Felice Petraglia, M. D

05.05.2015 CV Felice Petraglia, M. D. 1. POSITION Professor of Obstetrics and Gynecology University of Siena, Siena, Italy www. unisi.it/obgyn 2. O...
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05.05.2015

CV Felice Petraglia, M. D. 1. POSITION

Professor of Obstetrics and Gynecology University of Siena, Siena, Italy www. unisi.it/obgyn

2. OFFICE ADDRESS

Obstetrics and Gynecology Dept. of Molecular and Development Medicine University of Siena Policlinico “Santa Maria delle Scotte” Viale Bracci 53100 Siena, Italy Phone: +39 0577 233453 Fax: +39 0577 233454 E-mail: [email protected]

3. HOME ADDRESS

Via di Città, 46 53100 Siena, Italy Phone: +39 0577 42426

4. DATE OF BIRTH

November 15, 1956

5. NATIONALITY

Italian

6. FAMILY

Married (Silvia), with two daughters (Maria Grazia 30 years old and Enrica 25 years old)

7. EDUCATION 1980 1984 1987 8. CAREER 1985 - 1987 1988 - 1992 1992 - 1997 1995 - 1996 1997 - 2000 2000 -

Medical Doctor, University of Siena, Siena, Italy Specialist in Obstetrics and Gynecology Specialist in Endocrinology.

Visiting Scientist at the Salk Institute, La Jolla, California, USA Fellow at Obstetrics and Gynecology, University of Modena, Italy Associate Professor Obstetrics and Gynecology, University of Modena, Italy Visiting Associate Professor Obstetrics and Gynecology, University of Pisa, Italy Professor of Obstetric and Gynecology University of Udine, Italy. Professor of Obstetric and Gynecology University of Siena, Italy

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9. ACADEMIC APPOINTMENTS 2002-2008 Director of the Department of Pediatrics, Obstetrics and Reproductive Medicine, University of Siena, Siena, Italy 2000Chair of the School of Specialization in Obstetrics and Gynecology, University of Siena 2000-2010 Chair of the PhD Program in Medical Biotechnologies in Obstetrics and Gynecology, University of Siena 2011-2014 Chair of the PhD Program in Molecular Medicine, University of Siena 2005Adjunct Professor at the Department of Obstetrics and Gynecology, University of Toronto, Toronto, Canada. 2008Interuniversity Research Center for Reproduction Diseases (CIRMAR) 10. HOSPITAL AFFILIATION 1988-1992 Director Menopause Center, University of Modena, Modena, Italy 1992-1995 Attending Staff, Obstetrics and Gynecology, University of Modena, Modena, Italy 1997-2000 Director Division of Obstetrics and Gynecology, University of Udine, Udine, Italy 2000Director Division of Obstetrics and Gynecology, University of Siena, Siena, Italy 2007-2010 Director Department of Maternity and Infancy, University of Siena, Siena, Italy 201311. NATIONAL and INTERNATIONAL APPOINTMENTS Medical Research Council of Canada Australian Medical Research Council Royal College of Obstetricians and Gynecologists -. Scientific Advisory Board MRC, The University of Edinburgh , UK Evaluation Committee Couraud Institut Cochin, Paris Wellcome Trust Swiss National Science Foundation Research Grants Council Hong Kong United States-Israel Binational Science Foundation Italian Ministry of University and Research (MIUR) Italian Ministry of Health Italian Drug Agency (AIFA) as National expert of Obstetrics and Gynecology (2011-2012) 12. GRANT AWARDS 1989-1992 Italian National Research Council (CNR):”Role of inhibin and activin in human pregnancy” 1993-1998 Italian National Research Council (CNR): “Mechanism of onset of labor” 2000-2001 Italian Ministry University (MIUR): “Gestational liver disease: role of activin / inhibin / follistatin” 2002-2003 Italian Ministry University (MIUR): “Identification and role of Placental regulatory factors in maternal – fetal homeostasis” 2006-2007 Italian Ministry University (MIUR): “Placental Biochemical and Biophysical markers for gestational disorders” 2008-2009 Italian Ministry University (MIUR) :”Preterm birth: the obstetric syndrome” 2010-2013 Italian Ministry University (MIUR) :” Preterm birth: placental biochemical and biophysical markers of placental fetal unit”

