Global Aesthetic Market XIV
M.I.I
June 2016
Disclaimer
Information in this study has been obtained by Medical Insight, Inc., from sources believed to be reliable. While Medical Insight believes the data provided herein to be accurate, no expressed or implied guarantees regarding accuracy or adequacy are made. Product and corporate data can change very quickly and without notice and Medical Insight continually updates its research products. Because of this, certain figures in Medical Insight reports may differ from corresponding figures in earlier reports, even if those reports were issued relatively recently. Furthermore, current economic conditions are contributing to a highly volatile market, in which actual results often diverge significantly from estimates developed by manufacturers, analysts and others, resulting in a revision of projections. Therefore, while Medical Insight will provide an explanation of figures in any of its reports, only the most recent reports contain Medical Insight’s latest estimates. This study is not intended as a substitute for proper due diligence. Although an attempt has been made to provide thorough coverage of the subject matter of this report, no guarantees regarding completeness or thoroughness are made. Medical Insight is not responsible for any errors, omissions, or results obtained from use of information provided herein. Any use which a reader makes of this report or any reliance on or decisions to be made based on it are the sole responsibility of such reader. Medical Insight accepts no responsibility for damages, if any, suffered by any reader as a result of decisions or actions taken based on this study. Medical Insight, Inc. reserves all rights to this copyrighted document. This study is protected by U.S. Copyright Law; Copyright 2016 Medical Insight, Inc. Unauthorized reproduction is strictly forbidden by law. This report may not be reproduced in part or in whole without written consent of a duly authorized officer of Medical Insight. Multiple copies of this report can be obtained at a nominal cost by contacting the publisher. Medical Insight, Inc. 130 Vantis, Suite 240 Aliso Viejo, CA 92656 USA +1 (949) 830-5409 telephone +1 (949) 830-8944 facsimile Email:
[email protected]
www.miinews.com
Medical Insight, Inc.
2
Global Aesthetic Market XIV
M.I.I
June 2016
Professional Biography
Michael Moretti President Medical Insight, Inc. Michael Moretti has served as a medical industry analyst and strategic advisor for more than 20 years. As an industry consultant, Mr. Moretti specializes in strategic business development projects and high-growth, emerging market segments. He provides custom reports and confidential market studies for a variety of clients, including global medical and pharmaceutical companies. In 1993, Mr. Moretti founded Medical Insight, Inc., the leader in focused aesthetic market research offering comprehensive data on procedure volume and growth, revenue forecasts and new product introductions. Under Mr. Moretti’s leadership, Medical Insight publishes global market studies and forecasts for major industry sectors such as facial injectables, cosmeceuticals, body shaping procedures, skin rejuvenation technologies and home-use aesthetic products. Medical Insight also sponsors executive business forums to address scientific developments and market trends for the investment community. Mr. Moretti is the founder of Aesthetic TV, the first and only one-stop online resource for current, reliable information about cosmetic and anti-aging treatments. Aesthetic TV offers expert advice for consumers via interviews with the top physicians in the field, and unprecedented access to the latest beauty-enhancing procedures and products created specifically to help people look and feel their absolute best. Mr. Moretti is also founder and publisher of THE Aesthetic Guide® – a digital and print publication from Medical Insight featuring in-depth reports on new products, procedures and trends, reaching over 75,000 physicians, industry executives and investment analyst subscribers globally. Special editions of THE Aesthetic Guide address the European and Asian markets. In 2007, Mr. Moretti debuted THE Aesthetic Show™, the first multidisciplinary annual business to business trade show that brings thousands of the highest profile physicians and medical professionals together in Las Vegas to learn about the newest aesthetic procedures, products and technologies in a dynamic, interactive, educational format. For more information please visit: www.miinews.com. Contact Information: Michael Moretti Medical Insight, Inc. 130 Vantis, Suite 240 Aliso Viejo, CA 92656 USA +1 (949) 830-5409 telephone +1 (949) 830-8944 facsimile Email:
[email protected] Or visit the Medical Insight website at: www.miinews.com
www.miinews.com
Medical Insight, Inc.
3
Global Aesthetic Market XIV
M.I.I
June 2016
Table of Contents
Disclaimer
2
Professional Biography
3
Table of Contents
4
Table of Exhibits
17
1.0 2.0
Executive Summary Background 2.1
3.0
28 30 30
The Aging Process 2.1.1
Free Radical Theory
30
2.1.2
Inflammation
31
2.1.3
Immune System Response
31
Energy-Based Devices and Treatments 3.1
3.2
3.3
33
Overview of Energy Types and Treatments 3.1.1
Laser Devices
36
3.1.2
Intense Pulsed Light
37
3.1.3
Light-Emitting Diodes
37
3.1.4
Light Heat Energy
37
3.1.5
Energy-Based Epilation
37
3.1.6
Skin Rejuvenation
38
3.1.7
Tattoo & Pigmented Lesion Removal
40
3.1.8
Acne Reduction
42
3.1.9
Vascular Lesions
42 43
Competitive Advantage 3.2.1
Energy-Based Epilation
43
3.2.2
Skin Rejuvenation
46
3.2.3
Tattoo and Pigmented Lesion Removal
47
3.2.4
Acne Reduction
47
3.2.5
Treatment of Vascular Lesions
48 49
Device Descriptions and Results 3.3.1
50
Energy-Based Epilation 3.3.1.1
www.miinews.com
33
53
Alexandrite Lasers
Medical Insight, Inc.
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Global Aesthetic Market XIV
3.3.2
3.4
www.miinews.com
June 2016
3.3.1.2
Diode Lasers
54
3.3.1.3
Nd:YAG Lasers
54
3.3.1.4
Pulsed Light Devices
55
3.3.1.5
Electro-Optical Synergy
55 55
Skin Rejuvenation 3.3.2.1
Ablative Skin Rejuvenation
59
3.3.2.2
Non-Ablative Skin Rejuvenation
59
3.3.2.3
Fractional Skin Rejuvenation
59
3.3.3
Tattoo and Pigmented Lesion Removal
63
3.3.4
Acne Reduction
64
3.3.4.1
Bactericidal Approach
66
3.3.4.2
Cessation of Oil Porduction Appraoch
67
3.3.4.3
Photopneumatic
67
3.3.5
Vaginal Rejuvenation
68
3.3.6
Vascular Lesions
69 72
Manufacturer Profiles 3.4.1
Alma Lasers
72
3.4.2
AMT Engineering
75
3.4.3
BTL Aesthetics
76
3.4.4
Cutera
77
3.4.5
Cynosure
78
3.4.6
EL.EN. Group
81
3.4.7
Ellipse
83
3.4.8
EndyMed
83
3.4.9
Energist
84
3.4.10
Focus Medical
85
3.4.11
Fotona
85
3.4.12
General Project
87
3.4.13
Hironic
87
3.4.14
ILOODA
88
3.4.15
InMode
88
3.4.16
Jeisys
89
3.4.17
LASERING
89
3.4.18
Lumenis
90
3.4.19
Lutronic
92
3.4.20
Medicol USA
93
Medical Insight, Inc.
