North: Take Interstate 81 South to Exit 18 (Adams Street). Bear left and go to the 2nd light. Turn left on East Adams. At the 4th light turn right on University Avenue. The hotel is 2 blocks on the left. From Albany, NY and points East: Take Interstate 90 to Exit 34A. Take 481 South to 690 West to the Teall Avenue Exit. Turn left onto Teall and go to the 2nd light. Turn right onto Erie Boulevard East and then left onto University Avenue. Go for 7 blocks and the hotel will be on the left. From Buffalo, NY and points West: Take Interstate 90 East to Exit 39. Take 690 East to 81 South and take Exit 18 (Adams Street). Follow the signs to Adams Street and then turn left onto Adams. At the 4th light, turn right onto University Avenue. The hotel will be on the left. From New York City: Take Route 17 to Binghamton. Take I-81 North to Syracuse and then take Exit 18 (Harrison/Adams Street). Turn right on East Adams Street. Go to the 4th traffic light and turn right onto University Avenue. Hotel is two blocks on the left. From points South: Take 81 North to Exit 18 (Harrison/Adams Street). Turn right onto East Adams Street. Go to the 4th traffic light and turn right onto University Avenue. Hotel is two blocks down on the left. UHS/LS/06/03/16/7C

Address Service requested

ORGANIZATION

Tracie Bird, Dept. of Pathology UHS Wilson Medical Center 33–57 Harrison Street Johnson City, New York 13790

NAME/TITLE

CITY

ACCREDITATION: This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of SUNY Upstate Medical University and United Health Services. SUNY Upstate Medical University is accredited by the ACCME to provide continuing medical education for physicians.

Non-Profit Organization U.S. Postage PAID Binghamton, NY Permit No. 175

Hematology/Hematopathology Symposium

Friday, May 20, 2016 6:00pm – 10:00pm

Note: Register for the symposium online at uhs.net/HHSymposium

Educational Dinner Program Sponsored by Genoptix (Non-CME Activity)

Sheraton Syracuse University Hotel & Conference Center Syracuse, NY

Hematology/Hematopathology Symposium REGISTRATION (Please Print): n Practicing Physicians $80 n Honorary Physicians $35 n UHS Nurses/Staff $30 n Non-UHS Nurses/Staff $40 n Residents/Students $0 NAME/TITLE ORGANIZATION ADDRESS CITY

STATE ZIP

E-MAIL

Program Coordinators Ronald Harris, DO Jagmohan Sidhu, MD James Hayes, MD Tracie Bird Cheryl Connolly Program objectives Recognize morphologic and immunophenotypic features that predict unexpected behavior of B-cell lymphomas. Recognize genetic and epigenetic features that predict unexpected behavior of B-cell lymphomas. Describe current and emerging therapies for B-cell lymphomas based on their predicted clinical behavior.

DAY PHONE

n Will also attend May 20, Educational Dinner Pgm

PAYMENT OPTIONS: n Checks payable to: UHS CPE Department n Charge to my credit card: n Visa n Master Card n AmEx n Discover Account# Exp. Date: Signature: n UHS employees may pay: I have authorized the registrant to attend this Teaching Day as a UHS employee. I authorize UHS to bill my: Cost Center _________________ for $___________ Mgr. Signature ______________________ Mgr. Phone _____________________ Mail/Fax Registration Form To:

UHS Wilson Medical Center Department of Pathology, Attn: Tracie Bird 33–57 Harrison Street, Johnson City, NY 13790 Fax: (607) 763-5252 Enrollment is limited. Registration and payment is due by May 6, 2016. After that date, add $5 for late processing fee. Registrations may be verified by calling (607) 763-6285.

acknowledgements UHS/UHS Medical Group and Broome Oncology are grateful to the pharmaceutical and laboratory technology industries for their generous unrestricted educational support of this continuing education program. A full list of contributors will be included in the meeting syllabus. mission UHS is a comprehensive regional health system whose mission is to improve the health of those we serve through our commitment to excellence in all that we do. vision UHS, the region’s leading integrated healthcare system, will demonstrate exceptional value in the delivery of coordinated, patient-centered care.