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13. PATENTS 1) United States Patent Application Pubblication - Method and System for Fetal Weight Evaluation, US 2007/0038093A1 2) European Patent Aplication -Method and System for Foetal Weight Evaluation, EP 1743581A1 3). United States Patent and Trademark Office –{ for serum markers of prostate cancer }, filed in the United States on April 28, 2008 with deposit number 61/048,412 14. PROFESSIONAL HONORS 1988 Republic of San Marino Award on Reproductive Medicine 1992 “C. Pansini” Award of the Italian Society of Obstetrics and Gynaecology 1999 “PG Chiodini” Award of the Italian Society of Endocrinology 2001 International Award “Arnaldo Bruno” National Academy of Lincei 2007 Endocrine Society Award for Excellence in publications in the Journal of Clinical Endocrinology and Metabolism in 2007. 2010 Fellow ad Eundem of the Royal College of Obstetricians and Gynaecologists (RCOG) 2011 McIlrath Guest Professorship, Sydney, Australia 2014

Rogerio A. Lobo Award for the publication on Reproductive Sciences

15. PROFESSIONAL SOCIETY COMMITTEE APPOINTMENTS 2015Board of the Society of Endometriosis and Uterine Disorders (SEUD) 2008-2009 President of the Society for Gynecological Investigation (SGI) 2012Steerring Committee on Infertility, WHO 2010-2012 Executive Board of the International Federation of Gynecology and Obstetrics (FIGO) 2003-2006 Membership Committee of the Endocrine Society 1994-2012 Executive Committee of International Society Gynecological Endocrinology (ISGE) 2006-2010 Council of European Board and College Obstetrics and Gynecology (EBCOG) 2004-2007 Deputy of the Special Interest Group on Reproductive Endocrinology of the European Society Human Reproduction Embriology (ESHRE) 1996-1999 Scientific Committee of the European Association of Gynaecologist and Obstetrician (EAGO) 2012-2014 Scientific Board of European Endometriosis League (EEL) 2008Advisor of Endometriosis Association 2011Correspondent Member of the Pontificial Academy for Life (PAL) 2003-2007 Council of the Society for Gynecological Investigation (SGI) 2001-2007 Executive Committee Italian Association for University Gynecologist (AGUI) 2001-2007 Scientific Committee Italian Society of Reproductive Pathophysiology 1992-1994 Scientific Committee of the Italian Society of Endocrinology 1997-2007 Executive Committee of the Italian Association Placenta 2011-2012 President of the Italian Society for Reproduction 2013Miembro Honorario Extraniero of Federacion Argentina de Sociedades de Ginecologia y Obstetricia (F.A.S.G.O)

16. PROFESSIONAL SOCIETY MEMBERSHIP Society for Reproductive Investigation (SRI) Society of Endometriosis and Uterine Disorders (SEUD) International Society of Gynecological Endocrinology (ESHRE) European Society of Human Reproduction and Embriology (ESHRE) 3

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Italian Society of Obstetrics and Gynecology (SIGO) Italian Society of Reproduction (SIDR) Italian Association University Gynecologists

17. EDITORIAL EXPERIENCE Editor- in - Chief 20132009-2012

Human Reproduction Udpate Journal of Endometriosis

Associate Editor : 2007- 2012 2004-2012 2005-2009

Reproductive Sciences Journal of Endocrinological Investigation Human Reproduction Update

Advisory Board 2005-

Editorial Board: 199920002002-2014 2007-2012 2007-2012 2007-2012 2011-2012 1993-1999 1995-1999 1997-2004 1993-1998 2001- 2007

Faculty of 1000 Medicine website (Section Head in Reproductive Endocrinology)

References en Gynecologie Obstetrique Gynecological Endocrinology Prenatal and Neonatal Medicine Reproductive Biology Insight The Open Endocrinology Journal Open Endocrinology Review World Journal of Obstetrics and Gynecology Journal of Endocrinological Investigation Journal Clinical Endocrinology and Metabolism European Journal of Endocrinology Placenta Journal of Society Gynecological Investigation