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Global Aesthetic Market XIV
3.5
4.0
June 2016
3.4.21
Meditime
93
3.4.22
MedixSysteme
94
3.4.23
Pantec Biosolutions
94
3.4.24
Perfaction
94
3.4.25
Pollogen
95
3.4.26
Protocadmus
96
3.4.27
Radiancy / PhotoMedex
96
3.4.28
Sciton
97
3.4.29
SharpLight
99
3.4.30
Solta / Valeant
100
3.4.31
SupraMedical
101
3.4.32
Syneron Candela
102
3.4.33
Thermi
104
3.4.34
Viora
105
3.4.35
Viveve Medical
106
Equipment Sales Estimates 2015 – 2020
107
3.5.1
Platforms
108
3.5.2
Disposables
122
3.6
Treatment Volume Estimates 2015 – 2020
130
3.7
Competitive Analysis and Market Share
143
Body Shaping & Skin Tightening
145
4.1
Overview of Condition and Treatment
145
4.2
Competitive Advantage
148
4.3
Device Descriptions and Results
149
4.4
Manufacturer Profiles
153
www.miinews.com
4.4.1
Alma Lasers
153
4.4.2
Andrew Technologies
154
4.4.3
BTL Industries
154
4.4.4
CAREstream America
155
4.4.5
Chromogenex
156
4.4.6
Classys
157
4.4.7
Cutera
157
4.4.8
Cynosure
158
4.4.9
EL.EN Group (Asclepion, DEKA, Quanta System)
160
Medical Insight, Inc.
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4.5
www.miinews.com
June 2016
4.4.10
EndyMed
161
4.4.11
Energist
163
4.4.12
Erchonia
163
4.4.13
EunSung Global Corp.
164
4.4.14
Fotona
166
4.4.15
General Project
166
4.4.16
Grupo Body Esthetic Laboratories
167
4.4.17
Hironic
168
4.4.18
InMode
168
4.4.19
Jeisys
169
4.4.20
LoveLite Ltd.
170
4.4.21
Lutronic
170
4.4.22
Meditime
171
4.4.23
MedixSysteme
171
4.4.24
Merz (Ulthera)
173
4.4.25
Perigee Medical
174
4.4.26
Pollogen
174
4.4.27
Protocadmus Technologies
176
4.4.28
Sciton
176
4.4.29
SharpLight Technologies
177
4.4.30
Shenzhen GSD Tech
177
4.4.31
Silhouet-Tone
178
4.4.32
STORZ Medical
178
4.4.33
Strawberry Laser Lipo
179
4.4.34
Syneron
178
4.4.35
ThermaMedic
181
4.4.36
Thermi
182
4.4.37
Valeant (Solta Medical)
183
4.4.38
Venus Concept
186
4.4.39
Viora
186
4.4.40
ZELTIQ Aesthetics
187
4.4.41
Zimmer MedizinSysteme
190 191
Equipment Sales Estimates 2015 to 2020 4.5.1
Platforms
191
4.5.2
Disposable
203
Medical Insight, Inc.
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Global Aesthetic Market XIV
5.0
4.6
Treatment Volume Estimates 2015 to 2020
214
4.7
Competitive Analysis and Market Share
222
Neurotoxins
224
5.1
Overview of Condition and Treatment
224
5.2
Competitive Advantage
226
5.3
Product Descriptions and Results
227
5.4
6.0
June 2016
5.3.1
BTX-A
228
5.3.2
BTX-B
229 230
Manufacturer Profiles 5.4.1
Allergan
230
5.4.2
ALPHAEON Corp.
234
5.4.3
Daewoong Pharma
234
5.4.4
Ipsen
235
5.4.5
Galderma
235
5.4.6
HuGel
237
5.4.7
Lanzhou Institute
237
5.4.8
MedyTox
238
5.4.9
Merz
239
5.4.10
Revance Therapeutics
240
5.5
Product Sales Estimates 2015 to 2020
242
5.6
Treatment Volume Estimates 2015 to 2020
253
5.7
Competitive Analysis and Market Share
259
Dermal Fillers
261
6.1
Overview of Conditions and Treatments
261
6.2
Competitive Advantage
263
6.3
Product Descriptions and Results
265
6.4
Manufacturer Profiles
268
www.miinews.com
6.4.1
Adoderm
268
6.4.2
Aesthetic Factors
269
6.4.3
Allergan
269
6.4.4
ALPHAEON Corp.
270
6.4.5
Biologica Tech
270
6.4.6
Bloomage
270
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Global Aesthetic Market XIV
7.0
June 2016
6.4.7
CM Aesthetic
271
6.4.8
Contura / Specialty European Pharma
271
6.4.9
Cosmoscience
272
6.4.10
Croma-Pharma
273
6.4.11
Fibrocell
273
6.4.12
Laboratoires FILORGA
274
6.4.13
Galderma
274
6.4.14
Hangzhou Gallop Biological Products
276
6.4.15
Hangzhou Sinclean Medical Products
276
6.4.16
Harvest Technologies Corp.