Contributor for the online Series Up-to-date in Obstetrics and Gynaecology (2000-) Peer-Reviewer for more than 30 Journals: American Journal of Obstetrics and Gynecology, Obstetrics and Gynecology, Reproductive Sciences, Journal of the Society for Gynecologic Investigation, Fertility and Sterility, British Journal of Obstetrics and Gynecology, Human Reproduction Update, Human Reproduction, Molecular Human Reproduction, Biology of Reproduction, Reproduction, Fertility and Development, Placenta, Gynecological Endocrinology, -Journal of Clinical Investigation, Life Sciences, Journal of Clinical Endocrinology & Metabolism, Endocrinology, Endocrine Review, Clinical Endocrinology, Journal of Endocrinology, Neuroendocrinology, Journal of Neuroendocrinology, Endocrine, Acta Endocrinology, European Journal of Endocrinology, Journal of Endocrinological Investigation, Diabetologia, Aging, Cellular and Molecular Neurobiology, Molecular and Cellular Neurosciences, Journal of Hypertension.

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Publications: -Author or co-Author of 652 original papers in International Journals on Impact Factor total = 2423.23 Hirsch Index =60 - Citations: 14.499 -Contributor of the Textbook “Physiology of Reproduction” Knobil and Neill’s (2006) -Contributor for the online series Uptodate in Obstetrics and Gynecology (2000- ) -Co-Editor of 27 scientific volumes in particular: - Brain and Female Reproductive Function (1988), - Hormones in Gynecological Endocrinology (1992), - Neuroendocrinology of Female Reproductive Function (1993), - Inhibin and inhibin-related proteins (1995), - The Brain: Source and Target of Sex Steroid Hormones (1996), - Paracrine mechanisms in female reproduction (1997), - Progestins, Progesterone Receptors Modulators and Progesterone Antagonists (2003), - Preterm Birth: Mechanisms, Mediators, Prediction, Prevention and Interventions (2005). 18. INVITED LECTURES International Seminars (n. 46) in particular: 1986 Universite' de Geneve ,Geneve, Switzerland University of California San Diego, San Diego, USA Columbia University, New York, USA 1988

University of California San Diego, San Diego, USA Fukui University, Fukui, Japan

1989

University of California San Francisco, San Francisco, USA Loma Linda University Loma Linda, USA The Clayton Foundation, Salk Institute, La Jolla, USA

1990

University of California San Diego, San Diego, USA Harvard Med. School, Boston, USA

1991

Genentech, San Francisco, USA University of Texas, Dallas, USA Monash University, Melbourne, Australia University of Newcastle, Newcastle, Australia Istitut Gustav Roussy, Paris, France

1992 St. Bartholome's Medical College, Londra, UK University of Reading, Reading, UK 1993

University of Heidelberg, Heidelberg, Germany

1994

Columbia University, New York, USA Mount Sinai Medical School, New York, USA Monash University, Melbourne, Australia Institut Gustave-Roussy, Paris, France 5

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1995

University Western Ontario, London, Canada Peking Union Med. College, University of Xian e University of Shangai, Chine

1996

Emory University Mount Sinai Medical School, New York, USA University of California Irvine, Irvine, USA Salk Institute, La Jolla, USA Yale University, New Haven, USA Kobe University, Kobe, Japan

1999

New York University, New York, USA

2000

Istitut Gustav Roussy, Parigi, Francia

2002

Istitut Gustav Roussy, Parigi, Francia

2004

Penn University Philadelphia, USA Temple University of Philadelphia, Philadelphia, USA George Town University of Washington, Washington, USA

2006

Mount Sinai Hospital, Toronto, Canada

2007

Yale University, New York, USA University of Medicine & Dentistry of New Jersey, Newark, USA

2008

Mother-Child Hospital , Kobe, Japon

2010

New Jersey, Medical Dental School, Newark,USA Mount Sinai Hospital , New York, USA

2011

University of Giessen, Giessen, Germany University of Sydney , Sidney, Australia University of Edinburgh, Edinburgh, UK

2012

University of Guangzhou, Guangdong, China

2014

H.B. Atlee Lecture, Halifax University, Nova Scotia, Canada National University Hospital, Singapore

2015

National University Hospital, Singapore

International Meetings (n. 116) in particular: 1988 First CONRAD Conference on “Non-steroidal Contraceptives”, Norfolk, USA International Symposium on “Placental Protein Hormone, Kobe, Japan VIII Congress International Society of Endocrinology, Kyoto, Japan 1989 Symposium “Gametogenesis and Development Reproductive Organs” Touraine, France IV Congress European Association of Neuroendocrinology, Santiago Campostela, Spain 1990 II Congress International Society of Gynecological Endocrinology, Jerusalem, Israel First Conference on the Primate Endometrium, New York, USA VII World Congress on Human Reproduction, Helsinki, Finland Beijing International Symposium on Reproductive Biology, Beijing ,Chine 6

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1991

1992 1993

1994 1995

1996

1997

1998 1999

2000

2001 2002 2003

2004 2005

2006

2007 2008

International Symposium on “Stress and Reproduction” Port Douglas, Australia IV Meet. Europ. Placenta Group & Rochester Trophoblast Conf., Gwatt, Switzerland The Neuroendocrinology of Sex Steroids, Ulm, Germany Corticotropin Releasing Factor, London, England XIV World Congress of Fertility and Sterility, Caracas, Venezuela VIII World Congress on Human Reproduction, Bali, Indonesia II World Congress of Perinatal Medicine, Rome, Italy International Congress on Menopause, Rosario, Argentina IX International Congress on Hormonal Steroids, Dallas, USA 1st Congress of World Placenta Association, Sydney, Australia 10th Congress European Ass. Gynecologists Obstetricians, Montecarlo, France 38th Journee Internationalse Henry-Pierre Klotz, Paris, France World Congress Fertility and Sterility, Montpellier, France IX World Congress on Human Reproduction, Philadelphia, USA The Uterus, New York, USA Inhibin, activin and follistatin recent advances and future views, Tokushima, Japan III World Congress on Labor, Rome, Italy XV Federation Int. Gynecology and Obstetrics World Congress, Copenhagen, Denmark VIII Congress European Neuroendocrine Association, Marseille, France VI World Gynaecological Endocrinology Congress of ISGE, Crans Montana, Switzerland The Young Woman At the raise of the 21th Century, Athens, Greece VII World Congress of Gynecological Endocrinology, Buenos-Aires, Argentina V International Congress on Cell Biology of Reproduction, Cambridge, U.K Controversies in Obstetrics, Gynaecology and Infertility, Praga, Rep. Ceka Endocrine Basis of Reproductive Function, Tampa, USA International Meeting The Early Human Life, Rome, Italy Human Parturition on the beach – 2000 ICE Satellite, Newcastle, Australia Symposium on Inhibin, Activins and follistatins, Melbourne, Australia Annual Congress of Japan Society of Sterility and Fertility, Kobe, Japan 9th World Congress of Gynaecology and Endocrinology, Hong Kong, Japan Workshop of the Havermeyer Foundation, Palm Springs, California, USA Mother and Infant: Perinatal influences on Health, Montreal, Canada 19th Annual meeting ESHRE, Madrid, Spain Key Note Lecture FIGO World Congress Obstetrics and Gynecology, Santiago, Chile 20th Annual Meeting of the European Society of Human Reproduction and Embriology ESHRE), Berlin, Germany 21th Annual Meeting ESHRE, Copenhagen, Denmark III Jornadas Internacionales de Ginecotocologia / IV Jornadas de Obstetricia Y Perinatologia en Pysandu, Pysandù, Uruguay XX Reunião Anual da Federação de Sociedades de Biologia Experimental – FeSBE, Aguas de Lindoia, São Paulo, Brasil 29th Congress of the Polish Gynecological Society of Obstetrics and Gynecology, Poznam, Poland XVIII FIGO World Congress of Gynecology and Obstetrics, Kuala Lumpur, Malaysia Annual Congress of the Japanese Society of Obstetrics and Gynecology, Kyoto, Japan Annual Congress of the Hellenic Society of Fertility and Sterility, Thessaloniki, Greece Munro Kerr Society Spring Meeting, Glasgow U.K Women’s Health & Disease, Athens, Greece Obstetrics Forum, Amsterdam, The Netherlands COGI Symposium, Paris, France 7