277
6.4.17
IBSA Farmaceutici Italia
277
6.4.18
Kaylight
278
6.4.19
LG Life Sciences
279
6.4.20
Merz Aesthetics
279
6.4.21
NovoNexus
280
6.4.22
O’Meiye Group
280
6.4.23
Procytech / The Cell Bio-Tech (China)
280
6.4.24
Prollenium Medical Technologies
281
6.4.25
RegenLab
281
6.4.26
Regenyal
281
6.4.27
Revitacare
282
6.4.28
SBS-Med
283
6.4.29
Sinclair Pharma
283
6.4.30
Suiselle
285
6.4.31
Suneva Medical
285
6.4.32
Teoxane
287
6.4.33
Vivacy
288
6.4.34
Zimmer MedizinSysteme
289
6.5
Product Sales Estimates 2015 to 2020
290
6.6
Treatment Volume Estimates 2015 to 2020
301
6.7
Competitive Analysis and Market Share
307
Liposuction 7.1
www.miinews.com
309 309
Overview of Conditions and Treatments
Medical Insight, Inc.
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Global Aesthetic Market XIV
8.0
June 2016
7.2
Competitive Advantage
310
7.3
Product Descriptions and Results
311
7.4
Manufacturer Profiles
312
7.4.1
Mentor
312
7.4.2
MicroAire
312
7.4.3
Valeant
312
7.4.4
Wells Johnson
313
7.5
Product Sales Estimates 2015 to 2020
314
7.6
Prcedure Volume
325
7.7
Competitive Analysis and Market Share
329
Breast Implants
331
8.1
Overview of Condition and Treatment
331
8.2
Competitive Advantage
332
8.3
Product Descriptions and Results
333
8.4
8.3.1
Saline Implants
334
8.3.2
Silicone Implants
335 337
Manufacturer Profiles 8.4.1
Allergan
337
8.4.2
GC Aesthetics
338
8.4.3
Mentor
339
8.4.4
PIP
340
8.4.5
Sientra
341
8.4.6
Silimed
342
8.4.7
Valeant
343
8.5
Product Sales Estimates 2015 to 2020
345
8.6
Procedure Volume
356
8.7
Competitive Analysis and Market Share
360
9.0 Physician-Dispensed Topicals, Peels and Eyelash Products
362
9.1
Overview of Conditions and Treatments
362
9.2
Competitive Advantage
367
9.3
Product Descriptions and Results
369
9.3.1
www.miinews.com
370
Ingredients 9.3.1.1
Vitamin A and Retinoids
371
9.3.1.2
Vitamin C
371
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Global Aesthetic Market XIV
9.4
www.miinews.com
June 2016
9.3.1.3
Vitamin E
372
9.3.1.4
Alpha Lipoic Acid
372
9.3.1.5
Coenzyme Q10
373
9.3.1.6
Aminophylline
374
9.3.1.7
Argirelene
375
9.3.1.8
Beta Hydroxy Acids
375
9.3.1.9
Ceramides
375
9.3.1.10
Coconut Oil
376
9.3.1.11
Coenzyme Q10
376
9.3.1.12
Creatine
377
9.3.1.13
Cytokinin & Zeatin
377
9.1.3.14
DMAE
377
9.1.3.15
Epigallocatechin Gallate
378
9.1.3.16
Growth Factors
378
9.1.3.17
Hyaluronic Acid
379
9.1.3.18
Idebenone
379
9.1.3.19
Melanozyme
380
9.1.3.20
Peptides
380
9.1.3.21
Silica Silylate
381
9.3.1.22
Latest Developments in Formulations
381
9.3.2
Chemical Peels
387
9.3.3
Eyelash Products
391
9.3.4
Scar Products
393
9.3.5
Skin Lightening / Brightening
394
9.3.6
Sunscreens
395 398
Manufacturer Profiles 9.4.1
A Plus Medical
398
9.4.2
Alastin Skincare
398
9.4.3
Allergan
399
9.4.4
ALPHAEON Corp.
401
9.4.5
Athena Cosmetics
402
9.4.6
Biodermis
403
9.4.7
BiON Research
403
Medical Insight, Inc.
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Global Aesthetic Market XIV
www.miinews.com
June 2016
9.4.8
Biopelle
403
9.4.9
Cellese
404
9.4.10
Celuvia
404
9.4.11
Clinicians Complex
404
9.4.12
Cosmederm Bioscience
405
9.4.13
Cosmedical Technologies
405
9.4.14
Cutagenesis
405
9.4.15
Derma e
405
9.4.16
Dermaesthetics
406
9.4.17
Dermamedics
406
9.4.18
Dermaquest
406
9.4.19
DermAware
406
9.4.20
Derme&Co.
407
9.4.21
DermWORX
407
9.4.22
Enaltus
407
9.4.23
Enhance Skin Products
408
9.4.24
Environ
408
9.4.25
Envy Medical
408
9.4.26
EltaMD
409
9.4.27
Epikinetics
410
9.4.28
Episciences
410
9.4.29
Eraclea
410
9.4.30
exCel Cosmeceuticals
411
9.4.31
Fallene
411
9.4.32
Laboratoires Filorga
412
9.4.33
Galderma
412
9.4.34
glo Professional
413
9.4.35
GMC Medical
413
9.4.36
Hale Cosmeceuticals
413
9.4.37
Hand MD
413
9.4.38
HydroPeptide
414
9.4.39
Illuminare Skincare
414
9.4.40
INNOCUTIS
414
Medical Insight, Inc.
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Global Aesthetic Market XIV
www.miinews.com
June 2016
9.4.41
Innovative Skincare
415
9.4.42
Intrafusions
415
9.4.43
Jan Marini
415
9.4.44
LA Canada Ventures
416
9.4.45
La-Roche Posay
417
9.4.46
LEIO Corporation
418
9.4.47
LifeLine Skincare
418
9.4.48
LIFTLAB
418
9.4.49
Lira Cosmeceuticals
419
9.4.50
MD Formulations
419
9.4.51
Medicalia
420
9.4.52
Mesoestetic Pharma Group
420
9.4.53
Murad
420
9.4.54
Mybody
421
9.4.55
mySkin
422
9.4.56
Neocutis (Merz)
423
9.4.57
NeoStrata
423
9.4.58
NewMedical Technology
423
9.4.59
Niadyne Pharma
424
9.4.60
Novo Solutions
424
9.4.61
NuGene International
425
9.4.62
NuvesseMD
425
9.4.63
Obagi Medical (Valeant)
425
9.4.64
Osmosis Pur Medical Skincare
426
9.4.65
Oxygenetix Institute
427
9.4.66
PCA SKIN
427
9.4.67
Pevonia
427
9.4.68
PhotoMedex
427
9.4.69
PhytoCeuticals
428
9.4.70
Pierre Fabre
429
9.4.71
Revision Skincare
429
9.4.72
SAIAN
429
9.4.73
Scar Heal
430
Medical Insight, Inc.
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Global Aesthetic Market XIV
10.0
June 2016
9.4.74
Scarguard Labs
430
9.4.75
Sente
430
9.4.76
Sesderma
431
9.4.77
SkinCeuticals (L’Oreal)
431
9.4.78
Skinprint
432
9.4.79
Suneva Medical
432
9.4.80
Syneron
432
9.4.81
Teoxane
433
9.4.82
Therapon
434
9.4.83
Topokine Therapeutics (Allergan)
434
9.4.84
Turo Skin
435
9.4.85
US CosmeceuTechs
435
9.4.86
Venus Skin
435
9.4.87
Young Pharmaceuticals
435
9.4.88
ZO Skin Health
436
9.5
Product Sales Estimates 2015 to 2020
437
9.6
Competitive Analysis and Market Share
449
Emerging Technologies
451
10.1
Overview of Condition and Treatment
451
10.2
Competitive Advantage
453
10..3
Manufacturer Profiles and Product Descriptions
455
www.miinews.com
10.3.1
Allergan
455
10.3.2
Alma Lasers
457
10.3.3
Croma-Pharma
457
10.3.4
Excaliard Pharmaceuticals / Pfizer
457
10.3.5
Halscion
458
10.3.6
Jeisys
458
10.3.7
Miramar Labs
459
10.3.8
Neothetics (formerly Lithera)
460
10.3.9
NovaThreads / CosmoFrance
460
10.3.10
Revance Therapeutics
461
10.3.11
Sinclair
462
10.3.12
V SoftLift AB
463
Medical Insight, Inc.
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Global Aesthetic Market XIV
10.3.13 10.4 11.0
June 2016
463
Viviscal
464
Product Sales Estimates 2015 to 2020
Home-Use Devices
466
11.1
Overview of Condition and Treatment
466
11.2
Competitive Advantage
467
11.3
Product Descriptions and Results
469
11.4
Manufacturer Profiles
472
www.miinews.com
11.4.1
Apira
472
11.4.2
Beautyko
473
11.4.3
Biotechnique Avance
473
11.4.4
Carol Cole Company
474
11.4.5
DermaConcepts
474
11.4.6
Evis Beauty
475
11.4.7
evoDerma
475
11.4.8
Freedom Laser Therapy
476
11.4.9
Guangzhou Charming Electronic Company
476
11.4.10
Home Skinovations
476
11.4.11
Illuminage Beauty
477
11.4.12
JeNu Biosciences
478
11.4.13
LaserCap Company
479
11.4.14
Lexington International
479
11.4.15
Light4Beauty
481
11.4.16
L’Oreal
481
11.4.17
nanoTime
482
11.4.18
Philips
483
11.4.19
PhotoMedex
484
11.4.20
Pollogen
485
11.4.21
Quasar Biotech
486
11.4.22
Reckitt Benckiser
486
11.4.23
Rio (Dezac Group)
486
11.4.24
Spectrum Brands / Remington
487
11.4.25
Spencer Forrest
488
Medical Insight, Inc.
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Global Aesthetic Market XIV
11.5 12.0
13.0 I
II
June 2016
11.4.26
Super Grow Lasers
488
11.4.27
Theradome
489
11.4.28
Tria Beauty
489 490
Market Forecasts
Total Market
498
12.1
Total Market
498
12.2
Procedure Volume and Fees
509
12.3
Market Share
511
Aesthetic Practice Trends
514
Treatment Comparison
567
I.I
Perceived Value
540
I.II
Safety vs. Efficacy
544
I.III
Treatment Compatibility
547
I.IV
Non-Physician Performed Treatments
548
Company Listings
www.miinews.com
574
Medical Insight, Inc.
16
Global Aesthetic Market XIV
M.I.I.
June 2016
Table Of Exhibits
Table 3-1
Energy-Based Types
34
Table 3-2
Average Electolysis Treatment Times
43
Table 3-3
Laws Related to Operation of Laser Hair Removal Devices by State
45
Table 3-4
Top Energy-Based Hair Removal Devices
51
Table 3-5
Top Skin Rejuvenation Devices
56
Table 3-6
Fractional Skin Rejuvenation Devices
61
Table 3-7
Top Tattoo and Pigmented Lesion Removal Devices
63
Table 3-8
Top Energy-Based Acne Devices
65
Table 3-9
Top Energy-Based Vaginal Rejuvenation Devices
68
Table 3-10
Top Energy-Based Vascular Lesion Removal Devices
70
Table 3-11
Worldwide Projected Dollar Sales for Top Manufacturers of Energy-Based Device Platforms
108
Figure 3-1
Worldwide Dollar Growth for Leading Providers of Energy-Based Device Platforms
109
Table 3-12
North American Projected Dollar Sales for Top Manufacturers of EnergyBased Device Platforms
110
Figure 3-2
North American Dollar Growth for Leading Providers of Energy-Based Device Platforms
111
Table 3-13
European Projected Dollar Sales for Top Manufacturers of Energy-Based Device Platforms
112
Figure 3-3
European Dollar Growth for Leading Providers of Energy-Based Device Platforms
113
Table 3-14
Asian Projected Dollar Sales for Top Manufacturers of Energy-Based Device Platforms
115
Figure 3-4
Asian Dollar Growth for Leading Providers of Energy-Based Device Platforms
116
Table 3-15
Latin American Projected Dollar Sales for Top Manufacturers of Energy-Based Device Platforms
117
Figure 3-5
Latin American Dollar Growth for Leading Providers of Energy-Based Device Platforms
118
Figure 3-6
Dollar Sales of Energy-Based Device Platforms by Region
119
Table 3-16
Worldwide Projected Dollar Sales for Energy-Based Device Platforms, by Application
120
Figure 3-7
Dollar Sales of Energy-Based Device Platforms, by Application
121
Table 3-17
Worldwide Projected Dollar Sales for Top Manufacturers of Energy-Based Device Disposables
122
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Figure 3-8
Worldwide Dollar Sales of Energy-Based Device Disposables
123
Table 3-18
North American Projected Dollar Sales for Top Manufacturers of EnergyBased Device Disposables
123
Figure 3-9
North American Dollar Sales of Energy-Based Device Dispoables
124
Table 3-19
European Projected Dollar Sales for Top Manufacturers of Energy-Based Device Disposables
125
Figure 3-10
European Dollar Sales of Energy-Based Device Disposables
126
Table 3-20
Asian Projected Dollar Sales for Top Manufacturers of Energy-Based Device Disposables
126
Figure 3-11
Asian Dollar Sales of Energy-based Device Disposables
127
Table 3-21
Latin American Projected Dollar Sales for Top Manufacturers of Energy-Based Device Disposables
127
Figure 3-12
Latin American Dollar Sales of Energy-Based Device Disposables
128
Figure 3-13
Dollar Sales of Energy-Based Device Disposables, by Region
129
Table 3-22
Worldwide Procedure Volume for Energy-Based Aesthetic Treatments
130
Figure 3-14