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2009 2010

2011

2012

2013

2014

2015

11°th Hellenic Congress in Obstetrics and Gynecology, Athens, Greece 3rd International SGI Summit Sendai, Japan Controversies in Obstetrics, Gynecology and Infertility, Berlin, Germany ESHRE Campus, Amsterdam, The Netherlands EBCOG Congress, Antwerpen, Belgium Brazilian Endometriosis Society, Sao Paulo,Brasil ESHRE Campus, Valencia, Spain New York Society Ob. Gyn , New York, USA SGI Annual Meeting, Miami, Florida, USA 4th International SGI Summit, Belo Horizonte, Brasil World of Endometriosis Society, Montpellier, France European Society of Gynecology, Copenhagen , Denmark ESHRE Campus on Endometriosis, Rome, Italy 6th International Congress on Reproductive Medicine, Moscow, Russia SGI Annual Meeting, San Diego, California, USA FIGO World Congress, Rome, Italy 1 th European Congress on Endometriosis, Siena, Italy Egyptian Fertility and Sterility Society, Cairo, Egypt SGI Annual Meeting, Orlando, USA II European Congress on Endometriosis, Berlin, Germany German Reproductive Society Meeting, Munster, Germany SGI Annual Meeting, Florence, Italy Symposium on Women’s Health, Ho Chi Minh City, Vietnam Egyptian Fertility and Sterility Society, Cairo, Egypt 1st Congress of Society Endometriosis and Uterine Disorders, Paris, France Symposium on Women’s Health , Jakarta, Indonesia Asia Pacific Endometriosis Courses, Singapore

19. ORGANIZATION OF SCIENTIFIC MEETINGS - Member of the Scientific Board of 25 International Meetings in particular:  1989- Brain-Gut Peptides in Reproduction, Pullman (USA),  1994- First Congress World Placenta Associations, Melbourne (Australia),  1996- Mediterranean Gynecological Conference, Eilat (Israele),  1996.- Banff Trophoblast Conference, Banff (Canada),  1997- III International Conference on Reproductive Endocrinology, Pechino (Cina),  1999- X World Congress on Human Reproduction, Salvador Bahia (Brasile),  2000- IV World Congress on Inhibins, activin and follistatins, Melbourne (Australia),  2001- Controversies in Obstetrics Gynecology & Infertility, Parigi,  2003- Mother and Infant: Perinatal influences on health, Montreal, Canada,  2005- 5th International Conference on Reproductive Endocrinology, China - Scientific Secretary of 20 International Meetings - President:  2002 – 2nd International Symposium on Progestins, Progesterone Receptor Modulators and Progesterone Antagonists  2003 – Serono Symposia on “ Inhibins and Related Proteins”  2005 – 1st International SGI Summit on Preterm Birth;  2005 – ESHRE Campus Course Molecular Biology for Reproductive Medicine specialist Siena, Italy;  2006 – ESHRE Campus Course Molecular Biology for Reproductive Medicine specialist Siena, Italy; 8

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 2007 – ESHRE Campus Course Molecular Biology for Rreproductive Medicine specialist Thessaloniki, GR;  2008 – ESHRE Campus Course Molecular Biology for Rreproductive Medicine specialist; Utrecht, NL;  2008 – SGI Forum on “Inflammation and Reproduction”  2009 – 56th Annual Meeting SGI , Glasgow (UK)  2010 – SGI Forum “Sex Steroid Hormones, Genes and Women’s Health“, Siena, Italy  2012 – 1 st European Congress on Endometriosis, Siena, Italy

20. COORDINATION GOOD CLINICAL PRACTICE -trained in ICH- GCP -1998-2009 coordinator of more than 18 studies in GCP

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