Worldwide Procedure Fees for Energy-Based Aesthetic Treatments
131
Figure 3-15
Worldwide Procedure Volume for Energy-Based Aesthetic Treatments by Region
132
Figure 3-16
Worldwide Procedure Fees for Energy-Based Aesthetic Treatments by Region
133
Table 3-23
Worldwide Procedure Volume for Energy-Based Aesthetic Treatments by Application
134
Figure 3-17
Worldwide Procedure Volume for Energy-Based Aesthetic Treatments by Application
135
Table 3-24
Worldwide Procedure Fees for Energy-Based Aesthetic Treatments by Application
136
Figure 3-18
Worldwide Procedure Fees for Energy-Based Aesthetic Treatments by Application
136
Figure 3-19
Average Number of Weekly Energy-Based Hair Removal Treatments
137
Figure 3-20
Average Charge for Single Energy-Based Hair Remvoal Treatment
138
Figure 3-21
Average Number of Weekly Energy-Based Skin Rejuvenation Treatments
139
Figure 3-22
Average Charge for Single Energy-Based Skin Rejuvenation Treatment
140
Figure 3-23
Average Number of Weekly Energy-Based Feminine Rejuvenation Treatments
141
Figure 3-24
Average Charge for a Single Energy-Based Feminine Rejuvenation Treatment
142
Table 3-25
Market Shares of Leading Manufacturers of Energy-Based Aesthetic Platforms and Disposables
143
Figure 3-25
Market Shares for Leading Manufacturers of Energy-Based Aesthetic Equipment
144
Table 4-1
Leading Body Shaping and/or Cellulite Reduction Devices
149
Table 4-2
Leading Skin Tightening Devices
152
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Table 4-3
Worldwide Projected Dollar Sales for Top Manufacturers of Body Shaping & Skin Tightening Device Platforms
192
Figure 4-1
Worldwide Sales Growth of Body Shaping & Skin Tightening Platforms
193
Table 4-4
North American Projected Dollar Sales for Top Manufacturers of Body Shaping & Skin Tightening Device Platforms
194
Figure 4-2
North American Sales Growth of Body Shaping & Skin Tightening Platforms
195
Table 4-5
European Projected Dollar Sales for Top Manufacturers of Body Shaping & Skin Tightening Device Platforms
196
Figure 4-3
European Sales Growth of Body Shaping & Skin Tightening Platforms
197
Table 4-6
Asian Projected Dollar Sales for Top Manufacturers of Body Shaping & Skin Tightening device Platforms
198
Figure 4-4
Asian Sales Growth of Body Shaping & Skin Tightening Platforms
199
Table 4-7
Latin American Projected Dollar Sales for Top Manufacturers of Body Shaping & Skin Tightening Device Platforms
200
Figure 4-5
Latin American Sales Growth of Body Shaping & Skin Tightening Platforms
201
Figure 4-6
Dollar Sales of Body Shaping & Skin Tightening Device Platforms by Region
202
Table 4-8
Worldwide Projected Dollar Sales for Top Manufacturers of Body Shaping & Skin Tightening Device Disposables
203
Figure 4-7
Worldwide Dollar Sales of Body Shaping & Skin Tightening Device Disposables
204
Table 4-9
North American Projected Dollar Sales for Top Manufacturers of Body Shaping & Skin Tightening Device Disposables
205
Figure 4-8
North American Dollar Sales of Body Shaping & Skin Tightening Device Disposables
206
Table 4-10
European Projected Dollar Sales for Top Manufacturers of Body Shaping & Skin Tightening Device Disposables
207
Figure 4-9
European Dollar Sales of Body Shaping & Skin Tightening Device Disposables
208
Table 4-11
Asian Projected Dollar Sales for Top Manufacturers of Body Shaping & Skin Tightening Device Disposables
209
Figure 4-10
Asian Dollar Sales of Body Shaping & Skin Tightening Device Disposables
210
Table 4-12
Latin American Projected Dollar Sales for Top Manufacturers of Body Shaping & Skin Tightening Device Disposables
211
Figure 4-11
Latin American Dollar Sales of Body Shaping & Skin Tightening Device Disposables
212
Figure 4-12
Dollar Sales of Body Shaping & Skin Tightening Device Disposables by Region
213
Table 4-13
Worlwide Procedure Volume for Body Shaping & Skin Tightening
214
Figure 4-13
Worldwide Procedure Fees for Body Shaping & Skin Tightening
215
Figure 4-14
Worldwide Procedure Volume for Body Shaping & Skin Tightening by Region
216
Figure 4-15
Worldwide Procedure Fees for Body Shaping & Skin Tightening by Region
217
Figure 4-16
Average Number of Weekly Energy-Based Skin Tightening Treatments
218
Figure 4-17
Average Charge for Single Energy-Based Skin Tightening Treatment
219
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Figure 4-18
Average Number of Weekly Energy-Based Body Shaping Treatments
220
Figure 4-19
Average Charge for Single Energy-Based Body Shaping Treatment
221
Table 4-14
Worldwide Market Shares of Body Shaping & Skin Tightening Platforms and Disposables
222
Figure 4-20
Change in Market Shares of Body Shaping & Skin Tightening Platforms
223
Table 5-1
Leading Neurotoxins
227
Figure 5-1
BOTOX Injection Points
231
Figure 5-2
BOTOX Injection Points for Lateral Canthal Lines
232
Table 5-2
Worldwide Projected Dollar Sales for Leading Neurotoxins
242
Figure 5-3
Worldwide Sales Growth of Neurotoxins
243
Table 5-3
North American Projected Dollar Sales for Leading Neurotoxins
244
Figure 5-4
North American Sales Growth of Neurotoxins
245
Table 5-4
European Projected Dollar Sales for Leading Neurotoxins
246
Figure 5-5
European Sales Growth of Neurotoxins
247
Table 5-5
Asian Projected Dollar Sales for Leading Neurotoxins
248
Figure 5-6
Asian Sales Growth of Neurotoxins
249
Table 5-6
Latin American Projected Dollar Sales for Leading Neurotoxins
250
Figure 5-7
Latin American Sales Growth of Neurotoxins
251
Figure 5-8
Dollar Sales Growth of Neurotoxins by Region
252
Table 5-7
Worldwide Procedure Volume for Neurotoxins
253
Figure 5-9
Worldwide Procedure Fees for Neurotoxins
254
Figure 5-10
Worldwide Procedure Volume for Neurotoxins by Region
255
Figure 5-11
Worldwide Procedure Fees for Neurotoxins by Region
256
Figure 5-12
Average Number of Weekly Neurotoxin Patients
257
Figure 5-13
Average Charge for Single Neurotoxin Injection (Single Tx Session)
258
Table 5-8
Worldwide Market Shares of Top Neurotoxin Suppliers
259
Figure 5-14
Change in Market Shares of Top Neurotoxin Suppliers
260
Table 6-1
Leading Dermal Fillers
265
Table 6-2
Characteristics of Selected Dermal Fillers
267
Table 6-3
Projected Worldwide Dollar Sales of Dermal Fillers for Top Suppliers
290
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Figure 6-1
Worldwide Sales Growth of Dermal Fillers
291
Table 6-4
Projected North American Dollar Sales of Dermal Fillers for Top Suppliers
292
Figure 6-2
North American Sales Growth of Dermal Fillers
293
Table 6-5
Projected European Dollar Sales of Dermal Fillers for Top Suppliers
294
Figure 6-3
European Sales Growth of Dermal Fillers
295
Table 6-6
Projected Asian Dollar Sales of Dermal Fillers for Top Suppliers
296
Figure 6-4
Asian Sales Growth of Dermal Fillers
297
Table 6-7
Projected Latin American Dollar Sales of Dermal Fillers for Top Suppliers
298
Figure 6-5
Latin American Sales Growth of Dermal Fillers
299
Figure 6-6
Dollar Sales of Dermal Fillers by Region
300
Table 6-8
Worldwide Procedure Volume for Dermal Fillers
301
Figure 6-7
Worldwide Procedure Fees for Dermal Fillers
302
Figure 6-8
Worldwide Procedure Volume for Dermal Fillers by Region
303
Figure 6-9
Worldwide Procedure Fees for Dermal Fillers by Region
304
Figure 6-10
Average Number of Weekly Dermal Filler Patients
305
Figure 6-11
Average Charge for Single Dermal Filler Injection
306
Market Shares of Top Dermal Filler Suppliers
307
Change in Market Shares of Top Dermal Filler Suppliers
308
Table 7-1
Leading Suppliers of Liposuction Equipment
311
Table 7-2
Projected Worldwide Dollar Sales for Leading Suppliers of Liposuction Equipment
314
Figure 7-1
Worldwide Sales Growth of Liposuction Equipment
315
Table 7-3
Projected North American Dollar Sales for Leading Suppliers of Liposuction Equipment
316
Figure 7-2
North American Sales Growth of Liposuction Equipment
317
Table 7-4
Projected European Dollar Sales for Leading Suppliers of Liposuction Equipment
318
Figure 7-3
European Sales Growth of Liposuction Equipment
319
Table 7-5
Projected Asian Dollar Sales for Leading Suppliers of Liposuction Equipment
320
Figure 7-4
Asian Sales Growth of Liposuction Equipment
321
Table 7-6
Projected Latin American Dollar Sales for Leading Suppliers of Liposuction Equipment
322
Figure 7-5
Latin American Sales Growth of Liposuction Equipment
323
Table 6-9 Figure 6-12
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Figure 7-6
Dollar Sales Growth of Liposuction Equipment by Region
324
Table 7-7
Worldwide Procedure Volume for Liposuction
325
Figure 7-7
Worldwide Procedure Fees for Liposuction
326
Figure 7-8
Worldwide Procedure Volume for Liposuction by Region
327
Figure 7-9
Worldwide Procedure Fees for Liposuction by Region
328
Table 7-8
Worldwide Market Shares for Leading Manufacturers of Liposuction Equipment
329
Change in Market Shares of Leading Manufacturers of Liposuction Equipment
330
Table 8-1
Leading Breast Implant Products
334
Table 8-2
Worldwide Projected Dollar Sales for Leading Manufacturers of Breast Implants
345
Figure 8-1
Worldwide Sales Growth of Breast Implants
346
Table 8-3
North American Projected Dollar Sales for Leading Manufacturers of Breast Implants
347
Figure 8-2
North American Sales Growth of Breast Implants
348
Table 8-4
European Projected Dollar Sales for Leading Manufacturers of Breast Implants
349
Figure 8-3
European Sales Growth of Breast Implants
350
Table 8-5
Asian Projected Dollar Sales for Leading Manufacturers of Breast Implants
351
Figure 8-4
Asian Sales Growth of Breast Implants
352
Table 8-6
Latin American Projected Dollar Sales for Leading Manufacturers of Breast Implants
353
Figure 8-5
Latin American Sales Growth of Breast Implants
354
Figure 8-6
Dollar Sales of Breast Implants by Region
355
Table 8-7
Worldwide Procedure Volume for Breast Implants
356
Figure 8-7
Worldwide Procedure Fees for Breast Implants
357
Figure 8-8
Worldwide Procedure Volume for Breast Implants by Region
358
Figure 8-9
Worldwide Procedure Fees for Breast Implants by Region
359
Table 8-8
Worldwide Market Shares of Top Breast Implant Manufacturers
360
Figure 8-10
Change in Market Shares of Top Breast Implant Manufacturers
361
Table 9-1
Comparison of Benefits: Cosmeceuticals vs. In-Office Treatments
366
Table 9-2
Top Cosmeceutical Ingredients
370
Table 9-3
Top Chemical Peel Suppliers
387
Table 9-4
Eyelash Enhancement Products
392
Figure 7-10
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Table 9-5
Projected Worldwide Sales of Physician-Dispensed Topicals for Top Suppliers
437
Figure 9-1
Worldwide Sales Growth of Physician-Dispensed Topicals
438
Table 9-6
Projected North American Sales of Physician-Dispensed Topicals for Top Suppliers
438
Figure 9-2
North American Sales Growth of Physician-Dispensed Topicals
439
Table 9-7
Projected European Sales of Physician-Dispensed Topicals for Top Suppliers
440
Figure 9-3
European Sales Growth of Physician-Dispensed Topicals
441
Table 9-8
Projected Asian Sales of Physician-Dispensed Topicals for Top Suppliers
442
Figure 9-4
Asian Sales Growth of Physician-Dispensed Topicals
443
Table 9-9
Projected Latin American Sales of Physician-Dispensed Topicals for Top Suppliers
444
Figure 9-5
Latin American Sales Growth of Physician-Dispensed Topicals
445
Figure 9-6
Dollar Growth of Physician-Dispensed Topicals for Top Suppliers by Region
446
Figure 9-7
Do You Currently Sell Skincare Products from Your Practice?
447
Figure 9-8
If Yes, Approximately How Much Revenue Does this Generate Annually?
448
Table 9-10
Worldwide Market Shares of Leading Manufacturers of Physician-Dispensed Topicals
449
Figure 9-9
Change in Global Market Shares of Leading Manufacturers of PhysicianDispensed Topicals
450
Table 10-1
Worldwide Projected Dollar Sales for Emerging Products
464
Figure 10-1
Projected Worldwide Sales of Emerging Products for Top Suppliers
465
Table 11-1
Leading Technology-Based Home-Use Aesthetic Devices Available and Under Development
470
Figure 11-1
Market Shares of Top Home-Use Aesthetic Players by Retails Sales
491
Table 11-2
Projected Worldwide Retail Sales of Aesthetic Home-Use Devices
493
Figure 11-2
Worldwide Aesthetic Home-Use Device Retail Sales by Company
494
Table 11-3
Worldwide Projected Dollar Sales for Leading Aesthetic Home-Use Devices, by Region
495
Table 11-4
Worldwide Projected Retail Sales of Home-Use Aesthetic Devices, Disposables
496
Table 11-5
Worldwide Projected Retail Sales of Home-Use Aesthetic Devices and Disposables
497
Table 12-1
Total Worldwide Sales of Aesthetic Products
498
Figure 12-1
Worldwide Aesthetic Product Sales by Market Segment
499
Table 12-2
Total North American Sales of Aesthetic Products
500
Figure 12-2
North American Aesthetic Product Sales by Market Segment
501
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Global Aesthetic Market XIV
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Table 12-3
Total European Sales of Aesthetic Products
502
Figure 12-3
European Aesthetic Product Sales by Market Segment
503
Table 12-4
Total Asian Sales of Aesthetic Products
504
Figure 12-4
Asian Aesthetic Product Sales by Market Segment
505
Table 12-5
Total Latin American Sales of Aesthetic Products
506
Figure 12-5
Latin American Aesthetic Product Sales by Market Segment
507
Figure 12-6
Worldwide Aesthetic Product Sales by Region
508
Table 12-6
Procedure Volume Growth by Segment in Millions
509
Table 12-7
Procedure Volume Growth by Region in Millions
509
Table 12-8
Procedure Fee Growth by Segment in $ Billions
510
Table 12-9
Procedure Fee Growth by Region in $ Billions
510
Table 12-10
Total Sales of Leading Manufacturers
511
Table 12-11
Market Shares of Leading Manufacturers
512
Figure 12-7
Change in Market Shares of Leading Aesthetic Manufacturers
513
Figure 13-1
Number of Employees in Practice in 2015
515
Figure 13-2
Annual Practice Revenue in 2015
516
Figure 13-3
Average Weekly Aesthetic Patient Volume in 2015
517
Figure 13-4
Do You Expect to Expand Your Staff in 2016?
519
Figure 13-5
Expected Practice Revenue Change in 2016
520
Figure 13-6
Expected Practice Profit Margin Change in 2016
521
Figure 13-7
Did You Implement any Cost Reduction Measures in 2015?
522
Figure 13-8
If Yes, What Cost Reduction Measures did You Implement?
523
Figure 13-9
Do You Plan to Implement any Cost Reduction Measures in 2016?
524
Figure 13-10
If Yes, What Cost Reduction Measures do You Plan to Implement?
525
Figure 13-11
Expected Average Weekly Aesthetic Patient Volume Change in 2016
526
Figure 13-12
Did You Add any New Aesthetic Services in 2015?
527
Figure 13-13
If Yes, Which New Services did You Add?
528
Figure 13-14
Aesthetic Services that Generate the Most Revenue
529
Figure 13-15
Most Profitable Aesthetic Services
530
Figure 13-16
Do You Plan to Add Any New Aesthetic Services in 2016?
531
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Global Aesthetic Market XIV
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Figure 13-17
If Yes, What Services?
532
Figure 13-18
Do You Plan to Discount or Scale Back Any Aesthetic Services in 2016?
533
Figure 13-19
Did you Purcahse / Lease Any New Aesthetic Equipment in 2015?
534
Figure 13-20
If Yes, What Treatments Does This Equipment Perform?
535
Figure 13-21
Do You Plan to Purchase / Lease Any New Equipment in 2016?
536
Figure 13-22
If Yes, What Treatments Will This New Equipment Perform?
537
Figure 13-23
What Trends, If Any, Are You Noticing Among Your Patients?
538
Figure I-I
Selected Facial Treatments Consumer Value Comparison
541
Figure I-II
Selected Energy Devices Consumer Value Comparison
542
Figure I-III
Cosmetic Surgical Consumer Value Comparison
543
Facial Rejuvenation Treatment Comparison
545
Results vs. Risk for Facial Treatments
546
Physician vs. Non-Physician Usage of Aesthetic Procedures
549
Table I-I Figure I-IV Table I-II
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Global Aesthetic Market XIV
June 2016
i. Methodology The Global Aesthetic Market XIV (GAM XIV) represents the fourteenth edition in Medical Insight, Inc.’s Global Aesthetic Market series. This report was compiled from a wide variety of public and proprietary sources. Information was cross-checked against other data, using Medical Insight’s proprietary forecasting models, and synthesized into both qualitative and quantitative analyses and projections, specifically covering medical aesthetic products and equipment; products and equipment designed for therapeutic usage, even when they are produced by leading aesthetic companies, are not included. Therefore, new devices for instance, such as the treatment of onychomycosis are excluded.
Public sources that were utilized for this report include:
-
articles in trade publications and medical journals;
-
articles in consumer magazines and newspapers;
-
company news releases, website information, marketing materials and financial filings;
-
information from trade associations
Proprietary sources that were utilized include: -
Medical Insight’s extensive database of industry and product information;
-
recent Medical Insight survey data;
-
industry analyst reports;
-
exclusive interviews with company executives, researchers, sales representatives, physicians, patients, consultants and other industry experts
Additionally, feedback from Medical Insight product information is continually built back into research products so that reports are updated with the most recent industry and market information on an ongoing basis.
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Global Aesthetic Market XIV
June 2016
ii. New in June 2016 GAM XIV offers an in-depth analysis of the competitive positions of key players in all segments with details obtained from recent interviews.
In addition to the latest industry news and updated market forecasts, which take into account recent technology, product, company, regulatory and other developments, GAM XIII also contains:
-
Extension of sales forecasts from 2015 to 2020;
-
comparison of current forecasts to GAM XIII forecasts and discussion of changes;
-
links to online videos for selected technologies and treatments;
-
analysis of political, economic and other factors impacting the aesthetic market, particularly in the U.S. and Europe
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Global Aesthetic Market XIV
Section
1
June 2016
Executive Summary
In 2015, total sales of professional aesthetic products covered in this report, including disposable components, exceeded $7.6 billion. Through 2020, they will expand by 11.0% per year to $12.8 billion. This is lower than the compound annual growth of 11.8% predicted in GAM XIII, released in early 2015 as forecasts were adjusted to reflect the ongoing global economic uncertainty. Growth will be driven by significant increases in the body shaping / skin tightening segment along with continued expansion of neurotoxins and dermal fillers. The energy-based devices and physiciandispensed topicals markets will also experience reasonable annual gains of 6.5% and 7.5%, respectively, as demand for these products results in increased sales.
In 2015, the leading companies profiled in this report accounted for total professional aesthetic product sales of about $5.5 billion, representing approximately 73% of the total market. Their sales will rise by 11.5% per year to reach more than $9.5 billion in 2020.
In 2015, total global procedure volume reached 59 million treatments with compound annual growth of 6.3% anticipated through 2020. Procedure volume growth will be greatest in the body shaping / skin tightening, neurotoxin and dermal filler sectors. On a global basis, procedure volume will grow most strongly in Asia and Latin America. In 2015, total global procedure fees were about $26 billion, with compound annual growth predicted of 5.4% through 2020. As with procedure volume, procedure fee growth will be greatest in the body shaping / skin tightening, neurotoxin and dermal filler sectors. On a global basis, procedure fees will grow most strongly in Asia and Latin America.
The aesthetic market was notable in 2015 and 2016 for the continuing consolidation of companies and changing regulatory environment with the U.S. Department of Treasury curbing U.S. company inversions to domiciles with more favorable tax laws. Most notable was the successful acquisition and inversion of Allergan by Actavis (the consolidated company is named Allergan), and the subsequent potential merger with Pfizer that was called off after the U.S. Treasury intervened.
The aesthetic market continues to be of interest for both pharma and consumer companies wanting to diversify into a sector that is showing strong growth, is highly profitable and has characteristics of both a consumer packaged goods and traditional pharmaceutical model. This is exemplified by Almirall, a Spanish based pharma company that has entered the aesthetic market by
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acquiring Thermi (energy-based body shaping and skin tightening) and also partnering with Suneva (dermal filler). Also notable is the topical skincare market where companies such as Unilever, which acquired various skincare brands in 2015, namely REN, Murad, Dermalogica and Kate Somerville Skincare to add to their portfolio of other skincare brands. Unilever Ventures also has a joint venture with Syneron, namely iLuminage Beauty, which is developing products for the home-use market.
The acquisition of technologies continues such as with the purchase of both Kythera and Anterios by Allergan, and the forming of new beneficial collaborations such as Galderma and ZELTIQ. The acquisition of Kythera gave Allergan, Kybella which is the first-of-its-kind body sculpting injectable that treats submental fat, while Anterios gave Allergan a new platform to deliver botulinum toxins topically for indications such as crow's feet lines and hyperhidrosis. Galderma and ZELTIQ are collaborating to promote their respective injectable portfolio and CoolScupting brands and connecting these through ASPIRE, a patient and physician loyalty program.
Energy-based device companies are also improving technologies and introducing new treatment modalities that are expanding indications. These include new body sculpting devices such as Sculpsure from Cynosure, which is the first FDA approved laser treatment for non-invasive lipolysis of the flanks and abdomen and the introduction of a number of new devices for feminine rejuvenation / women’s health, which potentially could become a large market segment in itself with brands such as Viveve from Viveve, Inc., MonaLisa Touch from DEKA / Cynosure and ThermiVa from Thermi. The aesthetic market is also being enhanced with the introduction of new business models such as service companies like RegimenMD that has introduced a new distribution channel for professional skincare products designed to help physicians maintain a professional relationship with their patients by supplying products directly to the physician’s patients. To date 20 major manufacturers are partnering with RegimenMD including SkinMedica, NeoStrata, Jan Marini, Skinceuticals, MDRejuvena and Nuvesse Skin Therapies.
Along with these various successes have been challenges as exhibited with the breast implant market where Silimed (distributed by Sientra in the U.S.) withdrew its implants from the market to resolve manufacturing issues. This was further compounded with a fire that will impact the supply of Silimed implants globally for an unspecified time while production is restored.
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June 2016
Figure 5-3 Worldwide Sales Growth of Neurotoxins, 2015 – 2020
2,000.0 1,800.0
Revenue $MMs
1,600.0 1,400.0 1,200.0 1,000.0 800.0 600.0 400.0 200.0 0.0 2015
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2016
2017
2018
2019
Allergan Medical
Alphaeon/ Daewoong
Daewoong
Galderma
Lanzhou Institute
MedyTox
Merz
Other
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2020
30